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M. thermoresistible (build 8) TH_3177 (-)

annotation: putative ABC transporter integral membrane subunit
coordinates: 4535823 - 4536605
length: 261

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3177--100% (261)putative ABC transporter integral membrane subunit

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1660-3e-0728.57% (168) drug efflux membrane protein
M. gilvum PYR-GCKMflv_0192-3e-7355.82% (249) putative ABC transporter membrane protein
M. tuberculosis H37RvRv1634-3e-0728.57% (168) drug efflux membrane protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4214c-5e-5345.60% (250) ABC transporter
M. marinum MMMAR_2438-6e-0523.46% (179) drug efflux membrane protein
M. avium 104MAV_3140-2e-0523.16% (190) drug efflux membrane protein
M. smegmatis MC2 155MSMEG_0796-2e-8058.06% (248) ABC transporter integral membrane subunit
M. ulcerans Agy99MUL_1617-6e-0624.02% (179) drug efflux membrane protein
M. vanbaalenii PYR-1Mvan_0713-3e-7254.94% (253) putative ABC transporter membrane protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0192|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0713|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0796|M.smegmatis_MC2_155      --------------------------------------------------
TH_3177|M.thermoresistible__bu      --------------------------------------------------
MAB_4214c|M.abscessus_ATCC_199      --------------------------------------------------
Mb1660|M.bovis_AF2122/97            MTETASETGSWRELLSR-YLGTSIVLAGGVALYATNEFLTISLLPSTIAD
Rv1634|M.tuberculosis_H37Rv         MTETASETGSWRELLSR-YLGTSIVLAGGVALYATNEFLTISLLPSTIAD
MMAR_2438|M.marinum_M               MTETARETGSWRELLSG-HLGTATLLAGGVAMYATNEFLTVSLLPSTIAE
MUL_1617|M.ulcerans_Agy99           MTETARETGSWRELLRG-HLGTATLLAGGVAMYATNEFLTVSLLPSTIAE
MAV_3140|M.avium_104                MTDAATITGGWRELLGARYLRTSILLAGGVALYATNEFLTTSLLPNTIAE
                                                                                      

Mflv_0192|M.gilvum_PYR-GCK          -----------MIRTAARAVDAERIKLLTLRSPLWAAAAAAVLSFALAAL
Mvan_0713|M.vanbaalenii_PYR-1       -----------MMATAGAVLNAERIKLTTLRSPLWATVAAAVLSFGLSAL
MSMEG_0796|M.smegmatis_MC2_155      -------------MSALAALDAERIKLSTTRSPLWSVVGAAVLSFAIAAL
TH_3177|M.thermoresistible__bu      -----VSAVMSMATGLAAAVNAERVKLLTTRAPLWSALGVAVSALGVAAL
MAB_4214c|M.abscessus_ATCC_199      ----------------MGVVAAERIKVCTSRSAVWCSLLALALGVGLAGL
Mb1660|M.bovis_AF2122/97            IGGSRLYAWVTTLYLVGSVVAATTVNTMLLRVGARSSYLMGLAVFGLASL
Rv1634|M.tuberculosis_H37Rv         IGGSRLYAWVTTLYLVGSVVAATTVNTMLLRVGARSSYLMGLAVFGLASL
MMAR_2438|M.marinum_M               IGGSRLYAWVTTLYLVGSVVSATTVNAMLLKVGARMSYLMGLTVFGFASL
MUL_1617|M.ulcerans_Agy99           IGGSRLYAWVTTLYLVGSVVSATTVNAMLLKVGARMSYLMGLTVFGFASL
MAV_3140|M.avium_104                IGGSRLYAWVTTLYLVGSVVAATMVNPMLLRVGARASYLLGLAVFGVASL
                                                      .: *  ::    :             ...:.*

Mflv_0192|M.gilvum_PYR-GCK          QASVSYGYAAMPVSTAAMGVA---VFGVPVLMVVAAMTVTGEYRSGLIAT
Mvan_0713|M.vanbaalenii_PYR-1       QASVAYDYARLTVPDAALGVA---VFGVPVLMVVSAMTVTGEYRSGLIAT
MSMEG_0796|M.smegmatis_MC2_155      QGWSAYGYTPLPPGKAALGVA---VFGVPVLMVLASMTMTGEYRTGLIRT
TH_3177|M.thermoresistible__bu      QGLTAHHYSALPPQQAALGVV---VFGIPVLMILAALTVTGEHRTGAIRT
MAB_4214c|M.abscessus_ATCC_199      QGGSASIYAPISPGDAAGGAA---LVGVPLLMVLAAMTVTNENRTAMVRT
Mb1660|M.bovis_AF2122/97            VCAAAPSMQILVAGRTLQGIAGGLLAGLGYALINSTLPKSLWTRGSALVS
Rv1634|M.tuberculosis_H37Rv         VCAAAPSMQILVAGRTLQGIAGGLLAGLGYALINSTLPKSLWTRGSALVS
MMAR_2438|M.marinum_M               VCAAAQNMEMLVAGRTLQGVAGGLLAGLGYALINAALPHNLWTRGSALVS
MUL_1617|M.ulcerans_Agy99           VCAAAQNMEMLVAGRTLQGVAGGLLAGLGYALINAALPHNLWTCGSALVS
MAV_3140|M.avium_104                VCGAAPDMHVLIAGRAMQGVAGGLLAGLGYAVINSALPRWLWTRGSALVS
                                        :     :    :  * .   : *:   :: :::.       . : :

Mflv_0192|M.gilvum_PYR-GCK          TFTAIPRRT---------------LVVCAKAVVAAAFSVVASAVMVFG--
Mvan_0713|M.vanbaalenii_PYR-1       TFMATPHRT---------------LVFCAKALVAAVFSALSAAVMVVG--
MSMEG_0796|M.smegmatis_MC2_155      TFMATPNRS---------------VVLAAKAIVCAAFSSVAAIVMVLG--
TH_3177|M.thermoresistible__bu      TFLAVPRRT---------------VAIAAKTVVATVFCGGWAALMTVA--
MAB_4214c|M.abscessus_ATCC_199      TFQATPNRL---------------TVIGAKALVAGGWVAVVTAVTALT--
Mb1660|M.bovis_AF2122/97            AMWGVATLIGPATGGLFAQLGLWRWAFGVMTLLTALMAMLVPVALGAGRV
Rv1634|M.tuberculosis_H37Rv         AMWGVATLIGPATGGLFAQLGLWRWAFGVMTLLTALMAMLVPVALGAGGV
MMAR_2438|M.marinum_M               AMWGVATLIGPATGGLFAQFGLWRWAFGVMATMAGLMTLLVLVVLSNG-V
MUL_1617|M.ulcerans_Agy99           AMWGVATLIGPATGGLFAQFGLWRWAFGVMATMAGLMTLLVLVVLSNG-V
MAV_3140|M.avium_104                AMWGVATVVGPATGGLFAQLGIWRWAFVVMAVLTALMALLVPVALARV--
                                    :: . .                   .. . : :                 

Mflv_0192|M.gilvum_PYR-GCK          -----------------SVMVARAAAAPGVAAGLTVS--ATMRFAAAIAV
Mvan_0713|M.vanbaalenii_PYR-1       -----------------SVLVARLVADPGVGDALTPA--ATAGFVAAIAL
MSMEG_0796|M.smegmatis_MC2_155      -----------------AVLVARLFTDPLIAVDLSPTNPATWQVAGSFAL
TH_3177|M.thermoresistible__bu      -----------------AILAAGASADPMAAAHLTPTGAAGWRVIAGVTA
MAB_4214c|M.abscessus_ATCC_199      -----------------SMALVRAMAGPVAGANLALDSTGVWNTVGAVTV
Mb1660|M.bovis_AF2122/97            GPGGETPVGSTHKVPVWSLLLMGAAALAISVAALPNYLVQTAGLLAAAAL
Rv1634|M.tuberculosis_H37Rv         GPGGETPVGSTHKVPVWSLLLMGAAALAISVAALPNYLVQTAGLLAAAAL
MMAR_2438|M.marinum_M               AVGGEKPVAPAHKVPVWSLLLMGAAALAVSVAEIPQYLVATAGLLVAGAL
MUL_1617|M.ulcerans_Agy99           AVGGEKPAAPAHKVPVWSLLLMGAAALAVSVAEIPQYLVATAGLLVAGAL
MAV_3140|M.avium_104                ---DPAPAIPRMKVPVWSLLIIGVASLAVSVAQIPHNTAATFGLLAAGIM
                                                     ::      : .     :.           .   

Mflv_0192|M.gilvum_PYR-GCK          YAALTAVLGVGVAVLLRHTAGAVTVLLLWP-------LLIEPLLGNLPGR
Mvan_0713|M.vanbaalenii_PYR-1       YAAPAAVLGVGVATLLRHTAGAVTVLLLWP-------LLIEPLLANLPGR
MSMEG_0796|M.smegmatis_MC2_155      YAALAAILGVAVGALVRFSAGAVAVLLLWP-------LVAEPLLANMPGN
TH_3177|M.thermoresistible__bu      FAMLAAVLGVAVGVLLRNTAGAVAVLLLWP-------LVAEPILANMPDV
MAB_4214c|M.abscessus_ATCC_199      YAFLCAVLAVAVGVLLKHTAGAVAVLLLWP-------TVLELMLGWLTDA
Mb1660|M.bovis_AF2122/97            LVAVFVVVDWRIHAAVLPPSVFGSGPLKWIYLTMSVQMIAAMVDTYVPLF
Rv1634|M.tuberculosis_H37Rv         LVAVFVVVDWRIHAAVLPPSVFGSGPLKWIYLTMSVQMIAAMVDTYVPLF
MMAR_2438|M.marinum_M               LVGIFVIVDWRMHVAVLPHSVFGSGPLKWIYLTMSVQMVAAMVTTYVPLF
MUL_1617|M.ulcerans_Agy99           LVGIFVIVDWRMHVAVLPHSVFGSGPLKWIYLTMSVQMVAAMVTTYVPLF
MAV_3140|M.avium_104                LVGLFVIVDWRMHAAILPPSVFSPGPLKWIYLTMGVLMAAAMVNTYVPLF
                                     .   .::   : . :   :   .  * *             :   :.  

Mflv_0192|M.gilvum_PYR-GCK          SVEIGPYLPFANVFR--FLDVQWLFPE-YPMHWGT---LGSLGYFAAVVG
Mvan_0713|M.vanbaalenii_PYR-1       GWQIGPYLPFANMFR--FLDVQWLFPE-FAMHWGG---PGSLGYFTAVVA
MSMEG_0796|M.smegmatis_MC2_155      GAQIGPWLPFVHMYR--FLDVDWLFPS-YAMPWGP---VGSLIYFVVLVV
TH_3177|M.thermoresistible__bu      APVVGPYLPFGNVFR--FLDVRWLYPV-FDTPWGG---LGSLVYFAVVVA
MAB_4214c|M.abscessus_ATCC_199      GKALQPFLPFANGIR--FTGVPWYTSDGVRFVWDA---TGSLIYFATVVV
Mb1660|M.bovis_AF2122/97            GQRLGHLTPVAAGFLGAALAVGWTVGEVASASLNSARVIGHVVAAAPLVM
Rv1634|M.tuberculosis_H37Rv         GQRLGHLTPVAAGFLGAALAVGWTVGEVASASLNSARVIGHVVAAAPLVM
MMAR_2438|M.marinum_M               GQGLGHLTPVAAGFLGAALAFGWTAGEIVSASLTNPRLIGYIIAAAPLVM
MUL_1617|M.ulcerans_Agy99           GQGLGHLTPVAAGLLGAALAFGWTAGEIVSASLTNSRLIGYIIAVAPLVM
MAV_3140|M.avium_104                GQRLAHLTPIAAGFLGAALALGWTVSEIVSASPENPRTVGRVVMVAPLVA
                                    .  :    *.          . *                * :   . :* 

Mflv_0192|M.gilvum_PYR-GCK          VVFAAGLVMVNRRDA-----------------------------------
Mvan_0713|M.vanbaalenii_PYR-1       TVFVAALITVNRRDT-----------------------------------
MSMEG_0796|M.smegmatis_MC2_155      VVFVAAVVALNRRDA-----------------------------------
TH_3177|M.thermoresistible__bu      VVGVAAVVVVNRRDA-----------------------------------
MAB_4214c|M.abscessus_ATCC_199      ITLVAALAVVQRRDV-----------------------------------
Mb1660|M.bovis_AF2122/97            ASGLALGAVTQRADAPVGIIALWALALLIIGTGIGIAWPHLTVRAMDSVA
Rv1634|M.tuberculosis_H37Rv         ASGLALGAVTQRADAPVGIIALWALALLIIGTGIGIAWPHLTVRAMDSVA
MMAR_2438|M.marinum_M               ASGLALGAVTQRADASLPTVALWALALLITGAGIGIAWPHLTVRAMDCVD
MUL_1617|M.ulcerans_Agy99           ASGLALGAVTQRADASLPTVALWALALLITGAGIGIAWPHLTVRAMDCVD
MAV_3140|M.avium_104                ASGLALGAVARHGDGSAWTAALWAVALLVAGTGIGMAWPHLSARAMASVN
                                        *     .: *                                    

Mflv_0192|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0713|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0796|M.smegmatis_MC2_155      --------------------------------------------------
TH_3177|M.thermoresistible__bu      --------------------------------------------------
MAB_4214c|M.abscessus_ATCC_199      --------------------------------------------------
Mb1660|M.bovis_AF2122/97            DPAESSAAAAAINVVQLISGAFGAGLAGVVVNTAKGGEVAAARGLYMAFT
Rv1634|M.tuberculosis_H37Rv         DPAESSAAAAAINVVQLISGAFGAGLAGVVVNTAKGGEVAAARGLYMAFT
MMAR_2438|M.marinum_M               DPAESSSAAAAINIVQLVSAAFGAGLAGVVVNTATGGEVAAARWLYTVFT
MUL_1617|M.ulcerans_Agy99           DPAESSSAAAAINIVQLVSAAFGAGLAGVVVNTATGGEVAAARWLYTVFT
MAV_3140|M.avium_104                DPAEGGAASAAINTVQLTSAAIGAGLAGVVVNTATGGDEMAAHLLFTVFT
                                                                                      

Mflv_0192|M.gilvum_PYR-GCK          ---------------------------
Mvan_0713|M.vanbaalenii_PYR-1       ---------------------------
MSMEG_0796|M.smegmatis_MC2_155      ---------------------------
TH_3177|M.thermoresistible__bu      ---------------------------
MAB_4214c|M.abscessus_ATCC_199      ---------------------------
Mb1660|M.bovis_AF2122/97            VLAAAGVIASYQATHRDRRLPR-----
Rv1634|M.tuberculosis_H37Rv         VLAAAGVIASYQATHRDRRLPR-----
MMAR_2438|M.marinum_M               VLAAVGFIASYQATHHDRRSPG-----
MUL_1617|M.ulcerans_Agy99           VLAAVGFIASYQATHHDRRSPG-----
MAV_3140|M.avium_104                ALSAAGVAVSYAATRATRQAQPVGNVG