For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_4231 (-)

annotation: putative acyl-CoA dehydrogenase
coordinates: 4724317 - 4725480
length: 388

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4231--100% (388)putative acyl-CoA dehydrogenase
M. thermoresistible (build 8)TH_3604-2e-2928.85% (305) PUTATIVE putative acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_2845-1e-2725.81% (372) PUTATIVE acyl-CoA dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1381fadE141e-17679.22% (385) acyl-CoA dehydrogenase
M. gilvum PYR-GCKMflv_1884-6e-3026.32% (380) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37RvRv1346fadE141e-17679.22% (385) acyl-CoA dehydrogenase
M. leprae Br4923MLBr_00737fadE253e-2323.12% (372) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977MAB_1073c-4e-3028.14% (366) acyl-CoA dehydrogenase FadE
M. marinum MMMAR_4532fadE131e-2827.54% (374) acyl-CoA dehydrogenase FadE13
M. avium 104MAV_2876-1e-16975.32% (385) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155MSMEG_2130-0.083.77% (382) putative acyl-CoA dehydrogenase
M. ulcerans Agy99MUL_4704fadE134e-2827.61% (326) acyl-CoA dehydrogenase FadE13
M. vanbaalenii PYR-1Mvan_1944-1e-17879.27% (386) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb1381|M.bovis_AF2122/97            -------------MTAG--------SDLDDFRGLLAKAFDERVVAWTAEA
Rv1346|M.tuberculosis_H37Rv         -------------MTAG--------SDLDDFRGLLAKAFDERVVAWTAEA
MAV_2876|M.avium_104                ----------MTTLSAAT------TADIDHYRTVLAGAFDDQVLEWTREA
TH_4231|M.thermoresistible__bu      -------------MTAVS------ETSVDDYRDLLGRVFDERVTAWTAEA
MSMEG_2130|M.smegmatis_MC2_155      -------------MTASAPALTPSTTTVEEYRELLDRVFDDQVTQWTAEA
Mvan_1944|M.vanbaalenii_PYR-1       -------------MTVSM------DVDIDGYRELLSEVFDEQVTAWTAEA
MMAR_4532|M.marinum_M               ---------MSIWN---------TPERE-ELRKTVRSFAEREVLPHIDEW
MUL_4704|M.ulcerans_Agy99           ---------MSIWN---------TPERE-ELRKSVRSFAEREVLPHIDEW
Mflv_1884|M.gilvum_PYR-GCK          ---------MSIWT---------TPERD-DLRRTVRAFAEREVLPFADEW
MAB_1073c|M.abscessus_ATCC_199      ------MTAVNSWN---------TPERK-ALRETVRDFAEREILPNVNEW
MLBr_00737|M.leprae_Br4923          MVGWSGNPLFDLFK---------LPEEHNELRATIRALAEKEIAPHAADV
                                                                   *  :    : .:     : 

Mb1381|M.bovis_AF2122/97            EAQERFPRQLIEHLGVCGVFDAKWATD---ARPDVGKLVELAFALGQLAS
Rv1346|M.tuberculosis_H37Rv         EAQERFPRQLIEHLGVCGVFDAKWATD---ARPDVGKLVELAFALGQLAS
MAV_2876|M.avium_104                EARQRFPRELIEHLGARGVFSEKWCGG---MLPDVGKLVELARALGRLSS
TH_4231|M.thermoresistible__bu      EETERFPRALIEYLGRSGVFAEKWQDH---QLPDVAKLIELALALGRLGS
MSMEG_2130|M.smegmatis_MC2_155      EETERFPRQLIEHLGRNGVFTEKWGDA---QQPDVAKLIELAFSLGRLGS
Mvan_1944|M.vanbaalenii_PYR-1       VASERFPRKLIEHLGAAGVFRSKWGPAGG-QHPDVAKLNELAFRLGHLGS
MMAR_4532|M.marinum_M               ERTGELPRDLHRRAGAAGLLGAGLPESAGGGGGDGADSVIICEQMHQSGA
MUL_4704|M.ulcerans_Agy99           ERTGELPLDLHRRAGAAGLLGAGLPESAGGGGGDGADSVIICEQMHQSGA
Mflv_1884|M.gilvum_PYR-GCK          ERAREIPRDLHRAAAAAGLLGAGFPEEVGGDGGDGADAVVICEEMHESGC
MAB_1073c|M.abscessus_ATCC_199      EREGLLPRELHRKAGDLGLLGPGSPEAVGGGGGDAIDPVIVCEELHYAGV
MLBr_00737|M.leprae_Br4923          DQRARFPEEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDA
                                         :*          *.              *      :   :     

Mb1381|M.bovis_AF2122/97            AG-IGVGVSLHDSAIAILRRFGKSDYLRDICDQAIRGAAVLCIGASEESG
Rv1346|M.tuberculosis_H37Rv         AG-IGVGVSLHDSAIAILRRFGKSDYLRDICDQAIRGAAVLCIGASEESG
MAV_2876|M.avium_104                AG-IGVGVSLHDSAIAVLRRFGKSDYLRDICERAIAGQAVLCIGASEESG
TH_4231|M.thermoresistible__bu      AG-IGVGVSLHDSAIAILRRFGRSDHLREIAEQAIRGEAVLCIGASEESG
MSMEG_2130|M.smegmatis_MC2_155      AG-IGVGVSLHDSAICVLRRFGRSDYLRNICEQAIRGEAVLCIGASEESG
Mvan_1944|M.vanbaalenii_PYR-1       AG-IGVGVSLHDSAIAVLRRFGRSDHLKAVCEQAIDGEAVLCIGASEESG
MMAR_4532|M.marinum_M               PGGVFASLFTCGIAVPHMIASGDERLIEEFVRPTLAGDKIGALAITEPGG
MUL_4704|M.ulcerans_Agy99           PGGVFASLFTCGIAVPHMIASGDERLIEEFVRPTLAGNKIGALAITEPGG
Mflv_1884|M.gilvum_PYR-GCK          PGGVFASLFTSGIAVPHMIASQDERLIDTYVRPTLRGENIGSLAITEPGG
MAB_1073c|M.abscessus_ATCC_199      PGGVFASLFTCGISTPHMIASGDQRLIDNYVKPTLAGELIGSLAITEPGG
MLBr_00737|M.leprae_Br4923          SASLIPAVNKLGTMG--LILRGSEELKKQVLPSLAAEGAMASYALSEREA
                                    .. :  .:   .     :     .               : . . :*  .

Mb1381|M.bovis_AF2122/97            GSDLQIVETEIRSRDGGFEVRGVKKFVSLSPIADHIMVVARSVDHDPTSR
Rv1346|M.tuberculosis_H37Rv         GSDLQIVETEIRSRDGGFEVRGVKKFVSLSPIADHIMVVARSVDHDPTSR
MAV_2876|M.avium_104                GSDLQIVRTEMSSRDGGFDVRGVKKFVSLSPIADHIMVVARSIDHDSASK
TH_4231|M.thermoresistible__bu      GSDLQIVETEVRSEGDGFRVRGTKKFVSLSPIADHIVVVARSVDHDPSSR
MSMEG_2130|M.smegmatis_MC2_155      GSDLQIVETEVRSARGGFEVKGIKKFVSLSPIADHIIVVARGVDHDPTSR
Mvan_1944|M.vanbaalenii_PYR-1       GSDLQIVETEVRSAREGFEIRGIKKFVSLSPIADHIIVVARGVDHDPTSR
MMAR_4532|M.marinum_M               GSDVGHLRTSAVRDGDHFIVNGAKTYITSGVR-ADFVVTAVRTGG-PGAG
MUL_4704|M.ulcerans_Agy99           GSDVGHLRTSAVREGDHFIVNGAKTYITSGVR-ADFVVTAVRTGG-PGAG
Mflv_1884|M.gilvum_PYR-GCK          GSDVGHLTTRAVRDGDCFIVNGAKTYITSGVR-ADYVVTAARTGG-PGAA
MAB_1073c|M.abscessus_ATCC_199      GSDVGHLTTSAKRDGDHYIVNGAKTFITSGVR-ADYVVTAVRTGG-PGAA
MLBr_00737|M.leprae_Br4923          GSDAASMRTRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPD-KGAN
                                    ***   : *        : :.* * ::: .       * *        : 

Mb1381|M.bovis_AF2122/97            HGNVAVVAVPAAQVSVQTPYRKVGAGPLDTAAVCID-TWVPADALVARAG
Rv1346|M.tuberculosis_H37Rv         HGNVAVVAVPAAQVSVQTPYRKVGAGPLDTAAVCID-TWVPADALVARAG
MAV_2876|M.avium_104                HGNVALIAVPTSQVSVQRPYAKVGAGPLDTAAVHID-TWVPADALVARAG
TH_4231|M.thermoresistible__bu      HGNVMLIAVPTTQVEVQTPYRKVGAGPLDTAAVHID-TWVPGDALIARPG
MSMEG_2130|M.smegmatis_MC2_155      HGNVLVIAVPTSQCEVQTPYRKVGAGPLDTAAVHID-TWVPEQALVARAG
Mvan_1944|M.vanbaalenii_PYR-1       HGNVLVVAVPTRQVEIQTPYRKVGAGPLDTAAVHID-TWVPADHLVARAG
MMAR_4532|M.marinum_M               GVSLLVVEKGTPGFVVSRKLDKMGWRSSDTAELSYTDARVPAANLVGAEN
MUL_4704|M.ulcerans_Agy99           GVSLLVVEKGTPGFVVSRKLDKMGWRSSDTAELSYTDARIPAANLVGAEN
Mflv_1884|M.gilvum_PYR-GCK          GISLIVVDKGTPGFAVSRKLDKMGWRSSDTAELSYTDVRVPAANVVGAEN
MAB_1073c|M.abscessus_ATCC_199      GVSLLLIDKDTPGFEVARKLDKMGWRSSDTAELSFTDVRVPAENLVGSEN
MLBr_00737|M.leprae_Br4923          GISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPG
                                      .  ::        :     *:*     *: :      :*   ::.  .

Mb1381|M.bovis_AF2122/97            TGLAAISWGLAHERMSIAGQIAASCQRAIGITLARMMSRRQFGQTLFEHQ
Rv1346|M.tuberculosis_H37Rv         TGLAAISWGLAHERMSIAGQIAASCQRAIGITLARMMSRRQFGQTLFEHQ
MAV_2876|M.avium_104                TGLAAISWGLAHERMSIAGQIAASCQRAIGITLARMMTRRQFGRTLFEHQ
TH_4231|M.thermoresistible__bu      TGLAAISWGLAHERLSIAGQVAAGCQRVIGITLARMMKRRQFGSTLYEHQ
MSMEG_2130|M.smegmatis_MC2_155      TGLAAISWGLAHERMSIAGQVASGSQRILGITLARMMKRRQFGHTLYEHQ
Mvan_1944|M.vanbaalenii_PYR-1       TGLAAISWGLAHERMSIAGQVASSCQRVLGVTHARMVQRRQFGATLFEHQ
MMAR_4532|M.marinum_M               SGFAQIAQAFVSERIALAAQAYSSAQRCLDITVQWCRDRETFGRPLISRQ
MUL_4704|M.ulcerans_Agy99           SGFAQIAQAFVSERIALAAQAYSSAQRCLDITVQWCRDRETFGRPLISRQ
Mflv_1884|M.gilvum_PYR-GCK          TGFLQIAAAFVSERVGLAAQAYSSAQRCLDLTVEWCRNRQTFGKPLIARQ
MAB_1073c|M.abscessus_ATCC_199      TGFAQIAGAFVSERIGLAAQAYASAQRCLDLTVEWCRNRETFGRPLISRQ
MLBr_00737|M.leprae_Br4923          TGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQ
                                    :*:      :   *  :..*  . .*  :. :      *. ** .:   *

Mb1381|M.bovis_AF2122/97            ALRLRMADLQARVDLLRYALHGIAE---QGRLELR-TAAAVKVTAARLGE
Rv1346|M.tuberculosis_H37Rv         ALRLRMADLQARVDLLRYALHGIAE---QGRLELR-TAAAVKVTAARLGE
MAV_2876|M.avium_104                ALRLRMADLQARVDLLQHGLNGIAA---QGRLDLR-AAAGVKVTAARLGE
TH_4231|M.thermoresistible__bu      ALRMRMADLQARTDMLRFALTGIAT---QGRLDLR-TAAAIKVSAARLGE
MSMEG_2130|M.smegmatis_MC2_155      ALRMRMADLQARVDMLRYGLAGIAA---GGKLDLR-AAAAFKVTAARLGE
Mvan_1944|M.vanbaalenii_PYR-1       ALRIRMADLQARVDLLRHALTGIAA---QGRLDLR-AAAGVKVTAARLGE
MMAR_4532|M.marinum_M               SVQNTLAEMARRIDVARVYSRSVVERQLAGEHDLIPQVCFAKNTAVEAGE
MUL_4704|M.ulcerans_Agy99           SVQNTLAEMARRIDVARVYSRSVVERQLAGEHDLIPQVCFAKNTAVEAGE
Mflv_1884|M.gilvum_PYR-GCK          TVQSTLAEMARRIDVARVYTRHVVERQLAGDADLITEVCFAKNTAVEAGE
MAB_1073c|M.abscessus_ATCC_199      SVQNTLAEMARRIDVARVYTHALVDRAIAGESNLIAEVCFAKNTAVEAGE
MLBr_00737|M.leprae_Br4923          SIQFMLADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAM
                                    :::  :*::  : :  :      .     *  :*    .  *  *   . 

Mb1381|M.bovis_AF2122/97            EVISECMHIFGGAGYLVDETTLGKWWRDMKLARVGGGTDEVLWELVAAGM
Rv1346|M.tuberculosis_H37Rv         EVISECMHIFGGAGYLVDETTLGKWWRDMKLARVGGGTDEVLWELVAAGM
MAV_2876|M.avium_104                EVMSECMHIFGGAGYLVEETPLGRWWRDMKLARVGGGTDEVLWELVAAGM
TH_4231|M.thermoresistible__bu      EVLSECMHIFGGSGYLVDETPLGRWWRDMKLARVGGGTDEVLWELVAAAM
MSMEG_2130|M.smegmatis_MC2_155      EVISECMHIFGGSGYLVDETPLGKWWRDMKLARVGGGTDEVLWELVAAAM
Mvan_1944|M.vanbaalenii_PYR-1       EVLSECMHIFGGAGYLVDETPLGRWWRDMKLARVGGGTDEVLWELVAAAM
MMAR_4532|M.marinum_M               WVANQAVQLFGGMGYMAES-EIERQYRDMRILGIGGGTTEILTALAAKLL
MUL_4704|M.ulcerans_Agy99           WVANQAVQLFGGMGYMAES-EIERQYRDMRILGIGGGTTEILTALAAKLL
Mflv_1884|M.gilvum_PYR-GCK          WVANQAVQLFGGMGYMTES-EVERQYRDMRILGIGGGTTEILTSLAAKTL
MAB_1073c|M.abscessus_ATCC_199      WVANQGVQLFGGMGYMAES-EIERQYRDMRIIGIGGGTTEILTSLAAKLL
MLBr_00737|M.leprae_Br4923          EVTTDAVQLFGGAGYTSDF-PVERFMRDAKITQIYEGTNQIQRVVMSRAL
                                     * .: :::*** **  :   : :  ** ::  :  ** ::   : :  :

Mb1381|M.bovis_AF2122/97            TPDHDGYAAVVGASKA--
Rv1346|M.tuberculosis_H37Rv         TPDHDGYAAVVGASKA--
MAV_2876|M.avium_104                AADHGGYRSVVGASSA--
TH_4231|M.thermoresistible__bu      KPDYDGYQEIYGADG---
MSMEG_2130|M.smegmatis_MC2_155      KPDYDGYAEFAGPDAV--
Mvan_1944|M.vanbaalenii_PYR-1       KPDFDSYAEMIGGTTASD
MMAR_4532|M.marinum_M               GYQS--------------
MUL_4704|M.ulcerans_Agy99           GYQS--------------
Mflv_1884|M.gilvum_PYR-GCK          GYQT--------------
MAB_1073c|M.abscessus_ATCC_199      GFQS--------------
MLBr_00737|M.leprae_Br4923          LR----------------