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MSTLRSPDVGSRLGRVSVWYLLWLVAAAALGYVAWRLFGHIPYRIDIDIYQMGGQAWLDGRPLYSGDVKF HTPIGLDLPFTYPPLSAVVFSPFAWLHMPAASVAITFLTLVVLTASTVVVLTALDVWPNSEQLPGPAWLR RLWLAVIIVAPASLWLEPISSNFAFGQINAVLMTLVILDCFPRRTPWPRGLLLGLGIALKLTPAVFLLYF LLRRDNRAALTAVASFVVATLAGFALAWHDSWEYWTDTLLHTDRIGSAALNTDQNIAGALARLPIGEHAS HLLWVLLSLGVLAVTVWAMRRVLRAEEPSLAVICVALFGLVVSPVSWSHHWVWMLPAVVVTGVLAWRRRN VALAVVTIAGLALMRWSPIDLLPKHREATAAWWRQLAGMSYVWWALAVIVVAGLTVTTRMTMQRPAEPDR TPAPAAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3536 | - | - | 100% (427) | hypothetical protein MUL_3536 |
| M. ulcerans Agy99 | MUL_1006 | pimE | 5e-36 | 32.22% (419) | mannosyltransferase |
| M. ulcerans Agy99 | MUL_0069 | - | 9e-06 | 26.20% (313) | hypothetical protein MUL_0069 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2203 | - | 0.0 | 79.81% (426) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_2968 | - | 1e-153 | 66.42% (411) | putative integral membrane protein |
| M. tuberculosis H37Rv | Rv2181 | - | 0.0 | 79.81% (426) | integral membrane protein |
| M. leprae Br4923 | MLBr_00893 | - | 0.0 | 76.20% (416) | hypothetical protein MLBr_00893 |
| M. abscessus ATCC 19977 | MAB_1304 | pimE | 1e-36 | 33.25% (397) | mannosyltransferase |
| M. marinum M | MMAR_3225 | - | 0.0 | 97.89% (427) | hypothetical protein MMAR_3225 |
| M. avium 104 | MAV_2312 | - | 1e-177 | 75.84% (389) | hypothetical protein MAV_2312 |
| M. smegmatis MC2 155 | MSMEG_4247 | - | 1e-156 | 63.36% (434) | integral membrane protein |
| M. thermoresistible (build 8) | TH_1105 | - | 1e-150 | 65.10% (404) | Probable conserved integral membrane protein |
| M. vanbaalenii PYR-1 | Mvan_3543 | - | 1e-156 | 64.54% (423) | putative integral membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2968|M.gilvum_PYR-GCK -----------MSNRRSP-GGAGWGPRLLWRLFQLLTLAALVIAASRLLG
Mvan_3543|M.vanbaalenii_PYR-1 -----------MSNRQSP-GGAGWKPTLAWRLFQLLTFAALAAAAWRLLG
MSMEG_4247|M.smegmatis_MC2_155 --------MLEMSKRQSP-RGAGLAPTIAWRVFQLLTLAGVLWVGWRLLG
TH_1105|M.thermoresistible__bu -------------------------------MFQLITLAALIWAGWRLLG
MUL_3536|M.ulcerans_Agy99 -----------MSTLRSPDVGSRLGRVSVWYLLWLVAAAALGYVAWRLFG
MMAR_3225|M.marinum_M -----------MSTWRSPDVGSRLGRFSVWYLLWLVAAAALGYVVWRLFG
Mb2203|M.bovis_AF2122/97 -----------MSAWRAPEVGSRLGRRVLWCLLWLLAGVALGYVAWRLFG
Rv2181|M.tuberculosis_H37Rv -----------MSAWRAPEVGSRLGRRVLWCLLWLLAGVALGYVAWRLFG
MLBr_00893|M.leprae_Br4923 -----------MSRQQTPEVGNKHRQIGRCCLLWLLAVTALGQVAWQLLG
MAV_2312|M.avium_104 -----------------------------------------------MFG
MAB_1304|M.abscessus_ATCC_1997 MATEKTEPTRANVEPPMPTRGASAWRRVRAWGPWLLGLSVAVRLAWAYLT
:
Mflv_2968|M.gilvum_PYR-GCK -HVPYRIDIDVYRMGGRAWLDGRSLYADGAMFQTRGGLELPFTYPPLAAV
Mvan_3543|M.vanbaalenii_PYR-1 -HVPYRIDIDVYRMGGRAWLDGQSLYADGAMFQTRGGLELPFTYPPLAAV
MSMEG_4247|M.smegmatis_MC2_155 -RVPYRIDIDVYRMGGRAWLDGRPLYADGAIFHTQGGLDLPFTYPPLAAI
TH_1105|M.thermoresistible__bu -HLPYRIDIDVYRMGGRAWLDGDPLYADGAIFETRAGLNLPFTYPPLAAV
MUL_3536|M.ulcerans_Agy99 -HIPYRIDIDIYQMGGQAWLDGRPLYSGDVKFHTPIGLDLPFTYPPLSAV
MMAR_3225|M.marinum_M -HIPYRIDIDIYQMGGQAWLDGRPLYSGDVKFHTPIGLDLPFTYPPLSAV
Mb2203|M.bovis_AF2122/97 -HTPYRIDIDIYQMGARAWLDGRPLYGGGVLFHTPIGLNLPFTYPPLAAV
Rv2181|M.tuberculosis_H37Rv -HTPYRIDIDIYQMGARAWLDGRPLYGGGVLFHTPIGLNLPFTYPPLAAV
MLBr_00893|M.leprae_Br4923 -HTPYRIDIDIYQMGGQAWLDGRPLYSGDVLFHTPIGLNLPFTYPPLAAI
MAV_2312|M.avium_104 -HTPYRIDIDVYQMGARAWMDGRPLYRGDVLFHTPI-VDLPFTYPPLAAI
MAB_1304|M.abscessus_ATCC_1997 PHGADLVDLHVYVSGPATLGHGN--LYEFTYPDKTPDFPLPFTYPPFAAV
: . :*:.:* * : .* . .. . *******::*:
Mflv_2968|M.gilvum_PYR-GCK AFSPFAMLSLEAASLAITATTLVLLLVSTVIVLTRLDVWPTTGVTREPAW
Mvan_3543|M.vanbaalenii_PYR-1 AFAPFALLSLEAASVAITLTTLILLLVSTVIVLTRLDVWPSTRVTSEPAW
MSMEG_4247|M.smegmatis_MC2_155 AFAPFAWLSLPLASSAITATTLVLLIVATTIVLTRLDVWPHTTVTSEPAW
TH_1105|M.thermoresistible__bu AFAPFAWLSLEAAAVAITLTTLVLLVVATVIVLTRLDVWPDTAMTTEPAW
MUL_3536|M.ulcerans_Agy99 VFSPFAWLHMPAASVAITFLTLVVLTASTVVVLTALDVWPNSEQLPGPAW
MMAR_3225|M.marinum_M VFSPFAWLHMPAASVAITFLTLVVLIASTVVVLTALDVWPDSEQLPGPAW
Mb2203|M.bovis_AF2122/97 LFSPFAWLQMPAASVAITVLTLVLLIASTAIVLTGLDAWPTSRLVPAPAR
Rv2181|M.tuberculosis_H37Rv LFSPFAWLQMPAASVAITVLTLVLLIASTAIVLTGLDAWPTSRLVPAPAR
MLBr_00893|M.leprae_Br4923 AFCPFAWLHMPAASVAITLTTLMLLIVSTIIVLTRLDVWAMSRAVPGPAW
MAV_2312|M.avium_104 VFCPFAWMHMPTASVAITALTLVLLVVSTVIVLARLDVWSTSALLPGPAW
MAB_1304|M.abscessus_ATCC_1997 VFWPLHLIPFTLLGLCWILGTIAALYAVVRLSQRLLGFDDAR--------
* *: : : . . *: * . . : *.
Mflv_2968|M.gilvum_PYR-GCK VRRCWLAAAIVAPAVIFCEPIRANFDFGQINVVLMTLVLADCVPRRTPCP
Mvan_3543|M.vanbaalenii_PYR-1 LRRCWLAAAIVAPAVLYLEPLRANFDFGQINVVLMTLVIADCVPRRTPWP
MSMEG_4247|M.smegmatis_MC2_155 MRRAWLAAAMVAPAVIYLEPIRSNFEFGQINVVLMTLVIADCVPRRTPWP
TH_1105|M.thermoresistible__bu LRRSWLAAAIVAPAIILLEPIRSNFEFGQINVVLMTLVIADCVPRRTPWP
MUL_3536|M.ulcerans_Agy99 LRRLWLAVIIVAPASLWLEPISSNFAFGQINAVLMTLVILDCFPRRTPWP
MMAR_3225|M.marinum_M LRRLWLAVIIVAPASLWLEPISSNFAFGQINAVLMTLVILDCFPRRTPWP
Mb2203|M.bovis_AF2122/97 LRRLWLAVLIVAPATIWLEPISSNFAFGQINVVLMTLVIVDCFPRRTPWP
Rv2181|M.tuberculosis_H37Rv LRRLWLAVLIVAPATIWLEPISSNFAFGQINVVLMTLVIVDCFPRRTPWP
MLBr_00893|M.leprae_Br4923 LRRLWLAVIIVSPAAIWLEPISSNFAFGQINVVLMTLVIADCVPRRTPWP
MAV_2312|M.avium_104 LRRWWLAVVVAAAATIWLEPISSNFAFGQINVVLMTLVIADCLPRRTPWP
MAB_1304|M.abscessus_ATCC_1997 ------AAAVWTAVTMWTEPVRSTLDYGQINVLLMLLILLAVASSR-WWI
*. : :.. : **: :.: :****.:** *:: . *
Mflv_2968|M.gilvum_PYR-GCK RGVLLGLAIAVKLTPAVFLLYFLLRRDTRALLVTAASVVVATLAGFAFAW
Mvan_3543|M.vanbaalenii_PYR-1 RGVLLGVAIAVKLTPAVFLLYFLLRRDVRALLVTAASAVVATLAGFALAW
MSMEG_4247|M.smegmatis_MC2_155 RGLLLGLAIALKLTPAVFLLYFLLRRDIHTLLRTAATAVVASLAGFALAW
TH_1105|M.thermoresistible__bu RGALLGVAIALKLTPAVFLLYFLLRRDGRALITASVTAVLATLAGFALAW
MUL_3536|M.ulcerans_Agy99 RGLLLGLGIALKLTPAVFLLYFLLRRDNRAALTAVASFVVATLAGFALAW
MMAR_3225|M.marinum_M RGLLLGLGIALKLTPAVFLLYFLLRRDNRAALTAVASFVVATLAGFALAW
Mb2203|M.bovis_AF2122/97 RGLMLGLGIALKLTPAVFLLYFLLRRDGRAALTALASFAVATLLGFVLAW
Rv2181|M.tuberculosis_H37Rv RGLMLGLGIALKLTPAVFLLYFLLRRDGRAALTALASFAVATLLGFVLAW
MLBr_00893|M.leprae_Br4923 RGLMLGLGIALKLTPAVFLLYFVLRRDNRAALTSWASFAGATLVGFVLAW
MAV_2312|M.avium_104 RGLLLGLGMALKLTPAVFLLYFLLRRDHRAVLTALASFAGATLLGFVLAY
MAB_1304|M.abscessus_ATCC_1997 SGTLIGLAGGVKLTPLVSGLYFLGARRWTTAIWAGVVFLLTVVVGIAVVG
* ::*:. .:**** * ***: * : : : . : : *:...
Mflv_2968|M.gilvum_PYR-GCK SDSWEYWTETVRNTDRIGTATLNTNQNIAGALARLGLGEDARFLLWVALC
Mvan_3543|M.vanbaalenii_PYR-1 RDSWEYWLETVRNTDRIGTATLNTNQNIAGVLARLGLGEGERFVVWTVLC
MSMEG_4247|M.smegmatis_MC2_155 SDSVEYWTETVRNTDRIGTATLNTNQNIAGALARLGLGESPRFILWVLAC
TH_1105|M.thermoresistible__bu RDSWEYWTHTVSNTDRIGTATLNTNQNIAGALARLGLDEDTRFLLWVLAC
MUL_3536|M.ulcerans_Agy99 HDSWEYWTDTLLHTDRIGSAALNTDQNIAGALARLPIGEHASHLLWVLLS
MMAR_3225|M.marinum_M RDSWEYWTDTLLHTDRIGSAALNTDQNIAGALARLPIGEHASHLMWVLLS
Mb2203|M.bovis_AF2122/97 RDSWEYWTHTLHHTDRIGAAALNTDQNIAGALARLTIGDDERFALWVAGS
Rv2181|M.tuberculosis_H37Rv RDSWEYWTHTLHHTDRIGAAALNTDQNIAGALARLTIGDDERFALWVAGS
MLBr_00893|M.leprae_Br4923 RDSWEYWTHTVHNTERIGAAALNTDQNIAGALARLGLGEHERFLLWAAGC
MAV_2312|M.avium_104 TDSWEYWTHTVHHTDRIGSASLNTDQNIAGALARLGLAQQPRSLLWVAAS
MAB_1304|M.abscessus_ATCC_1997 EQGRYYFTDLLGKPDRIGPIATVFNQSWRGGISRI-LGHDAGSGVLVLFA
:. *: . : :.:***. : :*. * ::*: : . : . .
Mflv_2968|M.gilvum_PYR-GCK FAVLALTVWAARRALR-------ADQPVLALISVAMFGLVVSPVSWSHHW
Mvan_3543|M.vanbaalenii_PYR-1 FAVLGLTVWAARRALR-------AEQPVLALICVAMFGLVVSPVSWSHHW
MSMEG_4247|M.smegmatis_MC2_155 FAVLALTVWAARRALRGDTADQTTEAPVLALVCVALFGLVVSPVSWSHHW
TH_1105|M.thermoresistible__bu FAVLALTVWAVRRVLR--SRVCADEASVLALICVAMFGLVVSPVSWSHHW
MUL_3536|M.ulcerans_Agy99 LGVLAVTVWAMRRVLR-------AEEPSLAVICVALFGLVVSPVSWSHHW
MMAR_3225|M.marinum_M LGVLAVTVWAMRRVLR-------AEEPSLAVICVALFGLVVSPVSWSHHW
Mb2203|M.bovis_AF2122/97 LLVLAATIWAMRRVLR-------AGEPTLAVICVALFGLVVSPVSWSHHW
Rv2181|M.tuberculosis_H37Rv LLVLAATIWAMRRVLR-------AGEPTLAVICVALFGLVVSPVSWSHHW
MLBr_00893|M.leprae_Br4923 LLVLAATAWAMLRVLR-------AGEPMLAVICVALFGLVVSPVSWSHHW
MAV_2312|M.avium_104 LLVLAVTVWAMRRVLR-------ADEPTLALVCVALFGLVVSPVSWSHHW
MAB_1304|M.abscessus_ATCC_1997 YAVTAILAFLAWRAVN---------DRLGQICVVEMFGLLISPISWTHHW
* . : *.:. : * :***::**:**:***
Mflv_2968|M.gilvum_PYR-GCK VWMLPTVVVTAVLAVRLRHALLGAVATLGLVLMVWSPITLLPEHRETTAA
Mvan_3543|M.vanbaalenii_PYR-1 VWALPTVLVTAVLAVRLRHVALAVVSAAGLALMVWTPITLLPEHRETTAS
MSMEG_4247|M.smegmatis_MC2_155 VWMLPVLVVTAVLAYRRRSVWFTALTAAGLALTVWTPITLLPEHRETTAS
TH_1105|M.thermoresistible__bu VWALPAVLVAAVVSARHRVRALGVTAAAGVALLVWTPIRLLPENEEMTAS
MUL_3536|M.ulcerans_Agy99 VWMLPAVVVTGVLAWRRRNVALAVVTIAGLALMRWSPIDLLPKHREATAA
MMAR_3225|M.marinum_M VWMLPAVVVTGVLAWRRRNVALAVVTIAGLALMRWSPIDLLPKHREATAA
Mb2203|M.bovis_AF2122/97 VWMLPAVLVIGLLGWRRRNVALAMLSLAGVVLMRWTPIDLLPQHRETTAV
Rv2181|M.tuberculosis_H37Rv VWMLPAVLVIGLLGWRRRNVALAMLSLAGVVLMRWTPIDLLPQHRETTAV
MLBr_00893|M.leprae_Br4923 VWMLPAVLVTGILSWRRQNVAVAVISAAGVALMRWTPIGLLPQHQETTAV
MAV_2312|M.avium_104 VWVLPTVLVTGVLGWRRRNAALLVLSVVGVALMRWTPIDLLPKHHEASAV
MAB_1304|M.abscessus_ATCC_1997 VWMVPFMVWLLHGPWRDKVGAKVFGCGWLVLLLIGVPWLLS----FAQPD
** :* :: * : : * * * .
Mflv_2968|M.gilvum_PYR-GCK LWRQLVGGSYLWWALAVIVAIGTVTLHRDTTPGVDAREPG-AEPGTEVLK
Mvan_3543|M.vanbaalenii_PYR-1 LWRQLVGGSYLWWALAVIVVSATVTLPR---PGRDAPGLGAAQPATNGVK
MSMEG_4247|M.smegmatis_MC2_155 LWRQLAGGSYVWWAFAVIVVIGLVSSSR--THTGDAHETDEPLVPLARGE
TH_1105|M.thermoresistible__bu LWRQLLGGSYVWWALVLIVVIGALGSGS-----ARPRPVDAERVPTGG--
MUL_3536|M.ulcerans_Agy99 WWRQLAGMSYVWWALAVIVVAGLTVTTRMTMQRPAEPDR-TPAPAAR---
MMAR_3225|M.marinum_M WWRQLAGMSYVWWALAVIVVAGLTVTTRMTMQRPAEPGR-TPVPAAR---
Mb2203|M.bovis_AF2122/97 WWRQLAGMSYVWWALAVIVVAGLTVTARMTPQRSLTRGL-TPAPTAS---
Rv2181|M.tuberculosis_H37Rv WWRQLAGMSYVWWALAVIVVAGLTVTARMTPQRSLTRGL-TPAPTAS---
MLBr_00893|M.leprae_Br4923 WWRQLAGMSYVWWALAVIVATGLTVTTRVTSQDSATQTLLTPVSTAS---
MAV_2312|M.avium_104 WWRQLAGMSYVWWALAVIVAAGVTVTARAASRDAAPQQL-TPVTAIG---
MAB_1304|M.abscessus_ATCC_1997 IWRIDRPWPLAWAGLVDIVAAIATLTWMAVVGRRSGHLGRLPWRHV----
** . * .:. **.
Mflv_2968|M.gilvum_PYR-GCK A-
Mvan_3543|M.vanbaalenii_PYR-1 A-
MSMEG_4247|M.smegmatis_MC2_155 AG
TH_1105|M.thermoresistible__bu --
MUL_3536|M.ulcerans_Agy99 --
MMAR_3225|M.marinum_M --
Mb2203|M.bovis_AF2122/97 --
Rv2181|M.tuberculosis_H37Rv --
MLBr_00893|M.leprae_Br4923 --
MAV_2312|M.avium_104 --
MAB_1304|M.abscessus_ATCC_1997 --