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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4437 | - | - | 100% (396) | virulence factor |
| M. thermoresistible (build 8) | TH_2722 | - | e-128 | 57.97% (395) | PUTATIVE virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_2680 | - | e-116 | 54.16% (397) | PUTATIVE virulence factor Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3529c | mce4A | 1e-56 | 35.60% (368) | MCE-family protein MCE4A |
| M. gilvum PYR-GCK | Mflv_2508 | - | 1e-135 | 61.90% (399) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv1966 | mce3A | 4e-62 | 38.35% (412) | MCE-family protein MCE3A |
| M. leprae Br4923 | MLBr_02589 | mce1A | 3e-52 | 34.67% (375) | putative cell invasion protein |
| M. abscessus ATCC 19977 | MAB_4153c | - | 1e-64 | 39.44% (355) | MCE-family protein |
| M. marinum M | MMAR_4710 | - | 1e-141 | 63.27% (392) | MCE-family protein |
| M. avium 104 | MAV_0948 | - | 1e-145 | 62.85% (393) | virulence factor Mce family protein, putative |
| M. smegmatis MC2 155 | MSMEG_4794 | - | 1e-170 | 74.37% (394) | virulence factor |
| M. ulcerans Agy99 | MUL_3918 | mce3A_1 | 8e-65 | 40.96% (354) | MCE-family protein Mce3A_1 |
| M. vanbaalenii PYR-1 | Mvan_2851 | - | 1e-134 | 59.69% (392) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1966|M.tuberculosis_H37Rv -------------------------MRRGPGRHRLHDAWWTLILFAVIGV
MUL_3918|M.ulcerans_Agy99 ---------------------------MDDRKEGLHPAWHTLILVLLFVA
Mb3529c|M.bovis_AF2122/97 --------------------------MSGGGSRRTSVRVAAALLAGLMVG
MAB_4153c|M.abscessus_ATCC_199 --------------------------MSDTSTRR-AVRLAGTVLASVLVL
TH_4437|M.thermoresistible__bu ------------------------------MSRSYARPLAGLATVVVIGL
MSMEG_4794|M.smegmatis_MC2_155 MTRNVGPGPAHRSETDSSAAPVAARPGRSFGARGHARPLAGLATVVVVGL
Mflv_2508|M.gilvum_PYR-GCK ------------------------------MNKNLVRPLAGLGMVVALLV
MMAR_4710|M.marinum_M MSRNLGPNPMHRSETASAAAPVAASPGRHFGVSSYARPLAGLATVLVIAL
MAV_0948|M.avium_104 MTQNVPAG-----RGAIAGRPPRPGHAHPPAGRNYLPPLLGLATILIIGL
Mvan_2851|M.vanbaalenii_PYR-1 --------------MAIDS--------------SVRRPLIGLATVLAVAA
MLBr_02589|M.leprae_Br4923 ----------------------MTSSTKINASRKPPYKLAGVGLLVVAVV
Rv1966|M.tuberculosis_H37Rv AVLVTAVSFTGSLRSTVPVTLAADRSGLVMDSGAKVMMRGVQVGRVAQIG
MUL_3918|M.ulcerans_Agy99 AMWVTYALFMGSLRSVVPVTLTSERSGLVMETNAKVKLRGVQVGRVASIV
Mb3529c|M.bovis_AF2122/97 SAVLTYLSYTAAFTSTDTVTVSSPRAGLVMEKGAKVKYRGIQVGKVTDIS
MAB_4153c|M.abscessus_ATCC_199 LTVLTYLAYNDAFADTKPITVVSPRAGLVMEEGGKVKFHGLQIGKVTSIS
TH_4437|M.thermoresistible__bu IIAVAIGLFQGSFRKSVPVTVIAERAGLVMNPDAKVKMRGVQVGQVDRIE
MSMEG_4794|M.smegmatis_MC2_155 IIALAVTLFRGDFTKTEPVTLISDRVGLVMNPDAKVKMRGVQVGTVGRIE
Mflv_2508|M.gilvum_PYR-GCK ILAVSIGLFAGKFTETVPVTVISDRAGLVMNPDAKVKMRGVQVGTVKSID
MMAR_4710|M.marinum_M IVAVAVGLFRGDFTQSVPVTVVSPRAGLVMNPDAKVKMRGVEVGKVAAID
MAV_0948|M.avium_104 IFAVAVGLFQGSFTETVPVTVISQRAGLVMNPDAKVKMRGVQVGKVASIE
Mvan_2851|M.vanbaalenii_PYR-1 VIAVAVGLFRGSFTKTVPVTVLSQRAGLVMNADAKVKLHGAQVGSVHSIE
MLBr_02589|M.leprae_Br4923 IFGLVYGQFRGNFTPKSKLTMLADRAGLVMDRGSKITYNGVKIGRVADIS
: : : :*: : * ****: ..*: .* ::* * *
Rv1966|M.tuberculosis_H37Rv RIE-WAQNGASLRLEIDPDQIRYIPANVEAQISATTAFGAKFVDLVMPQN
MUL_3918|M.ulcerans_Agy99 GGG-KGATPVALTLEIDSDQIRYIPANVQAEIRATTVFGAKFVDLIYPED
Mb3529c|M.bovis_AF2122/97 Y---SGN-QARLKLAIDSGEMGFIPSNATVRIAGNTIFGAKSVEFIPPKT
MAB_4153c|M.abscessus_ATCC_199 Y---AND-QAKLELAVNAKDLRLIPSNATVRIAGTTVFGAKSVEFLAPQK
TH_4437|M.thermoresistible__bu N---RPDGTAVLHLAMDPSQLHLIPKNVIADIASTTVFGAKSVQLTMPPE
MSMEG_4794|M.smegmatis_MC2_155 T---LPDGRAALHLDMDPGQLRLIPGNVTADIASSTVFGAKFVDLVPPGK
Mflv_2508|M.gilvum_PYR-GCK Y---RPDGTAALQLDMDPSQLPLIPENVNVDIASSTVFGAKFVQFEAPEN
MMAR_4710|M.marinum_M V---RSNGDAVLHLAMDPSQIRLIPSNVLVDIASTSVFGAKFVELVPPEQ
MAV_0948|M.avium_104 S---LPNGQAAIHLAMDPSQMHFIPSNVLVDIASSTVFGAKSIQLVEPAQ
Mvan_2851|M.vanbaalenii_PYR-1 A---LPDGRAAIHLAMDPSYMDIIPSDVRVDIASSTVFGSKFVELVPPAD
MLBr_02589|M.leprae_Br4923 ETVRNGRPVAEFTLDVYPRYLSLIPANVNADIKATTVFGGKYVSLTTPEH
. : * : . : ** :. . * ..: **.* :.: *
Rv1966|M.tuberculosis_H37Rv PSRARLSAGAVLHSKNVSTEINTVFENVVDLLNMIDPLKLNAVLTAVADA
MUL_3918|M.ulcerans_Agy99 PSPQRLKAGQVLMSRNVTSEANTVFQNLVAVLDQIDPAKLNAALSALAEG
Mb3529c|M.bovis_AF2122/97 PSPKPLSPNAHVAASQVQLEVNTLFQSLIDLLHKIDPLETNATLSALSEG
MAB_4153c|M.abscessus_ATCC_199 PSDSSLRPGATVTAEAVALEVNTVFENLTRLLGKIDPVNLNATLTAVGEG
TH_4437|M.thermoresistible__bu PSAERLQPGQVLRGDHVMIEINTIFQQLVDVLDHIDPVKLNETLGAIASA
MSMEG_4794|M.smegmatis_MC2_155 P-EGTLQPGQVLQGEHVTVEVNTVFQQLTRVLDKIDPAKLNETLGAISAA
Mflv_2508|M.gilvum_PYR-GCK P-VGELRTGQVLRGDHVTVEINTVFQQLVNVLDAVDPLKLNETLGALSQA
MMAR_4710|M.marinum_M PSSESLQPHQVLEGKHVTVEVNTVFQQLTSLLSAIDPAKLNETLGAIASA
MAV_0948|M.avium_104 PSAQRLRAGQTLQGQHVMVEINTVFQELVSVLSHIDPPKLNESLGALAQA
Mvan_2851|M.vanbaalenii_PYR-1 PSAQPLQPGQVLDAEHVTVEINTVFEQLSSVLAKIEPAKLNQTLGALATA
MLBr_02589|M.leprae_Br4923 PSQKRLTPQTVIDARSVTTEINTLFQTITLIAEKVDPIKLNLTLSAAAQS
* * . : . * * **:*: : : ::* : * * * . .
Rv1966|M.tuberculosis_H37Rv VRGQGERIGQATTDLNEVLEALNARGDTIGGNWRSLKNFTDTYDAAAQDI
MUL_3918|M.ulcerans_Agy99 LRGQGPLIGQATTDANQVLLELNPRYETVTADLRAVKDFNDTFSAAAQDI
Mb3529c|M.bovis_AF2122/97 LRGHGDDLGALLSGLNTLTRQANPKLPALQEDFRKAAVVANVYADAAGDL
MAB_4153c|M.abscessus_ATCC_199 LRGNGDNFGQGLVELDQYLDQLNPKLPALQQDFRQAGQVGQIYGDAAPDI
TH_4437|M.thermoresistible__bu FSGRGEQFGQTLTDFEALLARLEPSLPAFSRDLELSAQVSAAYADAAPNL
MSMEG_4794|M.smegmatis_MC2_155 FGGRGEKMGQTVSDFEALLEKLEPSLPNLNRDIESMAVVSGAYGDAAPDL
Mflv_2508|M.gilvum_PYR-GCK FSGRGEKFGQTLTDFNALLAELEPSLPNLSRDIEAAVPTLEAYGDAAPDL
MMAR_4710|M.marinum_M VNGRGHKIGQMLSDLDSFLAKQDPSLPALSHDLAVLPVVSNAYADAAQDL
MAV_0948|M.avium_104 FSGRGPQLGQSLSDLDSFLARLEPSLPAFRHDLSVLPTVSNAYADAAPDL
Mvan_2851|M.vanbaalenii_PYR-1 FDGRGDQLGQMMADVDGLLAEIEPSLPVMEHELAVAPQVIGTYADVAQEL
MLBr_02589|M.leprae_Br4923 LAGLGERFGQSIVNGNSVLDDVNSQLPQARHDIQQLASLGDTYANSASDF
. * * :* : :. : : * ::
Rv1966|M.tuberculosis_H37Rv LTILNAASTTSATVVNHSTQLDALLLNAIGLSNAGTNLLGSSRDNLVGAA
MUL_3918|M.ulcerans_Agy99 LDTLNALSTTSTTITGHSTQLDALLLATIGLSNTGISLLAPNQANLIKAI
Mb3529c|M.bovis_AF2122/97 NTVFDNLPTINKTIVDQKDNLNDTLLATIGLSNNAYETLAPAEQNFIDAI
MAB_4153c|M.abscessus_ATCC_199 VRILDNLPALSRTVVDQQQDLKATLLAAIGLGNNGYETLAPAEKDLTAAL
TH_4437|M.thermoresistible__bu LRTMQNSITLSDGIVDEQDNLDAFLVSAIGLADVGNDVLGGNREAFSEVL
MSMEG_4794|M.smegmatis_MC2_155 LKTIENTNRISDSIVDEQQNLDAFLVSSIGLADVGNDVIGGNREALSTTL
Mflv_2508|M.gilvum_PYR-GCK VSIFENTTTLGNSIVDEQENLDQFLISSIGLADLGNEVVGGNREALTNVL
MMAR_4710|M.marinum_M VNTAENAIRISKSIVDEQQNLDAFLISSIGLADVGNDVVGGNRQALTDVL
MAV_0948|M.avium_104 VKTAANATRISKTLVDEQHNLDALLISAIGLADIGNDVLSTNRQPLTNVL
Mvan_2851|M.vanbaalenii_PYR-1 VDTVEAVTTISQTVIDEQDNLDSLLVSVIGLSDNGIEVVGGNRQAITDVM
MLBr_02589|M.leprae_Br4923 FDFLNNSIVTSRTINQQQKDLDQVLLAAVGFGNTGADIFSRSGPYLARGA
. : .. :*. *: :*:.: . . .. :
Rv1966|M.tuberculosis_H37Rv DILAPTTSLLFKYNPEYTCFLQ----------------------------
MUL_3918|M.ulcerans_Agy99 NALEPTTNLLYKYSPEYTCLLE----------------------------
Mb3529c|M.bovis_AF2122/97 NRLRAPLKVTSDYSPVFGCLFK----------------------------
MAB_4153c|M.abscessus_ATCC_199 QRLRAPATLLGRYSPEIPCTLQ----------------------------
TH_4437|M.thermoresistible__bu ELLVPTTNLLNEYAPAINCSLL----------------------------
MSMEG_4794|M.smegmatis_MC2_155 DLLAPTTDLLNEYAPGLNCALE----------------------------
Mflv_2508|M.gilvum_PYR-GCK DVLVPTTQLLHDYRKSLWCGIG----------------------------
MMAR_4710|M.marinum_M DLLVPTSDLLYEYRQALWCGIS----------------------------
MAV_0948|M.avium_104 HLLVPTTDLTNEYAPALTCSFG----------------------------
Mvan_2851|M.vanbaalenii_PYR-1 ELLVPTTDLLNRYHTALNCGLG----------------------------
MLBr_02589|M.leprae_Br4923 ADLVPTAQLLDTYSPAIFCTLRNYHDIEPKVTSFLGGNGYSINDHVELLS
* .. : * * :
Rv1966|M.tuberculosis_H37Rv GAKWYLDNGGYAAWGGADGRTLQLDVALLFG------NDPYVYPDNLPVV
MUL_3918|M.ulcerans_Agy99 GAKYLLDHGGYEAPGG-NGRSLVLDAALALG------DDPYRFPDNLPII
Mb3529c|M.bovis_AF2122/97 GIARGVK--EFAPLIGVRKAGLFTSSSFVLG------APSYTYPESLPIV
MAB_4153c|M.abscessus_ATCC_199 AISKALV--TFTPLIGGVRPGLFLTNSFPLG------APVYTYPDSLPIV
TH_4437|M.thermoresistible__bu GMEYVMN--QPP----LMDPGVLVNVAFTLG------IDRYRYPSNLPKV
MSMEG_4794|M.smegmatis_MC2_155 GMAWVKN--QPP----QSDPGVLVNVAFTLG------IERYRYPQNLPKV
Mflv_2508|M.gilvum_PYR-GCK GLVPFAQ--SPP----QFS-GIFVSAGLTLG------VERYRYPRDLPKV
MMAR_4710|M.marinum_M GSLVNLH--APP----LPEPMIKVLVYLGFG------AERYRYPSNLPKV
MAV_0948|M.avium_104 GLITIAH--GPP----LSEPSINISASLTWG------GERYRYPTNLPKV
Mvan_2851|M.vanbaalenii_PYR-1 GAVQLAK--APG----TPVPGGLLLQTIVLG------QERYRYPQNLPKV
MLBr_02589|M.leprae_Br4923 GLGFLLNPTSAISIIGAGVLSQGLLAPLGLAGVVNGAANPYIYPENLPRV
. : . * :* .** :
Rv1966|M.tuberculosis_H37Rv AAKGGPGGRPGCG--PLPDATHNFPVRQLVTNTGWGTGLDIRPNPGIGHP
MUL_3918|M.ulcerans_Agy99 GAKGGPGGKPGCG--SLPIVDNNWPVRNLVTNTGFGTGMDWRPNPGIGFP
Mb3529c|M.bovis_AF2122/97 NASGG----PNCR--GLPDIPTKQTGGSFYRAPFLVTDNALIP-------
MAB_4153c|M.abscessus_ATCC_199 NASGG----PNCR--GLPNIPTKMQNGSWFRSPFLVTDNAYIP-------
TH_4437|M.thermoresistible__bu GAKGG----PHC--MGLPFIGFGN------RSKYLVTDVNANP-------
MSMEG_4794|M.smegmatis_MC2_155 AAKGG----PHC--MGLPHIGFGQ------RSKYLVTDTNANP-------
Mflv_2508|M.gilvum_PYR-GCK AAKSGG--RDYCAELGLPEMPAEF------VPPMIVGDVGANP-------
MMAR_4710|M.marinum_M AATGG----PQC--YDLPLVPFDK------APPFVVADVGANP-------
MAV_0948|M.avium_104 AATGG----PKC--MGLPTLPFNT------NPPQFITDIGANP-------
Mvan_2851|M.vanbaalenii_PYR-1 AAKGG----PQC--TDLPKVGFEK------HPPFVITDVNANP-------
MLBr_02589|M.leprae_Br4923 NARGGPGGAPGCWQHITRDLWPTP-------ELVMDTGNSIAP-------
* .* * . *
Rv1966|M.tuberculosis_H37Rv CWANYFPVTRAVPEPPSIRQCIPGPAIGPNPAAGEQP-------------
MUL_3918|M.ulcerans_Agy99 GWANYFPVTRGTPEPPSIRNLFGGPAPGPIPYPGAPPYGAELYAPDGTPL
Mb3529c|M.bovis_AF2122/97 ---YQPFTELQVDAPSTLQFLFNGAFAERDDF------------------
MAB_4153c|M.abscessus_ATCC_199 ---YKPLEELQVNAPDTLQYLYNGAFAKRSEF------------------
TH_4437|M.thermoresistible__bu ---WQYGNQGIVLNSDGLKQLLFGPLDGPPRNTAQIGQPG----------
MSMEG_4794|M.smegmatis_MC2_155 ---WQYGNQGILLNSDGLKQLLFGPLDGPPRNTAQIGMPG----------
Mflv_2508|M.gilvum_PYR-GCK ---AQYGNSGILLNSEGLKNWLFGPLDGPPRNTAQIGQPG----------
MMAR_4710|M.marinum_M ---MQYGNPQLLLNSDALKQLLYGPIDGPPRNTMQIGQPG----------
MAV_0948|M.avium_104 ---VGYGNPQLLINSDLLKQLLYGPIAGPPRNSAQVGMPG----------
Mvan_2851|M.vanbaalenii_PYR-1 ---AQYGNQGIVLNSDGLKQLLFGPIDGPPRNTPQIGQPG----------
MLBr_02589|M.leprae_Br4923 ------YNHLDSGSPYAIEYVWGRQVGDNTINP-----------------
. :.
Rv1966|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3918|M.ulcerans_Agy99 WPGLPPAPPPGAPRESGPTPGSEPFVVPASAQAQPTPLPPAPLPQEVAPS
Mb3529c|M.bovis_AF2122/97 --------------------------------------------------
MAB_4153c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4437|M.thermoresistible__bu --------------------------------------------------
MSMEG_4794|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2508|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4710|M.marinum_M --------------------------------------------------
MAV_0948|M.avium_104 --------------------------------------------------
Mvan_2851|M.vanbaalenii_PYR-1 --------------------------------------------------
MLBr_02589|M.leprae_Br4923 --------------------------------------------------
Rv1966|M.tuberculosis_H37Rv -
MUL_3918|M.ulcerans_Agy99 P
Mb3529c|M.bovis_AF2122/97 -
MAB_4153c|M.abscessus_ATCC_199 -
TH_4437|M.thermoresistible__bu -
MSMEG_4794|M.smegmatis_MC2_155 -
Mflv_2508|M.gilvum_PYR-GCK -
MMAR_4710|M.marinum_M -
MAV_0948|M.avium_104 -
Mvan_2851|M.vanbaalenii_PYR-1 -
MLBr_02589|M.leprae_Br4923 -