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M. thermoresistible (build 8) TH_3591 (-)

annotation: putative Betaine-aldehyde dehydrogenase
coordinates: 4585974 - 4587530
length: 519

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3591--100% (519)putative Betaine-aldehyde dehydrogenase
M. thermoresistible (build 8)TH_4112-e-18072.73% (407) PUTATIVE putative putative acetyl-/propionyl-coenzyme A
M. thermoresistible (build 8)TH_3068-e-11446.25% (480) PUTATIVE aldehyde dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0791aldA6e-9440.77% (493) aldehyde dehydrogenase NAD dependant AldA
M. gilvum PYR-GCKMflv_0428-1e-12547.24% (489) betaine-aldehyde dehydrogenase
M. tuberculosis H37RvRv0223c-1e-11944.18% (498) aldehyde dehydrogenase
M. leprae Br4923MLBr_02573gabD14e-5629.45% (472) succinic semialdehyde dehydrogenase
M. abscessus ATCC 19977MAB_4484-1e-11744.06% (488) aldehyde dehydrogenase
M. marinum MMMAR_0472-1e-11544.58% (489) aldehyde dehydrogenase
M. avium 104MAV_4946-1e-11645.19% (489) aldehyde dehydrogenase family protein
M. smegmatis MC2 155MSMEG_0309-1e-12144.88% (488) aldehyde dehydrogenase family protein
M. ulcerans Agy99MUL_1122-1e-11344.17% (489) aldehyde dehydrogenase
M. vanbaalenii PYR-1Mvan_0240-1e-12547.65% (489) betaine-aldehyde dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_0472|M.marinum_M               -----------MGEKTEYDKLFIGGKWTEPSTSEVIEVHCPATGEYVGKV
MUL_1122|M.ulcerans_Agy99           -----------MGEKTEYDKLFIGGRWTEPSTSEVIEVHCPATGEYVGKV
MAV_4946|M.avium_104                ------MSDIQTQAKTEYDKLFIGGKWTEPSTSEVIEVHCPATGEYVGKV
Rv0223c|M.tuberculosis_H37Rv        ----------MSDSATEYDKLFIGGKWTKPSTSDVIEVRCPATGEYVGKV
MAB_4484|M.abscessus_ATCC_1997      --------------MTNYDKLFIGGVWTEPATDQVIEVISPATGQKVGQC
Mflv_0428|M.gilvum_PYR-GCK          ---MTQS----TAFRTEWDKLFIGGKWVEPASSEVIEVRSPATGDVVGKV
Mvan_0240|M.vanbaalenii_PYR-1       ---MTQS----TTFRTEWDKLFIGGKWVEPATSDVIEVHSPATGELVGKV
MSMEG_0309|M.smegmatis_MC2_155      MTAMTQTAPAATAATTNWDKLFIGGQWVEPSSSEIIEVFSPATGEKVGQA
TH_3591|M.thermoresistible__bu      ------------MLARTYSSFFIDGDWREPASTETFTVISPASGEPIGSV
Mb0791|M.bovis_AF2122/97            ----------MALWGDGISALLIDGKLSD-GRAGTFPTVNPATEEVLGVA
MLBr_02573|M.leprae_Br4923          ---------------------------------MSIATINPATGETVKTF
                                                                       : .  **: : :   

MMAR_0472|M.marinum_M               PLAAAADVDAAVAAARAAFDNGPWPSTPPKERATVIANALKLLEERKDHF
MUL_1122|M.ulcerans_Agy99           PLAAAADVDAAVAAARAAFDNGPWPSTPPKERATVIANALKLLEERKDHF
MAV_4946|M.avium_104                PLAAAADVDAAVAAARAAFDNGPWPTTPPKERAAVIANALKVMEERKDLF
Rv0223c|M.tuberculosis_H37Rv        PMAAAADVDAAVAAARAAFDNGPWPSTPPHERAAVIAAAVKMLAERKDLF
MAB_4484|M.abscessus_ATCC_1997      PLASPADVDAAVSAARRAFDNGPWPRLTPHERQAVLQKAVSLLESRKDEI
Mflv_0428|M.gilvum_PYR-GCK          PLASAADVDAACAAAREAFDNGPWPQMSPTERAEVLGRAVKLMEERADEL
Mvan_0240|M.vanbaalenii_PYR-1       PLASAADVDAACAAAREAFDNGPWPHMSPAERGEILGRAVKIMEERADEL
MSMEG_0309|M.smegmatis_MC2_155      PLATKADVDAACAAARKAFDEGPWPRMTPQEREAVLAKATALIEESADEF
TH_3591|M.thermoresistible__bu      PSASTADIDVAVEAARRAFYETDWPRRPVEERAALCEALAAKIHEHRADF
Mb0791|M.bovis_AF2122/97            ADADAEDMGRAIEAARRAFDSTDWSRN-TELRVRCVRQLRDAMQQHVEEL
MLBr_02573|M.leprae_Br4923          TPTTQDEVEDAIARAYARFDN--YRHTTFTQRAKWANATADLLEAEANQS
                                    . :   ::  *   *   * .  :       *          :       

MMAR_0472|M.marinum_M               AKLLADETGQPPMTVETMHWMGSIGALNFFAGPAVDQVRWKEIR--NGSY
MUL_1122|M.ulcerans_Agy99           AKLFADETGQPPMTVETMHWMGSIGALNFFAGPAVDQVRWKEIR--NGSY
MAV_4946|M.avium_104                TGLLAAETGQPPTSVETMHWMSSIGALNFFAGPAVDQVKWKEVR--TGGY
Rv0223c|M.tuberculosis_H37Rv        TKLLAAETGQPPTIIETMHWMGSMGAMNYFAG-AADKVTWTETR--TGSY
MAB_4484|M.abscessus_ATCC_1997      CKAIADETGAPPMVIETLQWMGGFGAIQYYAN-AADAVKWKELR--NGAY
Mflv_0428|M.gilvum_PYR-GCK          KFLLAAETGQPPTIVDMMQYGAAMSSFQFYAG-AADKFTWQDIR--DGVY
Mvan_0240|M.vanbaalenii_PYR-1       KFLLAAETGQPPTIVDMMQYGAAMSSFQFYAG-AADKFTWQDIR--DGVY
MSMEG_0309|M.smegmatis_MC2_155      KTLLKLETGQPQTIVDMMQYGAAMSTLQFYAS-AADKFAWKDIR--DGIY
TH_3591|M.thermoresistible__bu      IDLVVDELGCTRQLAEVYQAVAPTLHWNYNAE-VARNYPLSEVR--TADL
Mb0791|M.bovis_AF2122/97            RELTISEVGAPRMLTASAQLEGPVGDLSFAAD-TAESYPWKQDLGEASPL
MLBr_02573|M.leprae_Br4923          AALMTLEMGKTLQSAKDEAMKCAKG-FRYYAEKAETLLADEPAEAAAVGA
                                          * * .                 : *  .                

MMAR_0472|M.marinum_M               G----------------QTIVHREPIGVVGAIVAWNVPLFLAINKLGPAL
MUL_1122|M.ulcerans_Agy99           G----------------QTIVHREPIGVVGAIVAWNVPLFLAINKLGPAP
MAV_4946|M.avium_104                G----------------QSIVHREPIGVVGAIVAWNVPLFLAVNKLGPAL
Rv0223c|M.tuberculosis_H37Rv        G----------------QSIVSREPVGVVGAIVAWNVPLFLAVNKIAPAL
MAB_4484|M.abscessus_ATCC_1997      G----------------QTLVTREPAGVVAAIAAWNVPLFLALNKIGPAF
Mflv_0428|M.gilvum_PYR-GCK          G----------------QTLVVREPVGVVGAVTAWNVPFFLAANKLGPAL
Mvan_0240|M.vanbaalenii_PYR-1       G----------------QTLVVREPVGVVGAVTAWNVPFFLAANKLGPAL
MSMEG_0309|M.smegmatis_MC2_155      G----------------QTLVLKEPVGVVGAVVAWNVPFFLAANKLGPAL
TH_3591|M.thermoresistible__bu      GPLAGGSEGGMIMPYQTQSLVVREPVGVVATLVAYNFAFAGTAQKVAPAV
Mb0791|M.bovis_AF2122/97            G-------------IATRRTLAREAVGVVGAITPWNFPHQINLAKLGPAL
MLBr_02573|M.leprae_Br4923          S----------------KALARYQPLGVVLAVMPWNFPLWQTVRFAAPAL
                                    .                :     :. *** :: .:*..        .** 

MMAR_0472|M.marinum_M               LAGCTVVLKPAAETPLTANALAEVFAEAG-LPEGVLSVVPGG-VETGQAL
MUL_1122|M.ulcerans_Agy99           LAGCTVVLKPAAETPLTANALAEVFAEAG-LPEGVLSVVPGG-VETGQAL
MAV_4946|M.avium_104                LAGCTVVLKPAAETPLSANALAEAFAEAG-LPEGVLSVVPGG-IETGQAL
Rv0223c|M.tuberculosis_H37Rv        LAGCTIVLKPAAETPLTANALAEVFAEVG-LPEGVLSVVPGG-IETGQAL
MAB_4484|M.abscessus_ATCC_1997      LAGCAVVLKPAAETPLSSFILAEVFAEAG-VPEGVLSVVPGG-AETGRAL
Mflv_0428|M.gilvum_PYR-GCK          LAGCTVVLKPAAETPLSVFAMAEMFVEAG-LPEGVLSIVPGG-PETGQAL
Mvan_0240|M.vanbaalenii_PYR-1       LAGCTVVLKPAAETPLSVFAMAEMFVEAG-LPEGVLSIVPGG-PETGQAL
MSMEG_0309|M.smegmatis_MC2_155      LAGCTIVLKPAAETPLTTNLMAQKFLEAG-LPEGVLSVVPGG-PETGRAL
TH_3591|M.thermoresistible__bu      AAGCTVVIKVPEPNPLAIFAMGELIREVG-FPPGVINIVAAG-PAASEHL
Mb0791|M.bovis_AF2122/97            AAGNTVVLKPAPDTPWCAAALGEIIVEHTDFPPGVVNIVTSSSHALGALL
MLBr_02573|M.leprae_Br4923          MAGNVGLLKHASNVPQCALYLADVIARGG-FPEDCFQTLLIS-ANGVEAI
                                     ** . ::* .   *     :.: : .   .* . .. :  .       :

MMAR_0472|M.marinum_M               TSNPGVDLFTFTGSSAVGKEIGRRAAEMLKPCTLELGGKSAAILLEDVDL
MUL_1122|M.ulcerans_Agy99           TSNPGVDLFTFTGSSAVGKEIGRRAAEMLKPCTLELGGKSAAILLEDVDL
MAV_4946|M.avium_104                TSNTDVDIFSFTGSSAVGREIGRRAADMLKPCTLELGGKSAAIVLDDVDL
Rv0223c|M.tuberculosis_H37Rv        TSNPDIDMFTFTGSSAVGREVGRRAAEMLKPCTLELGGKSAAIILEDVDL
MAB_4484|M.abscessus_ATCC_1997      TNNPDVDVFSFTGSTAVGKEIAEIAAKNLKKVTLELGGKSAAIVLEDADL
Mflv_0428|M.gilvum_PYR-GCK          TANPNLDKYTFTGSSGVGKEIAKIAADKLKPCTLELGGKSAAIILEDADL
Mvan_0240|M.vanbaalenii_PYR-1       TANPNLDKYTFTGSSGVGKEIAKIAADKLKPCTLELGGKSAAIILEDADL
MSMEG_0309|M.smegmatis_MC2_155      TDNPALDKFTFTGSSAVGKEIGKIAAEKLKPCTLELGGKSAAIILEDADL
TH_3591|M.thermoresistible__bu      VSHPDVDMVSFTGSTTVGSKIGRVCGERIRPAVLELGGKSAAIVLDDADL
Mb0791|M.bovis_AF2122/97            AKDPRVDMISFTGSTATGRAVMADAAATIKKVFLELGGKSAFVVLDDADL
MLBr_02573|M.leprae_Br4923          LRDPRVAAATLTGSEPAGQAVGAIAGNEIKPTVLELGGSDPFIVMPSADL
                                      .. :   ::***  .*  :   ..  ::   *****... ::: ..**

MMAR_0472|M.marinum_M               STAVPMMV-FSGIMNTGQACVGQTRILAPRSRYEEIVEAVSAFVQALPVG
MUL_1122|M.ulcerans_Agy99           STAVPMMV-FSGIMNTGQACVGQTRILAPRSRYEEIVEAVSAFVQTLPVG
MAV_4946|M.avium_104                PSALPMLV-FSGIMNSGQACVAQTRILAPRSRYDEIVDAVSTFVQSLPVG
Rv0223c|M.tuberculosis_H37Rv        AAAIPMMV-FSGVMNAGQGCVNQTRILAPRSRYDEIVAAVTNFVTALPVG
MAB_4484|M.abscessus_ATCC_1997      AAALPMLV-FSGLMNAGQGCVNQTRVLAPRSRYDEVVDGIVGMVSLMGVG
Mflv_0428|M.gilvum_PYR-GCK          DSTLPMLV-FSGLMNSGQACVGQTRILAPRSRYDEVIEKLGEAVRNMAPG
Mvan_0240|M.vanbaalenii_PYR-1       DSTLPMLV-FSGLMNSGQACVGQTRILAPRSRYDEVVEKLAAAAAGMAPG
MSMEG_0309|M.smegmatis_MC2_155      DSTLPMLL-FSGLMNSGQACVGQTRILAPRSRYDEVVEKVAAGVAAMQVG
TH_3591|M.thermoresistible__bu      ETTIPTLLGVSVIPSSGQSCVCQSRFLVPRSRHDEIVDRLVEALRGVKVG
Mb0791|M.bovis_AF2122/97            AAASAVSA-FSACMHAGQGCAITTRLVVPRARYEEAVAIAAATMSSIRPG
MLBr_02573|M.leprae_Br4923          DAAVATAV-TGRVQNNGQSCIAAKRFIAHADIYDEFVEKFVARMETLRVG
                                     :: .     .     **.*   .*.:.    ::* :         :  *

MMAR_0472|M.marinum_M               PPSDPAAQIGSLISEKQRARVEGYIAKGIEEGARLVSGGGRPEGLDNGFF
MUL_1122|M.ulcerans_Agy99           PPSDPAAQIGSLISEKQRARVEGYIAKGIEEGARLVSGGGRPESLDNGFF
MAV_4946|M.avium_104                LPSDPAAQIGSLISEKQRARVEGYIAKGIEEGARLVCGGGRPEGLDSGFF
Rv0223c|M.tuberculosis_H37Rv        PPSDPAAQIGPLISEKQRTRVEGYIAKGIEEGARLVCGGGRPEGLDNGFF
MAB_4484|M.abscessus_ATCC_1997      LPDDPATQVGPLITEKQRTRVEGYIAKGIAEGARLAYGGKRPEGLDGGYF
Mflv_0428|M.gilvum_PYR-GCK          LPDNPAAMIGPLISEKQRDRVEGYIKKGIEEGARVITGGGRPEGLDSGWF
Mvan_0240|M.vanbaalenii_PYR-1       LPDNPAAMIGPLISEKQRDRVEGYIKKGIEEGARVVTGGGRPEGLDSGWY
MSMEG_0309|M.smegmatis_MC2_155      VPDDPAAMVGPLISEKQRERVEGYIKKGIEEGARLVTGGGRPEGLDSGWF
TH_3591|M.thermoresistible__bu      DPHDPDTQMGPLITEAHRRRVLGFIDRAVEQGAKVAFGGGIPEGLDRGWY
Mb0791|M.bovis_AF2122/97            DPNDPGTVCGPLISARQRDRVQGYLDLAVAEGGRFACGGARPADREVGFY
MLBr_02573|M.leprae_Br4923          DPTDPDTDVGPLATESGRAQVEQQVDAAAAAGAVIRCGGKRPD--RPGWF
                                     * :* :  *.* :   * :*   :  .   *. .  **  *     *::

MMAR_0472|M.marinum_M               VQPTVFADVDNKMTIAQEEIFGPVLVVIPYDTEEDAIKIANDSVYGLAGS
MUL_1122|M.ulcerans_Agy99           VQPTVFADVDNKMTIAQEEIFGPVLVVIPYDTKEDAIKIANDSVYGLAGS
MAV_4946|M.avium_104                VQPTVFADVDNKMTIAQEEIFGPVLSIIPYDTEEDAIKIANDSVYGLAGS
Rv0223c|M.tuberculosis_H37Rv        IQPTVFADVDNKMTIAQEEIFGPVLAIIPYDTEEDAIAIANDSVYGLAGS
MAB_4484|M.abscessus_ATCC_1997      VQPTIFADVDNSMTIAQEEIFGPVLSIIAYDSVDEAVKIANDSNYGLAGS
Mflv_0428|M.gilvum_PYR-GCK          VEPTVFADVDNSMTIAQEEIFGPVLSVIPYEDEDDAVRIANDSVYGLAGS
Mvan_0240|M.vanbaalenii_PYR-1       VQPTVFADVDNSMTIAQEEIFGPVLAVIPYEDEDDAVRIANDSVYGLAGS
MSMEG_0309|M.smegmatis_MC2_155      VQPTVFADVDNSMTIAQEEIFGPVLVVIPFEDEDDAVRIANDSVYGLAGS
TH_3591|M.thermoresistible__bu      VEPTLLTNVHTDMEIAREEVFGPVVAVIPYDDEDDAVRIANDSRYGLAGS
Mb0791|M.bovis_AF2122/97            IEPTVIAGLTNDARVAREEIFGPVLTVIAHDGDDDAVRIANDSPYGLSGT
MLBr_02573|M.leprae_Br4923          YPPTVITDITKDMALYTDEVFGPVASVYCATNIDDAIEIANATPFGLGSN
                                      **:::.: ..  :  :*:****  :      ::*: *** : :**...

MMAR_0472|M.marinum_M               VWTSNVPKGIEISEKIRTGTYAIN---WYAFDPCCPFGGYKNSGIGRENG
MUL_1122|M.ulcerans_Agy99           VWTSNVPKGIEISEKIRTGTYAIN---WYAFDPCCPFGGYKNSGIGRENG
MAV_4946|M.avium_104                VWTADVQRGIAVSEKIRTGTYAIN---WYAFDPCCPFGGYKNSGIGRENG
Rv0223c|M.tuberculosis_H37Rv        VWTTDVPKGIKISQQIRTGTYGIN---WYAFDPGSPFGGYKNSGIGRENG
MAB_4484|M.abscessus_ATCC_1997      VWTTDVQKGLEVAAQIRTGTYGIN---WYAFDPSCPFGGYKQSGIGRENG
Mflv_0428|M.gilvum_PYR-GCK          VYTTDNDRALKIARRIRTGTYAVN---MYAFDPCAPFGGYKNSGIGRENG
Mvan_0240|M.vanbaalenii_PYR-1       VYTTDNDRALKIARRIRTGTYAVN---MYAFDPCAPFGGFKNSGIGRENG
MSMEG_0309|M.smegmatis_MC2_155      VYTTDHAKGVEIASKVRTGTYGIN---MYAFDPGAPFGGYKNSGIGRECG
TH_3591|M.thermoresistible__bu      VFTSDIERGFEIARRVRTGTFSVN---SFSADFNSPFGGFKDSGIGREHG
Mb0791|M.bovis_AF2122/97            VYGADPQRAARIASRLRVGTVNVNGGVWYCAD--APFGGYKQSGIGREMG
MLBr_02573|M.leprae_Br4923          AWTQNESEQRHFIDNIVAGQVFING--MTVSYPELPFGGIKRSGYGRELS
                                    .:  :  .   .  .: .*   :*           **** * ** *** .

MMAR_0472|M.marinum_M               PEGVEHFTQQK------SVLMPMGYTLES---------
MUL_1122|M.ulcerans_Agy99           PEGVEHFTQQK------SVLMPMGYTLES---------
MAV_4946|M.avium_104                PEGVEHFTQQK------SVLMPMGYTLEG---------
Rv0223c|M.tuberculosis_H37Rv        PEGVEHFTQQK------SVLLPMGYTVA----------
MAB_4484|M.abscessus_ATCC_1997      PEGIEEYCELK------SVLLPMGYTLESI--------
Mflv_0428|M.gilvum_PYR-GCK          WEGIEAYCEQK------SILLPFGYTPPAS--------
Mvan_0240|M.vanbaalenii_PYR-1       WEGIEAYCEPK------SILLPFGYTPAT---------
MSMEG_0309|M.smegmatis_MC2_155      PEGIAGYCESK------SVLLPFGYTPE----------
TH_3591|M.thermoresistible__bu      VAGFEEYLVPKTISVDPSIRIPESVVAKADRVVDGAGR
Mb0791|M.bovis_AF2122/97            LLGFEEYLEAK--------LIATAAN------------
MLBr_02573|M.leprae_Br4923          THGIREFCNIK------TVWIA----------------
                                      *.  :   *         :.