For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VADRPLLYLGRVCSLTRPQLIERPADLTAEWLTDILGHGQVESFTVDRIGTGQMSECYRVGIRYAGGGVG PASVVLKVAAAEPSSRQTGLAMGLYEREVRFYTDIAPSLGGPVAPCHHTAYDPDTGAFDLVLADAAPASV GDEIRGATAEQASLAMTQLGLVHGPLLGSEALEGADWLNRESPVNQGLVAALYAGYIDRYSDQIAPEHRV VCERLVASFDAYMAAEDAAGGPRGLVHGDFRLDNMLFGQDGSDRPLTVVDWQTVTWGPAFTDVSYFLGGS LPIEERRAHYDELLAAYHRALGEATGVSLDDVREGVRHQSFFGVLMAIVSSMLVGRTERGDEMFMALIAR HCQHVLDTDALAILPAPSTPEPLQPNADDEGRHAPTEEPLWSESWYFDFAAPSQDIGGWIRLGLMPNEGH AWVNGLLCGPGMPTIAALDFEAPLPEEHTRVHGQDIELEQTVIEPLQTYQVTVRGRGQAHDDPAALLRGE PGRDVEVTMDLTWTSVGQPYQYRVSPRYEIPCTVTGTVSADGHTYEFDAVVGQRDHSWAARDWWAMDWVW SAFHLEDGTHIHGVEILIPGAPPMSIGYLQRAGEPLVELSSVSAQTTFADNDLPQSAVLDYGDLRVDVTV RGHAPVLLTSADGRLSQFPRAWATVTTDDGRTGAGWIEWNRNLAQPDG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3155 | - | - | 100% (678) | hypothetical protein Mflv_3155 |
| M. gilvum PYR-GCK | Mflv_3102 | - | 3e-39 | 33.97% (365) | aminoglycoside phosphotransferase |
| M. gilvum PYR-GCK | Mflv_4117 | - | 2e-21 | 26.94% (360) | hypothetical protein Mflv_4117 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3019 | - | 0.0 | 61.37% (655) | hypothetical protein MMAR_3019 |
| M. avium 104 | MAV_2467 | - | 0.0 | 61.54% (663) | phosphotransferase enzyme family protein |
| M. smegmatis MC2 155 | MSMEG_3846 | - | 0.0 | 64.65% (662) | phosphotransferase enzyme family protein |
| M. thermoresistible (build 8) | TH_2511 | - | 0.0 | 63.31% (665) | PUTATIVE protein of unknown function DUF227 |
| M. ulcerans Agy99 | MUL_1045 | - | 3e-18 | 29.32% (307) | hypothetical protein MUL_1045 |
| M. vanbaalenii PYR-1 | Mvan_3374 | - | 0.0 | 77.51% (658) | aminoglycoside phosphotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3155|M.gilvum_PYR-GCK --MADRPLLYLGRVCSLTRPQLIERPADLTAEWLTDIL-----GHGQVES
Mvan_3374|M.vanbaalenii_PYR-1 -----------------MRPRLIERPPDLTAEWLTAVI-----GQGTVTE
MSMEG_3846|M.smegmatis_MC2_155 --------------MQPTMNAVIERPDDLTGEWLTAAL-----GAGRVTD
TH_2511|M.thermoresistible__bu --------------VQPTRNRVIERPTDLTTHWLTEKLTAGTPGAGRVTD
MMAR_3019|M.marinum_M -----------MNDEGDQNAGIIEEPGDLTASWLTEKI-----GAGDVTE
MAV_2467|M.avium_104 -----------MHAETEQ---VIERPSDLSASWLAAVI-----GTGPIAD
MUL_1045|M.ulcerans_Agy99 MIALARLATHLGRGLGRVATDAVLRNARAFPRRIHDLDP---PALSEIMG
: . : . . :
Mflv_3155|M.gilvum_PYR-GCK FTVDRIGTGQMSECYRVGIRYAGGGVG-PASVVLKVAAAEPSSRQTGLAM
Mvan_3374|M.vanbaalenii_PYR-1 FTVDRIGTGQMSECYRVALSYADDGAG-PATVVLKVAAADPSSRQTGLAM
MSMEG_3846|M.smegmatis_MC2_155 FSFERIGTGQMSECYRVTLRYA-DGTDGPASVVLKVAATDPNSRQTGLAL
TH_2511|M.thermoresistible__bu FTVERIGTGQMSECYRVTLSWTGDGADRPASVVLKVAASDPTSRQTGVSL
MMAR_3019|M.marinum_M FAVERIGTGQMSECYRVQLTYAVP--GGPSLVVLKVAATDPMSRQTGQAL
MAV_2467|M.avium_104 FSVERIGTGQMSECYRIRLRYAQADARGPESVVLKVAATDPVSRQTGLAL
MUL_1045|M.ulcerans_Agy99 RRVSSVSVLDDSSGTTSRARLALSGNDVPESVFVKMAAATAATRFIGELG
.. :.. : *. : * *.:*:**: . :* *
Mflv_3155|M.gilvum_PYR-GCK GLYEREVRFYTDIAPSLG-GPVAPCHHTAYDPDTGAFDLVLADAAPASVG
Mvan_3374|M.vanbaalenii_PYR-1 GLYEREVRFYTDIAPGLG-GPVAPCHHGAYDPHTGAFDLLLADAAPALVG
MSMEG_3846|M.smegmatis_MC2_155 GLYEREVRFYTEIAPQLGAGPIAPCYHSAFDPQTGAFDLLLGDAAPATVG
TH_2511|M.thermoresistible__bu GLYEREVRFYADIAPRLTGGPIAPCYHAAYDPDSGAFDLLLGDAAPAQVG
MMAR_3019|M.marinum_M GLYEREVRFYAEVAPRLG-GPIAPCYHAAVDAQTGAFDLLLGDAGPALVG
MAV_2467|M.avium_104 GLYEREVRFYGDVAPRLG-GPIAPCYHAAVDTSTGVFDLLLGDAGPAVVG
MUL_1045|M.ulcerans_Agy99 RLAETEVSFYRDLSPELA-PDAPTAYGCAFDPLTGRFVLVLEDLAAPAEG
* * ** ** :::* * ...: * *. :* * *:* * ... *
Mflv_3155|M.gilvum_PYR-GCK -----DEIRGATAEQASLAMTQLGLVHGPLLGSEA-LEGADWLNRESPVN
Mvan_3374|M.vanbaalenii_PYR-1 -----DEIRGATVEEAMLAVTQIGLVHGPLLNDEA-LAGADWLNRESPVN
MSMEG_3846|M.smegmatis_MC2_155 -----NELQGATVEQATLALVQLGHVHGAAHASSRGAAIADWLVREAPVS
TH_2511|M.thermoresistible__bu -----DEIRGATPEQAKLALAELGKVHAPLLGDEQ-LGGAEWLNRDAPID
MMAR_3019|M.marinum_M -----DEIAGATVAQAQLAVSQLGRLHGPLLGDAA-LAEAPWLNRDSPLN
MAV_2467|M.avium_104 -----DEIAGATIEQARLGVVELGRLHGPLLGDIS-LAQAPWLNRDAPLN
MUL_1045|M.ulcerans_Agy99 TCDFSDTLHPFDNDQAALVVELLARLHATYWVRLN-HGGVRPFGWRYAAS
: : :* * : :. :*.. . : . .
Mflv_3155|M.gilvum_PYR-GCK QGLVAALYAGYIDRYSDQIAPEHRVVCERLVASFDAYMAAEDAAG-GPRG
Mvan_3374|M.vanbaalenii_PYR-1 QGLISALYAGYIDRYREQIAPEHRNVCERFVESFDAYMAAENDAD-TPRG
MSMEG_3846|M.smegmatis_MC2_155 QPMLAGLYAAFVERYADMITPQQREVCERLVESFDSYLAAEDE---RPKG
TH_2511|M.thermoresistible__bu QALLAQLYAGFVERYGNLVSDAHRLVCERLIAAFDDYLAAEAAG--RPHG
MMAR_3019|M.marinum_M QAMVNGLYAGFLDRYGEQIDPRSRMVCERLVAAFDGYLAQESSRG-AIQG
MAV_2467|M.avium_104 QAMIAPLYAGFVERYGDQIAPEHRAVCERLVAAFDGYLAQEP----GVRG
MUL_1045|M.ulcerans_Agy99 RDPSVPLVPTMLRASWRRLGGHAAALLPGRDFVFEHYRAITGLIDAPPHT
: * . : : : *: * * :
Mflv_3155|M.gilvum_PYR-GCK LVHGDFRLDNMLFGQDGSDRPLTVVDWQTVTWGPAFTDVSYFLGGSLPIE
Mvan_3374|M.vanbaalenii_PYR-1 LVHGDYRLDNMLFGQDGAHRPLTVVDWQTVTWGPAFSDVAYFLGCALPVE
MSMEG_3846|M.smegmatis_MC2_155 LVHGDYRLDNMLFGDPGADRPLTAVDWQTVTWGPALTDVAYFVGSSLPSE
TH_2511|M.thermoresistible__bu LVHGDFRLDNMLFGDPHAARPLTAVDWQTVAWGPALTDVAYFLGCALKTE
MMAR_3019|M.marinum_M LVHGDYRLDNLLFGAAGAERPLTVVDWQTVSWGPALTDLAYFLGCALQPN
MAV_2467|M.avium_104 LVHGDYRLDNMLFGTAGAERALTVVDWQTVSWGPALTDLAYFLGCALPTE
MUL_1045|M.ulcerans_Agy99 VLHGDAHPGNWYFRSSGGPLAAGLLDWQAIRLGHPARDLAYTLITGMTTT
::*** : .* * . . :***:: * . *::* : .:
Mflv_3155|M.gilvum_PYR-GCK ERRAHYDELLAAYHRALGEATGVSLDDVREGVRHQSFFGVLMAIVSSMLV
Mvan_3374|M.vanbaalenii_PYR-1 QRREHYDALLAAYHGALGPTAGVSIDEVREGVRRQSFFGVLMSIVSPMLV
MSMEG_3846|M.smegmatis_MC2_155 VRREHYDALLRAYHEALGPDAPLTLDQVREDVRRQSFFGVVMAIVSSMLV
TH_2511|M.thermoresistible__bu DRRAHYDELLRAYHDALGPEPALTLDEVRDRVRRQTFTGVVMAIVPAMLV
MMAR_3019|M.marinum_M ERRAHYDDLLRTYHDALGPQAPITLEQVADEVRRQSFFGVMMAIVSSMLV
MAV_2467|M.avium_104 DRREHYDALLRAYHEALGPQPPITLADVADGVRRQSFFGVMMAIVSSMLV
MUL_1045|M.ulcerans_Agy99 DRRVTERELLDVYRRALAAAGGPELDREEPWLRYR---------------
** ** .*: **. : :* :
Mflv_3155|M.gilvum_PYR-GCK GRTERGDEMFMALIARHCQHVLDTDALAILPAPSTPEPLQPNADDEGRHA
Mvan_3374|M.vanbaalenii_PYR-1 ERTERGDEMFMAMIARHCQHVIDTGALAVLPEPGTPEPLQPNADDEGRHS
MSMEG_3846|M.smegmatis_MC2_155 ERTERGDQMFMTMLDRNCSHVLDTGALDILAPPVPVAPLQPAAEDDDAHT
TH_2511|M.thermoresistible__bu ERTERGDEMFLTLLGRHCDHVLDTGALDILPPPAAPEPLRPEPADEYPHR
MMAR_3019|M.marinum_M ERTDRGDRLFMTMLHRHCEHVLDTDALATLPDAAPPEPLCPGEQDEMAHE
MAV_2467|M.avium_104 ERTDRGDQMFMTMLRRHCDHVLDTDALATLPAASAPEPLQPSPEDELAHD
MUL_1045|M.ulcerans_Agy99 -------------QAAACAYVATT--------------------------
* :* *
Mflv_3155|M.gilvum_PYR-GCK PTEEPLWSESWYFDFAAPSQDIGGWIRLGLMPNEGHAWVNGLLCGPGMPT
Mvan_3374|M.vanbaalenii_PYR-1 PTDEALWSESWYFDFADPGQQLGGWIRLGLIPNQDHAWINGLWCAPGGPT
MSMEG_3846|M.smegmatis_MC2_155 PGDEPLWNESWYFDFVDTAAGFGGWIRLGLIPNQDHSWINVLVCGPDLPT
TH_2511|M.thermoresistible__bu PTDEPLWNESWYFDFVDAEQGVGGWVRLGLMPNEGVAWVNALLCGPDMPT
MMAR_3019|M.marinum_M PTDEPLWSESWYADFVDAAQGLGGWFRLGRIANQQKAWVHALLCGPDMAT
MAV_2467|M.avium_104 PTTEPLWSESWYADFADPAQGLGGWFRLGLVANQQTAWVHALVCGPDMPT
MUL_1045|M.ulcerans_Agy99 -----------------IAAGLG-----------GMQAADIALTGLDLTV
.* . . . ..
Mflv_3155|M.gilvum_PYR-GCK IAALDFEAPLPEEHTRVHGQDIELEQTVIEPLQTYQVTVRGRGQAHDDPA
Mvan_3374|M.vanbaalenii_PYR-1 IAVLDFEAPLPEDHTHVAADGIELDLEVLEPLSSYRVVLRGRGEAHDDPA
MSMEG_3846|M.smegmatis_MC2_155 VALNDFHAALPTDVARVCGDGVELSLQRGEPLQTYRVTASGQGQAYDDPA
TH_2511|M.thermoresistible__bu IALTEWEAPLPADPFRTRTGTAELDMEATDPLRSYRVTVRGRGQSYDDPA
MMAR_3019|M.marinum_M VAVADIEVALPDDPWAVRTGDIELRHHATAPLQTYAVQLRARGQAYEDPS
MAV_2467|M.avium_104 VAV-DAQVPLPPDPWTVRTDTFEITHSAGAPLRSYRVDVRALAQAYADPA
MUL_1045|M.ulcerans_Agy99 AALHDLQT----------------------------------------VA
* : .. :
Mflv_3155|M.gilvum_PYR-GCK ALLRGEPGRDVEVTMDLTWTSVGQPYQYRVSPRYEIPCTVTGTVSADGHT
Mvan_3374|M.vanbaalenii_PYR-1 ALLRGEAGRPVDVSMDLTWSTVGRPYQYRMSPRYEIPCTVTGTVVADGRT
MSMEG_3846|M.smegmatis_MC2_155 ALLRGEAGTPVDVTLDLTWTTVGTPYQYRITPRYEIPCTVTGTVTVGETV
TH_2511|M.thermoresistible__bu VLLAGGAGEPVELTFDLEWTSAGTPYQYRITPRFEIPCTVSGTVTAGDRS
MMAR_3019|M.marinum_M ALLRGEPGDPVEVTMNLVWTTNGVPYRYRLTSRYEIPCTVAGTVTVDGTH
MAV_2467|M.avium_104 ALLRGEPGTPVAMTMNLDWHTDGTPYKYAMTTRYEIPCTVTGSVTIGDTA
MUL_1045|M.ulcerans_Agy99 ALRAADLG--------------GTSWAWRPG------MARSARIRPGASA
.* . * * .: : : :. : .
Mflv_3155|M.gilvum_PYR-GCK YEFDAVVGQRDHSWAARDWWAMDWVWSAFHLEDGTHIHGVEILIPGAPPM
Mvan_3374|M.vanbaalenii_PYR-1 YAIAGVPGQRDHSWAARDWWSMDWMWSALHLDDGTHIHGVEILIPGMPPL
MSMEG_3846|M.smegmatis_MC2_155 HPLEAVVGQRDHSWGVRDWWSMEWVWSALHLDDGTHLHGVDLRIPNMPPL
TH_2511|M.thermoresistible__bu YTVTAVPGQRDHSWGVRDWWGMEWVWSALHLDDGTRLHGVDVRIPDMGPI
MMAR_3019|M.marinum_M YRVDAVPGQRDHSWGVRDWWSMDWMWSALHLDDGTHLHGVNIQLPGTPAF
MAV_2467|M.avium_104 YRIESVAGQRDHSWGVRDWWSMDWIWSALHLDDGTHLHGVNIRIPGAPAF
MUL_1045|M.ulcerans_Agy99 RRCPMVWSTSSHILGVSRHFAMGAW-------------------------
* . .* .. :.*
Mflv_3155|M.gilvum_PYR-GCK SIGYLQRAGEPLVELSSVSAQTTFADNDLPQSAVLDYG--DLRVDVTVRG
Mvan_3374|M.vanbaalenii_PYR-1 AVGYVQRDGESLVELAKVSARTTFADNGLPISAQVDYAPGDITATIDVRG
MSMEG_3846|M.smegmatis_MC2_155 GVGYTQR-DGELVELQSVTAQHTLGDDDLPVTTTLTLQPGDIEATVDIQG
TH_2511|M.thermoresistible__bu GIGYIQPPDGPLLELSGVRARETVAGTGLPVATTIELTPGDVSVDIDIQG
MMAR_3019|M.marinum_M SVGYVQDSGGNLTELQAVNFREAFGSNGLPQNTTLILKPGDITANIDVRA
MAV_2467|M.avium_104 SIGYTQGADGEVTELQTVDSRESFGDNGLPLDATLELNPGEITAQVDVRG
MUL_1045|M.ulcerans_Agy99 --------------------------------------------------
Mflv_3155|M.gilvum_PYR-GCK HAPVLLTSADGRLSQFPRAWATVTTDDGRTGAGWIEWNRNLAQPDG
Mvan_3374|M.vanbaalenii_PYR-1 HAPVLLTSPDGRHSRFPRAWGEVTTADGRTGVGWIEWNRSQD----
MSMEG_3846|M.smegmatis_MC2_155 HAPVKLVSAEGKVSQFPRAWATVRTADGRTGVGWLEWNRNLG----
TH_2511|M.thermoresistible__bu HAPVRLTAPDGRVSHFPRAWCRVTTADGRTGVGWVEWNRVQT----
MMAR_3019|M.marinum_M HAPVRLNASDWRVSHFPRAWVAVVTTDGRSGVGWMEWNRNQV----
MAV_2467|M.avium_104 QAPVRLVAADGRVSQFPRVWAAVSTGDGRRGVGWLEWNRNLGERIG
MUL_1045|M.ulcerans_Agy99 ----------------------------------------------