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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4112 | - | - | 100% (411) | putative putative acetyl-/propionyl-coenzyme A carboxylase alpha chain |
| M. thermoresistible (build 8) | TH_3591 | - | e-180 | 72.73% (407) | PUTATIVE putative Betaine-aldehyde dehydrogenase |
| M. thermoresistible (build 8) | TH_3068 | - | 1e-90 | 46.44% (379) | PUTATIVE aldehyde dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0791 | aldA | 2e-72 | 42.53% (348) | aldehyde dehydrogenase NAD dependant AldA |
| M. gilvum PYR-GCK | Mflv_0428 | - | 4e-92 | 47.52% (343) | betaine-aldehyde dehydrogenase |
| M. tuberculosis H37Rv | Rv0223c | - | 3e-93 | 42.89% (394) | aldehyde dehydrogenase |
| M. leprae Br4923 | MLBr_02573 | gabD1 | 3e-55 | 35.36% (345) | succinic semialdehyde dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4484 | - | 2e-89 | 43.96% (389) | aldehyde dehydrogenase |
| M. marinum M | MMAR_0472 | - | 3e-89 | 46.04% (341) | aldehyde dehydrogenase |
| M. avium 104 | MAV_4946 | - | 8e-91 | 48.09% (341) | aldehyde dehydrogenase family protein |
| M. smegmatis MC2 155 | MSMEG_0309 | - | 1e-92 | 46.06% (343) | aldehyde dehydrogenase family protein |
| M. ulcerans Agy99 | MUL_1122 | - | 9e-88 | 45.45% (341) | aldehyde dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0240 | - | 2e-94 | 48.69% (343) | betaine-aldehyde dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0472|M.marinum_M -----------MGEKTEYDKLFIGGKWTEPSTSEVIEVHCPATGEYVGKV
MUL_1122|M.ulcerans_Agy99 -----------MGEKTEYDKLFIGGRWTEPSTSEVIEVHCPATGEYVGKV
MAV_4946|M.avium_104 ------MSDIQTQAKTEYDKLFIGGKWTEPSTSEVIEVHCPATGEYVGKV
Rv0223c|M.tuberculosis_H37Rv ----------MSDSATEYDKLFIGGKWTKPSTSDVIEVRCPATGEYVGKV
MAB_4484|M.abscessus_ATCC_1997 --------------MTNYDKLFIGGVWTEPATDQVIEVISPATGQKVGQC
Mflv_0428|M.gilvum_PYR-GCK ---MTQS----TAFRTEWDKLFIGGKWVEPASSEVIEVRSPATGDVVGKV
Mvan_0240|M.vanbaalenii_PYR-1 ---MTQS----TTFRTEWDKLFIGGKWVEPATSDVIEVHSPATGELVGKV
MSMEG_0309|M.smegmatis_MC2_155 MTAMTQTAPAATAATTNWDKLFIGGQWVEPSSSEIIEVFSPATGEKVGQA
TH_4112|M.thermoresistible__bu --------------------------------------------------
Mb0791|M.bovis_AF2122/97 ----------MALWGDGISALLIDGKLSD-GRAGTFPTVNPATEEVLGVA
MLBr_02573|M.leprae_Br4923 ---------------------------------MSIATINPATGETVKTF
MMAR_0472|M.marinum_M PLAAAADVDAAVAAARAAFDNGPWPSTPPKERATVIANALKLLEERKDHF
MUL_1122|M.ulcerans_Agy99 PLAAAADVDAAVAAARAAFDNGPWPSTPPKERATVIANALKLLEERKDHF
MAV_4946|M.avium_104 PLAAAADVDAAVAAARAAFDNGPWPTTPPKERAAVIANALKVMEERKDLF
Rv0223c|M.tuberculosis_H37Rv PMAAAADVDAAVAAARAAFDNGPWPSTPPHERAAVIAAAVKMLAERKDLF
MAB_4484|M.abscessus_ATCC_1997 PLASPADVDAAVSAARRAFDNGPWPRLTPHERQAVLQKAVSLLESRKDEI
Mflv_0428|M.gilvum_PYR-GCK PLASAADVDAACAAAREAFDNGPWPQMSPTERAEVLGRAVKLMEERADEL
Mvan_0240|M.vanbaalenii_PYR-1 PLASAADVDAACAAAREAFDNGPWPHMSPAERGEILGRAVKIMEERADEL
MSMEG_0309|M.smegmatis_MC2_155 PLATKADVDAACAAARKAFDEGPWPRMTPQEREAVLAKATALIEESADEF
TH_4112|M.thermoresistible__bu ------------VAPTLHWNYN-----------AVIGRQYPFTEVRTADL
Mb0791|M.bovis_AF2122/97 ADADAEDMGRAIEAARRAFDSTDWSRN-TELRVRCVRQLRDAMQQHVEEL
MLBr_02573|M.leprae_Br4923 TPTTQDEVEDAIARAYARFDNYR--HTTFTQRAKWANATADLLEAEANQS
. ::
MMAR_0472|M.marinum_M AKLLADETGQPPMTVETMHWMGSIGALNFFAGPAVDQVRWKEIRNGSYGQ
MUL_1122|M.ulcerans_Agy99 AKLFADETGQPPMTVETMHWMGSIGALNFFAGPAVDQVRWKEIRNGSYGQ
MAV_4946|M.avium_104 TGLLAAETGQPPTSVETMHWMSSIGALNFFAGPAVDQVKWKEVRTGGYGQ
Rv0223c|M.tuberculosis_H37Rv TKLLAAETGQPPTIIETMHWMGSMGAMNYFAG-AADKVTWTETRTGSYGQ
MAB_4484|M.abscessus_ATCC_1997 CKAIADETGAPPMVIETLQWMGGFGAIQYYAN-AADAVKWKELRNGAYGQ
Mflv_0428|M.gilvum_PYR-GCK KFLLAAETGQPPTIVDMMQYGAAMSSFQFYAG-AADKFTWQDIRDGVYGQ
Mvan_0240|M.vanbaalenii_PYR-1 KFLLAAETGQPPTIVDMMQYGAAMSSFQFYAG-AADKFTWQDIRDGVYGQ
MSMEG_0309|M.smegmatis_MC2_155 KTLLKLETGQPQTIVDMMQYGAAMSTLQFYAS-AADKFAWKDIRDGIYGQ
TH_4112|M.thermoresistible__bu GPLAGGAAG---------------GMVMPFQT-----------------Q
Mb0791|M.bovis_AF2122/97 RELTISEVGAPRMLTASAQLEGPVGDLSFAAD-TAESYPWKQDLGEASPL
MLBr_02573|M.leprae_Br4923 AALMTLEMGKTLQSAKDEAMKCAKGFRYYAEKAETLLADEPAEAAAVGAS
* .
MMAR_0472|M.marinum_M TIVHR-----EPIGVVGAIVAWNVPLFLAINKLGPALLAGCTVVLKPAAE
MUL_1122|M.ulcerans_Agy99 TIVHR-----EPIGVVGAIVAWNVPLFLAINKLGPAPLAGCTVVLKPAAE
MAV_4946|M.avium_104 SIVHR-----EPIGVVGAIVAWNVPLFLAVNKLGPALLAGCTVVLKPAAE
Rv0223c|M.tuberculosis_H37Rv SIVSR-----EPVGVVGAIVAWNVPLFLAVNKIAPALLAGCTIVLKPAAE
MAB_4484|M.abscessus_ATCC_1997 TLVTR-----EPAGVVAAIAAWNVPLFLALNKIGPAFLAGCAVVLKPAAE
Mflv_0428|M.gilvum_PYR-GCK TLVVR-----EPVGVVGAVTAWNVPFFLAANKLGPALLAGCTVVLKPAAE
Mvan_0240|M.vanbaalenii_PYR-1 TLVVR-----EPVGVVGAVTAWNVPFFLAANKLGPALLAGCTVVLKPAAE
MSMEG_0309|M.smegmatis_MC2_155 TLVLK-----EPVGVVGAVVAWNVPFFLAANKLGPALLAGCTIVLKPAAE
TH_4112|M.thermoresistible__bu SLTVK-----EPAGVLAALVAYNFSLAGTAQKVAPAIVAGCTVVIKVPEP
Mb0791|M.bovis_AF2122/97 GIATRRTLAREAVGVVGAITPWNFPHQINLAKLGPALAAGNTVVLKPAPD
MLBr_02573|M.leprae_Br4923 KALAR----YQPLGVVLAVMPWNFPLWQTVRFAAPALMAGNVGLLKHASN
: :. **: *: .:*.. .** ** . ::* .
MMAR_0472|M.marinum_M TPLTANALAEVFAEAG-LPEGVLSVVPGG-VETGQALTSNPGVDLFTFTG
MUL_1122|M.ulcerans_Agy99 TPLTANALAEVFAEAG-LPEGVLSVVPGG-VETGQALTSNPGVDLFTFTG
MAV_4946|M.avium_104 TPLSANALAEAFAEAG-LPEGVLSVVPGG-IETGQALTSNTDVDIFSFTG
Rv0223c|M.tuberculosis_H37Rv TPLTANALAEVFAEVG-LPEGVLSVVPGG-IETGQALTSNPDIDMFTFTG
MAB_4484|M.abscessus_ATCC_1997 TPLSSFILAEVFAEAG-VPEGVLSVVPGG-AETGRALTNNPDVDVFSFTG
Mflv_0428|M.gilvum_PYR-GCK TPLSVFAMAEMFVEAG-LPEGVLSIVPGG-PETGQALTANPNLDKYTFTG
Mvan_0240|M.vanbaalenii_PYR-1 TPLSVFAMAEMFVEAG-LPEGVLSIVPGG-PETGQALTANPNLDKYTFTG
MSMEG_0309|M.smegmatis_MC2_155 TPLTTNLMAQKFLEAG-LPEGVLSVVPGG-PETGRALTDNPALDKFTFTG
TH_4112|M.thermoresistible__bu NPLAVFAMGELIQEVG-FPPGVINIVAAG-PEVSHHLVTHEGVDMVSFTG
Mb0791|M.bovis_AF2122/97 TPWCAAALGEIIVEHTDFPPGVVNIVTSSSHALGALLAKDPRVDMISFTG
MLBr_02573|M.leprae_Br4923 VPQCALYLADVIARGG-FPEDCFQTLLIS-ANGVEAILRDPRVAAATLTG
* :.: : . .* . .. : . : . : ::**
MMAR_0472|M.marinum_M SSAVGKEIGRRAAEMLKPCTLELGGKSAAILLEDVDLSTAVPMMVFSGIM
MUL_1122|M.ulcerans_Agy99 SSAVGKEIGRRAAEMLKPCTLELGGKSAAILLEDVDLSTAVPMMVFSGIM
MAV_4946|M.avium_104 SSAVGREIGRRAADMLKPCTLELGGKSAAIVLDDVDLPSALPMLVFSGIM
Rv0223c|M.tuberculosis_H37Rv SSAVGREVGRRAAEMLKPCTLELGGKSAAIILEDVDLAAAIPMMVFSGVM
MAB_4484|M.abscessus_ATCC_1997 STAVGKEIAEIAAKNLKKVTLELGGKSAAIVLEDADLAAALPMLVFSGLM
Mflv_0428|M.gilvum_PYR-GCK SSGVGKEIAKIAADKLKPCTLELGGKSAAIILEDADLDSTLPMLVFSGLM
Mvan_0240|M.vanbaalenii_PYR-1 SSGVGKEIAKIAADKLKPCTLELGGKSAAIILEDADLDSTLPMLVFSGLM
MSMEG_0309|M.smegmatis_MC2_155 SSAVGKEIGKIAAEKLKPCTLELGGKSAAIILEDADLDSTLPMLLFSGLM
TH_4112|M.thermoresistible__bu SRAVGEQIGAACGALVRPAVLELGGKASAIVLDDADLDDVIPTLVAVSVV
Mb0791|M.bovis_AF2122/97 STATGRAVMADAAATIKKVFLELGGKSAFVVLDDADLAAASAVSAFSACM
MLBr_02573|M.leprae_Br4923 SEPAGQAVGAIAGNEIKPTVLELGGSDPFIVMPSADLDAAVATAVTGRVQ
* .*. : .. :: *****. . ::: ..** . .
MMAR_0472|M.marinum_M NT-GQACVGQTRILAPRSRYEEIVEAVSAFVQALPVGPPSDPAAQIGSLI
MUL_1122|M.ulcerans_Agy99 NT-GQACVGQTRILAPRSRYEEIVEAVSAFVQTLPVGPPSDPAAQIGSLI
MAV_4946|M.avium_104 NS-GQACVAQTRILAPRSRYDEIVDAVSTFVQSLPVGLPSDPAAQIGSLI
Rv0223c|M.tuberculosis_H37Rv NA-GQGCVNQTRILAPRSRYDEIVAAVTNFVTALPVGPPSDPAAQIGPLI
MAB_4484|M.abscessus_ATCC_1997 NA-GQGCVNQTRVLAPRSRYDEVVDGIVGMVSLMGVGLPDDPATQVGPLI
Mflv_0428|M.gilvum_PYR-GCK NS-GQACVGQTRILAPRSRYDEVIEKLGEAVRNMAPGLPDNPAAMIGPLI
Mvan_0240|M.vanbaalenii_PYR-1 NS-GQACVGQTRILAPRSRYDEVVEKLAAAAAGMAPGLPDNPAAMIGPLI
MSMEG_0309|M.smegmatis_MC2_155 NS-GQACVGQTRILAPRSRYDEVVEKVAAGVAAMQVGVPDDPAAMVGPLI
TH_4112|M.thermoresistible__bu PSSGQSCTSQSRFLVPRARHDEIVDRLVRAFGDLKVGDPHDPDTQIGPMI
Mb0791|M.bovis_AF2122/97 HA-GQGCAITTRLVVPRARYEEAVAIAAATMSSIRPGDPNDPGTVCGPLI
MLBr_02573|M.leprae_Br4923 NN-GQSCIAAKRFIAHADIYDEFVEKFVARMETLRVGDPTDPDTDVGPLA
**.* .*.:. ::* : : * * :* : *.:
MMAR_0472|M.marinum_M SEKQRARVEGYIAKGIEEGARLVSGGGRPEGLDNGFFVQPTVFADVDNKM
MUL_1122|M.ulcerans_Agy99 SEKQRARVEGYIAKGIEEGARLVSGGGRPESLDNGFFVQPTVFADVDNKM
MAV_4946|M.avium_104 SEKQRARVEGYIAKGIEEGARLVCGGGRPEGLDSGFFVQPTVFADVDNKM
Rv0223c|M.tuberculosis_H37Rv SEKQRTRVEGYIAKGIEEGARLVCGGGRPEGLDNGFFIQPTVFADVDNKM
MAB_4484|M.abscessus_ATCC_1997 TEKQRTRVEGYIAKGIAEGARLAYGGKRPEGLDGGYFVQPTIFADVDNSM
Mflv_0428|M.gilvum_PYR-GCK SEKQRDRVEGYIKKGIEEGARVITGGGRPEGLDSGWFVEPTVFADVDNSM
Mvan_0240|M.vanbaalenii_PYR-1 SEKQRDRVEGYIKKGIEEGARVVTGGGRPEGLDSGWYVQPTVFADVDNSM
MSMEG_0309|M.smegmatis_MC2_155 SEKQRERVEGYIKKGIEEGARLVTGGGRPEGLDSGWFVQPTVFADVDNSM
TH_4112|M.thermoresistible__bu TRAHQQRVLGFIERAVRDGATIAFGGGVPDGLDRGWYVQPTLMTGVTPEM
Mb0791|M.bovis_AF2122/97 SARQRDRVQGYLDLAVAEGGRFACGGARPADREVGFYIEPTVIAGLTNDA
MLBr_02573|M.leprae_Br4923 TESGRAQVEQQVDAAAAAGAVIRCGGKRPD--RPGWFYPPTVITDITKDM
: : :* : . *. . ** * *:: **:::.: .
MMAR_0472|M.marinum_M TIAQEEIFGPVLVVIPYDTEEDAIKIANDSVYGLAGSVWTSNVPKGIEIS
MUL_1122|M.ulcerans_Agy99 TIAQEEIFGPVLVVIPYDTKEDAIKIANDSVYGLAGSVWTSNVPKGIEIS
MAV_4946|M.avium_104 TIAQEEIFGPVLSIIPYDTEEDAIKIANDSVYGLAGSVWTADVQRGIAVS
Rv0223c|M.tuberculosis_H37Rv TIAQEEIFGPVLAIIPYDTEEDAIAIANDSVYGLAGSVWTTDVPKGIKIS
MAB_4484|M.abscessus_ATCC_1997 TIAQEEIFGPVLSIIAYDSVDEAVKIANDSNYGLAGSVWTTDVQKGLEVA
Mflv_0428|M.gilvum_PYR-GCK TIAQEEIFGPVLSVIPYEDEDDAVRIANDSVYGLAGSVYTTDNDRALKIA
Mvan_0240|M.vanbaalenii_PYR-1 TIAQEEIFGPVLAVIPYEDEDDAVRIANDSVYGLAGSVYTTDNDRALKIA
MSMEG_0309|M.smegmatis_MC2_155 TIAQEEIFGPVLVVIPFEDEDDAVRIANDSVYGLAGSVYTTDHAKGVEIA
TH_4112|M.thermoresistible__bu EIAQEEVFGPVAVVIPYDTEDQAIEIANNTPYGLSGSVFTADVAHGFRLA
Mb0791|M.bovis_AF2122/97 RVAREEIFGPVLTVIAHDGDDDAVRIANDSPYGLSGTVYGADPQRAARIA
MLBr_02573|M.leprae_Br4923 ALYTDEVFGPVASVYCATNIDDAIEIANATPFGLGSNAWTQNESEQRHFI
: :*:**** : ::*: *** : :**....: : . .
MMAR_0472|M.marinum_M EKIRTGTYAIN---WYAFDPCCPFGGYKNSGIGRENGPEGVEHFTQQKSV
MUL_1122|M.ulcerans_Agy99 EKIRTGTYAIN---WYAFDPCCPFGGYKNSGIGRENGPEGVEHFTQQKSV
MAV_4946|M.avium_104 EKIRTGTYAIN---WYAFDPCCPFGGYKNSGIGRENGPEGVEHFTQQKSV
Rv0223c|M.tuberculosis_H37Rv QQIRTGTYGIN---WYAFDPGSPFGGYKNSGIGRENGPEGVEHFTQQKSV
MAB_4484|M.abscessus_ATCC_1997 AQIRTGTYGIN---WYAFDPSCPFGGYKQSGIGRENGPEGIEEYCELKSV
Mflv_0428|M.gilvum_PYR-GCK RRIRTGTYAVN---MYAFDPCAPFGGYKNSGIGRENGWEGIEAYCEQKSI
Mvan_0240|M.vanbaalenii_PYR-1 RRIRTGTYAVN---MYAFDPCAPFGGFKNSGIGRENGWEGIEAYCEPKSI
MSMEG_0309|M.smegmatis_MC2_155 SKVRTGTYGIN---MYAFDPGAPFGGYKNSGIGRECGPEGIAGYCESKSV
TH_4112|M.thermoresistible__bu RRIHTGTFAVN---SYTADFNAPFGGVKRSGIGREHGPAGLAEYLRPKTI
Mb0791|M.bovis_AF2122/97 SRLRVGTVNVNGGVWYCAD--APFGGYKQSGIGREMGLLGFEEYLEAKLI
MLBr_02573|M.leprae_Br4923 DNIVAGQVFING--MTVSYPELPFGGIKRSGYGRELSTHGIREFCNIKTV
.: .* :* **** *.** *** . *. : . * :
MMAR_0472|M.marinum_M LMPMGYTLES---------------
MUL_1122|M.ulcerans_Agy99 LMPMGYTLES---------------
MAV_4946|M.avium_104 LMPMGYTLEG---------------
Rv0223c|M.tuberculosis_H37Rv LLPMGYTVA----------------
MAB_4484|M.abscessus_ATCC_1997 LLPMGYTLESI--------------
Mflv_0428|M.gilvum_PYR-GCK LLPFGYTPPAS--------------
Mvan_0240|M.vanbaalenii_PYR-1 LLPFGYTPAT---------------
MSMEG_0309|M.smegmatis_MC2_155 LLPFGYTPE----------------
TH_4112|M.thermoresistible__bu AIDPSLELPREVVESADVVTHGVRP
Mb0791|M.bovis_AF2122/97 ATAAN--------------------
MLBr_02573|M.leprae_Br4923 WIA----------------------