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M. thermoresistible (build 8) TH_3848 (fadE2_1)

annotation: acyl-CoA dehydrogenase FadE2_1
coordinates: 2134642 - 2135850
length: 403

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3848fadE2_1-100% (403)acyl-CoA dehydrogenase FadE2_1
M. thermoresistible (build 8)TH_3078-e-12460.05% (383) PUTATIVE acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_2913-4e-7939.95% (403) PUTATIVE acyl-CoA dehydrogenase domain protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0159cfadE21e-12658.23% (395) acyl-CoA dehydrogenase FADE2
M. gilvum PYR-GCKMflv_0734-1e-12456.97% (402) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37RvRv0154cfadE21e-12658.23% (395) acyl-CoA dehydrogenase FADE2
M. leprae Br4923MLBr_00737fadE254e-2228.67% (286) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977MAB_0255-1e-11351.58% (411) putative acyl-CoA dehydrogenase
M. marinum MMMAR_0156fadE2_11e-13356.39% (399) acyl-CoA dehydrogenase FadE2_1
M. avium 104MAV_5144-1e-12758.75% (400) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155MSMEG_0102-1e-12658.75% (400) putative acyl-CoA dehydrogenase
M. ulcerans Agy99MUL_4790fadE12e-7639.65% (401) acyl-CoA dehydrogenase FadE1
M. vanbaalenii PYR-1Mvan_0116-1e-12557.71% (402) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0734|M.gilvum_PYR-GCK          -------------MDFAMSAKAQDYHDRLTDFMTEHVFPAE----ESYHS
Mvan_0116|M.vanbaalenii_PYR-1       MDLTVYTCHIVAVMDFSMSAKAQDYHDRLTDFMTESVFPAE----ESYHA
MSMEG_0102|M.smegmatis_MC2_155      ----------MAGMDFAMSAKAADYHKRLTDFMVEFVFPAE----AEYHA
Mb0159c|M.bovis_AF2122/97           -----------------MSAKAIDYRTRLSDFMTEHVFGAE----ADYDD
Rv0154c|M.tuberculosis_H37Rv        -----------------MSAKAIDYRTRLSDFMTEHVFGAE----ADYDD
MAV_5144|M.avium_104                -------------MDFAMSAKASDYHKRLTDFMTEHVFAAE----AEYDK
MMAR_0156|M.marinum_M               ------------MSLFDISDRAKQYQSDLLEFMDSQVYPAE----AIYDE
TH_3848|M.thermoresistible__bu      -------------MDFEYSPRTRELLTRVRDFMEEYVYPAE----PVYDA
MAB_0255|M.abscessus_ATCC_1997      -------------MDFAPSARAAELIAAVREFIDAEVMPVERAVLAHHDE
MUL_4790|M.ulcerans_Agy99           ------------MWDFETDPEYQAKLDWVQEFMVNELEPLD---------
MLBr_00737|M.leprae_Br4923          ---MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHA---------
                                                        .       :  :    :             

Mflv_0734|M.gilvum_PYR-GCK          YR---AEAGPKDHTVPPVVEELK--KQAKERGLWNLFLPS---VSGLSNL
Mvan_0116|M.vanbaalenii_PYR-1       YR---AEAGPDDHTVPPVVEELK--KLAKARGLWNLFLPS---ESGLSNL
MSMEG_0102|M.smegmatis_MC2_155      YR---EEKGPKDHTVPPVVEELK--VKAKDRGLWNLFLPA---ESGLTNL
Mb0159c|M.bovis_AF2122/97           YR---RAAGPADHTAPPIIEELK--TKAKDRGLWNLFLSA---ESGLTNL
Rv0154c|M.tuberculosis_H37Rv        YR---RAAGPADHTAPPIIEELK--TKAKDRGLWNLFLSA---ESGLTNL
MAV_5144|M.avium_104                YR---HEAGPHDHTVPPVVEQLK--VKAKQQGLWNLFLPA---ESGLTNL
MMAR_0156|M.marinum_M               QM---RAAG-DPHFHPPILEELK--AAARNRGLWNLFHPHPEWGPGLTNL
TH_3848|M.thermoresistible__bu      QV---AEND-NFHEQPQIMRDLQ--AKAREQGLWNLFMTHGDYGAGLTNL
MAB_0255|M.abscessus_ATCC_1997      LLGARAGTTAELWHVPPELDSLK--AKARAAGLWNLFLPDPELGGGLSNS
MUL_4790|M.ulcerans_Agy99           ----LVALDPYDKKNPEMMAVLRPLQQVKNQGLWAAHLRPEVGGQGFGQV
MLBr_00737|M.leprae_Br4923          -----ADVDQRARFPEEALAALN------ASGFNAIHVPEEYGGQGADSV
                                                      :  *.        *:   .        *  . 

Mflv_0734|M.gilvum_PYR-GCK          EYAPLAELTGWSMEIAPEATNCAAPDTGNMETLHLFATEEQRTQWLEPLL
Mvan_0116|M.vanbaalenii_PYR-1       EYAPLAELTGWSMEIAPEATNCAAPDTGNMETLHLFATEEQRKQWLEPLL
MSMEG_0102|M.smegmatis_MC2_155      EYAPLAEITGWSMEIAPEALNCQAPDTGNMETLHLFANEAQRKQWLEPLL
Mb0159c|M.bovis_AF2122/97           EYAPLAEMTGWSMEIAPEALNCAAPDTGNMEILHMFGTEQQRAQWLRPLL
Rv0154c|M.tuberculosis_H37Rv        EYAPLAEMTGWSMEIAPEALNCAAPDTGNMEILHMFGTEQQRAQWLRPLL
MAV_5144|M.avium_104                EYAPLAEITGWSLEIAPEALNCAAPDTGNMETLHLFATEEQRKQWLEPLL
MMAR_0156|M.marinum_M               EYAPLAEILGRS-HIASEACNCSAPDTGNMEVLTLFGTDEHQQRYLKPLL
TH_3848|M.thermoresistible__bu      EYAPIAEEMGRS-IIGNEVFNCSAPDTGNMEILALYGTEKQRKQWLEPLL
MAB_0255|M.abscessus_ATCC_1997      EYAPLAEQMGRS-LFAPTVFNCNAPDSGNMEVLHRYGSQEQKEVWLEPLL
MUL_4790|M.ulcerans_Agy99           KLALLNEILGRS-RWAPSVFGCQAPDSGNAEILALFGTEDQKARYLQPLL
MLBr_00737|M.leprae_Br4923          AACIVIEEVARVDASASLIP---AVNKLGTMGLILRGSEELKKQVLPSLA
                                      . : *  .     .       * :. .   *   ..:  :   * .* 

Mflv_0734|M.gilvum_PYR-GCK          AGEIRSAFAMTEPAVASSDARNIETTMLRDGDDYVINGRKWWITGAADPR
Mvan_0116|M.vanbaalenii_PYR-1       AGEIRSAFAMTEPAVASSDARNIETTMLRDGDDYVINGRKWWITGAADPR
MSMEG_0102|M.smegmatis_MC2_155      AGEIRSAFAMTEPAVASSDARNIETTMLRDGDHYVINGRKWWITGAADPR
Mb0159c|M.bovis_AF2122/97           DGKIRSAFSMTEPAVASSDARNIETTISRDGADYVINGRKWWTSGAADPR
Rv0154c|M.tuberculosis_H37Rv        DGKIRSAFSMTEPAVASSDARNIETTISRDGADYVINGRKWWTSGAADPR
MAV_5144|M.avium_104                AGEIRSAFSMTEPAVASSDARNIETSIVRDGADYVINGRKWWTSGAADPR
MMAR_0156|M.marinum_M               EGKIRSAFAMTEPAVASSDATNVEMSMVRDGDSYILNGRKWFASNGMHRN
TH_3848|M.thermoresistible__bu      NCEIRSAFAMTEPDVASSDARNITATIRRDGDEYVLNGRKWYTSGILDPD
MAB_0255|M.abscessus_ATCC_1997      EGDIRSAFCMTEPDVASSDATNMAATAVVEGDEVVINGRKWWSTGVGHPD
MUL_4790|M.ulcerans_Agy99           DGEITSCYSMTEPQGGS-DPGSFVTAATRDGDSWIINGEKWFSTNAKH--
MLBr_00737|M.leprae_Br4923          AEGAMASYALSE-REAGSDAASMRTRAKADGDDWILNGFKCWITNGGK--
                                         :.:.::*   .. *. ..      :*   ::** * : :.  .  

Mflv_0734|M.gilvum_PYR-GCK          CKILIVMGRTNPDGPSHRQQSMILVPTDTPGVSIERSLPVFGWQDQHG-H
Mvan_0116|M.vanbaalenii_PYR-1       CKILIVMGRTNPDGPSHRQQSMILVPADTPGVDIQRSLPVFGWQDQHG-H
MSMEG_0102|M.smegmatis_MC2_155      CKILIVMGRTNPDAAAHQQQSMILVPVDTPGVDIQRSLPVFGWQDQHG-H
Mb0159c|M.bovis_AF2122/97           CKILIVMGRTNPDAAAHQQQSMVLVPIDTPGVTIVRSTPVFGWQDRHG-H
Rv0154c|M.tuberculosis_H37Rv        CKILIVMGRTNPDAAAHQQQSMVLVPIDTPGVTIVRSTPVFGWQDRHG-H
MAV_5144|M.avium_104                CKILIVMGRTNPDAASHQQQSMVLVPMDTPGVTVVRSTPVFGWQDQHG-H
MMAR_0156|M.marinum_M               CKVLIVMGKTDPTAPVHRQQSMMVVPIDAPGLTVRRNLPVFGYQDREG-H
TH_3848|M.thermoresistible__bu      CKLIIFMGKSDPDAPTYKQQSMILVPADAPGIEVLRDLPMFGYKDRLG-H
MAB_0255|M.abscessus_ATCC_1997      CKVIIFMGLTDPNAHRYARHSMVLVPMDTPGITVERMLPTMGFYDEPGGH
MUL_4790|M.ulcerans_Agy99           ASFFIVMAVTNPQARTYEKMSLFIVPAETPGIEIVRNVGVGTESSKHASH
MLBr_00737|M.leprae_Br4923          STWYTVMAVTDPDKGANG-ISAFIVHKDDEGFSIGPKEKKLGIKGSPT--
                                    ..   .*. ::*        * .:*  :  *. :          .     

Mflv_0734|M.gilvum_PYR-GCK          CEITFDNVRVPASNLLDEEGSGFAIAQARLGPGRIHHCMRAIGAAERALA
Mvan_0116|M.vanbaalenii_PYR-1       CEIVFDNVRVPASNLLDEEGSGFAIAQARLGPGRIHHCMRAIGAAERALA
MSMEG_0102|M.smegmatis_MC2_155      CEIVFNDVRVPAENLLDVEGSGFAIAQARLGPGRIHHCMRAIGAAERALT
Mb0159c|M.bovis_AF2122/97           CEIDYHNVRVPATNLLGEEGSGFAIAQARLGPGRIHHCMRALGAAERALA
Rv0154c|M.tuberculosis_H37Rv        CEIDYHNVRVPATNLLGEEGSGFAIAQARLGPGRIHHCMRALGAAERALA
MAV_5144|M.avium_104                CEIVYDNVRVPVTNLLGEEGSGFAIAQARLGPGRIHHCMRALGGAERALA
MMAR_0156|M.marinum_M               AEIDFVDVRVPVKDVLKGEGEGFAISQARLGPGRIHHCMRAIGMAERALE
TH_3848|M.thermoresistible__bu      GEVQFTDVRVPAENMLGNEGDGFAIAQGRLGPGRMHYAMRAIGFAERALD
MAB_0255|M.abscessus_ATCC_1997      GVVSFDNVRLPADAFIAGPGKGFEIAQGRLGPGRVHHAMRLIGLAEVALE
MUL_4790|M.ulcerans_Agy99           GYVRYHDVRVPADHVLGGEGQAFMTAQTRLGGGRIHHAMRTIALARRAFD
MLBr_00737|M.leprae_Br4923          TELYFDKCRIPGDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALD
                                      : : . *:*   .:   * .*  :   *.  *     : :. *. *: 

Mflv_0734|M.gilvum_PYR-GCK          LMVDRVQTRIAFGKPLAEQGVVREAIAKSRNDIEQTRMLCHKAAWTIDQH
Mvan_0116|M.vanbaalenii_PYR-1       LMIDRVQTRIAFGKPLAEQGVVREAIAKSRNEIEQTRLLCHKAAWTIDQQ
MSMEG_0102|M.smegmatis_MC2_155      LMVDRVQKRVAFGKPLAEQGVVREAIAKSRNEIDQARLLCEKAAWTIDLQ
Mb0159c|M.bovis_AF2122/97           LMVNRVRNRVAFGRPLAEQGVVQQAIAQSRNEIDQARLLCEKAAWTIDQH
Rv0154c|M.tuberculosis_H37Rv        LMVNRVRNRVAFGRPLAEQGVVQQAIAQSRNEIDQARLLCEKAAWTIDQH
MAV_5144|M.avium_104                LMVDRAQKRVAFGRPLAEQGVVRESIAKSRNEIDQARLLCEKAAWTIDQH
MMAR_0156|M.marinum_M               LMCKRAQSRVTFGKPISENANVRDWIAEARIEIEMIRLLTLKAAYLMDTV
TH_3848|M.thermoresistible__bu      LMCRRALTREAFGGPLAQRGVVREWIARSRMEIDQIRLLTFKAAWLMDTR
MAB_0255|M.abscessus_ATCC_1997      HACRRGLDRTAFGKPLVNLGGNRERIADARIAINQTRLLVLHAAWLLDTV
MUL_4790|M.ulcerans_Agy99           MMCERAVSRQTRHGRLSDLQMTQEKVADSWIQIEQFRLLVLRTAWLIDKH
MLBr_00737|M.leprae_Br4923          AAIVYTKDRKQFGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAERG
                                            *      :      :  :*     ::  *::   :*   :  

Mflv_0734|M.gilvum_PYR-GCK          GNKSKDAQLLVAQIKAVAPQMACDVIDRAIQVHGGAGVSDDFPLARLYSW
Mvan_0116|M.vanbaalenii_PYR-1       GNKSKDAQLLVAQIKAVAPQMACDVIDRAIQVHGGAGVCDDFPLARLYSW
MSMEG_0102|M.smegmatis_MC2_155      GNK--AAHVLVSQIKSVAPQVACNVLDRAIQVHGAAGVGDDFPLARLYAW
Mb0159c|M.bovis_AF2122/97           GNK--EARHLVAMIKAVAPRVACDVIDRAIQVHGAAGVSDDTPLARLYGW
Rv0154c|M.tuberculosis_H37Rv        GNK--EARHLVAMIKAVAPRVACDVIDRAIQVHGAAGVSDDTPLARLYGW
MAV_5144|M.avium_104                GNK--AAHLLVSQIKAVAPKVACDVIDRAIQVHGAAGVSDDTVLARLYGW
MMAR_0156|M.marinum_M               GNK--QARTEIAAIKVAAPNIALKIVDRAIQVHGGGGVTDDFPLAMAWAH
TH_3848|M.thermoresistible__bu      GNA--AARSEVAAIKVAAMETAHQVVNRAVQTFGAAGVSDDTVLARLFAI
MAB_0255|M.abscessus_ATCC_1997      GIMG--ALSAVSEIKVAAPNMAQQVIDMAIQIHGGGGLSNDFPLAAAWVN
MUL_4790|M.ulcerans_Agy99           HDYQ-KVRRDIAAVKVAMPQVLHDVVQRAMHLHGALGVSDEMPFVKMMVA
MLBr_00737|M.leprae_Br4923          EPD---LGFISAASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFMRD
                                               :  *        .:   *:: .*. *  .:  .      

Mflv_0734|M.gilvum_PYR-GCK          HRAMRLFDGPDEVHMRTIARAELGREKSALATAACRVSHPGAAG------
Mvan_0116|M.vanbaalenii_PYR-1       HRAMRLFDGPDEVHMRTIARAELGREKSAMATAASRQSDTAASRQSNPAA
MSMEG_0102|M.smegmatis_MC2_155      HRAMRLFDGPDEVHMRTIARSELGREKSPLALAVTK--------------
Mb0159c|M.bovis_AF2122/97           HRAMRIFDGPDEVHLRSIARAELSREKSTFAAAVT---------------
Rv0154c|M.tuberculosis_H37Rv        HRAMRIFDGPDEVHLRSIARAELSREKSTFAAAVT---------------
MAV_5144|M.avium_104                HRAMRIFDGPDEVHMRTIARAELGREKSALAAAVTAHA------------
MMAR_0156|M.marinum_M               LRTLRLADGPDEVHKRAIATQELRKYRNGAHGS-----------------
TH_3848|M.thermoresistible__bu      TRALQIADGPNEVHLRTIARLELERYRDE---------------------
MAB_0255|M.abscessus_ATCC_1997      ARALRLADGPDEVHRGVVARIELAKYAND---------------------
MUL_4790|M.ulcerans_Agy99           AESLGIADGATELHKMTVARRTLRQYEPVATPFPSQHIPTRRAAAEARLA
MLBr_00737|M.leprae_Br4923          AKITQIYEGTNQIQRVVMSRALLR--------------------------
                                     .   : :*. :::   ::   *                           

Mflv_0734|M.gilvum_PYR-GCK          ----------
Mvan_0116|M.vanbaalenii_PYR-1       SRQSETAVTG
MSMEG_0102|M.smegmatis_MC2_155      ----------
Mb0159c|M.bovis_AF2122/97           ----------
Rv0154c|M.tuberculosis_H37Rv        ----------
MAV_5144|M.avium_104                ----------
MMAR_0156|M.marinum_M               ----------
TH_3848|M.thermoresistible__bu      ----------
MAB_0255|M.abscessus_ATCC_1997      ----------
MUL_4790|M.ulcerans_Agy99           ERLEHSIAEF
MLBr_00737|M.leprae_Br4923          ----------