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M. gilvum PYR-GCK Mflv_0224 (-)

annotation: MMPL domain-containing protein
coordinates: 209443 - 211479
length: 678

MSRRFSWVIALLVVLVSGALMGLLGGGDSSSQSPVAVPADSESARADAARAALPGGDQVPAILVVTRTDS
APLGPADLAAVDGARDRMLAAAQSGPAGPPVQVSDDGQAAVATVPMSSDLSGFDLTDTVTELRGAATDGL
PEGLQAQVTGGPAFGADIANSFSGANFTLLAVTAAVVALLLIITYRSPVLWLVPLLVIGFADRVAAVIGS
AVAEALGMSPDGSTSGITSVLVFGAGTNYALLLISRYREELGRTDSHNDAIDTAVRRAGPAIIASNATVV
LALLTLLFASSPSTRSLGVQAAAGLVVAAVFVLLVLPPALAVFGRKLFWPFIPAVGDQPLTDSGVWHRIA
AAVARRPARVAIVSIGGLALLCTGILGTPVGLSQTEQFRVEAESVRGFDTLAAHFPSGLTDPTRVIATSD
RSAEVQRAITATPGVVSAFPAGAEADGRSQWSVVLDAEPASDEAFDTIDALRESVHRADPDALVGGSDAT
ARDAAAAAGHDRAVVIPAILVVVLIVLYVLLRSALAPLVLVGVTVLSSVAALGLGGWASVHLFGFPALDN
TAPLFAFLFLVALGVDYTIFLVTRAREETPGHGTRDGIVRAVSATGAVISSAGIVLAAVFCVLGVLPLIV
LTQVGIIVGLGILLDTFLVRTVIIPALFTLIGPKIWWPALRQETRSDA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_0224--100% (678)MMPL domain-containing protein
M. gilvum PYR-GCKMflv_5232-2e-4525.74% (711) putative membrane transport protein
M. gilvum PYR-GCKMflv_0464-3e-4227.43% (525) MmpL11

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0208cmmpL113e-4327.72% (523) transmembrane transport protein MmpL11
M. tuberculosis H37RvRv0202cmmpL113e-4327.72% (523) transmembrane transport protein MmpL11
M. leprae Br4923MLBr_02617-9e-3724.71% (522) hypothetical protein MLBr_02617
M. abscessus ATCC 19977MAB_4529-3e-4225.84% (716) putative membrane protein, MmpL
M. marinum MMMAR_1673-0.064.20% (676) transmembrane transport protein
M. avium 104MAV_3895-0.064.61% (664) MmpL family protein
M. smegmatis MC2 155MSMEG_0763-0.077.54% (668) antibiotic transporter
M. thermoresistible (build 8)TH_3700-0.075.69% (469) PUTATIVE MMPL domain protein
M. ulcerans Agy99MUL_1909-0.063.46% (676) transmembrane transport protein
M. vanbaalenii PYR-1Mvan_0683-0.086.18% (673) MMPL domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0224|M.gilvum_PYR-GCK          ---------MSRRFSWVIALLVVLVSGALMGLLGGGDSSSQSPVAVPADS
Mvan_0683|M.vanbaalenii_PYR-1       ---------MSRRYSWVVALLVVLLSGALMGLLGGGDSGSQSPLIVPPDA
MSMEG_0763|M.smegmatis_MC2_155      ---------MS-----WLAVLVVIISGGLMGVLSGGDSASQSPVAVPSDA
TH_3700|M.thermoresistible__bu      --------------------------------------------------
MMAR_1673|M.marinum_M               MVWDRLAAALAAKRSWLISVGVVALATVFMVLVGGNSAAGQAPQSVPADA
MUL_1909|M.ulcerans_Agy99           MVWDRLAAALAAKRSWLISVGVVALATVFMVLVGGNSAAGQAPQSVPADV
MAV_3895|M.avium_104                MVWERVAAAVTGPRSWLLAAVAVLAGVGVMALVGPNTAAGQAPQSLPQHS
Mb0208c|M.bovis_AF2122/97           --MMRLSRNLRRCRWLVFTGWLLALVPAVYLAMTQSGNLTGGGFEVAGSQ
Rv0202c|M.tuberculosis_H37Rv        --MMRLSRNLRRCRWLVFTGWLLALVPAVYLAMTQSGNLTGGGFEVAGSQ
MLBr_02617|M.leprae_Br4923          ---MRLSSYLRRFRWLVFTGWLLALVPAIYLAMTQSGKLTGGGFEVAGSQ
MAB_4529|M.abscessus_ATCC_1997      --MMRTSDYLRRYRWLTVAVWLILIVAAVGLVAGRGEKLTGGGFEVAGSQ
                                                                                      

Mflv_0224|M.gilvum_PYR-GCK          ESARADAARAALPGGDQVPAILVVTRTDSAPLGPADLAAVDGARDRMLAA
Mvan_0683|M.vanbaalenii_PYR-1       ESARADAARAALPDGDQVPAILVVTRADAAPLTPADVAAANSARDRMLTV
MSMEG_0763|M.smegmatis_MC2_155      ESARADALRADFPGGDQAPAILVVTRADGAELGPDDIDAAAEARHRMSDA
TH_3700|M.thermoresistible__bu      --------------------------------------------------
MMAR_1673|M.marinum_M               ESAKVESELGRFPGGDRAPLILVVTRSDGTTLDAADRRAAQQAAQRMQAA
MUL_1909|M.ulcerans_Agy99           ESAKVESELGRFPGGDRAPLILVVTRSDGTTLDAADRRAAQQAAQRMQAS
MAV_3895|M.avium_104                PSARITALAGQFPGGDRTPLIVVVSRADGAVLGPADLGAARAARDRAQAA
Mb0208c|M.bovis_AF2122/97           SLLVHDQLDAHYPDRGAPALALVAAPRPDASYQDIDNAVALLRQIASELP
Rv0202c|M.tuberculosis_H37Rv        SLLVHDQLDAHYPDRGAPALALVAAPRPDASYQDIDNAVALLRQIASELP
MLBr_02617|M.leprae_Br4923          SLLVHDQLQEQYPDQGAVSLALVAAPRSDASYQDMNDAVALLRRIVSEFP
MAB_4529|M.abscessus_ATCC_1997      SLKVHDAMETGFREQGASPLALVAAPRPDATVSDMAAAVDYLKQVAAQIP
                                                                                      

Mflv_0224|M.gilvum_PYR-GCK          AQS---GPAGPPVQVSDDGQAAVATVPMSSDLSGFDLTDTVTELRGAATD
Mvan_0683|M.vanbaalenii_PYR-1       AGN---AAGGPPTQVSEDGQAAVATVPLSADLSGFALTDKVKEVRTAAAD
MSMEG_0763|M.smegmatis_MC2_155      P--------GPPMVVSDDGKAAISTVPLDATLSGFALTDEVKELRANAAE
TH_3700|M.thermoresistible__bu      --------------------------------------------------
MMAR_1673|M.marinum_M               AHPGANPRPAAPLIS-ADTKAAISVVPISANLSGLALNDAVKALREAAHE
MUL_1909|M.ulcerans_Agy99           AHPGANPRPAAPLIS-ADTKAAISVVPISANLSGLALNDAVKALREAAHE
MAV_3895|M.avium_104                AQPGAAP--AQPLTPSQDGKAALGVVPLSTTLSGLALNDAVSALRTAAAT
Mb0208c|M.bovis_AF2122/97           GVTEAPNPTQRPPQPDRPYVVSLRLDARNAGTSDVAKKLRDRIGVKGDQS
Rv0202c|M.tuberculosis_H37Rv        GVTEAPNPTQRPPQPDRPYVVSLRLDARNAGTSDVAKKLRDRIGVKGDQS
MLBr_02617|M.leprae_Br4923          GVSEVPNPTQLPPRPDRPYGVSLRLDDRNSVTSDVAKQLRTKVGIKGDQA
MAB_4529|M.abscessus_ATCC_1997      QVSVEPIPPQLTPQPDRPFVVTLRIGFDNTGATDIAKSLRKKIGVHGGQP
                                                                                      

Mflv_0224|M.gilvum_PYR-GCK          G--LPEGLQAQVTGGPAFGADIANSFSGANFTLLAVTAAVVALLLIITYR
Mvan_0683|M.vanbaalenii_PYR-1       G--LPGDLRAQVTGGPAFGADIADSFSGANVTLLAVTAAVVALLLIVTYR
MSMEG_0763|M.smegmatis_MC2_155      G--LPGDLRAEVTGGPAFGADIANSFAGANVTLLAVTAIVVALLLIVTYR
TH_3700|M.thermoresistible__bu      --------------------------------------------------
MMAR_1673|M.marinum_M               G--LPADLDAHVTGGPAFGADIANAFTNANITLLAVTASVVALLLILTYR
MUL_1909|M.ulcerans_Agy99           G--LPADLDAHVTGGPAFGADIANAFTNANITLLAVTASVVALLLILTYR
MAV_3895|M.avium_104                G--LAADLQVHVTGGPAFGADIAGAFTHANVTLLAVTASVVALLLIATYR
Mb0208c|M.bovis_AF2122/97           GQTANGKVRLYVIGQGALSAAAAANTKHDIANAERWNLPIILMVLVAVFG
Rv0202c|M.tuberculosis_H37Rv        GQTANGKVRLYVIGQGALSAAAAANTKHDIANAERWNLPIILMVLVAVFG
MLBr_02617|M.leprae_Br4923          GRTANGKVRLYVIGQGALSAAVAANSKHDIAEAERWNLPIILIVLLAVFG
MAB_4529|M.abscessus_ATCC_1997      GQIAGGRVSLYVIGQGALGAAMTEQIAGDIKKAEKWNIPVILIVLIAAFG
                                                                                      

Mflv_0224|M.gilvum_PYR-GCK          SPVLWLVPLLVIGFADRVAAVIGSAVAEALGMSPDGSTSGITSVLVFGAG
Mvan_0683|M.vanbaalenii_PYR-1       SPVLWLVPLLVIGFADRVAAVAGAAVAETLGMSPDGSTAGITSVLVFGAG
MSMEG_0763|M.smegmatis_MC2_155      SPILWLVPLLVIAFADRVGSVVGTAVASGLGMNPDGSTGGITSVLVFGAG
TH_3700|M.thermoresistible__bu      --------------------XVGSHIADAFGLMPDGSTSGITSVLVFGAG
MMAR_1673|M.marinum_M               SPVLWLLPLLVIAFADRVATTVGTAVAALTGLNFDGSTSGITSVLVFGAG
MUL_1909|M.ulcerans_Agy99           SSVLWLLPLLVIAFADRVATTVGTAVAALTGLNFDGSTSGITSVLVFGAG
MAV_3895|M.avium_104                SPVLWLVPLLVVAFADRVAAAVGTAVASLTGLSFDGATSGITSVLVFGAG
Mb0208c|M.bovis_AF2122/97           SLAAAAIPLALAVCTVVITMGLVFVLSMHTTMSVFVTST--VSMFGIALA
Rv0202c|M.tuberculosis_H37Rv        SLAAAAIPLALAVCTVVITMGLVFVLSMHTTMSVFVTST--VSMFGIALA
MLBr_02617|M.leprae_Br4923          SLAAAAVPLALGVCTVVVTMGLVDLVSMHTIMSVFVTST--VSMFGIALA
MAB_4529|M.abscessus_ATCC_1997      SLAAASLPLLLGVCTVALSVAIVLALSNITTISVFALPT--VTMIGLAVA
                                                             ::    :     .   .::: :. .

Mflv_0224|M.gilvum_PYR-GCK          TNYALLLISRYREELGR-----TDSHNDAIDTAVRRAGPAIIASNATVVL
Mvan_0683|M.vanbaalenii_PYR-1       TNYALLLISRYREELGR-----SESHRDALGTAVRRAGPAIIASNATVVL
MSMEG_0763|M.smegmatis_MC2_155      TNYALLLISRYREELGR-----TENHRDALQASVRAAAPAIIASNATVVL
TH_3700|M.thermoresistible__bu      TNYSLLLISRYREELGRGGEQAHPDHHAALRVAVRNAGPAILASNATVVL
MMAR_1673|M.marinum_M               TNYALLLISRYRQELPV-----HRDHRDALARAVRMAGPAIAASNATVVL
MUL_1909|M.ulcerans_Agy99           TNYALLLISRYRQELPV-----HRDHRDALARAVRMAGPPIAASNATVVL
MAV_3895|M.avium_104                TNYALLLISRYRQELRR-----HAGHRDALRRAVHRAGPAIVASNATVVL
Mb0208c|M.bovis_AF2122/97           VDYSLFILMRYREELRC-----GRRPPDAVDAAMATSGLAVVLSGMTVIA
Rv0202c|M.tuberculosis_H37Rv        VDYSLFILMRYREELRC-----GRRPPDAVDAAMATSGLAVVLSGMTVIA
MLBr_02617|M.leprae_Br4923          VDYSLFILMRFREELRS-----GRQPQEAVDAAMATSGLAVVLSGMTVIA
MAB_4529|M.abscessus_ATCC_1997      VDYSLFILMRYREELNS-----GKNRQEAIAGAMATSGLTVTFSGLTVIA
                                    .:*:*::: *:*:**             *:  ::  :. .:  *. **: 

Mflv_0224|M.gilvum_PYR-GCK          ALLTLLFASSPSTRSLGVQAAAGLVVAAVFVLLVLPPALAVFGRKLFWP-
Mvan_0683|M.vanbaalenii_PYR-1       ALLTLLLASSPSTRSLGVQAASGLVIAAVFVLLVLPPALGVFGRKLFWP-
MSMEG_0763|M.smegmatis_MC2_155      ALLTLLFATAPSNRSLGVQAASGLVVAAVFVLIVLPPLLALCGKRLFWP-
TH_3700|M.thermoresistible__bu      ALLTLLFGVVPSTRSLGLQAASGLVVAAVFVLLVLPPLLALFGRRLFWP-
MMAR_1673|M.marinum_M               ALLTLVFAATPSTRSLGALAACGLVVAAVSVLVVLPPLLALCGRRLFWP-
MUL_1909|M.ulcerans_Agy99           ALLTLVFAATPSNRSLGALAACGVVVAAVSVLVVLPPLLALCGRRLFWP-
MAV_3895|M.avium_104                ALLTLLLAATPSTRSLGALAACGLVIAAVSVLVVLPPLLAVCGRRLFWP-
Mb0208c|M.bovis_AF2122/97           SLTGIYLINTPALRSMATGAILAVAVAMLTSATLTPAVLATFARAAAKRS
Rv0202c|M.tuberculosis_H37Rv        SLTGIYLINTPALRSMATGAILAVAVAMLTSATLTPAVLATFARAAAKRS
MLBr_02617|M.leprae_Br4923          SLTGIYLINTAALKSMATGAILAVAIAMLASITLTPAALATFGRAAVKRS
MAB_4529|M.abscessus_ATCC_1997      ALAGIYLIGTPALASMASGAIIVVAIAVLTSTTLMPALLAIFGKAAANQS
                                    :*  : :   .:  *:.  *   :.:* :    : *. *.  .:      

Mflv_0224|M.gilvum_PYR-GCK          -FIPAVGDQPLTDSGVWHRIAAAVARRPARVAIVSIGGLALLCTGILGTP
Mvan_0683|M.vanbaalenii_PYR-1       -FIPQVGAKPLTDSGVWHRVAAAVARRPARVAIVSIGGLALLCTGLLGTP
MSMEG_0763|M.smegmatis_MC2_155      -FIPKVGATALTESGVWHRIADTVARRPARVVVVSVAGLALLCTALLTTP
TH_3700|M.thermoresistible__bu      -FVPQPGAEPLTDSGLWRRIADWVADRPGPVAAATLAVLAVMCTGLLGTP
MMAR_1673|M.marinum_M               -FIPRAEDTTALDSGFWHAVAQRVARRPAPVALVTVALLIGLATGLLGTR
MUL_1909|M.ulcerans_Agy99           -FIPRAEDTTALDSGFWHAVAQRVARRPAPVALVTVALLIGLATGLLGTR
MAV_3895|M.avium_104                -FIP--VDRPATESGAWRRVAEWVAGRPALVAVAAVAVLAALGGGLWGTR
Mb0208c|M.bovis_AF2122/97           ALVHWSRRPASTQSWFWSRWVGWVMRRPWITALAASTVLLVMAAPATLMV
Rv0202c|M.tuberculosis_H37Rv        ALVHWSRRPASTQSWFWSRWVGWVMRRPWITALAASTVLLVMAAPATLMV
MLBr_02617|M.leprae_Br4923          VLMHWSQRSECTQSLFWTRWVGWVMHRPWISASAASTILIIMATPVTSMM
MAB_4529|M.abscessus_ATCC_1997      RFLRVSPLRKHSIP-FWRKWTQQVMRRPWLSALGASIFLLALAAPSLQMH
                                     ::          .  *   .  *  **   .  :   *  :        

Mflv_0224|M.gilvum_PYR-GCK          VGLSQTEQFRVEAESVRGFDTLAAHFPSGLTDPTRVIATSDRS-------
Mvan_0683|M.vanbaalenii_PYR-1       VGLSQTEQFRVQAESVSGFETLAAHFPSGLTAPARVIASTDRA-------
MSMEG_0763|M.smegmatis_MC2_155      IGLTQTEQFRVQAESVSGFETVSAHFPSGLTDPTRVIASTDKA-------
TH_3700|M.thermoresistible__bu      IGLSQTEQFRVQAESVTGYETLAAHFPRGITDPTQVLASTERA-------
MMAR_1673|M.marinum_M               IGLSQTEQFRVKADSVSGYDVVAQHFPAGLVNPTLVVAPSAQA-------
MUL_1909|M.ulcerans_Agy99           IGLSQTEQFRVKADSVSGYDVVAQHFPAGLVNPTLVVAPSAQA-------
MAV_3895|M.avium_104                IGLSQTEQFRVRADSVAGYHVLAQHFPAGLANPTLVVADTGHA-------
Mb0208c|M.bovis_AF2122/97           LGNSLLRQFDSSHEIRTGAAAAAQALGPGALGPVQVLVRFDAG---GASA
Rv0202c|M.tuberculosis_H37Rv        LGNSLLRQFDSSHEIRTGAAAAAQALGPGALGPVQVLVRFDAG---GASA
MLBr_02617|M.leprae_Br4923          LGNSLLRQFNSSHEIRAGVAAAAQALGPGALGPVQVLITFPDDPNTQASS
MAB_4529|M.abscessus_ATCC_1997      VSNSMLRQFDSSHEIRRGIDAAAVAMGPGALGPVQVLLTFKDS-----PA
                                    :. :  .**    :   *  . :  :  *   *. *:             

Mflv_0224|M.gilvum_PYR-GCK          -------AEVQRAITATPGVVSAFPAGAE---ADGRSQWSVVLDAEPASD
Mvan_0683|M.vanbaalenii_PYR-1       -------AEVQRAITATPGVVSAIPAGSG---PGGVSQWSVVLEAAPASD
MSMEG_0763|M.smegmatis_MC2_155      -------AAVQRAITDTEGVVSASPAGES---PTGLTQWSVVLGADPASD
TH_3700|M.thermoresistible__bu      -------NEVELAITETPGVVSAAESGRS---GTGLTQWSVVLDAEPASA
MMAR_1673|M.marinum_M               -------TQVRQAIGATPGVVSVTESGRSGKFGAGLTKWSVVIDAPPSSE
MUL_1909|M.ulcerans_Agy99           -------TQVRQAIGATPGVVSVTESGRSGKFGAGLTKWSVVIDAPPSSE
MAV_3895|M.avium_104                -------AAVHQAMAATPGVVSATESGRS---ASGLTQWSVVIDAPPSSV
Mb0208c|M.bovis_AF2122/97           PEHSQTIAAIRHRIAQAPNVVSVAPPRFAD--DNGSALLSAVLSVDPEDL
Rv0202c|M.tuberculosis_H37Rv        PEHSQTIAAIRHRIAQAPNVVSVAPPRFAD--DNGSALLSAVLSVDPEDL
MLBr_02617|M.leprae_Br4923          PKHRQTIGAIRNRMLQAKNVMSVAPPQFAD--NNCSALLGAVLSVDPEDL
MAB_4529|M.abscessus_ATCC_1997      HAHAQALETAKETIAQAPNIARVSDVSFST--DGHDALISAVLSVDPEAN
                                              .  :  : .:  .             :  ..*: . *   

Mflv_0224|M.gilvum_PYR-GCK          EAFDTIDALRESVHRADP----DALVGGSDATARDAAAAAGHDRAVVIPA
Mvan_0683|M.vanbaalenii_PYR-1       AAFEAVDALRDSVHRVDP----DALVGGSDATARDAASAAAHDRAVVIPA
MSMEG_0763|M.smegmatis_MC2_155      EAFETIDALRGSVQHADA----DAVVGGSDAQARDAAAAAQRDRAVVIPA
TH_3700|M.thermoresistible__bu      EAFETVDALRDSVRKADQ----SALVGGSDAQARDASAASTRDRLVLIPA
MMAR_1673|M.marinum_M               RAFTTIAALRHSASQASP----SALVGGPDAQALDVRDAAEHDRALLIPA
MUL_1909|M.ulcerans_Agy99           RAFTTIAALRHSASQASP----SALVGGPDAQALDVRDAAEHDRALLIPA
MAV_3895|M.avium_104                RAFDIVAALRDSTRAADS----GALVGGADAAALDVRDAATHDRVLLIPA
Mb0208c|M.bovis_AF2122/97           GARDTITWMRTQLPRVAG--AAQVDVGGPTALIKDFDDRVSATQPLVLVF
Rv0202c|M.tuberculosis_H37Rv        GARDTITWMRTQLPRVAG--AAQVDVGGPTALIKDFDDRVSATQPLVLVF
MLBr_02617|M.leprae_Br4923          GARETVDWMRTELPKVPG--AAHVNVGGPTALINDFDDRVAKTEPLMLVF
MAB_4529|M.abscessus_ATCC_1997      AARDTVSWLRANVPDALENSGADINVGGPTALLFDYDTRVEHSLLGVFAF
                                     *   :  :* .   .         ***. *   *           ::  

Mflv_0224|M.gilvum_PYR-GCK          ILVVVLIVLYVLLRSALAPLVLVGVTVLSSVAALG----LGGWASVHLFG
Mvan_0683|M.vanbaalenii_PYR-1       ILVVVLLVLYLLLRSALAPLVLVGVTVLSALAALG----LGGWASVHVFG
MSMEG_0763|M.smegmatis_MC2_155      ILVVVLAVLYILLRSAFAPLLLVGVTVLSSLAALG----LGGWASVHIFG
TH_3700|M.thermoresistible__bu      ILVVVLAVLYVLLRAALAPLVLVAVSLLSSLAALG----LGGWISVHVFG
MMAR_1673|M.marinum_M               ILAVILVVLYALLRSALAPLILLAATILGALAALG----LGGWASIHVFG
MUL_1909|M.ulcerans_Agy99           ILAVILVVLYALLRSALAPLILLAATILGALAALG----LGGWASIHVFG
MAV_3895|M.avium_104                ILAVILIVLAVLLRSVMAPPVLLVATMLGALGALG----LGGWVSLHLFG
Mb0208c|M.bovis_AF2122/97           VAVIAFLMLLISIRSVFLAFKGVLMTLLSVAAAYGSLVMVFQWGWARGLG
Rv0202c|M.tuberculosis_H37Rv        VAVIAFLMLLISIRSVFLAFKGVLMTLLSVAAAYGSLVMVFQWGWARGLG
MLBr_02617|M.leprae_Br4923          VALIAFVMLLISIRSVFLAFKGVLMTLLSVAAAYGSLVMVFQWGWLENLG
MAB_4529|M.abscessus_ATCC_1997      VCVLAFVMLLATLRSPVLALKGVVMTVLSVAAAYGSLVIVFQWGWLEFLG
                                    :  : : :*   :*: . .   :  ::*.  .* *    :  *   . :*

Mflv_0224|M.gilvum_PYR-GCK          F---PALDNTAPLFAFLFLVALGVDYTIFLVTRAREETPGHG-TRDGIVR
Mvan_0683|M.vanbaalenii_PYR-1       F---PALDYTAPLFAFLFLVALGVDYTIFLVTRAREETPEHG-TRDGIVR
MSMEG_0763|M.smegmatis_MC2_155      F---PALDNGTPLFAFLFLVALGVDYTIFLVTRAREETPQYG-NREGIVR
TH_3700|M.thermoresistible__bu      F---PALDFATPLFALLFLVALGVDYTIFLVTRAREETVGHG-TRGGIVR
MMAR_1673|M.marinum_M               F---PALDNSTPLFAFLFLAALGVDYTIFLVTRAREESARNG-ARAGMVR
MUL_1909|M.ulcerans_Agy99           F---PALDNSTPLFAFLFLAALGVDYTIFLVTRAREESARNG-ARAGMVR
MAV_3895|M.avium_104                F---PALDYTTPLFAFLFLAALGVDYTIFLVARAREEAARHG-TRQGMVE
Mb0208c|M.bovis_AF2122/97           FPALHSIDSTVPPLVLAMTFGLSMDYEIFLLTRIRERFLQTGQTRDAVAY
Rv0202c|M.tuberculosis_H37Rv        FPALHSIDSTVPPLVLAMTFGLSMDYEIFLLTRIRERFLQTGQTRDAVAY
MLBr_02617|M.leprae_Br4923          FTHINSIDSTVPPLVLAMTFGLSMDYEIFLLTRIRERFLQTGHTRDAVAY
MAB_4529|M.abscessus_ATCC_1997      FHKAN-IDSSIPPLALALTFGLTMDYEIFLLARVRERYLRTGDCGDAVSY
                                    *     :*   * :.: :  .* :** ***::* **.    *    .:  

Mflv_0224|M.gilvum_PYR-GCK          AVSATGAVISSAGIVLAAVFCVLGVLPLIVLTQVGIIVGLGILLDTFLVR
Mvan_0683|M.vanbaalenii_PYR-1       AVSATGAVITSAGIVLAAVFCVLGVLPLIVLTQVGIIVGLGILLDTFVVR
MSMEG_0763|M.smegmatis_MC2_155      AVSATGAVITSAGVVLAAVFCVLGVLPLIVLTQLGIIVGLGILLDTFLVR
TH_3700|M.thermoresistible__bu      AVSATGAVITSAGIVLAAVFCVLGVLPLIVLTQLGIIVGLGILLDTFVVR
MMAR_1673|M.marinum_M               AVSATGGVITSAGIVLAAVFCVLAVLPLIVLTQLGIIVGLGILLDTFVVR
MUL_1909|M.ulcerans_Agy99           AVSATGGVITSAGIVLAAVFCVLAVLPLIVLTQLGIIVGLGILLDTFVVR
MAV_3895|M.avium_104                AVAATGGVITSAGIVLAAVFCVLAVLPLMVLTQLGIIVGLGILLDTFVVR
Mb0208c|M.bovis_AF2122/97           GVRTSARTITSAALIMIAVFCGFAFAGMPLVAEIGVACAVAIAVDATVVR
Rv0202c|M.tuberculosis_H37Rv        GVRTSARTITSAALIMIAVFCGFAFAGMPLVAEIGVACAVAIAVDATVVR
MLBr_02617|M.leprae_Br4923          GVSTSARTITSAALIMIAVFVGFAFAGMPLVAEIGVACAVAIAVDVTAVR
MAB_4529|M.abscessus_ATCC_1997      GVRTSARTITSAALIMIAVFIGFAFVGMPLVAQLGVACAVAIAVDATVVR
                                    .* ::. .*:**.::: ***  :..  : :::::*:  .:.* :*.  **

Mflv_0224|M.gilvum_PYR-GCK          TVIIPALFTLIGPKIWWPALRQETRSDA----------------------
Mvan_0683|M.vanbaalenii_PYR-1       TVIIPALFTLIGPRIWWPALREDGPSRGR---------------------
MSMEG_0763|M.smegmatis_MC2_155      TVIIPALFTWIGPKIWWPGLRAEP--------------------------
TH_3700|M.thermoresistible__bu      TVVVPALFTLIGPRMWWPALRAAE--------------------------
MMAR_1673|M.marinum_M               TLVIPALFTLIGDRIWWPSDPKTTAHQPDLAYSHADGGSE----------
MUL_1909|M.ulcerans_Agy99           TLVIPALFTLIGDRIWWPSDPKTTAHQPDLAYSHADGGSE----------
MAV_3895|M.avium_104                TLVIPALFTLVGDRIWWPNNP--SRHERSTP-------------------
Mb0208c|M.bovis_AF2122/97           LVLVPALMAMFDRWNWWLPRWLAHILPSVDFDRPLPKVDLG--DVVVIPD
Rv0202c|M.tuberculosis_H37Rv        LVLVPALMAMFDRWNWWLPRWLAHILPSVDFDRPLPKVDLG--DVVVIPD
MLBr_02617|M.leprae_Br4923          LVLVPTLMAMFAQWNWWLPRWLSRALPAVDFDKPFPPVDLN--EIVVLPA
MAB_4529|M.abscessus_ATCC_1997      LVLVPALMAMFDKRNWWLPGWLDHVLPTVDFETPCVDELPGPHSESALRL
                                     :::*:*:: .    **                                 

Mflv_0224|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0683|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0763|M.smegmatis_MC2_155      --------------------------------------------------
TH_3700|M.thermoresistible__bu      --------------------------------------------------
MMAR_1673|M.marinum_M               --------------------------------------------------
MUL_1909|M.ulcerans_Agy99           --------------------------------------------------
MAV_3895|M.avium_104                --------------------------------------------------
Mb0208c|M.bovis_AF2122/97           DFAAAIPPSADVRMVLKSAAKLKRLAP-DAICVTDPLAFTGCGCDGKALD
Rv0202c|M.tuberculosis_H37Rv        DFAAAIPPSADVRMVLKSAAKLKRLAP-DAICVTDPLAFTGCGCDGKALD
MLBr_02617|M.leprae_Br4923          DISATKVPCGDLRMVLKLAAKLKNLAP-DAICVADPLAFTGCGRNNKRSD
MAB_4529|M.abscessus_ATCC_1997      QGSGFEEPRIDYHAIAVSAARLKRLADGGTITAPDTQAV-----------
                                                                                      

Mflv_0224|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0683|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0763|M.smegmatis_MC2_155      --------------------------------------------------
TH_3700|M.thermoresistible__bu      --------------------------------------------------
MMAR_1673|M.marinum_M               --------------------------------------------------
MUL_1909|M.ulcerans_Agy99           --------------------------------------------------
MAV_3895|M.avium_104                --------------------------------------------------
Mb0208c|M.bovis_AF2122/97           QVQ-----------------------------------------------
Rv0202c|M.tuberculosis_H37Rv        QVQ-----------------------------------------------
MLBr_02617|M.leprae_Br4923          RVLPGAATQESEEDPAMGKASDSTAALTAAQVGPVTRTNGHWTARNLVIG
MAB_4529|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mflv_0224|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0683|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0763|M.smegmatis_MC2_155      --------------------------------------------------
TH_3700|M.thermoresistible__bu      --------------------------------------------------
MMAR_1673|M.marinum_M               --------------------------------------------------
MUL_1909|M.ulcerans_Agy99           --------------------------------------------------
MAV_3895|M.avium_104                --------------------------------------------------
Mb0208c|M.bovis_AF2122/97           LAYRNGIARAISWGQRPVHPVTVWRKRLAVALDALQTTTWECGGVQTHRA
Rv0202c|M.tuberculosis_H37Rv        LAYRNGIARAISWGQRPVHPVTVWRKRLAVALDALQTTTWECGGVQTHRA
MLBr_02617|M.leprae_Br4923          LTHRNSITRVMPWSDRPVHPFTLWRSRFSVAIDALEAHIAVQADAPDQ--
MAB_4529|M.abscessus_ATCC_1997      LADR-------------------WRDNLTVALEALQTSKNGTDTDIVEMP
                                                                                      

Mflv_0224|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0683|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0763|M.smegmatis_MC2_155      --------------------------------------------------
TH_3700|M.thermoresistible__bu      --------------------------------------------------
MMAR_1673|M.marinum_M               --------------------------------------------------
MUL_1909|M.ulcerans_Agy99           --------------------------------------------------
MAV_3895|M.avium_104                --------------------------------------------------
Mb0208c|M.bovis_AF2122/97           GPGYRRRSPVETTNVALPTGDRLQIPTGAETLRFKGYLIMSRNSSHDYAD
Rv0202c|M.tuberculosis_H37Rv        GPGYRRRSPVETTNVALPTGDRLQIPTGAETLRFKGYLIMSRNSSHDYAD
MLBr_02617|M.leprae_Br4923          -PNYQRCSPVETAHVQLPTGDRLLIPTGAETLRLVSYLIMCRNSIRDYAE
MAB_4529|M.abscessus_ATCC_1997      GPLSR-VTPVEITQVKLPTGQKCVVPTDAEALRMQGLLLMRRNAERDYTE
                                                                                      

Mflv_0224|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0683|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0763|M.smegmatis_MC2_155      --------------------------------------------------
TH_3700|M.thermoresistible__bu      --------------------------------------------------
MMAR_1673|M.marinum_M               --------------------------------------------------
MUL_1909|M.ulcerans_Agy99           --------------------------------------------------
MAV_3895|M.avium_104                --------------------------------------------------
Mb0208c|M.bovis_AF2122/97           FADLVDTMAPETAAAVLAGMDRYYSCQAPGRQWMATQLVGRLADPQPSDL
Rv0202c|M.tuberculosis_H37Rv        FADLVDTMAPETAAAVLAGMDRYYSCQAPGRQWMATQLVGRLADPQPSDL
MLBr_02617|M.leprae_Br4923          LADMVDAIEPETAAVVLTELDRYYSCQLPMRQWMATQLVRRLSDPHPVDL
MAB_4529|M.abscessus_ATCC_1997      FARLASAMEPRMAAKVLAGIDQHYCVQSNQR-WVSSQLVRRLADPKP---
                                                                                      

Mflv_0224|M.gilvum_PYR-GCK          ---------------------------------
Mvan_0683|M.vanbaalenii_PYR-1       ---------------------------------
MSMEG_0763|M.smegmatis_MC2_155      ---------------------------------
TH_3700|M.thermoresistible__bu      ---------------------------------
MMAR_1673|M.marinum_M               ---------------------------------
MUL_1909|M.ulcerans_Agy99           ---------------------------------
MAV_3895|M.avium_104                ---------------------------------
Mb0208c|M.bovis_AF2122/97           GD-QSPGADAQAKWEEVRRRCLSVAVAMLEEAR
Rv0202c|M.tuberculosis_H37Rv        GD-QSPGADAQAKWEEVRRRCLSVAVAMLEEAR
MLBr_02617|M.leprae_Br4923          TEDQWSDPDNKAEWQDVRQRCLSVAVAMLEEAR
MAB_4529|M.abscessus_ATCC_1997      -------GDGAMECPTVRRQCLSVAVAMLEDAR