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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_2718 | - | - | 100% (423) | cytochrome P450 |
M. thermoresistible (build 8) | TH_4542 | - | e-144 | 58.02% (424) | PUTATIVE cytochrome P450 |
M. thermoresistible (build 8) | TH_4148 | - | e-125 | 52.49% (421) | PUTATIVE cytochrome P450 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0789c | cyp123 | 2e-39 | 31.64% (373) | cytochrome P450 123 |
M. gilvum PYR-GCK | Mflv_4149 | - | 0.0 | 80.82% (417) | cytochrome P450 |
M. tuberculosis H37Rv | Rv0766c | cyp123 | 2e-39 | 31.64% (373) | cytochrome P450 123 |
M. leprae Br4923 | MLBr_02088 | - | 2e-37 | 31.69% (325) | putative cytochrome p450 |
M. abscessus ATCC 19977 | MAB_1939 | - | 1e-40 | 30.84% (428) | cytochrome P450 |
M. marinum M | MMAR_4694 | cyp150A6 | 1e-142 | 56.97% (423) | cytochrome P450 150A6 Cyp150A6 |
M. avium 104 | MAV_0964 | - | 1e-141 | 57.78% (424) | cytochrome p450 |
M. smegmatis MC2 155 | MSMEG_4780 | - | 1e-150 | 61.70% (423) | cytochrome p450 |
M. ulcerans Agy99 | MUL_0314 | cyp150A6 | 1e-140 | 56.26% (423) | cytochrome P450 150A6 Cyp150A6 |
M. vanbaalenii PYR-1 | Mvan_4141 | - | 1e-142 | 58.41% (428) | cytochrome P450 |
CLUSTAL 2.0.9 multiple sequence alignment TH_2718|M.thermoresistible__bu -------------------------------VTDFDTVDFFTDESLVGDP Mflv_4149|M.gilvum_PYR-GCK -----------------------MTDHPDADGIDFETVDYFTDAALVPDP MSMEG_4780|M.smegmatis_MC2_155 -------------------MTDSTATDPAATTPDFDTVDYFTDQSLVPDP Mvan_4141|M.vanbaalenii_PYR-1 -------------------------------MSDFDTIDYFTDPSLVPDP MMAR_4694|M.marinum_M -------------------------------MSSYESIDFFTDPSLIPDP MUL_0314|M.ulcerans_Agy99 -------------------------------MSSYESIDFFTDPSLIPDP MAV_0964|M.avium_104 -------------------------------MSNFDSIDFFTDPSLVPDP Mb0789c|M.bovis_AF2122/97 ---------------------------MTVRVGDPELVLDPYDYDFHEDP Rv0766c|M.tuberculosis_H37Rv ---------------------------MTVRVGDPELVLDPYDYDFHEDP MLBr_02088|M.leprae_Br4923 MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLIDPGTRADP MAB_1939|M.abscessus_ATCC_1997 -----------------------------------MNTDELFDPQVLEDP * ** TH_2718|M.thermoresistible__bu YSYFEHLRSKCPVVEATPHKVLAVTGYEEALEVYRNP-AFSSCVSVAGPF Mflv_4149|M.gilvum_PYR-GCK YPYFDHLRSKCPVTQATPFNVLAVTGYTEALSVYKNP-AFSSCNSVAGPF MSMEG_4780|M.smegmatis_MC2_155 HPYFDHLRSKCPVVREPHYGVLAITSFEEATTVLKDTETFSSCIAVGGPF Mvan_4141|M.vanbaalenii_PYR-1 HPYFDHLRSKCPVVREPHYGVLAVTGYEEAATVLKDSDTFSSCIAVAGPF MMAR_4694|M.marinum_M HPYFDYLRSQSPVLRLPQYGVVAVTGYEEATAVYKDTDSFSNCVALGGPF MUL_0314|M.ulcerans_Agy99 HPYFDYLRRQSPVLRLPQYGVVAVTGYEEATAVYKDTDSFSNCVALGGPF MAV_0964|M.avium_104 HPYFDYLRSQNPVLRLPHYGVVAITGYEEATEVYKDPETFSNIVALGGPF Mb0789c|M.bovis_AF2122/97 YPYYRRLRDEAPLYRNEERNFWAVSRHHDVLQGFRDSTALSNAYGVSLDP Rv0766c|M.tuberculosis_H37Rv YPYYRRLRDEAPLYRNEERNFWAVSRHHDVLQGFRDSTALSNAYGVSLDP MLBr_02088|M.leprae_Br4923 FPVYRALIDYGPMQLPG-MPLTVFSSFSDCDEALRHPLSASDRLKATLAQ MAB_1939|M.abscessus_ATCC_1997 YPFYRRLRETAPVWPVGDSGFYFVSRWDLVVEATERAEDFSSNLTAALMK .. : * *: . .: . . *. TH_2718|M.thermoresistible__bu SGMPFGPDGRDDVSDLIEQYRDGVPMAEHITSQDPPLHTRTRGLLNKLIT Mflv_4149|M.gilvum_PYR-GCK SGMPFGPGESDDVTDLIEQHRAAVPMAEHITSQDPPLHTRTRGLLSRLIT MSMEG_4780|M.smegmatis_MC2_155 PPLPFTPEG-DDITGQIEQHRTQLPMFEHMVTMDPPEHTNARSLLNRLLT Mvan_4141|M.vanbaalenii_PYR-1 PPLPFTPEG-DDITGQIAAHRSQMPMFEHMVTMDPPDHTNARSLLNRLLT MMAR_4694|M.marinum_M PPLPFAPNG-DDVNAQIDAHREQFPMYEHMVTMDPPEHSRARSILSRLLT MUL_0314|M.ulcerans_Agy99 PPLPFTPNG-DDVNAQIDAHREQFPMYEHMVTMDPPEHSRARSILSRLLT MAV_0964|M.avium_104 PPLPFTPEG-DDISAQIDAHRSSFPMFEHMVTMDPPEHTKARSVLAKLLT Mb0789c|M.bovis_AF2122/97 SSRTS-----------------EAYRVMSMLAMDDPAHLRMRTLVSKGFT Rv0766c|M.tuberculosis_H37Rv SSRTS-----------------EAYRVMSMLAMDDPAHLRMRTLVSKGFT MLBr_02088|M.leprae_Br4923 QAIAAGAEP-------------RPFYASSFMFLDPPDHTRLRKLVSKAFA MAB_1939|M.abscessus_ATCC_1997 SAEGLAVAP----------MGPPADPTHVLATGDDPLHHAHRRLVLPTLV : * * * * :: :. TH_2718|M.thermoresistible__bu PKRLKENEEFMWRLADQQLDRFLDR---GSAEFLEDYAKPFSLLVIADLL Mflv_4149|M.gilvum_PYR-GCK PKRLKENEDFMWRLADRQLDTFIGR---GSAEFLTDYAKPFSLLVIADLL MSMEG_4780|M.smegmatis_MC2_155 PKRLKENEDFMWRLADECLDDFIDD---GSCEFLKQYAKPFSLLVIADLL Mvan_4141|M.vanbaalenii_PYR-1 PSRLKENEDFMWRLADEVLDDIISRDPVGRCEFLSAYAKPFSLLVIADML MMAR_4694|M.marinum_M PSRLKQNEEFMWRLADRQLDEFLGA---GECEFISEYAKPFATLVIADLL MUL_0314|M.ulcerans_Agy99 PSRLKQNEEFMWRLADRQLDEFLGA---AECEFISEYAKPFATLVIADLL MAV_0964|M.avium_104 PSRLKQNEEFMWRLADRQLDEFLHN---GECEFIAEYSKPFATLVIADLL Mb0789c|M.bovis_AF2122/97 PRRIRELEPQVLELARIHLDSALQT---ESFDFVAEFAGKLPMDVISELI Rv0766c|M.tuberculosis_H37Rv PRRIRELEPQVLELARIHLDSALQT---ESFDFVAEFAGKLPMDVISELI MLBr_02088|M.leprae_Br4923 PKVVQALEGDIAALVDSLLDKGAAA---GQFDVIADLAFPLAVAVICRLL MAB_1939|M.abscessus_ATCC_1997 ARRITALEPVMAQTGSCLWERGVNG---DGIDWMAAMGDALPMTMVARLI . : * : : : : . :. ::. :: TH_2718|M.thermoresistible__bu GVPAADHEEFK-----AAFAL----ETVGELGKDAPTSHNPLEWLNDKFR Mflv_4149|M.gilvum_PYR-GCK GVPAEDHEQFK-----AVFAG----ETVGELGKEAPTTHNPLQWLNDKFH MSMEG_4780|M.smegmatis_MC2_155 GVPEEDHDEFR-----HVLGAPRPGAIVGSLDG-DQLAMNPLAWLDDKFV Mvan_4141|M.vanbaalenii_PYR-1 GVPEADHEEFR-----TVLGAPRPGANVGSLDHSDLVGANPLEWLDEKFI MMAR_4694|M.marinum_M GVPEDDRKDFR-----VVLGADRMG-RVGALDH-ESVGVNPLQWLDDKFS MUL_0314|M.ulcerans_Agy99 GVPEDDRKDFR-----VVLGADRMG-RVGALDH-ESVGVNPLQWLDDKFS MAV_0964|M.avium_104 GVPEEDHTQFR-----TVLGADRPGARVGALDH-ETVGINPLEWLDDKFC Mb0789c|M.bovis_AF2122/97 GVPDTDRARIRALADAVLHRED---GVADVPP----PAMAASIELMRYYA Rv0766c|M.tuberculosis_H37Rv GVPDTDRARIRALADAVLHRED---GVADVPP----PAMAASIELMRYYA MLBr_02088|M.leprae_Br4923 GVPYEDAPEFGRVSALLVQSVDPFITITGEPPEATEERLRAGVWLRDYLE MAB_1939|M.abscessus_ATCC_1997 GLPAGDVPQLVQWG----YSSTEMLGGLNTPQR-QAQVVTDTMHLVLYLR *:* * : . * TH_2718|M.thermoresistible__bu AYIEDRRRAPRADVLTELAHARYEDGSTPDIDDVMNVSTFLFAAGTETTT Mflv_4149|M.gilvum_PYR-GCK AYIEDRRREPRDDVLTELAQAKHEDGSTPDIEDVMNLSTFLFAAGTETTT MSMEG_4780|M.smegmatis_MC2_155 RYLEDRRKEPRDDVLTALATAKYPDGSTPEVIDVVRSATFLFAAGQETTT Mvan_4141|M.vanbaalenii_PYR-1 GYLEDRRKEPRDDVLTALATAKYPDGSTPPVIEVVRSATFLFAAGQETTT MMAR_4694|M.marinum_M AYIEDRRRQPRNDVLTALATATYPDGSTPEVIDVVRSATFLFAAGQETTA MUL_0314|M.ulcerans_Agy99 AYIEDRRRRPRNDVLTALATATYPDGSTPEIIDVVRWATFLFAAGQETTA MAV_0964|M.avium_104 NYIEERRREPRADVLTFLAEAKYPDGSTPPVIEVVRSATFLFAAGQETTA Mb0789c|M.bovis_AF2122/97 DLIAEFRRRPANNLTSALLAAEL-DGDRLSDQEIMAFLFLMVIAGNETTT Rv0766c|M.tuberculosis_H37Rv DLIAEFRRRPANNLTSALLAAEL-DGDRLSDQEIMAFLFLMVIAGNETTT MLBr_02088|M.leprae_Br4923 QLVKCRRGTPGEDLISRLIELDE-SGDQLTEEEIIATCGLLLVAGHETTV MAB_1939|M.abscessus_ATCC_1997 EHLEEELAAPGDDLLGYLAQACNRGDISLDIG--VMILVQLVGAGGESTA : * :: * .. : :. ** *:*. TH_2718|M.thermoresistible__bu KLVSFAVRSIAEDQRLQQELRADRSRIPAFLEETLRMESPVKAHFRMART Mflv_4149|M.gilvum_PYR-GCK KLVSSAVRFIADNPGYEAMLRRDRSKIPAFLEETLRLESPVKSHFRMAAT MSMEG_4780|M.smegmatis_MC2_155 KLLSASLRVLGDRPDIQQALREDRSRIPTFVEEALRMDAPVKSQFRLAKK Mvan_4141|M.vanbaalenii_PYR-1 KLLSASLRVLGDHPDIQERLRRDRSRIPIFVEEALRMDAPVKSQFRLAKK MMAR_4694|M.marinum_M KLLTAAMRVLGDRPDIQRRLRENRSLIPNFIEESLRMDSPVKSDSRLARK MUL_0314|M.ulcerans_Agy99 KQLTAAMRVLGDRPDIQRQLRENRSLIPNFIEESLRMDSPVKSDSRLARK MAV_0964|M.avium_104 KLLSAALQVLGDRPDIQQQLREDRSLIPAFIEESLRMESPVKSDSRLARR Mb0789c|M.bovis_AF2122/97 KLLANAVYWAAHHPGQLARVFADHSRIPMWVEETLRYDTSSQILARTVAH Rv0766c|M.tuberculosis_H37Rv KLLANAVYWAAHHPGQLARVFADHSRIPMWVEETLRYDTSSQILARTVAH MLBr_02088|M.leprae_Br4923 NLIANAVLAMLRNPSQWKALSSNPQRAPLVVEETLRYDPAIHLIGRVAAK MAB_1939|M.abscessus_ATCC_1997 GLMGNAVRILGENPRLQQRIRENRALLPTFLEEALRLESPFRGHHRHVLT : :: : : * :**:** :.. : * . TH_2718|M.thermoresistible__bu TTTIGDVKVPAGTTIMLLPGACNRDPRKFIDPDSFRPDRPNVREQIAFIR Mflv_4149|M.gilvum_PYR-GCK STTIGDVDVPAGTTVMVLPGACNRDARKFADPNSFRPDRQNVREQIAFIR MSMEG_4780|M.smegmatis_MC2_155 TTQLGGVDVPAGTTLMVCPGAVNRDPVRFEDPHTFSLDRKNVREHIAFGR Mvan_4141|M.vanbaalenii_PYR-1 NTRVGDMDVPAGTTMMVCPGAVNRDPSRFEHPHEFDLDRKNVREHIAFGR MMAR_4694|M.marinum_M RTTVGGLDIAAGTVVMVLPGAANRDPRRFEDPHEFRLDRPNVREHMAFAR MUL_0314|M.ulcerans_Agy99 RTTVGGLDIAAGTVVMVLSGAANRDPRRFEDPHEFRLDRPNVREHMAFAR MAV_0964|M.avium_104 ATTIGGVDIPAGTVVMILPGAANRDPRRFENPHEFDLRRKNVREHMAFAR Mb0789c|M.bovis_AF2122/97 DLTLYDTTIPEGEVLLLLPGSANRDDRVFDDPDDYRIGREIGCKLVSFGS Rv0766c|M.tuberculosis_H37Rv DLTLYDTTIPEGEVLLLLPGSANRDDRVFDDPDDYRIGREIGCKLVSFGS MLBr_02088|M.leprae_Br4923 DMTIGQTTLTEGDTMVLLLAAANRDPAVYSRPDEFDPDRPS-SRHLAFAV MAB_1939|M.abscessus_ATCC_1997 DTTLGGVQLPAGSHLTLLWGAANRDPAIFEDPDVLRLDRPSPRGHITFGK : :. * : : .: *** : *. * ::* TH_2718|M.thermoresistible__bu GPHSCPGAPLARAEGRISLNRILDRMTDIRISQAHHGPAEHRRYTYEPTF Mflv_4149|M.gilvum_PYR-GCK GAHSCPGAPLARAEGRISLERILDRMQDITISEDHHGPAGDRRYAYEPTF MSMEG_4780|M.smegmatis_MC2_155 GVHSCPGGPLARVEGRVSLERILDRMADIRIDEEHHGPADNRRYTYEPTY Mvan_4141|M.vanbaalenii_PYR-1 GVHSCPGGPLARVEGRVSIERILDRMGDIAIDEELHGPPGARRYNYEPTF MMAR_4694|M.marinum_M GVHSCPGGPLARVEGRVSLERILDRMLDIAINEDRHGPADDRRYTYEPTY MUL_0314|M.ulcerans_Agy99 GVHSCPGGPLARVEGRVSLERILDRMLDIAINEDRHGPADDRRYTYEPTY MAV_0964|M.avium_104 GVHSCPGGPLARVEGRVSIERILDRMPHIEINETHHGPAGDRRYTYEPTY Mb0789c|M.bovis_AF2122/97 GAHFCLGAHLARMEARVALGALLRRIRNYEVDDD--------NVVRVHSS Rv0766c|M.tuberculosis_H37Rv GAHFCLGAHLARMEARVALGALLRRIRNYEVDDD--------NVVRVHSS MLBr_02088|M.leprae_Br4923 GSHFCLGAALARLEATVTLSAISARFPQVQLAGE--------LVYKPN-V MAB_1939|M.abscessus_ATCC_1997 GLHFCVGAALARLEARTAINLLLDRTREFAIKPD--------GAHWVPSI * * * *. *** *. :: : * . : TH_2718|M.thermoresistible__bu IMRGLNELHIEFSPGS------ Mflv_4149|M.gilvum_PYR-GCK IMRGLSELHITFTEKEH----- MSMEG_4780|M.smegmatis_MC2_155 ILRGLTDLHIKFEPVR------ Mvan_4141|M.vanbaalenii_PYR-1 ILRGLTDLNITFTPVR------ MMAR_4694|M.marinum_M ILRGLTELHITFTPAG------ MUL_0314|M.ulcerans_Agy99 ILRGLTELHITFTPAG------ MAV_0964|M.avium_104 ILRGLSELHLTFTTADAVAPVG Mb0789c|M.bovis_AF2122/97 NVRGFAHLPISVQAR------- Rv0766c|M.tuberculosis_H37Rv NVRGFAHLPISVQAR------- MLBr_02088|M.leprae_Br4923 AMRGMSALPVQV---------- MAB_1939|M.abscessus_ATCC_1997 MVRRHQKLELEVSAA------- :* * : .