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M. thermoresistible (build 8) TH_3707 (-)

annotation: oxidoreductase, short-chain dehydrogenase/reductase family protein
coordinates: 947631 - 948275
length: 215

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3707--100% (215)oxidoreductase, short-chain dehydrogenase/reductase family protein
M. thermoresistible (build 8)TH_2589-8e-1127.27% (143) PUTATIVE short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_4328-2e-0928.19% (149) PUTATIVE oxidoreductase, short chain dehydrogenase/reductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0561c-2e-7869.61% (204) short chain dehydrogenase
M. gilvum PYR-GCKMflv_0026-4e-8370.19% (208) short chain dehydrogenase
M. tuberculosis H37RvRv0547c-2e-7869.61% (204) short chain dehydrogenase
M. leprae Br4923MLBr_00862ephD8e-0624.06% (212) short chain dehydrogenase
M. abscessus ATCC 19977MAB_3947-3e-6455.30% (217) short chain dehydrogenase
M. marinum MMMAR_0894-1e-7567.66% (201) dehydrogenase
M. avium 104MAV_4597-2e-7970.05% (207) short chain dehydrogenase
M. smegmatis MC2 155MSMEG_1073-7e-8676.10% (205) short chain dehydrogenase
M. ulcerans Agy99MUL_0647-1e-7567.66% (201) short chain dehydrogenase
M. vanbaalenii PYR-1Mvan_0944-1e-8170.24% (205) short chain dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


TH_3707|M.thermoresistible__bu      --------------------------------------------------
MSMEG_1073|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0026|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0944|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0561c|M.bovis_AF2122/97           --------------------------------------------------
Rv0547c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0894|M.marinum_M               --------------------------------------------------
MUL_0647|M.ulcerans_Agy99           --------------------------------------------------
MAV_4597|M.avium_104                --------------------------------------------------
MAB_3947|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_00862|M.leprae_Br4923          MPATQSIHKVPHQFVESPDGVRLAIYQSGQPEGPAIVLVHGFPDSHVLWD
                                                                                      

TH_3707|M.thermoresistible__bu      --------------------------------------------------
MSMEG_1073|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0026|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0944|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0561c|M.bovis_AF2122/97           --------------------------------------------------
Rv0547c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0894|M.marinum_M               --------------------------------------------------
MUL_0647|M.ulcerans_Agy99           --------------------------------------------------
MAV_4597|M.avium_104                --------------------------------------------------
MAB_3947|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_00862|M.leprae_Br4923          GVVPLLAKRFRIVRYDNRGVGQSSVPKPVSAYTMTRFADDFAAVIDELSP
                                                                                      

TH_3707|M.thermoresistible__bu      --------------------------------------------------
MSMEG_1073|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0026|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0944|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0561c|M.bovis_AF2122/97           --------------------------------------------------
Rv0547c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0894|M.marinum_M               --------------------------------------------------
MUL_0647|M.ulcerans_Agy99           --------------------------------------------------
MAV_4597|M.avium_104                --------------------------------------------------
MAB_3947|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_00862|M.leprae_Br4923          DRPVHVLAHDWGSVGVWEYLSRSGASDRVASFTSVSGPSQDQLVDYILSG
                                                                                      

TH_3707|M.thermoresistible__bu      --------------------------------------------------
MSMEG_1073|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0026|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0944|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0561c|M.bovis_AF2122/97           --------------------------------------------------
Rv0547c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0894|M.marinum_M               --------------------------------------------------
MUL_0647|M.ulcerans_Agy99           --------------------------------------------------
MAV_4597|M.avium_104                --------------------------------------------------
MAB_3947|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_00862|M.leprae_Br4923          LRRPWRPRTFARAVSQLFRLTYMVLFSIPVLVPMVLWIALSSATIRRTMV
                                                                                      

TH_3707|M.thermoresistible__bu      --------------------------------------------------
MSMEG_1073|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0026|M.gilvum_PYR-GCK          ----------------------------------------MRSSRKSASE
Mvan_0944|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0561c|M.bovis_AF2122/97           --------------------------------------------------
Rv0547c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0894|M.marinum_M               --------------------------------------------------
MUL_0647|M.ulcerans_Agy99           --------------------------------------------------
MAV_4597|M.avium_104                --------------------------------------------------
MAB_3947|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_00862|M.leprae_Br4923          DNISTDQIHHSATLARDAAHSVKTYPANYFRAFSGRRRGKGVPVVNVPVQ
                                                                                      

TH_3707|M.thermoresistible__bu      --------------------------------------------------
MSMEG_1073|M.smegmatis_MC2_155      ----------------MSKHPL-RRLTDNLFLASMRP-------------
Mflv_0026|M.gilvum_PYR-GCK          VLLECEFGAGNRLRGVTSRNPL-RRLADQVVLTSMRP-------------
Mvan_0944|M.vanbaalenii_PYR-1       ---------------MTSRNPL-RRLADQVVLTSMRP-------------
Mb0561c|M.bovis_AF2122/97           ----------------MSKRPL-RWLTEQITLAGMRP-------------
Rv0547c|M.tuberculosis_H37Rv        ----------------MSKRPL-RWLTEQITLAGMRP-------------
MMAR_0894|M.marinum_M               ----------------MSKSPL-RRLTEQITLAGMRP-------------
MUL_0647|M.ulcerans_Agy99           ----------------MSKSPL-RRLTEQITLAGMRP-------------
MAV_4597|M.avium_104                ----------------MSKSPL-RRFADQLVLATMRP-------------
MAB_3947|M.abscessus_ATCC_1997      ----------------MSKNSFGKRVSTTLARAAMQPF------------
MLBr_00862|M.leprae_Br4923          LIVNTMDRYVRPYGYDATARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHD
                                                                                      

TH_3707|M.thermoresistible__bu      -----------------------VRADGR------ADQGLDAARX-----
MSMEG_1073|M.smegmatis_MC2_155      --------PVTDQLIQLRAARDAVDLTGKRVLITGASSGIGAAAARKFAE
Mflv_0026|M.gilvum_PYR-GCK          --------PILPALLN-RPTRETIELRGKRVLLTGASSGIGEAAAEKLAR
Mvan_0944|M.vanbaalenii_PYR-1       --------PILPALLN-RPNRETIELKGKRVLLTGASSGIGEAAAEKLAR
Mb0561c|M.bovis_AF2122/97           --------PISPQLLINRPAMQPVDLTGKRILLTGASSGIGAAATKQFGL
Rv0547c|M.tuberculosis_H37Rv        --------PISPQLLINRPAMQPVDLTGKRILLTGASSGIGAAATKQFGL
MMAR_0894|M.marinum_M               --------PIAPQLLVNRPPIKPVALDGKRVMITGASSGIGEAAAEQFAR
MUL_0647|M.ulcerans_Agy99           --------PIAPQLLVNRPPIKPVALDGKRVMITGASSGIGEAAAEQFAR
MAV_4597|M.avium_104                --------PMAPQVLVNRPLIKPVELAGKRVLLTGASSGIGEAAAEQFAR
MAB_3947|M.abscessus_ATCC_1997      --------PSLPLVRARLDPNYGAPIKGKRVLITGASSGIGEEAAYQFGK
MLBr_00862|M.leprae_Br4923          LADLVDGKQPSRALLRAQVGRSRDTFGDTLVSVTGAGSGIGRETALALAR
                                                               .       *..*:.         

TH_3707|M.thermoresistible__bu      -------------------------GGTGRALACDLTDLDAIDELVLKIE
MSMEG_1073|M.smegmatis_MC2_155      RGARVIVVARRAELLDEVAGGITASGGDAKARPCDLTDLDAIDALVAEIE
Mflv_0026|M.gilvum_PYR-GCK          RGATVVAVARRQDLLDELVTRIADAGGDARAHACDLSDLDAVDELVATVE
Mvan_0944|M.vanbaalenii_PYR-1       RGATVVAVARRGDLLDDLVARITDAGGRARAHACDLSDLDAIDALVATVE
Mb0561c|M.bovis_AF2122/97           HRAVVVAVARRKDLLDAVADRITGDGGTAMSLPCDLSDMEAIDALVEDVE
Rv0547c|M.tuberculosis_H37Rv        HRAVVVAVARRKDLLDAVADRITGDGGTAMSLPCDLSDMEAIDALVEDVE
MMAR_0894|M.marinum_M               QGATVIAVARRKDLLDAVADRITTSGGVAMSAPCDISDLDAVDALVADVE
MUL_0647|M.ulcerans_Agy99           QGATVIAVARRKDLLDAVADRITTSGGVAMSAPCDISDLDAVDALVADVE
MAV_4597|M.avium_104                EGARVVVVARRKDLLDALAEGITRAGGEAIAMPCDISDLDAADALVADVQ
MAB_3947|M.abscessus_ATCC_1997      LGAKVIVVARREDLLAEVAARIIAEGGEAEAIACDLSDLDAIDKLVETVN
MLBr_00862|M.leprae_Br4923          RGAEVVVSDIDEAAAKNTAAQIVASGGVAYAYALDVSDAAAVEAFAEQVS
                                                             ** . : . *::*  * : :.  :.

TH_3707|M.thermoresistible__bu      QDLGGVDILINNAGKSIRRPLAESLERWHDVERTMNLNYYAPLRLIRGLA
MSMEG_1073|M.smegmatis_MC2_155      SDHGGLDILVNNAGHSIRRPLADSLERWHDIERTMTLNYYSPLRLIRGFA
Mflv_0026|M.gilvum_PYR-GCK          KDLGGIDILVNNAGRSIRRPLEESLERWHDVERTMTLNYYGPLRLIRGLA
Mvan_0944|M.vanbaalenii_PYR-1       DELGGVDILVNNAGRSIRRPLEESLDRWHDVERTMTLNYYGPLRLIRGLA
Mb0561c|M.bovis_AF2122/97           KRIGGIDILINNAGRSIRRPLAESLERWHDVERTMVLNYYAPLRLIRGLA
Rv0547c|M.tuberculosis_H37Rv        KRIGGIDILINNAGRSIRRPLAESLERWHDVERTMVLNYYAPLRLIRGLA
MMAR_0894|M.marinum_M               NRLGGVDILINNAGRSIRRPLAESLQRWHDVERTMVLNYYGPLRLIRGLA
MUL_0647|M.ulcerans_Agy99           NRLGGVDILINNAGRSIRRPLAESLQRWHDVERTMVLNYYGPLRLIRGLA
MAV_4597|M.avium_104                QQLGGVDILINNAGRSIRRPLAESLERWHDVERTMVLNYYAPLRLIRGIA
MAB_3947|M.abscessus_ATCC_1997      EKHGGVDILVNNAGRSIRRKTYESLDRWHDAERTMQLNYFSPLRLIRGFA
MLBr_00862|M.leprae_Br4923          AKHGVPDIVVNNAGIGQAGRFLDTPP--EEFDRVLAVNLGGVVNCCRAFG
                                       *  **::**** .      ::    .: :*.: :*  . :.  *.:.

TH_3707|M.thermoresistible__bu      PGMRE----------TWGVLSEASPLFSVYNASKAALTAVSRVVETEWSQ
MSMEG_1073|M.smegmatis_MC2_155      PGMRERGAGHIINVSTWGVLSEASPLFSVYQASKAALSAVSRVIETEWGD
Mflv_0026|M.gilvum_PYR-GCK          PGMLARGDGHIINVSTWGVKTESPPLFGVYNASKAALSSVSRIIETEWSG
Mvan_0944|M.vanbaalenii_PYR-1       PGMLERGDGHVINVSTWGVKTESPPLFGVYNASKAALSSISRIMETEWAD
Mb0561c|M.bovis_AF2122/97           PGMLERGDGHIINVATWGVLSEASPLFSVYNASKAALSAVSRIIETEWGS
Rv0547c|M.tuberculosis_H37Rv        PGMLERGDGHIINVATWGVLSEASPLFSVYNASKAALSAVSRIIETEWGS
MMAR_0894|M.marinum_M               PGMLERGDGHIINVTTWGVLSEASPLFSVYNASKAALSAVSRTIETEWGR
MUL_0647|M.ulcerans_Agy99           PGMLERGDGHIINVTTWGVLSEASPLFSVYNASKAALSAVSRTIETEWGR
MAV_4597|M.avium_104                PGMIERGDGHIINVSTWGVLSEASPLFAVYNASKAALSTVSRVVETEWGD
MAB_3947|M.abscessus_ATCC_1997      PGMVERRSGHIINVATWGVLTDVVPQFAVYNASKAALSTVSRIVDAEYGK
MLBr_00862|M.leprae_Br4923          QRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCLRAELDA
                                      :            :  .       :..* :****   .*  : :*   

TH_3707|M.thermoresistible__bu      FGVHSTTLFYPLVKTPMIAPTREYDNLP----ALSAEEAADWMISAARYR
MSMEG_1073|M.smegmatis_MC2_155      GGVHSTTLYYPLVDTPMIKPTRAFDGLP----ALSADEAADWMITAARHR
Mflv_0026|M.gilvum_PYR-GCK          RGVHATTLYYPLVKTPMIAPTRAYDGLP----GLSADEAAGWIVTAARHR
Mvan_0944|M.vanbaalenii_PYR-1       RGVHSTTLYYPLVKTPMIAPTRAYDGLP----GLSAEEAAGWIITAARHR
Mb0561c|M.bovis_AF2122/97           QGVHSTTLYYPLVATPMIAPTKAYDGLP----ALTAAEAAEWMVTAARTR
Rv0547c|M.tuberculosis_H37Rv        QGVHSTTLYYPLVATPMIAPTKAYDGLP----ALTAAEAAEWMVTAARTR
MMAR_0894|M.marinum_M               GGVHSTTLYYPLVATPMIAPTKAYSGMP----ALTPQEAAEWMITAARTR
MUL_0647|M.ulcerans_Agy99           GGVHSTTLYYPLVATPMIAPTKAYSGMP----ALTPQEAAEWMITAARTR
MAV_4597|M.avium_104                KGVHSTTLYYPLVATPMIAPTKAYQGVP----ALTPEEAGRWMITAARTR
MAB_3947|M.abscessus_ATCC_1997      YNVHTTTLYFPLVRTPMIAPTEAYTNAA----ALTSAEAAEWMVLAARTR
MLBr_00862|M.leprae_Br4923          VGVGLTTICPGVIDTNIIQSTRIDTPTAKQERVRDRRGQLDMMFRLRRYG
                                     .*  **:   :: * :* .*.     .              :.   *  

TH_3707|M.thermoresistible__bu      PIQIAPRMAVTARALNVVAPGVVNAVMKRQRIQP-------VFV----
MSMEG_1073|M.smegmatis_MC2_155      PVQIAPRVAVGARALNAVAPGVVNAVMKRQSAQPDGVGRRPIFPAG--
Mflv_0026|M.gilvum_PYR-GCK          PVSIAPRIAVTAHAINSVAPGAVDTIMKRQRMQPRD------------
Mvan_0944|M.vanbaalenii_PYR-1       PVSIAPRIAVTAHAINSIAPAAVDTIMKRQRMQPKD------------
Mb0561c|M.bovis_AF2122/97           PVRIAPRVAVAVNALDSIGPRWVNALMQRRNEQLNP------------
Rv0547c|M.tuberculosis_H37Rv        PVRIAPRVAVAVNALDSIGPRWVNALMQRRNEQLNP------------
MMAR_0894|M.marinum_M               PVRIAPRIALMAKALNTLGPRWVNTLMQQRDDQLNDR-----------
MUL_0647|M.ulcerans_Agy99           PVRIAPRIALMAKALNTLGPRWVNTLMQQRDDQLNDR-----------
MAV_4597|M.avium_104                PVRIAPRMAIAAKALDTFGPRWVNAVMQRQTVQPNREAGA--------
MAB_3947|M.abscessus_ATCC_1997      VVRIAPRISVMSAATNAVAPDLVTRVARNGRETLG-------------
MLBr_00862|M.leprae_Br4923          PDKVADTILSAIKKNKPIRPVAPEAYALYGISRVLPQVLRSTARIRVI
                                       :*  :       . . *