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VSTAVIVGGGPNGLTAAILLAQQGVHVTVLEAADSVGGGVRSGAATGPGLIHDYCSAIHPMAVGSPVLAG LDLEKHGLQWLWPEVDCAHPLDDGSCGVLYRDVAATANGLGRDGRRWRALFERPARNFDLLTADIMGPLL RIPRHPLALTRFGVPTVLPAAATAQLFRTRQARALFGGIAAHAFRPLHYPMTSAIGLGIITAGHRHGWPV AAGGSQSITDALSSLLAQFGGRIETGVHVTSFTQLPTADVTLFDLSPTQVADILRDHLPTSVARGLSRFR YGPGAFKVDFAIEDGVPWTNPDAGRAGTVHLGGTFAEVASTERAVHAGRMPERPFVLVGQQYLADPGRSN GNIHPLWTYAHVPHGFTGDATQALIDQIERFAPGFRDRIVATAVRSTTDMTVYNPNYVGGDIVTGAKDIR QLVFGPRTTAHPYRLGIPGMYICSAATPPGPGAHGMCGAHAAAEALRHLRASI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4734 | - | - | 100% (473) | dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3775c | - | 3e-05 | 70.97% (31) | putative monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1467 | - | 1e-170 | 60.21% (470) | dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4235 | - | 1e-87 | 39.44% (464) | hypothetical protein Mflv_4235 |
| M. tuberculosis H37Rv | Rv1432 | - | 1e-170 | 60.21% (470) | dehydrogenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_1580 | - | 0.0 | 73.08% (468) | dehydrogenase |
| M. avium 104 | MAV_3342 | - | 1e-157 | 55.58% (466) | dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_2377 | - | 4e-91 | 39.48% (466) | P49 protein |
| M. thermoresistible (build 8) | TH_4571 | - | 0.0 | 67.80% (469) | PUTATIVE dehydrogenase |
| M. ulcerans Agy99 | MUL_1826 | - | 1e-165 | 57.66% (470) | dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_2127 | - | 3e-92 | 41.38% (464) | hypothetical protein Mvan_2127 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1467|M.bovis_AF2122/97 ------------------------MTTAVVVGAGPNGLAAAIHLARHGVD
Rv1432|M.tuberculosis_H37Rv ------------------------MTTAVVVGAGPNGLAAAIHLARHGVD
MUL_1826|M.ulcerans_Agy99 ------------------------MTKAVVVGAGPNGLAAAIQLARHGVE
MAV_3342|M.avium_104 ----------------------------MVVGAGPNGLAAAIQLARRGVE
MAB_4734|M.abscessus_ATCC_1997 ------------------------MSTAVIVGGGPNGLTAAILLAQQGVH
MMAR_1580|M.marinum_M --------------------MKGASQTAIVVGGGPNGLAAAITLAKAGLQ
TH_4571|M.thermoresistible__bu VAAERSGADHGHLVPVPRRAGGGGVTTATVVGSGPNGLAAAVTLAKAGVA
Mflv_4235|M.gilvum_PYR-GCK -------------------MGSNGQVELTVVGSGPNGLAAAVICARAGVS
Mvan_2127|M.vanbaalenii_PYR-1 -------------------MGSNVQVELTVVGSGPNGLAAAVICARAGLS
MSMEG_2377|M.smegmatis_MC2_155 -------------------------MDVTVVGSGPNGLTAAVICARAGLA
:**.*****:**: *: *:
Mb1467|M.bovis_AF2122/97 VQVLEARDTIGGGARSG-ELTVPGVIHDHCSAFHPLGVGSPFWAAIDLQR
Rv1432|M.tuberculosis_H37Rv VQVLEARDTIGGGARSG-ELTVPGVIHDHCSAFHPLGVGSPFWAAIDLQR
MUL_1826|M.ulcerans_Agy99 VQVLEAHDTIGGGARSG-ELTVPGVIHDHCSAFHPLGVGSPFWNEIDLQS
MAV_3342|M.avium_104 VQVLEAGETPGGGARSS-ELTVPGVIHDLCSATHPFGVGSPFWKEIDLPS
MAB_4734|M.abscessus_ATCC_1997 VTVLEAADSVGGGVRSG-AATGPGLIHDYCSAIHPMAVGSPVLAGLDLEK
MMAR_1580|M.marinum_M VTVLEAAEEVGGGARSS-EAIVLGLVHDHCSAIHPMAVGSEFLTGLDLDR
TH_4571|M.thermoresistible__bu VTVLEAADEIGGGTRSF-EAIVPGLLHDHCSAIHPMAVGSPFINEFGLDR
Mflv_4235|M.gilvum_PYR-GCK VRVVEAQPTAGGGARTLPDPEFSGVSHDICSAVHPLALASPFFAAFDLRA
Mvan_2127|M.vanbaalenii_PYR-1 VRVVEAQPTPGGGARTLPDPEFSGVSHDICSAVHPLALASPFFAEFDLQA
MSMEG_2377|M.smegmatis_MC2_155 VRVIEAQTTPGGGARTLPDPEFGGVSHDICSAVHPLALASPFFSAYDLTA
* *:** ***.*: *: ** *** **:.:.* . .*
Mb1467|M.bovis_AF2122/97 YGLTWKWPDVDCAHPLDDGTAGVLYRSIEATAAGLGPDGKRWQRAVGDLA
Rv1432|M.tuberculosis_H37Rv YGLTWKWPDVDCAHPLDDGTAGVLYRSIEATAAGLGPDGKRWQRAVGDLA
MUL_1826|M.ulcerans_Agy99 YGLTWNWPEVDCAHPLDDGTAGVLHQSIERTAAGMGPDGKRWRCAVGDLA
MAV_3342|M.avium_104 YGLVWKWPQIDCAHPLDDGSAGVLYRSIEQTTAGMGPDATRWRRAVGDLA
MAB_4734|M.abscessus_ATCC_1997 HGLQWLWPEVDCAHPLDDGSCGVLYRDVAATANGLGRDGRRWRALFERPA
MMAR_1580|M.marinum_M HGLSWLLPDIDCVHPLDDGSAGVLHRSVGQTADGLGADGRRWRALFDWTS
TH_4571|M.thermoresistible__bu HGLRWRWPDIDCVHPLDDGTAGVLRRSVDHTAAGLGPDGRVWRALFGRPV
Mflv_4235|M.gilvum_PYR-GCK RGVTLEVPEVSYGNPLPGRRAAIGYLDIDRTCAELE-DGEPWRRLLGPLA
Mvan_2127|M.vanbaalenii_PYR-1 RGVTLAVPEVSYGNPLPGRPAAVGYRDIERTCAELD-DGASWRRLLGPLA
MSMEG_2377|M.smegmatis_MC2_155 HGVRLAVPEIAYANPLVERPAAIGYRDIDRTCAELD-DGRSWRRLLGPLA
*: *:: :** ..: .: * : *. *: .
Mb1467|M.bovis_AF2122/97 AGFDELAEDLLRPVLNMPRHPIRLARFGPRAALPATAMARRFHTERARAL
Rv1432|M.tuberculosis_H37Rv AGFDELAEDLLRPVLNMPRHPIRLARFGPRAALPATAMARRFHTERARAL
MUL_1826|M.ulcerans_Agy99 AGFDELAGDLLRPVLGVPRHPLRPAAFGPRAALPATMMARWFRTEQARAL
MAV_3342|M.avium_104 AGFDQLASDLMRPVLRVPHHPVRLARFGPRALLPATVLARWFHTEQARAL
MAB_4734|M.abscessus_ATCC_1997 RNFDLLTADIMGPLLRIPRHPLALTRFGVPTVLPAAATAQLFRTRQARAL
MMAR_1580|M.marinum_M QRFDMLAEDIMGPLLSIPGHPITLARFGVPTVLPASVLARLFRTDQGRAL
TH_4571|M.thermoresistible__bu DRFDAVNDAVMGPLLRVPKHPLTLARFGAPTVLPASALARVFRTPAARAL
Mflv_4235|M.gilvum_PYR-GCK ADCDGVVGLLLGDKRSIPPSIPAALRVAPRLLAQGTPAWGTLLGEDARAL
Mvan_2127|M.vanbaalenii_PYR-1 DDCDGVVGLLLGDKRSIPPSIPAAVRVAPRLLAQGSPAWGTLAGEDARAL
MSMEG_2377|M.smegmatis_MC2_155 DDCDGVVGLMLGDKRSLPPSIPAALRVAPRMLGQGTALWRLLRGDDARAL
* : :: :* .. .: : .***
Mb1467|M.bovis_AF2122/97 FGGAAAHVYTRLDRPLTASLGLMILASGHRHGWPVARGGSGSITKALAAA
Rv1432|M.tuberculosis_H37Rv FGGAAAHVYTRLDRPLTASLGLMILASGHRHGWPVARGGSGSITKALAAA
MUL_1826|M.ulcerans_Agy99 FGGAAAHVYTRLDRPLTASLGLMILASGHRYGWPVAQGGSGSITAALGAA
MAV_3342|M.avium_104 FGGAAAHIYTRLDRPLTASLGLLFLASGHRYGWPVAEGGSGSIIHALVAA
MAB_4734|M.abscessus_ATCC_1997 FGGIAAHAFRPLHYPMTSAIGLGIITAGHRHGWPVAAGGSQSITDALSSL
MMAR_1580|M.marinum_M FGGVAAHAFRPLHYPMTSAIGLGIITAGHRHGWPVAAGGSQSITNALVAT
TH_4571|M.thermoresistible__bu WGGVAAHAFRPLHLPMTSAIGVGIITAGHRHGWAVAEGGSRAITDAMAAR
Mflv_4235|M.gilvum_PYR-GCK FTGVAAHTISRMPSLVASGAGLMLSTLAHAVGWPIPVGGSQAIPDALIAD
Mvan_2127|M.vanbaalenii_PYR-1 FTGVAAHTISRMPSLVSAGAGLMLATLGHTVGWPVPSGGSQAIPDALLAD
MSMEG_2377|M.smegmatis_MC2_155 FSGVAAHTISPMPSLVSAGAGLMLATLAHAVGWPIPIGGSQAIPDALIAD
: * *** : :::. *: : : .* **.:. *** :* *: :
Mb1467|M.bovis_AF2122/97 LDAYGGTVATGVTVTSRRDIPDADIVMLDLSPAAVLGIYGDVMPTRINRS
Rv1432|M.tuberculosis_H37Rv LDAYGGTVATGVTVTSRRDIPDADIVMLDLSPAAVLGIYGDVMPTRINRS
MUL_1826|M.ulcerans_Agy99 LDALGGVVATGITVTSRRDIPDADIVMLDLSPANVLTLYGDEMPARIKRS
MAV_3342|M.avium_104 LRAHGGDVATGVTVSDRRDIPDADIVMLDLTPAAALRLYGELMPARIARS
MAB_4734|M.abscessus_ATCC_1997 LAQFGGRIETGVHVTSFTQLPTADVTLFDLSPTQVADILRDHLPTSVARG
MMAR_1580|M.marinum_M LDELGGKIETGVRVQTASQLPPADVTMFDLAPDAVAGILGDRMPGRIARA
TH_4571|M.thermoresistible__bu LRELGGTIETGVRVRDIADLPPTTITVFDLAPEAVAEILGDRLPPRVARA
Mflv_4235|M.gilvum_PYR-GCK LRAHGGELVVGEEVST----PPSGVVLYDTAPTALLDIYGDRLPSRYART
Mvan_2127|M.vanbaalenii_PYR-1 LQAHGGELVLGEEVTS----PPSGVVLYDTAPTALLRIYGDRLPPGYAKT
MSMEG_2377|M.smegmatis_MC2_155 LRAHGGELVLGEEVTE----PPSGVVVYDTAPTALLSIYRDAVPPRYAKA
* ** : * * * : :.: * :* : : :* :
Mb1467|M.bovis_AF2122/97 YRRYRAGSSAFKVDFAIEGDVGWTNPDCRRAGTVHLGGTFAEIADTERQR
Rv1432|M.tuberculosis_H37Rv YRRYRAGSSAFKVDFAIEGDVGWTNPDCRRAGTVHLGGTFAEIADTERQR
MUL_1826|M.ulcerans_Agy99 YRRYREGSSAFKVDFAIEGDIPWTNPDCRRAGTVHLGGTFAEIADTERQR
MAV_3342|M.avium_104 YRRYRQGSSAFKVDFAVEGDIPWTNPHCARAGSVHLGGSFAEIADTERQR
MAB_4734|M.abscessus_ATCC_1997 LSRFRYGPGAFKVDFAIEDGVPWTNPDAGRAGTVHLGGTFAEVASTERAV
MMAR_1580|M.marinum_M YNKFRRGPGAFKVDFAIEGAVPWTNPQARRAGTVHLGGPYAELAAAEREV
TH_4571|M.thermoresistible__bu YRAFRRGPGAFKVDFAVEGGVPWCNPDAHRAGTVHVGGTFEEIAATERDV
Mflv_4235|M.gilvum_PYR-GCK LRRYRYGPGVAKVDFVLSGEIPWRDKRLASAPTLHMGGDRATMALAEKDI
Mvan_2127|M.vanbaalenii_PYR-1 LRRYRYGPGVAKVDFVLSGEIPWRDPRLANAPTLHLGGDRATMARAEKDV
MSMEG_2377|M.smegmatis_MC2_155 LRNYTYGSGVAKVDFVLSGEIPWRDPRLAQSPTLHLGGSREQMALAESEV
: *... ****.:.. : * : : ::*:** :* :*
Mb1467|M.bovis_AF2122/97 AQGTMVQRPFVLVGQQYLADPSRS-VGNINPIWAYAHVPFGYTGDATAAV
Rv1432|M.tuberculosis_H37Rv AQGTMVQRPFVLVGQQYLADPSRS-VGNINPIWAYAHVPFGYTGDATAAV
MUL_1826|M.ulcerans_Agy99 AQGRMVQRPFVLIGQQYLADPSRS-AGNINPIWAYAHVPFGYAGDATAAV
MAV_3342|M.avium_104 AQGKLAPRPFVLVGQQYLADPSRS-AGGINPIWAYAHVPFGYTGDATALV
MAB_4734|M.abscessus_ATCC_1997 HAGRMPERPFVLVGQQYLADPGRS-NGNIHPLWTYAHVPHGFTGDATQAL
MMAR_1580|M.marinum_M HAGRMPQRPFVLVGQQYLADPERS-VGNIHPLWTYAHVPNGYTGDATAAI
TH_4571|M.thermoresistible__bu NAGRMPERPFVLVAQQYVADPGRS-VGDIHPVWSYAHVPHGYPGDATEAV
Mflv_4235|M.gilvum_PYR-GCK AEGRHAQWPMVLASLPHLADPGRIDAAGRRPLWTYAHVPAGSTVDMAETI
Mvan_2127|M.vanbaalenii_PYR-1 AAGRHAEWPMVLASLPHLADPGRVDPQGRRPLWTYAHVPAGSTVDMAEAV
MSMEG_2377|M.smegmatis_MC2_155 ARGRHAEWPMVLAASPHIADPGRIDARGRRPLWTYAHVPSGSPVDMADTV
* *:** . ::*** * . .*:*:***** * . * : :
Mb1467|M.bovis_AF2122/97 IDQIERFAPGFRDRIVATVSTSTTELQTYNRNFIGGDIIGGANDRLQVIF
Rv1432|M.tuberculosis_H37Rv IDQIERFAPGFRDRIVATVSTSTTELQTYNRNFIGGDIIGGANDRLQVIF
MUL_1826|M.ulcerans_Agy99 IDQIERFAPGFRDRITATVSKSTAELQAYNRNFIGGDIIGGANDGLQVIF
MAV_3342|M.avium_104 VDQIERFAPGFRDRVVATVSRGTADLAAYNANYIGGDILGGANDGLQVIL
MAB_4734|M.abscessus_ATCC_1997 IDQIERFAPGFRDRIVATAVRSTTDMTVYNPNYVGGDIVTGAKDIRQLVF
MMAR_1580|M.marinum_M IAQIERFAPGFREHIVGQTVRSTTEMSRYNPNYVGGDIMTGAKDIRQLTF
TH_4571|M.thermoresistible__bu VAQIERFAPGFRDRIVGYRTESAEGMARFNANFTGGDILTGAKDIRQLTF
Mflv_4235|M.gilvum_PYR-GCK TGVFERFAPGFRDLVVGVRSVPAARLADHNANLVGGDIGVGGNNMFSALT
Mvan_2127|M.vanbaalenii_PYR-1 TEVIERFAPGFRDVVVGVRSVPAARLSAHNANLVGGDIGVGGNNMVSALT
MSMEG_2377|M.smegmatis_MC2_155 TSILERFAPGFRDLVVAVRSVPASQMSHHNANLIGGDIGVGGNNMISALT
:********: :.. : : .* * **** *.:: .
Mb1467|M.bovis_AF2122/97 RPRVAVDPYAIGVPGVYLCSQSAPPGAGIHGLCGYHAAESALRWLRKRR-
Rv1432|M.tuberculosis_H37Rv RPRVAVDPYAIGVPGVYLCSQSAPPGAGIHGLCGYHAAESALRWLRKRR-
MUL_1826|M.ulcerans_Agy99 RPRIALDPYAIGVPGVYLCSQSAPPGAGIHGLCGYHAAESALQGLRKRR-
MAV_3342|M.avium_104 RPRVSVSPYATGVPGVYLCSQSTPPGPGIHGLCGYHAAEAALGWLRRRGG
MAB_4734|M.abscessus_ATCC_1997 GPRTTAHPYRLGIPGMYICSAATPPGPGAHGMCGAHAAAEALRHLRASI-
MMAR_1580|M.marinum_M GPRVTLSPYRTGVPGTYICSAATPPGPGAHGMCGANAAKLALAELK----
TH_4571|M.thermoresistible__bu GPRITLSPYATGAPGYYICSAATPPGPGAHGMCGYHAAQTALRELAR---
Mflv_4235|M.gilvum_PYR-GCK GPALRWNPWATPIPRTYLCSSATPPGGGVHGMAGYYAARTVLRREFGIRE
Mvan_2127|M.vanbaalenii_PYR-1 GPALRWNPWSTPIPKAYLCSSATPPGGGVHGMAGFYAARTVLRREFGIRE
MSMEG_2377|M.smegmatis_MC2_155 GPTPRVNPWTTPIPKAYLCSSATPPGSGVHGMSGFYAARTVLRREFGLG-
* *: * *:** ::*** * **:.* ** .*
Mb1467|M.bovis_AF2122/97 ------
Rv1432|M.tuberculosis_H37Rv ------
MUL_1826|M.ulcerans_Agy99 ------
MAV_3342|M.avium_104 ------
MAB_4734|M.abscessus_ATCC_1997 ------
MMAR_1580|M.marinum_M ------
TH_4571|M.thermoresistible__bu ------
Mflv_4235|M.gilvum_PYR-GCK MPPLAP
Mvan_2127|M.vanbaalenii_PYR-1 LPPLAP
MSMEG_2377|M.smegmatis_MC2_155 LPALR-