For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_3384 (-)

annotation: acyl-CoA dehydrogenase domain protein
coordinates: 904240 - 905433
length: 398

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_3384 - - 100% (398) acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8) TH_3837 - e-100 46.88% (384) PUTATIVE Butyryl-CoA dehydrogenase
M. thermoresistible (build 8) TH_4603 - 2e-67 36.17% (376) PUTATIVE acyl-CoA dehydrogenase domain protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0221c fadE3 6e-94 44.70% (387) acyl-CoA dehydrogenase FADE3
M. gilvum PYR-GCK Mflv_4367 - 0.0 91.44% (397) butyryl-CoA dehydrogenase
M. tuberculosis H37Rv Rv0215c fadE3 1e-83 44.01% (359) acyl-CoA dehydrogenase FADE3
M. leprae Br4923 MLBr_00737 fadE25 2e-59 35.16% (384) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_1188c - 2e-63 36.46% (384) acyl-CoA dehydrogenase
M. marinum M MMAR_4030 - 0.0 87.88% (396) acyl-CoA dehydrogenase
M. avium 104 MAV_1575 - 0.0 89.92% (397) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_2208 - 0.0 90.18% (397) acyl-CoA dehydrogenase
M. ulcerans Agy99 MUL_3895 - 0.0 87.12% (396) acyl-CoA dehydrogenase
M. vanbaalenii PYR-1 Mvan_1977 - 0.0 90.93% (397) butyryl-CoA dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mb0221c|M.bovis_AF2122/97           ----------MRNELNDDEAMLVATVRAFIDRDVKPTVREVEHANSYPEA
Rv0215c|M.tuberculosis_H37Rv        ----------MRNELNDDEAMLVATVRAFIDRDVKPTVREVEHANSYPEA
Mflv_4367|M.gilvum_PYR-GCK          -----MSRLAQTLGLTEFQTEIVSTVRQFVDKEVIPTAQELEHADTYPQA
Mvan_1977|M.vanbaalenii_PYR-1       -----MTKLAQTLGLTEFQAEIVSTVRQFVDKEVIPTAQELEHSDTYPQA
MSMEG_2208|M.smegmatis_MC2_155      -----MTKLAQTLGLTEFQTEIISTVRQLVDKEIIPAAQELEHSDTYPQA
TH_3384|M.thermoresistible__bu      -----MTRLAQTLGLTEFQTEILRTVREFVDREIIPNAAEFERTDTYPQP
MAV_1575|M.avium_104                -----MTRLAQTLGLTEFQTEIIATVRQFVDKEVIPHAAELERADTYPQD
MMAR_4030|M.marinum_M               -----MTKLAQTLGLTELQAEIVATVRQFVDKEVIPNASELERKDAYPHE
MUL_3895|M.ulcerans_Agy99           -----MTKLAQTLGLTELQAEIVATVRQFVDKEVIPNASELERKDAYPHE
MLBr_00737|M.leprae_Br4923          MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
MAB_1188c|M.abscessus_ATCC_199      -----------MFNLTEEQREIWNTAREFADIHIAPHALDWDRDKYFPVE
                                                  * : .  :  * * : : .: * . : ::   :*  

Mb0221c|M.bovis_AF2122/97           WIEQMKHIGIYGLAIDEQYGGSPVSMPCYVQVTQELARGWMSLAGAMGGH
Rv0215c|M.tuberculosis_H37Rv        WIEQMKHIGIYGLAIDEQYGGSPVSMPCYVQVTQELARGWMSLAGAMGGH
Mflv_4367|M.gilvum_PYR-GCK          IVDAMREMGLFGLMIPEEYGGLGESLLTYALCVEELARGWMSVSGVINTH
Mvan_1977|M.vanbaalenii_PYR-1       IVDAMKEMGLFGLMIPEEYGGLGESLLTYALCVEELARGWMSVSGVINTH
MSMEG_2208|M.smegmatis_MC2_155      IVDQMKQMGLFGLMIPEEYGGLGESLLTYALCVEELARGWMSVSGVINTH
TH_3384|M.thermoresistible__bu      IVDQMREMGLFGLMIPEEYGGLGESLLTYALCVEELARGWMSISGVINTH
MAV_1575|M.avium_104                IVDQMRDMGLFGLMIPQEYGGLGESLLTYALCVEELARGWMSVSGVLNTH
MMAR_4030|M.marinum_M               IVEQMRSIGLFGLMIPEQYGGLGESLLTYALCVEELARGWMSVSGVLNTH
MUL_3895|M.ulcerans_Agy99           IVEQTRSIGLFGLMIPEQYGGLGESLLTYALCVEELARGWMSVSGVLNTH
MLBr_00737|M.leprae_Br4923          ALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
MAB_1188c|M.abscessus_ATCC_199      IFPKAAALGMGGIYVNPDVGGSGLTRLDASLIFEAMATGCSAVSAFISIH
                                     .      *: .: :  : **            : :*    : :     :

Mb0221c|M.bovis_AF2122/97           TVVAKLLTLFGTEEQRRTYLPPMASGELRATMALTEPGGGSDLQNMSTTA
Rv0215c|M.tuberculosis_H37Rv        TVVAKLLTLFGTEEQRRTYLPPMASGELRATMALTEPGGGSDLQNMSTTA
Mflv_4367|M.gilvum_PYR-GCK          FIVAYMIRQHGTDAQKSHYLPRMATGETRGAFSMSEPELGSDVAAIRTRA
Mvan_1977|M.vanbaalenii_PYR-1       FIVAYMIRQHGTDAQKSRYLTRMATGETRGAFSMSEPELGSDVAAIRTRA
MSMEG_2208|M.smegmatis_MC2_155      FIVAYMIRQHGTDEQKRKFLPRMATGETRGAFSMSEPELGSDVAAIRTRA
TH_3384|M.thermoresistible__bu      FIVAYMIRQHGTEEQKQRFLPRMATGETRGAFSMSEPELGSDVAAIRTRA
MAV_1575|M.avium_104                FIVAYMLRQHGTDEQKQRFLPRMAVGETRGAFSMSEPELGSDVAAIRTRA
MMAR_4030|M.marinum_M               FIVAYMLRQHGTEEQRQRFLPRMATGESRGAFSMSEPELGSDVAAIRTRA
MUL_3895|M.ulcerans_Agy99           FIVAYMLRQHGTEEQRQRFLPRMATGESRGAFSMSEPELGSDVAAIRTRA
MLBr_00737|M.leprae_Br4923          KLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRTRA
MAB_1188c|M.abscessus_ATCC_199      NMAAWMIDEFGDEEQRRRWLPSMCTMETIGAYCLTEPECGSDAAALRTSA
                                     : :  :   * :  :   *. :.     .: .::*   ***   : * *

Mb0221c|M.bovis_AF2122/97           LADGPEGSAGLLINGCKTWISNARRSGLFAVLCKTDPNATPRHQGMSIVL
Rv0215c|M.tuberculosis_H37Rv        LADGPEGSAGLLINGCKTWISNARRSGLFAVLCKTDPNATPRHQGMSIVL
Mflv_4367|M.gilvum_PYR-GCK          KNNG---DGTYTIDGQKMWLTNGGSSTLVATLVRTDEGADKPHRNLTAFL
Mvan_1977|M.vanbaalenii_PYR-1       RDNG---DGTYTIDGQKMWLTNGGSSTLVAALVRTDEGADKPHRNLTAFL
MSMEG_2208|M.smegmatis_MC2_155      RNND---DGTYTIDGQKMWLTNGGSSTLVAALVRTDEGADKPHRNLTAFL
TH_3384|M.thermoresistible__bu      TRNG---DGTYTIDGQKMWLTNGATSTLVAVLVRTDEGADKPHRNLTTFL
MAV_1575|M.avium_104                RRDP---DGGYTIDGQKMWLTNGATSTLIAVLVRTDEGSDKPHRNLTAFL
MMAR_4030|M.marinum_M               TRGA---DGNYTIDGQKMWLTNGGSSTLVAVLVRTDEGAAQPHRNLTAFL
MUL_3895|M.ulcerans_Agy99           TRGA---DGNYTIDGQKMWLTNGGSSTLVAVLVRTDEGAAQPHRNLTAFL
MLBr_00737|M.leprae_Br4923          KADG----DDWILNGFKCWITNGGKSTWYTVMAVTDP--DKGANGISAFI
MAB_1188c|M.abscessus_ATCC_199      IRQG----DEYVLNGVKQFISGAGAADLYVVMARTG---GPGPRGISTIV
                                                ::* * :::..  :   ..:  *.       ..:: .:

Mb0221c|M.bovis_AF2122/97           VEPG-------PGLTVSRDLPKLGYKGVESCELSFDNLRVPVSAILGGAM
Rv0215c|M.tuberculosis_H37Rv        VEPG-------PGLTVSRDLPKLGYKGVESCELSFDNLRVPVSAILGGAM
Mflv_4367|M.gilvum_PYR-GCK          IEKPTGFGEVAPGLTIPGKLDKLGYKGIDTTELIFDGYRADAGDILGEAP
Mvan_1977|M.vanbaalenii_PYR-1       IEKPTGFGEVAPGLTIPGKLDKLGYKGIDTTELIFDGYRAGATDILGEAP
MSMEG_2208|M.smegmatis_MC2_155      IEKPEGFGEVLPGLTIPGKLDKLGYKGIDTTELIFDGYRADAADILGGTP
TH_3384|M.thermoresistible__bu      IEKPTGFGEVAPGLTIPGKIDKLGYKGIDTTELIFDGYRADAGDILGERP
MAV_1575|M.avium_104                VEKPVGFGEVVAGLRIPGKIDKLGYKGIETTELIFDGYRAAADDILGGTP
MMAR_4030|M.marinum_M               VEKPTGFGEVLPGLTIPGKIDKLGYKGIDTTELIFDGYRATADDILGGTP
MUL_3895|M.ulcerans_Agy99           VEKPTGFGEVLPGLTIPGKIDKLGYKGIDTTEVIFDGYRATADDILGGTP
MLBr_00737|M.leprae_Br4923          VHKDD------EGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGE-P
MAB_1188c|M.abscessus_ATCC_199      VPKGT------PGLSFGAPERKMGWHAQPTAQVVFEDVRVPVANRIGE-E
                                    :           *: .     *:* :.  : :: *:  *      :*   

Mb0221c|M.bovis_AF2122/97           GQGFSQMMKGLETGRIQVAARALGVATAALEDSLAYAQQRESFGRPIWQH
Rv0215c|M.tuberculosis_H37Rv        GQGFSQMMKGLETGRIQVAARALGVATAALEDSLAYAQQRESFGRPIWQH
Mflv_4367|M.gilvum_PYR-GCK          GQGFFQMMDGVEVGRVNVSARACGVGIRAFELAVKYAQQRSTFGKPIAEH
Mvan_1977|M.vanbaalenii_PYR-1       GQGFFQMMDGVEVGRVNVSARACGVGIRAFELAVRYAQQRSTFGKPIAEH
MSMEG_2208|M.smegmatis_MC2_155      GQGFFQMMDGVEVGRVNVSARACGVGLRAFELAVRYAQQRETFGKPIAEH
TH_3384|M.thermoresistible__bu      GQGFFQMMDGVEVGRVNVSARACGVGIRAFELAVRYAQQRHTFGKPIAEH
MAV_1575|M.avium_104                GQGFFQMMDGIEVGRVNVSARACGVAIRAFELAVRYAQQRETFGKPIAEH
MMAR_4030|M.marinum_M               GQGFFQMMDGIEVGRVNVSARACGVGLRAFELAVRYAQQRHTFGKPIAEH
MUL_3895|M.ulcerans_Agy99           GQGFFPMMDGIEVGRVNVSARACGVGLRAFELAVRYAQQRHTFGKPIAEH
MLBr_00737|M.leprae_Br4923          GTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTF
MAB_1188c|M.abscessus_ATCC_199      GIGFTIAMRGLNGGRLNIASCSLGGARSALEKVIEYLRTRKAFGEELIKF
                                    * **   :  ::  *  :.: : * .  *::  : * : *  **. :  .

Mb0221c|M.bovis_AF2122/97           QAVGNYLADMATKLTAARQLTRYAAERYDSGQ-RCDMEAGMAKLFASEVA
Rv0215c|M.tuberculosis_H37Rv        QAVGNYLADMATKLTAARQLTRYAAERYDSGQ-RCDMEAGMAKLFASEVA
Mflv_4367|M.gilvum_PYR-GCK          QAIAFQLAEMATKVEAAHLMMVNAARHKDSGE-RNDVAAGMAKYFASEVC
Mvan_1977|M.vanbaalenii_PYR-1       QAIAFQLAEMATKVEAAHLMMVNAARLKDSGE-RNDVAAGMAKYFASEVC
MSMEG_2208|M.smegmatis_MC2_155      QAVAFQLAEMATKVEAAHLMMVNAARLKDSGE-RNDVAAGMAKYLASEFC
TH_3384|M.thermoresistible__bu      QAIAFQLAEMATKVEAAHLMMVNAARLKDSGE-RNDVAAGMAKYLASEFC
MAV_1575|M.avium_104                QAIAFQLAEMATKVEAAHLMMVNAARLKDSGE-RNDVAAGMAKYLASEYC
MMAR_4030|M.marinum_M               QAISFQLAEMATKVEAAHLMMVHAARLKDSGE-RNDVAAGMAKYLASEYC
MUL_3895|M.ulcerans_Agy99           QAISFQLAEMATKVEAAHLMMVHAARLKDSGE-RNDVAAGMAKYLASEYC
MLBr_00737|M.leprae_Br4923          QSIQFMLADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIA
MAB_1188c|M.abscessus_ATCC_199      QALQFRLADMATELEAARTMVWRAAAAVTEGDPRAAELCAMAKRIATDVG
                                    *::   **:** :: **: :   **     *:      .. :* :*::  

Mb0221c|M.bovis_AF2122/97           MEIALNAVRIHGGYGYSTEYDVERYFRDAPLMILGEGTNEIQRNVIAGQL
Rv0215c|M.tuberculosis_H37Rv        MEIALNAVRIHGGYGYSTEYDVERR-------------------------
Mflv_4367|M.gilvum_PYR-GCK          AEVTQQSFRIHGGYGYSKEYEIERLMRDAPFLLIGEGTSEIQKNIISKRL
Mvan_1977|M.vanbaalenii_PYR-1       AEVTQQSFRIHGGYGYSKEYEIERLMRDAPFLLIGEGTSEIQKNIISKRL
MSMEG_2208|M.smegmatis_MC2_155      SEVTQQAFRIHGGYGYSKEYEIERLMRDAPFLLIGEGTSEIQKNIISKRL
TH_3384|M.thermoresistible__bu      AEVTEQSFRIHGGYGYSKEYEIERLMRDAPFLLIGEGTSEIQKNIISKRL
MAV_1575|M.avium_104                AEVTQQSFRIHGGYGYSKEYEIERLMRDAPFLLIGEGTSEIQKNIISKRL
MMAR_4030|M.marinum_M               SEVTQQSFRIHGGYGYSKEYEIERLMRDAPFLLIGEGTSEIQKSIISKRL
MUL_3895|M.ulcerans_Agy99           SEVTQQSFRIHGGYGYSKEYEIERLMRDAPFLLIGEGTSEIQKSIISKRL
MLBr_00737|M.leprae_Br4923          MEVTTDAVQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRAL
MAB_1188c|M.abscessus_ATCC_199      FTVANEALQLHGGYGYLAEYGIEKIVRDLRVHQILEGTNEIMRVIVSRKL
                                      :: ::.::.** **  :: :*:                          

Mb0221c|M.bovis_AF2122/97           VARGGI-
Rv0215c|M.tuberculosis_H37Rv        -------
Mflv_4367|M.gilvum_PYR-GCK          LADYRV-
Mvan_1977|M.vanbaalenii_PYR-1       LADYRV-
MSMEG_2208|M.smegmatis_MC2_155      LADYKV-
TH_3384|M.thermoresistible__bu      LADYRI-
MAV_1575|M.avium_104                LAEYRV-
MMAR_4030|M.marinum_M               LHEYRE-
MUL_3895|M.ulcerans_Agy99           LHEYRE-
MLBr_00737|M.leprae_Br4923          LR-----
MAB_1188c|M.abscessus_ATCC_199      IEQGLPA

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_3384	-	-	100% (398)	acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)	TH_3837	-	e-100	46.88% (384)	PUTATIVE Butyryl-CoA dehydrogenase
M. thermoresistible (build 8)	TH_4603	-	2e-67	36.17% (376)	PUTATIVE acyl-CoA dehydrogenase domain protein