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TLPPDLDDLESEAELTARFIRDAMPYQPSLLRTARRLARTEADAEDLVQDALLNAYVGFRRFRPGTNLRA WLFRIMHNRWISTHRMTQRRPATFCVDEVTDGDLAAGALHVSLGWRSAEDEALDTIPDAHVRTALDALPE GFRTVVYYADIEGFTYAETAVLMGIPVGTVMSRIARARQRLRAALTEDAALNQDTEVTDNTQASADCAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1690 | - | - | 100% (210) | putative ECF sigma factor RpoE1 |
| M. smegmatis MC2 155 | MSMEG_1914 | - | 3e-51 | 53.55% (183) | RNA polymerase sigma-70 factor, family protein |
| M. smegmatis MC2 155 | MSMEG_0573 | - | 8e-45 | 51.11% (180) | putative ECF sigma factor RpoE1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3250c | sigH | 2e-50 | 52.78% (180) | RNA polymerase sigma factor RpoE |
| M. gilvum PYR-GCK | Mflv_4689 | - | 3e-51 | 55.11% (176) | ECF subfamily RNA polymerase sigma-24 factor |
| M. tuberculosis H37Rv | Rv3223c | sigH | 2e-50 | 52.78% (180) | RNA polymerase sigma factor RpoE |
| M. leprae Br4923 | MLBr_01076 | sigE | 4e-16 | 31.05% (219) | RNA polymerase sigma factor SigE |
| M. abscessus ATCC 19977 | MAB_3543c | - | 5e-51 | 53.23% (186) | RNA polymerase sigma-E factor |
| M. marinum M | MMAR_1334 | sigH | 5e-51 | 52.41% (187) | alternative RNA polymerase sigma-E factor (sigma- 24) SigH |
| M. avium 104 | MAV_4171 | - | 1e-51 | 53.89% (180) | RNA polymerase sigma factor RpoE |
| M. thermoresistible (build 8) | TH_0665 | sigH | 9e-50 | 53.33% (180) | ALTERNATIVE RNA POLYMERASE SIGMA-E FACTOR (SIGMA-24) SIGH |
| M. ulcerans Agy99 | MUL_2545 | sigH | 3e-50 | 51.87% (187) | RNA polymerase sigma factor RpoE |
| M. vanbaalenii PYR-1 | Mvan_5003 | - | 3e-52 | 54.64% (194) | ECF subfamily RNA polymerase sigma-24 factor |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3250c|M.bovis_AF2122/97 ----------------------------------------MAD----IDG
Rv3223c|M.tuberculosis_H37Rv ----------------------------------------MAD----IDG
MMAR_1334|M.marinum_M -MSTSTSLLGEERLGRFPASPASVATLSGGTSTEGTVFIKMAD----IDG
MUL_2545|M.ulcerans_Agy99 ----------------------------------------MAD----IDG
MAV_4171|M.avium_104 MVSTATSLLGEEQLAGFLASPGALSVLSGDTAAEGTGFIEMADSPDGPDG
TH_0665|M.thermoresistible__bu ----------------------------------------MTD----IEG
Mflv_4689|M.gilvum_PYR-GCK -------MVPVMAMKAPSRSVFVLDVIGG-AATEGTVFPTMTD----TNG
MAB_3543c|M.abscessus_ATCC_199 --------------MACLERPMSVPIRMVGVATERT---AVTS----MDS
MSMEG_1690|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_5003|M.vanbaalenii_PYR-1 ----------------------------------------------MTMT
MLBr_01076|M.leprae_Br4923 -MGDGIGMEREGRWTGNTQCPLRVVPGDESPTLDGRASPEDLIITNLLSP
Mb3250c|M.bovis_AF2122/97 VTGSAGLQP--------GPSEETDEELTARFERDAIPLLDQLYGG-----
Rv3223c|M.tuberculosis_H37Rv VTGSAGLQP--------GPSEETDEELTARFERDAIPLLDQLYGG-----
MMAR_1334|M.marinum_M VTLAEAPDP--------EPPEETDEQLTARFERDAIPLLDQLYGG-----
MUL_2545|M.ulcerans_Agy99 VTLAEAPDP--------EPPEETDEQLTACFERDAIPLLDQLYGG-----
MAV_4171|M.avium_104 VTSPEVPEAHAEPAAHEETREETDAELTARFERDAIPLLDQLYGG-----
TH_0665|M.thermoresistible__bu TTPIR--------------SEESDAELTARFERDAIPLLDQLYGG-----
Mflv_4689|M.gilvum_PYR-GCK LAASPAPADAG------EAREETDAELTARFERDAIPLLDQLYGG-----
MAB_3543c|M.abscessus_ATCC_199 AAELPGLVH-----------VETEAERVARFERDALPLLDQLYGA-----
MSMEG_1690|M.smegmatis_MC2_155 MTLPPDLDD-----------LESEAELTARFIRDAMPYQPSLLRT-----
Mvan_5003|M.vanbaalenii_PYR-1 ISTPADRET---------ATADSDPELAARFEREALPLRDVLLRG-----
MLBr_01076|M.leprae_Br4923 TIMSHPPPSRDDDWVEPFDALQGTAVFDATGDKATMPSWEELVRQHAARV
: * : ::* *
Mb3250c|M.bovis_AF2122/97 ---ALRMTRNPADAEDLLQETMVKAYAGFRSFRHGTNLKAWLYRILTNTY
Rv3223c|M.tuberculosis_H37Rv ---ALRMTRNPADAEDLLQETMVKAYAGFRSFRHGTNLKAWLYRILTNTY
MMAR_1334|M.marinum_M ---ALRMTRNPADAEDLLQETMVKAYAGFRSFREGTNLKAWLYRILTNTY
MUL_2545|M.ulcerans_Agy99 ---ALRMTRNPADAEDLLQETMVKAYAGFRSFREGTNLKAWLYRILTNTY
MAV_4171|M.avium_104 ---ALRMTRNPADAEDLLQETMVKAYAGFRSFRAGTNLKAWLYRILTNTY
TH_0665|M.thermoresistible__bu ---ALRMTRNPADAEDLLQETMVKAYQGFRSFREGTNLKAWLYRILTNTY
Mflv_4689|M.gilvum_PYR-GCK ---ALRMTRNPADAEDLLQETMVKAYSGFRSFREGTNLKAWLYRILTNTY
MAB_3543c|M.abscessus_ATCC_199 ---ALRMTRNPADAEDLVQETMVKAYAGFGTFKEGTNLKAWLYRILTNTY
MSMEG_1690|M.smegmatis_MC2_155 ---ARRLARTEADAEDLVQDALLNAYVGFRRFRPGTNLRAWLFRIMHNRW
Mvan_5003|M.vanbaalenii_PYR-1 ---ARRLTTNEADAEDLLQDTLLAAYKGFRTFTPGTNIQAWLFRIMQNRW
MLBr_01076|M.leprae_Br4923 YWLAYRLSGNQHDAEDLTQETFIRVFRSVQNYQPGT-FEGWLHRITTNLF
* *:: . ***** *:::: .: .. : ** :..**.** * :
Mb3250c|M.bovis_AF2122/97 INSYRKKQRQPAEYPTEQITDWQLASNAEHSSTGLRSAEVEALEALPDTE
Rv3223c|M.tuberculosis_H37Rv INSYRKKQRQPAEYPTEQITDWQLASNAEHSSTGLRSAEVEALEALPDTE
MMAR_1334|M.marinum_M INSYRKKQRQPAEYPTDEITDWQLASNAEHSSTGLRSAEVEALEALPDTE
MUL_2545|M.ulcerans_Agy99 INSYRKKQRQPAEYPTDEITDWQLASNAEHSSTGLRSAEVEALEALPDTE
MAV_4171|M.avium_104 INSYRKKQRQPAEYPTEEITDWQLASNAEHSSTGLRSAEVEALESLPDSE
TH_0665|M.thermoresistible__bu INNYRKRQRQPAVYPTEEFTDWQLASTAEHSSTGLRSAEVEALEALPDTE
Mflv_4689|M.gilvum_PYR-GCK INSYRKKQRQPAEYPTEEITDWQLAANAEHTSTGLRSAEVEALELLPDSE
MAB_3543c|M.abscessus_ATCC_199 INIYRKKQRQPAEYPTEEITDWQLAANAEHTSTGLRSAEIEALDGLPDDE
MSMEG_1690|M.smegmatis_MC2_155 ISTHRMTQRRPATFCVDEVTDGDLAAGALHVSLGWRSAEDEALDTIPDAH
Mvan_5003|M.vanbaalenii_PYR-1 INNFRRKQRRVDEVTMDGITEGALAAGTRRAPAAPHSVEAELFGGIADDD
MLBr_01076|M.leprae_Br4923 LDMVRRRAR---------IRMDALPDDYDRVPADEPNPEQIYHDSRLGPD
:. * * . *. : . . * . .
Mb3250c|M.bovis_AF2122/97 IKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQ
Rv3223c|M.tuberculosis_H37Rv IKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQ
MMAR_1334|M.marinum_M IKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQ
MUL_2545|M.ulcerans_Agy99 IKEALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQ
MAV_4171|M.avium_104 IKDALQALPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQ
TH_0665|M.thermoresistible__bu IKAALQELPEDFRIAVYLADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQ
Mflv_4689|M.gilvum_PYR-GCK IKEALQALPEDFRMAVYYADVEGFPYKEIAEIMETPIGTVMSRLHRGRRQ
MAB_3543c|M.abscessus_ATCC_199 IKEALNKLPEEFRMAVYYADVEGFPYKEIAEIMDTPIGTVMSRLHRGRRQ
MSMEG_1690|M.smegmatis_MC2_155 VRTALDALPEGFRTVVYYADIEGFTYAETAVLMGIPVGTVMSRIARARQR
Mvan_5003|M.vanbaalenii_PYR-1 VTAALGALPEGYRLVLYYAEVEGYTYAETAAILSIPPGTVMSRVYRARQR
MLBr_01076|M.leprae_Br4923 LQAALDSLPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQA
: ** ** :* .: .::** .* * . : *** **: *.*:
Mb3250c|M.bovis_AF2122/97 LR-GLLADVARDRGFARGEQA--HEGVSS
Rv3223c|M.tuberculosis_H37Rv LR-GLLADVARDRGFARGEQA--HEGVSS
MMAR_1334|M.marinum_M LR-TLLADVAKERGFVRGEQA--HQEVSS
MUL_2545|M.ulcerans_Agy99 LR-TLLADVAKERGFVRGEQA--HQEVSS
MAV_4171|M.avium_104 LR-GLLADVAKERGFNRGQQT--HEEVSS
TH_0665|M.thermoresistible__bu LR-SLLADVARERGIIRDQQAGTPEEVSS
Mflv_4689|M.gilvum_PYR-GCK LR-ELLAGVARDRGFIRGEQLEAPEEVTS
MAB_3543c|M.abscessus_ATCC_199 LR-DLLSEVAKDRGFLRNNEL--AEGRA-
MSMEG_1690|M.smegmatis_MC2_155 LRAALTEDAALNQDTEVTDNTQASADCAA
Mvan_5003|M.vanbaalenii_PYR-1 LR-IALAHKAVGRGAELDDEI------AA
MLBr_01076|M.leprae_Br4923 LRDYLLTAHPRDGATTDATHVKSA-----
** . .