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MSRRFSWVIALLVVLVSGALMGLLGGGDSSSQSPVAVPADSESARADAARAALPGGDQVPAILVVTRTDS APLGPADLAAVDGARDRMLAAAQSGPAGPPVQVSDDGQAAVATVPMSSDLSGFDLTDTVTELRGAATDGL PEGLQAQVTGGPAFGADIANSFSGANFTLLAVTAAVVALLLIITYRSPVLWLVPLLVIGFADRVAAVIGS AVAEALGMSPDGSTSGITSVLVFGAGTNYALLLISRYREELGRTDSHNDAIDTAVRRAGPAIIASNATVV LALLTLLFASSPSTRSLGVQAAAGLVVAAVFVLLVLPPALAVFGRKLFWPFIPAVGDQPLTDSGVWHRIA AAVARRPARVAIVSIGGLALLCTGILGTPVGLSQTEQFRVEAESVRGFDTLAAHFPSGLTDPTRVIATSD RSAEVQRAITATPGVVSAFPAGAEADGRSQWSVVLDAEPASDEAFDTIDALRESVHRADPDALVGGSDAT ARDAAAAAGHDRAVVIPAILVVVLIVLYVLLRSALAPLVLVGVTVLSSVAALGLGGWASVHLFGFPALDN TAPLFAFLFLVALGVDYTIFLVTRAREETPGHGTRDGIVRAVSATGAVISSAGIVLAAVFCVLGVLPLIV LTQVGIIVGLGILLDTFLVRTVIIPALFTLIGPKIWWPALRQETRSDA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_0224 | - | - | 100% (678) | MMPL domain-containing protein |
M. gilvum PYR-GCK | Mflv_5232 | - | 2e-45 | 25.74% (711) | putative membrane transport protein |
M. gilvum PYR-GCK | Mflv_0464 | - | 3e-42 | 27.43% (525) | MmpL11 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0208c | mmpL11 | 3e-43 | 27.72% (523) | transmembrane transport protein MmpL11 |
M. tuberculosis H37Rv | Rv0202c | mmpL11 | 3e-43 | 27.72% (523) | transmembrane transport protein MmpL11 |
M. leprae Br4923 | MLBr_02617 | - | 9e-37 | 24.71% (522) | hypothetical protein MLBr_02617 |
M. abscessus ATCC 19977 | MAB_4529 | - | 3e-42 | 25.84% (716) | putative membrane protein, MmpL |
M. marinum M | MMAR_1673 | - | 0.0 | 64.20% (676) | transmembrane transport protein |
M. avium 104 | MAV_3895 | - | 0.0 | 64.61% (664) | MmpL family protein |
M. smegmatis MC2 155 | MSMEG_0763 | - | 0.0 | 77.54% (668) | antibiotic transporter |
M. thermoresistible (build 8) | TH_3700 | - | 0.0 | 75.69% (469) | PUTATIVE MMPL domain protein |
M. ulcerans Agy99 | MUL_1909 | - | 0.0 | 63.46% (676) | transmembrane transport protein |
M. vanbaalenii PYR-1 | Mvan_0683 | - | 0.0 | 86.18% (673) | MMPL domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_0224|M.gilvum_PYR-GCK ---------MSRRFSWVIALLVVLVSGALMGLLGGGDSSSQSPVAVPADS Mvan_0683|M.vanbaalenii_PYR-1 ---------MSRRYSWVVALLVVLLSGALMGLLGGGDSGSQSPLIVPPDA MSMEG_0763|M.smegmatis_MC2_155 ---------MS-----WLAVLVVIISGGLMGVLSGGDSASQSPVAVPSDA TH_3700|M.thermoresistible__bu -------------------------------------------------- MMAR_1673|M.marinum_M MVWDRLAAALAAKRSWLISVGVVALATVFMVLVGGNSAAGQAPQSVPADA MUL_1909|M.ulcerans_Agy99 MVWDRLAAALAAKRSWLISVGVVALATVFMVLVGGNSAAGQAPQSVPADV MAV_3895|M.avium_104 MVWERVAAAVTGPRSWLLAAVAVLAGVGVMALVGPNTAAGQAPQSLPQHS Mb0208c|M.bovis_AF2122/97 --MMRLSRNLRRCRWLVFTGWLLALVPAVYLAMTQSGNLTGGGFEVAGSQ Rv0202c|M.tuberculosis_H37Rv --MMRLSRNLRRCRWLVFTGWLLALVPAVYLAMTQSGNLTGGGFEVAGSQ MLBr_02617|M.leprae_Br4923 ---MRLSSYLRRFRWLVFTGWLLALVPAIYLAMTQSGKLTGGGFEVAGSQ MAB_4529|M.abscessus_ATCC_1997 --MMRTSDYLRRYRWLTVAVWLILIVAAVGLVAGRGEKLTGGGFEVAGSQ Mflv_0224|M.gilvum_PYR-GCK ESARADAARAALPGGDQVPAILVVTRTDSAPLGPADLAAVDGARDRMLAA Mvan_0683|M.vanbaalenii_PYR-1 ESARADAARAALPDGDQVPAILVVTRADAAPLTPADVAAANSARDRMLTV MSMEG_0763|M.smegmatis_MC2_155 ESARADALRADFPGGDQAPAILVVTRADGAELGPDDIDAAAEARHRMSDA TH_3700|M.thermoresistible__bu -------------------------------------------------- MMAR_1673|M.marinum_M ESAKVESELGRFPGGDRAPLILVVTRSDGTTLDAADRRAAQQAAQRMQAA MUL_1909|M.ulcerans_Agy99 ESAKVESELGRFPGGDRAPLILVVTRSDGTTLDAADRRAAQQAAQRMQAS MAV_3895|M.avium_104 PSARITALAGQFPGGDRTPLIVVVSRADGAVLGPADLGAARAARDRAQAA Mb0208c|M.bovis_AF2122/97 SLLVHDQLDAHYPDRGAPALALVAAPRPDASYQDIDNAVALLRQIASELP Rv0202c|M.tuberculosis_H37Rv SLLVHDQLDAHYPDRGAPALALVAAPRPDASYQDIDNAVALLRQIASELP MLBr_02617|M.leprae_Br4923 SLLVHDQLQEQYPDQGAVSLALVAAPRSDASYQDMNDAVALLRRIVSEFP MAB_4529|M.abscessus_ATCC_1997 SLKVHDAMETGFREQGASPLALVAAPRPDATVSDMAAAVDYLKQVAAQIP Mflv_0224|M.gilvum_PYR-GCK AQS---GPAGPPVQVSDDGQAAVATVPMSSDLSGFDLTDTVTELRGAATD Mvan_0683|M.vanbaalenii_PYR-1 AGN---AAGGPPTQVSEDGQAAVATVPLSADLSGFALTDKVKEVRTAAAD MSMEG_0763|M.smegmatis_MC2_155 P--------GPPMVVSDDGKAAISTVPLDATLSGFALTDEVKELRANAAE TH_3700|M.thermoresistible__bu -------------------------------------------------- MMAR_1673|M.marinum_M AHPGANPRPAAPLIS-ADTKAAISVVPISANLSGLALNDAVKALREAAHE MUL_1909|M.ulcerans_Agy99 AHPGANPRPAAPLIS-ADTKAAISVVPISANLSGLALNDAVKALREAAHE MAV_3895|M.avium_104 AQPGAAP--AQPLTPSQDGKAALGVVPLSTTLSGLALNDAVSALRTAAAT Mb0208c|M.bovis_AF2122/97 GVTEAPNPTQRPPQPDRPYVVSLRLDARNAGTSDVAKKLRDRIGVKGDQS Rv0202c|M.tuberculosis_H37Rv GVTEAPNPTQRPPQPDRPYVVSLRLDARNAGTSDVAKKLRDRIGVKGDQS MLBr_02617|M.leprae_Br4923 GVSEVPNPTQLPPRPDRPYGVSLRLDDRNSVTSDVAKQLRTKVGIKGDQA MAB_4529|M.abscessus_ATCC_1997 QVSVEPIPPQLTPQPDRPFVVTLRIGFDNTGATDIAKSLRKKIGVHGGQP Mflv_0224|M.gilvum_PYR-GCK G--LPEGLQAQVTGGPAFGADIANSFSGANFTLLAVTAAVVALLLIITYR Mvan_0683|M.vanbaalenii_PYR-1 G--LPGDLRAQVTGGPAFGADIADSFSGANVTLLAVTAAVVALLLIVTYR MSMEG_0763|M.smegmatis_MC2_155 G--LPGDLRAEVTGGPAFGADIANSFAGANVTLLAVTAIVVALLLIVTYR TH_3700|M.thermoresistible__bu -------------------------------------------------- MMAR_1673|M.marinum_M G--LPADLDAHVTGGPAFGADIANAFTNANITLLAVTASVVALLLILTYR MUL_1909|M.ulcerans_Agy99 G--LPADLDAHVTGGPAFGADIANAFTNANITLLAVTASVVALLLILTYR MAV_3895|M.avium_104 G--LAADLQVHVTGGPAFGADIAGAFTHANVTLLAVTASVVALLLIATYR Mb0208c|M.bovis_AF2122/97 GQTANGKVRLYVIGQGALSAAAAANTKHDIANAERWNLPIILMVLVAVFG Rv0202c|M.tuberculosis_H37Rv GQTANGKVRLYVIGQGALSAAAAANTKHDIANAERWNLPIILMVLVAVFG MLBr_02617|M.leprae_Br4923 GRTANGKVRLYVIGQGALSAAVAANSKHDIAEAERWNLPIILIVLLAVFG MAB_4529|M.abscessus_ATCC_1997 GQIAGGRVSLYVIGQGALGAAMTEQIAGDIKKAEKWNIPVILIVLIAAFG Mflv_0224|M.gilvum_PYR-GCK SPVLWLVPLLVIGFADRVAAVIGSAVAEALGMSPDGSTSGITSVLVFGAG Mvan_0683|M.vanbaalenii_PYR-1 SPVLWLVPLLVIGFADRVAAVAGAAVAETLGMSPDGSTAGITSVLVFGAG MSMEG_0763|M.smegmatis_MC2_155 SPILWLVPLLVIAFADRVGSVVGTAVASGLGMNPDGSTGGITSVLVFGAG TH_3700|M.thermoresistible__bu --------------------XVGSHIADAFGLMPDGSTSGITSVLVFGAG MMAR_1673|M.marinum_M SPVLWLLPLLVIAFADRVATTVGTAVAALTGLNFDGSTSGITSVLVFGAG MUL_1909|M.ulcerans_Agy99 SSVLWLLPLLVIAFADRVATTVGTAVAALTGLNFDGSTSGITSVLVFGAG MAV_3895|M.avium_104 SPVLWLVPLLVVAFADRVAAAVGTAVASLTGLSFDGATSGITSVLVFGAG Mb0208c|M.bovis_AF2122/97 SLAAAAIPLALAVCTVVITMGLVFVLSMHTTMSVFVTST--VSMFGIALA Rv0202c|M.tuberculosis_H37Rv SLAAAAIPLALAVCTVVITMGLVFVLSMHTTMSVFVTST--VSMFGIALA MLBr_02617|M.leprae_Br4923 SLAAAAVPLALGVCTVVVTMGLVDLVSMHTIMSVFVTST--VSMFGIALA MAB_4529|M.abscessus_ATCC_1997 SLAAASLPLLLGVCTVALSVAIVLALSNITTISVFALPT--VTMIGLAVA :: : . .::: :. . Mflv_0224|M.gilvum_PYR-GCK TNYALLLISRYREELGR-----TDSHNDAIDTAVRRAGPAIIASNATVVL Mvan_0683|M.vanbaalenii_PYR-1 TNYALLLISRYREELGR-----SESHRDALGTAVRRAGPAIIASNATVVL MSMEG_0763|M.smegmatis_MC2_155 TNYALLLISRYREELGR-----TENHRDALQASVRAAAPAIIASNATVVL TH_3700|M.thermoresistible__bu TNYSLLLISRYREELGRGGEQAHPDHHAALRVAVRNAGPAILASNATVVL MMAR_1673|M.marinum_M TNYALLLISRYRQELPV-----HRDHRDALARAVRMAGPAIAASNATVVL MUL_1909|M.ulcerans_Agy99 TNYALLLISRYRQELPV-----HRDHRDALARAVRMAGPPIAASNATVVL MAV_3895|M.avium_104 TNYALLLISRYRQELRR-----HAGHRDALRRAVHRAGPAIVASNATVVL Mb0208c|M.bovis_AF2122/97 VDYSLFILMRYREELRC-----GRRPPDAVDAAMATSGLAVVLSGMTVIA Rv0202c|M.tuberculosis_H37Rv VDYSLFILMRYREELRC-----GRRPPDAVDAAMATSGLAVVLSGMTVIA MLBr_02617|M.leprae_Br4923 VDYSLFILMRFREELRS-----GRQPQEAVDAAMATSGLAVVLSGMTVIA MAB_4529|M.abscessus_ATCC_1997 VDYSLFILMRYREELNS-----GKNRQEAIAGAMATSGLTVTFSGLTVIA .:*:*::: *:*:** *: :: :. .: *. **: Mflv_0224|M.gilvum_PYR-GCK ALLTLLFASSPSTRSLGVQAAAGLVVAAVFVLLVLPPALAVFGRKLFWP- Mvan_0683|M.vanbaalenii_PYR-1 ALLTLLLASSPSTRSLGVQAASGLVIAAVFVLLVLPPALGVFGRKLFWP- MSMEG_0763|M.smegmatis_MC2_155 ALLTLLFATAPSNRSLGVQAASGLVVAAVFVLIVLPPLLALCGKRLFWP- TH_3700|M.thermoresistible__bu ALLTLLFGVVPSTRSLGLQAASGLVVAAVFVLLVLPPLLALFGRRLFWP- MMAR_1673|M.marinum_M ALLTLVFAATPSTRSLGALAACGLVVAAVSVLVVLPPLLALCGRRLFWP- MUL_1909|M.ulcerans_Agy99 ALLTLVFAATPSNRSLGALAACGVVVAAVSVLVVLPPLLALCGRRLFWP- MAV_3895|M.avium_104 ALLTLLLAATPSTRSLGALAACGLVIAAVSVLVVLPPLLAVCGRRLFWP- Mb0208c|M.bovis_AF2122/97 SLTGIYLINTPALRSMATGAILAVAVAMLTSATLTPAVLATFARAAAKRS Rv0202c|M.tuberculosis_H37Rv SLTGIYLINTPALRSMATGAILAVAVAMLTSATLTPAVLATFARAAAKRS MLBr_02617|M.leprae_Br4923 SLTGIYLINTAALKSMATGAILAVAIAMLASITLTPAALATFGRAAVKRS MAB_4529|M.abscessus_ATCC_1997 ALAGIYLIGTPALASMASGAIIVVAIAVLTSTTLMPALLAIFGKAAANQS :* : : .: *:. * :.:* : : *. *. .: Mflv_0224|M.gilvum_PYR-GCK -FIPAVGDQPLTDSGVWHRIAAAVARRPARVAIVSIGGLALLCTGILGTP Mvan_0683|M.vanbaalenii_PYR-1 -FIPQVGAKPLTDSGVWHRVAAAVARRPARVAIVSIGGLALLCTGLLGTP MSMEG_0763|M.smegmatis_MC2_155 -FIPKVGATALTESGVWHRIADTVARRPARVVVVSVAGLALLCTALLTTP TH_3700|M.thermoresistible__bu -FVPQPGAEPLTDSGLWRRIADWVADRPGPVAAATLAVLAVMCTGLLGTP MMAR_1673|M.marinum_M -FIPRAEDTTALDSGFWHAVAQRVARRPAPVALVTVALLIGLATGLLGTR MUL_1909|M.ulcerans_Agy99 -FIPRAEDTTALDSGFWHAVAQRVARRPAPVALVTVALLIGLATGLLGTR MAV_3895|M.avium_104 -FIP--VDRPATESGAWRRVAEWVAGRPALVAVAAVAVLAALGGGLWGTR Mb0208c|M.bovis_AF2122/97 ALVHWSRRPASTQSWFWSRWVGWVMRRPWITALAASTVLLVMAAPATLMV Rv0202c|M.tuberculosis_H37Rv ALVHWSRRPASTQSWFWSRWVGWVMRRPWITALAASTVLLVMAAPATLMV MLBr_02617|M.leprae_Br4923 VLMHWSQRSECTQSLFWTRWVGWVMHRPWISASAASTILIIMATPVTSMM MAB_4529|M.abscessus_ATCC_1997 RFLRVSPLRKHSIP-FWRKWTQQVMRRPWLSALGASIFLLALAAPSLQMH :: . * . * ** . : * : Mflv_0224|M.gilvum_PYR-GCK VGLSQTEQFRVEAESVRGFDTLAAHFPSGLTDPTRVIATSDRS------- Mvan_0683|M.vanbaalenii_PYR-1 VGLSQTEQFRVQAESVSGFETLAAHFPSGLTAPARVIASTDRA------- MSMEG_0763|M.smegmatis_MC2_155 IGLTQTEQFRVQAESVSGFETVSAHFPSGLTDPTRVIASTDKA------- TH_3700|M.thermoresistible__bu IGLSQTEQFRVQAESVTGYETLAAHFPRGITDPTQVLASTERA------- MMAR_1673|M.marinum_M IGLSQTEQFRVKADSVSGYDVVAQHFPAGLVNPTLVVAPSAQA------- MUL_1909|M.ulcerans_Agy99 IGLSQTEQFRVKADSVSGYDVVAQHFPAGLVNPTLVVAPSAQA------- MAV_3895|M.avium_104 IGLSQTEQFRVRADSVAGYHVLAQHFPAGLANPTLVVADTGHA------- Mb0208c|M.bovis_AF2122/97 LGNSLLRQFDSSHEIRTGAAAAAQALGPGALGPVQVLVRFDAG---GASA Rv0202c|M.tuberculosis_H37Rv LGNSLLRQFDSSHEIRTGAAAAAQALGPGALGPVQVLVRFDAG---GASA MLBr_02617|M.leprae_Br4923 LGNSLLRQFNSSHEIRAGVAAAAQALGPGALGPVQVLITFPDDPNTQASS MAB_4529|M.abscessus_ATCC_1997 VSNSMLRQFDSSHEIRRGIDAAAVAMGPGALGPVQVLLTFKDS-----PA :. : .** : * . : : * *. *: Mflv_0224|M.gilvum_PYR-GCK -------AEVQRAITATPGVVSAFPAGAE---ADGRSQWSVVLDAEPASD Mvan_0683|M.vanbaalenii_PYR-1 -------AEVQRAITATPGVVSAIPAGSG---PGGVSQWSVVLEAAPASD MSMEG_0763|M.smegmatis_MC2_155 -------AAVQRAITDTEGVVSASPAGES---PTGLTQWSVVLGADPASD TH_3700|M.thermoresistible__bu -------NEVELAITETPGVVSAAESGRS---GTGLTQWSVVLDAEPASA MMAR_1673|M.marinum_M -------TQVRQAIGATPGVVSVTESGRSGKFGAGLTKWSVVIDAPPSSE MUL_1909|M.ulcerans_Agy99 -------TQVRQAIGATPGVVSVTESGRSGKFGAGLTKWSVVIDAPPSSE MAV_3895|M.avium_104 -------AAVHQAMAATPGVVSATESGRS---ASGLTQWSVVIDAPPSSV Mb0208c|M.bovis_AF2122/97 PEHSQTIAAIRHRIAQAPNVVSVAPPRFAD--DNGSALLSAVLSVDPEDL Rv0202c|M.tuberculosis_H37Rv PEHSQTIAAIRHRIAQAPNVVSVAPPRFAD--DNGSALLSAVLSVDPEDL MLBr_02617|M.leprae_Br4923 PKHRQTIGAIRNRMLQAKNVMSVAPPQFAD--NNCSALLGAVLSVDPEDL MAB_4529|M.abscessus_ATCC_1997 HAHAQALETAKETIAQAPNIARVSDVSFST--DGHDALISAVLSVDPEAN . : : .: . : ..*: . * Mflv_0224|M.gilvum_PYR-GCK EAFDTIDALRESVHRADP----DALVGGSDATARDAAAAAGHDRAVVIPA Mvan_0683|M.vanbaalenii_PYR-1 AAFEAVDALRDSVHRVDP----DALVGGSDATARDAASAAAHDRAVVIPA MSMEG_0763|M.smegmatis_MC2_155 EAFETIDALRGSVQHADA----DAVVGGSDAQARDAAAAAQRDRAVVIPA TH_3700|M.thermoresistible__bu EAFETVDALRDSVRKADQ----SALVGGSDAQARDASAASTRDRLVLIPA MMAR_1673|M.marinum_M RAFTTIAALRHSASQASP----SALVGGPDAQALDVRDAAEHDRALLIPA MUL_1909|M.ulcerans_Agy99 RAFTTIAALRHSASQASP----SALVGGPDAQALDVRDAAEHDRALLIPA MAV_3895|M.avium_104 RAFDIVAALRDSTRAADS----GALVGGADAAALDVRDAATHDRVLLIPA Mb0208c|M.bovis_AF2122/97 GARDTITWMRTQLPRVAG--AAQVDVGGPTALIKDFDDRVSATQPLVLVF Rv0202c|M.tuberculosis_H37Rv GARDTITWMRTQLPRVAG--AAQVDVGGPTALIKDFDDRVSATQPLVLVF MLBr_02617|M.leprae_Br4923 GARETVDWMRTELPKVPG--AAHVNVGGPTALINDFDDRVAKTEPLMLVF MAB_4529|M.abscessus_ATCC_1997 AARDTVSWLRANVPDALENSGADINVGGPTALLFDYDTRVEHSLLGVFAF * : :* . . ***. * * :: Mflv_0224|M.gilvum_PYR-GCK ILVVVLIVLYVLLRSALAPLVLVGVTVLSSVAALG----LGGWASVHLFG Mvan_0683|M.vanbaalenii_PYR-1 ILVVVLLVLYLLLRSALAPLVLVGVTVLSALAALG----LGGWASVHVFG MSMEG_0763|M.smegmatis_MC2_155 ILVVVLAVLYILLRSAFAPLLLVGVTVLSSLAALG----LGGWASVHIFG TH_3700|M.thermoresistible__bu ILVVVLAVLYVLLRAALAPLVLVAVSLLSSLAALG----LGGWISVHVFG MMAR_1673|M.marinum_M ILAVILVVLYALLRSALAPLILLAATILGALAALG----LGGWASIHVFG MUL_1909|M.ulcerans_Agy99 ILAVILVVLYALLRSALAPLILLAATILGALAALG----LGGWASIHVFG MAV_3895|M.avium_104 ILAVILIVLAVLLRSVMAPPVLLVATMLGALGALG----LGGWVSLHLFG Mb0208c|M.bovis_AF2122/97 VAVIAFLMLLISIRSVFLAFKGVLMTLLSVAAAYGSLVMVFQWGWARGLG Rv0202c|M.tuberculosis_H37Rv VAVIAFLMLLISIRSVFLAFKGVLMTLLSVAAAYGSLVMVFQWGWARGLG MLBr_02617|M.leprae_Br4923 VALIAFVMLLISIRSVFLAFKGVLMTLLSVAAAYGSLVMVFQWGWLENLG MAB_4529|M.abscessus_ATCC_1997 VCVLAFVMLLATLRSPVLALKGVVMTVLSVAAAYGSLVIVFQWGWLEFLG : : : :* :*: . . : ::*. .* * : * . :* Mflv_0224|M.gilvum_PYR-GCK F---PALDNTAPLFAFLFLVALGVDYTIFLVTRAREETPGHG-TRDGIVR Mvan_0683|M.vanbaalenii_PYR-1 F---PALDYTAPLFAFLFLVALGVDYTIFLVTRAREETPEHG-TRDGIVR MSMEG_0763|M.smegmatis_MC2_155 F---PALDNGTPLFAFLFLVALGVDYTIFLVTRAREETPQYG-NREGIVR TH_3700|M.thermoresistible__bu F---PALDFATPLFALLFLVALGVDYTIFLVTRAREETVGHG-TRGGIVR MMAR_1673|M.marinum_M F---PALDNSTPLFAFLFLAALGVDYTIFLVTRAREESARNG-ARAGMVR MUL_1909|M.ulcerans_Agy99 F---PALDNSTPLFAFLFLAALGVDYTIFLVTRAREESARNG-ARAGMVR MAV_3895|M.avium_104 F---PALDYTTPLFAFLFLAALGVDYTIFLVARAREEAARHG-TRQGMVE Mb0208c|M.bovis_AF2122/97 FPALHSIDSTVPPLVLAMTFGLSMDYEIFLLTRIRERFLQTGQTRDAVAY Rv0202c|M.tuberculosis_H37Rv FPALHSIDSTVPPLVLAMTFGLSMDYEIFLLTRIRERFLQTGQTRDAVAY MLBr_02617|M.leprae_Br4923 FTHINSIDSTVPPLVLAMTFGLSMDYEIFLLTRIRERFLQTGHTRDAVAY MAB_4529|M.abscessus_ATCC_1997 FHKAN-IDSSIPPLALALTFGLTMDYEIFLLARVRERYLRTGDCGDAVSY * :* * :.: : .* :** ***::* **. * .: Mflv_0224|M.gilvum_PYR-GCK AVSATGAVISSAGIVLAAVFCVLGVLPLIVLTQVGIIVGLGILLDTFLVR Mvan_0683|M.vanbaalenii_PYR-1 AVSATGAVITSAGIVLAAVFCVLGVLPLIVLTQVGIIVGLGILLDTFVVR MSMEG_0763|M.smegmatis_MC2_155 AVSATGAVITSAGVVLAAVFCVLGVLPLIVLTQLGIIVGLGILLDTFLVR TH_3700|M.thermoresistible__bu AVSATGAVITSAGIVLAAVFCVLGVLPLIVLTQLGIIVGLGILLDTFVVR MMAR_1673|M.marinum_M AVSATGGVITSAGIVLAAVFCVLAVLPLIVLTQLGIIVGLGILLDTFVVR MUL_1909|M.ulcerans_Agy99 AVSATGGVITSAGIVLAAVFCVLAVLPLIVLTQLGIIVGLGILLDTFVVR MAV_3895|M.avium_104 AVAATGGVITSAGIVLAAVFCVLAVLPLMVLTQLGIIVGLGILLDTFVVR Mb0208c|M.bovis_AF2122/97 GVRTSARTITSAALIMIAVFCGFAFAGMPLVAEIGVACAVAIAVDATVVR Rv0202c|M.tuberculosis_H37Rv GVRTSARTITSAALIMIAVFCGFAFAGMPLVAEIGVACAVAIAVDATVVR MLBr_02617|M.leprae_Br4923 GVSTSARTITSAALIMIAVFVGFAFAGMPLVAEIGVACAVAIAVDVTAVR MAB_4529|M.abscessus_ATCC_1997 GVRTSARTITSAALIMIAVFIGFAFVGMPLVAQLGVACAVAIAVDATVVR .* ::. .*:**.::: *** :.. : :::::*: .:.* :*. ** Mflv_0224|M.gilvum_PYR-GCK TVIIPALFTLIGPKIWWPALRQETRSDA---------------------- Mvan_0683|M.vanbaalenii_PYR-1 TVIIPALFTLIGPRIWWPALREDGPSRGR--------------------- MSMEG_0763|M.smegmatis_MC2_155 TVIIPALFTWIGPKIWWPGLRAEP-------------------------- TH_3700|M.thermoresistible__bu TVVVPALFTLIGPRMWWPALRAAE-------------------------- MMAR_1673|M.marinum_M TLVIPALFTLIGDRIWWPSDPKTTAHQPDLAYSHADGGSE---------- MUL_1909|M.ulcerans_Agy99 TLVIPALFTLIGDRIWWPSDPKTTAHQPDLAYSHADGGSE---------- MAV_3895|M.avium_104 TLVIPALFTLVGDRIWWPNNP--SRHERSTP------------------- Mb0208c|M.bovis_AF2122/97 LVLVPALMAMFDRWNWWLPRWLAHILPSVDFDRPLPKVDLG--DVVVIPD Rv0202c|M.tuberculosis_H37Rv LVLVPALMAMFDRWNWWLPRWLAHILPSVDFDRPLPKVDLG--DVVVIPD MLBr_02617|M.leprae_Br4923 LVLVPTLMAMFAQWNWWLPRWLSRALPAVDFDKPFPPVDLN--EIVVLPA MAB_4529|M.abscessus_ATCC_1997 LVLVPALMAMFDKRNWWLPGWLDHVLPTVDFETPCVDELPGPHSESALRL :::*:*:: . ** Mflv_0224|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0683|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0763|M.smegmatis_MC2_155 -------------------------------------------------- TH_3700|M.thermoresistible__bu -------------------------------------------------- MMAR_1673|M.marinum_M -------------------------------------------------- MUL_1909|M.ulcerans_Agy99 -------------------------------------------------- MAV_3895|M.avium_104 -------------------------------------------------- Mb0208c|M.bovis_AF2122/97 DFAAAIPPSADVRMVLKSAAKLKRLAP-DAICVTDPLAFTGCGCDGKALD Rv0202c|M.tuberculosis_H37Rv DFAAAIPPSADVRMVLKSAAKLKRLAP-DAICVTDPLAFTGCGCDGKALD MLBr_02617|M.leprae_Br4923 DISATKVPCGDLRMVLKLAAKLKNLAP-DAICVADPLAFTGCGRNNKRSD MAB_4529|M.abscessus_ATCC_1997 QGSGFEEPRIDYHAIAVSAARLKRLADGGTITAPDTQAV----------- Mflv_0224|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0683|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0763|M.smegmatis_MC2_155 -------------------------------------------------- TH_3700|M.thermoresistible__bu -------------------------------------------------- MMAR_1673|M.marinum_M -------------------------------------------------- MUL_1909|M.ulcerans_Agy99 -------------------------------------------------- MAV_3895|M.avium_104 -------------------------------------------------- Mb0208c|M.bovis_AF2122/97 QVQ----------------------------------------------- Rv0202c|M.tuberculosis_H37Rv QVQ----------------------------------------------- MLBr_02617|M.leprae_Br4923 RVLPGAATQESEEDPAMGKASDSTAALTAAQVGPVTRTNGHWTARNLVIG MAB_4529|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_0224|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0683|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0763|M.smegmatis_MC2_155 -------------------------------------------------- TH_3700|M.thermoresistible__bu -------------------------------------------------- MMAR_1673|M.marinum_M -------------------------------------------------- MUL_1909|M.ulcerans_Agy99 -------------------------------------------------- MAV_3895|M.avium_104 -------------------------------------------------- Mb0208c|M.bovis_AF2122/97 LAYRNGIARAISWGQRPVHPVTVWRKRLAVALDALQTTTWECGGVQTHRA Rv0202c|M.tuberculosis_H37Rv LAYRNGIARAISWGQRPVHPVTVWRKRLAVALDALQTTTWECGGVQTHRA MLBr_02617|M.leprae_Br4923 LTHRNSITRVMPWSDRPVHPFTLWRSRFSVAIDALEAHIAVQADAPDQ-- MAB_4529|M.abscessus_ATCC_1997 LADR-------------------WRDNLTVALEALQTSKNGTDTDIVEMP Mflv_0224|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0683|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0763|M.smegmatis_MC2_155 -------------------------------------------------- TH_3700|M.thermoresistible__bu -------------------------------------------------- MMAR_1673|M.marinum_M -------------------------------------------------- MUL_1909|M.ulcerans_Agy99 -------------------------------------------------- MAV_3895|M.avium_104 -------------------------------------------------- Mb0208c|M.bovis_AF2122/97 GPGYRRRSPVETTNVALPTGDRLQIPTGAETLRFKGYLIMSRNSSHDYAD Rv0202c|M.tuberculosis_H37Rv GPGYRRRSPVETTNVALPTGDRLQIPTGAETLRFKGYLIMSRNSSHDYAD MLBr_02617|M.leprae_Br4923 -PNYQRCSPVETAHVQLPTGDRLLIPTGAETLRLVSYLIMCRNSIRDYAE MAB_4529|M.abscessus_ATCC_1997 GPLSR-VTPVEITQVKLPTGQKCVVPTDAEALRMQGLLLMRRNAERDYTE Mflv_0224|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0683|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0763|M.smegmatis_MC2_155 -------------------------------------------------- TH_3700|M.thermoresistible__bu -------------------------------------------------- MMAR_1673|M.marinum_M -------------------------------------------------- MUL_1909|M.ulcerans_Agy99 -------------------------------------------------- MAV_3895|M.avium_104 -------------------------------------------------- Mb0208c|M.bovis_AF2122/97 FADLVDTMAPETAAAVLAGMDRYYSCQAPGRQWMATQLVGRLADPQPSDL Rv0202c|M.tuberculosis_H37Rv FADLVDTMAPETAAAVLAGMDRYYSCQAPGRQWMATQLVGRLADPQPSDL MLBr_02617|M.leprae_Br4923 LADMVDAIEPETAAVVLTELDRYYSCQLPMRQWMATQLVRRLSDPHPVDL MAB_4529|M.abscessus_ATCC_1997 FARLASAMEPRMAAKVLAGIDQHYCVQSNQR-WVSSQLVRRLADPKP--- Mflv_0224|M.gilvum_PYR-GCK --------------------------------- Mvan_0683|M.vanbaalenii_PYR-1 --------------------------------- MSMEG_0763|M.smegmatis_MC2_155 --------------------------------- TH_3700|M.thermoresistible__bu --------------------------------- MMAR_1673|M.marinum_M --------------------------------- MUL_1909|M.ulcerans_Agy99 --------------------------------- MAV_3895|M.avium_104 --------------------------------- Mb0208c|M.bovis_AF2122/97 GD-QSPGADAQAKWEEVRRRCLSVAVAMLEEAR Rv0202c|M.tuberculosis_H37Rv GD-QSPGADAQAKWEEVRRRCLSVAVAMLEEAR MLBr_02617|M.leprae_Br4923 TEDQWSDPDNKAEWQDVRQRCLSVAVAMLEEAR MAB_4529|M.abscessus_ATCC_1997 -------GDGAMECPTVRRQCLSVAVAMLEDAR