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M. thermoresistible (build 8) TH_2718 (-)

annotation: cytochrome P450
coordinates: 472230 - 473498
length: 423

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2718--100% (423)cytochrome P450
M. thermoresistible (build 8)TH_4542-e-14458.02% (424) PUTATIVE cytochrome P450
M. thermoresistible (build 8)TH_4148-e-12552.49% (421) PUTATIVE cytochrome P450

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0789ccyp1232e-3931.64% (373) cytochrome P450 123
M. gilvum PYR-GCKMflv_4149-0.080.82% (417) cytochrome P450
M. tuberculosis H37RvRv0766ccyp1232e-3931.64% (373) cytochrome P450 123
M. leprae Br4923MLBr_02088-2e-3731.69% (325) putative cytochrome p450
M. abscessus ATCC 19977MAB_1939-1e-4030.84% (428) cytochrome P450
M. marinum MMMAR_4694cyp150A61e-14256.97% (423) cytochrome P450 150A6 Cyp150A6
M. avium 104MAV_0964-1e-14157.78% (424) cytochrome p450
M. smegmatis MC2 155MSMEG_4780-1e-15061.70% (423) cytochrome p450
M. ulcerans Agy99MUL_0314cyp150A61e-14056.26% (423) cytochrome P450 150A6 Cyp150A6
M. vanbaalenii PYR-1Mvan_4141-1e-14258.41% (428) cytochrome P450

CLUSTAL 2.0.9 multiple sequence alignment


TH_2718|M.thermoresistible__bu      -------------------------------VTDFDTVDFFTDESLVGDP
Mflv_4149|M.gilvum_PYR-GCK          -----------------------MTDHPDADGIDFETVDYFTDAALVPDP
MSMEG_4780|M.smegmatis_MC2_155      -------------------MTDSTATDPAATTPDFDTVDYFTDQSLVPDP
Mvan_4141|M.vanbaalenii_PYR-1       -------------------------------MSDFDTIDYFTDPSLVPDP
MMAR_4694|M.marinum_M               -------------------------------MSSYESIDFFTDPSLIPDP
MUL_0314|M.ulcerans_Agy99           -------------------------------MSSYESIDFFTDPSLIPDP
MAV_0964|M.avium_104                -------------------------------MSNFDSIDFFTDPSLVPDP
Mb0789c|M.bovis_AF2122/97           ---------------------------MTVRVGDPELVLDPYDYDFHEDP
Rv0766c|M.tuberculosis_H37Rv        ---------------------------MTVRVGDPELVLDPYDYDFHEDP
MLBr_02088|M.leprae_Br4923          MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLIDPGTRADP
MAB_1939|M.abscessus_ATCC_1997      -----------------------------------MNTDELFDPQVLEDP
                                                                              *     **

TH_2718|M.thermoresistible__bu      YSYFEHLRSKCPVVEATPHKVLAVTGYEEALEVYRNP-AFSSCVSVAGPF
Mflv_4149|M.gilvum_PYR-GCK          YPYFDHLRSKCPVTQATPFNVLAVTGYTEALSVYKNP-AFSSCNSVAGPF
MSMEG_4780|M.smegmatis_MC2_155      HPYFDHLRSKCPVVREPHYGVLAITSFEEATTVLKDTETFSSCIAVGGPF
Mvan_4141|M.vanbaalenii_PYR-1       HPYFDHLRSKCPVVREPHYGVLAVTGYEEAATVLKDSDTFSSCIAVAGPF
MMAR_4694|M.marinum_M               HPYFDYLRSQSPVLRLPQYGVVAVTGYEEATAVYKDTDSFSNCVALGGPF
MUL_0314|M.ulcerans_Agy99           HPYFDYLRRQSPVLRLPQYGVVAVTGYEEATAVYKDTDSFSNCVALGGPF
MAV_0964|M.avium_104                HPYFDYLRSQNPVLRLPHYGVVAITGYEEATEVYKDPETFSNIVALGGPF
Mb0789c|M.bovis_AF2122/97           YPYYRRLRDEAPLYRNEERNFWAVSRHHDVLQGFRDSTALSNAYGVSLDP
Rv0766c|M.tuberculosis_H37Rv        YPYYRRLRDEAPLYRNEERNFWAVSRHHDVLQGFRDSTALSNAYGVSLDP
MLBr_02088|M.leprae_Br4923          FPVYRALIDYGPMQLPG-MPLTVFSSFSDCDEALRHPLSASDRLKATLAQ
MAB_1939|M.abscessus_ATCC_1997      YPFYRRLRETAPVWPVGDSGFYFVSRWDLVVEATERAEDFSSNLTAALMK
                                    .. :  *    *:       .  .:         . .   *.        

TH_2718|M.thermoresistible__bu      SGMPFGPDGRDDVSDLIEQYRDGVPMAEHITSQDPPLHTRTRGLLNKLIT
Mflv_4149|M.gilvum_PYR-GCK          SGMPFGPGESDDVTDLIEQHRAAVPMAEHITSQDPPLHTRTRGLLSRLIT
MSMEG_4780|M.smegmatis_MC2_155      PPLPFTPEG-DDITGQIEQHRTQLPMFEHMVTMDPPEHTNARSLLNRLLT
Mvan_4141|M.vanbaalenii_PYR-1       PPLPFTPEG-DDITGQIAAHRSQMPMFEHMVTMDPPDHTNARSLLNRLLT
MMAR_4694|M.marinum_M               PPLPFAPNG-DDVNAQIDAHREQFPMYEHMVTMDPPEHSRARSILSRLLT
MUL_0314|M.ulcerans_Agy99           PPLPFTPNG-DDVNAQIDAHREQFPMYEHMVTMDPPEHSRARSILSRLLT
MAV_0964|M.avium_104                PPLPFTPEG-DDISAQIDAHRSSFPMFEHMVTMDPPEHTKARSVLAKLLT
Mb0789c|M.bovis_AF2122/97           SSRTS-----------------EAYRVMSMLAMDDPAHLRMRTLVSKGFT
Rv0766c|M.tuberculosis_H37Rv        SSRTS-----------------EAYRVMSMLAMDDPAHLRMRTLVSKGFT
MLBr_02088|M.leprae_Br4923          QAIAAGAEP-------------RPFYASSFMFLDPPDHTRLRKLVSKAFA
MAB_1939|M.abscessus_ATCC_1997      SAEGLAVAP----------MGPPADPTHVLATGDDPLHHAHRRLVLPTLV
                                                                 :   * * *   * ::   :.

TH_2718|M.thermoresistible__bu      PKRLKENEEFMWRLADQQLDRFLDR---GSAEFLEDYAKPFSLLVIADLL
Mflv_4149|M.gilvum_PYR-GCK          PKRLKENEDFMWRLADRQLDTFIGR---GSAEFLTDYAKPFSLLVIADLL
MSMEG_4780|M.smegmatis_MC2_155      PKRLKENEDFMWRLADECLDDFIDD---GSCEFLKQYAKPFSLLVIADLL
Mvan_4141|M.vanbaalenii_PYR-1       PSRLKENEDFMWRLADEVLDDIISRDPVGRCEFLSAYAKPFSLLVIADML
MMAR_4694|M.marinum_M               PSRLKQNEEFMWRLADRQLDEFLGA---GECEFISEYAKPFATLVIADLL
MUL_0314|M.ulcerans_Agy99           PSRLKQNEEFMWRLADRQLDEFLGA---AECEFISEYAKPFATLVIADLL
MAV_0964|M.avium_104                PSRLKQNEEFMWRLADRQLDEFLHN---GECEFIAEYSKPFATLVIADLL
Mb0789c|M.bovis_AF2122/97           PRRIRELEPQVLELARIHLDSALQT---ESFDFVAEFAGKLPMDVISELI
Rv0766c|M.tuberculosis_H37Rv        PRRIRELEPQVLELARIHLDSALQT---ESFDFVAEFAGKLPMDVISELI
MLBr_02088|M.leprae_Br4923          PKVVQALEGDIAALVDSLLDKGAAA---GQFDVIADLAFPLAVAVICRLL
MAB_1939|M.abscessus_ATCC_1997      ARRITALEPVMAQTGSCLWERGVNG---DGIDWMAAMGDALPMTMVARLI
                                    .  :   *  :        :           : :   .  :.  ::. ::

TH_2718|M.thermoresistible__bu      GVPAADHEEFK-----AAFAL----ETVGELGKDAPTSHNPLEWLNDKFR
Mflv_4149|M.gilvum_PYR-GCK          GVPAEDHEQFK-----AVFAG----ETVGELGKEAPTTHNPLQWLNDKFH
MSMEG_4780|M.smegmatis_MC2_155      GVPEEDHDEFR-----HVLGAPRPGAIVGSLDG-DQLAMNPLAWLDDKFV
Mvan_4141|M.vanbaalenii_PYR-1       GVPEADHEEFR-----TVLGAPRPGANVGSLDHSDLVGANPLEWLDEKFI
MMAR_4694|M.marinum_M               GVPEDDRKDFR-----VVLGADRMG-RVGALDH-ESVGVNPLQWLDDKFS
MUL_0314|M.ulcerans_Agy99           GVPEDDRKDFR-----VVLGADRMG-RVGALDH-ESVGVNPLQWLDDKFS
MAV_0964|M.avium_104                GVPEEDHTQFR-----TVLGADRPGARVGALDH-ETVGINPLEWLDDKFC
Mb0789c|M.bovis_AF2122/97           GVPDTDRARIRALADAVLHRED---GVADVPP----PAMAASIELMRYYA
Rv0766c|M.tuberculosis_H37Rv        GVPDTDRARIRALADAVLHRED---GVADVPP----PAMAASIELMRYYA
MLBr_02088|M.leprae_Br4923          GVPYEDAPEFGRVSALLVQSVDPFITITGEPPEATEERLRAGVWLRDYLE
MAB_1939|M.abscessus_ATCC_1997      GLPAGDVPQLVQWG----YSSTEMLGGLNTPQR-QAQVVTDTMHLVLYLR
                                    *:*  *   :                  .               *     

TH_2718|M.thermoresistible__bu      AYIEDRRRAPRADVLTELAHARYEDGSTPDIDDVMNVSTFLFAAGTETTT
Mflv_4149|M.gilvum_PYR-GCK          AYIEDRRREPRDDVLTELAQAKHEDGSTPDIEDVMNLSTFLFAAGTETTT
MSMEG_4780|M.smegmatis_MC2_155      RYLEDRRKEPRDDVLTALATAKYPDGSTPEVIDVVRSATFLFAAGQETTT
Mvan_4141|M.vanbaalenii_PYR-1       GYLEDRRKEPRDDVLTALATAKYPDGSTPPVIEVVRSATFLFAAGQETTT
MMAR_4694|M.marinum_M               AYIEDRRRQPRNDVLTALATATYPDGSTPEVIDVVRSATFLFAAGQETTA
MUL_0314|M.ulcerans_Agy99           AYIEDRRRRPRNDVLTALATATYPDGSTPEIIDVVRWATFLFAAGQETTA
MAV_0964|M.avium_104                NYIEERRREPRADVLTFLAEAKYPDGSTPPVIEVVRSATFLFAAGQETTA
Mb0789c|M.bovis_AF2122/97           DLIAEFRRRPANNLTSALLAAEL-DGDRLSDQEIMAFLFLMVIAGNETTT
Rv0766c|M.tuberculosis_H37Rv        DLIAEFRRRPANNLTSALLAAEL-DGDRLSDQEIMAFLFLMVIAGNETTT
MLBr_02088|M.leprae_Br4923          QLVKCRRGTPGEDLISRLIELDE-SGDQLTEEEIIATCGLLLVAGHETTV
MAB_1939|M.abscessus_ATCC_1997      EHLEEELAAPGDDLLGYLAQACNRGDISLDIG--VMILVQLVGAGGESTA
                                      :      *  ::   *      ..        :     :. ** *:*.

TH_2718|M.thermoresistible__bu      KLVSFAVRSIAEDQRLQQELRADRSRIPAFLEETLRMESPVKAHFRMART
Mflv_4149|M.gilvum_PYR-GCK          KLVSSAVRFIADNPGYEAMLRRDRSKIPAFLEETLRLESPVKSHFRMAAT
MSMEG_4780|M.smegmatis_MC2_155      KLLSASLRVLGDRPDIQQALREDRSRIPTFVEEALRMDAPVKSQFRLAKK
Mvan_4141|M.vanbaalenii_PYR-1       KLLSASLRVLGDHPDIQERLRRDRSRIPIFVEEALRMDAPVKSQFRLAKK
MMAR_4694|M.marinum_M               KLLTAAMRVLGDRPDIQRRLRENRSLIPNFIEESLRMDSPVKSDSRLARK
MUL_0314|M.ulcerans_Agy99           KQLTAAMRVLGDRPDIQRQLRENRSLIPNFIEESLRMDSPVKSDSRLARK
MAV_0964|M.avium_104                KLLSAALQVLGDRPDIQQQLREDRSLIPAFIEESLRMESPVKSDSRLARR
Mb0789c|M.bovis_AF2122/97           KLLANAVYWAAHHPGQLARVFADHSRIPMWVEETLRYDTSSQILARTVAH
Rv0766c|M.tuberculosis_H37Rv        KLLANAVYWAAHHPGQLARVFADHSRIPMWVEETLRYDTSSQILARTVAH
MLBr_02088|M.leprae_Br4923          NLIANAVLAMLRNPSQWKALSSNPQRAPLVVEETLRYDPAIHLIGRVAAK
MAB_1939|M.abscessus_ATCC_1997      GLMGNAVRILGENPRLQQRIRENRALLPTFLEEALRLESPFRGHHRHVLT
                                      :  ::            :  :    *  :**:** :.. :   * .  

TH_2718|M.thermoresistible__bu      TTTIGDVKVPAGTTIMLLPGACNRDPRKFIDPDSFRPDRPNVREQIAFIR
Mflv_4149|M.gilvum_PYR-GCK          STTIGDVDVPAGTTVMVLPGACNRDARKFADPNSFRPDRQNVREQIAFIR
MSMEG_4780|M.smegmatis_MC2_155      TTQLGGVDVPAGTTLMVCPGAVNRDPVRFEDPHTFSLDRKNVREHIAFGR
Mvan_4141|M.vanbaalenii_PYR-1       NTRVGDMDVPAGTTMMVCPGAVNRDPSRFEHPHEFDLDRKNVREHIAFGR
MMAR_4694|M.marinum_M               RTTVGGLDIAAGTVVMVLPGAANRDPRRFEDPHEFRLDRPNVREHMAFAR
MUL_0314|M.ulcerans_Agy99           RTTVGGLDIAAGTVVMVLSGAANRDPRRFEDPHEFRLDRPNVREHMAFAR
MAV_0964|M.avium_104                ATTIGGVDIPAGTVVMILPGAANRDPRRFENPHEFDLRRKNVREHMAFAR
Mb0789c|M.bovis_AF2122/97           DLTLYDTTIPEGEVLLLLPGSANRDDRVFDDPDDYRIGREIGCKLVSFGS
Rv0766c|M.tuberculosis_H37Rv        DLTLYDTTIPEGEVLLLLPGSANRDDRVFDDPDDYRIGREIGCKLVSFGS
MLBr_02088|M.leprae_Br4923          DMTIGQTTLTEGDTMVLLLAAANRDPAVYSRPDEFDPDRPS-SRHLAFAV
MAB_1939|M.abscessus_ATCC_1997      DTTLGGVQLPAGSHLTLLWGAANRDPAIFEDPDVLRLDRPSPRGHITFGK
                                       :    :. *  : :  .: ***   :  *.     *      ::*  

TH_2718|M.thermoresistible__bu      GPHSCPGAPLARAEGRISLNRILDRMTDIRISQAHHGPAEHRRYTYEPTF
Mflv_4149|M.gilvum_PYR-GCK          GAHSCPGAPLARAEGRISLERILDRMQDITISEDHHGPAGDRRYAYEPTF
MSMEG_4780|M.smegmatis_MC2_155      GVHSCPGGPLARVEGRVSLERILDRMADIRIDEEHHGPADNRRYTYEPTY
Mvan_4141|M.vanbaalenii_PYR-1       GVHSCPGGPLARVEGRVSIERILDRMGDIAIDEELHGPPGARRYNYEPTF
MMAR_4694|M.marinum_M               GVHSCPGGPLARVEGRVSLERILDRMLDIAINEDRHGPADDRRYTYEPTY
MUL_0314|M.ulcerans_Agy99           GVHSCPGGPLARVEGRVSLERILDRMLDIAINEDRHGPADDRRYTYEPTY
MAV_0964|M.avium_104                GVHSCPGGPLARVEGRVSIERILDRMPHIEINETHHGPAGDRRYTYEPTY
Mb0789c|M.bovis_AF2122/97           GAHFCLGAHLARMEARVALGALLRRIRNYEVDDD--------NVVRVHSS
Rv0766c|M.tuberculosis_H37Rv        GAHFCLGAHLARMEARVALGALLRRIRNYEVDDD--------NVVRVHSS
MLBr_02088|M.leprae_Br4923          GSHFCLGAALARLEATVTLSAISARFPQVQLAGE--------LVYKPN-V
MAB_1939|M.abscessus_ATCC_1997      GLHFCVGAALARLEARTAINLLLDRTREFAIKPD--------GAHWVPSI
                                    * * * *. *** *.  ::  :  *  .  :                   

TH_2718|M.thermoresistible__bu      IMRGLNELHIEFSPGS------
Mflv_4149|M.gilvum_PYR-GCK          IMRGLSELHITFTEKEH-----
MSMEG_4780|M.smegmatis_MC2_155      ILRGLTDLHIKFEPVR------
Mvan_4141|M.vanbaalenii_PYR-1       ILRGLTDLNITFTPVR------
MMAR_4694|M.marinum_M               ILRGLTELHITFTPAG------
MUL_0314|M.ulcerans_Agy99           ILRGLTELHITFTPAG------
MAV_0964|M.avium_104                ILRGLSELHLTFTTADAVAPVG
Mb0789c|M.bovis_AF2122/97           NVRGFAHLPISVQAR-------
Rv0766c|M.tuberculosis_H37Rv        NVRGFAHLPISVQAR-------
MLBr_02088|M.leprae_Br4923          AMRGMSALPVQV----------
MAB_1939|M.abscessus_ATCC_1997      MVRRHQKLELEVSAA-------
                                     :*    * : .