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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_3700 | - | - | 100% (474) | MMPL domain protein |
M. thermoresistible (build 8) | TH_3087 | - | 2e-38 | 28.90% (474) | PUTATIVE MmpL11 |
M. thermoresistible (build 8) | TH_2203 | mmpL8 | 7e-37 | 31.78% (343) | PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0208c | mmpL11 | 3e-39 | 29.41% (476) | transmembrane transport protein MmpL11 |
M. gilvum PYR-GCK | Mflv_0224 | - | 0.0 | 75.69% (469) | MMPL domain-containing protein |
M. tuberculosis H37Rv | Rv0202c | mmpL11 | 3e-39 | 29.41% (476) | transmembrane transport protein MmpL11 |
M. leprae Br4923 | MLBr_02617 | - | 2e-35 | 27.00% (474) | hypothetical protein MLBr_02617 |
M. abscessus ATCC 19977 | MAB_0937c | - | 1e-35 | 35.32% (269) | MmpL family protein |
M. marinum M | MMAR_1673 | - | 1e-174 | 68.94% (470) | transmembrane transport protein |
M. avium 104 | MAV_3895 | - | 1e-174 | 68.67% (466) | MmpL family protein |
M. smegmatis MC2 155 | MSMEG_0763 | - | 0.0 | 74.89% (470) | antibiotic transporter |
M. ulcerans Agy99 | MUL_1909 | - | 1e-172 | 68.30% (470) | transmembrane transport protein |
M. vanbaalenii PYR-1 | Mvan_0683 | - | 0.0 | 75.85% (468) | MMPL domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_0224|M.gilvum_PYR-GCK ------------MSRRFSWVIALLVVLVSGALMGLLGGGDSSSQSPVAVP Mvan_0683|M.vanbaalenii_PYR-1 ------------MSRRYSWVVALLVVLLSGALMGLLGGGDSGSQSPLIVP MSMEG_0763|M.smegmatis_MC2_155 ------------MS-----WLAVLVVIISGGLMGVLSGGDSASQSPVAVP TH_3700|M.thermoresistible__bu -------------------------------------------------- MMAR_1673|M.marinum_M ---MVWDRLAAALAAKRSWLISVGVVALATVFMVLVGGNSAAGQAPQSVP MUL_1909|M.ulcerans_Agy99 ---MVWDRLAAALAAKRSWLISVGVVALATVFMVLVGGNSAAGQAPQSVP MAV_3895|M.avium_104 ---MVWERVAAAVTGPRSWLLAAVAVLAGVGVMALVGPNTAAGQAPQSLP MAB_0937c|M.abscessus_ATCC_199 MRRLADLVVRWPWVVIGAWVALAIALPLTFPSLTEMAEKHPLAILPADAP Mb0208c|M.bovis_AF2122/97 -----MMRLSRNLRRCRWLVFTGWLLALVPAVYLAMTQSGNLTGGGFEVA Rv0202c|M.tuberculosis_H37Rv -----MMRLSRNLRRCRWLVFTGWLLALVPAVYLAMTQSGNLTGGGFEVA MLBr_02617|M.leprae_Br4923 ------MRLSSYLRRFRWLVFTGWLLALVPAIYLAMTQSGKLTGGGFEVA Mflv_0224|M.gilvum_PYR-GCK ADSESARADAARAALPGGDQVPAILVVTRTDSAPLGPADLAAVDGARDRM Mvan_0683|M.vanbaalenii_PYR-1 PDAESARADAARAALPDGDQVPAILVVTRADAAPLTPADVAAANSARDRM MSMEG_0763|M.smegmatis_MC2_155 SDAESARADALRADFPGGDQAPAILVVTRADGAELGPDDIDAAAEARHRM TH_3700|M.thermoresistible__bu -------------------------------------------------- MMAR_1673|M.marinum_M ADAESAKVESELGRFPGGDRAPLILVVTRSDGTTLDAADRRAAQQAAQRM MUL_1909|M.ulcerans_Agy99 ADVESAKVESELGRFPGGDRAPLILVVTRSDGTTLDAADRRAAQQAAQRM MAV_3895|M.avium_104 QHSPSARITALAGQFPGGDRTPLIVVVSRADGAVLGPADLGAARAARDRA MAB_0937c|M.abscessus_ATCC_199 SSVTAKKMTEAFHESSNDDLLLVVFINENGLGKDDADSYRKVVDALRHDL Mb0208c|M.bovis_AF2122/97 GSQSLLVHDQLDAHYPDRGAPALALVAAPRPDASYQDIDN-AVALLRQIA Rv0202c|M.tuberculosis_H37Rv GSQSLLVHDQLDAHYPDRGAPALALVAAPRPDASYQDIDN-AVALLRQIA MLBr_02617|M.leprae_Br4923 GSQSLLVHDQLQEQYPDQGAVSLALVAAPRSDASYQDMND-AVALLRRIV Mflv_0224|M.gilvum_PYR-GCK L--AAAQS---GPAGPPVQVSDDGQAAVATVPMSSDLSGFDLTDTVTELR Mvan_0683|M.vanbaalenii_PYR-1 L--TVAGN---AAGGPPTQVSEDGQAAVATVPLSADLSGFALTDKVKEVR MSMEG_0763|M.smegmatis_MC2_155 S--DAP--------GPPMVVSDDGKAAISTVPLDATLSGFALTDEVKELR TH_3700|M.thermoresistible__bu -------------------------------------------------- MMAR_1673|M.marinum_M Q--AAAHPGANPRPAAPLIS-ADTKAAISVVPISANLSGLALNDAVKALR MUL_1909|M.ulcerans_Agy99 Q--ASAHPGANPRPAAPLIS-ADTKAAISVVPISANLSGLALNDAVKALR MAV_3895|M.avium_104 Q--AAAQPGAAP--AQPLTPSQDGKAALGVVPLSTTLSGLALNDAVSALR MAB_0937c|M.abscessus_ATCC_199 TNVVSVQDFIGTPELRKFLTSQDNKTWVLPVGLAGELGTPKAFESYNRVT Mb0208c|M.bovis_AF2122/97 SELPGVTEAPNPTQRPPQPDRPYVVSLRLDARNAGTSDVAKKLRDRIGVK Rv0202c|M.tuberculosis_H37Rv SELPGVTEAPNPTQRPPQPDRPYVVSLRLDARNAGTSDVAKKLRDRIGVK MLBr_02617|M.leprae_Br4923 SEFPGVSEVPNPTQLPPRPDRPYGVSLRLDDRNSVTSDVAKQLRTKVGIK Mflv_0224|M.gilvum_PYR-GCK GAATDGLPEG-LQAQVTGGPAFGADIANSFSGANFTLLAVTAAVVALLLI Mvan_0683|M.vanbaalenii_PYR-1 TAAADGLPGD-LRAQVTGGPAFGADIADSFSGANVTLLAVTAAVVALLLI MSMEG_0763|M.smegmatis_MC2_155 ANAAEGLPGD-LRAEVTGGPAFGADIANSFAGANVTLLAVTAIVVALLLI TH_3700|M.thermoresistible__bu -------------------------------------------------- MMAR_1673|M.marinum_M EAAHEGLPAD-LDAHVTGGPAFGADIANAFTNANITLLAVTASVVALLLI MUL_1909|M.ulcerans_Agy99 EAAHEGLPAD-LDAHVTGGPAFGADIANAFTNANITLLAVTASVVALLLI MAV_3895|M.avium_104 TAAATGLAAD-LQVHVTGGPAFGADIAGAFTHANVTLLAVTASVVALLLI MAB_0937c|M.abscessus_ATCC_199 SLIQHSIDGSPTTVHITGPAATVADLTVAGQQDRLPIEIAIAVLVLAVLL Mb0208c|M.bovis_AF2122/97 GDQSGQTANGKVRLYVIGQGALSAAAAANTKHDIANAERWNLPIILMVLV Rv0202c|M.tuberculosis_H37Rv GDQSGQTANGKVRLYVIGQGALSAAAAANTKHDIANAERWNLPIILMVLV MLBr_02617|M.leprae_Br4923 GDQAGRTANGKVRLYVIGQGALSAAVAANSKHDIAEAERWNLPIILIVLL Mflv_0224|M.gilvum_PYR-GCK ITYRSPVLWLVPLLVIGFADRVAAVIGSAVAEALGMSPDGSTSGITSVLV Mvan_0683|M.vanbaalenii_PYR-1 VTYRSPVLWLVPLLVIGFADRVAAVAGAAVAETLGMSPDGSTAGITSVLV MSMEG_0763|M.smegmatis_MC2_155 VTYRSPILWLVPLLVIAFADRVGSVVGTAVASGLGMNPDGSTGGITSVLV TH_3700|M.thermoresistible__bu ------------------------XVGSHIADAFGLMPDGSTSGITSVLV MMAR_1673|M.marinum_M LTYRSPVLWLLPLLVIAFADRVATTVGTAVAALTGLNFDGSTSGITSVLV MUL_1909|M.ulcerans_Agy99 LTYRSSVLWLLPLLVIAFADRVATTVGTAVAALTGLNFDGSTSGITSVLV MAV_3895|M.avium_104 ATYRSPVLWLVPLLVVAFADRVAAAVGTAVASLTGLSFDGATSGITSVLV MAB_0937c|M.abscessus_ATCC_199 LVYRSALTMMLPLVTIGSSLVIAQSVVAAYSQLTGAGVSNQSIVFLSAIL Mb0208c|M.bovis_AF2122/97 AVFGSLAAAAIPLALAVCTVVITMGLVFVLSMHTTMSVFVTST--VSMFG Rv0202c|M.tuberculosis_H37Rv AVFGSLAAAAIPLALAVCTVVITMGLVFVLSMHTTMSVFVTST--VSMFG MLBr_02617|M.leprae_Br4923 AVFGSLAAAAVPLALGVCTVVVTMGLVDLVSMHTIMSVFVTST--VSMFG : : * : Mflv_0224|M.gilvum_PYR-GCK FGAGTNYALLLISRYREELGR-----TDSHNDAIDTAVRRAGPAIIASNA Mvan_0683|M.vanbaalenii_PYR-1 FGAGTNYALLLISRYREELGR-----SESHRDALGTAVRRAGPAIIASNA MSMEG_0763|M.smegmatis_MC2_155 FGAGTNYALLLISRYREELGR-----TENHRDALQASVRAAAPAIIASNA TH_3700|M.thermoresistible__bu FGAGTNYSLLLISRYREELGRGGEQAHPDHHAALRVAVRNAGPAILASNA MMAR_1673|M.marinum_M FGAGTNYALLLISRYRQELPV-----HRDHRDALARAVRMAGPAIAASNA MUL_1909|M.ulcerans_Agy99 FGAGTNYALLLISRYRQELPV-----HRDHRDALARAVRMAGPPIAASNA MAV_3895|M.avium_104 FGAGTNYALLLISRYRQELRR-----HAGHRDALRRAVHRAGPAIVASNA MAB_0937c|M.abscessus_ATCC_199 AGAGTDYAVFLISRYHDYLRS-----GKNYDQAVRAAMMSIGKVITASAT Mb0208c|M.bovis_AF2122/97 IALAVDYSLFILMRYREELRC-----GRRPPDAVDAAMATSGLAVVLSGM Rv0202c|M.tuberculosis_H37Rv IALAVDYSLFILMRYREELRC-----GRRPPDAVDAAMATSGLAVVLSGM MLBr_02617|M.leprae_Br4923 IALAVDYSLFILMRFREELRS-----GRQPQEAVDAAMATSGLAVVLSGM . ..:*::::: *::: * *: :: . : * Mflv_0224|M.gilvum_PYR-GCK TVVLALLTLLFASSPSTRSLGVQAAAGLVVAAVFVLLVLPPALAVFGRKL Mvan_0683|M.vanbaalenii_PYR-1 TVVLALLTLLLASSPSTRSLGVQAASGLVIAAVFVLLVLPPALGVFGRKL MSMEG_0763|M.smegmatis_MC2_155 TVVLALLTLLFATAPSNRSLGVQAASGLVVAAVFVLIVLPPLLALCGKRL TH_3700|M.thermoresistible__bu TVVLALLTLLFGVVPSTRSLGLQAASGLVVAAVFVLLVLPPLLALFGRRL MMAR_1673|M.marinum_M TVVLALLTLVFAATPSTRSLGALAACGLVVAAVSVLVVLPPLLALCGRRL MUL_1909|M.ulcerans_Agy99 TVVLALLTLVFAATPSNRSLGALAACGVVVAAVSVLVVLPPLLALCGRRL MAV_3895|M.avium_104 TVVLALLTLLLAATPSTRSLGALAACGLVIAAVSVLVVLPPLLAVCGRRL MAB_0937c|M.abscessus_ATCC_199 TVGITFLLLSFAKMGVFQTVGVSSAIGIGVAYLSGMTLLPAILVLAGPR- Mb0208c|M.bovis_AF2122/97 TVIASLTGIYLINTPALRSMATGAILAVAVAMLTSATLTPAVLATFARAA Rv0202c|M.tuberculosis_H37Rv TVIASLTGIYLINTPALRSMATGAILAVAVAMLTSATLTPAVLATFARAA MLBr_02617|M.leprae_Br4923 TVIASLTGIYLINTAALKSMATGAILAVAIAMLASITLTPAALATFGRAA ** :: : : :::. : .: :* : : *. * . Mflv_0224|M.gilvum_PYR-GCK FW--PFIPAVGDQPLTDSGVWHRIAAAVARRPARVAIVSIGGLALLCTGI Mvan_0683|M.vanbaalenii_PYR-1 FW--PFIPQVGAKPLTDSGVWHRVAAAVARRPARVAIVSIGGLALLCTGL MSMEG_0763|M.smegmatis_MC2_155 FW--PFIPKVGATALTESGVWHRIADTVARRPARVVVVSVAGLALLCTAL TH_3700|M.thermoresistible__bu FW--PFVPQPGAEPLTDSGLWRRIADWVADRPGPVAAATLAVLAVMCTGL MMAR_1673|M.marinum_M FW--PFIPRAEDTTALDSGFWHAVAQRVARRPAPVALVTVALLIGLATGL MUL_1909|M.ulcerans_Agy99 FW--PFIPRAEDTTALDSGFWHAVAQRVARRPAPVALVTVALLIGLATGL MAV_3895|M.avium_104 FW--PFIP--VDRPATESGAWRRVAEWVAGRPALVAVAAVAVLAALGGGL MAB_0937c|M.abscessus_ATCC_199 -------GWVKPRRELTAQFWRRSGIRIVRRPIPHLVASVLVLALLGSCA Mb0208c|M.bovis_AF2122/97 AKRSALVHWSRRPASTQSWFWSRWVGWVMRRPWITALAASTVLLVMAAPA Rv0202c|M.tuberculosis_H37Rv AKRSALVHWSRRPASTQSWFWSRWVGWVMRRPWITALAASTVLLVMAAPA MLBr_02617|M.leprae_Br4923 VKRSVLMHWSQRSECTQSLFWTRWVGWVMHRPWISASAASTILIIMATPV : * : ** .: * : Mflv_0224|M.gilvum_PYR-GCK LGTPVGLSQTEQFRVEAESVRGFDTLAAHFPSGLTDPTRVIATSDRS--- Mvan_0683|M.vanbaalenii_PYR-1 LGTPVGLSQTEQFRVQAESVSGFETLAAHFPSGLTAPARVIASTDRA--- MSMEG_0763|M.smegmatis_MC2_155 LTTPIGLTQTEQFRVQAESVSGFETVSAHFPSGLTDPTRVIASTDKA--- TH_3700|M.thermoresistible__bu LGTPIGLSQTEQFRVQAESVTGYETLAAHFPRGITDPTQVLASTERA--- MMAR_1673|M.marinum_M LGTRIGLSQTEQFRVKADSVSGYDVVAQHFPAGLVNPTLVVAPSAQA--- MUL_1909|M.ulcerans_Agy99 LGTRIGLSQTEQFRVKADSVSGYDVVAQHFPAGLVNPTLVVAPSAQA--- MAV_3895|M.avium_104 WGTRIGLSQTEQFRVRADSVAGYHVLAQHFPAGLANPTLVVADTGHA--- MAB_0937c|M.abscessus_ATCC_199 LLARYNYDDRKAVSPSAPSSVGYAALERHFPLSQSIPEYILIQSPRD--- Mb0208c|M.bovis_AF2122/97 TLMVLGNSLLRQFDSSHEIRTGAAAAAQALGPGALGPVQVLVRFDAG--- Rv0202c|M.tuberculosis_H37Rv TLMVLGNSLLRQFDSSHEIRTGAAAAAQALGPGALGPVQVLVRFDAG--- MLBr_02617|M.leprae_Br4923 TSMMLGNSLLRQFNSSHEIRAGVAAAAQALGPGALGPVQVLITFPDDPNT . . . * . : . * :: Mflv_0224|M.gilvum_PYR-GCK -AEVQRAITATPGVVSAFPAGAE---ADGRS------------------- Mvan_0683|M.vanbaalenii_PYR-1 -AEVQRAITATPGVVSAIPAGSG---PGGVS------------------- MSMEG_0763|M.smegmatis_MC2_155 -AAVQRAITDTEGVVSASPAGES---PTGLT------------------- TH_3700|M.thermoresistible__bu -NEVELAITETPGVVSAAESGRS---GTGLT------------------- MMAR_1673|M.marinum_M -TQVRQAIGATPGVVSVTESGRSGKFGAGLT------------------- MUL_1909|M.ulcerans_Agy99 -TQVRQAIGATPGVVSVTESGRSGKFGAGLT------------------- MAV_3895|M.avium_104 -AAVHQAMAATPGVVSATESGRS---ASGLT------------------- MAB_0937c|M.abscessus_ATCC_199 -LRTPQALADLEQMASRIAQLPDVGLVSGVTRPLGEVPPEFRATYQAGLV Mb0208c|M.bovis_AF2122/97 GASAPEHSQTIAAIRHRIAQAPNVVSVAPPRFAD---------------- Rv0202c|M.tuberculosis_H37Rv GASAPEHSQTIAAIRHRIAQAPNVVSVAPPRFAD---------------- MLBr_02617|M.leprae_Br4923 QASSPKHRQTIGAIRNRMLQAKNVMSVAPPQFAD---------------- : Mflv_0224|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0683|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0763|M.smegmatis_MC2_155 -------------------------------------------------- TH_3700|M.thermoresistible__bu -------------------------------------------------- MMAR_1673|M.marinum_M -------------------------------------------------- MUL_1909|M.ulcerans_Agy99 -------------------------------------------------- MAV_3895|M.avium_104 -------------------------------------------------- MAB_0937c|M.abscessus_ATCC_199 GTRLADGSNQINQRSSDLNRLTSGANTLAGSLTDLRNQLNKITPGLQSLL Mb0208c|M.bovis_AF2122/97 -------------------------------------------------- Rv0202c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02617|M.leprae_Br4923 -------------------------------------------------- Mflv_0224|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0683|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0763|M.smegmatis_MC2_155 -------------------------------------------------- TH_3700|M.thermoresistible__bu -------------------------------------------------- MMAR_1673|M.marinum_M -------------------------------------------------- MUL_1909|M.ulcerans_Agy99 -------------------------------------------------- MAV_3895|M.avium_104 -------------------------------------------------- MAB_0937c|M.abscessus_ATCC_199 EASNSLKTKSGGDELVRNVDNAAKLVDEINALANDMGWNFSAAKDMFGWI Mb0208c|M.bovis_AF2122/97 -------------------------------------------------- Rv0202c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02617|M.leprae_Br4923 -------------------------------------------------- Mflv_0224|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0683|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0763|M.smegmatis_MC2_155 -------------------------------------------------- TH_3700|M.thermoresistible__bu -------------------------------------------------- MMAR_1673|M.marinum_M -------------------------------------------------- MUL_1909|M.ulcerans_Agy99 -------------------------------------------------- MAV_3895|M.avium_104 -------------------------------------------------- MAB_0937c|M.abscessus_ATCC_199 NPVLAALQGNPICDADTSCSNTRGQFERLVGERNSGRLDEIERLAHQLGN Mb0208c|M.bovis_AF2122/97 -------------------------------------------------- Rv0202c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02617|M.leprae_Br4923 -------------------------------------------------- Mflv_0224|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0683|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0763|M.smegmatis_MC2_155 -------------------------------------------------- TH_3700|M.thermoresistible__bu -------------------------------------------------- MMAR_1673|M.marinum_M -------------------------------------------------- MUL_1909|M.ulcerans_Agy99 -------------------------------------------------- MAV_3895|M.avium_104 -------------------------------------------------- MAB_0937c|M.abscessus_ATCC_199 SPGNKATLSTTVTKLNASLLSVVNGLHAMGLDKPGGPQAGLNQLRQGADR Mb0208c|M.bovis_AF2122/97 -------------------------------------------------- Rv0202c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02617|M.leprae_Br4923 -------------------------------------------------- Mflv_0224|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0683|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0763|M.smegmatis_MC2_155 -------------------------------------------------- TH_3700|M.thermoresistible__bu -------------------------------------------------- MMAR_1673|M.marinum_M -------------------------------------------------- MUL_1909|M.ulcerans_Agy99 -------------------------------------------------- MAV_3895|M.avium_104 -------------------------------------------------- MAB_0937c|M.abscessus_ATCC_199 LAGGSQQVAGGVDQLVGQIKVIVNGLNQASNFLLTMKTNAADPSQAGFNI Mb0208c|M.bovis_AF2122/97 -------------------------------------------------- Rv0202c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_02617|M.leprae_Br4923 -------------------------------------------------- Mflv_0224|M.gilvum_PYR-GCK -------------------------QWSVVLDAEPASDEAFDTIDALRES Mvan_0683|M.vanbaalenii_PYR-1 -------------------------QWSVVLEAAPASDAAFEAVDALRDS MSMEG_0763|M.smegmatis_MC2_155 -------------------------QWSVVLGADPASDEAFETIDALRGS TH_3700|M.thermoresistible__bu -------------------------QWSVVLDAEPASAEAFETVDALRDS MMAR_1673|M.marinum_M -------------------------KWSVVIDAPPSSERAFTTIAALRHS MUL_1909|M.ulcerans_Agy99 -------------------------KWSVVIDAPPSSERAFTTIAALRHS MAV_3895|M.avium_104 -------------------------QWSVVIDAPPSSVRAFDIVAALRDS MAB_0937c|M.abscessus_ATCC_199 PAEVLNNPDFQRAAKAFISPDGHSVRYLVQTKLNPFSPEAMDQVNQISDV Mb0208c|M.bovis_AF2122/97 --------------------DNGSALLSAVLSVDPEDLGARDTITWMRTQ Rv0202c|M.tuberculosis_H37Rv --------------------DNGSALLSAVLSVDPEDLGARDTITWMRTQ MLBr_02617|M.leprae_Br4923 --------------------NNCSALLGAVLSVDPEDLGARETVDWMRTE . * . * : : Mflv_0224|M.gilvum_PYR-GCK VH-------RADPDALVGGSDATARDAAAAAGHDRAVVIPAILVVVLIVL Mvan_0683|M.vanbaalenii_PYR-1 VH-------RVDPDALVGGSDATARDAASAAAHDRAVVIPAILVVVLLVL MSMEG_0763|M.smegmatis_MC2_155 VQ-------HADADAVVGGSDAQARDAAAAAQRDRAVVIPAILVVVLAVL TH_3700|M.thermoresistible__bu VR-------KADQSALVGGSDAQARDASAASTRDRLVLIPAILVVVLAVL MMAR_1673|M.marinum_M AS-------QASPSALVGGPDAQALDVRDAAEHDRALLIPAILAVILVVL MUL_1909|M.ulcerans_Agy99 AS-------QASPSALVGGPDAQALDVRDAAEHDRALLIPAILAVILVVL MAV_3895|M.avium_104 TR-------AADSGALVGGADAAALDVRDAATHDRVLLIPAILAVILIVL MAB_0937c|M.abscessus_ATCC_199 AKGAQPNTTLADATISMGGFPTALRDTRDYYQHDIQFIIAATLIVVLLTL Mb0208c|M.bovis_AF2122/97 LP-----RVAGAAQVDVGGPTALIKDFDDRVSATQPLVLVFVAVIAFLML Rv0202c|M.tuberculosis_H37Rv LP-----RVAGAAQVDVGGPTALIKDFDDRVSATQPLVLVFVAVIAFLML MLBr_02617|M.leprae_Br4923 LP-----KVPGAAHVNVGGPTALINDFDDRVAKTEPLMLVFVALIAFVML :** : * .:: : : * Mflv_0224|M.gilvum_PYR-GCK YVLLRSALAPLVLVGVTVLSSVAALG-------LGGWASVHLFGFPALDN Mvan_0683|M.vanbaalenii_PYR-1 YLLLRSALAPLVLVGVTVLSALAALG-------LGGWASVHVFGFPALDY MSMEG_0763|M.smegmatis_MC2_155 YILLRSAFAPLLLVGVTVLSSLAALG-------LGGWASVHIFGFPALDN TH_3700|M.thermoresistible__bu YVLLRAALAPLVLVAVSLLSSLAALG-------LGGWISVHVFGFPALDF MMAR_1673|M.marinum_M YALLRSALAPLILLAATILGALAALG-------LGGWASIHVFGFPALDN MUL_1909|M.ulcerans_Agy99 YALLRSALAPLILLAATILGALAALG-------LGGWASIHVFGFPALDN MAV_3895|M.avium_104 AVLLRSVMAPPVLLVATMLGALGALG-------LGGWVSLHLFGFPALDY MAB_0937c|M.abscessus_ATCC_199 MVLLRAIVAPLYLVGSVVLSYFAAIG-------IGVLTFQYLLG-EQLHW Mb0208c|M.bovis_AF2122/97 LISIRSVFLAFKGVLMTLLSVAAAYGSLVMVFQWGWARGLGFPALHSIDS Rv0202c|M.tuberculosis_H37Rv LISIRSVFLAFKGVLMTLLSVAAAYGSLVMVFQWGWARGLGFPALHSIDS MLBr_02617|M.leprae_Br4923 LISIRSVFLAFKGVLMTLLSVAAAYGSLVMVFQWGWLENLGFTHINSIDS :*: . . : :*. .* * * . :. Mflv_0224|M.gilvum_PYR-GCK TAPLFAFLFLVALGVDYTIFLVTRAREETPGHG-TRDGIVRAVSATGAVI Mvan_0683|M.vanbaalenii_PYR-1 TAPLFAFLFLVALGVDYTIFLVTRAREETPEHG-TRDGIVRAVSATGAVI MSMEG_0763|M.smegmatis_MC2_155 GTPLFAFLFLVALGVDYTIFLVTRAREETPQYG-NREGIVRAVSATGAVI TH_3700|M.thermoresistible__bu ATPLFALLFLVALGVDYTIFLVTRAREETVGHG-TRGGIVRAVSATGAVI MMAR_1673|M.marinum_M STPLFAFLFLAALGVDYTIFLVTRAREESARNG-ARAGMVRAVSATGGVI MUL_1909|M.ulcerans_Agy99 STPLFAFLFLAALGVDYTIFLVTRAREESARNG-ARAGMVRAVSATGGVI MAV_3895|M.avium_104 TTPLFAFLFLAALGVDYTIFLVARAREEAARHG-TRQGMVEAVAATGGVI MAB_0937c|M.abscessus_ATCC_199 TVPPLAFVVLVAVGADYNMLFVSRMRDESASS--VRYGIIRALNSTGGVI Mb0208c|M.bovis_AF2122/97 TVPPLVLAMTFGLSMDYEIFLLTRIRERFLQTGQTRDAVAYGVRTSARTI Rv0202c|M.tuberculosis_H37Rv TVPPLVLAMTFGLSMDYEIFLLTRIRERFLQTGQTRDAVAYGVRTSARTI MLBr_02617|M.leprae_Br4923 TVPPLVLAMTFGLSMDYEIFLLTRIRERFLQTGHTRDAVAYGVSTSARTI .* :.: . .:. ** :::::* *:. * .: .: ::. .* Mflv_0224|M.gilvum_PYR-GCK SSAGIVLAAVFCVLGVLPLIVLTQVGIIVGLGILLDTFLVRTVIIPALFT Mvan_0683|M.vanbaalenii_PYR-1 TSAGIVLAAVFCVLGVLPLIVLTQVGIIVGLGILLDTFVVRTVIIPALFT MSMEG_0763|M.smegmatis_MC2_155 TSAGVVLAAVFCVLGVLPLIVLTQLGIIVGLGILLDTFLVRTVIIPALFT TH_3700|M.thermoresistible__bu TSAGIVLAAVFCVLGVLPLIVLTQLGIIVGLGILLDTFVVRTVVVPALFT MMAR_1673|M.marinum_M TSAGIVLAAVFCVLAVLPLIVLTQLGIIVGLGILLDTFVVRTLVIPALFT MUL_1909|M.ulcerans_Agy99 TSAGIVLAAVFCVLAVLPLIVLTQLGIIVGLGILLDTFVVRTLVIPALFT MAV_3895|M.avium_104 TSAGIVLAAVFCVLAVLPLMVLTQLGIIVGLGILLDTFVVRTLVIPALFT MAB_0937c|M.abscessus_ATCC_199 TAAGLIFAASVGGLLFSSIGIVVQGGFVIGVGILLDTFVVRTITVPAIAA Mb0208c|M.bovis_AF2122/97 TSAALIMIAVFCGFAFAGMPLVAEIGVACAVAIAVDATVVRLVLVPALMA Rv0202c|M.tuberculosis_H37Rv TSAALIMIAVFCGFAFAGMPLVAEIGVACAVAIAVDATVVRLVLVPALMA MLBr_02617|M.leprae_Br4923 TSAALIMIAVFVGFAFAGMPLVAEIGVACAVAIAVDVTAVRLVLVPTLMA ::*.::: * . : . : ::.: *. .:.* :*. ** : :*:: : Mflv_0224|M.gilvum_PYR-GCK LIGPKIWWPALRQETRSDA------------------------------- Mvan_0683|M.vanbaalenii_PYR-1 LIGPRIWWPALREDGPSRGR------------------------------ MSMEG_0763|M.smegmatis_MC2_155 WIGPKIWWPGLRAEP----------------------------------- TH_3700|M.thermoresistible__bu LIGPRMWWPALRAAE----------------------------------- MMAR_1673|M.marinum_M LIGDRIWWPSDPKTTAHQPDLAYSHADGGSE------------------- MUL_1909|M.ulcerans_Agy99 LIGDRIWWPSDPKTTAHQPDLAYSHADGGSE------------------- MAV_3895|M.avium_104 LVGDRIWWPNNP--SRHERSTP---------------------------- MAB_0937c|M.abscessus_ATCC_199 LVGKANWWPSQVNARQTSSAKPSAAAPAG--------------------- Mb0208c|M.bovis_AF2122/97 MFDRWNWWLPRWLAHILPSVDFDRPLPKVDLGDVVVIPDDFAAAIPPSAD Rv0202c|M.tuberculosis_H37Rv MFDRWNWWLPRWLAHILPSVDFDRPLPKVDLGDVVVIPDDFAAAIPPSAD MLBr_02617|M.leprae_Br4923 MFAQWNWWLPRWLSRALPAVDFDKPFPPVDLNEIVVLPADISATKVPCGD . ** Mflv_0224|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0683|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0763|M.smegmatis_MC2_155 -------------------------------------------------- TH_3700|M.thermoresistible__bu -------------------------------------------------- MMAR_1673|M.marinum_M -------------------------------------------------- MUL_1909|M.ulcerans_Agy99 -------------------------------------------------- MAV_3895|M.avium_104 -------------------------------------------------- MAB_0937c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0208c|M.bovis_AF2122/97 VRMVLKSAAKLKRLAPDAICVTDPLAFTGCGCDGKALDQVQ--------- Rv0202c|M.tuberculosis_H37Rv VRMVLKSAAKLKRLAPDAICVTDPLAFTGCGCDGKALDQVQ--------- MLBr_02617|M.leprae_Br4923 LRMVLKLAAKLKNLAPDAICVADPLAFTGCGRNNKRSDRVLPGAATQESE Mflv_0224|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0683|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0763|M.smegmatis_MC2_155 -------------------------------------------------- TH_3700|M.thermoresistible__bu -------------------------------------------------- MMAR_1673|M.marinum_M -------------------------------------------------- MUL_1909|M.ulcerans_Agy99 -------------------------------------------------- MAV_3895|M.avium_104 -------------------------------------------------- MAB_0937c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0208c|M.bovis_AF2122/97 --------------------------------------LAYRNGIARAIS Rv0202c|M.tuberculosis_H37Rv --------------------------------------LAYRNGIARAIS MLBr_02617|M.leprae_Br4923 EDPAMGKASDSTAALTAAQVGPVTRTNGHWTARNLVIGLTHRNSITRVMP Mflv_0224|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0683|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0763|M.smegmatis_MC2_155 -------------------------------------------------- TH_3700|M.thermoresistible__bu -------------------------------------------------- MMAR_1673|M.marinum_M -------------------------------------------------- MUL_1909|M.ulcerans_Agy99 -------------------------------------------------- MAV_3895|M.avium_104 -------------------------------------------------- MAB_0937c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0208c|M.bovis_AF2122/97 WGQRPVHPVTVWRKRLAVALDALQTTTWECGGVQTHRAGPGYRRRSPVET Rv0202c|M.tuberculosis_H37Rv WGQRPVHPVTVWRKRLAVALDALQTTTWECGGVQTHRAGPGYRRRSPVET MLBr_02617|M.leprae_Br4923 WSDRPVHPFTLWRSRFSVAIDALEAHIAVQADAPDQ---PNYQRCSPVET Mflv_0224|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0683|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0763|M.smegmatis_MC2_155 -------------------------------------------------- TH_3700|M.thermoresistible__bu -------------------------------------------------- MMAR_1673|M.marinum_M -------------------------------------------------- MUL_1909|M.ulcerans_Agy99 -------------------------------------------------- MAV_3895|M.avium_104 -------------------------------------------------- MAB_0937c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0208c|M.bovis_AF2122/97 TNVALPTGDRLQIPTGAETLRFKGYLIMSRNSSHDYADFADLVDTMAPET Rv0202c|M.tuberculosis_H37Rv TNVALPTGDRLQIPTGAETLRFKGYLIMSRNSSHDYADFADLVDTMAPET MLBr_02617|M.leprae_Br4923 AHVQLPTGDRLLIPTGAETLRLVSYLIMCRNSIRDYAELADMVDAIEPET Mflv_0224|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0683|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0763|M.smegmatis_MC2_155 -------------------------------------------------- TH_3700|M.thermoresistible__bu -------------------------------------------------- MMAR_1673|M.marinum_M -------------------------------------------------- MUL_1909|M.ulcerans_Agy99 -------------------------------------------------- MAV_3895|M.avium_104 -------------------------------------------------- MAB_0937c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0208c|M.bovis_AF2122/97 AAAVLAGMDRYYSCQAPGRQWMATQLVGRLADPQPSDLGD-QSPGADAQA Rv0202c|M.tuberculosis_H37Rv AAAVLAGMDRYYSCQAPGRQWMATQLVGRLADPQPSDLGD-QSPGADAQA MLBr_02617|M.leprae_Br4923 AAVVLTELDRYYSCQLPMRQWMATQLVRRLSDPHPVDLTEDQWSDPDNKA Mflv_0224|M.gilvum_PYR-GCK --------------------- Mvan_0683|M.vanbaalenii_PYR-1 --------------------- MSMEG_0763|M.smegmatis_MC2_155 --------------------- TH_3700|M.thermoresistible__bu --------------------- MMAR_1673|M.marinum_M --------------------- MUL_1909|M.ulcerans_Agy99 --------------------- MAV_3895|M.avium_104 --------------------- MAB_0937c|M.abscessus_ATCC_199 --------------------- Mb0208c|M.bovis_AF2122/97 KWEEVRRRCLSVAVAMLEEAR Rv0202c|M.tuberculosis_H37Rv KWEEVRRRCLSVAVAMLEEAR MLBr_02617|M.leprae_Br4923 EWQDVRQRCLSVAVAMLEEAR