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M. tuberculosis H37Rv Rv2790c (ltp1)

annotation: lipid-transfer protein
coordinates: 3098964 - 3100169
length: 401

TTKDHSLATATMPNQGSSNKVYVIGVGMTKFEKPGRREGWDYPDMARESGTKALRDAGIDYREVEQGYVG
YVYGESTSGQRALYELGMTGIPIVNVNNNCSTGSTALYLGAQAIRGGLADCVLALGFEKMQPGALGGGAD
DRESPLGRHVKALAEIDEFGFPVAPWMFGAAGREHMKKYGTTAEHFAKIGYKNHKHSVNNPYAQFQDEYT
LDDILASKMISDPLTKLQCSPTSDGSAAVVLASEDYLANHNLAGRAVEIVGQAMTTDFASTFDGSARNII
GYDMTVQAAQRVYQQSGLGPKDFGVIELHDCFSANELLLYEALGLCGPGEAPELIDDNQTTYGGRWVVNP
SGGLISKGHPLGATGLAQCAELTWQLRGTAEARQVDNVTAALQHNIGLGGAAVVTAYQRAER*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2790cltp1-100% (401)lipid-transfer protein
M. tuberculosis H37RvRv1627c-6e-5434.94% (415) lipid-transfer protein
M. tuberculosis H37RvRv0914c-3e-3228.09% (413) acetyl-CoA acetyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2813cltp10.0100.00% (401) lipid-transfer protein
M. gilvum PYR-GCKMflv_2025-0.089.85% (394) lipid-transfer protein
M. leprae Br4923MLBr_01158fadA45e-0822.52% (413) acetyl-CoA acetyltransferase
M. abscessus ATCC 19977MAB_2951c-0.078.75% (400) lipid-transfer protein
M. marinum MMMAR_1918ltp10.084.54% (401) lipid-transfer protein Ltp1
M. avium 104MAV_3681-0.086.84% (395) lipid-transfer protein
M. smegmatis MC2 155MSMEG_3844-1e-5133.25% (415) lipid-transfer protein
M. thermoresistible (build 8)TH_2429-2e-5533.73% (418) PUTATIVE lipid-transfer protein
M. ulcerans Agy99MUL_2143ltp10.084.29% (401) lipid-transfer protein
M. vanbaalenii PYR-1Mvan_4694-0.085.15% (404) lipid-transfer protein

CLUSTAL 2.0.9 multiple sequence alignment


Rv2790c|M.tuberculosis_H37Rv        MPNQGSSNKVYVIGVGMTKFEKPGR-----------REGWDYPDMARESG
Mb2813c|M.bovis_AF2122/97           MPNQGSSNKVYVIGVGMTKFEKPGR-----------REGWDYPDMARESG
Mflv_2025|M.gilvum_PYR-GCK          ------MNRVFVVGVGMTKFEKPGR-----------MENWDYPDMARESG
Mvan_4694|M.vanbaalenii_PYR-1       ------MKRVFVVGVGMTKFEKPGGRAARGADHEPGREGWDYPDMARESG
MAV_3681|M.avium_104                -----MSNKVYVVGVGMTKFEKPGR-----------REGWDYPGMARESG
MMAR_1918|M.marinum_M               -MPNNGSNRVFVIGVGMTKFEKPGRRE-----------GWDYPDMARESG
MUL_2143|M.ulcerans_Agy99           -MPNNGSNRVFVIGVGMTKFEKPGRRE-----------GWDYPDMARESG
MAB_2951c|M.abscessus_ATCC_199      -MAN----RVYVVGVGMTKFEKPGRRLN------DDGSAWDYPDMARESG
MSMEG_3844|M.smegmatis_MC2_155      ---MSAPEPVYILGAGMHPWGKWGR---------------DFTEYGVVAA
TH_2429|M.thermoresistible__bu      ----MSPEPVYILGAGMHPWGKWGR---------------DFTEYGVAAA
MLBr_01158|M.leprae_Br4923          -----MTTSVIVTGARTPIGKLMGS-----------LKDFSASDLGAITI
                                             * : *.        *                . .  .  : 

Rv2790c|M.tuberculosis_H37Rv        TKALRDAGIDYREVEQGY----VGYVYGESTSGQRALYELGMTGIPIVNV
Mb2813c|M.bovis_AF2122/97           TKALRDAGIDYREVEQGY----VGYVYGESTSGQRALYELGMTGIPIVNV
Mflv_2025|M.gilvum_PYR-GCK          TKALEDAGIAYSEIQQGY----VGYCSGDSTSGQRALYELGMTGIPIVNV
Mvan_4694|M.vanbaalenii_PYR-1       TKALEDAGVAYTEIQQGY----VGYCTGDSTSGQRALYELGMTGIPIANV
MAV_3681|M.avium_104                TNALADAGIDYREVQQGY----VGYVAGDSTSGQRALYELGMTGIPIVNV
MMAR_1918|M.marinum_M               TNALNDAGIEYREVEHAY----VGYVYGESTSGQRAVYELGMTGIPVVNV
MUL_2143|M.ulcerans_Agy99           TNALNDAGIEYREVEHAY----VGYVYGESTSGQRAVYELGMTGIPVVNV
MAB_2951c|M.abscessus_ATCC_199      TKALADAGIGYDLVEQAY----VGYVYGESTSGQRAVYELGMSGIPVVNV
MSMEG_3844|M.smegmatis_MC2_155      RAALAEAGLDWRQIQLVAGADTIRNGYPGFVAGATFAQKLGWNGVPVTSS
TH_2429|M.thermoresistible__bu      RAALAEAGLDWRQIQFVAGADTIRNGYPGFVAGSTFAQKLGWNGVPVSSS
MLBr_01158|M.leprae_Br4923          AAALKKANVAPSIVQYVIIGQVLTAGAGQMPARQAAVAAGIGWDVPALTI
                                      ** .*.:    ::       :        :           .:*  . 

Rv2790c|M.tuberculosis_H37Rv        NNNCSTGSTALYLGAQAIRGGLADCVLALGFEKMQPGALGGGADDRESPL
Mb2813c|M.bovis_AF2122/97           NNNCSTGSTALYLGAQAIRGGLADCVLALGFEKMQPGALGGGADDRESPL
Mflv_2025|M.gilvum_PYR-GCK          NNNCSTGSTALYLAAQSIRGGLADCVLALGFEKMQPGSLGGGAQDRESPL
Mvan_4694|M.vanbaalenii_PYR-1       NNNCSTGSTALYLAAQAIRGGLADCTLALGFEKMQPGSLGAGAEDRESPL
MAV_3681|M.avium_104                NNNCSTGSTALFLAAQAIRGGLVDCAIALGFEKMQPGSLGGGAQDRESPM
MMAR_1918|M.marinum_M               NNNCSTGSTALFLAAQAIRGGLADCTVALGFEKMKPGSLSSSYDDRTQPM
MUL_2143|M.ulcerans_Agy99           NNNCSTGSTALFLAAQAIRGGLADCTVALGFEKMKPGSLSSSYDDRTQPM
MAB_2951c|M.abscessus_ATCC_199      NNNCSTGSTALYLAAQSIRGGLADCALALGFEKMNPGSLGAMYDDRAQPM
MSMEG_3844|M.smegmatis_MC2_155      YAACASGSQALQSARAQILAGFCDVALVVGADTTPKGFFAPVGGERKNDP
TH_2429|M.thermoresistible__bu      YAACASGSQALQSARAQILAGFCDVALVIGADTTPKGFFAPVGGERKNDP
MLBr_01158|M.leprae_Br4923          NKMCLSGLDAIALADQLIRAGEFDVVVAGGQESMTKAPHLLMD----SRS
                                       * :*  *:  .   * .*  * .:. * :.   .          .  

Rv2790c|M.tuberculosis_H37Rv        GRHVKALAEIDEFGFPVAPWMFGAAGREHMKKYGTTAEHFAKIG-YKNHK
Mb2813c|M.bovis_AF2122/97           GRHVKALAEIDEFGFPVAPWMFGAAGREHMKKYGTTAEHFAKIG-YKNHK
Mflv_2025|M.gilvum_PYR-GCK          GRHVKALSEIDEFAFPVAPWMFGAAGREHMKKYGTTAEHFAKIG-FKNHK
Mvan_4694|M.vanbaalenii_PYR-1       KRHILALNEIDAMQFPVAPWMFGAAGREHMKKYGTTAEHFAKIG-YKNHK
MAV_3681|M.avium_104                GRHVKAMAEIDEFAMPVAPWMFGAAGREHMRQYGSTAEHFAKIG-YKNHK
MMAR_1918|M.marinum_M               DKHVKALAQIAEFAFPVAPWMFGAAGREHMQQYGSTAEHFAKIG-FKNHK
MUL_2143|M.ulcerans_Agy99           DKHVKALAQIAEFAFPVAPWMFGAAGREHMQQYGSTAEHFAKIG-FKNHK
MAB_2951c|M.abscessus_ATCC_199      EKHILALAEISEVLFPPASWMFGAAGREHMQQYGSTAEHFAKIG-HKNHK
MSMEG_3844|M.smegmatis_MC2_155      DWQRFHLIGATNTVY------FALLARRRMDLYGATLEDFAQVK-VKNAR
TH_2429|M.thermoresistible__bu      DWQRFHLIGATNTVY------FALLARRRMDLYGATAEDFAAVK-VKNAR
MLBr_01158|M.leprae_Br4923          GYKYGDVTIVDHLAYDGLHDVFTNQPMGALTEQRNDVEKFTRQEQDEFAA
                                      :   :              *       :       *.*:     :   

Rv2790c|M.tuberculosis_H37Rv        HSVNNPYAQFQDEYTLDDILASKMISDPLTKLQCSPTS---DGSAAVVLA
Mb2813c|M.bovis_AF2122/97           HSVNNPYAQFQDEYTLDDILASKMISDPLTKLQCSPTS---DGSAAVVLA
Mflv_2025|M.gilvum_PYR-GCK          HSVNNPYAQFQDEYSLDDILAAKMISDPLTKLQCSPTS---DGSAAVVLA
Mvan_4694|M.vanbaalenii_PYR-1       HSVNNPYAQFQDEYSLEDILAAKMISDPLTKLQCSPTS---DGSAAVVLA
MAV_3681|M.avium_104                HSVNNPFAQFQESYTLEDILAARMISDPLTKLQCSPTS---DGSGAAILA
MMAR_1918|M.marinum_M               HSVNNPFAQFQEAYTLDDILASRMIYEPLTKLQCSPTS---DGSGAAILA
MUL_2143|M.ulcerans_Agy99           HSVNNPFAQFQEAYTLDDILASRMIYEPLTKLRCSPTS---DGSGAAILA
MAB_2951c|M.abscessus_ATCC_199      HSVNNPYAQFQDEYTLDDILNSRMIYDPLTKLQCSPTS---DGSGAAILA
MSMEG_3844|M.smegmatis_MC2_155      HGLNNPNARYRKEASVEDVLASPVVSDPLRLLDICATS---DGAAALVVA
TH_2429|M.thermoresistible__bu      HGLHNPYARYRKETSIEDVLASPVVSDPLRLLDICATS---DGAAALIVA
MLBr_01158|M.leprae_Br4923          RSHQKAAAAWKDGVFADEVVPVSIPQSKGDSLQFTEDEGIRANTSAESLA
                                    :. ::. * ::.    ::::   :  .    *     .    .:.*  :*

Rv2790c|M.tuberculosis_H37Rv        SEDYLANHNLAGRAVEIVG--QAMTTDFASTFDGSARNIIGYDMTVQAAQ
Mb2813c|M.bovis_AF2122/97           SEDYLANHNLAGRAVEIVG--QAMTTDFASTFDGSARNIIGYDMTVQAAQ
Mflv_2025|M.gilvum_PYR-GCK          SEDYVARHDLAGQAVEIVG--QAMTTDFASTFDGSAANIIGHDMNVKAAQ
Mvan_4694|M.vanbaalenii_PYR-1       SEDYVARHDLAGRAVEIVG--QAMTTDFASTFDGSAANIIGHDMNVKAAQ
MAV_3681|M.avium_104                SEAFVDKHGLAGQAVEIVG--QAMTTDFASTFDGSAKNLIGYDMNVQAAQ
MMAR_1918|M.marinum_M               SESFVDSHGLAGRAVEIVG--QAMTTDFASTFDGSAKNLIGYDMNVQAAQ
MUL_2143|M.ulcerans_Agy99           SESFVDSHGLAGRAVEIVG--QAMTTDFASTFDGSAKNLIGYDMNVQAAR
MAB_2951c|M.abscessus_ATCC_199      SEAFVDRHGLASQAVEIVG--QAMTTDFQNSFDGTCKAIIGYHMNVSAAR
MSMEG_3844|M.smegmatis_MC2_155      SKSFVEKHLGSVEGVPSVRAISLQSPQYPQHLPELPDIATDSTAVVKAPE
TH_2429|M.thermoresistible__bu      SRSFAEKHLGSVQGVPSVRAVSTVTPRYPQHLPELPDIATDSTAVVDAPE
MLBr_01158|M.leprae_Br4923          GLKPAFRCGGTITPGSASQISDGAATVVVMNKEKAQQLGLTWLVEIGAHG
                                    .         :          .  :.                   : *  

Rv2790c|M.tuberculosis_H37Rv        RVYQ---------QSGLGPKDFGVIELHDCFSANELLLYEALGLCGPGEA
Mb2813c|M.bovis_AF2122/97           RVYQ---------QSGLGPKDFGVIELHDCFSANELLLYEALGLCGPGEA
Mflv_2025|M.gilvum_PYR-GCK          QVYS---------QSGLGPEDFQVIELHDCFSANELLLYEALGLCGPGEA
Mvan_4694|M.vanbaalenii_PYR-1       QVYD---------QSGLGPQDFQVIELHDCFSANELLLYEALGLCGPGEA
MAV_3681|M.avium_104                QVYD---------QSGLGPQDFQVIELHDCFSANELLLYEALGLCGPGEA
MMAR_1918|M.marinum_M               RVYQ---------QSGLGPEDFQVIELHDCFSANELLLYEALGLCGQGEA
MUL_2143|M.ulcerans_Agy99           RVYQ---------QSGLGPEDFQVIELHDCFSANELLLYEALGLCGQGEA
MAB_2951c|M.abscessus_ATCC_199      QVYD---------QSGLGAEDFQVIELHDCFSANEFLLYEALGLCGEGEA
MSMEG_3844|M.smegmatis_MC2_155      RVFKDQILDAAYAEAGIGPEDLSLAEVYDLSTALELDWYEHLGLCEKGEA
TH_2429|M.thermoresistible__bu      RVFKDQILDAAYAEAGIGPEDLSLAEVYDLSTALELDWYEHLGLCAKGEA
MLBr_01158|M.leprae_Br4923          VVAG--------PDSTLQSQPANAIKKAVDREGISVEQLDVVEINEAFAA
                                     *           :: : .:     :      . ..   : : :     *

Rv2790c|M.tuberculosis_H37Rv        PELIDDNQTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTWQLRGTAE
Mb2813c|M.bovis_AF2122/97           PELIDDNQTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTWQLRGTAE
Mflv_2025|M.gilvum_PYR-GCK          PRLIDDNDTTYGGRWVVNPSGGLISKGHPLGATGLAQCSELTWQLRGTAD
Mvan_4694|M.vanbaalenii_PYR-1       PALIDADDTTYGGRWVVNPSGGLISKGHPLGATGLAQCSELTWQLRGTAD
MAV_3681|M.avium_104                PKLIDNGDTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTWQLRGTAD
MMAR_1918|M.marinum_M               PKLIDNGDTTYGGRWVVNPSGGLISKGHPLGATGLAQCCELTWQLRGTAD
MUL_2143|M.ulcerans_Agy99           PKLIDNGDTTYGGRWVVNPSGGLISKGHPLGATGLAQCCELTWQLRGTAD
MAB_2951c|M.abscessus_ATCC_199      GKLIDNGDTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTWQLRGAAD
MSMEG_3844|M.smegmatis_MC2_155      EQLLRSGATTIGGRIPVNASGGLACFGEAIPAQAIAQVCELTWQLKGQAT
TH_2429|M.thermoresistible__bu      EQLLRSGATALGGRIPVNPSGGLACFGEAIPAQAIAQVCELTWQLRGQAT
MLBr_01158|M.leprae_Br4923          VALASARELGIAP-ELVNVNGGAIAVGHPLGMSGARITLHVALELARRGS
                                      *        .    ** .**  . *..:   .     .:: :*   . 

Rv2790c|M.tuberculosis_H37Rv        ARQVDNVTAALQHNIGLGGAAVVTAYQRAER
Mb2813c|M.bovis_AF2122/97           ARQVDNVTAALQHNIGLGGAAVVTAYQRAER
Mflv_2025|M.gilvum_PYR-GCK          KRQVDGVTAALQHNIGLGGAAVVTAYQRAER
Mvan_4694|M.vanbaalenii_PYR-1       KRQVDDVSAALQHNIGLGGAAVVTAYQRAER
MAV_3681|M.avium_104                KRQVENVSAALQHNIGLGGAAVVTAYQRAER
MMAR_1918|M.marinum_M               RRQVDDVTAALQHNIGLGGAAVVTAYQRAER
MUL_2143|M.ulcerans_Agy99           RRQVDNVTAALQHNIGLGGAAVVTAYQRAER
MAB_2951c|M.abscessus_ATCC_199      KRQVDRVDAALQHNIGLGGAAVITAYQRAER
MSMEG_3844|M.smegmatis_MC2_155      GRQVEGAKVGITANQGLFGHGSSVIVAR---
TH_2429|M.thermoresistible__bu      GRQVENAKVGITANQGLFGHGSSVIVAR---
MLBr_01158|M.leprae_Br4923          G-------YGVAALCGAGGQGDALILRAV--
                                             .:    *  * .