For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4171 | - | - | 100% (295) | aldehyde dehydrogenase |
| M. thermoresistible (build 8) | TH_3591 | - | 5e-87 | 52.13% (282) | PUTATIVE putative Betaine-aldehyde dehydrogenase |
| M. thermoresistible (build 8) | TH_3068 | - | 1e-86 | 55.12% (283) | PUTATIVE aldehyde dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0791 | aldA | 4e-67 | 46.62% (281) | aldehyde dehydrogenase NAD dependant AldA |
| M. gilvum PYR-GCK | Mflv_0428 | - | 1e-144 | 84.59% (292) | betaine-aldehyde dehydrogenase |
| M. tuberculosis H37Rv | Rv0223c | - | 1e-134 | 79.04% (291) | aldehyde dehydrogenase |
| M. leprae Br4923 | MLBr_02573 | gabD1 | 8e-48 | 36.49% (285) | succinic semialdehyde dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4484 | - | 1e-128 | 75.77% (293) | aldehyde dehydrogenase |
| M. marinum M | MMAR_0472 | - | 1e-133 | 77.82% (293) | aldehyde dehydrogenase |
| M. avium 104 | MAV_4946 | - | 1e-132 | 77.74% (292) | aldehyde dehydrogenase family protein |
| M. smegmatis MC2 155 | MSMEG_0309 | - | 1e-149 | 88.01% (292) | aldehyde dehydrogenase family protein |
| M. ulcerans Agy99 | MUL_1122 | - | 1e-131 | 76.79% (293) | aldehyde dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0240 | - | 1e-143 | 84.93% (292) | betaine-aldehyde dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
TH_4171|M.thermoresistible__bu --------------------------------------------------
MSMEG_0309|M.smegmatis_MC2_155 MTAMTQTAPAATAATTNWDKLFIGGQWVEPSSSEIIEVFSPATGEKVGQA
Mflv_0428|M.gilvum_PYR-GCK ---MTQS----TAFRTEWDKLFIGGKWVEPASSEVIEVRSPATGDVVGKV
Mvan_0240|M.vanbaalenii_PYR-1 ---MTQS----TTFRTEWDKLFIGGKWVEPATSDVIEVHSPATGELVGKV
MMAR_0472|M.marinum_M -----------MGEKTEYDKLFIGGKWTEPSTSEVIEVHCPATGEYVGKV
MUL_1122|M.ulcerans_Agy99 -----------MGEKTEYDKLFIGGRWTEPSTSEVIEVHCPATGEYVGKV
MAV_4946|M.avium_104 ------MSDIQTQAKTEYDKLFIGGKWTEPSTSEVIEVHCPATGEYVGKV
Rv0223c|M.tuberculosis_H37Rv ----------MSDSATEYDKLFIGGKWTKPSTSDVIEVRCPATGEYVGKV
MAB_4484|M.abscessus_ATCC_1997 --------------MTNYDKLFIGGVWTEPATDQVIEVISPATGQKVGQC
Mb0791|M.bovis_AF2122/97 ----------MALWGDGISALLIDGKLSD-GRAGTFPTVNPATEEVLGVA
MLBr_02573|M.leprae_Br4923 ---------------------------------MSIATINPATGETVKTF
TH_4171|M.thermoresistible__bu --------------------------------------------------
MSMEG_0309|M.smegmatis_MC2_155 PLATKADVDAACAAARKAFDEGPWPRMTPQEREAVLAKATALIEESADEF
Mflv_0428|M.gilvum_PYR-GCK PLASAADVDAACAAAREAFDNGPWPQMSPTERAEVLGRAVKLMEERADEL
Mvan_0240|M.vanbaalenii_PYR-1 PLASAADVDAACAAAREAFDNGPWPHMSPAERGEILGRAVKIMEERADEL
MMAR_0472|M.marinum_M PLAAAADVDAAVAAARAAFDNGPWPSTPPKERATVIANALKLLEERKDHF
MUL_1122|M.ulcerans_Agy99 PLAAAADVDAAVAAARAAFDNGPWPSTPPKERATVIANALKLLEERKDHF
MAV_4946|M.avium_104 PLAAAADVDAAVAAARAAFDNGPWPTTPPKERAAVIANALKVMEERKDLF
Rv0223c|M.tuberculosis_H37Rv PMAAAADVDAAVAAARAAFDNGPWPSTPPHERAAVIAAAVKMLAERKDLF
MAB_4484|M.abscessus_ATCC_1997 PLASPADVDAAVSAARRAFDNGPWPRLTPHERQAVLQKAVSLLESRKDEI
Mb0791|M.bovis_AF2122/97 ADADAEDMGRAIEAARRAFDSTDWSRN-TELRVRCVRQLRDAMQQHVEEL
MLBr_02573|M.leprae_Br4923 TPTTQDEVEDAIARAYARFDN--YRHTTFTQRAKWANATADLLEAEANQS
TH_4171|M.thermoresistible__bu --------------------------------------------------
MSMEG_0309|M.smegmatis_MC2_155 KTLLKLETGQPQTIVDMMQYGAAMSTLQFYAS-AADKFAWKDIR-----D
Mflv_0428|M.gilvum_PYR-GCK KFLLAAETGQPPTIVDMMQYGAAMSSFQFYAG-AADKFTWQDIR-----D
Mvan_0240|M.vanbaalenii_PYR-1 KFLLAAETGQPPTIVDMMQYGAAMSSFQFYAG-AADKFTWQDIR-----D
MMAR_0472|M.marinum_M AKLLADETGQPPMTVETMHWMGSIGALNFFAGPAVDQVRWKEIR-----N
MUL_1122|M.ulcerans_Agy99 AKLFADETGQPPMTVETMHWMGSIGALNFFAGPAVDQVRWKEIR-----N
MAV_4946|M.avium_104 TGLLAAETGQPPTSVETMHWMSSIGALNFFAGPAVDQVKWKEVR-----T
Rv0223c|M.tuberculosis_H37Rv TKLLAAETGQPPTIIETMHWMGSMGAMNYFAG-AADKVTWTETR-----T
MAB_4484|M.abscessus_ATCC_1997 CKAIADETGAPPMVIETLQWMGGFGAIQYYAN-AADAVKWKELR-----N
Mb0791|M.bovis_AF2122/97 RELTISEVGAPRMLTASAQLEGPVGDLSFAAD-TAESYPWKQDLGEASPL
MLBr_02573|M.leprae_Br4923 AALMTLEMGKTLQSAKDEAMKCAKG-FRYYAEKAETLLADEPAEA---AA
TH_4171|M.thermoresistible__bu --------------------------------------------------
MSMEG_0309|M.smegmatis_MC2_155 GIYGQTLVLKEPVGVVGAVVAWNVPFFLAANKLGPALLAGCTIVLKPAAE
Mflv_0428|M.gilvum_PYR-GCK GVYGQTLVVREPVGVVGAVTAWNVPFFLAANKLGPALLAGCTVVLKPAAE
Mvan_0240|M.vanbaalenii_PYR-1 GVYGQTLVVREPVGVVGAVTAWNVPFFLAANKLGPALLAGCTVVLKPAAE
MMAR_0472|M.marinum_M GSYGQTIVHREPIGVVGAIVAWNVPLFLAINKLGPALLAGCTVVLKPAAE
MUL_1122|M.ulcerans_Agy99 GSYGQTIVHREPIGVVGAIVAWNVPLFLAINKLGPAPLAGCTVVLKPAAE
MAV_4946|M.avium_104 GGYGQSIVHREPIGVVGAIVAWNVPLFLAVNKLGPALLAGCTVVLKPAAE
Rv0223c|M.tuberculosis_H37Rv GSYGQSIVSREPVGVVGAIVAWNVPLFLAVNKIAPALLAGCTIVLKPAAE
MAB_4484|M.abscessus_ATCC_1997 GAYGQTLVTREPAGVVAAIAAWNVPLFLALNKIGPAFLAGCAVVLKPAAE
Mb0791|M.bovis_AF2122/97 GIATRRTLAREAVGVVGAITPWNFPHQINLAKLGPALAAGNTVVLKPAPD
MLBr_02573|M.leprae_Br4923 VGASKALARYQPLGVVLAVMPWNFPLWQTVRFAAPALMAGNVGLLKHASN
TH_4171|M.thermoresistible__bu ----------VFAEAG-LPEGVLSVVPGG-AETGRALTSNKDLDKYTFTG
MSMEG_0309|M.smegmatis_MC2_155 TPLTTNLMAQKFLEAG-LPEGVLSVVPGG-PETGRALTDNPALDKFTFTG
Mflv_0428|M.gilvum_PYR-GCK TPLSVFAMAEMFVEAG-LPEGVLSIVPGG-PETGQALTANPNLDKYTFTG
Mvan_0240|M.vanbaalenii_PYR-1 TPLSVFAMAEMFVEAG-LPEGVLSIVPGG-PETGQALTANPNLDKYTFTG
MMAR_0472|M.marinum_M TPLTANALAEVFAEAG-LPEGVLSVVPGG-VETGQALTSNPGVDLFTFTG
MUL_1122|M.ulcerans_Agy99 TPLTANALAEVFAEAG-LPEGVLSVVPGG-VETGQALTSNPGVDLFTFTG
MAV_4946|M.avium_104 TPLSANALAEAFAEAG-LPEGVLSVVPGG-IETGQALTSNTDVDIFSFTG
Rv0223c|M.tuberculosis_H37Rv TPLTANALAEVFAEVG-LPEGVLSVVPGG-IETGQALTSNPDIDMFTFTG
MAB_4484|M.abscessus_ATCC_1997 TPLSSFILAEVFAEAG-VPEGVLSVVPGG-AETGRALTNNPDVDVFSFTG
Mb0791|M.bovis_AF2122/97 TPWCAAALGEIIVEHTDFPPGVVNIVTSSSHALGALLAKDPRVDMISFTG
MLBr_02573|M.leprae_Br4923 VPQCALYLADVIARGG-FPEDCFQTLLIS-ANGVEAILRDPRVAAATLTG
: . .* . .. : . : : : ::**
TH_4171|M.thermoresistible__bu SSAVGREIGKIAAENLKPCTLELGGKSAAIILEDADLDATLPMLVFSGVM
MSMEG_0309|M.smegmatis_MC2_155 SSAVGKEIGKIAAEKLKPCTLELGGKSAAIILEDADLDSTLPMLLFSGLM
Mflv_0428|M.gilvum_PYR-GCK SSGVGKEIAKIAADKLKPCTLELGGKSAAIILEDADLDSTLPMLVFSGLM
Mvan_0240|M.vanbaalenii_PYR-1 SSGVGKEIAKIAADKLKPCTLELGGKSAAIILEDADLDSTLPMLVFSGLM
MMAR_0472|M.marinum_M SSAVGKEIGRRAAEMLKPCTLELGGKSAAILLEDVDLSTAVPMMVFSGIM
MUL_1122|M.ulcerans_Agy99 SSAVGKEIGRRAAEMLKPCTLELGGKSAAILLEDVDLSTAVPMMVFSGIM
MAV_4946|M.avium_104 SSAVGREIGRRAADMLKPCTLELGGKSAAIVLDDVDLPSALPMLVFSGIM
Rv0223c|M.tuberculosis_H37Rv SSAVGREVGRRAAEMLKPCTLELGGKSAAIILEDVDLAAAIPMMVFSGVM
MAB_4484|M.abscessus_ATCC_1997 STAVGKEIAEIAAKNLKKVTLELGGKSAAIVLEDADLAAALPMLVFSGLM
Mb0791|M.bovis_AF2122/97 STATGRAVMADAAATIKKVFLELGGKSAFVVLDDADLAAASAVSAFSACM
MLBr_02573|M.leprae_Br4923 SEPAGQAVGAIAGNEIKPTVLELGGSDPFIVMPSADLDAAVATAVTGRVQ
* .*: : *. :* *****... ::: ..** :: . .
TH_4171|M.thermoresistible__bu NSGQACVGQTRILAPRSRYDEVVEKVANFVAAMPVGLPDDPNTAIGPLIS
MSMEG_0309|M.smegmatis_MC2_155 NSGQACVGQTRILAPRSRYDEVVEKVAAGVAAMQVGVPDDPAAMVGPLIS
Mflv_0428|M.gilvum_PYR-GCK NSGQACVGQTRILAPRSRYDEVIEKLGEAVRNMAPGLPDNPAAMIGPLIS
Mvan_0240|M.vanbaalenii_PYR-1 NSGQACVGQTRILAPRSRYDEVVEKLAAAAAGMAPGLPDNPAAMIGPLIS
MMAR_0472|M.marinum_M NTGQACVGQTRILAPRSRYEEIVEAVSAFVQALPVGPPSDPAAQIGSLIS
MUL_1122|M.ulcerans_Agy99 NTGQACVGQTRILAPRSRYEEIVEAVSAFVQTLPVGPPSDPAAQIGSLIS
MAV_4946|M.avium_104 NSGQACVAQTRILAPRSRYDEIVDAVSTFVQSLPVGLPSDPAAQIGSLIS
Rv0223c|M.tuberculosis_H37Rv NAGQGCVNQTRILAPRSRYDEIVAAVTNFVTALPVGPPSDPAAQIGPLIS
MAB_4484|M.abscessus_ATCC_1997 NAGQGCVNQTRVLAPRSRYDEVVDGIVGMVSLMGVGLPDDPATQVGPLIT
Mb0791|M.bovis_AF2122/97 HAGQGCAITTRLVVPRARYEEAVAIAAATMSSIRPGDPNDPGTVCGPLIS
MLBr_02573|M.leprae_Br4923 NNGQSCIAAKRFIAHADIYDEFVEKFVARMETLRVGDPTDPDTDVGPLAT
: **.* .*.:. *:* : : * * :* : *.* :
TH_4171|M.thermoresistible__bu EKQRERVEGYIKKGIEEGARLVTGGGRPEGLDSGWFVQPTVFADVDNSMT
MSMEG_0309|M.smegmatis_MC2_155 EKQRERVEGYIKKGIEEGARLVTGGGRPEGLDSGWFVQPTVFADVDNSMT
Mflv_0428|M.gilvum_PYR-GCK EKQRDRVEGYIKKGIEEGARVITGGGRPEGLDSGWFVEPTVFADVDNSMT
Mvan_0240|M.vanbaalenii_PYR-1 EKQRDRVEGYIKKGIEEGARVVTGGGRPEGLDSGWYVQPTVFADVDNSMT
MMAR_0472|M.marinum_M EKQRARVEGYIAKGIEEGARLVSGGGRPEGLDNGFFVQPTVFADVDNKMT
MUL_1122|M.ulcerans_Agy99 EKQRARVEGYIAKGIEEGARLVSGGGRPESLDNGFFVQPTVFADVDNKMT
MAV_4946|M.avium_104 EKQRARVEGYIAKGIEEGARLVCGGGRPEGLDSGFFVQPTVFADVDNKMT
Rv0223c|M.tuberculosis_H37Rv EKQRTRVEGYIAKGIEEGARLVCGGGRPEGLDNGFFIQPTVFADVDNKMT
MAB_4484|M.abscessus_ATCC_1997 EKQRTRVEGYIAKGIAEGARLAYGGKRPEGLDGGYFVQPTIFADVDNSMT
Mb0791|M.bovis_AF2122/97 ARQRDRVQGYLDLAVAEGGRFACGGARPADREVGFYIEPTVIAGLTNDAR
MLBr_02573|M.leprae_Br4923 ESGRAQVEQQVDAAAAAGAVIRCGGKRPD--RPGWFYPPTVITDITKDMA
* :*: : . *. . ** ** *:: **:::.: :.
TH_4171|M.thermoresistible__bu IAQEEIFGPVLCIIPYEDEDDAVRIANDSVYGLAGSVYTQDYPKALEIAS
MSMEG_0309|M.smegmatis_MC2_155 IAQEEIFGPVLVVIPFEDEDDAVRIANDSVYGLAGSVYTTDHAKGVEIAS
Mflv_0428|M.gilvum_PYR-GCK IAQEEIFGPVLSVIPYEDEDDAVRIANDSVYGLAGSVYTTDNDRALKIAR
Mvan_0240|M.vanbaalenii_PYR-1 IAQEEIFGPVLAVIPYEDEDDAVRIANDSVYGLAGSVYTTDNDRALKIAR
MMAR_0472|M.marinum_M IAQEEIFGPVLVVIPYDTEEDAIKIANDSVYGLAGSVWTSNVPKGIEISE
MUL_1122|M.ulcerans_Agy99 IAQEEIFGPVLVVIPYDTKEDAIKIANDSVYGLAGSVWTSNVPKGIEISE
MAV_4946|M.avium_104 IAQEEIFGPVLSIIPYDTEEDAIKIANDSVYGLAGSVWTADVQRGIAVSE
Rv0223c|M.tuberculosis_H37Rv IAQEEIFGPVLAIIPYDTEEDAIAIANDSVYGLAGSVWTTDVPKGIKISQ
MAB_4484|M.abscessus_ATCC_1997 IAQEEIFGPVLSIIAYDSVDEAVKIANDSNYGLAGSVWTTDVQKGLEVAA
Mb0791|M.bovis_AF2122/97 VAREEIFGPVLTVIAHDGDDDAVRIANDSPYGLSGTVYGADPQRAARIAS
MLBr_02573|M.leprae_Br4923 LYTDEVFGPVASVYCATNIDDAIEIANATPFGLGSNAWTQNESEQRHFID
: :*:**** : ::*: *** : :**....: : . .
TH_4171|M.thermoresistible__bu KIRTGTYAVN---MYAFDPGAPFGGYKNSGIGRENGPEGIEAYCQQKSVL
MSMEG_0309|M.smegmatis_MC2_155 KVRTGTYGIN---MYAFDPGAPFGGYKNSGIGRECGPEGIAGYCESKSVL
Mflv_0428|M.gilvum_PYR-GCK RIRTGTYAVN---MYAFDPCAPFGGYKNSGIGRENGWEGIEAYCEQKSIL
Mvan_0240|M.vanbaalenii_PYR-1 RIRTGTYAVN---MYAFDPCAPFGGFKNSGIGRENGWEGIEAYCEPKSIL
MMAR_0472|M.marinum_M KIRTGTYAIN---WYAFDPCCPFGGYKNSGIGRENGPEGVEHFTQQKSVL
MUL_1122|M.ulcerans_Agy99 KIRTGTYAIN---WYAFDPCCPFGGYKNSGIGRENGPEGVEHFTQQKSVL
MAV_4946|M.avium_104 KIRTGTYAIN---WYAFDPCCPFGGYKNSGIGRENGPEGVEHFTQQKSVL
Rv0223c|M.tuberculosis_H37Rv QIRTGTYGIN---WYAFDPGSPFGGYKNSGIGRENGPEGVEHFTQQKSVL
MAB_4484|M.abscessus_ATCC_1997 QIRTGTYGIN---WYAFDPSCPFGGYKQSGIGRENGPEGIEEYCELKSVL
Mb0791|M.bovis_AF2122/97 RLRVGTVNVNGGVWYCAD--APFGGYKQSGIGREMGLLGFEEYLEAKLIA
MLBr_02573|M.leprae_Br4923 NIVAGQVFING--MTVSYPELPFGGIKRSGYGRELSTHGIREFCNIKTVW
.: .* :* **** *.** *** . *. : : * :
TH_4171|M.thermoresistible__bu LPFGYTPED-
MSMEG_0309|M.smegmatis_MC2_155 LPFGYTPE--
Mflv_0428|M.gilvum_PYR-GCK LPFGYTPPAS
Mvan_0240|M.vanbaalenii_PYR-1 LPFGYTPAT-
MMAR_0472|M.marinum_M MPMGYTLES-
MUL_1122|M.ulcerans_Agy99 MPMGYTLES-
MAV_4946|M.avium_104 MPMGYTLEG-
Rv0223c|M.tuberculosis_H37Rv LPMGYTVA--
MAB_4484|M.abscessus_ATCC_1997 LPMGYTLESI
Mb0791|M.bovis_AF2122/97 TAAN------
MLBr_02573|M.leprae_Br4923 IA--------
.