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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4142 | - | - | 100% (501) | cytochrome p450 |
| M. thermoresistible (build 8) | TH_4542 | - | e-146 | 62.30% (382) | PUTATIVE cytochrome P450 |
| M. thermoresistible (build 8) | TH_2718 | - | e-116 | 54.55% (385) | PUTATIVE cytochrome P450 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1806 | cyp144 | 1e-43 | 33.93% (389) | cytochrome p450 144 CYP144 |
| M. gilvum PYR-GCK | Mflv_1587 | - | 1e-180 | 76.75% (400) | cytochrome P450 |
| M. tuberculosis H37Rv | Rv1777 | cyp144 | 2e-43 | 33.93% (389) | cytochrome p450 144 CYP144 |
| M. leprae Br4923 | MLBr_02088 | - | 7e-36 | 32.53% (289) | putative cytochrome p450 |
| M. abscessus ATCC 19977 | MAB_1216c | - | 1e-42 | 30.28% (393) | cytochrome P450 |
| M. marinum M | MMAR_4694 | cyp150A6 | 1e-154 | 66.32% (383) | cytochrome P450 150A6 Cyp150A6 |
| M. avium 104 | MAV_0849 | - | 1e-176 | 77.81% (383) | cytochrome p450 |
| M. smegmatis MC2 155 | MSMEG_6030 | - | 0.0 | 81.65% (387) | cytochrome p450 |
| M. ulcerans Agy99 | MUL_0314 | cyp150A6 | 1e-152 | 65.54% (383) | cytochrome P450 150A6 Cyp150A6 |
| M. vanbaalenii PYR-1 | Mvan_5170 | - | 0.0 | 78.81% (387) | cytochrome P450 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1806|M.bovis_AF2122/97 -MRRSPKGSPGAVLDLQRRVDQAVSADHAELMTIAKDANTFFGAESVQDP
Rv1777|M.tuberculosis_H37Rv -MRRSPKGSPGAVLDLQRRVDQAVSADHAELMTIAKDANTFFGAESVQDP
Mflv_1587|M.gilvum_PYR-GCK -------------------------------MTDLATVDFFSDYAISQDP
Mvan_5170|M.vanbaalenii_PYR-1 -------------------------------MTDLASADFFSDYALSQDP
MSMEG_6030|M.smegmatis_MC2_155 -------------------------------MTDLASVDYFSDPAVAQDP
TH_4142|M.thermoresistible__bu -------------------------------MTDLAAVDYFSDEAVSQNP
MAV_0849|M.avium_104 -------------------------------MTDLAQVDYFTDADVAQDP
MMAR_4694|M.marinum_M -------------------------------MSSYESIDFFTDPSLIPDP
MUL_0314|M.ulcerans_Agy99 -------------------------------MSSYESIDFFTDPSLIPDP
MLBr_02088|M.leprae_Br4923 MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLIDPGTRADP
MAB_1216c|M.abscessus_ATCC_199 --------------------------MTVAETSAVPLVFDPYDYDFHEDP
. :*
Mb1806|M.bovis_AF2122/97 YPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSN-----LT
Rv1777|M.tuberculosis_H37Rv YPLYERMRAAGSVHRIANSDFYAVCGWDAVNEAIGRPEDFSSN-----LT
Mflv_1587|M.gilvum_PYR-GCK YAYWDFLREQSPVYREPHYGVVAVTGYKEVLAAFKDHDSFSAVNAIGGPF
Mvan_5170|M.vanbaalenii_PYR-1 HPYWDHLREQNPVYREPHYGVVAVTGYQEVLAAFKDHDSFSAVNAIGGPF
MSMEG_6030|M.smegmatis_MC2_155 YEYYDFLRSRGPVTTEPHYGVVAVTGYQEVMAAFKDHDSFSAVNAIGGPF
TH_4142|M.thermoresistible__bu YEYYEYLRSQGPVFREPHHGVVAVTGYEEVLAAFKNHECFSAVNAIGGPF
MAV_0849|M.avium_104 YDYWDYLREQGPVFREPHYGVVAVTGYQEVQAAFKDVESFSAVNAIGGPF
MMAR_4694|M.marinum_M HPYFDYLRSQSPVLRLPQYGVVAVTGYEEATAVYKDTDSFSNCVALGGPF
MUL_0314|M.ulcerans_Agy99 HPYFDYLRRQSPVLRLPQYGVVAVTGYEEATAVYKDTDSFSNCVALGGPF
MLBr_02088|M.leprae_Br4923 FPVYRALIDYGPMQLPG-MPLTVFSSFSDCDEALRHPLSASDRLKATLAQ
MAB_1216c|M.abscessus_ATCC_199 YPYYRRLRDEAPLYRNDDLKFWALSRHHDVLQGFRNSEALSNANGVSMDK
. : : .: . .. *
Mb1806|M.bovis_AF2122/97 ATMTYTAEGTAKPFEMDPLGGPT---HVLATADDPAHAVHRKLVLRHLAA
Rv1777|M.tuberculosis_H37Rv ATMTYTAEGTAKPFEMDPLGGPT---HVLATADDPAHAVHRKLVLRHLAA
Mflv_1587|M.gilvum_PYR-GCK PPLPFTPEGDDITEQIEAHRHLFPIYEHMVVMDPPAHERARSLLNKLLTP
Mvan_5170|M.vanbaalenii_PYR-1 PPLPFTPEGDDITEQIEAHRHLFPIHEHLVVMDPPAHERARSLLNKLLTP
MSMEG_6030|M.smegmatis_MC2_155 PPLPFTPEGDDITEQIEAHRHLFPIHEHMVVMDPPAHERARSLLSKLLTP
TH_4142|M.thermoresistible__bu PPLPFEPEGDDISEQIEAHRHEFPIHEHMVVMDPPQHTRARSLLTKLLTP
MAV_0849|M.avium_104 PPLPFTPEGDDISELIEAHRHEFPIFEHMVVMDPPEHDKARSLLGRLLTP
MMAR_4694|M.marinum_M PPLPFAPNGDDVNAQIDAHREQFPMYEHMVTMDPPEHSRARSILSRLLTP
MUL_0314|M.ulcerans_Agy99 PPLPFTPNGDDVNAQIDAHREQFPMYEHMVTMDPPEHSRARSILSRLLTP
MLBr_02088|M.leprae_Br4923 QAIAAGAEPRPF------------YASSFMFLDPPDHTRLRKLVSKAFAP
MAB_1216c|M.abscessus_ATCC_199 ASFGPHAK----------------LVMSFLAMDDPEHLRLRALVSKGFTP
.: .: : * * * * :: : ::.
Mb1806|M.bovis_AF2122/97 KRIRVMEQFTVQAADRLWVDGMQ----DGCIEWMGAMANRLPMMVVAELI
Rv1777|M.tuberculosis_H37Rv KRIRVMEQFTVQAADRLWVDGMQ----DGCIEWMGAMANRLPMMVVAELI
Mflv_1587|M.gilvum_PYR-GCK RRLKENEDYMWRLVDSQIDQVID----KGRCEFLTEYAKPFATSAIIDLL
Mvan_5170|M.vanbaalenii_PYR-1 RRLKENEDYMWQLVDSQIDQVIG----KGRCEFLSEYAKPFATSAIIDLL
MSMEG_6030|M.smegmatis_MC2_155 RRLKENEDFMWQLVDRQLDAIIGNQADEGRCEFLSEYAKPFATSAIIDLL
TH_4142|M.thermoresistible__bu RRLKENEDFMWQLADRQLDEFIA----AGRCEFLSEYAKPFATMAIIDLL
MAV_0849|M.avium_104 RRLQENKDYIWQLADRQFDEFIA----NGHCEFLSEYAKPFATLAIADLL
MMAR_4694|M.marinum_M SRLKQNEEFMWRLADRQLDEFLG----AGECEFISEYAKPFATLVIADLL
MUL_0314|M.ulcerans_Agy99 SRLKQNEEFMWRLADRQLDEFLG----AAECEFISEYAKPFATLVIADLL
MLBr_02088|M.leprae_Br4923 KVVQALEGDIAALVDSLLDKGAAAG----QFDVIADLAFPLAVAVICRLL
MAB_1216c|M.abscessus_ATCC_199 RRIRELEGQVVALARTHLDRALANAS-DRSFDFIAEYAGKLPMDVISELM
:: : . : : * :. .: *:
Mb1806|M.bovis_AF2122/97 GLPDPDIAQLVKWGYAATQLLEGLVENDQL-----VAAGVALMELSGYIF
Rv1777|M.tuberculosis_H37Rv GLPDPDIAQLVKWGYAATQLLEGLVENDQL-----VAAGVALMELSGYIF
Mflv_1587|M.gilvum_PYR-GCK GVPEEDRPEFLAALGAEQPDGARVGALDGE-----PVGLDPLQYLDDKFL
Mvan_5170|M.vanbaalenii_PYR-1 GVPEEDRPEFLAALGAEQPDGARVGALDGE-----PVGLDPLQYLDDKFA
MSMEG_6030|M.smegmatis_MC2_155 GVPEEDRAEFLEALGAAPREGARVGALDGE-----PVGLDPLQYLDCKFA
TH_4142|M.thermoresistible__bu GVPEEDRAEFRQALGADARPGSRVGALDGE-----PVGLNPLEYLDDKFS
MAV_0849|M.avium_104 GVPDEDRPQIRRNLGAGNAPGARVGALDHE-----PVGSNPLQYLDDLFS
MMAR_4694|M.marinum_M GVPEDDRKDFRVVLGADRMG--RVGALDHE-----SVGVNPLQWLDDKFS
MUL_0314|M.ulcerans_Agy99 GVPEDDRKDFRVVLGADRMG--RVGALDHE-----SVGVNPLQWLDDKFS
MLBr_02088|M.leprae_Br4923 GVPYEDAPEFGRVSALLVQSVDPFITITGEPPEATEERLRAGVWLRDYLE
MAB_1216c|M.abscessus_ATCC_199 GVPESDRARIRELADGVMHREDGLADVP-------PEAIQASFDLMTYYI
*:* * : . . *
Mb1806|M.bovis_AF2122/97 EQFDRAAADPRDNLLGELATACASG--ELDTLTAQVMMVTLFAAGGESTA
Rv1777|M.tuberculosis_H37Rv EQFDRAAADPRDNLLGELATACASG--ELDTLTAQVMMVTLFAAGGESTA
Mflv_1587|M.gilvum_PYR-GCK GYLTERRREPRGDVLSGMATAVYPDGSTPDLIEVVKPATFLFAAGQETVT
Mvan_5170|M.vanbaalenii_PYR-1 GYLAERRREPRGDVLSGMATAVYPDGSTPELIEVVKPATFLFAAGQETVT
MSMEG_6030|M.smegmatis_MC2_155 GYLAERRREPRGDVLSGMATATYPDGSTPDLMEVVKPATFLFAAGQETVT
TH_4142|M.thermoresistible__bu EYIAERRREPRGDVLSGMAAATYPDGSTPELLEVVRPATFLFAAGQETVT
MAV_0849|M.avium_104 GYIADRRERPRDDVLTGLATATYPDGSTPPLLEVVRPATFLFAAGQETVT
MMAR_4694|M.marinum_M AYIEDRRRQPRNDVLTALATATYPDGSTPEVIDVVRSATFLFAAGQETTA
MUL_0314|M.ulcerans_Agy99 AYIEDRRRRPRNDVLTALATATYPDGSTPEIIDVVRWATFLFAAGQETTA
MLBr_02088|M.leprae_Br4923 QLVKCRRGTPGEDLISRLIELDESG-DQLTEEEIIATCGLLLVAGHETTV
MAB_1216c|M.abscessus_ATCC_199 EMVRERRRRPTEDLTSALLQAEIDG-DRLTDEEVLAFLFLMVIAGNETTT
. * :: : . :. ** *:..
Mb1806|M.bovis_AF2122/97 ALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGQYRHVRN
Rv1777|M.tuberculosis_H37Rv ALLGSAVWILATRPDIQQQVRANPELLGAFIEETLRYEPPFRGHYRHVRN
Mflv_1587|M.gilvum_PYR-GCK KLLSAAMKTLGEHPEYQPYLREHPDRIPAFIEESLRMHSPTKIDFRLVRK
Mvan_5170|M.vanbaalenii_PYR-1 KLLSAAVKTLAEQPEYQRILRAHPDRIPTFIEESLRMNAPTKVDFRLVRK
MSMEG_6030|M.smegmatis_MC2_155 KLLSSAVQTLAERPEFQERLRKEPDLIPVFIEEALRTQSPTKVDFRLARK
TH_4142|M.thermoresistible__bu KLLSSAIKTLGERPEYQQMLRENRSLIPTFIEESLRMESPTKVDFRLARK
MAV_0849|M.avium_104 KLLSAAVQVLGDQPELQAQLRADRGLIGPFIEEALRMQSPTKVDFRLARK
MMAR_4694|M.marinum_M KLLTAAMRVLGDRPDIQRRLRENRSLIPNFIEESLRMDSPVKSDSRLARK
MUL_0314|M.ulcerans_Agy99 KQLTAAMRVLGDRPDIQRQLRENRSLIPNFIEESLRMDSPVKSDSRLARK
MLBr_02088|M.leprae_Br4923 NLIANAVLAMLRNPSQWKALSSNPQRAPLVVEETLRYDPAIHLIGRVAAK
MAB_1216c|M.abscessus_ATCC_199 KLLANAVYWGHRNPDQLATVHADHDRIPLWVEESLRYDTSSQILARTVAE
: *: .*. : . :**:** ... : * . :
Mb1806|M.bovis_AF2122/97 ATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGK
Rv1777|M.tuberculosis_H37Rv ATTLDGTELPADSHLLLLWGAANRDPAQFEAPGEFRLDRAGGKGHISFGK
Mflv_1587|M.gilvum_PYR-GCK TTTLGGMHLKAGTIVMLCLGAANRDPAKFDDPHEFRPDRKNVREHIAFGR
Mvan_5170|M.vanbaalenii_PYR-1 TTTLGGVHLKAGTIVMLCLGAANRDPRKFEDPHEFRPERKNVREHIAFGR
MSMEG_6030|M.smegmatis_MC2_155 TTTLGGVEIKAGTVLMLCLGAANRDPRKFEDPHEFRIDRPNVREHIAFGR
TH_4142|M.thermoresistible__bu TTELGGVRIAAGTVLMLCLGAANRDPRKFEQPHEFRPDRRNVREHIAFGR
MAV_0849|M.avium_104 TTTLGGVHIPAGTVIMLCLGAANRDPRKFENPNEFRIDRKNVREHIAFGR
MMAR_4694|M.marinum_M RTTVGGLDIAAGTVVMVLPGAANRDPRRFEDPHEFRLDRPNVREHMAFAR
MUL_0314|M.ulcerans_Agy99 RTTVGGLDIAAGTVVMVLSGAANRDPRRFEDPHEFRLDRPNVREHMAFAR
MLBr_02088|M.leprae_Br4923 DMTIGQTTLTEGDTMVLLLAAANRDPAVYSRPDEFDPDRPS-SRHLAFAV
MAB_1216c|M.abscessus_ATCC_199 DITVYDTKIPAGDILLLLPGSANRDDRVFDDADQYRIGREIGAKLVSFGS
: : . ::: .:**** :. . :: * ::*.
Mb1806|M.bovis_AF2122/97 GAHFCVGAALARLEARIVLRLLLD--------------------------
Rv1777|M.tuberculosis_H37Rv GAHFCVGAALARLEARIVLRLLLD--------------------------
Mflv_1587|M.gilvum_PYR-GCK GIHTCAGAPLARVEGQITVRRWLD--------------------------
Mvan_5170|M.vanbaalenii_PYR-1 GIHTCAGAPLARVEGQITVRRWLD--------------------------
MSMEG_6030|M.smegmatis_MC2_155 GIHTCAGAPLARVEGQITVRRMLD--------------------------
TH_4142|M.thermoresistible__bu GIHSCAGAPLARVEGRITVERVLXGADRPFSRRLRLHGRSRSGGLRRTGD
MAV_0849|M.avium_104 GIHTCAGAPLARVEGQITINRLLD--------------------------
MMAR_4694|M.marinum_M GVHSCPGGPLARVEGRVSLERILD--------------------------
MUL_0314|M.ulcerans_Agy99 GVHSCPGGPLARVEGRVSLERILD--------------------------
MLBr_02088|M.leprae_Br4923 GSHFCLGAALARLEATVTLSAISA--------------------------
MAB_1216c|M.abscessus_ATCC_199 GAHFCLGAHLARMEAKVALTELFT--------------------------
* * * *. ***:*. : :
Mb1806|M.bovis_AF2122/97 ----------------RTSVIEAADVG-----------------------
Rv1777|M.tuberculosis_H37Rv ----------------RTSVIEAADVG-----------------------
Mflv_1587|M.gilvum_PYR-GCK ----------------RTSEIRLDEA-----------------VHGPAG-
Mvan_5170|M.vanbaalenii_PYR-1 ----------------RTDEIHLDES-----------------VHGPAG-
MSMEG_6030|M.smegmatis_MC2_155 ----------------RLRDIRIDAT-----------------RHGPAD-
TH_4142|M.thermoresistible__bu RHRITGVTRHARGWSRREGDVQLGQAPQQKRRLVPVRAVTGGSVHGVVDR
MAV_0849|M.avium_104 ----------------RTSELRINEA-----------------KHGPAS-
MMAR_4694|M.marinum_M ----------------RMLDIAINED-----------------RHGPAD-
MUL_0314|M.ulcerans_Agy99 ----------------RMLDIAINED-----------------RHGPAD-
MLBr_02088|M.leprae_Br4923 ----------------RFPQVQLAG-------------------------
MAB_1216c|M.abscessus_ATCC_199 ----------------RISGYEIDER------------------------
*
Mb1806|M.bovis_AF2122/97 ----------GWLPSILVRR------IERLELAVQ-----
Rv1777|M.tuberculosis_H37Rv ----------GWLPSILVRR------IERLELAVQ-----
Mflv_1587|M.gilvum_PYR-GCK ------DHRFSYDPTFLLRG------LSELRIEYTAAS--
Mvan_5170|M.vanbaalenii_PYR-1 ------QHHFAYDPTFLLRG------LSQLNIEFTAAT--
MSMEG_6030|M.smegmatis_MC2_155 ------SRTYAYEPTFLLRG------LTKLHIEYTPA---
TH_4142|M.thermoresistible__bu QIAHPVQHPFHGDPPXGGGGGERPISTGPPRRPNRPATPT
MAV_0849|M.avium_104 ------SRQYRYESTFLLRG------LTELHIEFTQAG--
MMAR_4694|M.marinum_M ------DRRYTYEPTYILRG------LTELHITFTPAG--
MUL_0314|M.ulcerans_Agy99 ------DRRYTYEPTYILRG------LTELHITFTPAG--
MLBr_02088|M.leprae_Br4923 --------ELVYKPNVAMRG------MSALPVQV------
MAB_1216c|M.abscessus_ATCC_199 --------NSVRVHSSNVRG------FAHLPMTVQLREGR