For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3627 | - | - | 100% (405) | virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_4487 | - | e-123 | 53.53% (411) | PUTATIVE virulence factor mce family protein |
| M. thermoresistible (build 8) | TH_2981 | - | e-120 | 59.77% (348) | PUTATIVE virulence factor Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0179 | lprK | 3e-47 | 33.43% (338) | MCE-family lipoprotein LprK |
| M. gilvum PYR-GCK | Mflv_4534 | - | 1e-119 | 58.47% (354) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv1970 | lprM | 2e-61 | 38.19% (343) | MCE-family lipoprotein LprM |
| M. leprae Br4923 | MLBr_02593 | lprK | 4e-43 | 30.23% (344) | putative lipoprotein |
| M. abscessus ATCC 19977 | MAB_4149c | - | 7e-55 | 39.35% (310) | MCE-family protein LprN |
| M. marinum M | MMAR_4706 | - | 1e-108 | 54.03% (372) | MCE family lipoprotein |
| M. avium 104 | MAV_2536 | - | 2e-69 | 43.71% (302) | virulence factor Mce family protein |
| M. smegmatis MC2 155 | MSMEG_2859 | - | 1e-120 | 59.72% (355) | virulence factor Mce family protein |
| M. ulcerans Agy99 | MUL_3922 | lprM_1 | 3e-65 | 39.17% (337) | MCE family lipoprotein LprM |
| M. vanbaalenii PYR-1 | Mvan_2855 | - | 1e-124 | 60.22% (357) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4534|M.gilvum_PYR-GCK --------MTRPTVRRTRRWAAAACCVALTATGCSFDGLNSLPLPGTVGT
Mvan_2855|M.vanbaalenii_PYR-1 --------MTSP-GKPVRRWAATACCVALTATGCSFDGLNSLPLPGTVGT
MSMEG_2859|M.smegmatis_MC2_155 ---------MKP-RKPARGWLAVACCAVLTVSGCRFDGVNSLPLPGTVGT
MMAR_4706|M.marinum_M -------MTASTATPALRRLFVIGCCVMLAVTGCAFNGLNSLPLPGAVGR
TH_3627|M.thermoresistible__bu -----------------------------------------------XGT
MAB_4149c|M.abscessus_ATCC_199 ------------MSRNVLRAAVMGVGVAVVVSGCQFNGLNSLNLPGTAGH
MAV_2536|M.avium_104 --------MSQSPLRRRVMAALLAAVALATLSGCGFRGLNSFNLPGTKGG
MUL_3922|M.ulcerans_Agy99 --------MRAGWTTRIRIAAGIAALAVAVSGCSGWRGLNSLPLPGVQGG
Rv1970|M.tuberculosis_H37Rv --------MRIG-LTLVMIAAVVAS--------CGWRGLNSLPLPGTQGN
Mb0179|M.bovis_AF2122/97 ---MMSVLARMRVMRHRAWQGLVLLVLALLLSSCGWRGISNVAIPGGPGT
MLBr_02593|M.leprae_Br4923 MRRAMSVVHTSRVR-HQTWRGLVMLVAALLLSSCGWRGISNVSIPGGPGS
*
Mflv_4534|M.gilvum_PYR-GCK GSDAVTYRVQLANVGSLESNSPVMLDDVVVGAVG-----KMTFEDWHAAV
Mvan_2855|M.vanbaalenii_PYR-1 GSNALVYHLRIANVGTLESNSPVMLNDVVVGAVR-----KMTVNDFHADV
MSMEG_2859|M.smegmatis_MC2_155 GSDAATFHVQIANVGTLEPNSPVMIDDVVVGAVR-----RMTLAGWHADV
MMAR_4706|M.marinum_M GPGASVYHVEIANVGTLEANSPVMLNDVIVGSIS-----KMTVRGWHADV
TH_3627|M.thermoresistible__bu GPDAHVYHVELENVGTLESNSPVLLNDVVVGAVG-----RMRIDGWHARV
MAB_4149c|M.abscessus_ATCC_199 GSRSYTVTVELPDVTTLPQNSPVMVDDVTVGSVSGIDAFQKPDGSWYAGV
MAV_2536|M.avium_104 GPGAYTIRAQMPDVQNLQRNSRVRVNDVTVGNVI-----DIELQGWNALV
MUL_3922|M.ulcerans_Agy99 GPGSFTIQAQMPDVDNIEPNSRVRVGDVNVGTVT-----KIERQGWHALV
Rv1970|M.tuberculosis_H37Rv GPGSFAVQAQLPDVNNIQPNSRVRVADVTVGHVT-----KIERQGWHALV
Mb0179|M.bovis_AF2122/97 GPGSYTIYVQMPDTLAINGNSRVMVADVWVGSIR-----AIKLKNWVATL
MLBr_02593|M.leprae_Br4923 GKGAYTIYVQVPDTLAINGNSKVMVADVTVGSIR-----AINLKNWVATL
* : . .: :. : ** * : ** ** : .: * :
Mflv_4534|M.gilvum_PYR-GCK DISVRPDVVVPANAVATVGQTSLLGSMHVALDPPVGETPTGRLAPGANLP
Mvan_2855|M.vanbaalenii_PYR-1 DVSVKPDVVVPANAVATVGQTSLLGSMHVALDPPVGESPTGRLQPGASVP
MSMEG_2859|M.smegmatis_MC2_155 EVSVQPDVVVPANAVATVGQTSLLGSMHLALDPPVDSAPEGRLAPGATIP
MMAR_4706|M.marinum_M EISVRRGAVIPDNAVASVGQTSLLGSMHLALNSPLGQVSDQRLQPGSTIP
TH_3627|M.thermoresistible__bu DVSVRPDVVVPANAVATVGQTSLLGSMHLALDPPAGARPEGVLPPGSTIR
MAB_4149c|M.abscessus_ATCC_199 KVSLEPEVHLPANAVAKVAQTSLLGSQHIELAAPVGEPAVGKLTGGATIP
MAV_2536|M.avium_104 TMTIDGDVDLPANATATLGQTSLLGSVHVELAPPAGVAPQGKLKNGSLIP
MUL_3922|M.ulcerans_Agy99 TMKLNGNVELPANATATLGQTSLLGSLHIELAPPTDVPPEGNLREGSLIP
Rv1970|M.tuberculosis_H37Rv TMRLDGDVDLPANATAKIGTTSLLGSYHIELAPPKGEARQGKLRDGSLIA
Mb0179|M.bovis_AF2122/97 TLSLKKDVTLPKNATAKIGQTSLLGSQHVELAAPPD-PSPVPLKDGDTIP
MLBr_02593|M.leprae_Br4923 TLGLNKDVQLPKNTTAKIGQTSLLGSQHVELAAPAN-PSLELLKNGDTIP
: : . :* *:.*.:. ****** *: * .* . * * :
Mflv_4534|M.gilvum_PYR-GCK LNRTSTYPSTEQTLSSLSVVVNGGGLTQIGDIISNFSAALDGRQGQIRSL
Mvan_2855|M.vanbaalenii_PYR-1 IDRTSTYPSTEQTLSSLSVVVNGGGLTQIGDIIGNFNAALDGRQIQIRDL
MSMEG_2859|M.smegmatis_MC2_155 LSRSTTYPSTEQTLSSLSLVVNGGGLMQIADIVHNFSAALDGRAVEIRDL
MMAR_4706|M.marinum_M LSRSSTYPSTEQTLSSLSVILNAGGLGQIGDIIHNFTAALSGRTSDIRDL
TH_3627|M.thermoresistible__bu LDASSTYPSTEQTLASLSALINGGGLGQIGEVLGNAEAALRGRGDQVRDV
MAB_4149c|M.abscessus_ATCC_199 LSRTGKYPSTEEVLSALSVVVNKGNLGALQDITDETYNLFKGRTGNLTQV
MAV_2536|M.avium_104 LSSAGAYPSTERTLAAVSLLLNGGGLGQVQDITKTLSTAFSGREQDLRNL
MUL_3922|M.ulcerans_Agy99 LSSSKAYPSTEQALAATAMLLNGGGIGDIYDITEALSTAFTGRENDLRSL
Rv1970|M.tuberculosis_H37Rv LSHGSAYPSTEQTLAALSLVLNGGGLGQVQDITEALSTAFAGREHDLRGL
Mb0179|M.bovis_AF2122/97 LKRSSAYPTTEQTLASIATLLRGGGLVNLEGIQQEINAIVTGRADQIRAF
MLBr_02593|M.leprae_Br4923 LKNSSVFPTTEQTLASLSLILRGGGIPNLETLTNEVFNIFHGRADQIHAF
:. :*:**..*:: : ::. *.: : : . ** :: .
Mflv_4534|M.gilvum_PYR-GCK LTRMNDVVGILDDQRDNINATISALYRLSETFAGQREVLSAALKRIPEAL
Mvan_2855|M.vanbaalenii_PYR-1 LTRMNDVVGILDNQRANIIDTIGALNRLAETFANQREVLTAALSRIPQAL
MSMEG_2859|M.smegmatis_MC2_155 LTRMNNVVGILDNQRDNIVATIAAMNRVAGTFAAQRSTLTEALDRIPPAL
MMAR_4706|M.marinum_M LVRLDRFVGTFDEQRDNLVASIQALNRLAGTLAGQRDVITQALQKIPPAL
TH_3627|M.thermoresistible__bu LTRLNDIAGVLESQQADVVESLEQLGRLSGDLAAQQDSLTRALQAVPPAL
MAB_4149c|M.abscessus_ATCC_199 LPKLATLISSLNSQRDDIISAIEGIDKFSRVLAEHKESLGRAIDSIEPAL
MAV_2536|M.avium_104 LNQLDTFVGYLNDQKSDIIAATDHLNNLVGQFADQKPIIDKALKTIPQAL
MUL_3922|M.ulcerans_Agy99 IEQLDEAIGHLDDQKGDIIAAAESLNNLMAQLAAQRPVLDKALRTIPDAL
Rv1970|M.tuberculosis_H37Rv IGQLDTFTAYLNNQSGDIIAATDSLNRLVGKFADQQPVFDRALATIPDAL
Mb0179|M.bovis_AF2122/97 LGKLDTFTDELNQQRDDITRAIDSTNRLLAYVGGRSEVLNRVLTDLPPLI
MLBr_02593|M.leprae_Br4923 LTKLDTFASQLNQQRDDITHAIDSTNRLLTYVGGRSDVLDQILTDIPPLI
: :: ::.* :: : .. .. : : : : :
Mflv_4534|M.gilvum_PYR-GCK AVLNQQRPRIVTAMRKLGDFSDTATQLIDESQEDIVGNLRNLEPAVRALA
Mvan_2855|M.vanbaalenii_PYR-1 EVLNRQRPRIVTAMQKLGDFSDTATQLINESQEDIVRNLQNLEPAVRALA
MSMEG_2859|M.smegmatis_MC2_155 EVLASQRPQITTAMNKLGAFSDIAHRLINDSQADLVRNLKNLEPTVKALA
MMAR_4706|M.marinum_M DVLIRERPRITAALDKLGTFSDTATRLVNDAGSDLVQNLQNLGPTISALA
TH_3627|M.thermoresistible__bu EVLIRQRPRITTALQKLGELSRTATGLIHDTHTELVTNLQNLEPVLRALA
MAB_4149c|M.abscessus_ATCC_199 KVLNENRANIIEAFRSVGNLAKITDRVLRTTKDDIVADLKGLYPVVRALA
MAV_2536|M.avium_104 TVLKDERENLANALGEVGQLSALAADSVNKTKENLIKELKDLGPVLQSLA
MUL_3922|M.ulcerans_Agy99 TVLKNERENLADALTQLGRFSALAADSVNQTKDALVQELKDLGPTLESLA
Rv1970|M.tuberculosis_H37Rv AVLADERDTLVEAAEQLSKFSALTVDSVNKTTANLVTELRQLGPVLESLA
Mb0179|M.bovis_AF2122/97 KHFADKQELLINASDAVGRLSQSADQYLSAARGDLHQDLQALQCPLKELR
MLBr_02593|M.leprae_Br4923 KHFADTKNLLINAVGSVGQLSQAVDQYLSEARGPLHTDLQALACPLRELG
: : : * :. :: . : : : :*: * : *
Mflv_4534|M.gilvum_PYR-GCK DVGPDLATALSYLPTYPYTQEFIDRGIRGDYMNQFIVFDFTIPRLKSGIL
Mvan_2855|M.vanbaalenii_PYR-1 DVGPDLATALSYLPTYPYTQEFIDRGIRGDYMNQFIVFDFTISRLKSGIF
MSMEG_2859|M.smegmatis_MC2_155 DVGTDLVTALSYLPTYPYTQDFIDRGIRGDFMNQFIVFDFTIPRLKSGIL
MMAR_4706|M.marinum_M DIGPDLDAAIAYAPTFPFTQGFIDRYIRGDYVNGYFIIDLTNAGLRKSIL
TH_3627|M.thermoresistible__bu DVGPELDRVLAYLPTYPLSQDIIDRGVRGDYMNLFAVIDLTVPRLKRSAL
MAB_4149c|M.abscessus_ATCC_199 ENRDVLIDSLDLLPTFPFSTKYLRNAVRGDYLNVFVTFDLTARRLGETLF
MAV_2536|M.avium_104 DAGPALTRSLGFLGTFPFPAETLSKWIRGDYANLTAVIDLTLSRLDASFL
MUL_3922|M.ulcerans_Agy99 NAGPALTRALSFLPTYPFPKETLTNWMRGDYANLTLIIDMTLSRIDAGFF
Rv1970|M.tuberculosis_H37Rv NSGPALTRSLSLLATFPFPNETFQNFQRGEYANLTAIVDLTLSRIDQGLL
Mb0179|M.bovis_AF2122/97 RAAPYLVGALKLILTQPFDVDTVPQLVRGDYMNLSLTLDLTYSAIDNAFL
MLBr_02593|M.leprae_Br4923 RGAPYFIGAMKLILTQPYDVDTVPKIMRGDYQNVSLTLDVTYSAMDNAVL
: : * * . . **:: * .*.* : :
Mflv_4534|M.gilvum_PYR-GCK LGTRWGEPGASMVPAPGDPWYSMYTRDPLQAP-----ITPIPAEVAT---
Mvan_2855|M.vanbaalenii_PYR-1 LGTRWGEPGASMVPAPGDPWYSSYTLDPLQAP-----VTPVPDEVAT---
MSMEG_2859|M.smegmatis_MC2_155 LGTRWGQPGASLVPAPGDPWYSSYTLDPLKAP-----VTPKPTELAP---
MMAR_4706|M.marinum_M LGTHWGRLGAEGVPAPGDPEYLQFKFGAPIPPGPPPADAPPPGDPAP---
TH_3627|M.thermoresistible__bu LGTRFGQPRTPLIPAPGDPWHLAYTYDPLGVP-----VVPVPDPMADPTG
MAB_4149c|M.abscessus_ATCC_199 TTSFFDPNMQHFNDVVNPPEWLIGSMANLNGK-----ETSPFDLPAP---
MAV_2536|M.avium_104 TGTRFECNLTELELQWG------RTIGQLPSP----CTGGGPYNPGN---
MUL_3922|M.ulcerans_Agy99 TGTRWEGDLTELELQWG------RTIGQMPS----------PYTVGN---
Rv1970|M.tuberculosis_H37Rv TGTRWECHLTQLELQWG------RTIGQFPSP----CTAGYRGTPGN---
Mb0179|M.bovis_AF2122/97 TGTGFSGALRALEQSFGRDPETMIPDIRYTPN--------PNDAPGG---
MLBr_02593|M.leprae_Br4923 TGTGLSGALRALEQSFGRDPETMIPDVRYTTN--------PNDAPGG---
: . .
Mflv_4534|M.gilvum_PYR-GCK ---------------------------------IPPLVDLPPAPAGEPAG
Mvan_2855|M.vanbaalenii_PYR-1 ---------------------------------MPPLIEAPASATGQPVE
MSMEG_2859|M.smegmatis_MC2_155 ---------------------------------FPPTVDG--AGDAAPAA
MMAR_4706|M.marinum_M ---------------------------------GPPPDSAVPIPGATPAE
TH_3627|M.thermoresistible__bu SDDEPAAQPAVPDEAVAATDTGIPAYDGAILPVQPPIFSMSAAGPSAPLF
MAB_4149c|M.abscessus_ATCC_199 ---------------------------------------------AAPQG
MAV_2536|M.avium_104 -----------------------------------------PLVVPYHFD
MUL_3922|M.ulcerans_Agy99 -----------------------------------------PLIVPYRWD
Rv1970|M.tuberculosis_H37Rv -----------------------------------------PLTIAYRWD
Mb0179|M.bovis_AF2122/97 -------------------------------------------PLVERGN
MLBr_02593|M.leprae_Br4923 -------------------------------------------PLVERAD
Mflv_4534|M.gilvum_PYR-GCK GGS--------
Mvan_2855|M.vanbaalenii_PYR-1 AGGN-------
MSMEG_2859|M.smegmatis_MC2_155 EGGN-------
MMAR_4706|M.marinum_M AAPTDGGP---
TH_3627|M.thermoresistible__bu AGPYPHDRGGG
MAB_4149c|M.abscessus_ATCC_199 GGR--------
MAV_2536|M.avium_104 QGR--------
MUL_3922|M.ulcerans_Agy99 QGP--------
Rv1970|M.tuberculosis_H37Rv QGP--------
Mb0179|M.bovis_AF2122/97 RQC--------
MLBr_02593|M.leprae_Br4923 RRC--------