For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_4185 (-)

annotation: putative acyl-CoA dehydrogenase, middle domain protein
coordinates: 263761 - 264891
length: 377

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_4185 - - 100% (377) putative acyl-CoA dehydrogenase, middle domain protein
M. thermoresistible (build 8) TH_4598 - 2e-85 45.79% (380) PUTATIVE putative putative acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_3176 - 1e-82 46.35% (356) PUTATIVE acyl-CoA dehydrogenase domain protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1969c fadE17 7e-79 40.10% (399) acyl-CoA dehydrogenase FADE17
M. gilvum PYR-GCK Mflv_2394 - 5e-88 45.28% (371) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv1934c fadE17 7e-79 40.10% (399) acyl-CoA dehydrogenase FADE17
M. leprae Br4923 MLBr_00737 fadE25 3e-25 25.33% (383) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_0597 - 1e-71 37.37% (380) acyl-CoA dehydrogenase FadE
M. marinum M MMAR_4791 - 4e-85 45.82% (371) acyl-CoA dehydrogenase
M. avium 104 MAV_0865 - 9e-89 47.71% (371) acyl-CoA dehydrogenase middle domain-containing protein
M. smegmatis MC2 155 MSMEG_4874 - 7e-88 46.90% (371) putative acyl-CoA dehydrogenase
M. ulcerans Agy99 MUL_2892 fadE17 3e-70 38.67% (375) acyl-CoA dehydrogenase FadE17
M. vanbaalenii PYR-1 Mvan_4254 - 2e-88 46.09% (371) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb1969c|M.bovis_AF2122/97           ---MDVSYPPEAEAFRDR--------IREFVAEHLPPGWPGPGAL--PPH
Rv1934c|M.tuberculosis_H37Rv        ---MDVSYPPEAEAFRDR--------IREFVAEHLPPGWPGPGAL--PPH
MUL_2892|M.ulcerans_Agy99           ------------------------------MDEHLPCGWSGPGAL--AVQ
MAB_0597|M.abscessus_ATCC_1997      MVESQVSPAPAGEPMSEMSDDQVRTEIREWLAENLVGEFAELKGLGGPGS
Mflv_2394|M.gilvum_PYR-GCK          ---MDFRDSPDEAAFRDR--------LAAWLKEQK--GRFPTSGD-----
Mvan_4254|M.vanbaalenii_PYR-1       ---MDFRDSPEEAAFRDR--------LRGWLSEQK--GKFPTSGD-----
MSMEG_4874|M.smegmatis_MC2_155      ---MDFRDSPEEAAFRDR--------LRSWLADNA--ASFKASGD-----
MMAR_4791|M.marinum_M               ---MDFRDSPQEAVFRQR--------LRNWLSVNA--DDFRGSGD-----
MAV_0865|M.avium_104                ---MDFRDSPDEAAFRER--------LRSWLSLHA--KEFASSGD-----
TH_4185|M.thermoresistible__bu      ---MDLLDSPAEADFRAR--------LRAWLRDNVPAEPEPAALA-----
MLBr_00737|M.leprae_Br4923          --MVGWSGNPLFDLFKLPEEHN---ELRATIRALAEKEIAPHAAD-----
                                                                  :                   

Mb1969c|M.bovis_AF2122/97           EREEFAR--HWRRALAGAGLVAVSWPTEYGGGGLSPMEQVVLAEEFARAG
Rv1934c|M.tuberculosis_H37Rv        EREEFAR--HWRRALAGAGLVAVSWPTEYGGGGLSPMEQVVLAEEFARAG
MUL_2892|M.ulcerans_Agy99           DRKAFAA--RWRQLLVAAGLIAVSWPKEYGGGGYSPVEQVVLAEEFARAG
MAB_0597|M.abscessus_ATCC_1997      EHEAFEERLAWNRHLAAAGWTCLGWPVEHGGRGATVSQRVIFYEEYARAE
Mflv_2394|M.gilvum_PYR-GCK          --AYWAKAGEWHQALFEAGFFGTSWPKAYGGQDLPPVYDVIVDEEIAKAG
Mvan_4254|M.vanbaalenii_PYR-1       --AYWAKAGEWHQALFGAGFFGTSWPKEYGGQDLPPVYDVIVDEEIAKAG
MSMEG_4874|M.smegmatis_MC2_155      --DYWARQGEWHQALYGAGFFGTSWPKEFGGQDLPPVYDVIVDEELARAG
MMAR_4791|M.marinum_M               --QYWARQAHWHQALYREGFFGLSWPREYGGRELAPVYDVIVDEELARAG
MAV_0865|M.avium_104                --DYWARQAEWHQALYREGFFGLSWPREYGGQELAPVYDVIVDEELARAG
TH_4185|M.thermoresistible__bu      --DRWPGMRAFQKKMYEGGWVALSWPKEYGGQGLGPMEEAILSEELGRTN
MLBr_00737|M.leprae_Br4923          VDQRARFPEEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVD
                                                  :   *      *  .**         :. ** .:. 

Mb1969c|M.bovis_AF2122/97           APERAENDLLGIDLLGNTLIALGSEAQKRHFLPRILSGEHRWCQGFSEPE
Rv1934c|M.tuberculosis_H37Rv        APERAENDLLGIDLLGNTLIALGSEAQKRHFLPRILSGEHRWCQGFSEPE
MUL_2892|M.ulcerans_Agy99           APEREENDLFGVDLLCNTLIALGTEAQKRHFLPRILTGDDRWCQGFSEPE
MAB_0597|M.abscessus_ATCC_1997      APHKVNH--LGEELLGPTLIAYGTPEQQQRFLPAIRDVTELWCQGYSEPG
Mflv_2394|M.gilvum_PYR-GCK          APARPSLG-----YLVVGLSHHGSEELRQRFLPGMINGTERWCQGFSEPG
Mvan_4254|M.vanbaalenii_PYR-1       APARPSLG-----YLVVGLSHHGSEELRQRFLPGMINGSERWCQGFSEPG
MSMEG_4874|M.smegmatis_MC2_155      APPRPSLG-----YLVVGLGHHGSKELQQRFLPGMINGTERWCQGFSEPG
MMAR_4791|M.marinum_M               APPRPSVG-----YLVFGIGRHGSDALRQRFLPGIIDGTERWCQGFSEPG
MAV_0865|M.avium_104                APPRPSVG-----YLIYGIGRHASDELRRRFLPGIINGTERWCQGFSEPG
TH_4185|M.thermoresistible__bu      APTTIPVS-----HLGRPILSHGTEEQRRRYLPPLLSGDEIWCQGFSEPG
MLBr_00737|M.leprae_Br4923          ASASLIPAVN--KLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSERE
                                    *.                :   .:   ::: ** :       . . **  

Mb1969c|M.bovis_AF2122/97           AGSDLASVRTRGVLDGDEWVINGHKIWTSAGTTANWIFLLARTDPSAAKH
Rv1934c|M.tuberculosis_H37Rv        AGSDLASVRTRGVLDGDEWVINGHKIWTSAGTTANWIFLLARTDPSAAKH
MUL_2892|M.ulcerans_Agy99           AGSDLASVRTRAVLDGDQWVINGQKIWTSAGSTANWIFVLARTDPVAPKH
MAB_0597|M.abscessus_ATCC_1997      AGSDLANVSTSAVLDGGDWVINGQKVWTSLALQSQWCFVVARTEPGSSRH
Mflv_2394|M.gilvum_PYR-GCK          AGSDLASLTTTAVKDGDEYVIHGHKIWTSYSDVADWCLVLARTDKDVPKH
Mvan_4254|M.vanbaalenii_PYR-1       AGSDLASLTTTAVRDGDEYVIHGHKIWTSYSDVADWCLLLARTDKDVPKH
MSMEG_4874|M.smegmatis_MC2_155      AGSDLASLITTATRDGDNYIINGHKIWTSYSDVADWCLLLARTDKDVPRH
MMAR_4791|M.marinum_M               AGSDLAALTTTATRVGDDYVVHGHKIWTSYSDVAEWCLLLARTEPGASRH
MAV_0865|M.avium_104                AGSDLASLTTTARLEGDTYVVDGHKIWTSYSDVADWCLLLARTDPQAKRH
TH_4185|M.thermoresistible__bu      AGSDLASLRTKAVRDGDDYVITGHKTWTSLGAYADYCLLLARTDDAAPRH
MLBr_00737|M.leprae_Br4923          AGSDAASMRTRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGAN
                                    **** * : * .   *. ::: * * * : .  : :  ::* *:     :

Mb1969c|M.bovis_AF2122/97           RGLSFLLVPMDQPGVVVRPIVNAAG--HSSFSEVFLTDARTSAGNVVGRV
Rv1934c|M.tuberculosis_H37Rv        RGLSFLLVPMDQPGVVVRPIVNAAG--HSSFSEVFLTDARTSAGNVVGRV
MUL_2892|M.ulcerans_Agy99           QGLSLLLVPMDQPAVVVRPIVNAAG--HSLFNEVFFADARTGVANVVGEV
MAB_0597|M.abscessus_ATCC_1997      KGLSYLLVPLDQPGVEIRPIIQLTG--TSEFNEVFFDNARTSADLVVGEP
Mflv_2394|M.gilvum_PYR-GCK          KGISAFIVSMHQPGIEQRPLKMISGV-TKEFGQVSFDGARVPAENMVGAP
Mvan_4254|M.vanbaalenii_PYR-1       KGISAFIVNMHQAGIEQRPLKMISGV-TKEFGQVSFDGARVPAENMVGAP
MSMEG_4874|M.smegmatis_MC2_155      KGISAFIISMHQDGIQQRPLKMINGV-TTEFGQVTFDNAVVPASHMVGAP
MMAR_4791|M.marinum_M               RGLSAFVVAMKQPGVQQRPLRMMNGV-TKEFGQVFFDGATVAADRMVGAP
MAV_0865|M.avium_104                RGLSAFILEMKQPGVQQRPLRMINGV-TNEFGQVFFDGAKVPADRMVGAP
TH_4185|M.thermoresistible__bu      RGISAFILPLDLPGVEVRPIVLANG--DEEFAEIHLDGARVPAANMLGAP
MLBr_00737|M.leprae_Br4923          -GISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEP
                                     *:* :::  .  ..   *     *       :: :  .      ::*  

Mb1969c|M.bovis_AF2122/97           GDGWSTAMTLLGFERGSHIATAAIDFERDLQRLCELARDR-----GLHTD
Rv1934c|M.tuberculosis_H37Rv        GDGWSTAMTLLGFERGSHIATAAIDFERDLQRLCELARDR-----GLHTD
MUL_2892|M.ulcerans_Agy99           GSGWTAAMSLLGFERGAQATTGAIDFARDLSRLCDLARAR-----GLDSD
MAB_0597|M.abscessus_ATCC_1997      GDGWRVAMGTLTFERGVSTLGNQITYARELSRLAELAKSN-----GAADD
Mflv_2394|M.gilvum_PYR-GCK          GEGWKLAMTVVSHEREPSTLGFSARYG----KTVRQMAAG-----VDG--
Mvan_4254|M.vanbaalenii_PYR-1       GEGWKLAMTVVSHEREPSTLGFSARYG----KTVRQMASR-----LDG--
MSMEG_4874|M.smegmatis_MC2_155      GEGWALAMTVVSHEREPSTLGYSARYG----KLVREMASR-----VEG--
MMAR_4791|M.marinum_M               GDGWAVAMTVVGHEREPSTLGYAARYN----KLVAELLAR-----NHAQG
MAV_0865|M.avium_104                GDGWAVAMTVVGHEREPSTLGYAARYG----KIVRSLYAR-----TDG--
TH_4185|M.thermoresistible__bu      TDGWKIAMEVVSYERGAVDIGYQAKFEHAFAELVTELADR-----RDDP-
MLBr_00737|M.leprae_Br4923          GTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTF
                                      *:  *:  : . *                                   

Mb1969c|M.bovis_AF2122/97           PRVRDGLAWCYARVQIMRYRGYRDLTLALTGRP-PGAEAAITKVIWSEYF
Rv1934c|M.tuberculosis_H37Rv        PRVRDGLAWCYARVQIMRYRGYRDLTLALTGRP-PGAEAAITKVIWSEYF
MUL_2892|M.ulcerans_Agy99           PRIRDRLAWCYSRTQIMRYRGYCSLTWALNGVL-PGAEAAISKVIWSEYF
MAB_0597|M.abscessus_ATCC_1997      PAIRERLAQAYVGMRTMRAYALATMDEERPG------QDNVSKLLWANWH
Mflv_2394|M.gilvum_PYR-GCK          -TPPDELSWAWVQTEMLRLHVRRRLSEQLDGLT-HGPQGSLDKLLMTWVE
Mvan_4254|M.vanbaalenii_PYR-1       -APNQELLWAWVQTEMLRLHVRRRLSEQLDGLT-HGPQGSLDKLLMTWVE
MSMEG_4874|M.smegmatis_MC2_155      -RAPQDLAWAAVQAEMLRLHVRRRLSEQLDGLK-HGPQGSLDKLLMTWVE
MMAR_4791|M.marinum_M               HPVSDELAWAAVQAEMLTHHVRRRLSEQLDGVS-HGPEGSLDKLLMTWVE
MAV_0865|M.avium_104                -PVCEELAWAAVQSEMLTHHVRRRLSEQLDGVS-HGPEGSLDKLLMTWVE
TH_4185|M.thermoresistible__bu      -AVLRRIGRIAANLEVLRMHSLRSLSARVAGGA-PGPESSIDKLLMTEVE
MLBr_00737|M.leprae_Br4923          QSIQFMLADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIA
                                          :       .               *           * : :   

Mb1969c|M.bovis_AF2122/97           RRYTDLAVEILGLEALGPRGPGNGGARLVPEAGTPNSPACWMDELLYARA
Rv1934c|M.tuberculosis_H37Rv        RRYTDLAVEILGLEALGPRGPGNGGARLVPEAGTPNSPACWMDELLYARA
MUL_2892|M.ulcerans_Agy99           QRYTELAVEILGLDALCPSGPGNGEARVVPQAGTANSPACWMDELLYARA
MAB_0597|M.abscessus_ATCC_1997      RDLGELAMEIIGTSTLLTN------------AGEMDE---WQRLFLFSRA
Mflv_2394|M.gilvum_PYR-GCK          QSVGHAALKTVGTG-----------------------DEELFGAYMYSRA
Mvan_4254|M.vanbaalenii_PYR-1       QSVGHAALATVGTS-----------------------DEELFGAYMYSRA
MSMEG_4874|M.smegmatis_MC2_155      QSVGHAALAVSGTS-----------------------DPELLSAYLYSRA
MMAR_4791|M.marinum_M               QSVGHAALGIAGTH-----------------------DPELFGAYLYSRA
MAV_0865|M.avium_104                QSVGHAALAVAGTR-----------------------DPDLLSAYLYSRA
TH_4185|M.thermoresistible__bu      QHLMGASLELLRDRR-------------------AHPRSEWFDRYLYGRA
MLBr_00737|M.leprae_Br4923          MEVTTDAVQLFGGAG-------------------YTSDFPVERFMRDAKI
                                          ::                                       .: 

Mb1969c|M.bovis_AF2122/97           ATIYAGSSQIQRNVIGERLLGLPKEPRPEVLC
Rv1934c|M.tuberculosis_H37Rv        ATIYAGSSQIQRNVIGERLLGLPKEPRPEVLC
MUL_2892|M.ulcerans_Agy99           ATIYAGSSQIQRNVIGEQLLGLPKEPRREAVH
MAB_0597|M.abscessus_ATCC_1997      DTIYGGSNEIQRNIISERVLGLPREAR-----
Mflv_2394|M.gilvum_PYR-GCK          QSVMGGTSQIQKNIIAQRILGLR---------
Mvan_4254|M.vanbaalenii_PYR-1       QSVMGGTSQIQKNIIAQRILGLGA--------
MSMEG_4874|M.smegmatis_MC2_155      QSVMGGTSQIQKNIIASRILGLGV--------
MMAR_4791|M.marinum_M               QSVMGGTSQIQKNIIASRILGLGV--------
MAV_0865|M.avium_104                QSVMGGTSQIQKNIIASRILGL----------
TH_4185|M.thermoresistible__bu      GSIYGGSAQIQKNILAQRVLGLPREPQA----
MLBr_00737|M.leprae_Br4923          TQIYEGTNQIQRVVMSRALLR-----------
                                      :  *: :**: ::.  :*

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_4185	-	-	100% (377)	putative acyl-CoA dehydrogenase, middle domain protein
M. thermoresistible (build 8)	TH_4598	-	2e-85	45.79% (380)	PUTATIVE putative putative acyl-CoA dehydrogenase
M. thermoresistible (build 8)	TH_3176	-	1e-82	46.35% (356)	PUTATIVE acyl-CoA dehydrogenase domain protein