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MSAWRAPEVGSRLGRRVLWCLLWLLAGVALGYVAWRLFGHTPYRIDIDIYQMGARAWLDGRPLYGGGVLF HTPIGLNLPFTYPPLAAVLFSPFAWLQMPAASVAITVLTLVLLIASTAIVLTGLDAWPTSRLVPAPARLR RLWLAVLIVAPATIWLEPISSNFAFGQINVVLMTLVIVDCFPRRTPWPRGLMLGLGIALKLTPAVFLLYF LLRRDGRAALTALASFAVATLLGFVLAWRDSWEYWTHTLHHTDRIGAAALNTDQNIAGALARLTIGDDER FALWVAGSLLVLAATIWAMRRVLRAGEPTLAVICVALFGLVVSPVSWSHHWVWMLPAVLVIGLLGWRRRN VALAMLSLAGVVLMRWTPIDLLPQHRETTAVWWRQLAGMSYVWWALAVIVVAGLTVTARMTPQRSLTRGL TPAPTAS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2181 | - | - | 100% (427) | Probable conserved integral membrane protein |
| M. tuberculosis H37Rv | Rv1159 | pimE | 4e-35 | 30.53% (380) | mannosyltransferase |
| M. tuberculosis H37Rv | Rv0051 | - | 3e-07 | 25.34% (367) | transmembrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2203 | - | 0.0 | 100.00% (427) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_2968 | - | 1e-150 | 64.96% (411) | putative integral membrane protein |
| M. leprae Br4923 | MLBr_00893 | - | 0.0 | 80.14% (428) | hypothetical protein MLBr_00893 |
| M. abscessus ATCC 19977 | MAB_0096 | - | 2e-42 | 37.86% (309) | hypothetical protein MAB_0096 |
| M. marinum M | MMAR_3225 | - | 0.0 | 80.05% (426) | hypothetical protein MMAR_3225 |
| M. avium 104 | MAV_2312 | - | 0.0 | 78.76% (386) | hypothetical protein MAV_2312 |
| M. smegmatis MC2 155 | MSMEG_4247 | - | 1e-150 | 63.22% (416) | integral membrane protein |
| M. thermoresistible (build 8) | TH_1105 | - | 1e-149 | 65.32% (395) | Probable conserved integral membrane protein |
| M. ulcerans Agy99 | MUL_3536 | - | 0.0 | 79.81% (426) | hypothetical protein MUL_3536 |
| M. vanbaalenii PYR-1 | Mvan_3543 | - | 1e-152 | 67.35% (389) | putative integral membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2968|M.gilvum_PYR-GCK ---MSNRRSP-GGAGWGPRLLWRLFQLLTLAALVIAASRLLGHVPYRIDI
Mvan_3543|M.vanbaalenii_PYR-1 ---MSNRQSP-GGAGWKPTLAWRLFQLLTFAALAAAAWRLLGHVPYRIDI
MSMEG_4247|M.smegmatis_MC2_155 MLEMSKRQSP-RGAGLAPTIAWRVFQLLTLAGVLWVGWRLLGRVPYRIDI
TH_1105|M.thermoresistible__bu -----------------------MFQLITLAALIWAGWRLLGHLPYRIDI
Rv2181|M.tuberculosis_H37Rv ---MSAWRAPEVGSRLGRRVLWCLLWLLAGVALGYVAWRLFGHTPYRIDI
Mb2203|M.bovis_AF2122/97 ---MSAWRAPEVGSRLGRRVLWCLLWLLAGVALGYVAWRLFGHTPYRIDI
MMAR_3225|M.marinum_M ---MSTWRSPDVGSRLGRFSVWYLLWLVAAAALGYVVWRLFGHIPYRIDI
MUL_3536|M.ulcerans_Agy99 ---MSTLRSPDVGSRLGRVSVWYLLWLVAAAALGYVAWRLFGHIPYRIDI
MLBr_00893|M.leprae_Br4923 ---MSRQQTPEVGNKHRQIGRCCLLWLLAVTALGQVAWQLLGHTPYRIDI
MAV_2312|M.avium_104 ---------------------------------------MFGHTPYRIDI
MAB_0096|M.abscessus_ATCC_1997 -MHSWGGEKRLPRSAVVGALVAAVLAMVVHDHLVPFDVRFFGLTQNGYDL
::* *:
Mflv_2968|M.gilvum_PYR-GCK DVYRMGGRAWLDGRSLYADGAMFQTRGGLELPFTYPPLAAVAFSPFAMLS
Mvan_3543|M.vanbaalenii_PYR-1 DVYRMGGRAWLDGQSLYADGAMFQTRGGLELPFTYPPLAAVAFAPFALLS
MSMEG_4247|M.smegmatis_MC2_155 DVYRMGGRAWLDGRPLYADGAIFHTQGGLDLPFTYPPLAAIAFAPFAWLS
TH_1105|M.thermoresistible__bu DVYRMGGRAWLDGDPLYADGAIFETRAGLNLPFTYPPLAAVAFAPFAWLS
Rv2181|M.tuberculosis_H37Rv DIYQMGARAWLDGRPLYGGGVLFHTPIGLNLPFTYPPLAAVLFSPFAWLQ
Mb2203|M.bovis_AF2122/97 DIYQMGARAWLDGRPLYGGGVLFHTPIGLNLPFTYPPLAAVLFSPFAWLQ
MMAR_3225|M.marinum_M DIYQMGGQAWLDGRPLYSGDVKFHTPIGLDLPFTYPPLSAVVFSPFAWLH
MUL_3536|M.ulcerans_Agy99 DIYQMGGQAWLDGRPLYSGDVKFHTPIGLDLPFTYPPLSAVVFSPFAWLH
MLBr_00893|M.leprae_Br4923 DIYQMGGQAWLDGRPLYSGDVLFHTPIGLNLPFTYPPLAAIAFCPFAWLH
MAV_2312|M.avium_104 DVYQMGARAWMDGRPLYRGDVLFHTPI-VDLPFTYPPLAAIVFCPFAWMH
MAB_0096|M.abscessus_ATCC_1997 DTYRAAVRGLWDGKRLYEAPALN------QAWFVYPPFATLVLAPLAWAS
* *: . :. ** ** . : *.***:::: :.*:*
Mflv_2968|M.gilvum_PYR-GCK LEAASLAITATTLVLLLVSTVIVLTRLDVWPTTGVTREPAWVRRCWLAAA
Mvan_3543|M.vanbaalenii_PYR-1 LEAASVAITLTTLILLLVSTVIVLTRLDVWPSTRVTSEPAWLRRCWLAAA
MSMEG_4247|M.smegmatis_MC2_155 LPLASSAITATTLVLLIVATTIVLTRLDVWPHTTVTSEPAWMRRAWLAAA
TH_1105|M.thermoresistible__bu LEAAAVAITLTTLVLLVVATVIVLTRLDVWPDTAMTTEPAWLRRSWLAAA
Rv2181|M.tuberculosis_H37Rv MPAASVAITVLTLVLLIASTAIVLTGLDAWPTSRLVPAPARLRRLWLAVL
Mb2203|M.bovis_AF2122/97 MPAASVAITVLTLVLLIASTAIVLTGLDAWPTSRLVPAPARLRRLWLAVL
MMAR_3225|M.marinum_M MPAASVAITFLTLVVLIASTVVVLTALDVWPDSEQLPGPAWLRRLWLAVI
MUL_3536|M.ulcerans_Agy99 MPAASVAITFLTLVVLTASTVVVLTALDVWPNSEQLPGPAWLRRLWLAVI
MLBr_00893|M.leprae_Br4923 MPAASVAITLTTLMLLIVSTIIVLTRLDVWAMSRAVPGPAWLRRLWLAVI
MAV_2312|M.avium_104 MPTASVAITALTLVLLVVSTVIVLARLDVWSTSALLPGPAWLRRWWLAVV
MAB_0096|M.abscessus_ATCC_1997 FEVAKWMLLILSLSALALIAWRILRLAGVRADS----------RLGLASA
: * : :* * : :* .. . : * **
Mflv_2968|M.gilvum_PYR-GCK IVAPAVIFCEPIRANFDFGQINVVLMTLVLADCVPRRTPCPRGVLLGLAI
Mvan_3543|M.vanbaalenii_PYR-1 IVAPAVLYLEPLRANFDFGQINVVLMTLVIADCVPRRTPWPRGVLLGVAI
MSMEG_4247|M.smegmatis_MC2_155 MVAPAVIYLEPIRSNFEFGQINVVLMTLVIADCVPRRTPWPRGLLLGLAI
TH_1105|M.thermoresistible__bu IVAPAIILLEPIRSNFEFGQINVVLMTLVIADCVPRRTPWPRGALLGVAI
Rv2181|M.tuberculosis_H37Rv IVAPATIWLEPISSNFAFGQINVVLMTLVIVDCFPRRTPWPRGLMLGLGI
Mb2203|M.bovis_AF2122/97 IVAPATIWLEPISSNFAFGQINVVLMTLVIVDCFPRRTPWPRGLMLGLGI
MMAR_3225|M.marinum_M IVAPASLWLEPISSNFAFGQINAVLMTLVILDCFPRRTPWPRGLLLGLGI
MUL_3536|M.ulcerans_Agy99 IVAPASLWLEPISSNFAFGQINAVLMTLVILDCFPRRTPWPRGLLLGLGI
MLBr_00893|M.leprae_Br4923 IVSPAAIWLEPISSNFAFGQINVVLMTLVIADCVPRRTPWPRGLMLGLGI
MAV_2312|M.avium_104 VAAAATIWLEPISSNFAFGQINVVLMTLVIADCLPRRTPWPRGLLLGLGM
MAB_0096|M.abscessus_ATCC_1997 ALAAIVVDVEPVQATLWWGQINILLMAVVLLDLLGPAQSRWRGVGLGLAA
:. : **: :.: :**** :**::*: * . . ** **:.
Mflv_2968|M.gilvum_PYR-GCK AVKLTPAVFLLYFLLRRDTRALLVTAASVVVATLAGFAFAWSDSWEYWTE
Mvan_3543|M.vanbaalenii_PYR-1 AVKLTPAVFLLYFLLRRDVRALLVTAASAVVATLAGFALAWRDSWEYWLE
MSMEG_4247|M.smegmatis_MC2_155 ALKLTPAVFLLYFLLRRDIHTLLRTAATAVVASLAGFALAWSDSVEYWTE
TH_1105|M.thermoresistible__bu ALKLTPAVFLLYFLLRRDGRALITASVTAVLATLAGFALAWRDSWEYWTH
Rv2181|M.tuberculosis_H37Rv ALKLTPAVFLLYFLLRRDGRAALTALASFAVATLLGFVLAWRDSWEYWTH
Mb2203|M.bovis_AF2122/97 ALKLTPAVFLLYFLLRRDGRAALTALASFAVATLLGFVLAWRDSWEYWTH
MMAR_3225|M.marinum_M ALKLTPAVFLLYFLLRRDNRAALTAVASFVVATLAGFALAWRDSWEYWTD
MUL_3536|M.ulcerans_Agy99 ALKLTPAVFLLYFLLRRDNRAALTAVASFVVATLAGFALAWHDSWEYWTD
MLBr_00893|M.leprae_Br4923 ALKLTPAVFLLYFVLRRDNRAALTSWASFAGATLVGFVLAWRDSWEYWTH
MAV_2312|M.avium_104 ALKLTPAVFLLYFLLRRDHRAVLTALASFAGATLLGFVLAYTDSWEYWTH
MAB_0096|M.abscessus_ATCC_1997 GIKLTPLIFLPYLLCTRQWRAATHALGTMAATVALTWPLLPRDSEWFWSH
.:**** :** *:: *: :: : : . : : : ** :* .
Mflv_2968|M.gilvum_PYR-GCK TVRNTDRIGTATLNTNQNIAGALARLGLGEDARFLLWVALCFAVLALTVW
Mvan_3543|M.vanbaalenii_PYR-1 TVRNTDRIGTATLNTNQNIAGVLARLGLGEGERFVVWTVLCFAVLGLTVW
MSMEG_4247|M.smegmatis_MC2_155 TVRNTDRIGTATLNTNQNIAGALARLGLGESPRFILWVLACFAVLALTVW
TH_1105|M.thermoresistible__bu TVSNTDRIGTATLNTNQNIAGALARLGLDEDTRFLLWVLACFAVLALTVW
Rv2181|M.tuberculosis_H37Rv TLHHTDRIGAAALNTDQNIAGALARLTIGDDERFALWVAGSLLVLAATIW
Mb2203|M.bovis_AF2122/97 TLHHTDRIGAAALNTDQNIAGALARLTIGDDERFALWVAGSLLVLAATIW
MMAR_3225|M.marinum_M TLLHTDRIGSAALNTDQNIAGALARLPIGEHASHLMWVLLSLGVLAVTVW
MUL_3536|M.ulcerans_Agy99 TLLHTDRIGSAALNTDQNIAGALARLPIGEHASHLLWVLLSLGVLAVTVW
MLBr_00893|M.leprae_Br4923 TVHNTERIGAAALNTDQNIAGALARLGLGEHERFLLWAAGCLLVLAATAW
MAV_2312|M.avium_104 TVHHTDRIGSASLNTDQNIAGALARLGLAQQPRSLLWVAASLLVLAVTVW
MAB_0096|M.abscessus_ATCC_1997 -LGDTAHISRIDHLANQTINGFLARYFFPQPRPEWLWIALSLLVLAAGLA
: .* :*. ::*.* * *** : : :* .: **.
Mflv_2968|M.gilvum_PYR-GCK AARRALR-------ADQPVLALISVAMFGLVVSPVSWSHHWVWMLPTVVV
Mvan_3543|M.vanbaalenii_PYR-1 AARRALR-------AEQPVLALICVAMFGLVVSPVSWSHHWVWALPTVLV
MSMEG_4247|M.smegmatis_MC2_155 AARRALRGDTADQTTEAPVLALVCVALFGLVVSPVSWSHHWVWMLPVLVV
TH_1105|M.thermoresistible__bu AVRRVLR--SRVCADEASVLALICVAMFGLVVSPVSWSHHWVWALPAVLV
Rv2181|M.tuberculosis_H37Rv AMRRVLR-------AGEPTLAVICVALFGLVVSPVSWSHHWVWMLPAVLV
Mb2203|M.bovis_AF2122/97 AMRRVLR-------AGEPTLAVICVALFGLVVSPVSWSHHWVWMLPAVLV
MMAR_3225|M.marinum_M AMRRVLR-------AEEPSLAVICVALFGLVVSPVSWSHHWVWMLPAVVV
MUL_3536|M.ulcerans_Agy99 AMRRVLR-------AEEPSLAVICVALFGLVVSPVSWSHHWVWMLPAVVV
MLBr_00893|M.leprae_Br4923 AMLRVLR-------AGEPMLAVICVALFGLVVSPVSWSHHWVWMLPAVLV
MAV_2312|M.avium_104 AMRRVLR-------ADEPTLALVCVALFGLVVSPVSWSHHWVWVLPTVLV
MAB_0096|M.abscessus_ATCC_1997 VAVWAHR-------RGEHALALILVGLTGCAVSPFSWAAHWVWFAPAIVW
. . * **:: *.: * .***.**: **** *.::
Mflv_2968|M.gilvum_PYR-GCK TAVLAVRLR-HALLGAVATLGLVLMVWSPITLLPEHRETTAALWR-----
Mvan_3543|M.vanbaalenii_PYR-1 TAVLAVRLR-HVALAVVSAAGLALMVWTPITLLPEHRETTASLWR-----
MSMEG_4247|M.smegmatis_MC2_155 TAVLAYRRR-SVWFTALTAAGLALTVWTPITLLPEHRETTASLWR-----
TH_1105|M.thermoresistible__bu AAVVSARHR-VRALGVTAAAGVALLVWTPIRLLPENEEMTASLWR-----
Rv2181|M.tuberculosis_H37Rv IGLLGWRRR-NVALAMLSLAGVVLMRWTPIDLLPQHRETTAVWWR-----
Mb2203|M.bovis_AF2122/97 IGLLGWRRR-NVALAMLSLAGVVLMRWTPIDLLPQHRETTAVWWR-----
MMAR_3225|M.marinum_M TGVLAWRRR-NVALAVVTIAGLALMRWSPIDLLPKHREATAAWWR-----
MUL_3536|M.ulcerans_Agy99 TGVLAWRRR-NVALAVVTIAGLALMRWSPIDLLPKHREATAAWWR-----
MLBr_00893|M.leprae_Br4923 TGILSWRRQ-NVAVAVISAAGVALMRWTPIGLLPQHQETTAVWWR-----
MAV_2312|M.avium_104 TGVLGWRRR-NAALLVLSVVGVALMRWTPIDLLPKHHEASAVWWR-----
MAB_0096|M.abscessus_ATCC_1997 LVAKACTTQGPWSQGWIYRAAGLLALVFMWTLHRPGRGHTTIYFSGVYWN
. : . * * . :: :
Mflv_2968|M.gilvum_PYR-GCK ------QLVGGSYLWWALAVIVAIGTVTLHRDTTPGVDAREPG-AEPGTE
Mvan_3543|M.vanbaalenii_PYR-1 ------QLVGGSYLWWALAVIVVSATVTLPR---PGRDAPGLGAAQPATN
MSMEG_4247|M.smegmatis_MC2_155 ------QLAGGSYVWWAFAVIVVIGLVSSSR--THTGDAHETDEPLVPLA
TH_1105|M.thermoresistible__bu ------QLLGGSYVWWALVLIVVIGALGSGS-----ARPRPVDAERVPTG
Rv2181|M.tuberculosis_H37Rv ------QLAGMSYVWWALAVIVVAGLTVTARMTPQRSLTRGL-TPAPTAS
Mb2203|M.bovis_AF2122/97 ------QLAGMSYVWWALAVIVVAGLTVTARMTPQRSLTRGL-TPAPTAS
MMAR_3225|M.marinum_M ------QLAGMSYVWWALAVIVVAGLTVTTRMTMQRPAEPGR-TPVPAAR
MUL_3536|M.ulcerans_Agy99 ------QLAGMSYVWWALAVIVVAGLTVTTRMTMQRPAEPDR-TPAPAAR
MLBr_00893|M.leprae_Br4923 ------QLAGMSYVWWALAVIVATGLTVTTRVTSQDSATQTLLTPVSTAS
MAV_2312|M.avium_104 ------QLAGMSYVWWALAVIVAAGVTVTARAASRDAAPQQL-TPVTAIG
MAB_0096|M.abscessus_ATCC_1997 FLDLRPFWAGQLVSGWYPLVFLCFTIATASWLRLSTGGCAEPDELATLTA
* * :::
Mflv_2968|M.gilvum_PYR-GCK VLKA--------------
Mvan_3543|M.vanbaalenii_PYR-1 GVKA--------------
MSMEG_4247|M.smegmatis_MC2_155 RGEAG-------------
TH_1105|M.thermoresistible__bu G-----------------
Rv2181|M.tuberculosis_H37Rv ------------------
Mb2203|M.bovis_AF2122/97 ------------------
MMAR_3225|M.marinum_M ------------------
MUL_3536|M.ulcerans_Agy99 ------------------
MLBr_00893|M.leprae_Br4923 ------------------
MAV_2312|M.avium_104 ------------------
MAB_0096|M.abscessus_ATCC_1997 DIEDYPPEIFDEELAVRA