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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3764 | - | - | 100% (347) | cytochrome P450 |
| M. thermoresistible (build 8) | TH_4183 | - | e-149 | 74.93% (339) | PUTATIVE cytochrome P450 |
| M. thermoresistible (build 8) | TH_2733 | - | e-137 | 69.62% (339) | PUTATIVE cytochrome P450 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3575c | cyp125 | 7e-49 | 34.22% (339) | cytochrome P450 125 |
| M. gilvum PYR-GCK | Mflv_5053 | - | 1e-151 | 77.22% (338) | cytochrome P450 |
| M. tuberculosis H37Rv | Rv3545c | cyp125 | 7e-49 | 34.22% (339) | cytochrome P450 125 |
| M. leprae Br4923 | MLBr_02088 | - | 5e-25 | 27.10% (310) | putative cytochrome p450 |
| M. abscessus ATCC 19977 | MAB_3825 | - | 1e-130 | 64.90% (339) | cytochrome P450 |
| M. marinum M | MMAR_3999 | cyp108B4 | 1e-135 | 71.18% (340) | cytochrome P450 108B4 Cyp108B4 |
| M. avium 104 | MAV_1609 | - | 1e-138 | 70.88% (340) | cytochrome P450 family protein |
| M. smegmatis MC2 155 | MSMEG_1429 | - | 1e-158 | 80.00% (340) | cytochrome P450-terp |
| M. ulcerans Agy99 | MUL_3863 | cyp108B4 | 1e-134 | 71.18% (340) | cytochrome P450 108B4 Cyp108B4 |
| M. vanbaalenii PYR-1 | Mvan_1301 | - | 1e-156 | 78.11% (338) | cytochrome P450 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3575c|M.bovis_AF2122/97 MSWNHQSVEIAVRRTTVPSPNLPPGFDFTDPAIYAER-LPVAEFAELRSA
Rv3545c|M.tuberculosis_H37Rv MSWNHQSVEIAVRRTTVPSPNLPPGFDFTDPAIYAER-LPVAEFAELRSA
Mflv_5053|M.gilvum_PYR-GCK -----------MSTPTMDRDSQEAAKVLADPKAYADDDRLHSALSYLRAN
Mvan_1301|M.vanbaalenii_PYR-1 -----------MSTPTMNQESQEAAKVLADPTAYADDQRLHKALAHLRAN
MSMEG_1429|M.smegmatis_MC2_155 -----------MSTPTMD----DAAKALADPTAYADDARLHEALARLRAE
TH_3764|M.thermoresistible__bu ----------------MD----EAARIFADPTAYADEARLHAALAHLRAH
MMAR_3999|M.marinum_M -----------MSAPTMD----EAA-LLADPLAYTDETRLHAALTRLRAQ
MUL_3863|M.ulcerans_Agy99 -----------MSAPTMD----EAA-LLADPLAYTDETRLHAALTRLRAQ
MAV_1609|M.avium_104 -----------MSTTTMD----EAAKLLADPMAYTDEQRLHAALTHLRAN
MAB_3825|M.abscessus_ATCC_1997 -----------MATALSEIE--EAGRVLADPAAYADELRLHAAMTLLRRE
MLBr_02088|M.leprae_Br4923 --------MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLI
* : **
Mb3575c|M.bovis_AF2122/97 APIWWNG-QDPGKGGGFH---DGGFWAITKLNDVKEISRHSDVFSSYENG
Rv3545c|M.tuberculosis_H37Rv APIWWNG-QDPGKGGGFH---DGGFWAITKLNDVKEISRHSDVFSSYENG
Mflv_5053|M.gilvum_PYR-GCK DPVVWVD-HPPYRP----------FWAITKHADIMAIERANDLFLSAPRP
Mvan_1301|M.vanbaalenii_PYR-1 DPVAWVD-HPPYRP----------FWAITKHADIMAIERANDLFLSEPRP
MSMEG_1429|M.smegmatis_MC2_155 NPVAWVD-QAPYRP----------FWAITKHADIMAIERANDLWLSAPRP
TH_3764|M.thermoresistible__bu NPVAWVD-QPPYRP----------FFAITRHTDVMDIERANDLWLSEPRP
MMAR_3999|M.marinum_M APVALVD-VPNYRR----------FWAITRHADVMDIERDNTLFTNWPRP
MUL_3863|M.ulcerans_Agy99 APVALVD-VPNYRR----------FWAITRHADVMDIERDNTLFTNWPRP
MAV_1609|M.avium_104 APVSWVE-VPNYKP----------FWAITKHADVMDIERENMLFTNWPRP
MAB_3825|M.abscessus_ATCC_1997 QPVTKVI-TDDYRP----------FWAVTKHDDIMAVERDNALWINEPRP
MLBr_02088|M.leprae_Br4923 DPGTRADPFPVYRALIDYGPMQLPGMPLTVFSSFSDCDEALRHPLSASDR
* : .:* .. .. .
Mb3575c|M.bovis_AF2122/97 VIPRFKND---IAREDIEVQRFVMLNMDAPHHTRLRKIISRGFTPRAVGR
Rv3545c|M.tuberculosis_H37Rv VIPRFKND---IAREDIEVQRFVMLNMDAPHHTRLRKIISRGFTPRAVGR
Mflv_5053|M.gilvum_PYR-GCK LLVTAEADDLGKSQQEAGIGLRTLIHMDDPHHRKVRAIGADWFRPKAMRD
Mvan_1301|M.vanbaalenii_PYR-1 VLVTAEADDMARAQLEAGFGLRTLIHMDDPHHRKVRAIGADWFRPKAMRD
MSMEG_1429|M.smegmatis_MC2_155 LLATAEADDLGRSQQEMGIGLRTLIHMDDPHHRKVRAIGADWFRPKAMRE
TH_3764|M.thermoresistible__bu LLATAEADDLAKAQLEAGMGLRTLIHMDDPHHRDVRKIGADWFRPKAMRD
MMAR_3999|M.marinum_M VLATVAGD-----ELQAAAGVRTLIHLDDPQHRVARAIGADWFRPKAMRA
MUL_3863|M.ulcerans_Agy99 VLATVAGD-----ELQAAAGVRTLIHLDDPQHRVARAIGADWFRPKAMRA
MAV_1609|M.avium_104 VLTTAEGD-----EMQAAAGVRTLIHMDDPQHRVVRAIGSDWFRPKAMRA
MAB_3825|M.abscessus_ATCC_1997 LLMNLEQEAELDKQAAMGIELKTLVHIDDPKHRVLRAIGADWFRPKAMRD
MLBr_02088|M.leprae_Br4923 LKATLAQQAIAAGAEPRPFYASSFMFLDPPDHTRLRKLVSKAFAPKVVQA
: : :: :* *.* * : : * *:.:
Mb3575c|M.bovis_AF2122/97 LHDELQERAQKIAAEAAAAG-SGDFVEQVSCELPLQAIAGLLGVPQEDRG
Rv3545c|M.tuberculosis_H37Rv LHDELQERAQKIAAEAAAAG-SGDFVEQVSCELPLQAIAGLLGVPQEDRG
Mflv_5053|M.gilvum_PYR-GCK LKVRVDELAKRYVDRMRDIGPECDFVTEIAVNFPLYVILSLLGLPEEDFG
Mvan_1301|M.vanbaalenii_PYR-1 LKIRVDELAKRYVDKMRDIGPECDFVTEIAVNFPLYVILSLLGLPEEDFG
MSMEG_1429|M.smegmatis_MC2_155 LKVRVDELARIYVDKMREIGPECDFVTDIAVNFPLYVILSLLGLPEEDFG
TH_3764|M.thermoresistible__bu LKVRVDELARRYVDKMVEIGPECDFVDDIAVYYPLYVIMSLLGLPEEDFP
MMAR_3999|M.marinum_M LKVRVDELAKNYVDAMMAAGPECDFVQQIAVNYPLYVIMSLLGLPEADFP
MUL_3863|M.ulcerans_Agy99 LKVRVDELAKNYVDAMMAAGPECDFVQQIAVNYPLYVIMSLLGLPEADFP
MAV_1609|M.avium_104 LKVRVDELAKIYVDKMLAAGPECDFVQEVAVNYPLYVIMSLLGLPEADFP
MAB_3825|M.abscessus_ATCC_1997 MKLRTDELANRYVNKLLEAGGSCDFAQDIAVHFPLYVIMSLLGIPESDFD
MLBr_02088|M.leprae_Br4923 LEGDIAALVDSLLDKGAAAG-QFDVIADLAFPLAVAVICRLLGVPYEDAP
:. . * . *. ::: .: .* ***:* *
Mb3575c|M.bovis_AF2122/97 KLFHWSNEMTGNEDPEYAH--------IDPKASSAELIGYAMKMAEEKAK
Rv3545c|M.tuberculosis_H37Rv KLFHWSNEMTGNEDPEYAH--------IDPKASSAELIGYAMKMAEEKAK
Mflv_5053|M.gilvum_PYR-GCK RMHMLTQEMFGGDD-EYKRGTTP----EEQLAVLTDFFNYFAALTASRRE
Mvan_1301|M.vanbaalenii_PYR-1 RMHMLTQEMFGGDDDEYKRGATV----EEQMAVLTDFFNYFGALTASRRA
MSMEG_1429|M.smegmatis_MC2_155 RMHMLTQEMFGGDDDEYKRGTTV----EEQMAVLTDFFNYFSALTNSRRE
TH_3764|M.thermoresistible__bu RMLRLTQELFGGDEEEYKRGTTP----EEQLQVLMDFFNYFNELTIARRK
MMAR_3999|M.marinum_M RMLKLTQELFGSDDSEFKRGSTS----EDQLPALLDMFGYFNAVTTARRE
MUL_3863|M.ulcerans_Agy99 RMLKLTQELFGSDDSEFKRGSTS----EDQLPALLDMFGYFNAVTTARRA
MAV_1609|M.avium_104 RMLKLTQELFGSDDSEFKRGSSN----EDQLPALLDMFGYFNGVTAARRE
MAB_3825|M.abscessus_ATCC_1997 RMLKLTQELFGGDDSEFQRGTTP----EEQLMALLDFFGYFSGLTASRRQ
MLBr_02088|M.leprae_Br4923 EFGRVSALLVQSVDPFITITGEPPEATEERLRAGVWLRDYLEQLVKCRRG
.: : : . : : : .* :. :
Mb3575c|M.bovis_AF2122/97 NPADDIVTQLIQADIDGEKLSDDEFGFFVVMLAVAGNETTRNSITQGMMA
Rv3545c|M.tuberculosis_H37Rv NPADDIVTQLIQADIDGEKLSDDEFGFFVVMLAVAGNETTRNSITQGMMA
Mflv_5053|M.gilvum_PYR-GCK HPTEDLASAIANGLVDGEPMSDMDTLSYYVIVASAGHDTTKDAISGGLHA
Mvan_1301|M.vanbaalenii_PYR-1 NPTDDLASAIANGLVDGELMSDVDTLSYYVIVASAGHDTTKDAISGGLHA
MSMEG_1429|M.smegmatis_MC2_155 NPTDDLASAIANGRVDGELMSDMDTLSYYVIVASAGHDTTKDAISGGLHA
TH_3764|M.thermoresistible__bu NPTDDLASAIANGRINGELLSDVDCLSYYVIVATAGHDTTSHAISDGLRA
MMAR_3999|M.marinum_M HPTEDLASAIANARIDGEPLSDIDTVSYYLIVATAGHDTTSATISGGLHA
MUL_3863|M.ulcerans_Agy99 HPTADLASAIANARIDGEPLSDIDTVSYYLIVATAGHDTTSATISGGLHA
MAV_1609|M.avium_104 HPTEDLASAIANARVDGEPLSDIDTVSYYLIVATAGHDTTSATISGGLQA
MAB_3825|M.abscessus_ATCC_1997 HPTDDLASTIANARVDGELLSDVDTASYYTIIATAGHDTTSATIAGGLEA
MLBr_02088|M.leprae_Br4923 TPGEDLISRLIELDESGDQLTEEEIIATCGLLLVAGHETTVNLIANAVLA
* *: : : : .*: ::: : :: **::** *: .: *
Mb3575c|M.bovis_AF2122/97 FAEHPDQWELYKKVR--PETAADEIVRWATPVTAFQRTALRDYELSGVQI
Rv3545c|M.tuberculosis_H37Rv FAEHPDQWELYKKVR--PETAADEIVRWATPVTAFQRTALRDYELSGVQI
Mflv_5053|M.gilvum_PYR-GCK LIENPGELARLKGDLSLMPTAVEEMIRWSTPVKEFMRTAAEDTTVRGVPI
Mvan_1301|M.vanbaalenii_PYR-1 LVENPGELARLQGDLDLMPTAVEEMIRWSTPVKEFMRTAAEDTTVRGVPI
MSMEG_1429|M.smegmatis_MC2_155 LIENPGELARLKADPGLMGTAVEEMIRWSTPVKEFMRTAAEDTEVRGVPI
TH_3764|M.thermoresistible__bu LIENPDQLERLKADPALMPTAVEEMIRWSTPVKEFMRTAAADTEVRGVPI
MMAR_3999|M.marinum_M LIEHPDQLARLQADPALIPLATEEMIRWVTPVKQFMRTASRDTVVRGIPI
MUL_3863|M.ulcerans_Agy99 LIEHPDQLARLQADPALMSLATEEMIRWVTPVKQFMRTASSDTVVRGIPI
MAV_1609|M.avium_104 LIENPDQLQRLRDNLDLMPLATEEMIRWVTPVKEFMRTAAKDTVVRGVPI
MAB_3825|M.abscessus_ATCC_1997 LLEHPDQLARLRENPGLMPLAVDEMIRWVTPVKEFMRTATADTEIRGVPI
MLBr_02088|M.leprae_Br4923 MLRNPSQWKALSSNPQRAPLVVEETLRYDPAIHLIGRVAAKDMTIGQTTL
: .:*.: ..:* :*: ..: : *.* * : :
Mb3575c|M.bovis_AF2122/97 KKGQRVVMFYRSANFDEEVFQDPFTFNILRNPNPHVGFGGTGAHYCIGAN
Rv3545c|M.tuberculosis_H37Rv KKGQRVVMFYRSANFDEEVFQDPFTFNILRNPNPHVGFGGTGAHYCIGAN
Mflv_5053|M.gilvum_PYR-GCK AKGESVYLAYVSANRDEEVFADPFRFDVGRDPNKHLAFG-YGVHFCLGAA
Mvan_1301|M.vanbaalenii_PYR-1 AKGESVYLAYVSANRDEDIFDDPFRFDVGRDPNKHLSFG-YGVHFCLGAA
MSMEG_1429|M.smegmatis_MC2_155 AKGESVYLAYVSGNRDEEVFTDPFRFDVGRDPNKHLAFG-YGVHFCLGAA
TH_3764|M.thermoresistible__bu KAGESVYLSYVSANFDEEVFDEPFRXXX-------------------STA
MMAR_3999|M.marinum_M AAGESVLLSYVSANRDEEVFDQPFRFDIGREPNKHVAFG-YGVHFCMGAA
MUL_3863|M.ulcerans_Agy99 AAGESVLLSYVSANRDEEVFDQPFRFDIGREPNKHVAFG-YGVHFCMGAA
MAV_1609|M.avium_104 AAGESVLLSYVSANRDEDVFDEPFRFDVGRDPNKHLAFG-YGVHFCMGAA
MAB_3825|M.abscessus_ATCC_1997 TEGESVLLSYPSGNRDEDIFTDPFTFDIARDPNKHLAFG-FGVHFCLGAA
MLBr_02088|M.leprae_Br4923 TEGDTMVLLLAAANRDPAVYSRPDEFDPDRPSSRHLAFA-VGSHFCLGAA
*: : : :.* * :: * .:
Mb3575c|M.bovis_AF2122/97 LARMTINLIFNAVADHMPDLKPISAPERLRSGWLNGIKHWQVDYTGRCPV
Rv3545c|M.tuberculosis_H37Rv LARMTINLIFNAVADHMPDLKPISAPERLRSGWLNGIKHWQVDYTGRCPV
Mflv_5053|M.gilvum_PYR-GCK LARMEINSLFTELLPRLDSIELAGEAELSATTFVGGLKHLPVRYSLR---
Mvan_1301|M.vanbaalenii_PYR-1 LARMEINSLFSELLPRLDSIELAGRPELSATTFVGGLKHLPVRYSLR---
MSMEG_1429|M.smegmatis_MC2_155 LARMEMNSLFSELLPRLDSIELAGEPELSATTFVGGLKHLPIRYSIR---
TH_3764|M.thermoresistible__bu --------------------------------------------------
MMAR_3999|M.marinum_M LARMEVGSFFTELLPRLKSIELSGDPQFTATTFVGGLKHLPVSYSLV---
MUL_3863|M.ulcerans_Agy99 LARMEVASFFTELLPRLKSIELSGDPQFTATTFVGGLKRLPVSYSLM---
MAV_1609|M.avium_104 LARMEVNSFFTELLPRLKSIELTGDPELVATTFVGGLKHLPVRYSLA---
MAB_3825|M.abscessus_ATCC_1997 LARMEVNSFFSALLPRLESIEVDGNIERTSTIFVGGIKHLPIRYTLR---
MLBr_02088|M.leprae_Br4923 LARLEATVTLSAISARFPQVQLAGELVYKPNVAMRGMSALPVQV------
Mb3575c|M.bovis_AF2122/97 AH
Rv3545c|M.tuberculosis_H37Rv AH
Mflv_5053|M.gilvum_PYR-GCK --
Mvan_1301|M.vanbaalenii_PYR-1 --
MSMEG_1429|M.smegmatis_MC2_155 --
TH_3764|M.thermoresistible__bu --
MMAR_3999|M.marinum_M --
MUL_3863|M.ulcerans_Agy99 --
MAV_1609|M.avium_104 --
MAB_3825|M.abscessus_ATCC_1997 --
MLBr_02088|M.leprae_Br4923 --