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EIKDAVAVVTGGASGLGLATTKRLLDRGASVVVMDLRGEEAVKELDARAKFVETNVTDPEQVAAALDAAE EMGPLRIDVNCAGIGNAAKTLSKDGPFPLDAFKKVVEVNLIGTFNVIRLAAERIAKQEPINGERGVIINT ASVAAFEGQIGQAAYSASKGGVVGMTLPIARDLSRELIRVCTIAPGLFKTPLLGSLPEEAQASLGKQVPH PARLGDPDEYGALAVHIVENPMLNGETIRLDGAIRMAPR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4577 | - | - | 100% (250) | short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_2027 | - | 2e-60 | 50.19% (257) | short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_4251 | - | 7e-59 | 49.22% (256) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1176 | - | 1e-104 | 74.40% (250) | short-chain type dehydrogenase/reductase |
| M. gilvum PYR-GCK | Mflv_2127 | - | 1e-128 | 92.40% (250) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1144 | - | 1e-104 | 74.40% (250) | short-chain type dehydrogenase/reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 6e-22 | 32.23% (242) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0368 | - | 2e-68 | 52.87% (261) | Short-chain dehydrogenase/reductas |
| M. marinum M | MMAR_4307 | - | 1e-105 | 76.68% (253) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_1285 | - | 1e-119 | 87.40% (254) | 3-hydroxyacyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5183 | - | 1e-115 | 85.38% (253) | 3-hydroxyacyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_1987 | - | 1e-120 | 87.25% (251) | 3-Hydroxyacyl-CoA dehydrogenase |
| M. ulcerans Agy99 | MUL_0987 | - | 1e-105 | 76.28% (253) | short-chain type dehydrogenase/reductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1176|M.bovis_AF2122/97 ----------------MKTKDAVAVVTGGASGLGLATTKRLLDAGAQVVV
Rv1144|M.tuberculosis_H37Rv ----------------MKTKDAVAVVTGGASGLGLATTKRLLDAGAQVVV
MMAR_4307|M.marinum_M ----------------MEIRDAVAVVTGGASGLGLATTKRLLDAGAQVVV
MUL_0987|M.ulcerans_Agy99 ----------------MEIRDAVAVVTGGASGLGLATTKRLLDAGAQVVV
Mvan_4577|M.vanbaalenii_PYR-1 ----------------MEIKDAVAVVTGGASGLGLATTKRLLDRGASVVV
Mflv_2127|M.gilvum_PYR-GCK ----------------MEIKDAAAVVTGGASGLGLATTKRLLDRGASVVV
MAV_1285|M.avium_104 ----------------MEIKDAVAVVTGGASGLGLATTKRLLDRGAQVVV
TH_1987|M.thermoresistible__bu ----------------VEIKDSVAVVTGGASGLGLATTKRLLDRGAQVVV
MSMEG_5183|M.smegmatis_MC2_155 ----------------MEIKDAVAVVTGGASGLGLATTKRLLDAGAQVVV
MAB_0368|M.abscessus_ATCC_1997 ----------------MDINGVSAIVTGGASGLGAATARLLAAQGAKVVI
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
. :**** *:* *.:: * * *.:
Mb1176|M.bovis_AF2122/97 VDLR---GDDVVGGLGDRARFAQADVTDEAAVSNALELADSLG-PVRVVV
Rv1144|M.tuberculosis_H37Rv VDLR---GDDVVGGLGDRARFAQADVTDEAAVSNALELADSLG-PVRVVV
MMAR_4307|M.marinum_M LDIR---GEDVVADLGDRARFAAADVTDEAAVASALDLAETMG-TLRIVV
MUL_0987|M.ulcerans_Agy99 LDIR---GEDVVADLGDRARFAAADVTDEAAVASALDLAETMG-TLRIVV
Mvan_4577|M.vanbaalenii_PYR-1 MDLR---GEEAVKELDARAKFVETNVTDPEQVAAALDAAEEMG-PLRIDV
Mflv_2127|M.gilvum_PYR-GCK IDLK---GEDVVAELGPRAKFVEANVTDPEQVAAALDAAEEFG-PLRINV
MAV_1285|M.avium_104 IDLR---GEDAVRELGDRARFVQADVTDEAAVGKALDTAESMG-PLRINV
TH_1987|M.thermoresistible__bu LDLK---GEDAVKALGDRARFVETNVTDEAAVAKALDVAEEMG-PVRINV
MSMEG_5183|M.smegmatis_MC2_155 IDLK---GEEVVAELGDRAKFVATDVTDEAGVTEALNVAESLG-PVRINV
MAB_0368|M.abscessus_ATCC_1997 ADVQDEKGEALAKELGG--AFVHTDVTSEADGIAAVDAAKELG-PVRVLI
MLBr_01807|M.leprae_Br4923 THRA--------SVVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVLV
. : . :**. *.. .. .:.: :
Mb1176|M.bovis_AF2122/97 NCAGTGNAIRVLSRDGVFP----LAAFRKIVDINLVGTFNVLRLGAERIA
Rv1144|M.tuberculosis_H37Rv NCAGTGNAIRVLSRDGVFP----LAAFRKIVDINLVGTFNVLRLGAERIA
MMAR_4307|M.marinum_M NCAGTGNAIRVLSRDGVFP----LAAFRKIVDINLVGSFNVLRLAAERIA
MUL_0987|M.ulcerans_Agy99 NCAGTGNAIRVLSRDGVFS----LAAFRKIVDINLVGSFNVLRLAAERIA
Mvan_4577|M.vanbaalenii_PYR-1 NCAGIGNAAKTLSKDGPFP----LDAFKKVVEVNLIGTFNVIRLAAERIA
Mflv_2127|M.gilvum_PYR-GCK NCAGIGNAIKTLSKDGPFP----LDGFTKVIQVNLIGTFNVLRLAAERMA
MAV_1285|M.avium_104 NCAGIGNAIKTLSKDGPFP----LDAFKKVVGVNLIGTFNVLRLAAERIA
TH_1987|M.thermoresistible__bu NCAGIGNAIKTLSKNGPFP----LDEFTKVIQVNLIGTFNVLRLAAERIA
MSMEG_5183|M.smegmatis_MC2_155 NCAGIGNAIKTLSKNGPFP----LDGFRKVVEVNLIGTFNVIRLSAERIA
MAB_0368|M.abscessus_ATCC_1997 NCAGVGWPGRTIGKDGQYASAHSLDIFSKVIGINLIGSFNLIRLAATAIS
MLBr_01807|M.leprae_Br4923 ANAGITSDMLIMRMS--------EEQFQKVIDVNLTGVFRVAKLASRNMI
** : . * *:: :** * *.: :*.: :
Mb1176|M.bovis_AF2122/97 KTEPIG----EERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPIAR
Rv1144|M.tuberculosis_H37Rv KTEPIG----EERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPIAR
MMAR_4307|M.marinum_M KTEPVGP-NAEERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPIAR
MUL_0987|M.ulcerans_Agy99 KTEPVGP-NAEERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPIAR
Mvan_4577|M.vanbaalenii_PYR-1 KQEPING----ERGVIINTASVAAFEGQIGQAAYSASKGGVVGMTLPIAR
Mflv_2127|M.gilvum_PYR-GCK KQEPING----ERGVIINTASVAAFEGQIGQAAYSASKGGVVGMTLPIAR
MAV_1285|M.avium_104 KTEPIGPGTSPERGVIINTASVAAFEGQIGQAAYSASKGGVVGMTLPIAR
TH_1987|M.thermoresistible__bu KTEPLKG---EERGVIINTASVAAFEGQIGQAAYSASKGGVVGMTLPIAR
MSMEG_5183|M.smegmatis_MC2_155 KTEPIGP-NGEERGVIINTASVAAFDGQIGQAAYSASKGGVVGMTLPIAR
MAB_0368|M.abscessus_ATCC_1997 QEEPVDEFG--ERGAIVNTASVAAFDGQIGQAAYSASKGGIVGMTLPIAR
MLBr_01807|M.leprae_Br4923 KQ---------RFGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLAR
: . * : .**..:.* *** *:***.*::**: .:**
Mb1176|M.bovis_AF2122/97 DLASKLIRVVTIAPGLFDTPLLAS--LPAEAKASLGQQVPHPSRLGNPDE
Rv1144|M.tuberculosis_H37Rv DLASKLIRVVTIAPGLFDTPLLAS--LPAEAKASLGQQVPHPSRLGNPDE
MMAR_4307|M.marinum_M DLASHRIRVMTIAPGLFDTPLLAS--LPEEARASLGKQVPHPSRLGSPDE
MUL_0987|M.ulcerans_Agy99 DLASHRIRVMTIAPGLFDTPLLAS--LPEEARASLGKQVPHPSRLGNPDE
Mvan_4577|M.vanbaalenii_PYR-1 DLSRELIRVCTIAPGLFKTPLLGS--LPEEAQASLGKQVPHPARLGDPDE
Mflv_2127|M.gilvum_PYR-GCK DLSREFIRVCTIAPGLFKTPLLGS--LPEEAQASLGKQVPHPARLGDPDE
MAV_1285|M.avium_104 DLARELIRVVTIAPGLFKTPLLGS--LPEEAQASLGKQVPHPARLGDPDE
TH_1987|M.thermoresistible__bu DLARELIRVVTIAPGLFKTPLLGS--LPEEAQKSLGQQVPHPARLGDPDE
MSMEG_5183|M.smegmatis_MC2_155 DLSRELIRVVTIAPGLFKTPLLGS--LPEEAQKSLGAQVPHPARLGDPDE
MAB_0368|M.abscessus_ATCC_1997 DLSVVGIRVNTIAPGLIDTPIYGEGESAQQFKDRLAPNVLYPQRLGNPEE
MLBr_01807|M.leprae_Br4923 ELGSRSITANVVAPGFIDTEMTRA--MDSKYQEAALQAIPLGRIGAVEEI
:*. * . .:***::.* : : : : . :
Mb1176|M.bovis_AF2122/97 YGALVLHIIENP-MLNGEVIRLDGAIRMAPR
Rv1144|M.tuberculosis_H37Rv YGALVLHIIENP-MLNGEVIRLDGAIRMAPR
MMAR_4307|M.marinum_M YGALAVHIIENP-MLNGEVIRLDGAIRMAPR
MUL_0987|M.ulcerans_Agy99 YGALAVHIIENP-MLNGEVIRLDGAIRMAPR
Mvan_4577|M.vanbaalenii_PYR-1 YGALAVHIVENP-MLNGETIRLDGAIRMAPR
Mflv_2127|M.gilvum_PYR-GCK YGALAVHIVENP-MLNGETIRLDGAIRMAPR
MAV_1285|M.avium_104 YGALAVHIVENP-MLNGEVIRLDGAIRMAPR
TH_1987|M.thermoresistible__bu YGALAVHIVENP-MLNGEVIRLDGAIRMAPR
MSMEG_5183|M.smegmatis_MC2_155 YGALAQHIIENP-MLNGEVIRLDGAIRMAPR
MAB_0368|M.abscessus_ATCC_1997 FASLALELVTNS-YMNAETIRIDGGARLQPK
MLBr_01807|M.leprae_Br4923 AGAVSFLASEDAGYISGAVIPVDGGLGMGH-
.:: :. :.. .* :**. :