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VHSWGGEKRLPRSAVVGALVAAVLAMVVHDHLVPFDVRFFGLTQNGYDLDTYRAAVRGLWDGKRLYEAPA LNQAWFVYPPFATLVLAPLAWASFEVAKWMLLILSLSALALIAWRILRLAGVRADSRLGLASAALAAIVV DVEPVQATLWWGQINILLMAVVLLDLLGPAQSRWRGVGLGLAAGIKLTPLIFLPYLLCTRQWRAATHALG TMAATVALTWPLLPRDSEWFWSHLGDTAHISRIDHLANQTINGFLARYFFPQPRPEWLWIALSLLVLAAG LAVAVWAHRRGEHALALILVGLTGCAVSPFSWAAHWVWFAPAIVWLVAKACTTQGPWSQGWIYRAAGLLA LVFMWTLHRPGRGHTTIYFSGVYWNFLDLRPFWAGQLVSGWYPLVFLCFTIATASWLRLSTGGCAEPDEL ATLTADIEDYPPEIFDEELAVRA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0096 | - | - | 100% (443) | hypothetical protein MAB_0096 |
| M. abscessus ATCC 19977 | MAB_0281 | - | 2e-75 | 37.78% (405) | hypothetical protein MAB_0281 |
| M. abscessus ATCC 19977 | MAB_1985 | - | 3e-44 | 31.67% (420) | hypothetical protein MAB_1985 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2203 | - | 2e-42 | 37.86% (309) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_0993 | - | 3e-63 | 42.63% (319) | hypothetical protein Mflv_0993 |
| M. tuberculosis H37Rv | Rv2181 | - | 2e-42 | 37.86% (309) | integral membrane protein |
| M. leprae Br4923 | MLBr_00893 | - | 4e-36 | 33.44% (305) | hypothetical protein MLBr_00893 |
| M. marinum M | MMAR_3225 | - | 3e-36 | 35.90% (312) | hypothetical protein MMAR_3225 |
| M. avium 104 | MAV_2312 | - | 6e-41 | 36.94% (333) | hypothetical protein MAV_2312 |
| M. smegmatis MC2 155 | MSMEG_4247 | - | 2e-35 | 32.05% (415) | integral membrane protein |
| M. thermoresistible (build 8) | TH_1105 | - | 2e-37 | 33.82% (346) | Probable conserved integral membrane protein |
| M. ulcerans Agy99 | MUL_3536 | - | 1e-35 | 35.58% (312) | hypothetical protein MUL_3536 |
| M. vanbaalenii PYR-1 | Mvan_3543 | - | 6e-35 | 34.22% (374) | putative integral membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2203|M.bovis_AF2122/97 ---MSAWRAPEVGSRLGRRVLWCLLWLLAGVALGYVAWRLFGHTPYRIDI
Rv2181|M.tuberculosis_H37Rv ---MSAWRAPEVGSRLGRRVLWCLLWLLAGVALGYVAWRLFGHTPYRIDI
MMAR_3225|M.marinum_M ---MSTWRSPDVGSRLGRFSVWYLLWLVAAAALGYVVWRLFGHIPYRIDI
MUL_3536|M.ulcerans_Agy99 ---MSTLRSPDVGSRLGRVSVWYLLWLVAAAALGYVAWRLFGHIPYRIDI
MLBr_00893|M.leprae_Br4923 ---MSRQQTPEVGNKHRQIGRCCLLWLLAVTALGQVAWQLLGHTPYRIDI
MAV_2312|M.avium_104 ---------------------------------------MFGHTPYRIDI
MSMEG_4247|M.smegmatis_MC2_155 MLEMSKRQSP-RGAGLAPTIAWRVFQLLTLAGVLWVGWRLLGRVPYRIDI
Mvan_3543|M.vanbaalenii_PYR-1 ---MSNRQSP-GGAGWKPTLAWRLFQLLTFAALAAAAWRLLGHVPYRIDI
TH_1105|M.thermoresistible__bu -----------------------MFQLITLAALIWAGWRLLGHLPYRIDI
MAB_0096|M.abscessus_ATCC_1997 -MHSWGGEKRLPRSAVVGALVAAVLAMVVHDHLVPFDVRFFGLTQNGYDL
Mflv_0993|M.gilvum_PYR-GCK ------MSRLALSRPALGVLAGWASLSVVLALTTVGPTANWGLLDGGGDL
* *:
Mb2203|M.bovis_AF2122/97 DIYQMGARAWLDGRPLYGGGVLFHTPIGLNLPFTYPPLAAVLFSPFAWLQ
Rv2181|M.tuberculosis_H37Rv DIYQMGARAWLDGRPLYGGGVLFHTPIGLNLPFTYPPLAAVLFSPFAWLQ
MMAR_3225|M.marinum_M DIYQMGGQAWLDGRPLYSGDVKFHTPIGLDLPFTYPPLSAVVFSPFAWLH
MUL_3536|M.ulcerans_Agy99 DIYQMGGQAWLDGRPLYSGDVKFHTPIGLDLPFTYPPLSAVVFSPFAWLH
MLBr_00893|M.leprae_Br4923 DIYQMGGQAWLDGRPLYSGDVLFHTPIGLNLPFTYPPLAAIAFCPFAWLH
MAV_2312|M.avium_104 DVYQMGARAWMDGRPLYRGDVLFHTPI-VDLPFTYPPLAAIVFCPFAWMH
MSMEG_4247|M.smegmatis_MC2_155 DVYRMGGRAWLDGRPLYADGAIFHTQGGLDLPFTYPPLAAIAFAPFAWLS
Mvan_3543|M.vanbaalenii_PYR-1 DVYRMGGRAWLDGQSLYADGAMFQTRGGLELPFTYPPLAAVAFAPFALLS
TH_1105|M.thermoresistible__bu DVYRMGGRAWLDGDPLYADGAIFETRAGLNLPFTYPPLAAVAFAPFAWLS
MAB_0096|M.abscessus_ATCC_1997 DTYRAAVRGLWDGKRLY------EAPALNQAWFVYPPFATLVLAPLAWAS
Mflv_0993|M.gilvum_PYR-GCK DVYRRGAWHVLSGLPLY------DFPVDKKLFYTYTPFSALVFAPLELLP
* *: . .* ** . . :.*.*:::: :.*:
Mb2203|M.bovis_AF2122/97 MPAASVAITVLTLVLLIASTAIVLTGLDAWPTSRLVPAPARLRRLWLAVL
Rv2181|M.tuberculosis_H37Rv MPAASVAITVLTLVLLIASTAIVLTGLDAWPTSRLVPAPARLRRLWLAVL
MMAR_3225|M.marinum_M MPAASVAITFLTLVVLIASTVVVLTALDVWPDSEQLPGPAWLRRLWLAVI
MUL_3536|M.ulcerans_Agy99 MPAASVAITFLTLVVLTASTVVVLTALDVWPNSEQLPGPAWLRRLWLAVI
MLBr_00893|M.leprae_Br4923 MPAASVAITLTTLMLLIVSTIIVLTRLDVWAMSRAVPGPAWLRRLWLAVI
MAV_2312|M.avium_104 MPTASVAITALTLVLLVVSTVIVLARLDVWSTSALLPGPAWLRRWWLAVV
MSMEG_4247|M.smegmatis_MC2_155 LPLASSAITATTLVLLIVATTIVLTRLDVWPHTTVTSEPAWMRRAWLAAA
Mvan_3543|M.vanbaalenii_PYR-1 LEAASVAITLTTLILLLVSTVIVLTRLDVWPSTRVTSEPAWLRRCWLAAA
TH_1105|M.thermoresistible__bu LEAAAVAITLTTLVLLVVATVIVLTRLDVWPDTAMTTEPAWLRRSWLAAA
MAB_0096|M.abscessus_ATCC_1997 FEVAKWMLLILSLSALALIAWRILRLAGVRADS----------RLGLASA
Mflv_0993|M.gilvum_PYR-GCK AEPDRHIWLALNLAVLIAVVVQSWRLLGYRVDR----------ALVGVSV
.* * . . .
Mb2203|M.bovis_AF2122/97 IVAPATIWLEPISSNFAFGQINVVLMTLVIVDCFPRRTPWPRGLMLGLGI
Rv2181|M.tuberculosis_H37Rv IVAPATIWLEPISSNFAFGQINVVLMTLVIVDCFPRRTPWPRGLMLGLGI
MMAR_3225|M.marinum_M IVAPASLWLEPISSNFAFGQINAVLMTLVILDCFPRRTPWPRGLLLGLGI
MUL_3536|M.ulcerans_Agy99 IVAPASLWLEPISSNFAFGQINAVLMTLVILDCFPRRTPWPRGLLLGLGI
MLBr_00893|M.leprae_Br4923 IVSPAAIWLEPISSNFAFGQINVVLMTLVIADCVPRRTPWPRGLMLGLGI
MAV_2312|M.avium_104 VAAAATIWLEPISSNFAFGQINVVLMTLVIADCLPRRTPWPRGLLLGLGM
MSMEG_4247|M.smegmatis_MC2_155 MVAPAVIYLEPIRSNFEFGQINVVLMTLVIADCVPRRTPWPRGLLLGLAI
Mvan_3543|M.vanbaalenii_PYR-1 IVAPAVLYLEPLRANFDFGQINVVLMTLVIADCVPRRTPWPRGVLLGVAI
TH_1105|M.thermoresistible__bu IVAPAIILLEPIRSNFEFGQINVVLMTLVIADCVPRRTPWPRGALLGVAI
MAB_0096|M.abscessus_ATCC_1997 ALAAIVVDVEPVQATLWWGQINILLMAVVLLDLLGPAQSRWRGVGLGLAA
Mflv_0993|M.gilvum_PYR-GCK LMALGCVFVEPVRTTLFFGQINLILMLLILSDTVGATRSRLAGIGTGLAA
: : :**: :.: :**** :** ::: * . . * *:.
Mb2203|M.bovis_AF2122/97 ALKLTPAVFLLYFLLRRDGRAALTALASFAVATLLGFVLAWRDSWEYWTH
Rv2181|M.tuberculosis_H37Rv ALKLTPAVFLLYFLLRRDGRAALTALASFAVATLLGFVLAWRDSWEYWTH
MMAR_3225|M.marinum_M ALKLTPAVFLLYFLLRRDNRAALTAVASFVVATLAGFALAWRDSWEYWTD
MUL_3536|M.ulcerans_Agy99 ALKLTPAVFLLYFLLRRDNRAALTAVASFVVATLAGFALAWHDSWEYWTD
MLBr_00893|M.leprae_Br4923 ALKLTPAVFLLYFVLRRDNRAALTSWASFAGATLVGFVLAWRDSWEYWTH
MAV_2312|M.avium_104 ALKLTPAVFLLYFLLRRDHRAVLTALASFAGATLLGFVLAYTDSWEYWTH
MSMEG_4247|M.smegmatis_MC2_155 ALKLTPAVFLLYFLLRRDIHTLLRTAATAVVASLAGFALAWSDSVEYWTE
Mvan_3543|M.vanbaalenii_PYR-1 AVKLTPAVFLLYFLLRRDVRALLVTAASAVVATLAGFALAWRDSWEYWLE
TH_1105|M.thermoresistible__bu ALKLTPAVFLLYFLLRRDGRALITASVTAVLATLAGFALAWRDSWEYWTH
MAB_0096|M.abscessus_ATCC_1997 GIKLTPLIFLPYLLCTRQWRAATHALGTMAATVALTWPLLPRDSEWFWS-
Mflv_0993|M.gilvum_PYR-GCK GIKLTPLYFVLYFLTLRQRRVAVTAVAVFAATVVVGLILLPRDSLTYWAG
.:**** *: *:: *: :. : . : * ** :*
Mb2203|M.bovis_AF2122/97 TLHHTDRIGAAALN-TDQNIAGALARLTIGDDERFALWVAGSLLVLAATI
Rv2181|M.tuberculosis_H37Rv TLHHTDRIGAAALN-TDQNIAGALARLTIGDDERFALWVAGSLLVLAATI
MMAR_3225|M.marinum_M TLLHTDRIGSAALN-TDQNIAGALARLPIGEHASHLMWVLLSLGVLAVTV
MUL_3536|M.ulcerans_Agy99 TLLHTDRIGSAALN-TDQNIAGALARLPIGEHASHLLWVLLSLGVLAVTV
MLBr_00893|M.leprae_Br4923 TVHNTERIGAAALN-TDQNIAGALARLGLGEHERFLLWAAGCLLVLAATA
MAV_2312|M.avium_104 TVHHTDRIGSASLN-TDQNIAGALARLGLAQQPRSLLWVAASLLVLAVTV
MSMEG_4247|M.smegmatis_MC2_155 TVRNTDRIGTATLN-TNQNIAGALARLGLGESPRFILWVLACFAVLALTV
Mvan_3543|M.vanbaalenii_PYR-1 TVRNTDRIGTATLN-TNQNIAGVLARLGLGEGERFVVWTVLCFAVLGLTV
TH_1105|M.thermoresistible__bu TVSNTDRIGTATLN-TNQNIAGALARLGLDEDTRFLLWVLACFAVLALTV
MAB_0096|M.abscessus_ATCC_1997 -HLGDTAHISRIDHLANQTINGFLARYFFPQPRPEWLWIALSLLVLAAGL
Mflv_0993|M.gilvum_PYR-GCK TFLRSERIGDRLGHPSNQSLRGMLARLLDDEP-PVWLWLALAVLIGVASL
: ::*.: * *** : :* .. :
Mb2203|M.bovis_AF2122/97 WAMRRVLR-------AGEPTLAVICVALFGLVVSPVSWSHHWVWMLPAVL
Rv2181|M.tuberculosis_H37Rv WAMRRVLR-------AGEPTLAVICVALFGLVVSPVSWSHHWVWMLPAVL
MMAR_3225|M.marinum_M WAMRRVLR-------AEEPSLAVICVALFGLVVSPVSWSHHWVWMLPAVV
MUL_3536|M.ulcerans_Agy99 WAMRRVLR-------AEEPSLAVICVALFGLVVSPVSWSHHWVWMLPAVV
MLBr_00893|M.leprae_Br4923 WAMLRVLR-------AGEPMLAVICVALFGLVVSPVSWSHHWVWMLPAVL
MAV_2312|M.avium_104 WAMRRVLR-------ADEPTLALVCVALFGLVVSPVSWSHHWVWVLPTVL
MSMEG_4247|M.smegmatis_MC2_155 WAARRALRGDTADQTTEAPVLALVCVALFGLVVSPVSWSHHWVWMLPVLV
Mvan_3543|M.vanbaalenii_PYR-1 WAARRALR-------AEQPVLALICVAMFGLVVSPVSWSHHWVWALPTVL
TH_1105|M.thermoresistible__bu WAVRRVLR--SRVCADEASVLALICVAMFGLVVSPVSWSHHWVWALPAVL
MAB_0096|M.abscessus_ATCC_1997 AVAVWAHR-------RGEHALALILVGLTGCAVSPFSWAAHWVWFAPAIV
Mflv_0993|M.gilvum_PYR-GCK TLAVWLHR-------TGERLLSVTVVGLSSAVVSPFSWTHHWVWVVPLMV
* *:: *.: . .***.**: **** * ::
Mb2203|M.bovis_AF2122/97 VIGLLGWRRRN----VALAMLSLAGVVLMRWTPIDLLPQHR---------
Rv2181|M.tuberculosis_H37Rv VIGLLGWRRRN----VALAMLSLAGVVLMRWTPIDLLPQHR---------
MMAR_3225|M.marinum_M VTGVLAWRRRN----VALAVVTIAGLALMRWSPIDLLPKHR---------
MUL_3536|M.ulcerans_Agy99 VTGVLAWRRRN----VALAVVTIAGLALMRWSPIDLLPKHR---------
MLBr_00893|M.leprae_Br4923 VTGILSWRRQN----VAVAVISAAGVALMRWTPIGLLPQHQ---------
MAV_2312|M.avium_104 VTGVLGWRRRN----AALLVLSVVGVALMRWTPIDLLPKHH---------
MSMEG_4247|M.smegmatis_MC2_155 VTAVLAYRRRS----VWFTALTAAGLALTVWTPITLLPEHR---------
Mvan_3543|M.vanbaalenii_PYR-1 VTAVLAVRLRH----VALAVVSAAGLALMVWTPITLLPEHR---------
TH_1105|M.thermoresistible__bu VAAVVSARHRV----RALGVTAAAGVALLVWTPIRLLPENE---------
MAB_0096|M.abscessus_ATCC_1997 WLVAKACTTQGPWSQGWIYRAAGLLALVFMWTLHRPGRGHTTIYFSGVYW
Mflv_0993|M.gilvum_PYR-GCK WFVHRALTCWR-----WWLAPAALFVALGAWPFWFRNLADPRIGF-----
. : : *. .
Mb2203|M.bovis_AF2122/97 ---ETTAVWWRQLAGMSYVWWALAVIVVAGLTVTARMTPQRSLTRGL-TP
Rv2181|M.tuberculosis_H37Rv ---ETTAVWWRQLAGMSYVWWALAVIVVAGLTVTARMTPQRSLTRGL-TP
MMAR_3225|M.marinum_M ---EATAAWWRQLAGMSYVWWALAVIVVAGLTVTTRMTMQRPAEPGR-TP
MUL_3536|M.ulcerans_Agy99 ---EATAAWWRQLAGMSYVWWALAVIVVAGLTVTTRMTMQRPAEPDR-TP
MLBr_00893|M.leprae_Br4923 ---ETTAVWWRQLAGMSYVWWALAVIVATGLTVTTRVTSQDSATQTLLTP
MAV_2312|M.avium_104 ---EASAVWWRQLAGMSYVWWALAVIVAAGVTVTARAASRDAAPQQL-TP
MSMEG_4247|M.smegmatis_MC2_155 ---ETTASLWRQLAGGSYVWWAFAVIVVIGLVSSSRTHTGDAHETDEPLV
Mvan_3543|M.vanbaalenii_PYR-1 ---ETTASLWRQLVGGSYLWWALAVIVVSATVTLPRPGR-DAPGLGAAQP
TH_1105|M.thermoresistible__bu ---EMTASLWRQLLGGSYVWWALVLIVVIGALG---SGSARPRPVDAERV
MAB_0096|M.abscessus_ATCC_1997 NFLDLRPFWAGQLVSGWYPLVFLCFTIATASWLRLSTGGCAEPDELATLT
Mflv_0993|M.gilvum_PYR-GCK -YLFPYTHVPEVLLRNAYLWLFAVLLIWLGVRAARSVAGAKAAGEEPVRA
. * * . : .
Mb2203|M.bovis_AF2122/97 APTAS--------------
Rv2181|M.tuberculosis_H37Rv APTAS--------------
MMAR_3225|M.marinum_M VPAAR--------------
MUL_3536|M.ulcerans_Agy99 APAAR--------------
MLBr_00893|M.leprae_Br4923 VSTAS--------------
MAV_2312|M.avium_104 VTAIG--------------
MSMEG_4247|M.smegmatis_MC2_155 PLARGEAG-----------
Mvan_3543|M.vanbaalenii_PYR-1 ATNGVKA------------
TH_1105|M.thermoresistible__bu PTGG---------------
MAB_0096|M.abscessus_ATCC_1997 ADIEDYPPEIFDEELAVRA
Mflv_0993|M.gilvum_PYR-GCK EE-----------------