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M. thermoresistible (build 8) TH_3763 (-)

annotation: Cyclopropane-fatty-acyl-phospholipid synthase
coordinates: 3754619 - 3755494
length: 292

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3763--100% (292)Cyclopropane-fatty-acyl-phospholipid synthase
M. thermoresistible (build 8)TH_2621-e-10964.11% (287) PUTATIVE methoxy mycolic acid synthase 1
M. thermoresistible (build 8)TH_3139-2e-9761.48% (283) PUTATIVE Cyclopropane-fatty-acyl-phospholipid synthase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0478umaA11e-12171.83% (284) mycolic acid synthase
M. gilvum PYR-GCKMflv_1800-1e-10160.98% (287) cyclopropane-fatty-acyl-phospholipid synthase
M. tuberculosis H37RvRv0469umaA1e-12171.83% (284) mycolic acid synthase
M. leprae Br4923MLBr_01900mmaA11e-11267.02% (285) methyl mycolic acid synthase 1
M. abscessus ATCC 19977MAB_4088c-1e-12171.18% (288) mycolic acid synthase UmaA1
M. marinum MMMAR_0794umaA1e-12675.00% (284) mycolic acid synthase UmaA
M. avium 104MAV_4680-1e-12374.20% (283) methoxy mycolic acid synthase 1
M. smegmatis MC2 155MSMEG_0913-1e-12773.10% (290) methoxy mycolic acid synthase 1
M. ulcerans Agy99MUL_4538umaA1e-12674.65% (284) mycolic acid synthase UmaA
M. vanbaalenii PYR-1Mvan_0803-1e-13176.29% (291) cyclopropane-fatty-acyl-phospholipid synthase

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_0913|M.smegmatis_MC2_155      ---MSN--------------VESELAPYYEESQSIYDISNEFFALFLG-P
Mvan_0803|M.vanbaalenii_PYR-1       ---MSN--------------AVPDLSPYYEESQSIYDVSNEFFALFLG-P
MAB_4088c|M.abscessus_ATCC_199      ---MS------------------DLKPYYEESQSIYDISDEFYGLFLDEE
Mb0478|M.bovis_AF2122/97            ---MT------------------ELRPFYEESQSIYDVSDEFFSLFLD-P
Rv0469|M.tuberculosis_H37Rv         ---MT------------------ELRPFYEESQSIYDVSDEFFSLFLD-P
MMAR_0794|M.marinum_M               ---MT------------------ELRPFYEESQSIYDVSDEFFALFLD-P
MUL_4538|M.ulcerans_Agy99           ---MT------------------ELRPFYEESQSIYDVSDEFFALFLD-P
MAV_4680|M.avium_104                MPRMT------------------GLEPYYEESQSIYDVSDEFFALFLD-P
MLBr_01900|M.leprae_Br4923          ---MA------------------KLRPYYEESQSAYDISDDFFALFLD-P
TH_3763|M.thermoresistible__bu      ---MTN--------------TSAELEPFFEESQSIYDVSDDFFALFLG-P
Mflv_1800|M.gilvum_PYR-GCK          ---MTGRTAEPPTGHDTTPPTAEDMKPHFEEVQAHYDLSDVFFGLFQD-P
                                       *:                   : *.:** *: **:*: *:.** .  

MSMEG_0913|M.smegmatis_MC2_155      TMGYTCGYYEREDMTLDESQNAKFDLALGKLDLKPGMTLLDVGCGWGGAL
Mvan_0803|M.vanbaalenii_PYR-1       TMGYTCSYFEREDMTLDEAQIAKFDLALGKLNLEPGMTLLDVGCGWGGAL
MAB_4088c|M.abscessus_ATCC_199      TMGYTCAYFERDDLTLAEAQIAKFDLALGKLNLEPGMTVLDIGCGWGACL
Mb0478|M.bovis_AF2122/97            TMAYTCAYFEREDMTLEEAQNAKFDLALDKLHLEPGMTLLDIGCGWGGGL
Rv0469|M.tuberculosis_H37Rv         TMAYTCAYFEREDMTLEEAQNAKFDLALDKLHLEPGMTLLDIGCGWGGGL
MMAR_0794|M.marinum_M               TMAYTCAYFERDDMTLEEASNAKFDLALGKLNLEPGMTLLDIGCGWGGAL
MUL_4538|M.ulcerans_Agy99           TMAYTCAYFERDDMTLEEASNAKFDLALGKLNLEPGMTLLDIGCGWGGAL
MAV_4680|M.avium_104                TMAYTCAFFERDDMTLEEAQTAKFDLALGKLNLEPGMTLLDIGCGWGGAL
MLBr_01900|M.leprae_Br4923          TWVYTCAYFERDDMTLEEAQLAKLDLALDKLNLAPGMTLLDVGCGWGGAL
TH_3763|M.thermoresistible__bu      TMGYTCAYFERDDMTLDEAQIAKFDLALGKLNLEPGMTLLDIGCGWGGAL
Mflv_1800|M.gilvum_PYR-GCK          SRTYSCAYYERDDMTLAEAQIAKIDLALGKLNLEPGMTLLDIGCGWGSVL
                                    :  *:*.::**:*:** *:. **:****.**.* ****:**:*****. *

MSMEG_0913|M.smegmatis_MC2_155      ERAVTKYDVNVIGITLSKAQSDYARERLAKI--ETNRSVEVRLQGWEEFN
Mvan_0803|M.vanbaalenii_PYR-1       RRAVEKYDVNVIGITLSRKQFEYSKALMAGL--DTERKAEVRLQGWEEFD
MAB_4088c|M.abscessus_ATCC_199      DRAMRKFDVNVIGITLSKNQSEYSRKRLAQVAAETGRSAEIRMQGWEEFN
Mb0478|M.bovis_AF2122/97            QRAIENYDVNVIGITLSRNQFEYSKAKLAKIP--TERSVQVRLQGWDEFT
Rv0469|M.tuberculosis_H37Rv         QRAIENYDVNVIGITLSRNQFEYSKAKLAKIP--TERSVQVRLQGWDEFT
MMAR_0794|M.marinum_M               QRAVEKYDVNVIGITLSRNQFEYSKAKMAKIP--TERTVEVRLQGWEEFE
MUL_4538|M.ulcerans_Agy99           QRAVEKYDVNVIGITLSRNQFDYSKAKMAKIP--TERTVEVRLQGWEEFE
MAV_4680|M.avium_104                KRALEKYDVNVIGITLSRNQFEYSKKLLAGFP--TDRNIEVRLQGWEEFD
MLBr_01900|M.leprae_Br4923          VRAVEKYDVNVIGLTLSRNHCARSKARLAEIL--TKRHAEARLQGWEEFE
TH_3763|M.thermoresistible__bu      QLALEKYDVNVIGITLSRNQYEYSKARLAQID--TARTAEVRLQGWEQFD
Mflv_1800|M.gilvum_PYR-GCK          QRAVEKYDVNVVGLTLSRNQCKFAQDLLDGLD--TERSRRILLRGWEQFD
                                      *: ::****:*:***: :   ::  :  .   * *  .  ::**::* 

MSMEG_0913|M.smegmatis_MC2_155      EPVDRIVSIGAFEAFKAERYPVFFERAYSILPDDGRMLLHTILAHTQKFF
Mvan_0803|M.vanbaalenii_PYR-1       EPVDRIVSIGAFEAFKAERYPLFFERAYDILPADGRMLLHTILAHTQKFF
MAB_4088c|M.abscessus_ATCC_199      DKVDRIVTIGAFEAFKQERYPIFFERAYDILPNDGRMLLHTILAHTQQFF
Mb0478|M.bovis_AF2122/97            DKVDRIVSIGAFEAFKMERYAAFFERSYDILPDDGRMLLHTILTYTQKQM
Rv0469|M.tuberculosis_H37Rv         DKVDRIVSIGAFEAFKMERYAAFFERSYDILPDDGRMLLHTILTYTQKQM
MMAR_0794|M.marinum_M               DKVDRIVTIGAFEAFKMERYAAFFERSYDILPDDGRMLLHTILTYTQKQF
MUL_4538|M.ulcerans_Agy99           DKVDRIVTIGAFEAFKMERYAAFFERSYDILPDDGRMLLHTILTYTQKQF
MAV_4680|M.avium_104                DKVDRIVTIGAFEAFKMERYSAFFDRAYDILPDDGRMLLHTILTYTQKQQ
MLBr_01900|M.leprae_Br4923          EKVDRIVSFEALDAFKKERYPAFFERSYNILPDDGRMLLHSLFTYDRRWL
TH_3763|M.thermoresistible__bu      EPVDRIVSIGAFEAFKKPRYAAFFEMAHKALPADGRMLLHTILAHPQTYF
Mflv_1800|M.gilvum_PYR-GCK          EPVDRIISIEAIEAFPQERYAPFFKMCSSVLPEGGRFVLQAILGHPLKKW
                                    : ****::: *::**   **. **. . . ** .**::*:::: :     

MSMEG_0913|M.smegmatis_MC2_155      RENGIKLTISDLKFMKFIGEEIFPGGQLPAVEDIEKLAADSGFKLERIHL
Mvan_0803|M.vanbaalenii_PYR-1       RDNGIKLTISDLKFMRFIGTEIFPGGQLPAVEDIEKLAADSGFTLERAHL
MAB_4088c|M.abscessus_ATCC_199      RENGIAITISDLKFMKFIGEEIFPGGQLPAVEDIEKLAADSGFNLERVHL
Mb0478|M.bovis_AF2122/97            HEMGVKVTMSDVRFMKFIGEEIFPGGQLPAQEDIFKFAQAADFSVEKVQL
Rv0469|M.tuberculosis_H37Rv         HEMGVKVTMSDVRFMKFIGEEIFPGGQLPAQEDIFKFAQAADFSVEKVQL
MMAR_0794|M.marinum_M               HEMGVKVTMSDVRFMRFIGQEIFPGGQLPAQEDIFNFAQAAGFSVERAQL
MUL_4538|M.ulcerans_Agy99           HEMGVKVTMSDVRFMRFIGQEIFPGGQLPAQEDIFNFAQAAGFSVERAQL
MAV_4680|M.avium_104                HERGVSITMSDLRFMRFIGQEIFPGGQLPAQEDIFKFGEAAGFSVERVQL
MLBr_01900|M.leprae_Br4923          HEQGIPLTMGDLRFLKFLRESIFPGGELPSQPDIVDNAEAAGFSVEQIQL
TH_3763|M.thermoresistible__bu      REAGIKITISDLKFMQFIGREIFPGGELPAEGDVVEFATGAGFSVERIQL
Mflv_1800|M.gilvum_PYR-GCK          PELGIPIVMSDLKFMRFIAKEIFPGGSVPGEENIVELSAEAGFTLEQTQF
                                     : *: :.:.*::*::*:  .*****.:*.  :: . .  :.*.:*: ::

MSMEG_0913|M.smegmatis_MC2_155      LQPHYARTLDMWAANLEAKKDEAIAMQGQEVYDRYMKYLTGCADFFRRGI
Mvan_0803|M.vanbaalenii_PYR-1       LRPHYARTLDMWAANLEANRQEATRITSPEVYERYMHYLTGCADFFRRGI
MAB_4088c|M.abscessus_ATCC_199      LQPHYAKTLDIWAQNLEQRREEAIAIQSQEVYDRFMKYLTGCADFFRRGV
Mb0478|M.bovis_AF2122/97            LQQHYARTLNIWAANLEANKDRAIALQSEEIYNKYMHYLTGCEHFFRKGI
Rv0469|M.tuberculosis_H37Rv         LQQHYARTLNIWAANLEANKDRAIALQSEEIYNKYMHYLTGCEHFFRKGI
MMAR_0794|M.marinum_M               LQQHYARTLNIWAANLEARKEEAIAMQSQEIYDKYMHYLTGCENFFRKGI
MUL_4538|M.ulcerans_Agy99           LQQHYARTLNIWAANLEARKEEAIAMQSQEIYDKYMHYLTGCENFFRKGI
MAV_4680|M.avium_104                LREHYARTLNIWAANLEANKDKAIAIQSQAVYDRYMHYLTGCENFFRKGI
MLBr_01900|M.leprae_Br4923          MQPHYARTLDMWATNLAAARDHALAIQPEEIYDNFMHYLTGCADRFRRGL
TH_3763|M.thermoresistible__bu      LRPHYARTLDIWAENLAANREPAIAMQSEEVYDRYYRYLTGCADFFRRGI
Mflv_1800|M.gilvum_PYR-GCK          LNKDYARTLDTWAEALEAHHDEAVAATSEEVYQRYMKYLTGCSDFFTRGI
                                    :. .**:**: **  *   :: *       :*:.: :***** . * :*:

MSMEG_0913|M.smegmatis_MC2_155      TNVGQFTLVK-
Mvan_0803|M.vanbaalenii_PYR-1       TNVGQFTLVKG
MAB_4088c|M.abscessus_ATCC_199      TNVGQFTLVK-
Mb0478|M.bovis_AF2122/97            SNVGQFTLTK-
Rv0469|M.tuberculosis_H37Rv         SNVGQFTLTK-
MMAR_0794|M.marinum_M               SNVGQFTLVK-
MUL_4538|M.ulcerans_Agy99           SNVGQFTLVK-
MAV_4680|M.avium_104                SNVGQFTLVK-
MLBr_01900|M.leprae_Br4923          INVAQFTLTK-
TH_3763|M.thermoresistible__bu      TNVGQFTLTKG
Mflv_1800|M.gilvum_PYR-GCK          SELGQFTLVKA
                                     ::.****.*