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M. thermoresistible (build 8) TH_4436 (-)

annotation: RNA polymerase, sigma-24 subunit, ECF subfamily
coordinates: 436443 - 437033
length: 197

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4436--100% (197)RNA polymerase, sigma-24 subunit, ECF subfamily
M. thermoresistible (build 8)TH_0665sigH3e-4450.56% (180) ALTERNATIVE RNA POLYMERASE SIGMA-E FACTOR (SIGMA-24) SIGH
M. thermoresistible (build 8)TH_0545sigE3e-1432.75% (171) ALTERNATIVE RNA POLYMERASE SIGMA FACTOR SIGE

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3250csigH1e-4449.47% (190) RNA polymerase sigma factor RpoE
M. gilvum PYR-GCKMflv_4689-3e-4651.06% (188) ECF subfamily RNA polymerase sigma-24 factor
M. tuberculosis H37RvRv3223csigH1e-4449.47% (190) RNA polymerase sigma factor RpoE
M. leprae Br4923MLBr_01076sigE5e-1432.21% (149) RNA polymerase sigma factor SigE
M. abscessus ATCC 19977MAB_3543c-1e-4246.56% (189) RNA polymerase sigma-E factor
M. marinum MMMAR_1334sigH1e-4550.27% (185) alternative RNA polymerase sigma-E factor (sigma- 24) SigH
M. avium 104MAV_4171-2e-4550.00% (188) RNA polymerase sigma factor RpoE
M. smegmatis MC2 155MSMEG_1690-1e-4953.30% (182) putative ECF sigma factor RpoE1
M. ulcerans Agy99MUL_2545sigH8e-4549.73% (185) RNA polymerase sigma factor RpoE
M. vanbaalenii PYR-1Mvan_5003-5e-4652.63% (190) ECF subfamily RNA polymerase sigma-24 factor

CLUSTAL 2.0.9 multiple sequence alignment


Mb3250c|M.bovis_AF2122/97           ----------------------------------------MAD----IDG
Rv3223c|M.tuberculosis_H37Rv        ----------------------------------------MAD----IDG
MMAR_1334|M.marinum_M               -MSTSTSLLGEERLGRFPASPASVATLSGGTSTEGTVFIKMAD----IDG
MUL_2545|M.ulcerans_Agy99           ----------------------------------------MAD----IDG
MAV_4171|M.avium_104                MVSTATSLLGEEQLAGFLASPGALSVLSGDTAAEGTGFIEMADSPDGPDG
Mflv_4689|M.gilvum_PYR-GCK          -------MVPVMAMKAPSRSVFVLDVIGG-AATEGTVFPTMTD----TNG
MAB_3543c|M.abscessus_ATCC_199      --------------MACLERPMSVPIRMVGVATERTAVTSMDS-------
TH_4436|M.thermoresistible__bu      --------------------------------------------------
MSMEG_1690|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_5003|M.vanbaalenii_PYR-1       -------------------------------------------------M
MLBr_01076|M.leprae_Br4923          -MGDGIGMEREGRWTGNTQCPLRVVPGDESPTLDGRASPEDLIITNLLSP
                                                                                      

Mb3250c|M.bovis_AF2122/97           VTGSAGLQP--------GPSEETDEELTARFERDAIPLLDQLYGG-----
Rv3223c|M.tuberculosis_H37Rv        VTGSAGLQP--------GPSEETDEELTARFERDAIPLLDQLYGG-----
MMAR_1334|M.marinum_M               VTLAEAPDP--------EPPEETDEQLTARFERDAIPLLDQLYGG-----
MUL_2545|M.ulcerans_Agy99           VTLAEAPDP--------EPPEETDEQLTACFERDAIPLLDQLYGG-----
MAV_4171|M.avium_104                VTSPEVPEAHAEPAAHEETREETDAELTARFERDAIPLLDQLYGG-----
Mflv_4689|M.gilvum_PYR-GCK          LAASPAPADAG------EAREETDAELTARFERDAIPLLDQLYGG-----
MAB_3543c|M.abscessus_ATCC_199      --AAELPGL---------VHVETEAERVARFERDALPLLDQLYGA-----
TH_4436|M.thermoresistible__bu      -MTASIPSA----------RIQPDSALKARFAAEVGPLIDVLSRG-----
MSMEG_1690|M.smegmatis_MC2_155      --MTLPPDL---------DDLESEAELTARFIRDAMPYQPSLLRT-----
Mvan_5003|M.vanbaalenii_PYR-1       TMTISTPADR------ETATADSDPELAARFEREALPLRDVLLRG-----
MLBr_01076|M.leprae_Br4923          TIMSHPPPSRDDDWVEPFDALQGTAVFDATGDKATMPSWEELVRQHAARV
                                                         :      *     . *    *        

Mb3250c|M.bovis_AF2122/97           ---ALRMTRNPADAEDLLQETMVKAYAGFRSFRHGTNLKAWLYRILTNTY
Rv3223c|M.tuberculosis_H37Rv        ---ALRMTRNPADAEDLLQETMVKAYAGFRSFRHGTNLKAWLYRILTNTY
MMAR_1334|M.marinum_M               ---ALRMTRNPADAEDLLQETMVKAYAGFRSFREGTNLKAWLYRILTNTY
MUL_2545|M.ulcerans_Agy99           ---ALRMTRNPADAEDLLQETMVKAYAGFRSFREGTNLKAWLYRILTNTY
MAV_4171|M.avium_104                ---ALRMTRNPADAEDLLQETMVKAYAGFRSFRAGTNLKAWLYRILTNTY
Mflv_4689|M.gilvum_PYR-GCK          ---ALRMTRNPADAEDLLQETMVKAYSGFRSFREGTNLKAWLYRILTNTY
MAB_3543c|M.abscessus_ATCC_199      ---ALRMTRNPADAEDLVQETMVKAYAGFGTFKEGTNLKAWLYRILTNTY
TH_4436|M.thermoresistible__bu      ---ARRLARTDADAEDLLQDTLMRAFVGFGSFEEGTNLKAWLFCIQHNQW
MSMEG_1690|M.smegmatis_MC2_155      ---ARRLARTEADAEDLVQDALLNAYVGFRRFRPGTNLRAWLFRIMHNRW
Mvan_5003|M.vanbaalenii_PYR-1       ---ARRLTTNEADAEDLLQDTLLAAYKGFRTFTPGTNIQAWLFRIMQNRW
MLBr_01076|M.leprae_Br4923          YWLAYRLSGNQHDAEDLTQETFIRVFRSVQNYQPGT-FEGWLHRITTNLF
                                       * *:: .  ***** *:::: .: ..  :  ** :..**. *  * :

Mb3250c|M.bovis_AF2122/97           INSYRKKQRQPAEYPTEQITDWQLASNAEHSSTGLRSAEVEALEALPDTE
Rv3223c|M.tuberculosis_H37Rv        INSYRKKQRQPAEYPTEQITDWQLASNAEHSSTGLRSAEVEALEALPDTE
MMAR_1334|M.marinum_M               INSYRKKQRQPAEYPTDEITDWQLASNAEHSSTGLRSAEVEALEALPDTE
MUL_2545|M.ulcerans_Agy99           INSYRKKQRQPAEYPTDEITDWQLASNAEHSSTGLRSAEVEALEALPDTE
MAV_4171|M.avium_104                INSYRKKQRQPAEYPTEEITDWQLASNAEHSSTGLRSAEVEALESLPDSE
Mflv_4689|M.gilvum_PYR-GCK          INSYRKKQRQPAEYPTEEITDWQLAANAEHTSTGLRSAEVEALELLPDSE
MAB_3543c|M.abscessus_ATCC_199      INIYRKKQRQPAEYPTEEITDWQLAANAEHTSTGLRSAEIEALDGLPDDE
TH_4436|M.thermoresistible__bu      INDHRRRQRRPAEVSLDVLTDREVANHDTHARTAAPSAEREVLESLPDSG
MSMEG_1690|M.smegmatis_MC2_155      ISTHRMTQRRPATFCVDEVTDGDLAAGALHVSLGWRSAEDEALDTIPDAH
Mvan_5003|M.vanbaalenii_PYR-1       INNFRRKQRRVDEVTMDGITEGALAAGTRRAPAAPHSVEAELFGGIADDD
MLBr_01076|M.leprae_Br4923          LDMVRRRAR---------IRMDALPDDYDRVPADEPNPEQIYHDSRLGPD
                                    :.  *   *         :    :.    :      . *        .  

Mb3250c|M.bovis_AF2122/97           IKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQ
Rv3223c|M.tuberculosis_H37Rv        IKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQ
MMAR_1334|M.marinum_M               IKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQ
MUL_2545|M.ulcerans_Agy99           IKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQ
MAV_4171|M.avium_104                IKDALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQ
Mflv_4689|M.gilvum_PYR-GCK          IKEALQALPEDFRMAVYYADVEGFPYKEIAEIMETPIGTVMSRLHRGRRQ
MAB_3543c|M.abscessus_ATCC_199      IKEALNKLPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQ
TH_4436|M.thermoresistible__bu      IRAAMEQLSEGSRTVLYYADVEGCTYSETAARMNIPIGTVMSRASRARSQ
MSMEG_1690|M.smegmatis_MC2_155      VRTALDALPEGFRTVVYYADIEGFTYAETAVLMGIPVGTVMSRIARARQR
Mvan_5003|M.vanbaalenii_PYR-1       VTAALGALPEGYRLVLYYAEVEGYTYAETAAILSIPPGTVMSRVYRARQR
MLBr_01076|M.leprae_Br4923          LQAALDSLPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQA
                                    :  *:  *.   * .:  .::** .* * .  :    *** **  *.*  

Mb3250c|M.bovis_AF2122/97           LRGLLAD-VARDRGFARGE--QAHEGVSS
Rv3223c|M.tuberculosis_H37Rv        LRGLLAD-VARDRGFARGE--QAHEGVSS
MMAR_1334|M.marinum_M               LRTLLAD-VAKERGFVRGE--QAHQEVSS
MUL_2545|M.ulcerans_Agy99           LRTLLAD-VAKERGFVRGE--QAHQEVSS
MAV_4171|M.avium_104                LRGLLAD-VAKERGFNRGQ--QTHEEVSS
Mflv_4689|M.gilvum_PYR-GCK          LRELLAG-VARDRGFIRGEQLEAPEEVTS
MAB_3543c|M.abscessus_ATCC_199      LRDLLSE-VAKDRGFLRNN--ELAEGRA-
TH_4436|M.thermoresistible__bu      LRRALQG-MAATTPAA-------------
MSMEG_1690|M.smegmatis_MC2_155      LRAALTEDAALNQDTEVTDNTQASADCAA
Mvan_5003|M.vanbaalenii_PYR-1       LRIALAH-KAVGRGAELDD------EIAA
MLBr_01076|M.leprae_Br4923          LRDYLLT--AHPRDGATTDATHVKSA---
                                    **  *    *