For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2946 | - | - | 100% (571) | 3-ketosteroid-delta-1-dehydrogenase |
| M. thermoresistible (build 8) | TH_0368 | - | e-122 | 45.03% (533) | PROBABLE DEHYDROGENASE |
| M. thermoresistible (build 8) | TH_4337 | - | e-116 | 42.91% (571) | PUTATIVE fumarate reductase/succinate dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3567 | - | 1e-126 | 44.58% (563) | 3-ketosteroid-delta-1-dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4567 | - | 0.0 | 68.32% (546) | 3-ketosteroid-delta-1-dehydrogenase |
| M. tuberculosis H37Rv | Rv3537 | - | 1e-126 | 44.58% (563) | 3-ketosteroid-delta-1-dehydrogenase |
| M. leprae Br4923 | MLBr_01226 | nadB | 3e-05 | 39.71% (68) | L-aspartate oxidase |
| M. abscessus ATCC 19977 | MAB_0081 | - | 0.0 | 66.67% (558) | 3-ketosteroid-delta-1-dehydrogenase |
| M. marinum M | MMAR_5024 | - | 1e-124 | 43.79% (564) | dehydrogenase |
| M. avium 104 | MAV_3039 | - | 0.0 | 68.32% (546) | 3-ketosteroid-delta-1-dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_2869 | - | 0.0 | 80.58% (556) | 3-ketosteroid-delta-1-dehydrogenase |
| M. ulcerans Agy99 | MUL_4098 | - | 1e-124 | 43.97% (564) | 3-ketosteroid-delta-1-dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_2868 | - | 0.0 | 76.62% (556) | 3-ketosteroid-delta-1-dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3567|M.bovis_AF2122/97 ---------------MTVQEFDVVVVGSGAAGMVAALVAAHRGLSTVVVE
Rv3537|M.tuberculosis_H37Rv ---------------MTVQEFDVVVVGSGAAGMVAALVAAHRGLSTVVVE
MMAR_5024|M.marinum_M ------------MFYMTSQDYDVVVVGSGGAGMVAALAAAHKGLSTVVIE
MUL_4098|M.ulcerans_Agy99 ---------------MTSQDYDVVVVGSGGAGMVAALAAAHKGLSTVVIE
MSMEG_2869|M.smegmatis_MC2_155 ------------MTDPQNLTVDLLVVGSG-TGMAAALAAHELGLSAMIVE
Mvan_2868|M.vanbaalenii_PYR-1 ------------MTDPQNITVDLLVVGSG-TGMAAALAARELGLSTLIVE
TH_2946|M.thermoresistible__bu MTARRGGGQNRAVTVAQNIEVDLLVVGSG-TGMAAALAAHELGLTTLIVE
Mflv_4567|M.gilvum_PYR-GCK --MTAASATIPAGLPVSDTTVDLLVVGSG-TGMSAALAAHEAGLSVLIVE
MAV_3039|M.avium_104 --MTTHSATIPAGLPVADTAVDLLVVGSG-TGMAAALAAHELGLSVLIVE
MAB_0081|M.abscessus_ATCC_1997 -MASAPPGLIPAGTVAGDIEIDLLIVGAG-TGMAAALAASELGLSVLIVE
MLBr_01226|M.leprae_Br4923 ----------MMAVPDWKHAADVVVIGTGVAGLAAALAAHRAGRNVVVLT
*::::*:* :*: ***.* . * ..:::
Mb3567|M.bovis_AF2122/97 KAPHYGGSTARSGGGVWIPNNEVLKRRGVRDTPEAARTYLHGIVG----E
Rv3537|M.tuberculosis_H37Rv KAPHYGGSTARSGGGVWIPNNEVLKRRGVRDTPEAARTYLHGIVG----E
MMAR_5024|M.marinum_M KAAHYGGSTARSGGGVWIPNNQILKRARVSDTTEAARTYLHGIIGDSSVS
MUL_4098|M.ulcerans_Agy99 KAAHYGGSTARSGGGVWIPNNQILKRARVSDTTEAARTYLHGIIGDSSVS
MSMEG_2869|M.smegmatis_MC2_155 KTALVGGSTARSGGAFWMPANPILSEEGSDDTLDAGRTYLETLVAD----
Mvan_2868|M.vanbaalenii_PYR-1 KTSYVGGSTARSGGAFWMPGNPILTEAGSADSLDKGRTYLDALVGS----
TH_2946|M.thermoresistible__bu KTAQVGGSTARSGGAFWMPANPVLTEAGAADTLDAARSYLEAVVED----
Mflv_4567|M.gilvum_PYR-GCK KSEYVGGSTARSGGALWLPASPVLGAAGAGDSVERARTYLDAVVDG----
MAV_3039|M.avium_104 KSSYVGGSTARSGGALWLPASPVLDEANAGDTAERAGTYLDSVVAG----
MAB_0081|M.abscessus_ATCC_1997 KSHQVGGSTARSGGALWLPASPVLRAAGTGDSVERARTYLRSVVAG----
MLBr_01226|M.leprae_Br4923 KADQRRGETAT----HYAQGGIAVVLPGSDDSVDAHASDTLAAGAG----
*: *.** : . : *: : :
Mb3567|M.bovis_AF2122/97 IVEPERIDAYLDRGPEMLSFVLKHTP-----LKMCWVPGYSDYYPEAPGG
Rv3537|M.tuberculosis_H37Rv IVEPERIDAYLDRGPEMLSFVLKHTP-----LKMCWVPGYSDYYPEAPGG
MMAR_5024|M.marinum_M GVEPERIDTYLERGPEMLSFVLEHTP-----LKMCWVPGYSDYYPEAPGG
MUL_4098|M.ulcerans_Agy99 GVEPERIDTYLERGPEMLSFVLEHTP-----LKMCWVPGYSDYYSEAPGG
MSMEG_2869|M.smegmatis_MC2_155 AAPADRAGAFLDHGSATVEMLRRTTP-----MKFQWAKGYSDYHPERPGG
Mvan_2868|M.vanbaalenii_PYR-1 DAPLERAHAFLENGPATIAMLRRTTP-----MKFQWAKGYSDYHPEQPGG
TH_2946|M.thermoresistible__bu SAPADRWQAFLDHGAETVRMLRRTTP-----MRFQWAKGYSDYHPERPGG
Mflv_4567|M.gilvum_PYR-GCK AAPSERSAGFLAHLTGTLDMLRRTTP-----MKLFWAREYSDYHPEQPGG
MAV_3039|M.avium_104 SAPPQRSAAFVAQVSATVEMLRRTTP-----LRLFWARDYSDYHPEEPGG
MAB_0081|M.abscessus_ATCC_1997 SAPDARSDAFLEHEAATVDMLTRLTP-----MRFTWCRDYADYHPEEPGG
MLBr_01226|M.leprae_Br4923 MCNLDTVYSIVAEGYHAVTELVGYGARFDESIPGRWAVTCEGGHSRRRIV
: . : : . : * . :..
Mb3567|M.bovis_AF2122/97 RPGGRSIEPKPFNARKLGADMAGLEPAYGKV-PLNVVVMQQDYVRLNQLK
Rv3537|M.tuberculosis_H37Rv RPGGRSIEPKPFNARKLGADMAGLEPAYGKV-PLNVVVMQQDYVRLNQLK
MMAR_5024|M.marinum_M RSGGRSIEPKPFDARKLGADMAELEPAYGKI-PLNVVVMQQDYVRLNQLK
MUL_4098|M.ulcerans_Agy99 RSGGRSIEPKPFDARKLGADMAELEPAYGKI-PLNVVVMQQDYVRLNQLK
MSMEG_2869|M.smegmatis_MC2_155 SAVGRTCECRPFDTAVLGRELSRLRPGVMKS-SFPMPVTGADYRWLNLMA
Mvan_2868|M.vanbaalenii_PYR-1 SAVGRTCECRPFDTAVLGSELSRLRPGVMKS-SFPMPVTGADYRWLNLMA
TH_2946|M.thermoresistible__bu AVLGRTCECRPFDARILGPELDRLRPGVMKS-SLPVPVTGADYRWLNLMT
Mflv_4567|M.gilvum_PYR-GCK SAAGRTCECRPLDTAVLGEYLPRLRPGVMEV-TIPMPTTGADYRWLNLMT
MAV_3039|M.avium_104 SAAGRTCECRPFDTSLLGEYRTRLEPGLMEV-TVPMPTTGADYRWMNLVA
MAB_0081|M.abscessus_ATCC_1997 SPTGRTCECRPFDASVLGEYRTRLQPGVMKPPAVPMPVTSADYRWMNLMA
MLBr_01226|M.leprae_Br4923 HAGGDATGAEVQRALDHAADVLDIRTSHLALRVLHDGTVVNGVSVLNPNG
* : . : . :... . . . :*
Mb3567|M.bovis_AF2122/97 RHPR-GVLRSMKVGARTMWAKATGKNLVGMGRALIGPLRIGLQRAGVPVE
Rv3537|M.tuberculosis_H37Rv RHPR-GVLRSMKVGARTMWAKATGKNLVGMGRALIGPLRIGLQRAGVPVE
MMAR_5024|M.marinum_M RHPR-GVLRSMKVGARTMWAKATGKNLVGMGRALIGPLRIGLQRKGVPVQ
MUL_4098|M.ulcerans_Agy99 RHPR-GVLRSMKVGARTMWAKATGKNLVGMGRALIGPLRIGLQRKGVPVQ
MSMEG_2869|M.smegmatis_MC2_155 RVPRKAVPRIMLRAFQGIGGLALRRRYAAGGQALAAGLYAGVLRAGIPVW
Mvan_2868|M.vanbaalenii_PYR-1 RAPRKSWPRIMLRAAQGIGGLALRRRYAAGGQALAAGLFAGVLDAGIPVW
TH_2946|M.thermoresistible__bu RMPLKAIPRIGLRVVQGVGGLALRRRYVAGGQALAAGLFAGVIRAGIPVW
Mflv_4567|M.gilvum_PYR-GCK RVPRKGLPTIAKRLGQGVGGLLLGRRYAAGGQALAAGLFAGVLRAGIPVW
MAV_3039|M.avium_104 RLPRKGIPVYAKRLVQGVGGRMLGRRYAAGGQGLMAGLFTGVLRAGIPIW
MAB_0081|M.abscessus_ATCC_1997 RLPRKALPLIVKRIAQGVGGAVLGRRYLAGGQALAAGLFAGVLRAGIPIW
MLBr_01226|M.leprae_Br4923 WGIVSAPSVILASGGLGHLYGATTNPEGSTGDGIALALWAGVAVSDLEFI
. . . * .: * *: .: .
Mb3567|M.bovis_AF2122/97 LNTAFTDLFVENGVVSGVYVRDSHEAESAEPQLIRARRGVILACGGFEHN
Rv3537|M.tuberculosis_H37Rv LNTAFTDLFVENGVVSGVYVRDSHEAESAEPQLIRARRGVILACGGFEHN
MMAR_5024|M.marinum_M LNTALTDLYLEDGMVRGIYVRSTDAQESEEPQLIRARKGVILACGGFDHN
MUL_4098|M.ulcerans_Agy99 LNTALTDLYLEDGVVRGIYVRSTDAHESEEPQLIRARKGVILACGGFDHN
MSMEG_2869|M.smegmatis_MC2_155 TQSPLVRLLVDGDRVTGAVVNRNGIDVA-----ITARRGVVLATGGFDHQ
Mvan_2868|M.vanbaalenii_PYR-1 TDSPVTTLVTDGARVTGAVVDRNGTEVT-----VTARRGVVLAAGGFDRL
TH_2946|M.thermoresistible__bu THSPLTRLLFDGDDVVGAVIDRHGAEVT-----VRTRRGVILATGGFDHL
Mflv_4567|M.gilvum_PYR-GCK TDTALVELTGDDARVTGAVVSHRGTEIT-----VTARRGVVLAAGGFDHN
MAV_3039|M.avium_104 TGTTLTRLTRRGERVSGAVVEHGGREVT-----ISARRGVVLATGGFDHR
MAB_0081|M.abscessus_ATCC_1997 TGTSLVRLTTAGGRVTGAVVALAGREFT-----VTVSRGVVLAAGGFDHD
MLBr_01226|M.leprae_Br4923 QFHPTMLFAAGTG--TGGRRPLVTEAIRGEGAILLDSKGNSVTSGVHPLG
. : * : :* :: * .
Mb3567|M.bovis_AF2122/97 EQMRIKYQRAPITTEWTVGASANTGDGILAAEKLGAALDLMDDAWWGPTV
Rv3537|M.tuberculosis_H37Rv EQMRIKYQRAPITTEWTVGASANTGDGILAAEKLGAALDLMDDAWWGPTV
MMAR_5024|M.marinum_M EQMRVKYQRAPITTDWTVGAKANTGDGIVAAEKLGAALDLMEDAWWGPTV
MUL_4098|M.ulcerans_Agy99 EQMRVKYQRAPITTDWTVGAKANTGDGIVAAEKLGAALDLMEDAWWGPTV
MSMEG_2869|M.smegmatis_MC2_155 MDWRRKFQSESMNEDLSLGSEGNTGDGIRIAQDLGADTGLMDQAWWFPAF
Mvan_2868|M.vanbaalenii_PYR-1 MSWRHKFQSELLGDHHSLGAEGNTGDGIRMAQDLGAGTGLMDQAWWFPAF
TH_2946|M.thermoresistible__bu LDWRRKFQLESLPGDLSLGAEGNTGDGIRIAQEVGAGTGLMDQAWWFPAF
Mflv_4567|M.gilvum_PYR-GCK MDMRWKFQSESLQPGVSLGADTNTGDAIRIAQDRGAAIGLMDQSWWFPAV
MAV_3039|M.avium_104 MEMRWKFQSESLGADLSLGAAGNTGDGIRAGQEIGAAIDLMDQAWWFPAV
MAB_0081|M.abscessus_ATCC_1997 MEMRHKFQSAALGENMSLGADTNTGDALRIGQDCGAAIDSMNQAWWFPAV
MLBr_01226|M.leprae_Br4923 DLAPRDVVAAAIDARLKATGDSCVYLDARGIDGFASRFPTVTAACRTVGI
. : . . . : .: : : .
Mb3567|M.bovis_AF2122/97 P-LVG-KPWFALSERNSPGSIIVNMSGKRFMNESMPYVEACHHMYGGEHG
Rv3537|M.tuberculosis_H37Rv P-LVG-KPWFALSERNSPGSIIVNMSGKRFMNESMPYVEACHHMYGGEHG
MMAR_5024|M.marinum_M P-LVG-RPWFALSERNSPGSIIVNMSGQRFMNESMPYVEACHHMYGGQYG
MUL_4098|M.ulcerans_Agy99 P-LVG-RPWFALSERNSPGSIIVNMSGQRFMNESMPYVEACHHMYGGQYG
MSMEG_2869|M.smegmatis_MC2_155 APLPGGEPTVMLAERSLPGCLLVDQTGNRFINEATDYMSFGQRVLDRERV
Mvan_2868|M.vanbaalenii_PYR-1 APLPGGDPTVMLAERSLPGCLLVDQKGERFINEATDYMSFGQQLLQREQA
TH_2946|M.thermoresistible__bu APLPGGEPAVMLAERSLPGCLLVDQTGNRFINEATDYMSFGQQLLRRERS
Mflv_4567|M.gilvum_PYR-GCK APLPGKAPAVMLAERSLPGSLIVDQNGRRFANESSDYMSFGQRVLELERT
MAV_3039|M.avium_104 APLPGKAPAVMLAERSLPGCLIVDQHGRRFVNEATDYMSFGQRLLELERS
MAB_0081|M.abscessus_ATCC_1997 APLPGGAPKVMLAERSLPGSFIVDHTGNRFINEATDYMSFGQRVLERERS
MLBr_01226|M.leprae_Br4923 DPAREPIPVVPGAHYSCGG-IVTDAYG---QTELAGLFAAGEVARTGMHG
* . :. . * ::.: * .* . .
Mb3567|M.bovis_AF2122/97 QGPGPGENIPAWLVFDQRYRDRYIFAG-LQPGQRIPSRWLDSGVIVQADT
Rv3537|M.tuberculosis_H37Rv QGPGPGENIPAWLVFDQRYRDRYIFAG-LQPGQRIPSRWLDSGVIVQADT
MMAR_5024|M.marinum_M QGPGPGENIPAWLVFDQRYRDRYIFAG-LQPGQRIPRKWLDSGVIVMADT
MUL_4098|M.ulcerans_Agy99 QGPGPGENIPAWLVFDQRYRDRYIFAG-LQPGQRIPRKWLDSGVIVMADT
MSMEG_2869|M.smegmatis_MC2_155 GNP----VDVMWMIFDQRYRNSYLLATELFPRMPIPQTWYDAGIAHRSDD
Mvan_2868|M.vanbaalenii_PYR-1 GDP----VEVMWMIFDQRYRNSYLLAAELFPRMPIPQAWFDAGIAYRSTD
TH_2946|M.thermoresistible__bu GHP----VEDMWMVFDQRYRDSYLLAAELFPRMPLPRSWYDAGIAHRSDD
Mflv_4567|M.gilvum_PYR-GCK GTP----VESMWIVFDQKYRNSYVFAAELFPRMAIPQSWYDAGIAHRADD
MAV_3039|M.avium_104 GSP----VESMWIVFDQQYRNSYVFGAELFPRMRIPQAWYDAGIAVRADN
MAB_0081|M.abscessus_ATCC_1997 GDP----AESMWIIFDQQYRNSYVFAGQLYPRMPVPVSWFEARIAYRADS
MLBr_01226|M.leprae_Br4923 ANR----------LASNSLLEGLVVGG-------------RAGRAAAAHA
: .: : :.. : :
Mb3567|M.bovis_AF2122/97 LAELAGKAGLPADELTATVQRFNAFARSGVDEDYHRGESAYDRYYGDPSN
Rv3537|M.tuberculosis_H37Rv LAELAGKAGLPADELTATVQRFNAFARSGVDEDYHRGESAYDRYYGDPSN
MMAR_5024|M.marinum_M LEELAAKAGLPVDELTSTVSRFNGFARSGVDEDYHRGESAYDRYYGDPTN
MUL_4098|M.ulcerans_Agy99 LEELAAKAGLPVDELTSTVSRFNGFARSGVDEDYHRGESAYDRYYGDPTN
MSMEG_2869|M.smegmatis_MC2_155 LGGLARSIGVDVSVLTATLSRFNALARTGVDSDFGRGDSAYDRYYGDPTV
Mvan_2868|M.vanbaalenii_PYR-1 LPGLARQIGLETATFVATMDRFNDLADAGVDSDFHRGASAYDRYYGDPTH
TH_2946|M.thermoresistible__bu IPGLARAIGVDASTLDATVERFNRLARAGVDTDFGRGDSAYDRYYGDPTV
Mflv_4567|M.gilvum_PYR-GCK FSELAGLMGVPPETFGDTMRRFNESAGAGIDSDFHRGESAYDRYYGDPTV
MAV_3039|M.avium_104 LAELGAGIGVPVPEFVETMTRFNQNAAAGEDPDFGRGRSAYDRYYGDPTV
MAB_0081|M.abscessus_ATCC_1997 LADLAAMIGIPRDAFLATVCRFNESAAAGDDGDFHRGRSSYDRYYGDPTV
MLBr_01226|M.leprae_Br4923 AAAGRAYVSKLEPVTHHALKRRELQRVMSRDAAVMRNAAGLQRLSDTLAE
. :: * : . * *. :. :* . :
Mb3567|M.bovis_AF2122/97 KPNPNLGEVGHPPYYGAKMVPGDLGTKGGIRTDVNGRALRDDGSIIDGLY
Rv3537|M.tuberculosis_H37Rv KPNPNLGEVGHPPYYGAKMVPGDLGTKGGIRTDVNGRALRDDGSIIDGLY
MMAR_5024|M.marinum_M KPNPNLGEINHAPYYAAKMVPGDLGTKGGIRTDVNGRALRDDGSIIDGLY
MUL_4098|M.ulcerans_Agy99 KPNPNLGEINHAPYYAAKMVPGDLGTKGGIRTDVNGRALRDDGSIIDGLY
MSMEG_2869|M.smegmatis_MC2_155 TPNPNLRPLDDGPLYAVKVVLSDLGTCGGVRADARGRALREDGSVIEGLY
Mvan_2868|M.vanbaalenii_PYR-1 APNPNLRPVDSGPFYAVKVVLSDLGTCGGLRADARGRVLREDGSAVDGLY
TH_2946|M.thermoresistible__bu APNPNLRPLDHGPFYAVRVVLSDLGTCGGVRADHHARVLREDGSVIGGLY
Mflv_4567|M.gilvum_PYR-GCK TPSPNLRPLAKGPFYAVKMVLSDLGTCGGLRADERARVLREDGAAIEGLY
MAV_3039|M.avium_104 KPNPNLRPLVNGPFYAVRMVLSDLGTCGGLKTDERARVLREDGGPIAGLY
MAB_0081|M.abscessus_ATCC_1997 TPNPNLRPLRRGPFYAVRMVLSDLGTCGGLRADERARVLREDGSVIKGLY
MLBr_01226|M.leprae_Br4923 APIRHVTGRRDFEDVALTLTARAVAAAALARNESRGCHHCTEYPDTAPEH
* :: . :. :.: . : : .. : :
Mb3567|M.bovis_AF2122/97 AAGNVSAPVMGHTYPGPGGTIGPAMTFGYLAALHIADQAGKR--------
Rv3537|M.tuberculosis_H37Rv AAGNVSAPVMGHTYPGPGGTIGPAMTFGYLAALHIADQAGKR--------
MMAR_5024|M.marinum_M AAGNVSAPVMGHTYPGPGGTIGPAMTFGYLAALHIAGDR-----------
MUL_4098|M.ulcerans_Agy99 AAGNVSAPVMGHTYPGPGGTIGPAMTFGYLAALHIAGDR-----------
MSMEG_2869|M.smegmatis_MC2_155 AIGNTAANTFGASYPGAGATIGQGLVFGYIAARHAAGRLD----------
Mvan_2868|M.vanbaalenii_PYR-1 AIGNTAANTFGKTYPGAGATIGQGLVFGYIVAQHAAGRLD----------
TH_2946|M.thermoresistible__bu AIGNTAANVFGACYPGAGATIGQGLVFGYIAARHAATRAG----------
Mflv_4567|M.gilvum_PYR-GCK AIGNCAANAFGATYPGAGATIAQGLVYGYVAALDAARG------------
MAV_3039|M.avium_104 AIGNTAANAFGTTYPGAGATIAQGLVYGYIAAQEAARPSAAQEAARPSAS
MAB_0081|M.abscessus_ATCC_1997 AIGNTAANAFGATYPGAGATIAQGLVYGYIAAHDAAAR------------
MLBr_01226|M.leprae_Br4923 ARSTVIRLADDQNLVRAEALATVG--------------------------
* .. . . . . .
Mb3567|M.bovis_AF2122/97 ---
Rv3537|M.tuberculosis_H37Rv ---
MMAR_5024|M.marinum_M ---
MUL_4098|M.ulcerans_Agy99 ---
MSMEG_2869|M.smegmatis_MC2_155 ---
Mvan_2868|M.vanbaalenii_PYR-1 ---
TH_2946|M.thermoresistible__bu ---
Mflv_4567|M.gilvum_PYR-GCK ---
MAV_3039|M.avium_104 QPD
MAB_0081|M.abscessus_ATCC_1997 ---
MLBr_01226|M.leprae_Br4923 ---