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M. thermoresistible (build 8) TH_3167 (-)

annotation: hydroxyneurosporene-O-methyltransferase
coordinates: 939492 - 940667
length: 392

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3167--100% (392)hydroxyneurosporene-O-methyltransferase
M. thermoresistible (build 8)TH_3698-8e-7239.83% (354) PUTATIVE hydroxyneurosporene-O-methyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0582-1e-2326.88% (320) methyltransferase/methylase
M. gilvum PYR-GCKMflv_3940-5e-8745.80% (369) O-methyltransferase family protein
M. tuberculosis H37RvRv0567-2e-2427.19% (320) methyltransferase/methylase
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_0934-4e-2828.78% (337) methyltransferase/methylase
M. avium 104-----
M. smegmatis MC2 155MSMEG_0367-1e-11057.02% (356) O-demethylpuromycin-O-methyltransferase
M. ulcerans Agy99MUL_0686-5e-2829.06% (320) methyltransferase/methylase
M. vanbaalenii PYR-1Mvan_2460-1e-8750.69% (361) O-methyltransferase family protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_3167|M.thermoresistible__bu      LQTEYVEVTRIAPVRSRRYDPITRSGGVVMSARVRVPPARIARTADAARH
MSMEG_0367|M.smegmatis_MC2_155      -----------------------------------MPPARLVRAVERARH
Mflv_3940|M.gilvum_PYR-GCK          -----------------MTHTSTPRGSAARSAPNRVPPVRLIRAVDRLRA
Mvan_2460|M.vanbaalenii_PYR-1       ----------------------------MRTMLMTPPPVVLA-AVGRFRG
Mb0582|M.bovis_AF2122/97            --------------------------------------------------
Rv0567|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_0934|M.marinum_M               --------------------------------------------------
MUL_0686|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

TH_3167|M.thermoresistible__bu      YLLRLQQKLTAPQAVMLEMILAGWTSQALTTAADLGVADALADGPLAIGD
MSMEG_0367|M.smegmatis_MC2_155      HVRRLWLRSVPPEAAMLELLLGAWLAQGITAAAQLGVADALSGGPLRADE
Mflv_3940|M.gilvum_PYR-GCK          GLQRLHRSTAPGNVALMELATGAWTTQVLYVAATLGIPDELADGPAHAAD
Mvan_2460|M.vanbaalenii_PYR-1       LLDRLHTLTAPSHIAVLELSLGSWFTAALYATVRLGIADALADGPLRADD
Mb0582|M.bovis_AF2122/97            -------MELS-PDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEA
Rv0567|M.tuberculosis_H37Rv         -------MELS-PDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEA
MMAR_0934|M.marinum_M               -------MDQSSPDRIMAIGAGYGPSKVLLTAVGLGLFTELGDRAMTAQA
MUL_0686|M.ulcerans_Agy99           -------MDQSRPDRIMAIGAGYGPSKVLLTAVGLGLFTELGDRAMTAQA
                                              .    :: :  .   :  : .:. **:   *.. .     

TH_3167|M.thermoresistible__bu      LARKVDADPERLARLMCALTSRGVFRQRRDG---RYALNALATTLRSDAS
MSMEG_0367|M.smegmatis_MC2_155      LARRVGADADALDRLMRALVGEGVFRRTRDG---RYALNPLGDTLRTDAQ
Mflv_3940|M.gilvum_PYR-GCK          VATRVGADAGAVYRLMRAMVSRGALREERDG---RFALTPVGDALRTDSE
Mvan_2460|M.vanbaalenii_PYR-1       VARKVGADPEATYRLMRALASRSVLKLRRDG---RFALTRLGHALRVDHP
Mb0582|M.bovis_AF2122/97            IADRLGLLKRPAIDFLDALVSLDLLARDGDGPGSHYRNTPETAHFLDEAR
Rv0567|M.tuberculosis_H37Rv         IADRLGLLKRPAIDFLDALVSLDLLARDGDGPGSHYRNTPETAHFLDEAR
MMAR_0934|M.marinum_M               IAELLGLVPRPATDFLDALVSLDLLARDGDGPDARYRNTAETARYLDEAS
MUL_0686|M.ulcerans_Agy99           LAELLGLVPRPATDFLDALVSLDLLARDGDGPDARYRNTAETARYLDEAS
                                    :*  :.        :: *:.. . :    **   ::  .        :  

TH_3167|M.thermoresistible__bu      ASLAGAARFYGSRLHREHWSMLTDSVRTGKPGVPTLR-GMDWWQFSAANP
MSMEG_0367|M.smegmatis_MC2_155      VSMAGMAKFVGAAQHREHWSHLADAVRTGESAIRTLR-GMEPFDYIASQP
Mflv_3940|M.gilvum_PYR-GCK          GSLRDMVLFIGHPARWADWGSLEYSVRTGEPAADMLR-GMPFFDYLDTDP
Mvan_2460|M.vanbaalenii_PYR-1       ESMAPLIAFVGSRQHWEHWGELLYSVQTGRTAVEKLR-GSEFFEYLDTDP
Mb0582|M.bovis_AF2122/97            PTYAGGLLKIWNERNYRFWADLTEALKTGKAQSEVKQTGRPFFEALYADP
Rv0567|M.tuberculosis_H37Rv         PTYAGGLLKIWNERNYRFWADLTEALKTGKAQSEVKQTGRPFFEALYADP
MMAR_0934|M.marinum_M               PEYQGGLLKIWDQRNYRFWADLTDALQTGKPQNEIKQTGRPFFETVYADP
MUL_0686|M.ulcerans_Agy99           PEYQGGLLKIWDQRNYRFWADLTDALQTGKPQNEIKQTGRPFFETVYADP
                                                  .   *. *  :::**..     : *   ::   ::*

TH_3167|M.thermoresistible__bu      EFGDLFNGAMTSISELSAPVVAAAYDFSPFPTIVDVGGGHGRLLSAILAA
MSMEG_0367|M.smegmatis_MC2_155      ELGTIFNDAMTSMSELAITPLIAAYDFTRFGTIADVGGGHGRLLSAILGS
Mflv_3940|M.gilvum_PYR-GCK          EFATVFNNAMTAASGLSDDVALQACDFTGARLVVDVGGGHGAVLATILRS
Mvan_2460|M.vanbaalenii_PYR-1       AFAKVFNESMTGGSRAVIENAIPAYDFSDRRLIVDVGGGEGGLLAAILNR
Mb0582|M.bovis_AF2122/97            RRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADGLLSRIVAAA
Rv0567|M.tuberculosis_H37Rv         RRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADGLLSRIVAAA
MMAR_0934|M.marinum_M               RRLEVFLGAMDSASRRNCELLVKRFPFQRYGSLCDVGGANGLLSRTAAAA
MUL_0686|M.ulcerans_Agy99           RRLEVFLGAMDSASRRNCELLVKRFPFQRYGSLCDVGGANGLLSRTAAAA
                                         *  :* . *            *     : *** ..* :       

TH_3167|M.thermoresistible__bu      TPTARGVLFDLPDVVADAPALLRAHGVADRVDIVGGSFFDAVPDG-DAYV
MSMEG_0367|M.smegmatis_MC2_155      APQAKGVLYDLPNVVEGAPEMLARHGVADRVQVIPGSFFDEVPDGADLYV
Mflv_3940|M.gilvum_PYR-GCK          AAGARGILFDLPAVVAGAAPLLADAGVADRCTVSGGSFLESVPAGGDVYV
Mvan_2460|M.vanbaalenii_PYR-1       TPTARGVLFDRPSVVAGADSVLGPAGVAARCRTEGGSFFEAVPAGGDAYV
Mb0582|M.bovis_AF2122/97            HPHLQCVSLDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVIT
Rv0567|M.tuberculosis_H37Rv         HPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVIT
MMAR_0934|M.marinum_M               HPHLQCISFDLPAVTDITRRKLSEQGLGDRVRAVSGDFFADPLPSADVIT
MUL_0686|M.ulcerans_Agy99           HPHLQCISFDLPAVTDITRRKLSEQGLGDRVRAVSGDFFADPLPSADVIT
                                     .  : :  * * *.  :   *   *:. *     *.*:     . *  .

TH_3167|M.thermoresistible__bu      LKNVIHDWDDDEALPILGNIRSALSDRGAILLVEMVIPSHHR-EFLGNMV
MSMEG_0367|M.smegmatis_MC2_155      MKNIIHDWADAPAAEILRNVRAAARTGATLLLVEGVIPDHDR-AFPLKWV
Mflv_3940|M.gilvum_PYR-GCK          MKNIVHDWDDTDAATILRNVRTAIAEGGKLVLLEMVLPERAS-SFIGHML
Mvan_2460|M.vanbaalenii_PYR-1       MKAIIHDWGDDQSLSILRNVRTAIADDGRLLLFEMVLPERAP-AHLGFMV
Mb0582|M.bovis_AF2122/97            MGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMM
Rv0567|M.tuberculosis_H37Rv         MGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMM
MMAR_0934|M.marinum_M               MGQILHDWNLDGKQRLIAKAYEALPEGGAFIAIETLIDDARRKNTAGLMM
MUL_0686|M.ulcerans_Agy99           MGQILHDWNLDGKQRLIAKAYEALPEGGAFTAIETLIDDARRKNTAGLMM
                                    :  ::***       :: :   *    . :  .* :: .          :

TH_3167|M.thermoresistible__bu      DLEMLNGG-NARERTADEYRSLLARANLRMTRVVATAGPYSVIEARAA
MSMEG_0367|M.smegmatis_MC2_155      DMEMLIGN-AARERTEAQYRKLYTEAGFRLTRVVPTACPYSLIEGVAI
Mflv_3940|M.gilvum_PYR-GCK          DLEMLLML-RGKERTRAQYSELLEAAGFQLTRVIPTVSPISVIEARAV
Mvan_2460|M.vanbaalenii_PYR-1       DLEMLVTA-GGRERTASQYAKLLADSGFRMTRVIPTASPLSIVEAVPA
Mb0582|M.bovis_AF2122/97            SLNMLIEFGDAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK-
Rv0567|M.tuberculosis_H37Rv         SLNMLIEFGDAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK-
MMAR_0934|M.marinum_M               SLNMLIEFGDAFDYTGADFRKWCGAAGFRSFEVIALAAGSSAAVAYK-
MUL_0686|M.ulcerans_Agy99           SLNMLIEFGDAFDYTGADFRKWCGAAGFRSFEVIALAAGSSAAVAYK-
                                    .::**     . : :  ::      :.::  .*:. .   *   .