For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2994 | - | - | 100% (65) | dehydrogenase |
| M. thermoresistible (build 8) | TH_4571 | - | 5e-18 | 68.42% (57) | PUTATIVE dehydrogenase |
| M. thermoresistible (build 8) | TH_2036 | - | 4e-07 | 44.44% (54) | POSSIBLE ALANINE RICH DEHYDROGENASE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1467 | - | 8e-14 | 53.57% (56) | dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4235 | - | 3e-06 | 40.74% (54) | hypothetical protein Mflv_4235 |
| M. tuberculosis H37Rv | Rv1432 | - | 8e-14 | 53.57% (56) | dehydrogenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4734 | - | 8e-23 | 78.57% (56) | dehydrogenase |
| M. marinum M | MMAR_1580 | - | 1e-21 | 75.44% (57) | dehydrogenase |
| M. avium 104 | MAV_3342 | - | 2e-13 | 53.57% (56) | dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_2377 | - | 8e-07 | 42.11% (57) | P49 protein |
| M. ulcerans Agy99 | MUL_1826 | - | 2e-13 | 53.57% (56) | dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_2127 | - | 5e-07 | 41.82% (55) | hypothetical protein Mvan_2127 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1467|M.bovis_AF2122/97 -----MTTAVVVGAGPNGLAAAIHLARHGVDVQVLEARDTIGGGARSG-E
Rv1432|M.tuberculosis_H37Rv -----MTTAVVVGAGPNGLAAAIHLARHGVDVQVLEARDTIGGGARSG-E
MUL_1826|M.ulcerans_Agy99 -----MTKAVVVGAGPNGLAAAIQLARHGVEVQVLEAHDTIGGGARSG-E
MAV_3342|M.avium_104 ---------MVVGAGPNGLAAAIQLARRGVEVQVLEAGETPGGGARSS-E
TH_2994|M.thermoresistible__bu --------------------------------------------------
MAB_4734|M.abscessus_ATCC_1997 -----MSTAVIVGGGPNGLTAAILLAQQGVHVTVLEAADSVGGGVRSG-A
MMAR_1580|M.marinum_M -MKGASQTAIVVGGGPNGLAAAITLAKAGLQVTVLEAAEEVGGGARSS-E
Mflv_4235|M.gilvum_PYR-GCK MGSNGQVELTVVGSGPNGLAAAVICARAGVSVRVVEAQPTAGGGARTLPD
Mvan_2127|M.vanbaalenii_PYR-1 MGSNVQVELTVVGSGPNGLAAAVICARAGLSVRVVEAQPTPGGGARTLPD
MSMEG_2377|M.smegmatis_MC2_155 ------MDVTVVGSGPNGLTAAVICARAGLAVRVIEAQTTPGGGARTLPD
Mb1467|M.bovis_AF2122/97 LTVPGVIHDHCSAFHPLGVGSPFWAAIDLQRYGLTWKWPDVDCAHPLDDG
Rv1432|M.tuberculosis_H37Rv LTVPGVIHDHCSAFHPLGVGSPFWAAIDLQRYGLTWKWPDVDCAHPLDDG
MUL_1826|M.ulcerans_Agy99 LTVPGVIHDHCSAFHPLGVGSPFWNEIDLQSYGLTWNWPEVDCAHPLDDG
MAV_3342|M.avium_104 LTVPGVIHDLCSATHPFGVGSPFWKEIDLPSYGLVWKWPQIDCAHPLDDG
TH_2994|M.thermoresistible__bu --------------------------------------------------
MAB_4734|M.abscessus_ATCC_1997 ATGPGLIHDYCSAIHPMAVGSPVLAGLDLEKHGLQWLWPEVDCAHPLDDG
MMAR_1580|M.marinum_M AIVLGLVHDHCSAIHPMAVGSEFLTGLDLDRHGLSWLLPDIDCVHPLDDG
Mflv_4235|M.gilvum_PYR-GCK PEFSGVSHDICSAVHPLALASPFFAAFDLRARGVTLEVPEVSYGNPLPGR
Mvan_2127|M.vanbaalenii_PYR-1 PEFSGVSHDICSAVHPLALASPFFAEFDLQARGVTLAVPEVSYGNPLPGR
MSMEG_2377|M.smegmatis_MC2_155 PEFGGVSHDICSAVHPLALASPFFSAYDLTAHGVRLAVPEIAYANPLVER
Mb1467|M.bovis_AF2122/97 TAGVLYRSIEATAAGLGPDGKRWQRAVGDLAAGFDELAEDLLRPVLNMPR
Rv1432|M.tuberculosis_H37Rv TAGVLYRSIEATAAGLGPDGKRWQRAVGDLAAGFDELAEDLLRPVLNMPR
MUL_1826|M.ulcerans_Agy99 TAGVLHQSIERTAAGMGPDGKRWRCAVGDLAAGFDELAGDLLRPVLGVPR
MAV_3342|M.avium_104 SAGVLYRSIEQTTAGMGPDATRWRRAVGDLAAGFDQLASDLMRPVLRVPH
TH_2994|M.thermoresistible__bu --------------------------------------------------
MAB_4734|M.abscessus_ATCC_1997 SCGVLYRDVAATANGLGRDGRRWRALFERPARNFDLLTADIMGPLLRIPR
MMAR_1580|M.marinum_M SAGVLHRSVGQTADGLGADGRRWRALFDWTSQRFDMLAEDIMGPLLSIPG
Mflv_4235|M.gilvum_PYR-GCK RAAIGYLDIDRTCAELE-DGEPWRRLLGPLAADCDGVVGLLLGDKRSIPP
Mvan_2127|M.vanbaalenii_PYR-1 PAAVGYRDIERTCAELD-DGASWRRLLGPLADDCDGVVGLLLGDKRSIPP
MSMEG_2377|M.smegmatis_MC2_155 PAAIGYRDIDRTCAELD-DGRSWRRLLGPLADDCDGVVGLMLGDKRSLPP
Mb1467|M.bovis_AF2122/97 HPIRLARFGPRAALPATAMARRFHTERARALFGGAAAHVYTRLDRPLTAS
Rv1432|M.tuberculosis_H37Rv HPIRLARFGPRAALPATAMARRFHTERARALFGGAAAHVYTRLDRPLTAS
MUL_1826|M.ulcerans_Agy99 HPLRPAAFGPRAALPATMMARWFRTEQARALFGGAAAHVYTRLDRPLTAS
MAV_3342|M.avium_104 HPVRLARFGPRALLPATVLARWFHTEQARALFGGAAAHIYTRLDRPLTAS
TH_2994|M.thermoresistible__bu --------------------------------------------------
MAB_4734|M.abscessus_ATCC_1997 HPLALTRFGVPTVLPAAATAQLFRTRQARALFGGIAAHAFRPLHYPMTSA
MMAR_1580|M.marinum_M HPITLARFGVPTVLPASVLARLFRTDQGRALFGGVAAHAFRPLHYPMTSA
Mflv_4235|M.gilvum_PYR-GCK SIPAALRVAPRLLAQGTPAWGTLLGEDARALFTGVAAHTISRMPSLVASG
Mvan_2127|M.vanbaalenii_PYR-1 SIPAAVRVAPRLLAQGSPAWGTLAGEDARALFTGVAAHTISRMPSLVSAG
MSMEG_2377|M.smegmatis_MC2_155 SIPAALRVAPRMLGQGTALWRLLRGDDARALFSGVAAHTISPMPSLVSAG
Mb1467|M.bovis_AF2122/97 LGLMILASGHRHGWPVARGGSGSITKALAAALDAYGGTVATGVTVTSRRD
Rv1432|M.tuberculosis_H37Rv LGLMILASGHRHGWPVARGGSGSITKALAAALDAYGGTVATGVTVTSRRD
MUL_1826|M.ulcerans_Agy99 LGLMILASGHRYGWPVAQGGSGSITAALGAALDALGGVVATGITVTSRRD
MAV_3342|M.avium_104 LGLLFLASGHRYGWPVAEGGSGSIIHALVAALRAHGGDVATGVTVSDRRD
TH_2994|M.thermoresistible__bu --------------------------------------------------
MAB_4734|M.abscessus_ATCC_1997 IGLGIITAGHRHGWPVAAGGSQSITDALSSLLAQFGGRIETGVHVTSFTQ
MMAR_1580|M.marinum_M IGLGIITAGHRHGWPVAAGGSQSITNALVATLDELGGKIETGVRVQTASQ
Mflv_4235|M.gilvum_PYR-GCK AGLMLSTLAHAVGWPIPVGGSQAIPDALIADLRAHGGELVVGEEVST---
Mvan_2127|M.vanbaalenii_PYR-1 AGLMLATLGHTVGWPVPSGGSQAIPDALLADLQAHGGELVLGEEVTS---
MSMEG_2377|M.smegmatis_MC2_155 AGLMLATLAHAVGWPIPIGGSQAIPDALIADLRAHGGELVLGEEVTE---
Mb1467|M.bovis_AF2122/97 IPDADIVMLDLSPAAVLGIYGDVMPTRINRSYRRYRAGSSAFKVDFAIEG
Rv1432|M.tuberculosis_H37Rv IPDADIVMLDLSPAAVLGIYGDVMPTRINRSYRRYRAGSSAFKVDFAIEG
MUL_1826|M.ulcerans_Agy99 IPDADIVMLDLSPANVLTLYGDEMPARIKRSYRRYREGSSAFKVDFAIEG
MAV_3342|M.avium_104 IPDADIVMLDLTPAAALRLYGELMPARIARSYRRYRQGSSAFKVDFAVEG
TH_2994|M.thermoresistible__bu --------------------------------------------------
MAB_4734|M.abscessus_ATCC_1997 LPTADVTLFDLSPTQVADILRDHLPTSVARGLSRFRYGPGAFKVDFAIED
MMAR_1580|M.marinum_M LPPADVTMFDLAPDAVAGILGDRMPGRIARAYNKFRRGPGAFKVDFAIEG
Mflv_4235|M.gilvum_PYR-GCK -PPSGVVLYDTAPTALLDIYGDRLPSRYARTLRRYRYGPGVAKVDFVLSG
Mvan_2127|M.vanbaalenii_PYR-1 -PPSGVVLYDTAPTALLRIYGDRLPPGYAKTLRRYRYGPGVAKVDFVLSG
MSMEG_2377|M.smegmatis_MC2_155 -PPSGVVVYDTAPTALLSIYRDAVPPRYAKALRNYTYGSGVAKVDFVLSG
Mb1467|M.bovis_AF2122/97 DVGWTNPDCRRAGTVHLGGTFAEIADTERQRAQGTMVQRPFVLVGQQYLA
Rv1432|M.tuberculosis_H37Rv DVGWTNPDCRRAGTVHLGGTFAEIADTERQRAQGTMVQRPFVLVGQQYLA
MUL_1826|M.ulcerans_Agy99 DIPWTNPDCRRAGTVHLGGTFAEIADTERQRAQGRMVQRPFVLIGQQYLA
MAV_3342|M.avium_104 DIPWTNPHCARAGSVHLGGSFAEIADTERQRAQGKLAPRPFVLVGQQYLA
TH_2994|M.thermoresistible__bu ------------------------------------------------LA
MAB_4734|M.abscessus_ATCC_1997 GVPWTNPDAGRAGTVHLGGTFAEVASTERAVHAGRMPERPFVLVGQQYLA
MMAR_1580|M.marinum_M AVPWTNPQARRAGTVHLGGPYAELAAAEREVHAGRMPQRPFVLVGQQYLA
Mflv_4235|M.gilvum_PYR-GCK EIPWRDKRLASAPTLHMGGDRATMALAEKDIAEGRHAQWPMVLASLPHLA
Mvan_2127|M.vanbaalenii_PYR-1 EIPWRDPRLANAPTLHLGGDRATMARAEKDVAAGRHAEWPMVLASLPHLA
MSMEG_2377|M.smegmatis_MC2_155 EIPWRDPRLAQSPTLHLGGSREQMALAESEVARGRHAEWPMVLAASPHIA
:*
Mb1467|M.bovis_AF2122/97 DPSRSVG-NINPIWAYAHVPFGYTGDATAAVIDQIERFAPGFRDRIVATV
Rv1432|M.tuberculosis_H37Rv DPSRSVG-NINPIWAYAHVPFGYTGDATAAVIDQIERFAPGFRDRIVATV
MUL_1826|M.ulcerans_Agy99 DPSRSAG-NINPIWAYAHVPFGYAGDATAAVIDQIERFAPGFRDRITATV
MAV_3342|M.avium_104 DPSRSAG-GINPIWAYAHVPFGYTGDATALVVDQIERFAPGFRDRVVATV
TH_2994|M.thermoresistible__bu NMRRNS---------------------------QLEWFAPGFRDRVVGMA
MAB_4734|M.abscessus_ATCC_1997 DPGRSNG-NIHPLWTYAHVPHGFTGDATQALIDQIERFAPGFRDRIVATA
MMAR_1580|M.marinum_M DPERSVG-NIHPLWTYAHVPNGYTGDATAAIIAQIERFAPGFREHIVGQT
Mflv_4235|M.gilvum_PYR-GCK DPGRIDAAGRRPLWTYAHVPAGSTVDMAETITGVFERFAPGFRDLVVGVR
Mvan_2127|M.vanbaalenii_PYR-1 DPGRVDPQGRRPLWTYAHVPAGSTVDMAEAVTEVIERFAPGFRDVVVGVR
MSMEG_2377|M.smegmatis_MC2_155 DPGRIDARGRRPLWTYAHVPSGSPVDMADTVTSILERFAPGFRDLVVAVR
: * :* ******: :..
Mb1467|M.bovis_AF2122/97 STSTTELQTYNRNFIGGDIIGGANDRLQVIFRPRVAVDPYAIGVPGVYLC
Rv1432|M.tuberculosis_H37Rv STSTTELQTYNRNFIGGDIIGGANDRLQVIFRPRVAVDPYAIGVPGVYLC
MUL_1826|M.ulcerans_Agy99 SKSTAELQAYNRNFIGGDIIGGANDGLQVIFRPRIALDPYAIGVPGVYLC
MAV_3342|M.avium_104 SRGTADLAAYNANYIGGDILGGANDGLQVILRPRVSVSPYATGVPGVYLC
TH_2994|M.thermoresistible__bu VRSTTEMSVFNPNYVGGDILTGAKDIRQLIFGPRITLHP-----------
MAB_4734|M.abscessus_ATCC_1997 VRSTTDMTVYNPNYVGGDIVTGAKDIRQLVFGPRTTAHPYRLGIPGMYIC
MMAR_1580|M.marinum_M VRSTTEMSRYNPNYVGGDIMTGAKDIRQLTFGPRVTLSPYRTGVPGTYIC
Mflv_4235|M.gilvum_PYR-GCK SVPAARLADHNANLVGGDIGVGGNNMFSALTGPALRWNPWATPIPRTYLC
Mvan_2127|M.vanbaalenii_PYR-1 SVPAARLSAHNANLVGGDIGVGGNNMVSALTGPALRWNPWSTPIPKAYLC
MSMEG_2377|M.smegmatis_MC2_155 SVPASQMSHHNANLIGGDIGVGGNNMISALTGPTPRVNPWTTPIPKAYLC
:: : .* * :**** *.:: . * *
Mb1467|M.bovis_AF2122/97 SQSAPPGAGIHGLCGYHAAESALRWLRKRR-------
Rv1432|M.tuberculosis_H37Rv SQSAPPGAGIHGLCGYHAAESALRWLRKRR-------
MUL_1826|M.ulcerans_Agy99 SQSAPPGAGIHGLCGYHAAESALQGLRKRR-------
MAV_3342|M.avium_104 SQSTPPGPGIHGLCGYHAAEAALGWLRRRGG------
TH_2994|M.thermoresistible__bu -------------------------------------
MAB_4734|M.abscessus_ATCC_1997 SAATPPGPGAHGMCGAHAAAEALRHLRASI-------
MMAR_1580|M.marinum_M SAATPPGPGAHGMCGANAAKLALAELK----------
Mflv_4235|M.gilvum_PYR-GCK SSATPPGGGVHGMAGYYAARTVLRREFGIREMPPLAP
Mvan_2127|M.vanbaalenii_PYR-1 SSATPPGGGVHGMAGFYAARTVLRREFGIRELPPLAP
MSMEG_2377|M.smegmatis_MC2_155 SSATPPGSGVHGMSGFYAARTVLRREFGLG-LPALR-