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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4085 | - | - | 100% (582) | fumarate reductase/succinate dehydrogenase flavoprotein domain |
| M. thermoresistible (build 8) | TH_0368 | - | 4e-80 | 37.36% (538) | PROBABLE DEHYDROGENASE |
| M. thermoresistible (build 8) | TH_2946 | - | 3e-77 | 36.22% (566) | PUTATIVE 3-ketosteroid-delta-1-dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3567 | - | 6e-86 | 37.08% (569) | 3-ketosteroid-delta-1-dehydrogenase |
| M. gilvum PYR-GCK | Mflv_2398 | - | 0.0 | 76.99% (539) | fumarate reductase/succinate dehydrogenase flavoprotein |
| M. tuberculosis H37Rv | Rv3537 | - | 6e-86 | 37.08% (569) | 3-ketosteroid-delta-1-dehydrogenase |
| M. leprae Br4923 | MLBr_01226 | nadB | 9e-06 | 42.17% (83) | L-aspartate oxidase |
| M. abscessus ATCC 19977 | MAB_0622c | - | 4e-85 | 36.46% (565) | 3-ketosteroid-delta-1-dehydrogenase |
| M. marinum M | MMAR_4780 | - | 0.0 | 72.49% (538) | dehydrogenase |
| M. avium 104 | MAV_0875 | - | 0.0 | 75.46% (538) | FAD binding domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_4870 | - | 0.0 | 76.85% (540) | FAD binding domain-containing protein |
| M. ulcerans Agy99 | MUL_0349 | - | 0.0 | 71.93% (538) | dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_4248 | - | 0.0 | 78.11% (539) | fumarate reductase/succinate dehydrogenase flavoprotein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3567|M.bovis_AF2122/97 ---------MTVQEFDVVVVGSGAAGMVAALVAAHRGLSTVVVEKAPHYG
Rv3537|M.tuberculosis_H37Rv ---------MTVQEFDVVVVGSGAAGMVAALVAAHRGLSTVVVEKAPHYG
MAB_0622c|M.abscessus_ATCC_199 ---------MTEQEYDVVVVGSGGAGMVAALTAAHNGLSTVLIEKAPHFG
Mflv_2398|M.gilvum_PYR-GCK MTE-------WDHEVDVVVLGSGGAGLTAALAASVNGATVEVYEKAATVG
Mvan_4248|M.vanbaalenii_PYR-1 MTD-------WDHEADVVVLGSGGAGLTAALTAAVNGATVEVYEKAETVG
TH_4085|M.thermoresistible__bu VTE-------WDRETDVIVLGTGGAGLTAALTAVVDGAAVEVFEKAPTVG
MSMEG_4870|M.smegmatis_MC2_155 MTDSNGLHDSFDDEVDVVVLGTGGAGLTAALTAAVNGASVAVYEKAATIG
MMAR_4780|M.marinum_M --------MLWSQTFDVVVLGSGGAGLTAALSAAVAGATVAVFEKAPTVG
MUL_0349|M.ulcerans_Agy99 ---------MWSQTFDVVVLGSGGAGLTAALSAAVAGATVAVFEKAPTVG
MAV_0875|M.avium_104 --------MSWDHEVDVVVLGSGGAGLTAALTAAVAGASVQVYEKAPTVG
MLBr_01226|M.leprae_Br4923 ----MMAVPDWKHAADVVVIGTGVAGLAAALAAHRAGRNVVVLTKADQRR
**:*:*:* **:.*** * * . : **
Mb3567|M.bovis_AF2122/97 GSTARSGGGVWIPNNEVLKRRGVRDTPEAARTYLHGIVGEIVEPERIDAY
Rv3537|M.tuberculosis_H37Rv GSTARSGGGVWIPNNEVLKRRGVRDTPEAARTYLHGIVGEIVEPERIDAY
MAB_0622c|M.abscessus_ATCC_199 GSTARSGGGVWIPNNEVLKKARQTDTPEAAREYLYSIIGDVVPREKIDTY
Mflv_2398|M.gilvum_PYR-GCK GTTAVSGGIVWIPAHDR---AEGELTADDAMAYLRAQSLGFMDEDLVETF
Mvan_4248|M.vanbaalenii_PYR-1 GTTAVSGGIVWIPAHPRS--GDGELTAEDAMAYLRAQSLGYMDDELVETF
TH_4085|M.thermoresistible__bu GTTAVSGGIAWIPAHDR---ASDELTVEDAMAYLRAQSLGYMDDDLVETF
MSMEG_4870|M.smegmatis_MC2_155 GTTAVSGGIVWIPAHDR---AGEPLPVEDALAYLAAQSLGYMDTALVETF
MMAR_4780|M.marinum_M GTTAVSGGIAWIPAHQRS--PDRDLTVDDALRYLRAQSLHSMDDALVETF
MUL_0349|M.ulcerans_Agy99 GTTAVSGGIAWIPAHQRS--PDRDLTVDDALRYLRTQSLHSMDDALVETF
MAV_0875|M.avium_104 GTTAVSGGIVWIPAHNRC--PDGELTAADALKYLRAQSLGSMDDELVETF
MLBr_01226|M.leprae_Br4923 GETATHYAQGGIAVVLP----GSDDSVDAHASDTLAAGAGMCNLDTVYSI
* ** . *. . : :
Mb3567|M.bovis_AF2122/97 LDRGPEMLSFVLKHTPLKMCWVPGYSDYYPEAPGGRP-GGRSIEPKPFNA
Rv3537|M.tuberculosis_H37Rv LDRGPEMLSFVLKHTPLKMCWVPGYSDYYPEAPGGRP-GGRSIEPKPFNA
MAB_0622c|M.abscessus_ATCC_199 LDRGPEMLSFVLANSPLKLDWVPNYSDYYPEAPGGRA-AGRSVEPKPFDA
Mflv_2398|M.gilvum_PYR-GCK VRTGARMLDFVEQHSDLVFEVAAGFPDYKPELPGGKPAGGRSLNAKPFDL
Mvan_4248|M.vanbaalenii_PYR-1 VQSGAPMLDFLEAHSDLVFEVAAGFPDYKPELPGGKPGGGRSLHAGPFDL
TH_4085|M.thermoresistible__bu VRTGPQMLDFVERHSELRFEVAEGFPDYKPELPGGRPGGGRSLHAAPYDL
MSMEG_4870|M.smegmatis_MC2_155 VRTGPVMLDFVEAHSELRFAVAEGFPDYKPELPGGRPGGGRSLSAGPIDL
MMAR_4780|M.marinum_M VRTGAAMLDFVEKHSGVRFEIAAGFPDYRPELPGGQPAGGRSLGPAAFEP
MUL_0349|M.ulcerans_Agy99 VRTGAAMLDFVEKHSGVRFEIAAGFPDYRPELPGGQPAGGRSLGPAAFEP
MAV_0875|M.avium_104 VRTGPAMLDFIEAHSGLHFEIATGFPDYRPELPGGRPSGGRSLSAVPFDL
MLBr_01226|M.leprae_Br4923 VAEGYHAVTELVGYG-------ARFDESIPGRWAVTCEGGHSRRRIVHAG
: * : : : : * . .*:*
Mb3567|M.bovis_AF2122/97 RKLGADMAGLEPAYGKVPLNVVVMQQDYVRLNQLKRHPRGVLRSMKVGAR
Rv3537|M.tuberculosis_H37Rv RKLGADMAGLEPAYGKVPLNVVVMQQDYVRLNQLKRHPRGVLRSMKVGAR
MAB_0622c|M.abscessus_ATCC_199 KKLGDELPNLEPPYGKVPLNVVVRQQDYVRLNQLKRHPRGVLRSLRVGVR
Mflv_2398|M.gilvum_PYR-GCK SLLG-DWGERISSFPADFSNVGIDAETRARIHAAVD-E------------
Mvan_4248|M.vanbaalenii_PYR-1 ARLG-DWRDRITSFPADFSNVGIDAETRARIHAAVDNE------------
TH_4085|M.thermoresistible__bu GRLG-GWREKITSFPPDFSNVGIDAETRARIHAAVEDT------------
MSMEG_4870|M.smegmatis_MC2_155 ARLG-EWRDRITSFPADFSNVGIDAETRARIHAAYDDP------------
MMAR_4780|M.marinum_M SRLG-EWASRITSFPPDWSNVGFDAETRARLHAGVEE-------------
MUL_0349|M.ulcerans_Agy99 SRLG-EWASRITSFPPDWSNVGFDAETRARLHAGVEE-------------
MAV_0875|M.avium_104 ARLG-EWATRITSFPADWSNVGFDAETRARLHAAIDER------------
MLBr_01226|M.leprae_Br4923 GDATGAEVQRALDHAADVLDIRTSHLALRVLHDGTVVN------------
. :: ::
Mb3567|M.bovis_AF2122/97 TMWAKATGKNLVGMGRALIGPLRIGLQRAGVPVELNTAFTDLFVENGVVS
Rv3537|M.tuberculosis_H37Rv TMWAKATGKNLVGMGRALIGPLRIGLQRAGVPVELNTAFTDLFVENGVVS
MAB_0622c|M.abscessus_ATCC_199 TFWAQGTGKKLVGMGRALSAALRIGLRDAGVPVKLNTALTDLYIEDGTVR
Mflv_2398|M.gilvum_PYR-GCK -------AGDYCVAGTALIAGLLKGLLDRGVVPHTQARAVELTADPLGIT
Mvan_4248|M.vanbaalenii_PYR-1 -------SGDYCVAGTALIAGLLRSLLDRGITPHTEARAVELIADPLGIT
TH_4085|M.thermoresistible__bu -------DGDYCVAGTALIAGLLDALLRAGVAPHTNARALELIGDAGRIR
MSMEG_4870|M.smegmatis_MC2_155 -------DADLCVAGTALVAGLLRGLLDRGVKPVTSARAVELLGSADGIT
MMAR_4780|M.marinum_M -------SEDLCVAGTALVAGLLQGLLDVGVTPRTDAAAEELVVEDGAVV
MUL_0349|M.ulcerans_Agy99 -------SEDLCVAGTALVAGLLQGLLDVGVTPRTDAAAEELVVEDGAVV
MAV_0875|M.avium_104 -------TGHLCVAGTALIAGLLKGLLDLGVTPRVNARAEELVAEDGEIT
MLBr_01226|M.leprae_Br4923 --------------GVSVLNPNGWGIVSAPSVILASGGLGHLYGATTNPE
* :: .: . .*
Mb3567|M.bovis_AF2122/97 GVYVRDSHEAESAEPQLIRARRGVILACGGFEHNEQMRIKYQRAPITTEW
Rv3537|M.tuberculosis_H37Rv GVYVRDSHEAESAEPQLIRARRGVILACGGFEHNEQMRIKYQRAPITTEW
MAB_0622c|M.abscessus_ATCC_199 GVYVRETGAPEASEPTLIRGRRGVILASGGFEHNEQMRVKYQRAPITTEW
Mflv_2398|M.gilvum_PYR-GCK GVRIEQGSN-----DFRVRARKAVILGTGGFEWDQRLVEAYLRGPMRG--
Mvan_4248|M.vanbaalenii_PYR-1 GVRIEQGDS-----DFRVRAHRGVVLGTGGFEWDQRLVEAYLRGPMRG--
TH_4085|M.thermoresistible__bu GVRISRGDSGV-DQEMLVGARRGVVLATGGFEWDSRLVEAYLRGPMRG--
MSMEG_4870|M.smegmatis_MC2_155 GVRIRLDGT-----DIRVRARGGVVLATGGFEWDTTLVEAFLRGPMHG--
MMAR_4780|M.marinum_M GVRIAQSGR-----SISVRARRGVVLATGGFEWDPVLVRAFLRGPMHG--
MUL_0349|M.ulcerans_Agy99 GVRIAQSGR-----SISVRARRGVVLATGGFEWDPVLVRAFLRGPMHG--
MAV_0875|M.avium_104 GVRIASAEG-----RIGVRARRGVILGTGGFEWDPVLVQAFLRGPMHG--
MLBr_01226|M.leprae_Br4923 GS---TGDG------IALALWAGVAVSDLEFIQFHPTMLFAAGTGTGGRR
* : .* :. *
Mb3567|M.bovis_AF2122/97 TVGASANTGDGILAAEKLGAALDL-MDDAWWGPTVPLVG-------KPWF
Rv3537|M.tuberculosis_H37Rv TVGASANTGDGILAAEKLGAALDL-MDDAWWGPTVPLVG-------KPWF
MAB_0622c|M.abscessus_ATCC_199 TVGAKANTGDGILAAEKLGAALEF-MEDSWWGPTVPLVG-------RPWF
Mflv_2398|M.gilvum_PYR-GCK AVSPPNNTGDGLRMAMAHGADLAN-MGEAWWVPIVQIPGDTFEGRPRSRS
Mvan_4248|M.vanbaalenii_PYR-1 AVSPPNNTGDGLRMAMAHGADLAN-MGEAWWVPIVQIPGDTFEGQPRSRS
TH_4085|M.thermoresistible__bu AVSPPNNTGDGLRMAMAHGADLAN-MGEAWWVPIVQIPGDTFGGQPRSRS
MSMEG_4870|M.smegmatis_MC2_155 PVSPPNNTGDGLRMAMAHGADLAN-MGEAWWVPVVQIPGDTIDGHPRSRS
MMAR_4780|M.marinum_M AVSPPNNTGDGLRMAMARGAELAN-MGEAWWVPIVQIPNDTIDGKQRSRS
MUL_0349|M.ulcerans_Agy99 AVSPPNNTGDGLRMAMARGAELAN-MGEAWWVPIVQIPNDTIDGKQRSRS
MAV_0875|M.avium_104 AVSPPNNTGDGLRMAMAHGADLAN-MGEAWWVPIVQIPGDTIDGKPRSRS
MLBr_01226|M.leprae_Br4923 PLVTEAIRGEGAILLDSKGNSVTSGVHPLGDLAPRDVVAAAIDARLKATG
.: . *:* * : : . : :.
Mb3567|M.bovis_AF2122/97 ALSERNSPGSIIVNMSGKRFMNESMPYVEACHHMYGGEHGQGPGPG-ENI
Rv3537|M.tuberculosis_H37Rv ALSERNSPGSIIVNMSGKRFMNESMPYVEACHHMYGGEHGQGPGPG-ENI
MAB_0622c|M.abscessus_ATCC_199 ALSERNSPGSIIVNSSGKRFMNESLPYVEATHRMYGGQYGQGPGPG-ENL
Mflv_2398|M.gilvum_PYR-GCK VRLERTRPRSIIVNRAGRRFLNEAGEYNS----MAGPFHFLDPKLGYAND
Mvan_4248|M.vanbaalenii_PYR-1 VRLERTRPRSIIVNRAGRRFLNEAGEYNS----MAGPFHFLDPKLGYAND
TH_4085|M.thermoresistible__bu VRLERTRPRSIIVNRFGRRFVNEAGEYNS----MAGAFQYLDPRDGYVND
MSMEG_4870|M.smegmatis_MC2_155 IRLERTRPRSVIVNRAGNRFVNEAGEYNS----MAGPFQYLDPKAGYAND
MMAR_4780|M.marinum_M VRLERTRPRSIIVNPAGQRFVNEACDYNS----MAGAFHYLDPRGGYVND
MUL_0349|M.ulcerans_Agy99 VRLERTRPRSIIVNPAGQRFVNEACNYNS----MAGAFHYLDPRGGYVND
MAV_0875|M.avium_104 VRLERTRPRSIIVNAAGRRFVNEACDYNS----MAGAFHYLDPRGGYVND
MLBr_01226|M.leprae_Br4923 DSCVYLDARGIDGFASRFPTVTAACRTVG----IDPAREPIPVVPGAHYS
. .: :. : : *
Mb3567|M.bovis_AF2122/97 PAWLVFDQRYRDRYIFAGLQPGQRIPSRWLDSGVIVQADTLAELAGKAGL
Rv3537|M.tuberculosis_H37Rv PAWLVFDQRYRDRYIFAGLQPGQRIPSRWLDSGVIVQADTLAELAGKAGL
MAB_0622c|M.abscessus_ATCC_199 PAWLVFDQEYRNRYIFAGLQPGQKIPSKWIESGVIVKADTIEELAKKANL
Mflv_2398|M.gilvum_PYR-GCK PAWIVFDSLHLKHYGFLGVDPDGPVPDWFCQS------RDLEELGEKTGI
Mvan_4248|M.vanbaalenii_PYR-1 PAWIVFDSIHLKHYGFLGVDPDGPVPEWFCQS------ADLEELGEKTGI
TH_4085|M.thermoresistible__bu PAWIVFDAGHLERYGFLGVAPGEPVPDWFNAS------DDLAELATRTGI
MSMEG_4870|M.smegmatis_MC2_155 PAWIVFDSVHLQRYGFLGVEPGGQAPDWFCES------ADLDELSARTGI
MMAR_4780|M.marinum_M HAWIVFDSAHLQRYGFLGIEPGQPVPDWFCES------TDLTELATKTGI
MUL_0349|M.ulcerans_Agy99 HAWIVFDSAHLQRYGFLGIEPGQPVPDWFCES------TDLTELATKTGI
MAV_0875|M.avium_104 RGWMVFDSVHLQRYGFLGVEPGQPVPDWFCES------ADLAELAAKTGI
MLBr_01226|M.leprae_Br4923 CGGIVTDAYGQT--ELAGLFAAGEVARTGMHG-----ANRLASNSLLEGL
. :* * : *: . . . : . . .:
Mb3567|M.bovis_AF2122/97 PADELTATVQRFNAFA---RSGVDEDYHRGESAYDRYYGD--PSNKPNPN
Rv3537|M.tuberculosis_H37Rv PADELTATVQRFNAFA---RSGVDEDYHRGESAYDRYYGD--PSNKPNPN
MAB_0622c|M.abscessus_ATCC_199 PVEELRATIERFNGFA---RSGVDEDFGRGKSAYDRYYGD--PTNKPNPN
Mflv_2398|M.gilvum_PYR-GCK DPAGLEATLSAWNTNV---AAEHDPDFGRGASAYDGYWGDTDAATTAGRT
Mvan_4248|M.vanbaalenii_PYR-1 DPVGLGATLAAWNSNV---TQEHDPDFGRGASAYDGYWGDTTATTTAGQT
TH_4085|M.thermoresistible__bu DPDGLQRTVDAWNKNV---ADGVDPDFGRGSSAYDGYWGDTGAPTPAART
MSMEG_4870|M.smegmatis_MC2_155 DAAGLAATLRRWNDNVGRDTDPVDPDFGRGASAYDGYWGDTSADTPARQT
MMAR_4780|M.marinum_M DADGLGRTIARWNHNV---ASGTDPDFGRGASAYDGYWGDDQATTLAGKT
MUL_0349|M.ulcerans_Agy99 DADGLGRTIARWNHNV---ASGTDPDFGRGASAYDGYWGDDQATTLAGKT
MAV_0875|M.avium_104 DADGLTRTVENWNRYV---AAGVDPDFGRGSSAYDGYWGDDSATTQAGKT
MLBr_01226|M.leprae_Br4923 VVGGRAGRAAAAHAAAAG--RAYVSKLEPVTHHALKRRELQRVMSRDAAV
: . . .
Mb3567|M.bovis_AF2122/97 LGEVGHPPYYGAKMVPGDLGTKGGIRTDVNGRALRDDGSIIDGLYAAGNV
Rv3537|M.tuberculosis_H37Rv LGEVGHPPYYGAKMVPGDLGTKGGIRTDVNGRALRDDGSIIDGLYAAGNV
MAB_0622c|M.abscessus_ATCC_199 LGALTKAPFYAAKMVPGDLGTKGGVRTDVKGRVLRDDNSVIEGLYAAGNV
Mflv_2398|M.gilvum_PYR-GCK LGPIDTAPYYAVPVSVGAMGTKGGPRTDRDGRVLHVNGTAITGLFAAGNA
Mvan_4248|M.vanbaalenii_PYR-1 LGPIDTAPYFAVPVSIGAMGTKGGPRTDRDGRVLHVSGTAITGLFAAGNA
TH_4085|M.thermoresistible__bu LGPLDAAPYFAVPVRIGAMGTKGGPRTDRDGRVLHVSGAPIVGLYAAGNA
MSMEG_4870|M.smegmatis_MC2_155 LGPLDTAPFYAVPVKVGAMGTKGGPRTDRDGRVLHVNGSPIPGLYAAGNA
MMAR_4780|M.marinum_M LGPIDSAPFYAVPIRVGAMGTKGGPRTDRDGRVRHVSGGSVPGLFAAGNA
MUL_0349|M.ulcerans_Agy99 LGPIDSAPFYAVPIRVGAMGTKGGPRTDRDGRVRHVSGRSVPGLFTAGNA
MAV_0875|M.avium_104 LGPIDTAPYYAVPVSIGAMGTKGGPRTDRDARVLHVGGEPIPGLFAAGNA
MLBr_01226|M.leprae_Br4923 MRNAAGLQRLSDTLAEAPIRHVTGRRDFEDVALTLTARAVAAAALARNES
: . : . : * * . . : .:
Mb3567|M.bovis_AF2122/97 SAPVMGHTYPGPGGTIGPAMTFGYLAALHIADQAGKR-------------
Rv3537|M.tuberculosis_H37Rv SAPVMGHTYPGPGGTIGPAMTFGYLAALHIADQAGKR-------------
MAB_0622c|M.abscessus_ATCC_199 STPVMGHTYAGPGATIGPAMTWGYLAALDIAGK-----------------
Mflv_2398|M.gilvum_PYR-GCK MAGATGKAYGGAGGTIGPAMVFGYRAGHAAATGTSLS-------------
Mvan_4248|M.vanbaalenii_PYR-1 MAGATGKAYGGAGGTLGPAMVFGYRAGYTAATGKSAP-------------
TH_4085|M.thermoresistible__bu MAGVTGKAYGGAGGTLGPALVFGFRAGHHAATGGSVDXXXRLTRCRWALP
MSMEG_4870|M.smegmatis_MC2_155 MAGVTGKAYGGAGGTLGPALVFGYRSGYAAATGKSVD-------------
MMAR_4780|M.marinum_M MAGVTGRAYGGAGGTIGPAMVFGYRAGRAAATGESADAP-----------
MUL_0349|M.ulcerans_Agy99 MAGVTGLAYGGAGGTIGPAMVFGYRAGRAVATGESADAP-----------
MAV_0875|M.avium_104 MGGVTGRAYGGAGGTLGPAMVFGYRAGHAAATGKSVDLQ-----------
MLBr_01226|M.leprae_Br4923 RGCHHCTEYPDTAPEHARSTVIRLADDQNLVRAEALATVG----------
* ... . : . .
Mb3567|M.bovis_AF2122/97 ----------------------------
Rv3537|M.tuberculosis_H37Rv ----------------------------
MAB_0622c|M.abscessus_ATCC_199 ----------------------------
Mflv_2398|M.gilvum_PYR-GCK ----------------------------
Mvan_4248|M.vanbaalenii_PYR-1 ----------------------------
TH_4085|M.thermoresistible__bu SASRASSPADVTPGSSVNGANGSVTKPR
MSMEG_4870|M.smegmatis_MC2_155 ----------------------------
MMAR_4780|M.marinum_M ----------------------------
MUL_0349|M.ulcerans_Agy99 ----------------------------
MAV_0875|M.avium_104 ----------------------------
MLBr_01226|M.leprae_Br4923 ----------------------------