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M. thermoresistible (build 8) TH_3736 (-)

annotation: acyl-CoA dehydrogenase domain protein
coordinates: 21592 - 22845
length: 418

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_3736 - - 100% (418) acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8) TH_3837 - 1e-62 37.43% (382) PUTATIVE Butyryl-CoA dehydrogenase
M. thermoresistible (build 8) TH_3604 - 1e-60 36.94% (379) PUTATIVE putative acyl-CoA dehydrogenase domain protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0221c fadE3 3e-65 38.68% (380) acyl-CoA dehydrogenase FADE3
M. gilvum PYR-GCK Mflv_4370 - 0.0 83.58% (402) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv0752c fadE9 5e-60 36.58% (380) acyl-CoA dehydrogenase FADE9
M. leprae Br4923 MLBr_00737 fadE25 5e-53 33.16% (380) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_1188c - 2e-58 36.05% (380) acyl-CoA dehydrogenase
M. marinum M MMAR_4034 fadE 0.0 83.63% (391) acyl-CoA dehydrogenase FadE
M. avium 104 MAV_1571 - 0.0 84.36% (390) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_2205 - 0.0 87.47% (391) putative acyl-CoA dehydrogenase
M. ulcerans Agy99 MUL_4024 fadE3 9e-59 35.79% (380) acyl-CoA dehydrogenase FadE3
M. vanbaalenii PYR-1 Mvan_1974 - 0.0 87.69% (390) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0221c|M.bovis_AF2122/97           -MRN-------------------------ELNDDEAMLVATVRAFIDRDV
MUL_4024|M.ulcerans_Agy99           MMNND--------------------SPDSQLDEDEAMLVATVRAFIDRDV
TH_3736|M.thermoresistible__bu      -MYDIRRPGGVAIAPPGRTHKEKPMSTAEVSDEDFRQILRQTREFVRTAV
MSMEG_2205|M.smegmatis_MC2_155      -MTGTVTDG---------------QSAAEVGDEDFEEILAQARSFIRNAV
Mflv_4370|M.gilvum_PYR-GCK          -MASPPANAAEAG-----------IPSAEVNDEDFQAILAATREFVRTAV
Mvan_1974|M.vanbaalenii_PYR-1       ------------------------MSTAEVGDEDFRQILAQTRQFVRTAV
MMAR_4034|M.marinum_M               -MT-----------------------APQVSDEDFAQILAQTRHFVRSVV
MAV_1571|M.avium_104                -MTSA--------------------EVAEVSEQDFGEILAQTRQFVRTAV
Rv0752c|M.tuberculosis_H37Rv        ---------------------------MFVLNDDERVIVETAAAFAGKRL
MAB_1188c|M.abscessus_ATCC_199      ---------------------------MFNLTEEQREIWNTAREFADIHI
MLBr_00737|M.leprae_Br4923          ----------------MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEI
                                                                    ::   :      :    :

Mb0221c|M.bovis_AF2122/97           KPTVREVEHANSYPEAWIEQMKHIGIYGLAIDEQYGGSPVSMPCYVQVTQ
MUL_4024|M.ulcerans_Agy99           RPSVREVEHANTYPQAWIEQMKRIGIYGLAIGEAYGGSPVSMPCYVQVTQ
TH_3736|M.thermoresistible__bu      VPRELEILNEDRVPDDLREQAKQMGLFGYAIPQQWGGLGLDLAQDVELAM
MSMEG_2205|M.smegmatis_MC2_155      VPRENEILATDKVPDDIREQAKNMGLFGYAIPQQWGGLGLNLAQDVELAM
Mflv_4370|M.gilvum_PYR-GCK          VPREQEILSTDQVPDDLREQTKSMGLFGYAIPQEWGGLGLNLAQDVELAM
Mvan_1974|M.vanbaalenii_PYR-1       VPREQEILTTDRVPDELREQAKSMGLFGYAIPQEWGGLGLDLTQDVELAM
MMAR_4034|M.marinum_M               LPREQQILDEDRVPEDLRDQAKQMGLFGYAIPPQWGGLGLNLVQDVELAM
MAV_1571|M.avium_104                VPREQEILDGDRVPDDLRDQAKKMGLFGYAIPQQWGGLGLNLMQDVELAM
Rv0752c|M.tuberculosis_H37Rv        APHALEWDAAKHFPVDVLREAAELGMAAIYCRDDVGGSGLRRLDGVRIFE
MAB_1188c|M.abscessus_ATCC_199      APHALDWDRDKYFPVEIFPKAAALGMGGIYVNPDVGGSGLTRLDASLIFE
MLBr_00737|M.leprae_Br4923          APHAADVDQRARFPEEALAALNASGFNAIHVPEEYGGQGADSVAACIVIE
                                     *   :       *          *: .       **          :  

Mb0221c|M.bovis_AF2122/97           ELARGWMSLAGAMGG-HTVVAKLLTLFGTEEQRRTYLPPMASGELRATMA
MUL_4024|M.ulcerans_Agy99           ELARGWMSLAGAMGG-HTVVAKLLMLFGTDEQKSTYLPAMATGELRATMA
TH_3736|M.thermoresistible__bu      ELGYTSLALRSMFGTNNGIAGQVLVGFGTEEQKARWLEPIASGEVVASFA
MSMEG_2205|M.smegmatis_MC2_155      EFGYTSLALRSMFGTNNGIAGQVLVGFGTDEQKQQWLEGIASGEVVASFA
Mflv_4370|M.gilvum_PYR-GCK          ELGYTSLALRSMFGTNNGIAGQVLVGYGTDEQKKTWLERIASGEIVASFA
Mvan_1974|M.vanbaalenii_PYR-1       ELGYTSLALRSMFGTNNGIAGQVLVGYGTDEQKSTWLERIASGEVVASFA
MMAR_4034|M.marinum_M               ELGYTSLAVRSMFGTNNGIAGQVLVGFGTDEQKARWLEPIASGDVVASFA
MAV_1571|M.avium_104                ELGYTSLALRSMFGTNNGIAGQVLVGFGTEAQKARWLEPMAAGDVVASFA
Rv0752c|M.tuberculosis_H37Rv        QLAIADPVTA-AFLSIHNMCAWMIDSFGTDEQRKDWIPRLATMGVIASYC
MAB_1188c|M.abscessus_ATCC_199      AMATGCSAVS-AFISIHNMAAWMIDEFGDEEQRRRWLPSMCTMETIGAYC
MLBr_00737|M.leprae_Br4923          EVARVDASAS-LIPAVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYA
                                     ..         :   : :    :   * :  :   :  :.:    .: .

Mb0221c|M.bovis_AF2122/97           LTEPGGGSDLQNMSTTALADGPEGSAGLLINGCKTWISNARRSGLFAVLC
MUL_4024|M.ulcerans_Agy99           LTEPGGGSDLQNMSTTAMADGPDQ---LLITGAKTWISNARRSGLIALLC
TH_3736|M.thermoresistible__bu      LTEPGAGSNPAGLRSRAVRDGSGADADWIINGQKRFITNAPVADLFVVFA
MSMEG_2205|M.smegmatis_MC2_155      LTEPGAGSNPAGLRTKAVRDGS----DWVINGQKRFITNAPTAGLFVVFA
Mflv_4370|M.gilvum_PYR-GCK          LTEPGAGSNPSGLRTKAVRDGDGPHSGWILNGQKRFITNAPNADLFVTFA
Mvan_1974|M.vanbaalenii_PYR-1       LTEPGAGSNPSGLRTKAVRDGDGSCSGWIINGQKRFITNAPNANLFVTFA
MMAR_4034|M.marinum_M               LTEPGAGSSPAGLRTKAVRDGD----DWLITGQKRFITNAPVADLFVVFA
MAV_1571|M.avium_104                LTEPGAGSNPAGLRTKAVADGD----NWVISGQKRFITNAPVANLFVVFA
Rv0752c|M.tuberculosis_H37Rv        LTEPGAGSDAGALSTRAVRHGSGKGGDYVLDGVKQFISGAAASDVYVVMA
MAB_1188c|M.abscessus_ATCC_199      LTEPECGSDAAALRTSAIRQGD----EYVLNGVKQFISGAGAADLYVVMA
MLBr_00737|M.leprae_Br4923          LSEREAGSDAASMRTRAKADGD----DWILNGFKCWITNGGKSTWYTVMA
                                    *:*   **.   : : *  .*       :: * * :*:..  :   . :.

Mb0221c|M.bovis_AF2122/97           KTDPNATPRHQGMSIVLVEPG-PGLTVSRDLPKLGYKGVESCELSFDNLR
MUL_4024|M.ulcerans_Agy99           KTDPHATPRHHGISIVLVEPG-PGLNISADLPKLGYKGVEACELSFDNYR
TH_3736|M.thermoresistible__bu      RSRP-ADERGAGIAVFLVPADAPGVEVGAKDAKMGQEGAWTADVTFTDVR
MSMEG_2205|M.smegmatis_MC2_155      RTRP-ADADGAGIAVFLVPADTPGVEVGPKDAKMGQEGAWTADVNFTDVR
Mflv_4370|M.gilvum_PYR-GCK          RSRP-ADDKGAGIAVFLVPADTPGVDIGAKDKKMGQEGAWTADVNFTDVE
Mvan_1974|M.vanbaalenii_PYR-1       RSRP-ADDKGAGIAVFLVPADTPGVEVGAKDKKMGQEGAWTADVNFTDVR
MMAR_4034|M.marinum_M               RTRP-ASDKSPGIAVFLVPAQSAGVEVGAKDAKMGQEGAWTADVSFTDVR
MAV_1571|M.avium_104                RTRP-ADDQGPGIAVFLVPADAAGVQIGAKDAKMGQEGAWTADVSFDDVR
Rv0752c|M.tuberculosis_H37Rv        RTGAE-GPR--GVSAFIVEKGTPGLSFGAPEAKMGWHAQPTAQVVLDGVR
MAB_1188c|M.abscessus_ATCC_199      RTGGP-GPR--GISTIVVPKGTPGLSFGAPERKMGWHAQPTAQVVFEDVR
MLBr_00737|M.leprae_Br4923          VTDPDKGAN--GISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCR
                                     :         *:: .:*     *. ..    *:* ..  : :: :   .

Mb0221c|M.bovis_AF2122/97           VPVSAILGG--AMGQGFSQMMKGLETGRIQVAARALGVATAALEDSLAYA
MUL_4024|M.ulcerans_Agy99           APTSAILGG--QPGQGFSQMMKGLETGRIQVAARALGVASAALDDALAYA
TH_3736|M.thermoresistible__bu      VPASALVGG--EEDIGYRAAMTSLARGRVHIAALAVGTAQRALDESVAYA
MSMEG_2205|M.smegmatis_MC2_155      VPAAALVGG--SEDVGYRAAMTSLARGRVHIAALAVGTAQRALDESVAYA
Mflv_4370|M.gilvum_PYR-GCK          VPDTALVGG--SEDLGYRAAMTSLARGRVHIAALAVGAAQRALDESVAYA
Mvan_1974|M.vanbaalenii_PYR-1       VPDAALVGG--SEDIGYRAAMTSLARGRVHIAALAVGAAQRALDESVTYA
MMAR_4034|M.marinum_M               VDDAALVGG--SEDIGYRAAMTSLARGRVHIAAIAVGAAQRALDESVAYA
MAV_1571|M.avium_104                VGGDALIGG--SEDIGYRAAMTSLARGRVHIAALAVGAAQRALDESVSYA
Rv0752c|M.tuberculosis_H37Rv        VPAEAMLGGADGEGAGFGIAMSGLNGGRLNIAACSLGGAQAAFDKAGAYV
MAB_1188c|M.abscessus_ATCC_199      VPVANRIG---EEGIGFTIAMRGLNGGRLNIASCSLGGARSALEKVIEYL
MLBr_00737|M.leprae_Br4923          IPGDRIIG---EPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYT
                                          :*     . *:   :  *   *  :.: ::* *  *::    * 

Mb0221c|M.bovis_AF2122/97           QQRESFGRPIWQHQAVGNYLADMATKLTAARQLTRYAAERYDSGQ-RCDM
MUL_4024|M.ulcerans_Agy99           QQRHSFGQPIWKHQAIGNYLADMATKLTAARQLTHYAAQRYDSGQ-RCDM
TH_3736|M.thermoresistible__bu      ASATQGGTPIGQFQLVQAMLADQQTGVMAGRALVRDAARKWVSGE-DRRV
MSMEG_2205|M.smegmatis_MC2_155      ATATQGGQPIGNFQLVQAMIADQQTGVMAGRALVRDAAQKWVTGE-DRRI
Mflv_4370|M.gilvum_PYR-GCK          ATATQGGTPIGDFQLVQAMLADQQTGVMAGRALVRDAARLWVTGQ-DRRI
Mvan_1974|M.vanbaalenii_PYR-1       ATATQGGTAIGDFQLVQAMLADQQTGVMAGRALVRETARQWVTGE-DRRI
MMAR_4034|M.marinum_M               STATQGGVTIGSFQLVQAMLADQQTGVLAGRALVRDAARMWVSGA-DRRI
MAV_1571|M.avium_104                STATQGGTPIGNFQLVQAMLADQQTEVLAGRALVREAARLWVTGE-DRRV
Rv0752c|M.tuberculosis_H37Rv        RDRQAFGGSLLDEPTVRFTLADMATGLQTSRMLLWRAASALDDDDADKVE
MAB_1188c|M.abscessus_ATCC_199      RTRKAFGEELIKFQALQFRLADMATELEAARTMVWRAAAAVTEGDPRAAE
MLBr_00737|M.leprae_Br4923          KDRKQFGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPDLGF
                                          *  :     :   :**    : :.* :   :*     .      

Mb0221c|M.bovis_AF2122/97           EAGMAKLFASEVAMEIALNAVRIHGGYGYSTEYDVERYFRDAPLMILGEG
MUL_4024|M.ulcerans_Agy99           EAGMAKLFASETAMEIALNAVRIHGGYGYSTEYDVERYFRDAPLMIVGEG
TH_3736|M.thermoresistible__bu      APSAAKLFCTEMAGQVADLAVQIHGGTGYMREVPVERIYRDVRLLRLYEG
MSMEG_2205|M.smegmatis_MC2_155      APSAAKLYCTEMAGTVADLAVQIHGGTGYMREVPVERIYREVRLLRLYEG
Mflv_4370|M.gilvum_PYR-GCK          APSAAKLFCTEMAGKVADLAVQIHGGSGYMREVPVERIYRDVRLLRLYEG
Mvan_1974|M.vanbaalenii_PYR-1       APSAAKLFCTEMAGKVADLAVQIHGGSGYMREVPVERIYRDVRLLRLYEG
MMAR_4034|M.marinum_M               APSAAKLFCTEMAGKVADLAVQIHGGSGYMRGVPVERIYRDVRLLRLYEG
MAV_1571|M.avium_104                APSAAKLYCTEMAGRVADLAVQVHGGSGYMRGVPVERIYRDVRLLRLYEG
Rv0752c|M.tuberculosis_H37Rv        LCAMAKRYVTDTCFEVADQALQLHGGYGYLREYGLEKIVRDLRVHRILEG
MAB_1188c|M.abscessus_ATCC_199      LCAMAKRIATDVGFTVANEALQLHGGYGYLAEYGIEKIVRDLRVHQILEG
MLBr_00737|M.leprae_Br4923          ISAASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFMRDAKITQIYEG
                                      . :*   ::    ::  *:::.** **     :*:  *:  :  : **

Mb0221c|M.bovis_AF2122/97           TNEIQRNVIAGQLVARGGI-------
MUL_4024|M.ulcerans_Agy99           TNEIQRNVIARQLIARGGI-------
TH_3736|M.thermoresistible__bu      TSEIQRLIIGGGLVKAAQRQTN----
MSMEG_2205|M.smegmatis_MC2_155      TSEIQRLIIGGGLVKAAQRQL-----
Mflv_4370|M.gilvum_PYR-GCK          TSEIQKLIIGGGLVKGAKGK------
Mvan_1974|M.vanbaalenii_PYR-1       TSEIQRLIIGGGLVKGAKAR------
MMAR_4034|M.marinum_M               TSEIQQLIIGSNLIKAANR-------
MAV_1571|M.avium_104                TSEIQRLIIGSNLVKAAQRATTTKER
Rv0752c|M.tuberculosis_H37Rv        TNEIMRLVIGRAEAARFRATV-----
MAB_1188c|M.abscessus_ATCC_199      TNEIMRVIVSRKLIEQGLPA------
MLBr_00737|M.leprae_Br4923          TNQIQRVVMSRALLR-----------
                                    *.:* : ::.

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_3736	-	-	100% (418)	acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)	TH_3837	-	1e-62	37.43% (382)	PUTATIVE Butyryl-CoA dehydrogenase
M. thermoresistible (build 8)	TH_3604	-	1e-60	36.94% (379)	PUTATIVE putative acyl-CoA dehydrogenase domain protein