For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MDQSSPDRIMAIGAGYGPSKVLLTAVGLGLFTELGDRAMTAQAIAELLGLVPRPATDFLDALVSLDLLAR DGDGPDARYRNTAETARYLDEASPEYQGGLLKIWDQRNYRFWADLTDALQTGKPQNEIKQTGRPFFETVY ADPRRLEVFLGAMDSASRRNCELLVKRFPFQRYGSLCDVGGANGLLSRTAAAAHPHLQCISFDLPAVTDI TRRKLSEQGLGDRVRAVSGDFFADPLPSADVITMGQILHDWNLDGKQRLIAKAYEALPEGGAFIAIETLI DDARRKNTAGLMMSLNMLIEFGDAFDYTGADFRKWCGAAGFRSFEVIALAAGSSAAVAYK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0934 | - | - | 100% (340) | methyltransferase/methylase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0582 | - | 1e-157 | 80.06% (336) | methyltransferase/methylase |
| M. gilvum PYR-GCK | Mflv_3940 | - | 1e-24 | 26.96% (319) | O-methyltransferase family protein |
| M. tuberculosis H37Rv | Rv0567 | - | 1e-158 | 80.36% (336) | methyltransferase/methylase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_5354 | - | 3e-22 | 27.73% (321) | O-methyltransferase, family protein 2 |
| M. thermoresistible (build 8) | TH_3167 | - | 2e-28 | 28.78% (337) | PUTATIVE hydroxyneurosporene-O-methyltransferase |
| M. ulcerans Agy99 | MUL_0686 | - | 0.0 | 99.12% (340) | methyltransferase/methylase |
| M. vanbaalenii PYR-1 | Mvan_2460 | - | 4e-23 | 26.59% (331) | O-methyltransferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3940|M.gilvum_PYR-GCK -----------------MTHTSTPRGSAARSAPNRVPPVRLIRAVDRLRA
Mvan_2460|M.vanbaalenii_PYR-1 ----------------------------MRTMLMTPPPVVLA-AVGRFRG
TH_3167|M.thermoresistible__bu LQTEYVEVTRIAPVRSRRYDPITRSGGVVMSARVRVPPARIARTADAARH
MSMEG_5354|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0934|M.marinum_M --------------------------------------------------
MUL_0686|M.ulcerans_Agy99 --------------------------------------------------
Mb0582|M.bovis_AF2122/97 --------------------------------------------------
Rv0567|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3940|M.gilvum_PYR-GCK GLQRLHRSTAPGNVALMELATGAWTTQVLYVAATLGIPDELADGPAHAAD
Mvan_2460|M.vanbaalenii_PYR-1 LLDRLHTLTAPSHIAVLELSLGSWFTAALYATVRLGIADALADGPLRADD
TH_3167|M.thermoresistible__bu YLLRLQQKLTAPQAVMLEMILAGWTSQALTTAADLGVADALADGPLAIGD
MSMEG_5354|M.smegmatis_MC2_155 MATRSIPAALPDYERMMAMLTGFWVTQIVRAAAVFNLADHLASGTDTAVA
MMAR_0934|M.marinum_M -------MDQSSPDRIMAIGAGYGPSKVLLTAVGLGLFTELGDRAMTAQA
MUL_0686|M.ulcerans_Agy99 -------MDQSRPDRIMAIGAGYGPSKVLLTAVGLGLFTELGDRAMTAQA
Mb0582|M.bovis_AF2122/97 -------MELS-PDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEA
Rv0567|M.tuberculosis_H37Rv -------MELS-PDRIMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEA
. :: : . : : .:. :.: *.. .
Mflv_3940|M.gilvum_PYR-GCK VATRVGADAGAVYRLMRAMVSRGALREERDG---RFALTPVGDALRTDSE
Mvan_2460|M.vanbaalenii_PYR-1 VARKVGADPEATYRLMRALASRSVLKLRRDG---RFALTRLGHALRVDHP
TH_3167|M.thermoresistible__bu LARKVDADPERLARLMCALTSRGVFRQRRDG---RYALNALATTLRSDAS
MSMEG_5354|M.smegmatis_MC2_155 IASAEATDVDATRRLLRACATLGLVTSADGE---HFAGTSLLSTLRKDEP
MMAR_0934|M.marinum_M IAELLGLVPRPATDFLDALVSLDLLARDGDGPDARYRNTAETARYLDEAS
MUL_0686|M.ulcerans_Agy99 LAELLGLVPRPATDFLDALVSLDLLARDGDGPDARYRNTAETARYLDEAS
Mb0582|M.bovis_AF2122/97 IADRLGLLKRPAIDFLDALVSLDLLARDGDGPGSHYRNTPETAHFLDEAR
Rv0567|M.tuberculosis_H37Rv IADRLGLLKRPAIDFLDALVSLDLLARDGDGPGSHYRNTPETAHFLDEAR
:* :: * .: . . . :: . :
Mflv_3940|M.gilvum_PYR-GCK GSLRDMVLFIGHPARWADWGSLEYSVRTGEPAADMLRGMP-FFDYLDTDP
Mvan_2460|M.vanbaalenii_PYR-1 ESMAPLIAFVGSRQHWEHWGELLYSVQTGRTAVEKLRGSE-FFEYLDTDP
TH_3167|M.thermoresistible__bu ASLAGAARFYGSRLHREHWSMLTDSVRTGKPGVPTLRGMD-WWQFSAANP
MSMEG_5354|M.smegmatis_MC2_155 NSLRGMVLSHTAPGHWLPWGLLPDAIRSGERQIKAAHGTETYFDYLAENL
MMAR_0934|M.marinum_M PEYQGGLLKIWDQRNYRFWADLTDALQTGKPQNEIKQTGRPFFETVYADP
MUL_0686|M.ulcerans_Agy99 PEYQGGLLKIWDQRNYRFWADLTDALQTGKPQNEIKQTGRPFFETVYADP
Mb0582|M.bovis_AF2122/97 PTYAGGLLKIWNERNYRFWADLTEALKTGKAQSEVKQTGRPFFEALYADP
Rv0567|M.tuberculosis_H37Rv PTYAGGLLKIWNERNYRFWADLTEALKTGKAQSEVKQTGRPFFEALYADP
. *. * ::::*. : ::: :
Mflv_3940|M.gilvum_PYR-GCK EFATVFNNAMTAASGLSDDVALQACDFTGARLVVDVGGGHGAVLATILRS
Mvan_2460|M.vanbaalenii_PYR-1 AFAKVFNESMTGGSRAVIENAIPAYDFSDRRLIVDVGGGEGGLLAAILNR
TH_3167|M.thermoresistible__bu EFGDLFNGAMTSISELSAPVVAAAYDFSPFPTIVDVGGGHGRLLSAILAA
MSMEG_5354|M.smegmatis_MC2_155 EQAGHFTEAMSNLSAAAAVEVAEVLDTRGVDYALDVGGANGELVRALMRA
MMAR_0934|M.marinum_M RRLEVFLGAMDSASRRNCELLVKRFPFQRYGSLCDVGGANGLLSRTAAAA
MUL_0686|M.ulcerans_Agy99 RRLEVFLGAMDSASRRNCELLVKRFPFQRYGSLCDVGGANGLLSRTAAAA
Mb0582|M.bovis_AF2122/97 RRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADGLLSRIVAAA
Rv0567|M.tuberculosis_H37Rv RRLEAFMAAMDAASRRNIELLAKRFPFERYRRLCDVGCADGLLSRIVAAA
* :* * *** ..* :
Mflv_3940|M.gilvum_PYR-GCK AAGARGILFDLPAVVAGAAPLLADAGVADRCTVSGGSFLESVPAGGDVYV
Mvan_2460|M.vanbaalenii_PYR-1 TPTARGVLFDRPSVVAGADSVLGPAGVAARCRTEGGSFFEAVPAGGDAYV
TH_3167|M.thermoresistible__bu TPTARGVLFDLPDVVADAPALLRAHGVADRVDIVGGSFFDAVPDG-DAYV
MSMEG_5354|M.smegmatis_MC2_155 NPELRGGVFDLPHVVADAVEAAHRDGLQGRFTARGGDFFESVPPA-DLYT
MMAR_0934|M.marinum_M HPHLQCISFDLPAVTDITRRKLSEQGLGDRVRAVSGDFFADPLPSADVIT
MUL_0686|M.ulcerans_Agy99 HPHLQCISFDLPAVTDITRRKLSEQGLGDRVRAVSGDFFADPLPSADVIT
Mb0582|M.bovis_AF2122/97 HPHLQCVSLDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVIT
Rv0567|M.tuberculosis_H37Rv HPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVIT
. : :* * *. : *: * .*.*: . * .
Mflv_3940|M.gilvum_PYR-GCK MKNIVHDWDDTDAATILRNVRTAIAEGGKLVLLEMVLPERASSFIG-HML
Mvan_2460|M.vanbaalenii_PYR-1 MKAIIHDWGDDQSLSILRNVRTAIADDGRLLLFEMVLPERAPAHLG-FMV
TH_3167|M.thermoresistible__bu LKNVIHDWDDDEALPILGNIRSALSDRGAILLVEMVIPSHHREFLG-NMV
MSMEG_5354|M.smegmatis_MC2_155 LKYILHDWDDESCVRILKTCRAALQDGGRIVVIDHLVGDLDAADTT-TMM
MMAR_0934|M.marinum_M MGQILHDWNLDGKQRLIAKAYEALPEGGAFIAIETLIDDARRKNTAGLMM
MUL_0686|M.ulcerans_Agy99 MGQILHDWNLDGKQRLIAKAYEALPEGGAFTAIETLIDDARRKNTAGLMM
Mb0582|M.bovis_AF2122/97 MGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMM
Rv0567|M.tuberculosis_H37Rv MGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETLIDDARRENTTGLMM
: ::***. :: . *: . * : .: :: . *:
Mflv_3940|M.gilvum_PYR-GCK DLEMLLML-RGKERTRAQYSELLEAAGFQLTRVIPTVSPISVIEARAV
Mvan_2460|M.vanbaalenii_PYR-1 DLEMLVTA-GGRERTASQYAKLLADSGFRMTRVIPTASPLSIVEAVPA
TH_3167|M.thermoresistible__bu DLEMLNGG-NARERTADEYRSLLARANLRMTRVVATAGPYSVIEARAA
MSMEG_5354|M.smegmatis_MC2_155 DVNMLVMT-GGRERDIAEFDALFAAAGLRRTEVG-RAGQFAIIETVAV
MMAR_0934|M.marinum_M SLNMLIEFGDAFDYTGADFRKWCGAAGFRSFEVIALAAGSSAAVAYK-
MUL_0686|M.ulcerans_Agy99 SLNMLIEFGDAFDYTGADFRKWCGAAGFRSFEVIALAAGSSAAVAYK-
Mb0582|M.bovis_AF2122/97 SLNMLIEFGDAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK-
Rv0567|M.tuberculosis_H37Rv SLNMLIEFGDAFDYSAADFRGWCGEAGFRSFEVIPLAGGSSAAVAYK-
.::** . : :: :.:: .* .. : :