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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_4487 | - | - | 100% (463) | virulence factor mce family protein |
M. thermoresistible (build 8) | TH_2981 | - | e-132 | 59.26% (378) | PUTATIVE virulence factor Mce family protein |
M. thermoresistible (build 8) | TH_3627 | - | e-123 | 53.53% (411) | PUTATIVE virulence factor Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3525c | lprN | 9e-60 | 35.96% (356) | MCE-family lipoprotein LprN |
M. gilvum PYR-GCK | Mflv_2512 | - | 1e-145 | 58.21% (469) | virulence factor Mce family protein |
M. tuberculosis H37Rv | Rv1970 | lprM | 6e-78 | 45.02% (331) | MCE-family lipoprotein LprM |
M. leprae Br4923 | MLBr_02593 | lprK | 1e-52 | 32.93% (331) | putative lipoprotein |
M. abscessus ATCC 19977 | MAB_4149c | - | 2e-66 | 39.94% (328) | MCE-family protein LprN |
M. marinum M | MMAR_4706 | - | 1e-135 | 59.41% (409) | MCE family lipoprotein |
M. avium 104 | MAV_2536 | - | 1e-80 | 42.40% (375) | virulence factor Mce family protein |
M. smegmatis MC2 155 | MSMEG_4786 | - | 1e-172 | 66.31% (472) | virulence factor mce family protein |
M. ulcerans Agy99 | MUL_2866 | lprM | 6e-81 | 46.67% (330) | MCE family lipoprotein LprM |
M. vanbaalenii PYR-1 | Mvan_4146 | - | 1e-145 | 57.08% (466) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment Rv1970|M.tuberculosis_H37Rv -----MRIG------------LTLVMIAAVVASCGWRGLNSLPLPGTQGN MUL_2866|M.ulcerans_Agy99 -----MRVRQRRRVAPRLATVLVTMVTLAAVSGCGWRGLNSLPLPGTEGN MAV_2536|M.avium_104 -----MSQSPLRR---RVMAALLAAVALATLSGCGFRGLNSFNLPGTKGG Mb3525c|M.bovis_AF2122/97 -----MNRIWLR-------AIIL-TASSALLAGCQFGGLNSLPLPGTAGH MAB_4149c|M.abscessus_ATCC_199 -----MSRNVLR-------AAVMGVGVAVVVSGCQFNGLNSLNLPGTAGH TH_4487|M.thermoresistible__bu --------MMRG-------VVAVGACVALTVSGCGFQGVNSLPLPGAVGR MSMEG_4786|M.smegmatis_MC2_155 ---MRIRKRIRL-------AVAAGTCVALTASGCAFQGVNSLPLPGAEGR MMAR_4706|M.marinum_M MTASTATPALRR-------LFVIGCCVMLAVTGCAFNGLNSLPLPGAVGR Mflv_2512|M.gilvum_PYR-GCK -----MMRSVKS-------WAAVGCAVAVTLSGCAFEGVNSLPLPGAEGR Mvan_4146|M.vanbaalenii_PYR-1 -----MIRGVKQ-------LTVLGCSAALSLSGCAFQGVNSLPLPGAVGR MLBr_02593|M.leprae_Br4923 -MRRAMSVVHTSRVRHQTWRGLVMLVAALLLSSCGWRGISNVSIPGGPGS :.* : *:... :** * Rv1970|M.tuberculosis_H37Rv GPGSFAVQAQLPDVNNIQPNSRVRVADVTVGHVTKIERQG-----WHALV MUL_2866|M.ulcerans_Agy99 GPGSFVIQAQMPDVNNIQPNSRVRVADVTVGHVARIERQG-----WHALV MAV_2536|M.avium_104 GPGAYTIRAQMPDVQNLQRNSRVRVNDVTVGNVIDIELQG-----WNALV Mb3525c|M.bovis_AF2122/97 GEGAYSVTVEMADVATLPQNSPVMVDDVTVGSVAGIVAVQRPDGSFYAAV MAB_4149c|M.abscessus_ATCC_199 GSRSYTVTVELPDVTTLPQNSPVMVDDVTVGSVSGIDAFQKPDGSWYAGV TH_4487|M.thermoresistible__bu GPGAETYTVEIENVATLEPNSPVMIGDVVVGSVRSMTVQD-----WHAKV MSMEG_4786|M.smegmatis_MC2_155 GADSVVYHVEIANVATLEPNSPVMMNDVVVGSVRRLAVRD-----WHADV MMAR_4706|M.marinum_M GPGASVYHVEIANVGTLEANSPVMLNDVIVGSISKMTVRG-----WHADV Mflv_2512|M.gilvum_PYR-GCK GGDAVTYHIQVPNVATLESNSPVMIDDVVVGSVGKMTVQN-----WHADV Mvan_4146|M.vanbaalenii_PYR-1 GPDAVSYNVQVPNVATLESNSPVMIDDVVVGSVGKMTVQN-----WHADV MLBr_02593|M.leprae_Br4923 GKGAYTIYVQVPDTLAINGNSKVMVADVTVGSIRAINLKN-----WVATL * : :: :. : ** * : ** ** : : : * : Rv1970|M.tuberculosis_H37Rv TMRLDGDVDLPANATAKIGTTSLLGSYHIELAPPKGEARQGKLRDGSLIA MUL_2866|M.ulcerans_Agy99 TIRLDAGVALPANATARIGTTSLLGSYHIELAAPKHDAPQGRLRKGSLIP MAV_2536|M.avium_104 TMTIDGDVDLPANATATLGQTSLLGSVHVELAPPAGVAPQGKLKNGSLIP Mb3525c|M.bovis_AF2122/97 KLDLDKNVLLPANAVAKVSQTSLLGSLHVELAPPTDRPPTGRLVDGSRIT MAB_4149c|M.abscessus_ATCC_199 KVSLEPEVHLPANAVAKVAQTSLLGSQHIELAAPVGEPAVGKLTGGATIP TH_4487|M.thermoresistible__bu EISVEPGVEVPANAVASVGQTSLLGSMHLALDPPPGERPQGRLAPGSVIR MSMEG_4786|M.smegmatis_MC2_155 EFSVEPGVVVPANAVATIGQTSLLGSMHLALNPPLGQEPQGRLTPGGTIP MMAR_4706|M.marinum_M EISVRRGAVIPDNAVASVGQTSLLGSMHLALNSPLGQVSDQRLQPGSTIP Mflv_2512|M.gilvum_PYR-GCK EVSIKPDVVIPANAVATVGQTSLLGSMHLALNPPLGESPSGRLQPGSTLP Mvan_4146|M.vanbaalenii_PYR-1 EISVKPDVVIPANAVATVGQTSLLGSMHLALNPPLGDEPKGRLQPGSTLP MLBr_02593|M.leprae_Br4923 TLGLNKDVQLPKNTTAKIGQTSLLGSQHVELAAPAN-PSLELLKNGDTIP . : . :* *:.* :. ****** *: * .* * * : Rv1970|M.tuberculosis_H37Rv LSHGSAYPSTEQTLAALSLVLNGGGLGQVQDITEALSTAFAGREHDLRGL MUL_2866|M.ulcerans_Agy99 LSRGGAYPSTEQTLAALSLVLNGGGLGQVQDITEALSTAFRGREHEVRSL MAV_2536|M.avium_104 LSSAGAYPSTERTLAAVSLLLNGGGLGQVQDITKTLSTAFSGREQDLRNL Mb3525c|M.bovis_AF2122/97 EANTDRFPTTEEVFSALGVVVNKGNVGALEEIIDETHQAVAGRQAQFVNL MAB_4149c|M.abscessus_ATCC_199 LSRTGKYPSTEEVLSALSVVVNKGNLGALQDITDETYNLFKGRTGNLTQV TH_4487|M.thermoresistible__bu LDDSSTYPTTEQTLASLAAVVNGGGLGQIGDVIHNMSGALNGREQQIRDL MSMEG_4786|M.smegmatis_MC2_155 LNSASTYPTTEQTLSSLAAVVNGGGLGQIGEVIHNFSVALDGREADFRDL MMAR_4706|M.marinum_M LSRSSTYPSTEQTLSSLSVILNAGGLGQIGDIIHNFTAALSGRTSDIRDL Mflv_2512|M.gilvum_PYR-GCK LNESSTYPTTEQTLSSLSTVANGGGLGQIGDIIHNMSTGLAGREDDAREL Mvan_4146|M.vanbaalenii_PYR-1 LNASSTYPTTEQTLASLSTVANGGGLGQIGDIVHNMNTALSGREPEVREL MLBr_02593|M.leprae_Br4923 LKNSSVFPTTEQTLASLSLILRGGGIPNLETLTNEVFNIFHGRADQIHAF . :*:**..::::. : . *.: : : . . ** : . Rv1970|M.tuberculosis_H37Rv IGQLDTFTAYLNNQSGDIIAATDSLNRLVGKFADQQPVFDRALATIPDAL MUL_2866|M.ulcerans_Agy99 IAQLDSFTATLDDQSDDIIEATESLNRLVGKFAEQQPVLDRALATIPDAL MAV_2536|M.avium_104 LNQLDTFVGYLNDQKSDIIAATDHLNNLVGQFADQKPIIDKALKTIPQAL Mb3525c|M.bovis_AF2122/97 VPRLAELTAGLNRQVHDIIDALDGLNRVSAILARDKDNLGRALDTLPDAV MAB_4149c|M.abscessus_ATCC_199 LPKLATLISSLNSQRDDIISAIEGIDKFSRVLAEHKESLGRAIDSIEPAL TH_4487|M.thermoresistible__bu LNRLDTFVGTLDAQRDNIVSSIESLNRLAARFAGERDDITRALERVPPAI MSMEG_4786|M.smegmatis_MC2_155 LTRLDNFVGTLDAQRDNIVSSIDSLNRLASTFAGQSEEITRALNKIPPAM MMAR_4706|M.marinum_M LVRLDRFVGTFDEQRDNLVASIQALNRLAGTLAGQRDVITQALQKIPPAL Mflv_2512|M.gilvum_PYR-GCK LQRLDNFVGVLAEQREDIVASIQQLRRVAGTFANQQQVIDRALTEIPPAI Mvan_4146|M.vanbaalenii_PYR-1 LTRLDNFVGVLAEQRENIIASIQQLRRVAGTFANQREVIDRALKEIPPAI MLBr_02593|M.leprae_Br4923 LTKLDTFASQLNQQRDDITHAIDSTNRLLTYVGGRSDVLDQILTDIPPLI : :* : . : * :: : : .. .. : : : : : Rv1970|M.tuberculosis_H37Rv AVLADERDTLVEAAEQLSKFSALTVDSVNKTTANLVTELRQLGPVLESLA MUL_2866|M.ulcerans_Agy99 AVLNDERDKLVTAADQLSKFSALTADSVNKTKANLVSELRQLGPVLESLA MAV_2536|M.avium_104 TVLKDERENLANALGEVGQLSALAADSVNKTKENLIKELKDLGPVLQSLA Mb3525c|M.bovis_AF2122/97 RVLNQNRDHIVDAFAALKRLTMVTSHVLAETKVDFGEDLKDLYSIVKALN MAB_4149c|M.abscessus_ATCC_199 KVLNENRANIIEAFRSVGNLAKITDRVLRTTKDDIVADLKGLYPVVRALA TH_4487|M.thermoresistible__bu EVLVRERPRLTAALERLGTFSDTTTRFVNDSQADLVRNLENLEPALKALA MSMEG_4786|M.smegmatis_MC2_155 DVLIQERPRFTTALQKLGTFGSTAHQLVNESQDDLVRNLRNLEPAIKALA MMAR_4706|M.marinum_M DVLIRERPRITAALDKLGTFSDTATRLVNDAGSDLVQNLQNLGPTISALA Mflv_2512|M.gilvum_PYR-GCK DVLIQERPQFTTALDRLGTFSDTATQLVNDAGDDLVKNLENLGPILGALA Mvan_4146|M.vanbaalenii_PYR-1 DVLIRERPNFTTALDRLGQFSNTATQLVNDAGDDLVKNLENLGPVLGALA MLBr_02593|M.leprae_Br4923 KHFADTKNLLINAVGSVGQLSQAVDQYLSEARGPLHTDLQALACPLRELG : : : * : : . : : : :*. * : * Rv1970|M.tuberculosis_H37Rv NSGPALTRSLSLLATFPFPNETFQNFQRGEYANLTAIVDLTLSRIDQGLL MUL_2866|M.ulcerans_Agy99 NAGPSLTRSLSLLATFPFPNETFQNFQRGDYANLTAIVDLTLSRIDQGLL MAV_2536|M.avium_104 DAGPALTRSLGFLGTFPFPAETLSKWIRGDYANLTAVIDLTLSRLDASFL Mb3525c|M.bovis_AF2122/97 DDRKDFVTSLQLLLTFPFPNFGIKQAVRGDYLNVFTTFDLTLRRIGETFF MAB_4149c|M.abscessus_ATCC_199 ENRDVLIDSLDLLPTFPFSTKYLRNAVRGDYLNVFVTFDLTARRLGETLF TH_4487|M.thermoresistible__bu DVGPSLNSVLEFAVHFPFTQNFIDRAIRGDYYNLFAIVDFTIPRLKRTLF MSMEG_4786|M.smegmatis_MC2_155 DVGPDLAGVLEYAGHFPFTQSFIDRAIRGDYWNLFATIDLTIPRLKRSLM MMAR_4706|M.marinum_M DIGPDLDAAIAYAPTFPFTQGFIDRYIRGDYVNGYFIIDLTNAGLRKSIL Mflv_2512|M.gilvum_PYR-GCK DVGPDLNLALLWTSAFPYGPTFADRVTKGDYINLYAIFDITYPRLKKTLL Mvan_4146|M.vanbaalenii_PYR-1 DIGPDLNEAVLWASAFPYGPTFADRITRGDYINLYAIFDLTYPRLKKTLL MLBr_02593|M.leprae_Br4923 RGAPYFIGAMKLILTQPYDVDTVPKIMRGDYQNVSLTLDVTYSAMDNAVL : : *: . :*:* * .*.* : .: Rv1970|M.tuberculosis_H37Rv TGTRWECHLTQLELQWG---RTIGQFPS---------------------- MUL_2866|M.ulcerans_Agy99 TGTRWECHLTELELQWG---RTIGQFPS---------------------- MAV_2536|M.avium_104 TGTRFECNLTELELQWG---RTIGQLPS---------------------- Mb3525c|M.bovis_AF2122/97 TTAYFDPNMAHMDEILNPPDFLIGELAN---------------------- MAB_4149c|M.abscessus_ATCC_199 TTSFFDPNMQHFNDVVNPPEWLIGSMAN---------------------- TH_4487|M.thermoresistible__bu LGTRWAQEGAQLVPAPGDPQYLQYTYDPLRLGVDPP-PPQFVPPLGDEVF MSMEG_4786|M.smegmatis_MC2_155 LGTRWEQEGAQLVPAPGDPYYLNYTYDPLKAGVETPGPASFPPPFAD--- MMAR_4706|M.marinum_M LGTHWGRLGAEGVPAPGDPEYLQFKFG----------------------- Mflv_2512|M.gilvum_PYR-GCK LGTRWGDENAKLIPAPGDPYYLNYSYDPLKIGVAP--------------- Mvan_4146|M.vanbaalenii_PYR-1 AGTRWGDQNAKLIPAPGDPYYLNYAYNPMMVGITP--------------- MLBr_02593|M.leprae_Br4923 TGTGLSGALRALEQSFGRDPETMIPDVR---------------------- : . Rv1970|M.tuberculosis_H37Rv ----------------------PCTAGYRGTPGNPLTIAYRWDQGP---- MUL_2866|M.ulcerans_Agy99 ----------------------PCTAGYRGTPGNPLTVPYHWDQGP---- MAV_2536|M.avium_104 ----------------------PCTGGGPYNPGNPLVVPYHFDQGR---- Mb3525c|M.bovis_AF2122/97 ----------------------LSGQAADPFKIPPGTAS---GQ------ MAB_4149c|M.abscessus_ATCC_199 ----------------------LNGKETSPFDLPAPAAPQGGGR------ TH_4487|M.thermoresistible__bu PPAVPPEPPQAATAEQEALPLPPITEDVGPLLPAAPPAVVNFPGGPVTVR MSMEG_4786|M.smegmatis_MC2_155 -PPVPAAPVDQTTLPLPEAPPGPPPAYAGPVLPVAPPAPMTLPGVPAPVT MMAR_4706|M.marinum_M -APIPPGPPPADAPPPGDPAPGPPPDSAVPIPGATPAEAAPTDGGP---- Mflv_2512|M.gilvum_PYR-GCK -PPAEAIPAPAEG-AAATPALPPMSEPLLPVTPPPPAAPWLPQSQPITSG Mvan_4146|M.vanbaalenii_PYR-1 -PPEEALPPPAQG-GAPSSLTGVPAQPILPVVPPPPAAPWLPQAQPMAGD MLBr_02593|M.leprae_Br4923 -----------------------YTTNPNDAPGGPLVERADRRC------ . Rv1970|M.tuberculosis_H37Rv --------------------------------------- MUL_2866|M.ulcerans_Agy99 --------------------------------------- MAV_2536|M.avium_104 --------------------------------------- Mb3525c|M.bovis_AF2122/97 --------------------------------------- MAB_4149c|M.abscessus_ATCC_199 --------------------------------------- TH_4487|M.thermoresistible__bu PTPPAPDGSTPIFAG-HPAQPPSPETAPS-----SGGGG MSMEG_4786|M.smegmatis_MC2_155 -TPGDP---TQIFAGPYGDQPNPPTEAPAPAQPTTGGGG MMAR_4706|M.marinum_M --------------------------------------- Mflv_2512|M.gilvum_PYR-GCK ----------NIFAGPYGAEAAP--APVPPAAPTPGGGG Mvan_4146|M.vanbaalenii_PYR-1 ----------QIFAGPFGAPTPPPVAPPAPSVPTPGGGG MLBr_02593|M.leprae_Br4923 ---------------------------------------