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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4191 | - | - | 100% (531) | 3-ketosteroid-delta4 |
| M. thermoresistible (build 8) | TH_4085 | - | 2e-26 | 26.07% (583) | PUTATIVE fumarate reductase/succinate dehydrogenase |
| M. thermoresistible (build 8) | TH_4337 | - | 9e-24 | 26.76% (598) | PUTATIVE fumarate reductase/succinate dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1848 | - | 6e-60 | 32.01% (528) | hypothetical protein Mb1848 |
| M. gilvum PYR-GCK | Mflv_4564 | - | 0.0 | 75.48% (522) | hypothetical protein Mflv_4564 |
| M. tuberculosis H37Rv | Rv1817 | - | 6e-60 | 32.01% (528) | hypothetical protein Rv1817 |
| M. leprae Br4923 | MLBr_00697 | sdhA | 1e-05 | 27.31% (227) | succinate dehydrogenase flavoprotein subunit |
| M. abscessus ATCC 19977 | MAB_0623 | - | 1e-122 | 47.52% (524) | hypothetical protein MAB_0623 |
| M. marinum M | MMAR_0205 | - | 1e-125 | 47.23% (523) | flavoprotein |
| M. avium 104 | MAV_2897 | - | 5e-62 | 33.09% (538) | hypothetical protein MAV_2897 |
| M. smegmatis MC2 155 | MSMEG_2873 | - | 0.0 | 84.19% (525) | hypothetical protein MSMEG_2873 |
| M. ulcerans Agy99 | MUL_4900 | - | 1e-122 | 46.27% (523) | hypothetical protein MUL_4900 |
| M. vanbaalenii PYR-1 | Mvan_3165 | - | 2e-61 | 31.97% (538) | hypothetical protein Mvan_3165 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1848|M.bovis_AF2122/97 MSTDIPATVSAETVTSWSDDVDVTVIGFGIAGGCAAVSAAAAGARVLVLE
Rv1817|M.tuberculosis_H37Rv MSTDIPATVSAETVTSWSDDVDVTVIGFGIAGGCAAVSAAAAGARVLVLE
MAV_2897|M.avium_104 MSTEIPATVSAHDVTSWSDDVDVVVIGFGIAGGCAAVSAAADGARVLVLE
Mvan_3165|M.vanbaalenii_PYR-1 -MQHIPETVNVGDVTSWSDEVDVVVVGFGIAGGCAAVSAAAAGARVLVLE
TH_4191|M.thermoresistible__bu --------------MPTAQEYDVIIVGFGAAGASAAIEAADRGARVLVLD
MSMEG_2873|M.smegmatis_MC2_155 --------------MPTGRDYDVIIVGFGAAGASAAIEAADRGARVLVLD
Mflv_4564|M.gilvum_PYR-GCK -----------------MAEYDVIVVGFGAAGAAAAIEAADRGARVLALD
MMAR_0205|M.marinum_M --------MADDTPEHIVESTDVVVIGFGAAGVSAAITAREQGVQVVALD
MUL_4900|M.ulcerans_Agy99 --------MADDTPEHIVESTDVVVIGFGATGVSAAITAREQGVQVVALD
MAB_0623|M.abscessus_ATCC_1997 --------MPGRS---DMPSADVIIVGYGVAGASAALAALERGASVIILE
MLBr_00697|M.leprae_Br4923 --------------MIQQHRYDVVIVGAGGAGMRAAVEAGPRVRTAVLTK
** ::* * :* **: * .: .
Mb1848|M.bovis_AF2122/97 RAAAAGGTTALAGGHFYLGGGTTVQLATGHPDSPEEMYKYLVAV-SREPD
Rv1817|M.tuberculosis_H37Rv RAAAAGGTTALAGGHFYLGGGTTVQLATGHPDSPEEMYKYLVAV-SREPD
MAV_2897|M.avium_104 RAAAAGGTTSLAGGHFYLGGGTAVQQATGHDDSAEEMYKYLVAV-SREPE
Mvan_3165|M.vanbaalenii_PYR-1 KAAAVGGTTSMAGGHFYLGGGTAVQQATGHDDSAEEMYKYLVSQ-SRDPE
TH_4191|M.thermoresistible__bu RGHGGG-ATAYSGGIVYAGAGTAEQQAGGHADSVENMRAYLARE-VGDAV
MSMEG_2873|M.smegmatis_MC2_155 RGYGGG-ATAYSGGIVYAGAGTPEQHAGGYSDSVENMRAYLEQE-VAGAV
Mflv_4564|M.gilvum_PYR-GCK RGYGGG-ATALSGGIIYAGAGTAEQHAGGHTDSVDNLRAYLTQE-VGDAV
MMAR_0205|M.marinum_M RANGGG-ATAISGGIIYAGGGTAVQQQAGVRDSFEQMLTYLRLE-VADAV
MUL_4900|M.ulcerans_Agy99 RANGGG-ATAISGDIIYAGGGTAVQQQAGVRDSFEQMLTYLRLE-VADAV
MAB_0623|M.abscessus_ATCC_1997 RFDGGG-ASAISGGIYYAGGGTNIQRDAGVEDTPELMLEYLRLE-VGDAV
MLBr_00697|M.leprae_Br4923 LYPTRSHTGAAQGGMCAALANVEDDNWEWHAFDTVKGGDYLADQDAVEIM
. : : *. ... : **
Mb1848|M.bovis_AF2122/97 -HDKIRAYCDGSVEHFNWLEGLGFQFER-SYFPGKAVIQPN-TEGLMFTG
Rv1817|M.tuberculosis_H37Rv -HDKIRAYCDGSVEHFNWLEGLGFQFER-SYFPGKAVIQPN-TEGLMFTG
MAV_2897|M.avium_104 -LDKIRAYCEGSVEHFNWLEDLGFQFER-SYYPGKVVVPPG-TEGLSYTG
Mvan_3165|M.vanbaalenii_PYR-1 -HDKIRAYCEGSVEHFNWLEALGFQFER-SYYPGKVVVPPG-TEGLSYTG
TH_4191|M.thermoresistible__bu SPETLTRFCEQSPAMIEWLKAQGVEFRGGPVPPYKTSYPTD-EHYLYYSG
MSMEG_2873|M.smegmatis_MC2_155 KPETLARFCEQSPALLEWLKAQGVPFRGGAGPSYKTSYPTD-DNYLYYSG
Mflv_4564|M.gilvum_PYR-GCK GEDTLTRFCAESPGLIAWLKAQGVEFRGGPVSSYKTSYPTD-DFYLYYSG
MMAR_0205|M.marinum_M SESTLESFVRGSPGMIDWLSHYGVPFDS-TVCPYKTSFPNN-HYYLYHSG
MUL_4900|M.ulcerans_Agy99 SESTLESFVRGSPEMIDWLSNYGVPFDS-TVYPYKTSFPNN-HYYLYHSG
MAB_0623|M.abscessus_ATCC_1997 KPETLQKFVDGSVDTLNWLQGYGVPFEG-SLAPFKTSYPTD-DYYLYFSG
MLBr_00697|M.leprae_Br4923 CKEAIDAVLDLEKMGMPFNRTPEGRIDQRRFGGHTRDHGKAPVRRACYAA
. : . : : : . .:.
Mb1848|M.bovis_AF2122/97 NEKVWPFLELAVPAPRGHKVPVPGDTGGAAMVIDLLLKRAASLGIQIRYE
Rv1817|M.tuberculosis_H37Rv NEKVWPFLELAVPAPRGHKVPVPGDTGGAAMVIDLLLKRAASLGIQIRYE
MAV_2897|M.avium_104 NEKVWPFCEQAKPAPRGHSVPVPGELGGAAMVIDLLVKRAEALGVQIRYE
Mvan_3165|M.vanbaalenii_PYR-1 NEKVWPFCEQAKPAPRGHSVPVPGELGGAAMVIDLLLKRAADLGVQIRYE
TH_4191|M.thermoresistible__bu NETAFPYSEHAHPAPRGHRALAPGMR-SGRVLFERLRDSALSKGVEFVPL
MSMEG_2873|M.smegmatis_MC2_155 NEKAYPYVDHAQPAPRGHRVLAPGMS-SGRVLFERLRDSALAKGVHFTPL
Mflv_4564|M.gilvum_PYR-GCK NEKAYPYAQHAAPAPRGHRVLAPGMS-SGRVLYERLRDSAKAKGVTVIPL
MMAR_0205|M.marinum_M SENSGAFRSHTPPVQRGHRVKGKGT--SGKQLYAPLAKAALSLGVQFYPH
MUL_4900|M.ulcerans_Agy99 SENSGAFRSHTPPVQRGHRVKGKGN--SGKQLYAPLAKAALSLGVQFYPH
MAB_0623|M.abscessus_ATCC_1997 SESSGMARAATPPRQRGHRAFGRGV--SGKALFAPLADSAERLGADVWRQ
MLBr_00697|M.leprae_Br4923 DRTGHMILQTLYQNCVKHDVEFFNEFYALDLVLTQTPSGPVTTGVVAYEL
... * . . . : . . *
Mb1848|M.bovis_AF2122/97 TGATELIVDGTGKVTGVMWKRFSETGAIKAK-------------------
Rv1817|M.tuberculosis_H37Rv TGATELIVDGTGKVTGVMWKRFSETGAIKAK-------------------
MAV_2897|M.avium_104 TGATNLIVDDDGAVVGVAWKHFTETGAVKAD-------------------
Mvan_3165|M.vanbaalenii_PYR-1 TGVTGLVVDDDGAVVGVRWKHFTETGEVKAK-------------------
TH_4191|M.thermoresistible__bu AHVHSLIQADDGRVTGVRYTVLDPGHRHARR-HRLITRATGKLGTWMPGV
MSMEG_2873|M.smegmatis_MC2_155 AHVHSLIQDEDGRVTGVRYTVTDPGHRNARR-HRRIAKATGKLGTWMPRA
Mflv_4564|M.gilvum_PYR-GCK ARVHGLIT-DAGRVVGVRYRVLDQGHPNAHR-HRVLTRATAKLGTWMPGL
MMAR_0205|M.marinum_M TKVTKLLQDSTGRVTGVEAMTMHDAPPRIRRTYAALAAVSTKPGIYYPPL
MUL_4900|M.ulcerans_Agy99 TKVTKLLQDSTGRVTGVEAMTMHDAPPRIRRAYAALAAVSTKPGIYYPPL
MAB_0623|M.abscessus_ATCC_1997 TRVTGLVVE-EGRVVGVRGMTLKDAPAWARRLYSRLTHYATKPGIYYPPM
MLBr_00697|M.leprae_Br4923 ATGDIHVFHTKAVVIATGGSGRMYKTTSNAH-----TLTGDGIGIVFRKG
: : . * ..
Mb1848|M.bovis_AF2122/97 -------------------------SVIIAAGGFVM--NPDMVAKYTPKL
Rv1817|M.tuberculosis_H37Rv -------------------------SVIIAAGGFVM--NPDMVAKYTPKL
MAV_2897|M.avium_104 -------------------------AVILAAGGFAM--NPQMVAEHTPAL
Mvan_3165|M.vanbaalenii_PYR-1 -------------------------SVVIAAGGFAM--NAEMVAEYTPAL
TH_4191|M.thermoresistible__bu VSGAVRYAERLRAEASVETETRAG-AVILAAGGFIN--NRGWVRQYAPQF
MSMEG_2873|M.smegmatis_MC2_155 VAGAVARGERLRAEAGAEAHASAG-AVILAAGGFIN--DRDWVSRYAPEF
Mflv_4564|M.gilvum_PYR-GCK VNGVVARAERLWAEAAVQTEARAP-SVILAAGGFIF--NREWVQAHAPKF
MMAR_0205|M.marinum_M RNLMERRLRALERRYARAVQIRARRGVIVCAGGFIA--NSEWIKRYAPRY
MUL_4900|M.ulcerans_Agy99 RNLMERRLRALERRYARAVQIRARRGVIVCAGGFIA--NSEWIKRYAPRY
MAB_0623|M.abscessus_ATCC_1997 RKTLEGPAYALERRFAKPFEIRADDGVILSSGGFIA--NRELVRRHAPAY
MLBr_00697|M.leprae_Br4923 LPLEDMEFHQFHPTGLAGLGILISEAVRGEGGRLLNGENERFMEHYAPTI
.* .* : : : ::*
Mb1848|M.bovis_AF2122/97 AEK----------PFVLGNTYDDGLGIRLGVSAGGATQHMDQMFITAPPY
Rv1817|M.tuberculosis_H37Rv AEK----------PFVLGNTYDDGLGIRLGVSAGGATQHMDQMFITAPPY
MAV_2897|M.avium_104 GQPRRTKHHGLVAPYILGNPHDDGLAIRMGVSAGGATKHMDELFITAAAY
Mvan_3165|M.vanbaalenii_PYR-1 AAERKTKHHGTVAPYILGNPNDDGLGIKLGVSAGGVAANLDQLFITAAAY
TH_4191|M.thermoresistible__bu LKI-----------SPLGTVGDDGTGIRLGLDAGGKTDKMGNVTAWRFLS
MSMEG_2873|M.smegmatis_MC2_155 LKI-----------SPLGTVGDDGTGIRLGLDAGGVTDKMGNVTAWRFLS
Mflv_4564|M.gilvum_PYR-GCK TKI-----------SPLGTAGDDGNGIALGLDAGGFTDKMGNVAAWRFLA
MMAR_0205|M.marinum_M VTG-----------LQLGTSGDDGSGIALAQSVGAVTERMDNVSAWRFIT
MUL_4900|M.ulcerans_Agy99 VTG-----------LQLGTSGDDGSGIALAQSVGAVTERMDNVSARRLIT
MAB_0623|M.abscessus_ATCC_1997 LDG-----------LELGTAGDDGTALKLAEPLGAATGHLDEISAWRFIV
MLBr_00697|M.leprae_Br4923 VDLAPR--DIVARSMVLEVLEGRGAGPHKDYVYIDVRHLGEEVLESKLPD
* . * . ::
Mb1848|M.bovis_AF2122/97 PPSILLTGIIVNKLGQRFVAEDSYHSRTA-------GFIMEQPDSAAYLI
Rv1817|M.tuberculosis_H37Rv PPSILLTGIIVNKLGQRFVAEDSYHSRTA-------GFIMEQPDSAAYLI
MAV_2897|M.avium_104 PPEVLLTGIIVNKEGKRFVAEDSYHSRTS-------AFVLEQPEQTAYLI
Mvan_3165|M.vanbaalenii_PYR-1 PPEILLTGVIVNKDGQRFVAEDSYHSRTS-------AFVLEQPEQTAYLI
TH_4191|M.thermoresistible__bu PPSAFLEGLTVGADGRRIANEDLYGATHG-------DVLMREFGGTGWAI
MSMEG_2873|M.smegmatis_MC2_155 PPSAFLEGLTVGADGRRIANEDLYGAAHG-------NVLMREFGGTGWAI
Mflv_4564|M.gilvum_PYR-GCK PLSAFLEGLTVGADGRRITNEDLYGATHS-------NVMMREFGGTGWAI
MMAR_0205|M.marinum_M PPSAFISTVMVDQQGQRVIDESRYGAAVG-------KALVQDHNARAWLV
MUL_4900|M.ulcerans_Agy99 PPSAFISTVMVDQQGQRVIDESRYGAAVG-------KALVHDHNARAWLV
MAB_0623|M.abscessus_ATCC_1997 PPAAFLGSLLVDTKGQRMIDESRYGAALG-------KEIVRTAGGVGYLV
MLBr_00697|M.leprae_Br4923 ITEFSRTYLGVDPVHELVPVYPTCHYVMGGIPTTVTGQVLRDNTSTVPGL
: *. . . . ::. :
Mb1848|M.bovis_AF2122/97 VDEAHLEHPKMPLVPLIDGWE----------------TVVEMEAALGIPP
Rv1817|M.tuberculosis_H37Rv VDEAHLEHPKMPLVPLIDGWE----------------TVVEMEAALGIPP
MAV_2897|M.avium_104 VDEAHTEMPEMPLIRFLDGYE----------------TIAEMEAALGIPA
Mvan_3165|M.vanbaalenii_PYR-1 VDEDHMQMPEMPLIKFVDGFE----------------TIAEIESALGIPD
TH_4191|M.thermoresistible__bu YDAATWRKIRTQITDQTQVFQRLQVWYLLTIGHKKAATIADLARKNGIDA
MSMEG_2873|M.smegmatis_MC2_155 YDAATWRKIKDQITEQTQVFQRLQIWYLRTIGHKKAATIEGIAAKNGIDA
Mflv_4564|M.gilvum_PYR-GCK YDARTWAKIRGQVRTQTQLFQRLQLIYLFTTGHRKSSTLEGLARKNGIDP
MMAR_0205|M.marinum_M ADADLMNEARRQMLKQPLWFQRAQAAALMVADSVRAETLARVARKAGVDP
MUL_4900|M.ulcerans_Agy99 ADADLMNEARRQMLKQPLWFQRAQAAALMVADSVRAETLADVARKAGVEP
MAB_0623|M.abscessus_ATCC_1997 ADQPLVKRARQQLGSQTLWFQRIQAEAFLNVGRKKAGSIEELAAKAGIDP
MLBr_00697|M.leprae_Br4923 YAAGECACVSVHGANRLGTNSLLDINVFGRRSGIAAASYASANDFVDMPP
. : .:
Mb1848|M.bovis_AF2122/97 G-----------NLAATLDRYNAYAARGADPDFHKQPEFLAAQDNGPWGA
Rv1817|M.tuberculosis_H37Rv G-----------NLAATLDRYNAYAARGADPDFHKQPEFLAAQDNGPWGA
MAV_2897|M.avium_104 G-----------NLAATLERYNKFAAAGEDPDFHKQPEYLAAQDNGPWAV
Mvan_3165|M.vanbaalenii_PYR-1 G-----------NLAATLECYNANAAAGVDPDFHKQPEYLAAQDKGPWAV
TH_4191|M.thermoresistible__bu A-----------GLQQTVDEYNRGISSGAGDPGHKHPSLCPPLERGPFYS
MSMEG_2873|M.smegmatis_MC2_155 A-----------ALRKTVDEYNRGIAGGAGDPAHKDPSLCSPMERGPFYS
Mflv_4564|M.gilvum_PYR-GCK A-----------GLRRTVDAYNSGIVSGTGDPAHKDPGLCAPMTTGPFYS
MMAR_0205|M.marinum_M D-----------GLQATVDAHNSAIDAAATDPAGKPAEFVRRVARAPFTL
MUL_4900|M.ulcerans_Agy99 D-----------GLQATVDAHNNVIDAAATDPAGKPAEFVRRVARAPFTL
MAB_0623|M.abscessus_ATCC_1997 E-----------GLARTVSEHNRAIAGGTPDPLGKPDDIRVPIERAPFYL
MLBr_00697|M.leprae_Br4923 NPAEMVISWVANILSEHGNERVADIRGALQQTMDNNAAVFRTEETLKQAL
* . . :
Mb1848|M.bovis_AF2122/97 FDMSLGKAMYA---GFTLG-----GLATSVD-GQVLRDDGAVVAGLYAVG
Rv1817|M.tuberculosis_H37Rv FDMSLGKAMYA---GFTLG-----GLATSVD-GQVLRDDGAVVAGLYAVG
MAV_2897|M.avium_104 FDLSLGRAMYS---GFTIG-----GLAVSVD-GEVQRADGSVVPGLYAAG
Mvan_3165|M.vanbaalenii_PYR-1 FDLSLGRAMYS---GFTMG-----GLTVSID-GEVLREDGSAIPGLYAAG
TH_4191|M.thermoresistible__bu INISADASLFYPIPGLTLG-----GLVVDEDSGAVVHRDGGVIPGLYAAG
MSMEG_2873|M.smegmatis_MC2_155 IDISADSSLFYPIPGLTLG-----GLVVDEDTGAVVHRDGGVVPGLYAAG
Mflv_4564|M.gilvum_PYR-GCK IDISAASSMFYPVPGLTLG-----GLVVDEKTGEVMHRAGGTVAGLYAVG
MMAR_0205|M.marinum_M LNISVRPSLLNPTPMLTLG-----GIKVDEQTGAVLDASGAAIPGLFGAG
MUL_4900|M.ulcerans_Agy99 LNIAVRPSLLNPTPMLTLG-----GIKVDEQTGAVLDASGAAIPGLFGAG
MAB_0623|M.abscessus_ATCC_1997 FNVSIKTNMLNPCPMLTLG-----GLVVDEETGAVQTTSGAAIPGLYAAG
MLBr_00697|M.leprae_Br4923 TDIHSLKERYSRITVHDKGKSFNSDLLEAIELGFLLELAEVTVVGALNRK
:: * .: . * : .: *
Mb1848|M.bovis_AF2122/97 ACASNIAQDGKGYASGTQLGEGSFFGRRAGAHAAARAQGM----------
Rv1817|M.tuberculosis_H37Rv ACASNIAQDGKGYASGTQLGEGSFFGRRAGAHAAARAQGM----------
MAV_2897|M.avium_104 ACASNLAQDGKGYASGTQLGEGSFFGRRAGAHAARRAAKA----------
Mvan_3165|M.vanbaalenii_PYR-1 ACACNIAQDGKGYASGTQLGEGSFFGRRAGEAAARRAGEAAARRAGEAAA
TH_4191|M.thermoresistible__bu RNAVGVCSN--SYVSGLSISDCVFSGRRAGAHAAGGTR------------
MSMEG_2873|M.smegmatis_MC2_155 RTAVGVCSN--SYVSGLSISDCVFSGRRAGADAVAKI-------------
Mflv_4564|M.gilvum_PYR-GCK RTAVGICSN--SYVSGLSLSDCVFSGRRAGAHAAG---------------
MMAR_0205|M.marinum_M RTATGICSN--SYVSGLSIADCVFSGRRAGNHAAIE--------------
MUL_4900|M.ulcerans_Agy99 RTATGICSN--SYVSGLSIADCVFSGRRAGTHAASAALE-----------
MAB_0623|M.abscessus_ATCC_1997 RAAVGICSN--SYVSGLSLADCVFSGRRAGTETGRRIDA-----------
MLBr_00697|M.leprae_Br4923 ESRGGHAREDYPHRDDTNYMRHTMAYKQGTDLLSDIALDFKPVVQTRYEP
. . : : .. . : ::.
Mb1848|M.bovis_AF2122/97 -------------------
Rv1817|M.tuberculosis_H37Rv -------------------
MAV_2897|M.avium_104 -------------------
Mvan_3165|M.vanbaalenii_PYR-1 RRAGEAAARRAGEAAAERA
TH_4191|M.thermoresistible__bu -------------------
MSMEG_2873|M.smegmatis_MC2_155 -------------------
Mflv_4564|M.gilvum_PYR-GCK -------------------
MMAR_0205|M.marinum_M -------------------
MUL_4900|M.ulcerans_Agy99 -------------------
MAB_0623|M.abscessus_ATCC_1997 -------------------
MLBr_00697|M.leprae_Br4923 QERKY--------------