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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3200 | - | - | 100% (415) | amidohydrolase |
| M. thermoresistible (build 8) | TH_0262 | - | 4e-48 | 33.89% (419) | amidohydrolase |
| M. thermoresistible (build 8) | TH_2020 | - | 1e-43 | 35.02% (414) | amidohydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0076 | - | 2e-24 | 28.37% (363) | hypothetical protein Mb0076 |
| M. gilvum PYR-GCK | Mflv_2466 | - | 1e-48 | 35.75% (400) | amidohydrolase |
| M. tuberculosis H37Rv | Rv0074 | - | 2e-24 | 28.37% (363) | hypothetical protein Rv0074 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3236c | - | 3e-16 | 26.22% (370) | amidohydrolase |
| M. marinum M | MMAR_4746 | - | 9e-45 | 36.06% (416) | imidazolonepropionase |
| M. avium 104 | MAV_0903 | - | 6e-46 | 36.18% (398) | Xaa-Pro dipeptidase |
| M. smegmatis MC2 155 | MSMEG_0297 | - | 1e-46 | 33.73% (421) | amidohydrolase |
| M. ulcerans Agy99 | MUL_0705 | - | 4e-36 | 31.48% (413) | imidazolonepropionase |
| M. vanbaalenii PYR-1 | Mvan_4188 | - | 1e-48 | 35.10% (396) | amidohydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0076|M.bovis_AF2122/97 MGDLSISQVSARPGRIGIRARQMFDGYR-FQRGPVLVVVEDGRISAVDFA
Rv0074|M.tuberculosis_H37Rv MGDLSISQVSARPGRIGIRARQMFDGYR-FQRGPVLVVVEDGRISAVDFA
Mflv_2466|M.gilvum_PYR-GCK ------------MTVTVVKAARWADVEAGVVRSPAVIVVEGNRIRSVDPA
Mvan_4188|M.vanbaalenii_PYR-1 ------------MTGTVLKAARWADVEAGVVRAPAVIVVEGNRIQAINPA
MSMEG_0297|M.smegmatis_MC2_155 ------------MTQTVLRAARWVDVAAGVVRAPAVVVIEGNRITEVNPA
MMAR_4746|M.marinum_M --------------MLTLKAAGLLDVDAGEILAPAVVRVEGDRIAGVGGD
MAV_0903|M.avium_104 --------------MQTIKAAGLFDVDAGEIVRPGLLRVDGDRIVGVGDS
MUL_0705|M.ulcerans_Agy99 ----------MEPNELHISNVKVFDSVDGRITGPVDVTVRGPVIASIAPA
TH_3200|M.thermoresistible__bu -----------VVSKLLLHNALLIDGTGVPPVRDAAVLIDDGRIGWAGPG
MAB_3236c|M.abscessus_ATCC_199 -------------------MRAHLRGRTLPSEEPIDLWVHDGVISIEPIA
: : . *
Mb0076|M.bovis_AF2122/97 G---SACPDMNLVDLGESTLLPGLVDAHAHLCWDPDGRPEDLAG------
Rv0074|M.tuberculosis_H37Rv G---SACPDMNLVDLGESTLLPGLVDAHAHLCWDPDGRPEDLAG------
Mflv_2466|M.gilvum_PYR-GCK A---EPPG-AEVLDLGDVTLLPGLMDMELNLLIGGPGGPEGLPSPMHGVQ
Mvan_4188|M.vanbaalenii_PYR-1 G---EPADSPTVIDLGDVTLLPGLMDMELNLLIGGPGGPEGLPSPMHGVQ
MSMEG_0297|M.smegmatis_MC2_155 A---PLPDTAAVIDLGDVTLLPGLMDMELNLLIG---GPEGLPSPMHGVQ
MMAR_4746|M.marinum_M -------PEGDVIDLGDQILLPGLMDMEVNLLMGGRGEKPGLS----QVQ
MAV_0903|M.avium_104 G---PTGADDNVIDLGEAILLPGLMDMEVNLLMGGRGEKPGLS----QVQ
MUL_0705|M.ulcerans_Agy99 G---AAALSGPAIDGTGKTLLPGLIDAHWHAMFTTIPAALAQVS------
TH_3200|M.thermoresistible__bu DDIPPSADGATRIDVGGNAVCPGFFDCHVHFSLPGTRGSVYER-----AL
MAB_3236c|M.abscessus_ATCC_199 D---------ADTVFDGGWLLPGLVDAHCHVGIGP---------------
: **:.* . :
Mb0076|M.bovis_AF2122/97 DPHAVLVGRARRHAAAALRSGITTIRDLGDRDYAA-----LALREEYRQK
Rv0074|M.tuberculosis_H37Rv DPHAVLVGRARRHAAAALRSGITTIRDLGDRDYAA-----LALREEYRQK
Mflv_2466|M.gilvum_PYR-GCK DDPAYRTLRGAVNARTTLDAGFTTVRNLGLMVKTGGYLLDVALQRAIEQG
Mvan_4188|M.vanbaalenii_PYR-1 DDPAYRTLRGAVNARTTLDAGFTTVRNLGLMVKTGGYLLDVALQRAIEQG
MSMEG_0297|M.smegmatis_MC2_155 DDPAYRTLRGAVNARTTVQAGFTTVRNLGLMVKTGGYLLDVALQRAIDQG
MMAR_4746|M.marinum_M DDPPTRMLRAVGNARRTLRAGFTTVRNLGLFVKTGGYLLDVALGKAIDAG
MAV_0903|M.avium_104 DDPPTRVLRAVGNARRTLRAGFTTVRNLGLFVKTGGYLLDVALAKAIDAG
MUL_0705|M.ulcerans_Agy99 -EFGYVVARAVVSARETLLRGFTTVRDLGGPVFG--------VKQAIDEG
TH_3200|M.thermoresistible__bu VTESYHTFQLLDRLKVTLENGVTTARDLMGIDTG--------VRQAVADG
MAB_3236c|M.abscessus_ATCC_199 -QGPTSLEEAVAQAEAEREVGALLLRDAGSPVDTRG-----------FDE
. * *:
Mb0076|M.bovis_AF2122/97 TTVGPELVVSGPPLTRSGGHCWFLG---------------------GVAD
Rv0074|M.tuberculosis_H37Rv TTVGPELVVSGPPLTRSGGHCWFLG---------------------GVAD
Mflv_2466|M.gilvum_PYR-GCK WHPGPRIYPAGHAVTPYGGHLDPTVFQRLAP------GIMPLSVAEGIAN
Mvan_4188|M.vanbaalenii_PYR-1 WHVGPRIFPAGHAVTPYGGHLDPTVFQRLAP------GIMPLSVAEGIAN
MSMEG_0297|M.smegmatis_MC2_155 WHQGPRIHPAGHAVTPYGGHLDPTVFQRLAP------GIMPLSVAEGIAN
MMAR_4746|M.marinum_M WIDGPRIVPAGHAITPTGGHLDPTMFAAFAP------HVLELTIEEGIAN
MAV_0903|M.avium_104 WIDGPRVVPAGHAITPTGGHLDPTMFAAFAP------HALELTVEEGIAN
MUL_0705|M.ulcerans_Agy99 SIPGPRIYPAGGFISQSGGHGDFRLPNEVPRGVCGHLSYTEIIGAAVIAD
TH_3200|M.thermoresistible__bu LIPGPRLQVAVNMLSQTAGHADFRLPSGIDA---------TAMMGGARVD
MAB_3236c|M.abscessus_ATCC_199 REDLPRIIRAGRHLAKPKRYIPGLP---------------------LDIE
*.: : :: : :
Mb0076|M.bovis_AF2122/97 SVEELVDAVQERAARGADWIKVMATGGFVTTASDPWQPQYGSGQLAAVVA
Rv0074|M.tuberculosis_H37Rv SVEELVDAVQERAARGADWIKVMATGGFVTTASDPWQPQYGSGQLAAVVA
Mflv_2466|M.gilvum_PYR-GCK GVDDVRACVRYQVRHGAKLIKVSASGGVMSHSTAPGAQQYSDEEFAAIAD
Mvan_4188|M.vanbaalenii_PYR-1 GVDDVRACVRYQIRHGAKLIKVSASGGVMSHSTAPGAQQYSDEEFAAIAD
MSMEG_0297|M.smegmatis_MC2_155 GVPDVIACVRYQIRHGARLIKVSASGGVMSHSTAPGAQQYGDAELAAIAD
MMAR_4746|M.marinum_M GVDEIRKAVRYQIKHGAQLIKVCCSGGVMSLTGPPGAQHYSDEELRAIVD
MAV_0903|M.avium_104 GIDEIRKAVRYQIKHGAELIKVCCSGGIMSLTGPPGAQHYSDEELRAIVD
MUL_0705|M.ulcerans_Agy99 GEAEVLRGAREMLRRGASQLKLMAGGGVTSAYDPLDVAQFTETEMRAAVE
TH_3200|M.thermoresistible__bu SVDDVRRRVRDLIAQGADLIKVASSGGVSSPTDQPDWLGMRTEMVAAVVE
MAB_3236c|M.abscessus_ATCC_199 DDAQLPEAVALQARWGDGWVKLVG--DWIDRAVGDLAPLWSDKILKQAID
. :: . * :*: . .
Mb0076|M.bovis_AF2122/97 AAEQVGLP-VTAHAHATAGIAAAVAAGVDGIEHCTFLSEGSAAASPDVVE
Rv0074|M.tuberculosis_H37Rv AAEQVGLP-VTAHAHATAGIAAAVAAGVDGIEHCTFLSEGSAAASPDVVE
Mflv_2466|M.gilvum_PYR-GCK EAHRAGVR-VAAHAVGDSAIRACIRAGIDCIEHGFLATDETLQMMVDHGT
Mvan_4188|M.vanbaalenii_PYR-1 EAHRAGVR-VAAHAVGDSAIRACIRAGIDCIEHGFLASDETIQMMADHGT
MSMEG_0297|M.smegmatis_MC2_155 EAHRAGVK-VAAHAVGDTAIQACIRAGIDCIEHGFLATDETIQMMVDHGT
MMAR_4746|M.marinum_M EAHRRGLR-VAAHTHGADAVKHAVIAGIDCIEHGFLVDDEAIAMMVEHGT
MAV_0903|M.avium_104 EAHRRGMR-VAAHTHGADAVKHAVAAGIDCIEHGFLIDDEAIASMVEHGT
MUL_0705|M.ulcerans_Agy99 AAENWGTY-VTVHAYTPRAIRAAIAAGVRCVEHGQLIDEPTAALLAEKDI
TH_3200|M.thermoresistible__bu ECQAYGGRPVAAHAIGYAGVKAAVEGGVTSIEHGYALDDELRRRMVDQGT
MAB_3236c|M.abscessus_ATCC_199 AAHANGAR-VTAHVFGEDALPGLIHAGIDCIEHGTGLTDDTIALMVEHGT
.. * *:.*. .: : .*: :** : :
Mb0076|M.bovis_AF2122/97 AIVAQGVWCGMT-----IPRVYPEMPENLVAVVQDGWRNIRRLIDAGARV
Rv0074|M.tuberculosis_H37Rv AIVAQGVWCGMT-----IPRVYPEMPENLVAVVQDGWRNIRRLIDAGARV
Mflv_2466|M.gilvum_PYR-GCK FLVSTTYLTEA----MAVDRIAPELRKKAEVVFPQAQAMLPKAIAAGVRI
Mvan_4188|M.vanbaalenii_PYR-1 FLVSTTYLTEA----MAIDRIAPELRKKAEVVFPQAQAMLPKAIAAGVRI
MSMEG_0297|M.smegmatis_MC2_155 FLVSTTYLTDA----MAIDRIAPELRKKALDVFPRAKAMLPKAIAAGVRI
MMAR_4746|M.marinum_M FLVSTRRLADADA--MDISHAPPELQAKAAEMFPRSRESILAAYQAGVKI
MAV_0903|M.avium_104 FLVSTRRLAEG----MDVSHAPPELQAKAAQMFPKSRTSILAAHRAGVKI
MUL_0705|M.ulcerans_Agy99 WWCLQPFLDDE-----DAVAVPPPSVPKFKQMVAGTDTAYQLAIKHGVKI
TH_3200|M.thermoresistible__bu YLVPTLLETMH------DVEVSPAAKAKSAHWHEIAHRAVGESAAAGVKI
MAB_3236c|M.abscessus_ATCC_199 ALVPTVINIENFPGIADKAGKYPKYAQHMRDLYAGLHTTFGNAYDAGIPI
* : * :
Mb0076|M.bovis_AF2122/97 ALSTDAGVAPGRRHDVLPDDLVYLSRHGFTSTEVLTGATAAAAASCGLG-
Rv0074|M.tuberculosis_H37Rv ALSTDAGVAPGRRHDVLPDDLVYLSRHGFTSTEVLTGATAAAAASCGLG-
Mflv_2466|M.gilvum_PYR-GCK ACGTDAPAVP-HGQN-AKELCALVSRG-MTPMQALRAATITSAELIDA--
Mvan_4188|M.vanbaalenii_PYR-1 ACGTDAPAIP-HGQN-AKELRALVSRG-MSPMQALRAATMTAAELIEA--
MSMEG_0297|M.smegmatis_MC2_155 ACGTDAPAIP-HGQN-AKELCALVERG-MTPMQALQAATVVAAELVDA--
MMAR_4746|M.marinum_M AIGTDAPAIP-HGRN-ADELVTLVHWG-MSPMAVLRAATVTAAELINV--
MAV_0903|M.avium_104 AVGTDAPAIP-HGRN-ADELVTLVEWG-LPPVAVLRAATVTAAELINS--
MUL_0705|M.ulcerans_Agy99 AFGTDTLFDA-KLASRQGAQLAKLTRW-FTPAEVLQQATIRNAELLAMSG
TH_3200|M.thermoresistible__bu ALGTDAGLSP-DHGTNLAELGLLVRFGGLTPMEAIVAGTRTSAQLCGL--
MAB_3236c|M.abscessus_ATCC_199 YAGTDAGGSI--AHGRISDEVAALTRIGMSPTDALGAASWRARSWLGRP-
.**: : :.. .: .:
Mb0076|M.bovis_AF2122/97 ------HRKGRIAPGYDADLLAVAAGVDHDPAGLCDVK----AVWRSGTQ
Rv0074|M.tuberculosis_H37Rv ------HRKGRIAPGYDADLLAVAAGVDHDPAGLCDVK----AVWRSGTQ
Mflv_2466|M.gilvum_PYR-GCK -----EDELGRLAPGYLADIIAVDGDVSADIATTLDVR----FVMKDGVV
Mvan_4188|M.vanbaalenii_PYR-1 -----DDELGRLAPGYLADIIAVAGDPSNDIATTLDVR----FVMKDGVV
MSMEG_0297|M.smegmatis_MC2_155 -----SDELGRLAPGYLADVVAVPGDPSTDISAILDVS----FVMKDGAV
MMAR_4746|M.marinum_M -----TDR-GRLAAGQLADIIAVAGNPLDDITVTRNVG----FVMKGGKV
MAV_0903|M.avium_104 -----SDR-GRLAEGYLADVIAVPGNPLEDITVTQHVS----FVMKGGKV
MUL_0705|M.ulcerans_Agy99 PRNPYPGRLGVVAEGALADLILVDGDPIADISLIARPDETFTTIIKNGRV
TH_3200|M.thermoresistible__bu -----DRELGTLEPGKLADVVVVRGNPLDDIASVGNPD-NILLVLKEGRP
MAB_3236c|M.abscessus_ATCC_199 ----------GLEHGAPADLLGYRADPRTGPGVLASPD----LVMLRGQI
: * **:: .. . : *
Mb0076|M.bovis_AF2122/97 VPLQASAVGYNTPS-
Rv0074|M.tuberculosis_H37Rv VPLQASAVGYNTPS-
Mflv_2466|M.gilvum_PYR-GCK HKTVDVAQDASTSTV
Mvan_4188|M.vanbaalenii_PYR-1 HKGAEGGGREG----
MSMEG_0297|M.smegmatis_MC2_155 VKHREPSDAAVR---
MMAR_4746|M.marinum_M YVHQD----------
MAV_0903|M.avium_104 YVHNQN---------
MUL_0705|M.ulcerans_Agy99 VKGAAS---------
TH_3200|M.thermoresistible__bu AKDRGGFFDQRH---
MAB_3236c|M.abscessus_ATCC_199 R--------------