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VADEVLLERRDRVLIITINRPEARNAFNLAVAQGLADAMDELDSSAELSVAIITGAGGNFCAGMDLKAFM AGEVPAIEGRGIGFTERPPRKPVIAAVEGYALAGGTEIVLATDLIVAAKNAKFGIPEVKRGLVAAGGGLL RLQKRIPYQKALELALTGDSFTAEEASQWGFVNVLTEPGEALNGALALAERITANGPLAVAVTKEVIVKS ADWTEAEMWKKQGELVMSVFSSKDAMEGATAFAEKRKPNWTGS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1990 | - | - | 100% (253) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_4588 | - | 2e-56 | 46.30% (257) | enoyl-CoA hydratase/isomerase |
| M. vanbaalenii PYR-1 | Mvan_5216 | - | 3e-50 | 44.53% (256) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3545 | echA19 | 7e-50 | 44.36% (257) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_4354 | - | 1e-133 | 94.47% (253) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv0222 | echA1 | 7e-95 | 67.60% (250) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 4e-36 | 36.26% (262) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_4588c | - | 2e-97 | 69.84% (252) | enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_0465 | echA1 | 3e-93 | 67.20% (250) | enoyl-CoA hydratase EchA1 |
| M. avium 104 | MAV_4951 | - | 3e-95 | 69.20% (250) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_2227 | - | 1e-120 | 84.65% (254) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_3963 | - | 2e-95 | 69.08% (249) | PUTATIVE enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_1114 | echA1 | 5e-93 | 66.80% (250) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1990|M.vanbaalenii_PYR-1 ----------MADEVLL-ERRDRVLIITINRPEARNAFNLAVAQGLADAM
Mflv_4354|M.gilvum_PYR-GCK ----------MSDEVLL-ERRDRVLIITINRPEARNAFNLAVAQGLADAM
MSMEG_2227|M.smegmatis_MC2_155 ----------MSEEVVLRERRDRTLIITINRPEARNAFNLAVAKGLAEAV
MMAR_0465|M.marinum_M MSELN----GDTEPEVLVEQRDRILIITINRPKAKNSVNAAVSRALADAM
MUL_1114|M.ulcerans_Agy99 MSELN----GDTEPEVLVEQRDRILIITINRPKAKNSVNAAVSRALADAM
Rv0222|M.tuberculosis_H37Rv MSSESDA--ANTEPEVLVEQRDRILIITINRPKAKNAVNAAVSRGLADAM
MAV_4951|M.avium_104 MRHVSTGNEEAGEPEVLVEQRDRILIITINRPKAKNAVNAAVANGLAAAV
TH_3963|M.thermoresistible__bu VTEQG-----SSDNPVLVEQRGRILIITINRPEAKNAVNLAVAQGLAAAM
MAB_4588c|M.abscessus_ATCC_199 -----------MADEVLIEQRDRVLLITINRPDARNAVNRAVSQGLAAAA
Mb3545|M.bovis_AF2122/97 ---------MESGPDALVERRGHTLIVTMNRPAARNALSTEMMRIMVQAW
MLBr_02402|M.leprae_Br4923 ----------MKYDTILVDGYQRVGIITLNRPQALNALNSQMMNEITNAA
* : : ::*:*** * *:.. : . :. *
Mvan_1990|M.vanbaalenii_PYR-1 DELDSSAELSVAIITGAGGNFCAGMDLKAFMA---GEVPAIEGRGIG---
Mflv_4354|M.gilvum_PYR-GCK DELDDTPELSVAIITGAGGNFCAGMDLKAFMA---GEVPAIEGRGIG---
MSMEG_2227|M.smegmatis_MC2_155 DELDDTQELSVGIITGAGGTFCAGMDLKGFAS---GELPHVPGRGIG---
MMAR_0465|M.marinum_M DRLDADAGLSVGILTGAGGSFCAGMDLKAFAR---GENVVVEGRGLG---
MUL_1114|M.ulcerans_Agy99 DRLDADAGLSVGILTGAGGSFCAGMDLKAFAR---GENVVVEGRGLG---
Rv0222|M.tuberculosis_H37Rv DQLDGDAGLSVAILTGGGGSFCAGMDLKAFAR---GENVVVEGRGLG---
MAV_4951|M.avium_104 DRLDSEPGLSVGVLTGAGGSFCAGMDLKAFAR---GELPIVEGRGMG---
TH_3963|M.thermoresistible__bu DRLDDDKGLSVGIVTGAGGSFSAGMDLKAFAR---GEFPVVEGRGLG---
MAB_4588c|M.abscessus_ATCC_199 DQLDSSADLSVAIITGAGGNFCAGMDLKAFVS---GEAVLSE-RGLG---
Mb3545|M.bovis_AF2122/97 DRVDNDPDIRCCILTGAGGYFCAGMDLKAATQKPPGDSFKDGSYDPSRID
MLBr_02402|M.leprae_Br4923 KELDIDPDVGAILITGSPKVFAAGADIKEMASLTFTDAFDADFFSAWG--
..:* : ::**. *.** *:* : .
Mvan_1990|M.vanbaalenii_PYR-1 --FTERPPRKPVIAAVEGYALAGGTEIVLATDLIVAAKNAKFGIPEVKRG
Mflv_4354|M.gilvum_PYR-GCK --FTERPPRKPLIAAVEGYALAGGTEIVLATDLIVAAKNAKFGIPEVKRG
MSMEG_2227|M.smegmatis_MC2_155 --FTEKPPRKPLIAAVEGYALAGGTEIVLATDLVVASRTAKFGIPEVKRG
MMAR_0465|M.marinum_M --FTERPPAKPLIAAVEGYALAGGTELALATDLIVAARDSAFGIPEVKRG
MUL_1114|M.ulcerans_Agy99 --FTERPPAKPLIAAVEGYALAGGTELALATDLIVAARDSAFGIPEVKRG
Rv0222|M.tuberculosis_H37Rv --FTERPPTKPLIAAVEGYALAGGTELALAADLIVAARDSAFGIPEVKRG
MAV_4951|M.avium_104 --FTERPPAKPLIAAVEGYALAGGTELALATDLIVASKDAAFGIPEVKRG
TH_3963|M.thermoresistible__bu --YTEKPPAKPLIAAVEGYALAGGTELALAADMIVASRESAFGIPEVKRG
MAB_4588c|M.abscessus_ATCC_199 --FTNVPPRKPIIAAVEGFALAGGTELVLSCDLVVAGRSAKFGIPEVKRG
Mb3545|M.bovis_AF2122/97 ALLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWS
MLBr_02402|M.leprae_Br4923 ---KLAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLG
. .*:**** * *:.** *: *: :*. : ** .* * .
Mvan_1990|M.vanbaalenii_PYR-1 LVAAGGGLLRLQKRIPYQKALELALTGDSFTAEEASQWGFVNVLTEPGEA
Mflv_4354|M.gilvum_PYR-GCK LVAAGGGLLRLQKRIPYQKALELALTGDSFTAEEASAWGFVNVLTEPGGA
MSMEG_2227|M.smegmatis_MC2_155 LVAAGGGLLRLPKRIPYQKALELALTGDNFTAEEAAAWGFVNKLTEPGEA
MMAR_0465|M.marinum_M LVAGGGGLLRLPERIPYAIAMELALTGDNLSAERAHALGMVNVLAEPGAA
MUL_1114|M.ulcerans_Agy99 LAAGGGGLLRLPERIPYAIAMELALTGDNLSAERAHALGMVNVLAEPGAA
Rv0222|M.tuberculosis_H37Rv LVAGGGGLLRLPERIPYAIAMELALTGDNLPAERAHELGLVNVLAEPGTA
MAV_4951|M.avium_104 LVAGGGGLLRLPQRIPSAIAMELALTGDNLSAERAHALGMVNVLAEPGSA
TH_3963|M.thermoresistible__bu LVAGGGGLLRLPERIPYSIAMELALTGDILPAERAHDLGLVNALTEPGAA
MAB_4588c|M.abscessus_ATCC_199 LVAGAGGLLRLPNRIPYQVAMELALTGESFTAEDAAKYGFINRLVDDGQA
Mb3545|M.bovis_AF2122/97 LYPMGGSAVRLVRQIPYTLACDLLLTGRHITAAEAKEMGLIGHVVPDGQA
MLBr_02402|M.leprae_Br4923 VLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDL
: . *. ** . * * :* *** : * * *::. :. .
Mvan_1990|M.vanbaalenii_PYR-1 LNGALALAERITANGPLAVAVTKEVIVKSADWTEAEMWKKQGELVMSVFS
Mflv_4354|M.gilvum_PYR-GCK LDGALALAERITANGPLAVAATKEVIAKSADWTEAEMWKKQGEIVFPVFS
MSMEG_2227|M.smegmatis_MC2_155 LAGALELAERITANGPLAVAVTKEVIVKSAEWSEAEMWKKQGELIGPVFS
MMAR_0465|M.marinum_M LDAAIALAEKITANGPLAVAATKRIITESRGWSLDTRFAQQMKILFPIFT
MUL_1114|M.ulcerans_Agy99 LDAAIALAEKITANGPLAVAATKRIITESRGWSLDTRFAQQMKILFPIFT
Rv0222|M.tuberculosis_H37Rv LDAAIALAEKITANGPLAVVATKRIITESRGWSPDTMFAEQMKILVPVFT
MAV_4951|M.avium_104 LDEAIALAEKIAANGPLAVAATKRIIVESRGWSPETMFAEQNKLLAPVFS
TH_3963|M.thermoresistible__bu LDGAIELAERIAANGPLAVATTKRIIIESKKWTPDTMFAEQGKLMAPVFS
MAB_4588c|M.abscessus_ATCC_199 LDTALELAAKITANGPLAVAATKRIIIESASWAPEEAFAKQGEILMPIFV
Mb3545|M.bovis_AF2122/97 LTKALELADAISANGPLAVQAILRSIRETECMPENEAFKIDTQIGIKVFL
MLBr_02402|M.leprae_Br4923 LPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHSTFV
* * :* *: . *. . : .: . : .: *
Mvan_1990|M.vanbaalenii_PYR-1 SKDAMEGATAFAEKRKPNWTGS
Mflv_4354|M.gilvum_PYR-GCK SKDAMEGATAFAEKRKPNWTGT
MSMEG_2227|M.smegmatis_MC2_155 SKDAIEGATAFAEKRKPNWTGS
MMAR_0465|M.marinum_M SNDAKEGAIAFAEKRPPRWTGT
MUL_1114|M.ulcerans_Agy99 SNDAKEGAIAFAEKRPPRWTGT
Rv0222|M.tuberculosis_H37Rv SNDAKEGAIAFAERRRPRWTGT
MAV_4951|M.avium_104 SNDAKEGAIAFAEKRPPKWTGT
TH_3963|M.thermoresistible__bu SNDAKEGAIAFAEKRAPNWTGT
MAB_4588c|M.abscessus_ATCC_199 SEDAKEGAKAFAEKRAPVWQGK
Mb3545|M.bovis_AF2122/97 SDDAKEGPRAFAEKRAPNFQNR
MLBr_02402|M.leprae_Br4923 TDDQSEGMAAFIEKRAPQFTHR
:.* ** ** *:* * :