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VWDRLAAALAAKRSWLISVGVVALATVFMVLVGGNSAAGQAPQSVPADVESAKVESELGRFPGGDRAPLI LVVTRSDGTTLDAADRRAAQQAAQRMQASAHPGANPRPAAPLISADTKAAISVVPISANLSGLALNDAVK ALREAAHEGLPADLDAHVTGGPAFGADIANAFTNANITLLAVTASVVALLLILTYRSSVLWLLPLLVIAF ADRVATTVGTAVAALTGLNFDGSTSGITSVLVFGAGTNYALLLISRYRQELPVHRDHRDALARAVRMAGP PIAASNATVVLALLTLVFAATPSNRSLGALAACGVVVAAVSVLVVLPPLLALCGRRLFWPFIPRAEDTTA LDSGFWHAVAQRVARRPAPVALVTVALLIGLATGLLGTRIGLSQTEQFRVKADSVSGYDVVAQHFPAGLV NPTLVVAPSAQATQVRQAIGATPGVVSVTESGRSGKFGAGLTKWSVVIDAPPSSERAFTTIAALRHSASQ ASPSALVGGPDAQALDVRDAAEHDRALLIPAILAVILVVLYALLRSALAPLILLAATILGALAALGLGGW ASIHVFGFPALDNSTPLFAFLFLAALGVDYTIFLVTRAREESARNGARAGMVRAVSATGGVITSAGIVLA AVFCVLAVLPLIVLTQLGIIVGLGILLDTFVVRTLVIPALFTLIGDRIWWPSDPKTTAHQPDLAYSHADG GSE*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_1909 | - | - | 100% (704) | transmembrane transport protein |
M. ulcerans Agy99 | MUL_1092 | mmpL11 | 4e-39 | 25.46% (707) | transmembrane transport protein MmpL11 |
M. ulcerans Agy99 | MUL_0989 | mmpL13 | 1e-34 | 24.31% (765) | transmembrane transport protein MmpL13 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0208c | mmpL11 | 3e-40 | 25.42% (716) | transmembrane transport protein MmpL11 |
M. gilvum PYR-GCK | Mflv_0224 | - | 0.0 | 63.46% (676) | MMPL domain-containing protein |
M. tuberculosis H37Rv | Rv0202c | mmpL11 | 3e-40 | 25.42% (716) | transmembrane transport protein MmpL11 |
M. leprae Br4923 | MLBr_02617 | - | 3e-34 | 24.62% (719) | hypothetical protein MLBr_02617 |
M. abscessus ATCC 19977 | MAB_4529 | - | 4e-46 | 26.88% (703) | putative membrane protein, MmpL |
M. marinum M | MMAR_1673 | - | 0.0 | 99.15% (704) | transmembrane transport protein |
M. avium 104 | MAV_3895 | - | 0.0 | 73.47% (686) | MmpL family protein |
M. smegmatis MC2 155 | MSMEG_0763 | - | 0.0 | 65.27% (668) | antibiotic transporter |
M. thermoresistible (build 8) | TH_3700 | - | 1e-172 | 68.30% (470) | PUTATIVE MMPL domain protein |
M. vanbaalenii PYR-1 | Mvan_0683 | - | 0.0 | 63.50% (674) | MMPL domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment MUL_1909|M.ulcerans_Agy99 MVWDRLAAALAAKRSWLISVGVVALATVFMVLVGGNSAAGQAPQSVPADV MMAR_1673|M.marinum_M MVWDRLAAALAAKRSWLISVGVVALATVFMVLVGGNSAAGQAPQSVPADA MAV_3895|M.avium_104 MVWERVAAAVTGPRSWLLAAVAVLAGVGVMALVGPNTAAGQAPQSLPQHS Mflv_0224|M.gilvum_PYR-GCK ---------MSRRFSWVIALLVVLVSGALMGLLGGGDSSSQSPVAVPADS Mvan_0683|M.vanbaalenii_PYR-1 ---------MSRRYSWVVALLVVLLSGALMGLLGGGDSGSQSPLIVPPDA MSMEG_0763|M.smegmatis_MC2_155 ---------MS-----WLAVLVVIISGGLMGVLSGGDSASQSPVAVPSDA TH_3700|M.thermoresistible__bu -------------------------------------------------- Mb0208c|M.bovis_AF2122/97 --MMRLSRNLRRCRWLVFTGWLLALVPAVYLAMTQSGNLTGGGFEVAGSQ Rv0202c|M.tuberculosis_H37Rv --MMRLSRNLRRCRWLVFTGWLLALVPAVYLAMTQSGNLTGGGFEVAGSQ MLBr_02617|M.leprae_Br4923 ---MRLSSYLRRFRWLVFTGWLLALVPAIYLAMTQSGKLTGGGFEVAGSQ MAB_4529|M.abscessus_ATCC_1997 --MMRTSDYLRRYRWLTVAVWLILIVAAVGLVAGRGEKLTGGGFEVAGSQ MUL_1909|M.ulcerans_Agy99 ESAKVESELGRFPGGDRAPLILVVTRSDGTTLDAADRRAAQQAAQRMQAS MMAR_1673|M.marinum_M ESAKVESELGRFPGGDRAPLILVVTRSDGTTLDAADRRAAQQAAQRMQAA MAV_3895|M.avium_104 PSARITALAGQFPGGDRTPLIVVVSRADGAVLGPADLGAARAARDRAQAA Mflv_0224|M.gilvum_PYR-GCK ESARADAARAALPGGDQVPAILVVTRTDSAPLGPADLAAVDGARDRMLAA Mvan_0683|M.vanbaalenii_PYR-1 ESARADAARAALPDGDQVPAILVVTRADAAPLTPADVAAANSARDRMLTV MSMEG_0763|M.smegmatis_MC2_155 ESARADALRADFPGGDQAPAILVVTRADGAELGPDDIDAAAEARHRMSDA TH_3700|M.thermoresistible__bu -------------------------------------------------- Mb0208c|M.bovis_AF2122/97 SLLVHDQLDAHYPDRGAPALALVAAPRPDASYQDIDNAVALLRQIASELP Rv0202c|M.tuberculosis_H37Rv SLLVHDQLDAHYPDRGAPALALVAAPRPDASYQDIDNAVALLRQIASELP MLBr_02617|M.leprae_Br4923 SLLVHDQLQEQYPDQGAVSLALVAAPRSDASYQDMNDAVALLRRIVSEFP MAB_4529|M.abscessus_ATCC_1997 SLKVHDAMETGFREQGASPLALVAAPRPDATVSDMAAAVDYLKQVAAQIP MUL_1909|M.ulcerans_Agy99 AHPGANPRPAAPLIS-ADTKAAISVVPISANLSGLALNDAVKALREAAHE MMAR_1673|M.marinum_M AHPGANPRPAAPLIS-ADTKAAISVVPISANLSGLALNDAVKALREAAHE MAV_3895|M.avium_104 AQPGAAP--AQPLTPSQDGKAALGVVPLSTTLSGLALNDAVSALRTAAAT Mflv_0224|M.gilvum_PYR-GCK AQS---GPAGPPVQVSDDGQAAVATVPMSSDLSGFDLTDTVTELRGAATD Mvan_0683|M.vanbaalenii_PYR-1 AGN---AAGGPPTQVSEDGQAAVATVPLSADLSGFALTDKVKEVRTAAAD MSMEG_0763|M.smegmatis_MC2_155 P--------GPPMVVSDDGKAAISTVPLDATLSGFALTDEVKELRANAAE TH_3700|M.thermoresistible__bu -------------------------------------------------- Mb0208c|M.bovis_AF2122/97 GVTEAPNPTQRPPQPDRPYVVSLRLDARNAGTSDVAKKLRDRIGVKGDQS Rv0202c|M.tuberculosis_H37Rv GVTEAPNPTQRPPQPDRPYVVSLRLDARNAGTSDVAKKLRDRIGVKGDQS MLBr_02617|M.leprae_Br4923 GVSEVPNPTQLPPRPDRPYGVSLRLDDRNSVTSDVAKQLRTKVGIKGDQA MAB_4529|M.abscessus_ATCC_1997 QVSVEPIPPQLTPQPDRPFVVTLRIGFDNTGATDIAKSLRKKIGVHGGQP MUL_1909|M.ulcerans_Agy99 G--LPADLDAHVTGGPAFGADIANAFTNANITLLAVTASVVALLLILTYR MMAR_1673|M.marinum_M G--LPADLDAHVTGGPAFGADIANAFTNANITLLAVTASVVALLLILTYR MAV_3895|M.avium_104 G--LAADLQVHVTGGPAFGADIAGAFTHANVTLLAVTASVVALLLIATYR Mflv_0224|M.gilvum_PYR-GCK G--LPEGLQAQVTGGPAFGADIANSFSGANFTLLAVTAAVVALLLIITYR Mvan_0683|M.vanbaalenii_PYR-1 G--LPGDLRAQVTGGPAFGADIADSFSGANVTLLAVTAAVVALLLIVTYR MSMEG_0763|M.smegmatis_MC2_155 G--LPGDLRAEVTGGPAFGADIANSFAGANVTLLAVTAIVVALLLIVTYR TH_3700|M.thermoresistible__bu -------------------------------------------------- Mb0208c|M.bovis_AF2122/97 GQTANGKVRLYVIGQGALSAAAAANTKHDIANAERWNLPIILMVLVAVFG Rv0202c|M.tuberculosis_H37Rv GQTANGKVRLYVIGQGALSAAAAANTKHDIANAERWNLPIILMVLVAVFG MLBr_02617|M.leprae_Br4923 GRTANGKVRLYVIGQGALSAAVAANSKHDIAEAERWNLPIILIVLLAVFG MAB_4529|M.abscessus_ATCC_1997 GQIAGGRVSLYVIGQGALGAAMTEQIAGDIKKAEKWNIPVILIVLIAAFG MUL_1909|M.ulcerans_Agy99 SSVLWLLPLLVIAFADRVATTVGTAVAALTGLNFDGSTSGITSVLVFGAG MMAR_1673|M.marinum_M SPVLWLLPLLVIAFADRVATTVGTAVAALTGLNFDGSTSGITSVLVFGAG MAV_3895|M.avium_104 SPVLWLVPLLVVAFADRVAAAVGTAVASLTGLSFDGATSGITSVLVFGAG Mflv_0224|M.gilvum_PYR-GCK SPVLWLVPLLVIGFADRVAAVIGSAVAEALGMSPDGSTSGITSVLVFGAG Mvan_0683|M.vanbaalenii_PYR-1 SPVLWLVPLLVIGFADRVAAVAGAAVAETLGMSPDGSTAGITSVLVFGAG MSMEG_0763|M.smegmatis_MC2_155 SPILWLVPLLVIAFADRVGSVVGTAVASGLGMNPDGSTGGITSVLVFGAG TH_3700|M.thermoresistible__bu --------------------XVGSHIADAFGLMPDGSTSGITSVLVFGAG Mb0208c|M.bovis_AF2122/97 SLAAAAIPLALAVCTVVITMGLVFVLSMHTTMSVFVTST--VSMFGIALA Rv0202c|M.tuberculosis_H37Rv SLAAAAIPLALAVCTVVITMGLVFVLSMHTTMSVFVTST--VSMFGIALA MLBr_02617|M.leprae_Br4923 SLAAAAVPLALGVCTVVVTMGLVDLVSMHTIMSVFVTST--VSMFGIALA MAB_4529|M.abscessus_ATCC_1997 SLAAASLPLLLGVCTVALSVAIVLALSNITTISVFALPT--VTMIGLAVA :: : . .::: :. . MUL_1909|M.ulcerans_Agy99 TNYALLLISRYRQELPV-----HRDHRDALARAVRMAGPPIAASNATVVL MMAR_1673|M.marinum_M TNYALLLISRYRQELPV-----HRDHRDALARAVRMAGPAIAASNATVVL MAV_3895|M.avium_104 TNYALLLISRYRQELRR-----HAGHRDALRRAVHRAGPAIVASNATVVL Mflv_0224|M.gilvum_PYR-GCK TNYALLLISRYREELGR-----TDSHNDAIDTAVRRAGPAIIASNATVVL Mvan_0683|M.vanbaalenii_PYR-1 TNYALLLISRYREELGR-----SESHRDALGTAVRRAGPAIIASNATVVL MSMEG_0763|M.smegmatis_MC2_155 TNYALLLISRYREELGR-----TENHRDALQASVRAAAPAIIASNATVVL TH_3700|M.thermoresistible__bu TNYSLLLISRYREELGRGGEQAHPDHHAALRVAVRNAGPAILASNATVVL Mb0208c|M.bovis_AF2122/97 VDYSLFILMRYREELRC-----GRRPPDAVDAAMATSGLAVVLSGMTVIA Rv0202c|M.tuberculosis_H37Rv VDYSLFILMRYREELRC-----GRRPPDAVDAAMATSGLAVVLSGMTVIA MLBr_02617|M.leprae_Br4923 VDYSLFILMRFREELRS-----GRQPQEAVDAAMATSGLAVVLSGMTVIA MAB_4529|M.abscessus_ATCC_1997 VDYSLFILMRYREELNS-----GKNRQEAIAGAMATSGLTVTFSGLTVIA .:*:*::: *:*:** *: :: :. .: *. **: MUL_1909|M.ulcerans_Agy99 ALLTLVFAATPSNRSLGALAACGVVVAAVSVLVVLPPLLALCGRRLFWP- MMAR_1673|M.marinum_M ALLTLVFAATPSTRSLGALAACGLVVAAVSVLVVLPPLLALCGRRLFWP- MAV_3895|M.avium_104 ALLTLLLAATPSTRSLGALAACGLVIAAVSVLVVLPPLLAVCGRRLFWP- Mflv_0224|M.gilvum_PYR-GCK ALLTLLFASSPSTRSLGVQAAAGLVVAAVFVLLVLPPALAVFGRKLFWP- Mvan_0683|M.vanbaalenii_PYR-1 ALLTLLLASSPSTRSLGVQAASGLVIAAVFVLLVLPPALGVFGRKLFWP- MSMEG_0763|M.smegmatis_MC2_155 ALLTLLFATAPSNRSLGVQAASGLVVAAVFVLIVLPPLLALCGKRLFWP- TH_3700|M.thermoresistible__bu ALLTLLFGVVPSTRSLGLQAASGLVVAAVFVLLVLPPLLALFGRRLFWP- Mb0208c|M.bovis_AF2122/97 SLTGIYLINTPALRSMATGAILAVAVAMLTSATLTPAVLATFARAAAKRS Rv0202c|M.tuberculosis_H37Rv SLTGIYLINTPALRSMATGAILAVAVAMLTSATLTPAVLATFARAAAKRS MLBr_02617|M.leprae_Br4923 SLTGIYLINTAALKSMATGAILAVAIAMLASITLTPAALATFGRAAVKRS MAB_4529|M.abscessus_ATCC_1997 ALAGIYLIGTPALASMASGAIIVVAIAVLTSTTLMPALLAIFGKAAANQS :* : : .: *:. * :.:* : : *. *. .: MUL_1909|M.ulcerans_Agy99 -FIPRAEDTTALDSGFWHAVAQRVARRPAPVALVTVALLIGLATGLLGTR MMAR_1673|M.marinum_M -FIPRAEDTTALDSGFWHAVAQRVARRPAPVALVTVALLIGLATGLLGTR MAV_3895|M.avium_104 -FIP--VDRPATESGAWRRVAEWVAGRPALVAVAAVAVLAALGGGLWGTR Mflv_0224|M.gilvum_PYR-GCK -FIPAVGDQPLTDSGVWHRIAAAVARRPARVAIVSIGGLALLCTGILGTP Mvan_0683|M.vanbaalenii_PYR-1 -FIPQVGAKPLTDSGVWHRVAAAVARRPARVAIVSIGGLALLCTGLLGTP MSMEG_0763|M.smegmatis_MC2_155 -FIPKVGATALTESGVWHRIADTVARRPARVVVVSVAGLALLCTALLTTP TH_3700|M.thermoresistible__bu -FVPQPGAEPLTDSGLWRRIADWVADRPGPVAAATLAVLAVMCTGLLGTP Mb0208c|M.bovis_AF2122/97 ALVHWSRRPASTQSWFWSRWVGWVMRRPWITALAASTVLLVMAAPATLMV Rv0202c|M.tuberculosis_H37Rv ALVHWSRRPASTQSWFWSRWVGWVMRRPWITALAASTVLLVMAAPATLMV MLBr_02617|M.leprae_Br4923 VLMHWSQRSECTQSLFWTRWVGWVMHRPWISASAASTILIIMATPVTSMM MAB_4529|M.abscessus_ATCC_1997 RFLRVSPLRKHSIP-FWRKWTQQVMRRPWLSALGASIFLLALAAPSLQMH :: . * . * ** . : * : MUL_1909|M.ulcerans_Agy99 IGLSQTEQFRVKADSVSGYDVVAQHFPAGLVNPTLVVAPSAQA------- MMAR_1673|M.marinum_M IGLSQTEQFRVKADSVSGYDVVAQHFPAGLVNPTLVVAPSAQA------- MAV_3895|M.avium_104 IGLSQTEQFRVRADSVAGYHVLAQHFPAGLANPTLVVADTGHA------- Mflv_0224|M.gilvum_PYR-GCK VGLSQTEQFRVEAESVRGFDTLAAHFPSGLTDPTRVIATSDRS------- Mvan_0683|M.vanbaalenii_PYR-1 VGLSQTEQFRVQAESVSGFETLAAHFPSGLTAPARVIASTDRA------- MSMEG_0763|M.smegmatis_MC2_155 IGLTQTEQFRVQAESVSGFETVSAHFPSGLTDPTRVIASTDKA------- TH_3700|M.thermoresistible__bu IGLSQTEQFRVQAESVTGYETLAAHFPRGITDPTQVLASTERA------- Mb0208c|M.bovis_AF2122/97 LGNSLLRQFDSSHEIRTGAAAAAQALGPGALGPVQVLVRFDAG---GASA Rv0202c|M.tuberculosis_H37Rv LGNSLLRQFDSSHEIRTGAAAAAQALGPGALGPVQVLVRFDAG---GASA MLBr_02617|M.leprae_Br4923 LGNSLLRQFNSSHEIRAGVAAAAQALGPGALGPVQVLITFPDDPNTQASS MAB_4529|M.abscessus_ATCC_1997 VSNSMLRQFDSSHEIRRGIDAAAVAMGPGALGPVQVLLTFKDS-----PA :. : .** : * . : : * *. *: MUL_1909|M.ulcerans_Agy99 -------TQVRQAIGATPGVVSVTESGRSGKFGAGLTKWSVVIDAPPSSE MMAR_1673|M.marinum_M -------TQVRQAIGATPGVVSVTESGRSGKFGAGLTKWSVVIDAPPSSE MAV_3895|M.avium_104 -------AAVHQAMAATPGVVSATESGRS---ASGLTQWSVVIDAPPSSV Mflv_0224|M.gilvum_PYR-GCK -------AEVQRAITATPGVVSAFPAGAE---ADGRSQWSVVLDAEPASD Mvan_0683|M.vanbaalenii_PYR-1 -------AEVQRAITATPGVVSAIPAGSG---PGGVSQWSVVLEAAPASD MSMEG_0763|M.smegmatis_MC2_155 -------AAVQRAITDTEGVVSASPAGES---PTGLTQWSVVLGADPASD TH_3700|M.thermoresistible__bu -------NEVELAITETPGVVSAAESGRS---GTGLTQWSVVLDAEPASA Mb0208c|M.bovis_AF2122/97 PEHSQTIAAIRHRIAQAPNVVSVAPPRFAD--DNGSALLSAVLSVDPEDL Rv0202c|M.tuberculosis_H37Rv PEHSQTIAAIRHRIAQAPNVVSVAPPRFAD--DNGSALLSAVLSVDPEDL MLBr_02617|M.leprae_Br4923 PKHRQTIGAIRNRMLQAKNVMSVAPPQFAD--NNCSALLGAVLSVDPEDL MAB_4529|M.abscessus_ATCC_1997 HAHAQALETAKETIAQAPNIARVSDVSFST--DGHDALISAVLSVDPEAN . : : .: . : ..*: . * MUL_1909|M.ulcerans_Agy99 RAFTTIAALRHSASQASP----SALVGGPDAQALDVRDAAEHDRALLIPA MMAR_1673|M.marinum_M RAFTTIAALRHSASQASP----SALVGGPDAQALDVRDAAEHDRALLIPA MAV_3895|M.avium_104 RAFDIVAALRDSTRAADS----GALVGGADAAALDVRDAATHDRVLLIPA Mflv_0224|M.gilvum_PYR-GCK EAFDTIDALRESVHRADP----DALVGGSDATARDAAAAAGHDRAVVIPA Mvan_0683|M.vanbaalenii_PYR-1 AAFEAVDALRDSVHRVDP----DALVGGSDATARDAASAAAHDRAVVIPA MSMEG_0763|M.smegmatis_MC2_155 EAFETIDALRGSVQHADA----DAVVGGSDAQARDAAAAAQRDRAVVIPA TH_3700|M.thermoresistible__bu EAFETVDALRDSVRKADQ----SALVGGSDAQARDASAASTRDRLVLIPA Mb0208c|M.bovis_AF2122/97 GARDTITWMRTQLPRVAG--AAQVDVGGPTALIKDFDDRVSATQPLVLVF Rv0202c|M.tuberculosis_H37Rv GARDTITWMRTQLPRVAG--AAQVDVGGPTALIKDFDDRVSATQPLVLVF MLBr_02617|M.leprae_Br4923 GARETVDWMRTELPKVPG--AAHVNVGGPTALINDFDDRVAKTEPLMLVF MAB_4529|M.abscessus_ATCC_1997 AARDTVSWLRANVPDALENSGADINVGGPTALLFDYDTRVEHSLLGVFAF * : :* . . ***. * * :: MUL_1909|M.ulcerans_Agy99 ILAVILVVLYALLRSALAPLILLAATILGALAALG----LGGWASIHVFG MMAR_1673|M.marinum_M ILAVILVVLYALLRSALAPLILLAATILGALAALG----LGGWASIHVFG MAV_3895|M.avium_104 ILAVILIVLAVLLRSVMAPPVLLVATMLGALGALG----LGGWVSLHLFG Mflv_0224|M.gilvum_PYR-GCK ILVVVLIVLYVLLRSALAPLVLVGVTVLSSVAALG----LGGWASVHLFG Mvan_0683|M.vanbaalenii_PYR-1 ILVVVLLVLYLLLRSALAPLVLVGVTVLSALAALG----LGGWASVHVFG MSMEG_0763|M.smegmatis_MC2_155 ILVVVLAVLYILLRSAFAPLLLVGVTVLSSLAALG----LGGWASVHIFG TH_3700|M.thermoresistible__bu ILVVVLAVLYVLLRAALAPLVLVAVSLLSSLAALG----LGGWISVHVFG Mb0208c|M.bovis_AF2122/97 VAVIAFLMLLISIRSVFLAFKGVLMTLLSVAAAYGSLVMVFQWGWARGLG Rv0202c|M.tuberculosis_H37Rv VAVIAFLMLLISIRSVFLAFKGVLMTLLSVAAAYGSLVMVFQWGWARGLG MLBr_02617|M.leprae_Br4923 VALIAFVMLLISIRSVFLAFKGVLMTLLSVAAAYGSLVMVFQWGWLENLG MAB_4529|M.abscessus_ATCC_1997 VCVLAFVMLLATLRSPVLALKGVVMTVLSVAAAYGSLVIVFQWGWLEFLG : : : :* :*: . . : ::*. .* * : * . :* MUL_1909|M.ulcerans_Agy99 F---PALDNSTPLFAFLFLAALGVDYTIFLVTRAREESARNG-ARAGMVR MMAR_1673|M.marinum_M F---PALDNSTPLFAFLFLAALGVDYTIFLVTRAREESARNG-ARAGMVR MAV_3895|M.avium_104 F---PALDYTTPLFAFLFLAALGVDYTIFLVARAREEAARHG-TRQGMVE Mflv_0224|M.gilvum_PYR-GCK F---PALDNTAPLFAFLFLVALGVDYTIFLVTRAREETPGHG-TRDGIVR Mvan_0683|M.vanbaalenii_PYR-1 F---PALDYTAPLFAFLFLVALGVDYTIFLVTRAREETPEHG-TRDGIVR MSMEG_0763|M.smegmatis_MC2_155 F---PALDNGTPLFAFLFLVALGVDYTIFLVTRAREETPQYG-NREGIVR TH_3700|M.thermoresistible__bu F---PALDFATPLFALLFLVALGVDYTIFLVTRAREETVGHG-TRGGIVR Mb0208c|M.bovis_AF2122/97 FPALHSIDSTVPPLVLAMTFGLSMDYEIFLLTRIRERFLQTGQTRDAVAY Rv0202c|M.tuberculosis_H37Rv FPALHSIDSTVPPLVLAMTFGLSMDYEIFLLTRIRERFLQTGQTRDAVAY MLBr_02617|M.leprae_Br4923 FTHINSIDSTVPPLVLAMTFGLSMDYEIFLLTRIRERFLQTGHTRDAVAY MAB_4529|M.abscessus_ATCC_1997 FHKAN-IDSSIPPLALALTFGLTMDYEIFLLARVRERYLRTGDCGDAVSY * :* * :.: : .* :** ***::* **. * .: MUL_1909|M.ulcerans_Agy99 AVSATGGVITSAGIVLAAVFCVLAVLPLIVLTQLGIIVGLGILLDTFVVR MMAR_1673|M.marinum_M AVSATGGVITSAGIVLAAVFCVLAVLPLIVLTQLGIIVGLGILLDTFVVR MAV_3895|M.avium_104 AVAATGGVITSAGIVLAAVFCVLAVLPLMVLTQLGIIVGLGILLDTFVVR Mflv_0224|M.gilvum_PYR-GCK AVSATGAVISSAGIVLAAVFCVLGVLPLIVLTQVGIIVGLGILLDTFLVR Mvan_0683|M.vanbaalenii_PYR-1 AVSATGAVITSAGIVLAAVFCVLGVLPLIVLTQVGIIVGLGILLDTFVVR MSMEG_0763|M.smegmatis_MC2_155 AVSATGAVITSAGVVLAAVFCVLGVLPLIVLTQLGIIVGLGILLDTFLVR TH_3700|M.thermoresistible__bu AVSATGAVITSAGIVLAAVFCVLGVLPLIVLTQLGIIVGLGILLDTFVVR Mb0208c|M.bovis_AF2122/97 GVRTSARTITSAALIMIAVFCGFAFAGMPLVAEIGVACAVAIAVDATVVR Rv0202c|M.tuberculosis_H37Rv GVRTSARTITSAALIMIAVFCGFAFAGMPLVAEIGVACAVAIAVDATVVR MLBr_02617|M.leprae_Br4923 GVSTSARTITSAALIMIAVFVGFAFAGMPLVAEIGVACAVAIAVDVTAVR MAB_4529|M.abscessus_ATCC_1997 GVRTSARTITSAALIMIAVFIGFAFVGMPLVAQLGVACAVAIAVDATVVR .* ::. .*:**.::: *** :.. : :::::*: .:.* :*. ** MUL_1909|M.ulcerans_Agy99 TLVIPALFTLIGDRIWWPSDPKTTAHQPDLAYSHADGGSE---------- MMAR_1673|M.marinum_M TLVIPALFTLIGDRIWWPSDPKTTAHQPDLAYSHADGGSE---------- MAV_3895|M.avium_104 TLVIPALFTLVGDRIWWPNNP--SRHERSTP------------------- Mflv_0224|M.gilvum_PYR-GCK TVIIPALFTLIGPKIWWPALRQETRSDA---------------------- Mvan_0683|M.vanbaalenii_PYR-1 TVIIPALFTLIGPRIWWPALREDGPSRGR--------------------- MSMEG_0763|M.smegmatis_MC2_155 TVIIPALFTWIGPKIWWPGLRAEP-------------------------- TH_3700|M.thermoresistible__bu TVVVPALFTLIGPRMWWPALRAAE-------------------------- Mb0208c|M.bovis_AF2122/97 LVLVPALMAMFDRWNWWLPRWLAHILPSVDFDRPLPKVDLG--DVVVIPD Rv0202c|M.tuberculosis_H37Rv LVLVPALMAMFDRWNWWLPRWLAHILPSVDFDRPLPKVDLG--DVVVIPD MLBr_02617|M.leprae_Br4923 LVLVPTLMAMFAQWNWWLPRWLSRALPAVDFDKPFPPVDLN--EIVVLPA MAB_4529|M.abscessus_ATCC_1997 LVLVPALMAMFDKRNWWLPGWLDHVLPTVDFETPCVDELPGPHSESALRL :::*:*:: . ** MUL_1909|M.ulcerans_Agy99 -------------------------------------------------- MMAR_1673|M.marinum_M -------------------------------------------------- MAV_3895|M.avium_104 -------------------------------------------------- Mflv_0224|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0683|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0763|M.smegmatis_MC2_155 -------------------------------------------------- TH_3700|M.thermoresistible__bu -------------------------------------------------- Mb0208c|M.bovis_AF2122/97 DFAAAIPPSADVRMVLKSAAKLKRLAP-DAICVTDPLAFTGCGCDGKALD Rv0202c|M.tuberculosis_H37Rv DFAAAIPPSADVRMVLKSAAKLKRLAP-DAICVTDPLAFTGCGCDGKALD MLBr_02617|M.leprae_Br4923 DISATKVPCGDLRMVLKLAAKLKNLAP-DAICVADPLAFTGCGRNNKRSD MAB_4529|M.abscessus_ATCC_1997 QGSGFEEPRIDYHAIAVSAARLKRLADGGTITAPDTQAV----------- MUL_1909|M.ulcerans_Agy99 -------------------------------------------------- MMAR_1673|M.marinum_M -------------------------------------------------- MAV_3895|M.avium_104 -------------------------------------------------- Mflv_0224|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0683|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0763|M.smegmatis_MC2_155 -------------------------------------------------- TH_3700|M.thermoresistible__bu -------------------------------------------------- Mb0208c|M.bovis_AF2122/97 QVQ----------------------------------------------- Rv0202c|M.tuberculosis_H37Rv QVQ----------------------------------------------- MLBr_02617|M.leprae_Br4923 RVLPGAATQESEEDPAMGKASDSTAALTAAQVGPVTRTNGHWTARNLVIG MAB_4529|M.abscessus_ATCC_1997 -------------------------------------------------- MUL_1909|M.ulcerans_Agy99 -------------------------------------------------- MMAR_1673|M.marinum_M -------------------------------------------------- MAV_3895|M.avium_104 -------------------------------------------------- Mflv_0224|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0683|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0763|M.smegmatis_MC2_155 -------------------------------------------------- TH_3700|M.thermoresistible__bu -------------------------------------------------- Mb0208c|M.bovis_AF2122/97 LAYRNGIARAISWGQRPVHPVTVWRKRLAVALDALQTTTWECGGVQTHRA Rv0202c|M.tuberculosis_H37Rv LAYRNGIARAISWGQRPVHPVTVWRKRLAVALDALQTTTWECGGVQTHRA MLBr_02617|M.leprae_Br4923 LTHRNSITRVMPWSDRPVHPFTLWRSRFSVAIDALEAHIAVQADAPDQ-- MAB_4529|M.abscessus_ATCC_1997 LADR-------------------WRDNLTVALEALQTSKNGTDTDIVEMP MUL_1909|M.ulcerans_Agy99 -------------------------------------------------- MMAR_1673|M.marinum_M -------------------------------------------------- MAV_3895|M.avium_104 -------------------------------------------------- Mflv_0224|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0683|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0763|M.smegmatis_MC2_155 -------------------------------------------------- TH_3700|M.thermoresistible__bu -------------------------------------------------- Mb0208c|M.bovis_AF2122/97 GPGYRRRSPVETTNVALPTGDRLQIPTGAETLRFKGYLIMSRNSSHDYAD Rv0202c|M.tuberculosis_H37Rv GPGYRRRSPVETTNVALPTGDRLQIPTGAETLRFKGYLIMSRNSSHDYAD MLBr_02617|M.leprae_Br4923 -PNYQRCSPVETAHVQLPTGDRLLIPTGAETLRLVSYLIMCRNSIRDYAE MAB_4529|M.abscessus_ATCC_1997 GPLSR-VTPVEITQVKLPTGQKCVVPTDAEALRMQGLLLMRRNAERDYTE MUL_1909|M.ulcerans_Agy99 -------------------------------------------------- MMAR_1673|M.marinum_M -------------------------------------------------- MAV_3895|M.avium_104 -------------------------------------------------- Mflv_0224|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0683|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0763|M.smegmatis_MC2_155 -------------------------------------------------- TH_3700|M.thermoresistible__bu -------------------------------------------------- Mb0208c|M.bovis_AF2122/97 FADLVDTMAPETAAAVLAGMDRYYSCQAPGRQWMATQLVGRLADPQPSDL Rv0202c|M.tuberculosis_H37Rv FADLVDTMAPETAAAVLAGMDRYYSCQAPGRQWMATQLVGRLADPQPSDL MLBr_02617|M.leprae_Br4923 LADMVDAIEPETAAVVLTELDRYYSCQLPMRQWMATQLVRRLSDPHPVDL MAB_4529|M.abscessus_ATCC_1997 FARLASAMEPRMAAKVLAGIDQHYCVQSNQR-WVSSQLVRRLADPKP--- MUL_1909|M.ulcerans_Agy99 --------------------------------- MMAR_1673|M.marinum_M --------------------------------- MAV_3895|M.avium_104 --------------------------------- Mflv_0224|M.gilvum_PYR-GCK --------------------------------- Mvan_0683|M.vanbaalenii_PYR-1 --------------------------------- MSMEG_0763|M.smegmatis_MC2_155 --------------------------------- TH_3700|M.thermoresistible__bu --------------------------------- Mb0208c|M.bovis_AF2122/97 GD-QSPGADAQAKWEEVRRRCLSVAVAMLEEAR Rv0202c|M.tuberculosis_H37Rv GD-QSPGADAQAKWEEVRRRCLSVAVAMLEEAR MLBr_02617|M.leprae_Br4923 TEDQWSDPDNKAEWQDVRQRCLSVAVAMLEEAR MAB_4529|M.abscessus_ATCC_1997 -------GDGAMECPTVRRQCLSVAVAMLEDAR