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PDNNRFVPPNSTVEVLGNVPDSTLRRLKQYSGRLATEAVHAMEERLPFFADMEASQRASVQLVVQTAVVN FVEWMRDPQSDVSYTAQAFEVVPQDLRRRIALRQSVEMVRTTMEYFEEVVPLLARSEDQLTALTAGILRY SRDLAFAAASAYADQAEARGAWDTRIESNLVDAVVRGDIGPDLQSQAAALNWDATAPATVIVGTPRPDRT EFVVDDVHDVVKRHGRAALSDVHGTWLVAIVSGNLSPTDRFLAELMSVFADGPVVIGPTAATLGGAHRSA TEAVAGMNSVAGWPGAPRPVAARELLPERALLGDVTAATALEAEVMRPLADAGPALMDTLDAYLDSGGAI EACARKLFIHPNTVRYRLKRITDFTGRDPTVPRDAYVLRVASSLGRLTRQASQSPPLSARSGPRGGVASV TNPGTSP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2780 | - | - | 100% (428) | hypothetical protein Mflv_2780 |
| M. gilvum PYR-GCK | Mflv_0936 | - | 3e-11 | 25.69% (288) | hypothetical protein Mflv_0936 |
| M. gilvum PYR-GCK | Mflv_0801 | - | 3e-07 | 32.48% (117) | transcriptional regulator, CdaR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2266 | - | 1e-172 | 74.45% (407) | hypothetical protein Mb2266 |
| M. tuberculosis H37Rv | Rv2242 | - | 1e-172 | 74.45% (407) | hypothetical protein Rv2242 |
| M. leprae Br4923 | MLBr_01652 | - | 1e-169 | 72.24% (407) | hypothetical protein MLBr_01652 |
| M. abscessus ATCC 19977 | MAB_1880c | - | 1e-160 | 66.28% (430) | hypothetical protein MAB_1880c |
| M. marinum M | MMAR_3335 | - | 1e-169 | 71.60% (419) | hypothetical protein MMAR_3335 |
| M. avium 104 | MAV_2195 | - | 1e-167 | 72.80% (397) | hypothetical protein MAV_2195 |
| M. smegmatis MC2 155 | MSMEG_4324 | - | 0.0 | 80.05% (426) | hypothetical protein MSMEG_4324 |
| M. thermoresistible (build 8) | TH_1338 | - | 0.0 | 79.43% (423) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1307 | - | 1e-168 | 71.36% (419) | hypothetical protein MUL_1307 |
| M. vanbaalenii PYR-1 | Mvan_3753 | - | 0.0 | 85.04% (421) | hypothetical protein Mvan_3753 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2780|M.gilvum_PYR-GCK MPDNNRFVPPNSTV-------EVLGNVPDSTLRRLKQYSGRLATEAVHAM
Mvan_3753|M.vanbaalenii_PYR-1 MTDN-RFIPPRSTV-------EVLENVPESTLRRLKQYSGRLATQAVHAM
MSMEG_4324|M.smegmatis_MC2_155 MPDN-RFVPPKSTV-------EVLEAVPDSLLRRLKQYSGRLATEAVHAM
TH_1338|M.thermoresistible__bu VPDN-RFVPPQSTL-------EVLESVPESVLRRLKQYSGRLATEAVHTM
MMAR_3335|M.marinum_M MNDN-QFS-AIARLGSARSPLELLETVPDSLLRRLKQYSGRLATEAVSAM
MUL_1307|M.ulcerans_Agy99 MNNN-QFS-AIARLGSARSPLELLETVPDSLLRRLKQYSGRLATEAVSAM
Mb2266|M.bovis_AF2122/97 MNDN-QLA-PVARP---RSPLELLDTVPDSLLRRLKQYSGRLATEAVSAM
Rv2242|M.tuberculosis_H37Rv MNDN-QLA-PVARP---RSPLELLDTVPDSLLRRLKQYSGRLATEAVSAM
MLBr_01652|M.leprae_Br4923 MNHN-HFV-PAPPR---RLPLELLDTVPDSLLRRLKQYSGRLATEAVTAM
MAV_2195|M.avium_104 MNDN-PFAGPFAKHP--RSPLETLDTVPESVLRRLKQYSGRLATEAVSVM
MAB_1880c|M.abscessus_ATCC_199 MPDN-PATAPRGFR--AARKPRERAEVPEALLHRIKQYSGRLSTEAVHVM
: .* . . **:: *:*:*******:*:** .*
Mflv_2780|M.gilvum_PYR-GCK EERLPFFADMEASQRASVQLVVQTAVVNFVEWMRDPQSDVSYTAQAFEVV
Mvan_3753|M.vanbaalenii_PYR-1 EERLPFFAELDASQRASVQLVVQTAVVNFAEWMRDPRSNVSYTAQAFEVV
MSMEG_4324|M.smegmatis_MC2_155 EQRLPFFAELDASQRASVQLVVQTAVVNFVEWMRNPESNVGYTAQAFEVV
TH_1338|M.thermoresistible__bu EERLPFFADLEASQRASVHLVVQTAVVNFVEWMRDPRSNVTYTMQAFEVV
MMAR_3335|M.marinum_M QERLPFFADLEASQRASVALVVQTAVVNFAEWMQNPRSDVSYTAQAFELV
MUL_1307|M.ulcerans_Agy99 QERLPFFADLEASQRASVALVVQTAVVNFAEWMQNPRSDVSYTAQAFELV
Mb2266|M.bovis_AF2122/97 QERLPFFADLEASQRASVALVVQTAVVNFVEWMHDPHSDVGYTAQAFELV
Rv2242|M.tuberculosis_H37Rv QERLPFFADLEASQRASVALVVQTAVVNFVEWMHDPHSDVGYTAQAFELV
MLBr_01652|M.leprae_Br4923 QERLPFFADLEASQRASVTLVVQTAVVNFVQWMQNPHSDVSYTAQAFELV
MAV_2195|M.avium_104 QDRLPFFADLEASQRASVSLVVQTAVVNFAEWMQDPKSNVRHTAQAFELV
MAB_1880c|M.abscessus_ATCC_199 EDRLPFFTDLEASQRASVALVVQTAINNFVEWIRDPEGTVGFTMQAFEVV
::*****::::******* ******: **.:*:::*.. * .* ****:*
Mflv_2780|M.gilvum_PYR-GCK PQDLRRRIALRQSVEMVRTTMEYFEEVVPLLARSEDQLTALTAGILRYSR
Mvan_3753|M.vanbaalenii_PYR-1 PQDLRRRIALRQSVEMVRVTMEFFEEVVPLLARSEDQLAAMTAGILRYSR
MSMEG_4324|M.smegmatis_MC2_155 PQDLRRRVALRQSVEMVRTSMEFFEEAVPLLARSEEQLTALTAGILRYSR
TH_1338|M.thermoresistible__bu PQDLTRRIALRQTVEMVRTTMEFFEQVVPLLARSEEQVTALTAGILRYSR
MMAR_3335|M.marinum_M PQDLTRRIALRHTVDMVRVTMEFFEEVVPLLARSEEQLTALTVGILKYSR
MUL_1307|M.ulcerans_Agy99 PQDLTRRIALRHTVDMVRVTMEFFEEVVPLLARSEEQLTALTVGILKYSR
Mb2266|M.bovis_AF2122/97 PQDLTRRIALRQTVDMVRVTMEFFEEVVPLLARSEEQLTALTVGILKYSR
Rv2242|M.tuberculosis_H37Rv PQDLTRRIALRQTVDMVRVTMEFFEEVVPLLARSEEQLTALTVGILKYSR
MLBr_01652|M.leprae_Br4923 PQDLARRIALRHTVDMVRVTMEFFEEVVPLLARSEEQLTALTVGILKYSR
MAV_2195|M.avium_104 PQDLARRIALRHSVEMVRVTMEFFEEVVPLLARSEEQLTALTVGVLKYSR
MAB_1880c|M.abscessus_ATCC_199 PQDLAKRIALRHSVDMVRTAMEFFEEVLPLLARNDEQLVTLTEGILRYSR
**** :*:***::*:***.:**:**:.:*****.::*:.::* *:*:***
Mflv_2780|M.gilvum_PYR-GCK DLAFAAASAYADQAEARGAWDTRIESNLVDAVVRGDIGPDLQSQAAALNW
Mvan_3753|M.vanbaalenii_PYR-1 DLAFAAATAYADQAEARGAWDTRMEANLVDAVVRGGTRPELQSQAAALNW
MSMEG_4324|M.smegmatis_MC2_155 DLAFAAASAYADQAEARGAWDIRMEANIVDAVVRGDTGPELQSQAAALNW
TH_1338|M.thermoresistible__bu DLAFAAATAYADAAEARGAWDTRMEANVVDAVVRGAVGPELQSQAAALNW
MMAR_3335|M.marinum_M DLAFTAASAYADAAEARGTWDSRMEASVVDAVVRGDTGPELLSRAAALNW
MUL_1307|M.ulcerans_Agy99 DLAFTAASAYADAAEARGTWDSRMEASVVDAVVRGDTGPELLSRAAALNW
Mb2266|M.bovis_AF2122/97 DLAFTAATAYADAAEARGTWDSRMEASVVDAVVRGDTGPELLSRAAALNW
Rv2242|M.tuberculosis_H37Rv DLAFTAATAYADAAEARGTWDSRMEASVVDAVVRGDTGPELLSRAAALNW
MLBr_01652|M.leprae_Br4923 DLAFTAATAYADAAEARGTWDSRMEASVVDAVVRGDTGPELLSRAAALNW
MAV_2195|M.avium_104 DLAFTAATAYADAAEARGTWDSRMEASVVDAVVRGDTGPELLSRAAALNW
MAB_1880c|M.abscessus_ATCC_199 DLAFGAASAYAEAAETRGAWDSRLEATVVDAVVRGDTGPDMLSRAAALNW
**** **:***: **:**:** *:*:.:******* *:: *:******
Mflv_2780|M.gilvum_PYR-GCK DATAPATVIVGTPRPDR--------TEFVVDDVHDVVKRHGRAALSDVHG
Mvan_3753|M.vanbaalenii_PYR-1 DATAPATVIVGMPRPDR--------AEFAGDDVHEVADRNGRTALSDVHG
MSMEG_4324|M.smegmatis_MC2_155 DATAPATVIVGLPRADR--------IEMARDDVHAVVRRNDRAALSDVHG
TH_1338|M.thermoresistible__bu DATAPATVVVGLPRPDR--------LEVVSQDVHHVANRHGRTALSDVHG
MMAR_3335|M.marinum_M DTTAPATVVVGTPASARDGS--DG-SERAIQDVRDAAAQHGRAALTDVHG
MUL_1307|M.ulcerans_Agy99 DTTAPATVVVGTPASARDGS--DG-SERAIQDVRDAAAQHGRAALTDVHG
Mb2266|M.bovis_AF2122/97 DTTAPATVLVGTPAPGPNGSNSDGDSERASQDVRDTAARHGRAALTDVHG
Rv2242|M.tuberculosis_H37Rv DTTAPATVLVGTPAPGPNGSNSDGDSERASQDVRDTAARHGRAALTDVHG
MLBr_01652|M.leprae_Br4923 DTTAPATVVVGTPTPNHDGPNGQVSSERASQEVREIAARHGRAALTDVHG
MAV_2195|M.avium_104 DTTAPATVVVGTPAPGRDGSTGPGDSERASQHVRDIAAQHGRAALTDVHG
MAB_1880c|M.abscessus_ATCC_199 DTNAPATVIVGTPRPDI--------IATATTLVHEVAQRHGRGALAVIQG
*:.*****:** * . . *: . ::.* **: ::*
Mflv_2780|M.gilvum_PYR-GCK TWLVAIVSGNLSPTDRFLAELMSVFADGPVVIGPTAATLGGAHRSATEAV
Mvan_3753|M.vanbaalenii_PYR-1 TWLVAIISGGLSPTDRFLSELMTVFADGPVVIGPTAPTLGAAHRSATEAI
MSMEG_4324|M.smegmatis_MC2_155 TWLVTIVSGPLSATDRFLADLMSVFADGPVVIGPTTPTLTAAHRSATEAI
TH_1338|M.thermoresistible__bu TWLVTIVSGALSPTDRFLTDLLDVFADGPVVLGPTAPTLSAAYRSATEAI
MMAR_3335|M.marinum_M TWLVAIVSGHLSPTDKVFKDLLEAFSDGPVVIGPTAPMLTAAYHSASEAI
MUL_1307|M.ulcerans_Agy99 TWLVAIVSGHLSPTDKVFKDLLEAFSDGPVVIGPTAPMLTAAYHSASEAI
Mb2266|M.bovis_AF2122/97 TWLVAIVSGQLSPTEKFLKDLLAAFADAPVVIGPTAPMLTAAHRSASEAI
Rv2242|M.tuberculosis_H37Rv TWLVAIVSGQLSPTEKFLKDLLAAFADAPVVIGPTAPMLTAAHRSASEAI
MLBr_01652|M.leprae_Br4923 TWLVAIISGQLAPTDKFFSDLLHAFSDGPVVIGPTAPMLTAAYHSASEAV
MAV_2195|M.avium_104 TWLVAIVSGQLSPTDKFLGDLLEAFSDGPVVVGPTAPMLTAAYHSASEAI
MAB_1880c|M.abscessus_ATCC_199 TRLLTIVSGPITAHDKFLADLMKVFSDGPVVVGPTAGSLSASHTSAVEAL
* *::*:** ::. ::.: :*: .*:*.***:***: * .:: ** **:
Mflv_2780|M.gilvum_PYR-GCK AGMNSVAGWPGAPRPVAARELLPERALLGDVTAATALEAEVMRPLADAGP
Mvan_3753|M.vanbaalenii_PYR-1 AGMNAVAGWAGAPRPVSARELLPERALLGDATAGAALEAEVMRPLSDAGP
MSMEG_4324|M.smegmatis_MC2_155 SGMNAVAGWPSAPRPVSARELLPERALLGDADAVTALETEVMRPLADAGP
TH_1338|M.thermoresistible__bu AGMNAVAGWSGAPRPVPARELLPERALLGDQTAIAALESEVMRPLADAGP
MMAR_3335|M.marinum_M SGMNAVAGWRGAPRPVLARELLPERALMGDASAIVALHTDVMRPLADAGP
MUL_1307|M.ulcerans_Agy99 SGMNAVAGWRGASRPVLARELLPERALMGDASAIVALHTDVMRPLADAGP
Mb2266|M.bovis_AF2122/97 SGMNAVAGWRGAPRPVLARELLPERALMGDASAIVALHTDVMRPLADAGP
Rv2242|M.tuberculosis_H37Rv SGMNAVAGWRGAPRPVLARELLPERALMGDASAIVALHTDVMRPLADAGP
MLBr_01652|M.leprae_Br4923 SGMNAVAGWSGAPRPVQARELLPERALMGDASAIVALHTDVMLPLADAGP
MAV_2195|M.avium_104 SGMNAVGGWRGAPRPVLARELLPERALMGDASAIVALHTDVMGPLADAGP
MAB_1880c|M.abscessus_ATCC_199 SGMDAVSGWRGAPRPVSSRELLPERALLGDKAAIAALNTEVMRPLADAGP
:**::*.** .*.*** :*********:** * .**.::** **:****
Mflv_2780|M.gilvum_PYR-GCK ALMDTLDAYLDSGGAIEACARKLFIHPNTVRYRLKRITDFTGRDPTVPRD
Mvan_3753|M.vanbaalenii_PYR-1 ALMETLDAYLDSGGAIEACARKLFVHPNTVRYRLKRIADFTGRDPTVPRD
MSMEG_4324|M.smegmatis_MC2_155 ALTETLDAFLDSGGAIEACARKLFVHPNTVRYRLRRIADFTGRDPAVPRD
TH_1338|M.thermoresistible__bu TLTETLDAFLESGGAIEACARRLFVHPNTVRYRLRRIAEITGRDPAVPRD
MMAR_3335|M.marinum_M TLIETLDAYLDCGGAIEACARKLFVHPNTIRYRLKRITDFTGRDPTQPRD
MUL_1307|M.ulcerans_Agy99 TLIETLDAYLDCGGAIEACARKLFVHPNTIRYRLKRITDFTGRDPTQPRD
Mb2266|M.bovis_AF2122/97 TLIETLDAYLDCGGAIEACARKLFVHPNTVRYRLKRITDFTGRDPTQPRD
Rv2242|M.tuberculosis_H37Rv TLIETLDAYLDCGGAIEACARKLFVHPNTVRYRLKRITDFTGRDPTQPRD
MLBr_01652|M.leprae_Br4923 TLIETLDAYLDCGGAIEACARKLFVHPNTVRYRLKRITDFTGHDPTLPRD
MAV_2195|M.avium_104 TLIETLDAFLDSGGAIEACARKLFVHPNTVRYRLKRITDFTGRDPMQPRD
MAB_1880c|M.abscessus_ATCC_199 ALTETLDAYLDSGGAIEACARALFVHPNTVRYRLKRITDFTGRDPTSPRD
:* :****:*:.********* **:****:****:**:::**:** ***
Mflv_2780|M.gilvum_PYR-GCK AYVLRVASSLGRLTRQASQSPPLSARSGPRGGVASVTNPGTSP-
Mvan_3753|M.vanbaalenii_PYR-1 AYVLRVASSVGRLARQAHLSAAPAAASAQAIGVASVTSPENLGT
MSMEG_4324|M.smegmatis_MC2_155 AYVLRVASTVGRLSKHAYRASTINSAVSVVPTIRPATSAGSRGT
TH_1338|M.thermoresistible__bu AYVLRVAVSVSRLTRQSYQSSTVNPDLGSTAGWRGQAAGGHRAM
MMAR_3335|M.marinum_M AYVLRVAATVGQLNYPTPPSGAANNTITPVPLPVRRGTEGP---
MUL_1307|M.ulcerans_Agy99 AYVLRVAATVGQLNYPTPPSGAANNTITPVPLPVRRGTEGP---
Mb2266|M.bovis_AF2122/97 AYVLRVAATVGQLNYPTPH-------------------------
Rv2242|M.tuberculosis_H37Rv AYVLRVAATVGQLNYPTPH-------------------------
MLBr_01652|M.leprae_Br4923 AYVLRVAATVGKLNYPTHH-------------------------
MAV_2195|M.avium_104 AYVLRVAATVGQLNYPTHPPSAAGAAMPAVPLPVNGAARGQSGG
MAB_1880c|M.abscessus_ATCC_199 AYVLRVAATVGRLAQDHADAFTPEPGVTPVTINVIKT-------
******* ::.:*