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VPNSIDATTIADGGSTRRVARWITWGGPLVLAIALLLHAIVFIHWPTYALQIDVLVYRFGGTRVLDGLDL YSIGRNGEIDDLLFTYTPFAALVFTPLAFITDFTAQVLSLMVFPALLVYSVWRMLNWLNISAKAGLWGLL ALLVGLVSWLEPVRLSIQLGQINLLILAVVVTDILAPKRWRLAGIGIGIVAGIKLTPMIFIVFLFVVGRI RAAVVATVTLIATVGLGFIFLPSASHYYWVDRSFEKISRITRDPTASTSISGLFLRLDLSAGIATALSAL VIVMSLVVATLAYRRNQLLLAISIVGMASAAASPFSWSHHWVWFVPLVVHLGYRGYVLGKRASAITMWAF CVVFAAWFTSLSGKTPDSGALTLRPGGVLNEVIPSLYVFVHLVVLVASWIWLRRDTPGVNDVAGEDESPP ADELAPASPAHN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1985 | - | - | 100% (432) | hypothetical protein MAB_1985 |
| M. abscessus ATCC 19977 | MAB_0281 | - | 2e-46 | 34.72% (360) | hypothetical protein MAB_0281 |
| M. abscessus ATCC 19977 | MAB_0096 | - | 3e-44 | 31.67% (420) | hypothetical protein MAB_0096 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1190 | pimE | 2e-30 | 32.42% (293) | mannosyltransferase |
| M. gilvum PYR-GCK | Mflv_0993 | - | 7e-48 | 34.54% (388) | hypothetical protein Mflv_0993 |
| M. tuberculosis H37Rv | Rv1159 | pimE | 2e-30 | 32.42% (293) | mannosyltransferase |
| M. leprae Br4923 | MLBr_01504 | pimE | 1e-30 | 29.29% (379) | mannosyltransferase |
| M. marinum M | MMAR_4292 | pimE | 1e-30 | 30.21% (384) | transmembrane protein |
| M. avium 104 | MAV_2312 | - | 6e-31 | 27.32% (377) | hypothetical protein MAV_2312 |
| M. smegmatis MC2 155 | MSMEG_4247 | - | 2e-29 | 26.78% (351) | integral membrane protein |
| M. thermoresistible (build 8) | TH_1105 | - | 9e-30 | 29.03% (341) | Probable conserved integral membrane protein |
| M. ulcerans Agy99 | MUL_3536 | - | 8e-31 | 30.32% (343) | hypothetical protein MUL_3536 |
| M. vanbaalenii PYR-1 | Mvan_3543 | - | 2e-33 | 31.21% (298) | putative integral membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4247|M.smegmatis_MC2_155 ------------------------MLEMSKRQSPRGAGLAPTIAWRVFQL
Mvan_3543|M.vanbaalenii_PYR-1 ---------------------------MSNRQSPGGAGWKPTLAWRLFQL
TH_1105|M.thermoresistible__bu ----------------------------------------------MFQL
MAV_2312|M.avium_104 --------------------------------------------------
MUL_3536|M.ulcerans_Agy99 --------------------------MSTLRSPDVGSRLGRVSVWYLLWL
Mb1190|M.bovis_AF2122/97 MCRTLIDGPVRSAIAKVRQIDTTSSTPAAAR---RVTSPPARETRAAVLL
Rv1159|M.tuberculosis_H37Rv MCRTLIDGPVRSAIAKVRQIDTTSSTPAAAR---RVTSPPARETRAAVLL
MMAR_4292|M.marinum_M MTGHLGN----WVGTRVGRIDTTSAAPAASTTRHKAVSPKVWGRRGAPLL
MLBr_01504|M.leprae_Br4923 MVAVIMAK-AFAAVARVGQIDTTTTNTTAAASAPRVRRLTSRLNAAAPLL
Mflv_0993|M.gilvum_PYR-GCK --------------------------MSRLALSRPALGVLAGWASLSVVL
MAB_1985|M.abscessus_ATCC_1997 --------------------MPNSIDATTIADGGSTRRVARWITWGGPLV
MSMEG_4247|M.smegmatis_MC2_155 LTLAGVLWVGWRLLG-RVPYRIDIDVYRMGGRAWLDGRPLYADGAIFHTQ
Mvan_3543|M.vanbaalenii_PYR-1 LTFAALAAAAWRLLG-HVPYRIDIDVYRMGGRAWLDGQSLYADGAMFQTR
TH_1105|M.thermoresistible__bu ITLAALIWAGWRLLG-HLPYRIDIDVYRMGGRAWLDGDPLYADGAIFETR
MAV_2312|M.avium_104 ------------MFG-HTPYRIDIDVYQMGARAWMDGRPLYRGDVLFHTP
MUL_3536|M.ulcerans_Agy99 VAAAALGYVAWRLFG-HIPYRIDIDIYQMGGQAWLDGRPLYSGDVKFHTP
Mb1190|M.bovis_AF2122/97 LVLSVGARLAWTYLAPNGANFVDLHVYVSGAASLDHPGTLYG-YVYADQT
Rv1159|M.tuberculosis_H37Rv LVLSVGARLAWTYLAPNGANFVDLHVYVSGAASLDHPGTLYG-YVYADQT
MMAR_4292|M.marinum_M LVFSVAARLAWTYLTSNGANFVDLHVYVGGAAALDHPGSLYS-YVYADQT
MLBr_01504|M.leprae_Br4923 LVFSVAVRLAWTYLAPNGANFVDLHVYLGGAATIDHPGTLYR-YVYVDQT
Mflv_0993|M.gilvum_PYR-GCK ALTTVGPTANWGLLD----GGGDLDVYRRGAWHVLSGLPLYD------FP
MAB_1985|M.abscessus_ATCC_1997 LAIALLLHAIVFIHWPTYALQIDVLVYRFGGTRVLDGLDLYS---IGRNG
*: :* *. **
MSMEG_4247|M.smegmatis_MC2_155 GGLDLPFTYPPLAAIAFAPFAWLSLPLASSAITATTLVLLIVATTIVLTR
Mvan_3543|M.vanbaalenii_PYR-1 GGLELPFTYPPLAAVAFAPFALLSLEAASVAITLTTLILLLVSTVIVLTR
TH_1105|M.thermoresistible__bu AGLNLPFTYPPLAAVAFAPFAWLSLEAAAVAITLTTLVLLVVATVIVLTR
MAV_2312|M.avium_104 I-VDLPFTYPPLAAIVFCPFAWMHMPTASVAITALTLVLLVVSTVIVLAR
MUL_3536|M.ulcerans_Agy99 IGLDLPFTYPPLSAVVFSPFAWLHMPAASVAITFLTLVVLTASTVVVLTA
Mb1190|M.bovis_AF2122/97 PDFPLPFTYPPFAAVVFYPLHLVPFGLIALLWQVVTMAALYGAVRISQRL
Rv1159|M.tuberculosis_H37Rv PDFPLPFTYPPFAAVVFYPLHLVPFGLIALLWQVVTMAALYGAVRISQRL
MMAR_4292|M.marinum_M PDFPLPFTYPPFAAVVFYPLHLLPFGLVAFLWQLATIAALYGAVRISQRL
MLBr_01504|M.leprae_Br4923 PDFPLPFTYPPFAAVVFYPLHLLPFALVAFLWQITTIAALYGAVRISQRL
Mflv_0993|M.gilvum_PYR-GCK VDKKLFYTYTPFSALVFAPLELLPAEPDRHIWLALNLAVLIAVVVQSWRL
MAB_1985|M.abscessus_ATCC_1997 EIDDLLFTYTPFAALVFTPLAFITDFTAQVLSLMVFPALLVYSVWRMLNW
* :**.*::*:.* *: : * .
MSMEG_4247|M.smegmatis_MC2_155 LDVWPHTTVTSEPAWMRRAWLAAAMVAPAVIYLEPIRSNFEFGQINVVLM
Mvan_3543|M.vanbaalenii_PYR-1 LDVWPSTRVTSEPAWLRRCWLAAAIVAPAVLYLEPLRANFDFGQINVVLM
TH_1105|M.thermoresistible__bu LDVWPDTAMTTEPAWLRRSWLAAAIVAPAIILLEPIRSNFEFGQINVVLM
MAV_2312|M.avium_104 LDVWSTSALLPGPAWLRRWWLAVVVAAAATIWLEPISSNFAFGQINVVLM
MUL_3536|M.ulcerans_Agy99 LDVWPNSEQLPGPAWLRRLWLAVIIVAPASLWLEPISSNFAFGQINAVLM
Mb1190|M.bovis_AF2122/97 MGGTAETG-----------HFAAMLWTAIAIWIEPLRSTFDYGQINVLLM
Rv1159|M.tuberculosis_H37Rv MGGTAETG-----------HFAAMLWTAIAIWIEPLRSTFDYGQINVLLM
MMAR_4292|M.marinum_M IGVPAERG-----------HRAAMVWTAVAIWIEPLRSTFDYGQINVLLM
MLBr_01504|M.leprae_Br4923 LGVSSHTG-----------HRVALLWTAIAIWIEPLRSAFDYGQINVLPM
Mflv_0993|M.gilvum_PYR-GCK LGYRVDRALVG----------VSVLMALGCVFVEPVRTTLFFGQINLILM
MAB_1985|M.abscessus_ATCC_1997 LNISAKAG----------LWGLLALLVGLVSWLEPVRLSIQLGQINLLIL
:. : . :**: : **** : :
MSMEG_4247|M.smegmatis_MC2_155 TLVIADCVPRRTPWPRGLLLGLAIALKLTPAVFLLYFLLRRDIHTLLRTA
Mvan_3543|M.vanbaalenii_PYR-1 TLVIADCVPRRTPWPRGVLLGVAIAVKLTPAVFLLYFLLRRDVRALLVTA
TH_1105|M.thermoresistible__bu TLVIADCVPRRTPWPRGALLGVAIALKLTPAVFLLYFLLRRDGRALITAS
MAV_2312|M.avium_104 TLVIADCLPRRTPWPRGLLLGLGMALKLTPAVFLLYFLLRRDHRAVLTAL
MUL_3536|M.ulcerans_Agy99 TLVILDCFPRRTPWPRGLLLGLGIALKLTPAVFLLYFLLRRDNRAALTAV
Mb1190|M.bovis_AF2122/97 LAALWAVYTPR-WWLSGLLVGVASGVKLTPAITAVYLVGVRRLHAAAFSV
Rv1159|M.tuberculosis_H37Rv LAALWAVYTPR-WWLSGLLVGVASGVKLTPAITAVYLVGVRRLHAAAFSV
MMAR_4292|M.marinum_M LAALWAVYTTR-WWLSGLLVGVAAGIKLTPAITAVYLAGVRRWRAAVCSA
MLBr_01504|M.leprae_Br4923 LGVLWAVYTTR-NWLSGLLVGVAGGIKLTPAIAAVYFLGARRVRAAALSA
Mflv_0993|M.gilvum_PYR-GCK LLILSDTVGATRSRLAGIGTGLAAGIKLTPLYFVLYFLTLRQRRVAVTAV
MAB_1985|M.abscessus_ATCC_1997 AVVVTDILAPKRWRLAGIGIGIVAGIKLTPMIFIVFLFVVGRIRAAVVAT
: * *: .:**** ::: :. :
MSMEG_4247|M.smegmatis_MC2_155 ATAVVASLAGFALAWSDSVEYWTE-TVRNTDRIGT-ATLNTNQNIAGALA
Mvan_3543|M.vanbaalenii_PYR-1 ASAVVATLAGFALAWRDSWEYWLE-TVRNTDRIGT-ATLNTNQNIAGVLA
TH_1105|M.thermoresistible__bu VTAVLATLAGFALAWRDSWEYWTH-TVSNTDRIGT-ATLNTNQNIAGALA
MAV_2312|M.avium_104 ASFAGATLLGFVLAYTDSWEYWTH-TVHHTDRIGS-ASLNTDQNIAGALA
MUL_3536|M.ulcerans_Agy99 ASFVVATLAGFALAWHDSWEYWTD-TLLHTDRIGS-AALNTDQNIAGALA
Mb1190|M.bovis_AF2122/97 VVFLATVGVSLLVVGDEARYYFTD-LLGDAGRVGP-IATSFNQSWRGAIS
Rv1159|M.tuberculosis_H37Rv VVFLATVGVSLLVVGDEARYYFTD-LLGDAGRVGP-IATSFNQSWRGAIS
MMAR_4292|M.marinum_M IVFLVSVGVSLLIVGGQARYYFTD-LLGDAHRVGP-IATSFNQSWRGAIS
MLBr_01504|M.leprae_Br4923 AVFGATVAVSALVVGDQARYYFTE-LLGDAHRVGP-IATSFNQSWRGGIS
Mflv_0993|M.gilvum_PYR-GCK AVFAATVVVGLILLPRDSLTYWAG-TFLRSERIGDRLGHPSNQSLRGMLA
MAB_1985|M.abscessus_ATCC_1997 VTLIATVGLGFIFLPSASHYYWVDRSFEKISRITR--DPTASTSISGLFL
: . . : *: . *: . . * :
MSMEG_4247|M.smegmatis_MC2_155 RLGLGESPRFILWVLACFAVLALTVWAARRALRGDTADQTTEAPVLALVC
Mvan_3543|M.vanbaalenii_PYR-1 RLGLGEGERFVVWTVLCFAVLGLTVWAARRALR-------AEQPVLALIC
TH_1105|M.thermoresistible__bu RLGLDEDTRFLLWVLACFAVLALTVWAVRRVLR--SRVCADEASVLALIC
MAV_2312|M.avium_104 RLGLAQQPRSLLWVAASLLVLAVTVWAMRRVLR-------ADEPTLALVC
MUL_3536|M.ulcerans_Agy99 RLPIGEHASHLLWVLLSLGVLAVTVWAMRRVLR-------AEEPSLAVIC
Mb1190|M.bovis_AF2122/97 RI-LGHDAGFGPLVLAAIASTAVLAILAWRALD-------RSDRLGKLLV
Rv1159|M.tuberculosis_H37Rv RI-LGHDAGFGPLVLAAIASTAVLAILAWRALD-------RSDRLGKLLV
MMAR_4292|M.marinum_M RI-LGHDAGFGPLVLAAIAVTAVLAVLAWRALE-------PADHLGKLLV
MLBr_01504|M.leprae_Br4923 RI-MGYDAGLGPLVLAAIAITAVVAVVAWRALD-------RPDRLGKLLV
Mflv_0993|M.gilvum_PYR-GCK RLLDDEPPVWLWLALAVLIGVASLTLAVWLHRT--------GERLLSVTV
MAB_1985|M.abscessus_ATCC_1997 RLDLSAG---IATALSALVIVMSLVVATLAYRR--------NQLLLAISI
*: . : . :
MSMEG_4247|M.smegmatis_MC2_155 VALFGLVVSPVSWSHHWVWMLPVLVVTAVLAYRRRSVWFTALTAAGLA--
Mvan_3543|M.vanbaalenii_PYR-1 VAMFGLVVSPVSWSHHWVWALPTVLVTAVLAVRLRHVALAVVSAAGLA--
TH_1105|M.thermoresistible__bu VAMFGLVVSPVSWSHHWVWALPAVLVAAVVSARHRVRALGVTAAAGVA--
MAV_2312|M.avium_104 VALFGLVVSPVSWSHHWVWVLPTVLVTGVLGWRRRNAALLVLSVVGVA--
MUL_3536|M.ulcerans_Agy99 VALFGLVVSPVSWSHHWVWMLPAVVVTGVLAWRRRNVALAVVTIAGLA--
Mb1190|M.bovis_AF2122/97 VELFGLLLSPISWTHHWVWLVPLMIWLIDGPARER----PGARILGWG--
Rv1159|M.tuberculosis_H37Rv VELFGLLLSPISWTHHWVWLVPLMIWLIDGPARER----PGARILGWG--
MMAR_4292|M.marinum_M VELFGLLLSPISWTHHWVWLVPLMIWLLSGPLRDR----LGARILGWG--
MLBr_01504|M.leprae_Br4923 VELFGLLLSPISWTHHWVWLVPLMIWLIHGPLGER----PGAQIVGWG--
Mflv_0993|M.gilvum_PYR-GCK VGLSSAVVSPFSWTHHWVWVVPLMVWFVHRALTCWRWWLAPAALFVALGA
MAB_1985|M.abscessus_ATCC_1997 VGMASAAASPFSWSHHWVWFVPLVVHLGYRGYVLG-KRASAITMWAFCVV
* : . **.**:***** :* ::
MSMEG_4247|M.smegmatis_MC2_155 ---LTVWTPITLLP--EHRETTASLWRQLAGGSYVWWAFAVIVVIGLVSS
Mvan_3543|M.vanbaalenii_PYR-1 ---LMVWTPITLLP--EHRETTASLWRQLVGGSYLWWALAVIVVSATVTL
TH_1105|M.thermoresistible__bu ---LLVWTPIRLLP--ENEEMTASLWRQLLGGSYVWWALVLIVVIGALGS
MAV_2312|M.avium_104 ---LMRWTPIDLLP--KHHEASAVWWRQLAGMSYVWWALAVIVAAGVTVT
MUL_3536|M.ulcerans_Agy99 ---LMRWSPIDLLP--KHREATAAWWRQLAGMSYVWWALAVIVVAGLTVT
Mb1190|M.bovis_AF2122/97 ---WLVLTIVGVPW--LLSFAQPSIW-QIGRPWYLAWAGLVYVVATLATL
Rv1159|M.tuberculosis_H37Rv ---WLVLTIVGVPW--LLSFAQPSIW-QIGRPWYLAWAGLVYVVATLATL
MMAR_4292|M.marinum_M ---WLALTVIGVPW--LLSFAQPTIW-QIGRPWYLAWAGLVYVVATLATL
MLBr_01504|M.leprae_Br4923 ---WLALSVVGVPW--LLSFAQPTIW-QLGRPWYLAWGGLVYIVVALVTL
Mflv_0993|M.gilvum_PYR-GCK WPFWFRNLADPRIG--FYLFPYTHVPEVLLRNAYLWLFAVLLIWLGVRAA
MAB_1985|M.abscessus_ATCC_1997 FAAWFTSLSGKTPDSGALTLRPGGVLNEVIPSLYVFVHLVVLVASWIWLR
: *: : :
MSMEG_4247|M.smegmatis_MC2_155 SRTHTGDAHETDEPLVPLARGEAG-----
Mvan_3543|M.vanbaalenii_PYR-1 PRPGR-DAPGLGAAQPATNGVKA------
TH_1105|M.thermoresistible__bu GSARP---RPVDAERVPTGG---------
MAV_2312|M.avium_104 ARAASRDAAPQQLTPVTAIG---------
MUL_3536|M.ulcerans_Agy99 TRMTMQRPAEPDRTPAPAAR---------
Mb1190|M.bovis_AF2122/97 GWIAASERYVRIRPRRMAN----------
Rv1159|M.tuberculosis_H37Rv GWIAASERYVRIRPRRMAN----------
MMAR_4292|M.marinum_M GWIATTRQRAR------------------
MLBr_01504|M.leprae_Br4923 IWIVVIGKHPVVASPR-------------
Mflv_0993|M.gilvum_PYR-GCK RSVAGAKAAGEEPVRAEE-----------
MAB_1985|M.abscessus_ATCC_1997 RDTPGVNDVAGEDESPPADELAPASPAHN