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M. thermoresistible (build 8) TH_3698 (-)

annotation: hydroxyneurosporene-O-methyltransferase
coordinates: 2912762 - 2913886
length: 375

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_3698 - - 100% (375) hydroxyneurosporene-O-methyltransferase
M. thermoresistible (build 8) TH_3167 - 8e-72 39.83% (354) PUTATIVE hydroxyneurosporene-O-methyltransferase

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0582 - 2e-17 23.22% (323) methyltransferase/methylase
M. gilvum PYR-GCK Mflv_3940 - 2e-79 42.37% (354) O-methyltransferase family protein
M. tuberculosis H37Rv Rv0567 - 4e-18 23.53% (323) methyltransferase/methylase
M. leprae Br4923 - - - - -
M. abscessus ATCC 19977 - - - - -
M. marinum M MMAR_0934 - 3e-17 22.36% (322) methyltransferase/methylase
M. avium 104 - - - - -
M. smegmatis MC2 155 MSMEG_0367 - 3e-81 41.97% (355) O-demethylpuromycin-O-methyltransferase
M. ulcerans Agy99 MUL_0686 - 8e-17 22.05% (322) methyltransferase/methylase
M. vanbaalenii PYR-1 Mvan_2460 - 6e-86 47.04% (355) O-methyltransferase family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3940|M.gilvum_PYR-GCK          MTHTSTPRGSAARSAPNRVPPVRLIRAVDRLRAGLQRLHRSTAPGNVALM
Mvan_2460|M.vanbaalenii_PYR-1       -----------MRTMLMTPPPVVLA-AVGRFRGLLDRLHTLTAPSHIAVL
MSMEG_0367|M.smegmatis_MC2_155      ------------------MPPARLVRAVERARHHVRRLWLRSVPPEAAML
TH_3698|M.thermoresistible__bu      -MVSRHTFARTTTTHSPTIPPPALVRAVETVRTGLQRVRARMAPPFAGVL
Mb0582|M.bovis_AF2122/97            ----------------------------------------MELS-PDRIM
Rv0567|M.tuberculosis_H37Rv         ----------------------------------------MELS-PDRIM
MMAR_0934|M.marinum_M               ----------------------------------------MDQSSPDRIM
MUL_0686|M.ulcerans_Agy99           ----------------------------------------MDQSRPDRIM
                                                                               .    ::

Mflv_3940|M.gilvum_PYR-GCK          ELATGAWTTQVLYVAATLGIPDELADGPAHAADVATRVGADAGAVYRLMR
Mvan_2460|M.vanbaalenii_PYR-1       ELSLGSWFTAALYATVRLGIADALADGPLRADDVARKVGADPEATYRLMR
MSMEG_0367|M.smegmatis_MC2_155      ELLLGAWLAQGITAAAQLGVADALSGGPLRADELARRVGADADALDRLMR
TH_3698|M.thermoresistible__bu      DLAMGYAVSHAVQAAARLAIADVFDDGPLSVERIAERIDADAHAVRRLLR
Mb0582|M.bovis_AF2122/97            AIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLD
Rv0567|M.tuberculosis_H37Rv         AIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAIDFLD
MMAR_0934|M.marinum_M               AIGAGYGPSKVLLTAVGLGLFTELGDRAMTAQAIAELLGLVPRPATDFLD
MUL_0686|M.ulcerans_Agy99           AIGAGYGPSKVLLTAVGLGLFTELGDRAMTAQALAELLGLVPRPATDFLD
                                     :  *   :  : .:. *.:   : . .  .  :*  :.    .   :: 

Mflv_3940|M.gilvum_PYR-GCK          AMVSRGALREERDG---RFALTPVGDALRTDSEGSLRDMVLFIGHPARWA
Mvan_2460|M.vanbaalenii_PYR-1       ALASRSVLKLRRDG---RFALTRLGHALRVDHPESMAPLIAFVGSRQHWE
MSMEG_0367|M.smegmatis_MC2_155      ALVGEGVFRRTRDG---RYALNPLGDTLRTDAQVSMAGMAKFVGAAQHRE
TH_3698|M.thermoresistible__bu      VLASHQIFRERRDG---RFEMTPMSHALRSDAPVSIRPLLMMISHPFYTE
Mb0582|M.bovis_AF2122/97            ALVSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYR
Rv0567|M.tuberculosis_H37Rv         ALVSLDLLARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLKIWNERNYR
MMAR_0934|M.marinum_M               ALVSLDLLARDGDGPDARYRNTAETARYLDEASPEYQGGLLKIWDQRNYR
MUL_0686|M.ulcerans_Agy99           ALVSLDLLARDGDGPDARYRNTAETARYLDEASPEYQGGLLKIWDQRNYR
                                    .:..   :    **   ::  .        :           :       

Mflv_3940|M.gilvum_PYR-GCK          DWGSLEYSVRTGEPAADMLR-GMPFFDYLDTDPEFATVFNNAMTAASGLS
Mvan_2460|M.vanbaalenii_PYR-1       HWGELLYSVQTGRTAVEKLR-GSEFFEYLDTDPAFAKVFNESMTGGSRAV
MSMEG_0367|M.smegmatis_MC2_155      HWSHLADAVRTGESAIRTLR-GMEPFDYIASQPELGTIFNDAMTSMSELA
TH_3698|M.thermoresistible__bu      HFARLPDVVRTGRTSVESTY-GAGLFDCLEQDPDAAAVFNDAMTCVTAMA
Mb0582|M.bovis_AF2122/97            FWADLTEALKTGKAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRN
Rv0567|M.tuberculosis_H37Rv         FWADLTEALKTGKAQSEVKQTGRPFFEALYADPRRLEAFMAAMDAASRRN
MMAR_0934|M.marinum_M               FWADLTDALQTGKPQNEIKQTGRPFFETVYADPRRLEVFLGAMDSASRRN
MUL_0686|M.ulcerans_Agy99           FWADLTDALQTGKPQNEIKQTGRPFFETVYADPRRLEVFLGAMDSASRRN
                                     :. *   ::**..       *   *: :  :*     *  :*   :   

Mflv_3940|M.gilvum_PYR-GCK          DDVALQACDFTGARLVVDVGGGHGAVLATILRSAAGARGILFDLPAVVAG
Mvan_2460|M.vanbaalenii_PYR-1       IENAIPAYDFSDRRLIVDVGGGEGGLLAAILNRTPTARGVLFDRPSVVAG
MSMEG_0367|M.smegmatis_MC2_155      ITPLIAAYDFTRFGTIADVGGGHGRLLSAILGSAPQAKGVLYDLPNVVEG
TH_3698|M.thermoresistible__bu      VPPVLAAYDFTDAETIVDVGGGAGQLLAAVLNAAPQARGVLFEQSSLKDH
Mb0582|M.bovis_AF2122/97            IELLAKRFPFERYRRLCDVGCADGLLSRIVAAAHPHLQCVSLDLPAVTEI
Rv0567|M.tuberculosis_H37Rv         IELLAKRFPFERYRRLCDVGCADGLLSRIVAAAHPHLQCVSFDLPAVTEI
MMAR_0934|M.marinum_M               CELLVKRFPFQRYGSLCDVGGANGLLSRTAAAAHPHLQCISFDLPAVTDI
MUL_0686|M.ulcerans_Agy99           CELLVKRFPFQRYGSLCDVGGANGLLSRTAAAAHPHLQCISFDLPAVTDI
                                             *     : *** . * :        .  : :  : . :   

Mflv_3940|M.gilvum_PYR-GCK          AAPLLADAGVADRCTVSGGSFLESVPAGGDVYVMKNIVHDWDDTDAATIL
Mvan_2460|M.vanbaalenii_PYR-1       ADSVLGPAGVAARCRTEGGSFFEAVPAGGDAYVMKAIIHDWGDDQSLSIL
MSMEG_0367|M.smegmatis_MC2_155      APEMLARHGVADRVQVIPGSFFDEVPDGADLYVMKNIIHDWADAPAAEIL
TH_3698|M.thermoresistible__bu      AQRVFESAGVADRATIETGSFFEAVPEGGDIYLLKHVVHDWDDRQAAAIL
Mb0582|M.bovis_AF2122/97            ARRKLTAEGLGERVQACAGDFLADPLPAADVITMGQILHDWNLDRKQQLV
Rv0567|M.tuberculosis_H37Rv         ARRKLTAEGLGERVQACAGDFLADPLPAADVITMGQILHDWNLDRKQQLV
MMAR_0934|M.marinum_M               TRRKLSEQGLGDRVRAVSGDFFADPLPSADVITMGQILHDWNLDGKQRLI
MUL_0686|M.ulcerans_Agy99           TRRKLSEQGLGDRVRAVSGDFFADPLPSADVITMGQILHDWNLDGKQRLI
                                    :   :   *:. *     *.*:     ..*   :  ::***       ::

Mflv_3940|M.gilvum_PYR-GCK          RNVRTAIAEGGKLVLLEMVLPERASS-FIGHMLDLEMLLMLR-GKERTRA
Mvan_2460|M.vanbaalenii_PYR-1       RNVRTAIADDGRLLLFEMVLPERAPA-HLGFMVDLEMLVTAG-GRERTAS
MSMEG_0367|M.smegmatis_MC2_155      RNVRAAARTGATLLLVEGVIPDHDRA-FPLKWVDMEMLIGNA-ARERTEA
TH_3698|M.thermoresistible__bu      ATVRESMSPNARLLLAETVIPPGNRP-HFGKLLDLDMLVFAG-GRERTAP
Mb0582|M.bovis_AF2122/97            AKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGDAFDYSAA
Rv0567|M.tuberculosis_H37Rv         AKAYEALSKEGAFIVIETLIDDARRENTTGLMMSLNMLIEFGDAFDYSAA
MMAR_0934|M.marinum_M               AKAYEALPEGGAFIAIETLIDDARRKNTAGLMMSLNMLIEFGDAFDYTGA
MUL_0686|M.ulcerans_Agy99           AKAYEALPEGGAFTAIETLIDDARRKNTAGLMMSLNMLIEFGDAFDYTGA
                                     ..  :    . :   * ::            :.::**:    . : : .

Mflv_3940|M.gilvum_PYR-GCK          QYSELLEAAGFQLTRVIPTVSPISVIEARAV
Mvan_2460|M.vanbaalenii_PYR-1       QYAKLLADSGFRMTRVIPTASPLSIVEAVPA
MSMEG_0367|M.smegmatis_MC2_155      QYRKLYTEAGFRLTRVVPTACPYSLIEGVAI
TH_3698|M.thermoresistible__bu      EFTDLLTGSGFTPPRIIPTAIHLSLLEAVPN
Mb0582|M.bovis_AF2122/97            DFRGWCGEAGFRSFEVIPLAGGSSAAVAYK-
Rv0567|M.tuberculosis_H37Rv         DFRGWCGEAGFRSFEVIPLAGGSSAAVAYK-
MMAR_0934|M.marinum_M               DFRKWCGAAGFRSFEVIALAAGSSAAVAYK-
MUL_0686|M.ulcerans_Agy99           DFRKWCGAAGFRSFEVIALAAGSSAAVAYK-
                                    ::      :**   .::. .   *   .

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_3698	-	-	100% (375)	hydroxyneurosporene-O-methyltransferase
M. thermoresistible (build 8)	TH_3167	-	8e-72	39.83% (354)	PUTATIVE hydroxyneurosporene-O-methyltransferase