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VSELNGDTEPEVLVEQRDRILIITINRPKAKNSVNAAVSRALADAMDRLDADAGLSVGILTGAGGSFCAG MDLKAFARGENVVVEGRGLGFTERPPAKPLIAAVEGYALAGGTELALATDLIVAARDSAFGIPEVKRGLA AGGGGLLRLPERIPYAIAMELALTGDNLSAERAHALGMVNVLAEPGAALDAAIALAEKITANGPLAVAAT KRIITESRGWSLDTRFAQQMKILFPIFTSNDAKEGAIAFAEKRPPRWTGT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1114 | echA1 | - | 100% (260) | enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_0972 | echA1_1 | 6e-57 | 44.74% (266) | enoyl-CoA hydratase, EchA1_1 |
| M. ulcerans Agy99 | MUL_4076 | echA19 | 7e-51 | 42.91% (268) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3545 | echA19 | 9e-50 | 42.86% (266) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_4354 | - | 3e-96 | 69.60% (250) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv0222 | echA1 | 1e-128 | 91.34% (254) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 6e-33 | 34.23% (260) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_4588c | - | 6e-91 | 68.27% (249) | enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_0465 | echA1 | 1e-143 | 99.62% (260) | enoyl-CoA hydratase EchA1 |
| M. avium 104 | MAV_4951 | - | 1e-122 | 86.51% (252) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_2227 | - | 2e-90 | 66.01% (253) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_3963 | - | 1e-111 | 79.22% (255) | PUTATIVE enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_1990 | - | 8e-93 | 66.80% (250) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_1114|M.ulcerans_Agy99 MSELN----GDTEPEVLVEQRDRILIITINRPKAKNSVNAAVSRALADAM
MMAR_0465|M.marinum_M MSELN----GDTEPEVLVEQRDRILIITINRPKAKNSVNAAVSRALADAM
Rv0222|M.tuberculosis_H37Rv MSSESDA--ANTEPEVLVEQRDRILIITINRPKAKNAVNAAVSRGLADAM
MAV_4951|M.avium_104 MRHVSTGNEEAGEPEVLVEQRDRILIITINRPKAKNAVNAAVANGLAAAV
TH_3963|M.thermoresistible__bu VTEQG-----SSDNPVLVEQRGRILIITINRPEAKNAVNLAVAQGLAAAM
Mflv_4354|M.gilvum_PYR-GCK ----------MSDEVLL-ERRDRVLIITINRPEARNAFNLAVAQGLADAM
Mvan_1990|M.vanbaalenii_PYR-1 ----------MADEVLL-ERRDRVLIITINRPEARNAFNLAVAQGLADAM
MSMEG_2227|M.smegmatis_MC2_155 ----------MSEEVVLRERRDRTLIITINRPEARNAFNLAVAKGLAEAV
MAB_4588c|M.abscessus_ATCC_199 -----------MADEVLIEQRDRVLLITINRPDARNAVNRAVSQGLAAAA
Mb3545|M.bovis_AF2122/97 ---------MESGPDALVERRGHTLIVTMNRPAARNALSTEMMRIMVQAW
MLBr_02402|M.leprae_Br4923 ----------MKYDTILVDGYQRVGIITLNRPQALNALNSQMMNEITNAA
* : : ::*:*** * *:.. : . :. *
MUL_1114|M.ulcerans_Agy99 DRLDADAGLSVGILTGAGGSFCAGMDLKAFAR---GENVVVEGRGLG---
MMAR_0465|M.marinum_M DRLDADAGLSVGILTGAGGSFCAGMDLKAFAR---GENVVVEGRGLG---
Rv0222|M.tuberculosis_H37Rv DQLDGDAGLSVAILTGGGGSFCAGMDLKAFAR---GENVVVEGRGLG---
MAV_4951|M.avium_104 DRLDSEPGLSVGVLTGAGGSFCAGMDLKAFAR---GELPIVEGRGMG---
TH_3963|M.thermoresistible__bu DRLDDDKGLSVGIVTGAGGSFSAGMDLKAFAR---GEFPVVEGRGLG---
Mflv_4354|M.gilvum_PYR-GCK DELDDTPELSVAIITGAGGNFCAGMDLKAFMA---GEVPAIEGRGIG---
Mvan_1990|M.vanbaalenii_PYR-1 DELDSSAELSVAIITGAGGNFCAGMDLKAFMA---GEVPAIEGRGIG---
MSMEG_2227|M.smegmatis_MC2_155 DELDDTQELSVGIITGAGGTFCAGMDLKGFAS---GELPHVPGRGIG---
MAB_4588c|M.abscessus_ATCC_199 DQLDSSADLSVAIITGAGGNFCAGMDLKAFVS---GEAVLSE-RGLG---
Mb3545|M.bovis_AF2122/97 DRVDNDPDIRCCILTGAGGYFCAGMDLKAATQKPPGDSFKDGSYDPSRID
MLBr_02402|M.leprae_Br4923 KELDIDPDVGAILITGSPKVFAAGADIKEMASLTFTDAFDADFFSAWG--
..:* : ::**. *.** *:* : .
MUL_1114|M.ulcerans_Agy99 --FTERPPAKPLIAAVEGYALAGGTELALATDLIVAARDSAFGIPEVKRG
MMAR_0465|M.marinum_M --FTERPPAKPLIAAVEGYALAGGTELALATDLIVAARDSAFGIPEVKRG
Rv0222|M.tuberculosis_H37Rv --FTERPPTKPLIAAVEGYALAGGTELALAADLIVAARDSAFGIPEVKRG
MAV_4951|M.avium_104 --FTERPPAKPLIAAVEGYALAGGTELALATDLIVASKDAAFGIPEVKRG
TH_3963|M.thermoresistible__bu --YTEKPPAKPLIAAVEGYALAGGTELALAADMIVASRESAFGIPEVKRG
Mflv_4354|M.gilvum_PYR-GCK --FTERPPRKPLIAAVEGYALAGGTEIVLATDLIVAAKNAKFGIPEVKRG
Mvan_1990|M.vanbaalenii_PYR-1 --FTERPPRKPVIAAVEGYALAGGTEIVLATDLIVAAKNAKFGIPEVKRG
MSMEG_2227|M.smegmatis_MC2_155 --FTEKPPRKPLIAAVEGYALAGGTEIVLATDLVVASRTAKFGIPEVKRG
MAB_4588c|M.abscessus_ATCC_199 --FTNVPPRKPIIAAVEGFALAGGTELVLSCDLVVAGRSAKFGIPEVKRG
Mb3545|M.bovis_AF2122/97 ALLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWS
MLBr_02402|M.leprae_Br4923 ---KLAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLG
. .*:**** * *:.** *: *: :*. : ** .* * .
MUL_1114|M.ulcerans_Agy99 LAAGGGGLLRLPERIPYAIAMELALTGDNLSAERAHALGMVNVLAEPGAA
MMAR_0465|M.marinum_M LVAGGGGLLRLPERIPYAIAMELALTGDNLSAERAHALGMVNVLAEPGAA
Rv0222|M.tuberculosis_H37Rv LVAGGGGLLRLPERIPYAIAMELALTGDNLPAERAHELGLVNVLAEPGTA
MAV_4951|M.avium_104 LVAGGGGLLRLPQRIPSAIAMELALTGDNLSAERAHALGMVNVLAEPGSA
TH_3963|M.thermoresistible__bu LVAGGGGLLRLPERIPYSIAMELALTGDILPAERAHDLGLVNALTEPGAA
Mflv_4354|M.gilvum_PYR-GCK LVAAGGGLLRLQKRIPYQKALELALTGDSFTAEEASAWGFVNVLTEPGGA
Mvan_1990|M.vanbaalenii_PYR-1 LVAAGGGLLRLQKRIPYQKALELALTGDSFTAEEASQWGFVNVLTEPGEA
MSMEG_2227|M.smegmatis_MC2_155 LVAAGGGLLRLPKRIPYQKALELALTGDNFTAEEAAAWGFVNKLTEPGEA
MAB_4588c|M.abscessus_ATCC_199 LVAGAGGLLRLPNRIPYQVAMELALTGESFTAEDAAKYGFINRLVDDGQA
Mb3545|M.bovis_AF2122/97 LYPMGGSAVRLVRQIPYTLACDLLLTGRHITAAEAKEMGLIGHVVPDGQA
MLBr_02402|M.leprae_Br4923 VLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDL
: . *. ** . * * :* *** : * * *::. :. .
MUL_1114|M.ulcerans_Agy99 LDAAIALAEKITANGPLAVAATKRIITESRGWSLDTRFAQQMKILFPIFT
MMAR_0465|M.marinum_M LDAAIALAEKITANGPLAVAATKRIITESRGWSLDTRFAQQMKILFPIFT
Rv0222|M.tuberculosis_H37Rv LDAAIALAEKITANGPLAVVATKRIITESRGWSPDTMFAEQMKILVPVFT
MAV_4951|M.avium_104 LDEAIALAEKIAANGPLAVAATKRIIVESRGWSPETMFAEQNKLLAPVFS
TH_3963|M.thermoresistible__bu LDGAIELAERIAANGPLAVATTKRIIIESKKWTPDTMFAEQGKLMAPVFS
Mflv_4354|M.gilvum_PYR-GCK LDGALALAERITANGPLAVAATKEVIAKSADWTEAEMWKKQGEIVFPVFS
Mvan_1990|M.vanbaalenii_PYR-1 LNGALALAERITANGPLAVAVTKEVIVKSADWTEAEMWKKQGELVMSVFS
MSMEG_2227|M.smegmatis_MC2_155 LAGALELAERITANGPLAVAVTKEVIVKSAEWSEAEMWKKQGELIGPVFS
MAB_4588c|M.abscessus_ATCC_199 LDTALELAAKITANGPLAVAATKRIIIESASWAPEEAFAKQGEILMPIFV
Mb3545|M.bovis_AF2122/97 LTKALELADAISANGPLAVQAILRSIRETECMPENEAFKIDTQIGIKVFL
MLBr_02402|M.leprae_Br4923 LPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHSTFV
* * :* *: . *. . : .: . : .: *
MUL_1114|M.ulcerans_Agy99 SNDAKEGAIAFAEKRPPRWTGT
MMAR_0465|M.marinum_M SNDAKEGAIAFAEKRPPRWTGT
Rv0222|M.tuberculosis_H37Rv SNDAKEGAIAFAERRRPRWTGT
MAV_4951|M.avium_104 SNDAKEGAIAFAEKRPPKWTGT
TH_3963|M.thermoresistible__bu SNDAKEGAIAFAEKRAPNWTGT
Mflv_4354|M.gilvum_PYR-GCK SKDAMEGATAFAEKRKPNWTGT
Mvan_1990|M.vanbaalenii_PYR-1 SKDAMEGATAFAEKRKPNWTGS
MSMEG_2227|M.smegmatis_MC2_155 SKDAIEGATAFAEKRKPNWTGS
MAB_4588c|M.abscessus_ATCC_199 SEDAKEGAKAFAEKRAPVWQGK
Mb3545|M.bovis_AF2122/97 SDDAKEGPRAFAEKRAPNFQNR
MLBr_02402|M.leprae_Br4923 TDDQSEGMAAFIEKRAPQFTHR
:.* ** ** *:* * :