For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. abscessus ATCC 19977 MAB_1391 (-)

annotation: putative transcriptional regulator
coordinates: 1387255 - 1388409
length: 384

MTASLSDRFMRRLPETARRAVDCFAAEVPYYGMLPREVLDGEITEFTKQHFRIFARVMLESRAPTDDEFA
VSILAASRRAQEDIPLPAVLAVYNVAARVGIETLRELATPDEVDEVLAVSVQLQRYLQLMLPAVTAAYLE
ERQGVYGAAADARRDLFEALVKGMPWEEAAERASVTLALSYHVLFLYMPEPATNTVVARRRAHRVQDIVD
EYAREPVLAALDGRGGTILLPAVGKVESLLPLFSEVAGGPVTIGLSEAADPAEIAAAADEARELALLALR
LGRAPGAYRLSDLLLEYQITRPGRARDLLAATVQPLAAHPHLQQALSAYLQHEHGRQLAAKSLHVHPNTL
DYRLRRVAELTGLDPAQPSAARTLAAALLAVKAR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_1391--100% (384)putative transcriptional regulator
M. abscessus ATCC 19977MAB_1880c-7e-1228.57% (287) hypothetical protein MAB_1880c
M. abscessus ATCC 19977MAB_0912-9e-0923.87% (377) hypothetical protein MAB_0912

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2266-2e-1328.06% (278) hypothetical protein Mb2266
M. gilvum PYR-GCKMflv_2780-3e-1429.20% (274) hypothetical protein Mflv_2780
M. tuberculosis H37RvRv2242-2e-1328.06% (278) hypothetical protein Rv2242
M. leprae Br4923MLBr_01652-6e-1327.96% (279) hypothetical protein MLBr_01652
M. marinum MMMAR_3335-3e-1326.47% (272) hypothetical protein MMAR_3335
M. avium 104MAV_2195-4e-1228.37% (282) hypothetical protein MAV_2195
M. smegmatis MC2 155MSMEG_4324-5e-1530.59% (304) hypothetical protein MSMEG_4324
M. thermoresistible (build 8)TH_1338-1e-1430.43% (276) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_1307-2e-1226.10% (272) hypothetical protein MUL_1307
M. vanbaalenii PYR-1Mvan_3753-2e-1430.91% (275) hypothetical protein Mvan_3753

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_3335|M.marinum_M               MNDN-QFS-AIARLGSARSPLELLETVPDSLLRRLKQYSGRLATEAVSAM
MUL_1307|M.ulcerans_Agy99           MNNN-QFS-AIARLGSARSPLELLETVPDSLLRRLKQYSGRLATEAVSAM
Mb2266|M.bovis_AF2122/97            MNDN-QLA-PVARP---RSPLELLDTVPDSLLRRLKQYSGRLATEAVSAM
Rv2242|M.tuberculosis_H37Rv         MNDN-QLA-PVARP---RSPLELLDTVPDSLLRRLKQYSGRLATEAVSAM
MLBr_01652|M.leprae_Br4923          MNHN-HFV-PAPPR---RLPLELLDTVPDSLLRRLKQYSGRLATEAVTAM
MAV_2195|M.avium_104                MNDN-PFAGPFAKHP--RSPLETLDTVPESVLRRLKQYSGRLATEAVSVM
Mflv_2780|M.gilvum_PYR-GCK          MPDNNRFVPPNSTV-------EVLGNVPDSTLRRLKQYSGRLATEAVHAM
Mvan_3753|M.vanbaalenii_PYR-1       MTDN-RFIPPRSTV-------EVLENVPESTLRRLKQYSGRLATQAVHAM
MSMEG_4324|M.smegmatis_MC2_155      MPDN-RFVPPKSTV-------EVLEAVPDSLLRRLKQYSGRLATEAVHAM
TH_1338|M.thermoresistible__bu      VPDN-RFVPPQSTL-------EVLESVPESVLRRLKQYSGRLATEAVHTM
MAB_1391|M.abscessus_ATCC_1997      ----------------------MTASLSDRFMRRLPET----ARRAVDCF
                                                              :.:  :*** :     * .**  :

MMAR_3335|M.marinum_M               QERLPFFADLEASQR-ASVALVVQTAVVNFAEWMQNPRS-DVSYTAQAFE
MUL_1307|M.ulcerans_Agy99           QERLPFFADLEASQR-ASVALVVQTAVVNFAEWMQNPRS-DVSYTAQAFE
Mb2266|M.bovis_AF2122/97            QERLPFFADLEASQR-ASVALVVQTAVVNFVEWMHDPHS-DVGYTAQAFE
Rv2242|M.tuberculosis_H37Rv         QERLPFFADLEASQR-ASVALVVQTAVVNFVEWMHDPHS-DVGYTAQAFE
MLBr_01652|M.leprae_Br4923          QERLPFFADLEASQR-ASVTLVVQTAVVNFVQWMQNPHS-DVSYTAQAFE
MAV_2195|M.avium_104                QDRLPFFADLEASQR-ASVSLVVQTAVVNFAEWMQDPKS-NVRHTAQAFE
Mflv_2780|M.gilvum_PYR-GCK          EERLPFFADMEASQR-ASVQLVVQTAVVNFVEWMRDPQS-DVSYTAQAFE
Mvan_3753|M.vanbaalenii_PYR-1       EERLPFFAELDASQR-ASVQLVVQTAVVNFAEWMRDPRS-NVSYTAQAFE
MSMEG_4324|M.smegmatis_MC2_155      EQRLPFFAELDASQR-ASVQLVVQTAVVNFVEWMRNPES-NVGYTAQAFE
TH_1338|M.thermoresistible__bu      EERLPFFADLEASQR-ASVHLVVQTAVVNFVEWMRDPRS-NVTYTMQAFE
MAB_1391|M.abscessus_ATCC_1997      AAEVPYYGMLPREVLDGEITEFTKQHFRIFARVMLESRAPTDDEFAVSIL
                                      .:*::. :  .   ..:  ..:  .  *.. * :..:        :: 

MMAR_3335|M.marinum_M               LVPQDLTRRIALRHTVDMVRVTMEFFEEVVPLLAR--SEEQLTALTVGIL
MUL_1307|M.ulcerans_Agy99           LVPQDLTRRIALRHTVDMVRVTMEFFEEVVPLLAR--SEEQLTALTVGIL
Mb2266|M.bovis_AF2122/97            LVPQDLTRRIALRQTVDMVRVTMEFFEEVVPLLAR--SEEQLTALTVGIL
Rv2242|M.tuberculosis_H37Rv         LVPQDLTRRIALRQTVDMVRVTMEFFEEVVPLLAR--SEEQLTALTVGIL
MLBr_01652|M.leprae_Br4923          LVPQDLARRIALRHTVDMVRVTMEFFEEVVPLLAR--SEEQLTALTVGIL
MAV_2195|M.avium_104                LVPQDLARRIALRHSVEMVRVTMEFFEEVVPLLAR--SEEQLTALTVGVL
Mflv_2780|M.gilvum_PYR-GCK          VVPQDLRRRIALRQSVEMVRTTMEYFEEVVPLLAR--SEDQLTALTAGIL
Mvan_3753|M.vanbaalenii_PYR-1       VVPQDLRRRIALRQSVEMVRVTMEFFEEVVPLLAR--SEDQLAAMTAGIL
MSMEG_4324|M.smegmatis_MC2_155      VVPQDLRRRVALRQSVEMVRTSMEFFEEAVPLLAR--SEEQLTALTAGIL
TH_1338|M.thermoresistible__bu      VVPQDLTRRIALRQTVEMVRTTMEFFEQVVPLLAR--SEEQVTALTAGIL
MAB_1391|M.abscessus_ATCC_1997      AASRRAQEDIPLPAVLAVYNVAARVGIETLRELATPDEVDEVLAVSVQLQ
                                     ..:   . :.*   : : ..: .   :.:  **   . ::: *::. : 

MMAR_3335|M.marinum_M               KYSRDLAFTAASAYADAAEARGTWDSRMEASVVDAVVRGDTGPELLSRAA
MUL_1307|M.ulcerans_Agy99           KYSRDLAFTAASAYADAAEARGTWDSRMEASVVDAVVRGDTGPELLSRAA
Mb2266|M.bovis_AF2122/97            KYSRDLAFTAATAYADAAEARGTWDSRMEASVVDAVVRGDTGPELLSRAA
Rv2242|M.tuberculosis_H37Rv         KYSRDLAFTAATAYADAAEARGTWDSRMEASVVDAVVRGDTGPELLSRAA
MLBr_01652|M.leprae_Br4923          KYSRDLAFTAATAYADAAEARGTWDSRMEASVVDAVVRGDTGPELLSRAA
MAV_2195|M.avium_104                KYSRDLAFTAATAYADAAEARGTWDSRMEASVVDAVVRGDTGPELLSRAA
Mflv_2780|M.gilvum_PYR-GCK          RYSRDLAFAAASAYADQAEARGAWDTRIESNLVDAVVRGDIGPDLQSQAA
Mvan_3753|M.vanbaalenii_PYR-1       RYSRDLAFAAATAYADQAEARGAWDTRMEANLVDAVVRGGTRPELQSQAA
MSMEG_4324|M.smegmatis_MC2_155      RYSRDLAFAAASAYADQAEARGAWDIRMEANIVDAVVRGDTGPELQSQAA
TH_1338|M.thermoresistible__bu      RYSRDLAFAAATAYADAAEARGAWDTRMEANVVDAVVRGAVGPELQSQAA
MAB_1391|M.abscessus_ATCC_1997      RYLQLMLPAVTAAYLEERQGVYGAAADARRDLFEALVKGMPWEEAAERAS
                                    :* : :  :.::** :  :.        . .:.:*:*:*    :  .:*:

MMAR_3335|M.marinum_M               ALNWDTTAPATVVVGTPASARDGS--DG-SERAIQDVRDAAAQHGRAALT
MUL_1307|M.ulcerans_Agy99           ALNWDTTAPATVVVGTPASARDGS--DG-SERAIQDVRDAAAQHGRAALT
Mb2266|M.bovis_AF2122/97            ALNWDTTAPATVLVGTPAPGPNGSNSDGDSERASQDVRDTAARHGRAALT
Rv2242|M.tuberculosis_H37Rv         ALNWDTTAPATVLVGTPAPGPNGSNSDGDSERASQDVRDTAARHGRAALT
MLBr_01652|M.leprae_Br4923          ALNWDTTAPATVVVGTPTPNHDGPNGQVSSERASQEVREIAARHGRAALT
MAV_2195|M.avium_104                ALNWDTTAPATVVVGTPAPGRDGSTGPGDSERASQHVRDIAAQHGRAALT
Mflv_2780|M.gilvum_PYR-GCK          ALNWDATAPATVIVGTPRPD--------RTEFVVDDVHDVVKRHGRAALS
Mvan_3753|M.vanbaalenii_PYR-1       ALNWDATAPATVIVGMPRPD--------RAEFAGDDVHEVADRNGRTALS
MSMEG_4324|M.smegmatis_MC2_155      ALNWDATAPATVIVGLPRAD--------RIEMARDDVHAVVRRNDRAALS
TH_1338|M.thermoresistible__bu      ALNWDATAPATVVVGLPRPD--------RLEVVSQDVHHVANRHGRTALS
MAB_1391|M.abscessus_ATCC_1997      VT--LALSYHVLFLYMPEPATNTVVARRRAHRVQDIVDEYAREPVLAALD
                                    .    : :  .:.:  * .           . . : *   . .   :** 

MMAR_3335|M.marinum_M               DVHGTWLVAIVSGHLSPTDKVFKDLLEAFSDGPVVIGPTAPMLTAAYHSA
MUL_1307|M.ulcerans_Agy99           DVHGTWLVAIVSGHLSPTDKVFKDLLEAFSDGPVVIGPTAPMLTAAYHSA
Mb2266|M.bovis_AF2122/97            DVHGTWLVAIVSGQLSPTEKFLKDLLAAFADAPVVIGPTAPMLTAAHRSA
Rv2242|M.tuberculosis_H37Rv         DVHGTWLVAIVSGQLSPTEKFLKDLLAAFADAPVVIGPTAPMLTAAHRSA
MLBr_01652|M.leprae_Br4923          DVHGTWLVAIISGQLAPTDKFFSDLLHAFSDGPVVIGPTAPMLTAAYHSA
MAV_2195|M.avium_104                DVHGTWLVAIVSGQLSPTDKFLGDLLEAFSDGPVVVGPTAPMLTAAYHSA
Mflv_2780|M.gilvum_PYR-GCK          DVHGTWLVAIVSGNLSPTDRFLAELMSVFADGPVVIGPTAATLGGAHRSA
Mvan_3753|M.vanbaalenii_PYR-1       DVHGTWLVAIISGGLSPTDRFLSELMTVFADGPVVIGPTAPTLGAAHRSA
MSMEG_4324|M.smegmatis_MC2_155      DVHGTWLVTIVSGPLSATDRFLADLMSVFADGPVVIGPTTPTLTAAHRSA
TH_1338|M.thermoresistible__bu      DVHGTWLVTIVSGALSPTDRFLTDLLDVFADGPVVLGPTAPTLSAAYRSA
MAB_1391|M.abscessus_ATCC_1997      GRGGTILLPAVG-----KVESLLPLFSEVAGGPVTIGLSEAADPAEIAAA
                                    .  ** *:. :.     . . :  *:  .:..**.:* : .   .   :*

MMAR_3335|M.marinum_M               SEAISGMNAVAGWRG-APRPVLARELLPERALMGDASAIVALHTDVMRPL
MUL_1307|M.ulcerans_Agy99           SEAISGMNAVAGWRG-ASRPVLARELLPERALMGDASAIVALHTDVMRPL
Mb2266|M.bovis_AF2122/97            SEAISGMNAVAGWRG-APRPVLARELLPERALMGDASAIVALHTDVMRPL
Rv2242|M.tuberculosis_H37Rv         SEAISGMNAVAGWRG-APRPVLARELLPERALMGDASAIVALHTDVMRPL
MLBr_01652|M.leprae_Br4923          SEAVSGMNAVAGWSG-APRPVQARELLPERALMGDASAIVALHTDVMLPL
MAV_2195|M.avium_104                SEAISGMNAVGGWRG-APRPVLARELLPERALMGDASAIVALHTDVMGPL
Mflv_2780|M.gilvum_PYR-GCK          TEAVAGMNSVAGWPG-APRPVAARELLPERALLGDVTAATALEAEVMRPL
Mvan_3753|M.vanbaalenii_PYR-1       TEAIAGMNAVAGWAG-APRPVSARELLPERALLGDATAGAALEAEVMRPL
MSMEG_4324|M.smegmatis_MC2_155      TEAISGMNAVAGWPS-APRPVSARELLPERALLGDADAVTALETEVMRPL
TH_1338|M.thermoresistible__bu      TEAIAGMNAVAGWSG-APRPVPARELLPERALLGDQTAIAALESEVMRPL
MAB_1391|M.abscessus_ATCC_1997      ADEARELALLALRLGRAPGAYRLSDLLLEYQITRPGRARDLLAATVQP--
                                    ::    :  :.   . *. .    :** *  :     *   * : *    

MMAR_3335|M.marinum_M               ADAGPTLIETLDAYLDCGGAIEACARKLFVHPNTIRYRLKRITDFTGRDP
MUL_1307|M.ulcerans_Agy99           ADAGPTLIETLDAYLDCGGAIEACARKLFVHPNTIRYRLKRITDFTGRDP
Mb2266|M.bovis_AF2122/97            ADAGPTLIETLDAYLDCGGAIEACARKLFVHPNTVRYRLKRITDFTGRDP
Rv2242|M.tuberculosis_H37Rv         ADAGPTLIETLDAYLDCGGAIEACARKLFVHPNTVRYRLKRITDFTGRDP
MLBr_01652|M.leprae_Br4923          ADAGPTLIETLDAYLDCGGAIEACARKLFVHPNTVRYRLKRITDFTGHDP
MAV_2195|M.avium_104                ADAGPTLIETLDAFLDSGGAIEACARKLFVHPNTVRYRLKRITDFTGRDP
Mflv_2780|M.gilvum_PYR-GCK          ADAGPALMDTLDAYLDSGGAIEACARKLFIHPNTVRYRLKRITDFTGRDP
Mvan_3753|M.vanbaalenii_PYR-1       SDAGPALMETLDAYLDSGGAIEACARKLFVHPNTVRYRLKRIADFTGRDP
MSMEG_4324|M.smegmatis_MC2_155      ADAGPALTETLDAFLDSGGAIEACARKLFVHPNTVRYRLRRIADFTGRDP
TH_1338|M.thermoresistible__bu      ADAGPTLTETLDAFLESGGAIEACARRLFVHPNTVRYRLRRIAEITGRDP
MAB_1391|M.abscessus_ATCC_1997      LAAHPHLQQALSAYLQHEHGRQLAAKSLHVHPNTLDYRLRRVAELTGLDP
                                      * * * ::*.*:*:   . : .*: *.:****: ***:*::::** **

MMAR_3335|M.marinum_M               TQPRDAYVLRVAATVGQLNYPTPPSGAANNTITPVPLPVRRGTEGP---
MUL_1307|M.ulcerans_Agy99           TQPRDAYVLRVAATVGQLNYPTPPSGAANNTITPVPLPVRRGTEGP---
Mb2266|M.bovis_AF2122/97            TQPRDAYVLRVAATVGQLNYPTPH-------------------------
Rv2242|M.tuberculosis_H37Rv         TQPRDAYVLRVAATVGQLNYPTPH-------------------------
MLBr_01652|M.leprae_Br4923          TLPRDAYVLRVAATVGKLNYPTHH-------------------------
MAV_2195|M.avium_104                MQPRDAYVLRVAATVGQLNYPTHPPSAAGAAMPAVPLPVNGAARGQSGG
Mflv_2780|M.gilvum_PYR-GCK          TVPRDAYVLRVASSLGRLTRQASQSPPLSARSGPRGGVASVTNPGTSP-
Mvan_3753|M.vanbaalenii_PYR-1       TVPRDAYVLRVASSVGRLARQAHLSAAPAAASAQAIGVASVTSPENLGT
MSMEG_4324|M.smegmatis_MC2_155      AVPRDAYVLRVASTVGRLSKHAYRASTINSAVSVVPTIRPATSAGSRGT
TH_1338|M.thermoresistible__bu      AVPRDAYVLRVAVSVSRLTRQSYQSSTVNPDLGSTAGWRGQAAGGHRAM
MAB_1391|M.abscessus_ATCC_1997      AQPSAARTLAAALLAVKAR------------------------------
                                      *  * .* .*    :