For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_3078 (-)

annotation: acyl-CoA dehydrogenase domain protein
coordinates: 3480983 - 3482182
length: 400

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3078--100% (400)acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_3848-e-12460.05% (383) PUTATIVE acyl-CoA dehydrogenase FadE2_1
M. thermoresistible (build 8)TH_2913-3e-7742.75% (400) PUTATIVE acyl-CoA dehydrogenase domain protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0159cfadE20.079.08% (392) acyl-CoA dehydrogenase FADE2
M. gilvum PYR-GCKMflv_0734-0.085.39% (397) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37RvRv0154cfadE20.079.08% (392) acyl-CoA dehydrogenase FADE2
M. leprae Br4923MLBr_00737fadE253e-2327.59% (290) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977MAB_0255-1e-10153.20% (359) putative acyl-CoA dehydrogenase
M. marinum MMMAR_0374fadE20.080.36% (392) acyl-CoA dehydrogenase FadE2
M. avium 104MAV_5144-0.083.67% (392) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155MSMEG_0102-0.087.09% (395) putative acyl-CoA dehydrogenase
M. ulcerans Agy99MUL_4790fadE12e-6336.64% (393) acyl-CoA dehydrogenase FadE1
M. vanbaalenii PYR-1Mvan_0116-0.084.46% (399) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0159c|M.bovis_AF2122/97           -----------------MSAKAIDYRTRLSDFMTEHVFGAEADYDDYRRA
Rv0154c|M.tuberculosis_H37Rv        -----------------MSAKAIDYRTRLSDFMTEHVFGAEADYDDYRRA
MMAR_0374|M.marinum_M               -------MSYRGGMDFAMSAKAIDYHQRLSDFMTEYVFPAEADYDKYRED
MAV_5144|M.avium_104                -------------MDFAMSAKASDYHKRLTDFMTEHVFAAEAEYDKYRHE
TH_3078|M.thermoresistible__bu      ----------------------------LTEFMTEFVFPAEPEYDRYREE
MSMEG_0102|M.smegmatis_MC2_155      ----------MAGMDFAMSAKAADYHKRLTDFMVEFVFPAEAEYHAYREE
Mflv_0734|M.gilvum_PYR-GCK          -------------MDFAMSAKAQDYHDRLTDFMTEHVFPAEESYHSYRAE
Mvan_0116|M.vanbaalenii_PYR-1       MDLTVYTCHIVAVMDFSMSAKAQDYHDRLTDFMTESVFPAEESYHAYRAE
MAB_0255|M.abscessus_ATCC_1997      -------------MDFAPSARAAELIAAVREFIDAEVMPVERAVLAHHDE
MUL_4790|M.ulcerans_Agy99           ------------MWDFETDPEYQAKLDWVQEFMVNELEPLDLVALDPYDK
MLBr_00737|M.leprae_Br4923          ----------MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAAD
                                                                  ::        :         

Mb0159c|M.bovis_AF2122/97           A-GPAD------HTAPPIIEELKTKAKDRGLWNLFLSAE---SGLTNLEY
Rv0154c|M.tuberculosis_H37Rv        A-GPAD------HTAPPIIEELKTKAKDRGLWNLFLSAE---SGLTNLEY
MMAR_0374|M.marinum_M               A-GPND------HTVPPVVEELKANAKARGLWNLFLPAE---SGLTNLEY
MAV_5144|M.avium_104                A-GPHD------HTVPPVVEQLKVKAKQQGLWNLFLPAE---SGLTNLEY
TH_3078|M.thermoresistible__bu      K-GPND------FTVPPIVEELKVKARERGLWNLFLPPV---SGLTNLEY
MSMEG_0102|M.smegmatis_MC2_155      K-GPKD------HTVPPVVEELKVKAKDRGLWNLFLPAE---SGLTNLEY
Mflv_0734|M.gilvum_PYR-GCK          A-GPKD------HTVPPVVEELKKQAKERGLWNLFLPSV---SGLSNLEY
Mvan_0116|M.vanbaalenii_PYR-1       A-GPDD------HTVPPVVEELKKLAKARGLWNLFLPSE---SGLSNLEY
MAB_0255|M.abscessus_ATCC_1997      LLGARAGTTAELWHVPPELDSLKAKARAAGLWNLFLPDPELGGGLSNSEY
MUL_4790|M.ulcerans_Agy99           K-----------NPEMMAVLRPLQQVKNQGLWAAHLRPEVGGQGFGQVKL
MLBr_00737|M.leprae_Br4923          V-----------DQRARFPEEALAALNASGFNAIHVPEEYGGQGADSVAA
                                                              .  *:   .:       *  .   

Mb0159c|M.bovis_AF2122/97           APLAEMTGWSMEIAPEALNCAAPDTGNMEILHMFGTEQQRAQWLRPLLDG
Rv0154c|M.tuberculosis_H37Rv        APLAEMTGWSMEIAPEALNCAAPDTGNMEILHMFGTEQQRAQWLRPLLDG
MMAR_0374|M.marinum_M               APLAELTGWSLEIAPEALNCAAPDTGNMEILHMFGTDEQRRQWLDPLLHG
MAV_5144|M.avium_104                APLAEITGWSLEIAPEALNCAAPDTGNMETLHLFATEEQRKQWLEPLLAG
TH_3078|M.thermoresistible__bu      AALAEISGWSTVIAPEAINCAAPDTGNMETLHLFANEQQRKQWLEPLLNG
MSMEG_0102|M.smegmatis_MC2_155      APLAEITGWSMEIAPEALNCQAPDTGNMETLHLFANEAQRKQWLEPLLAG
Mflv_0734|M.gilvum_PYR-GCK          APLAELTGWSMEIAPEATNCAAPDTGNMETLHLFATEEQRTQWLEPLLAG
Mvan_0116|M.vanbaalenii_PYR-1       APLAELTGWSMEIAPEATNCAAPDTGNMETLHLFATEEQRKQWLEPLLAG
MAB_0255|M.abscessus_ATCC_1997      APLAEQMGRSL-FAPTVFNCNAPDSGNMEVLHRYGSQEQKEVWLEPLLEG
MUL_4790|M.ulcerans_Agy99           ALLNEILGRSR-WAPSVFGCQAPDSGNAEILALFGTEDQKARYLQPLLDG
MLBr_00737|M.leprae_Br4923          CIVIEEVARVDASASLIP---AVNKLGTMGLILRGSEELKKQVLPSLAAE
                                    . : *  .     *.      * :. .   *   ..:  :   * .*   

Mb0159c|M.bovis_AF2122/97           KIRSAFSMTEPAVASSDARNIETTISRDGADYVINGRKWWTSGAADPRCK
Rv0154c|M.tuberculosis_H37Rv        KIRSAFSMTEPAVASSDARNIETTISRDGADYVINGRKWWTSGAADPRCK
MMAR_0374|M.marinum_M               EIRSAFSMTEPAVASSDARNIETTISRDGADYIINGRKWWTSGAADPRCK
MAV_5144|M.avium_104                EIRSAFSMTEPAVASSDARNIETSIVRDGADYVINGRKWWTSGAADPRCK
TH_3078|M.thermoresistible__bu      EIRSAFAMTEPAVASSDARNIETTMLRDGDHYVINGRKWWITGAADPRCK
MSMEG_0102|M.smegmatis_MC2_155      EIRSAFAMTEPAVASSDARNIETTMLRDGDHYVINGRKWWITGAADPRCK
Mflv_0734|M.gilvum_PYR-GCK          EIRSAFAMTEPAVASSDARNIETTMLRDGDDYVINGRKWWITGAADPRCK
Mvan_0116|M.vanbaalenii_PYR-1       EIRSAFAMTEPAVASSDARNIETTMLRDGDDYVINGRKWWITGAADPRCK
MAB_0255|M.abscessus_ATCC_1997      DIRSAFCMTEPDVASSDATNMAATAVVEGDEVVINGRKWWSTGVGHPDCK
MUL_4790|M.ulcerans_Agy99           EITSCYSMTEPQGGS-DPGSFVTAATRDGDSWIINGEKWFSTNAKH--AS
MLBr_00737|M.leprae_Br4923          GAMASYALSE-REAGSDAASMRTRAKADGDDWILNGFKCWITNGGK--ST
                                       :.:.::*   .. *. .: :    :*   ::** * : :.  .  ..

Mb0159c|M.bovis_AF2122/97           ILIVMGRTNPDAAAHQQQSMVLVPIDTPGVTIVRSTPVFGWQDRHG-HCE
Rv0154c|M.tuberculosis_H37Rv        ILIVMGRTNPDAAAHQQQSMVLVPIDTPGVTIVRSTPVFGWQDRHG-HCE
MMAR_0374|M.marinum_M               ILIVMGRTNPDAAAHQQQSMILVPTDTPGVTIARSTPVFGWQDQHG-HCE
MAV_5144|M.avium_104                ILIVMGRTNPDAASHQQQSMVLVPMDTPGVTVVRSTPVFGWQDQHG-HCE
TH_3078|M.thermoresistible__bu      ILIVMGRTNPDAASHQQQSMILVPADTPGVDIRRSLPVFGWQDQHG-HCE
MSMEG_0102|M.smegmatis_MC2_155      ILIVMGRTNPDAAAHQQQSMILVPVDTPGVDIQRSLPVFGWQDQHG-HCE
Mflv_0734|M.gilvum_PYR-GCK          ILIVMGRTNPDGPSHRQQSMILVPTDTPGVSIERSLPVFGWQDQHG-HCE
Mvan_0116|M.vanbaalenii_PYR-1       ILIVMGRTNPDGPSHRQQSMILVPADTPGVDIQRSLPVFGWQDQHG-HCE
MAB_0255|M.abscessus_ATCC_1997      VIIFMGLTDPNAHRYARHSMVLVPMDTPGITVERMLPTMGFYDEPGGHGV
MUL_4790|M.ulcerans_Agy99           FFIVMAVTNPQARTYEKMSLFIVPAETPGIEIVRNVGVGTESSKHASHGY
MLBr_00737|M.leprae_Br4923          WYTVMAVTDPDKGANG-ISAFIVHKDDEGFSIGPKEKKLGIKGSPT--TE
                                       .*. *:*:       * .:*  :  *. :          .       

Mb0159c|M.bovis_AF2122/97           IDYHNVRVPATNLLGEEGSGFAIAQARLGPGRIHHCMRALGAAERALALM
Rv0154c|M.tuberculosis_H37Rv        IDYHNVRVPATNLLGEEGSGFAIAQARLGPGRIHHCMRALGAAERALALM
MMAR_0374|M.marinum_M               VVYDNVRVPATNLLGEEGTGFAIAQARLGPGRIHHCMRALGGAERALALM
MAV_5144|M.avium_104                IVYDNVRVPVTNLLGEEGSGFAIAQARLGPGRIHHCMRALGGAERALALM
TH_3078|M.thermoresistible__bu      IVFDNVRVPVENLLGEEGAGFAIAQARLGPGRIHHCMRALGAAERALALM
MSMEG_0102|M.smegmatis_MC2_155      IVFNDVRVPAENLLDVEGSGFAIAQARLGPGRIHHCMRAIGAAERALTLM
Mflv_0734|M.gilvum_PYR-GCK          ITFDNVRVPASNLLDEEGSGFAIAQARLGPGRIHHCMRAIGAAERALALM
Mvan_0116|M.vanbaalenii_PYR-1       IVFDNVRVPASNLLDEEGSGFAIAQARLGPGRIHHCMRAIGAAERALALM
MAB_0255|M.abscessus_ATCC_1997      VSFDNVRLPADAFIAGPGKGFEIAQGRLGPGRVHHAMRLIGLAEVALEHA
MUL_4790|M.ulcerans_Agy99           VRYHDVRVPADHVLGGEGQAFMTAQTRLGGGRIHHAMRTIALARRAFDMM
MLBr_00737|M.leprae_Br4923          LYFDKCRIPGDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAA
                                    : :.. *:*   .:   * .*  *   *.  *     : :. *. *:   

Mb0159c|M.bovis_AF2122/97           VNRVRNRVAFGRPLAEQGVVQQAIAQSRNEIDQARLLCEKAAWTIDQHGN
Rv0154c|M.tuberculosis_H37Rv        VNRVRNRVAFGRPLAEQGVVQQAIAQSRNEIDQARLLCEKAAWTIDQHGN
MMAR_0374|M.marinum_M               VDRARNRVAFGRPLAEQGVVQQAIAKSRNEIDQARLLCEKAAWTIDRHGN
MAV_5144|M.avium_104                VDRAQKRVAFGRPLAEQGVVRESIAKSRNEIDQARLLCEKAAWTIDQHGN
TH_3078|M.thermoresistible__bu      VDRVQKRVAFGKPLAEQGVVREAIAKSRNEIDQARMLCHKAAWTIDQLGN
MSMEG_0102|M.smegmatis_MC2_155      VDRVQKRVAFGKPLAEQGVVREAIAKSRNEIDQARLLCEKAAWTIDLQGN
Mflv_0734|M.gilvum_PYR-GCK          VDRVQTRIAFGKPLAEQGVVREAIAKSRNDIEQTRMLCHKAAWTIDQHGN
Mvan_0116|M.vanbaalenii_PYR-1       IDRVQTRIAFGKPLAEQGVVREAIAKSRNEIEQTRLLCHKAAWTIDQQGN
MAB_0255|M.abscessus_ATCC_1997      CRRGLDRTAFGKPLVNLGGNRERIADARIAINQTRLLVLHAAWLLDTVGI
MUL_4790|M.ulcerans_Agy99           CERAVSRQTRHGRLSDLQMTQEKVADSWIQIEQFRLLVLRTAWLIDKHHD
MLBr_00737|M.leprae_Br4923          IVYTKDRKQFGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGEP
                                          *      :      :  :*.    ::  *::   :*   :    

Mb0159c|M.bovis_AF2122/97           --KEARHLVAMIKAVAPRVACDVIDRAIQVHGAAGVSDDTPLARLYGWHR
Rv0154c|M.tuberculosis_H37Rv        --KEARHLVAMIKAVAPRVACDVIDRAIQVHGAAGVSDDTPLARLYGWHR
MMAR_0374|M.marinum_M               --KEARHLVAMIKAVAPQVACDVIDRAIQVHGAAGVSNDTPLARLYSWHR
MAV_5144|M.avium_104                --KAAHLLVSQIKAVAPKVACDVIDRAIQVHGAAGVSDDTVLARLYGWHR
TH_3078|M.thermoresistible__bu      KHKEAQVQVAQIKAVAPTVACNVIDRAIQVHGGAGVSDDFPLARLYAWHR
MSMEG_0102|M.smegmatis_MC2_155      --KAAHVLVSQIKSVAPQVACNVLDRAIQVHGAAGVGDDFPLARLYAWHR
Mflv_0734|M.gilvum_PYR-GCK          KSKDAQLLVAQIKAVAPQMACDVIDRAIQVHGGAGVSDDFPLARLYSWHR
Mvan_0116|M.vanbaalenii_PYR-1       KSKDAQLLVAQIKAVAPQMACDVIDRAIQVHGGAGVCDDFPLARLYSWHR
MAB_0255|M.abscessus_ATCC_1997      --MGALSAVSEIKVAAPNMAQQVIDMAIQIHGGGGLSNDFPLAAAWVNAR
MUL_4790|M.ulcerans_Agy99           -YQKVRRDIAAVKVAMPQVLHDVVQRAMHLHGALGVSDEMPFVKMMVAAE
MLBr_00737|M.leprae_Br4923          ---DLGFISAASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFMRDAK
                                             :  *   . :  :*   *:::.*. *  .:  .       .

Mb0159c|M.bovis_AF2122/97           AMRIFDGPDEVHLRSIARAELSREKSTFAAAVT-----------------
Rv0154c|M.tuberculosis_H37Rv        AMRIFDGPDEVHLRSIARAELSREKSTFAAAVT-----------------
MMAR_0374|M.marinum_M               AMRIFDGPDEVHMRSIARAELGREKSAFAAAVTSHG--------------
MAV_5144|M.avium_104                AMRIFDGPDEVHMRTIARAELGREKSALAAAVTAHA--------------
TH_3078|M.thermoresistible__bu      AMRLFDGPDEVHMRTIARAELGKEKSPLAAAAIKVSSS------------
MSMEG_0102|M.smegmatis_MC2_155      AMRLFDGPDEVHMRTIARSELGREKSPLALAVTK----------------
Mflv_0734|M.gilvum_PYR-GCK          AMRLFDGPDEVHMRTIARAELGREKSALATAACRVSHPGAAG--------
Mvan_0116|M.vanbaalenii_PYR-1       AMRLFDGPDEVHMRTIARAELGREKSAMATAASRQSDTAASRQSNPAASR
MAB_0255|M.abscessus_ATCC_1997      ALRLADGPDEVHRGVVARIELAKYAND-----------------------
MUL_4790|M.ulcerans_Agy99           SLGIADGATELHKMTVARRTLRQYEPVATPFPSQHIPTRRAAAEARLAER
MLBr_00737|M.leprae_Br4923          ITQIYEGTNQIQRVVMSRALLR----------------------------
                                       : :*. :::   ::*  *                             

Mb0159c|M.bovis_AF2122/97           --------
Rv0154c|M.tuberculosis_H37Rv        --------
MMAR_0374|M.marinum_M               --------
MAV_5144|M.avium_104                --------
TH_3078|M.thermoresistible__bu      --------
MSMEG_0102|M.smegmatis_MC2_155      --------
Mflv_0734|M.gilvum_PYR-GCK          --------
Mvan_0116|M.vanbaalenii_PYR-1       QSETAVTG
MAB_0255|M.abscessus_ATCC_1997      --------
MUL_4790|M.ulcerans_Agy99           LEHSIAEF
MLBr_00737|M.leprae_Br4923          --------