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M. thermoresistible (build 8) TH_2871 (-)

annotation: beta-lactamase domain protein
coordinates: 656636 - 657550
length: 305

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2871--100% (305)beta-lactamase domain protein
M. thermoresistible (build 8)TH_0195-6e-1728.42% (278) metal dependent hydrolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCK-----
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4947-5e-3632.04% (309) Beta-lactamase-like protein
M. marinum M-----
M. avium 104MAV_4762-8e-0524.22% (161) metallo-beta-lactamase superfamily protein
M. smegmatis MC2 155MSMEG_0610-6e-9255.74% (296) beta-lactamase
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_5633-4e-5740.40% (302) beta-lactamase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_2871|M.thermoresistible__bu      ----MIKTIEIGAVTVTRVMEWEGLFAPG-TELIPDSDDRFWESERALLA
MSMEG_0610|M.smegmatis_MC2_155      -----MNEIVLGDVTVTRVMEYYGSVRLSPQTFFPESEPAAWQRNEHWLV
Mvan_5633|M.vanbaalenii_PYR-1       ----MTGQVRLGRATLSRVVEVRAQMRTS---LFAQTPAAAWPANADLLE
MAB_4947|M.abscessus_ATCC_1997      MFSAAVRTFTVGDATVTQLTELDVWPIKP-HHWYPALSEEQLVFARANYA
MAV_4762|M.avium_104                ------------MAELVQVTDAVHLARGD---------------------
                                                 . : :: :                             

TH_2871|M.thermoresistible__bu      PDHWEPADRMVRACLQTFVLQSEGRTILVDTGAGNHKERPYLPVFGHLET
MSMEG_0610|M.smegmatis_MC2_155      PDFVDPDADVCVSAIQSWVLRSGGATIVVDTGVGNNKERPDTPVWHRLQT
Mvan_5633|M.vanbaalenii_PYR-1       PLFWDRGADEWKIAIQTWVIRVDGLTVLVDTGVGNHRNRPHMPPLHQLDT
MAB_4947|M.abscessus_ATCC_1997      PSAVSDDGSELIFAIHNYVIELADTIIVVDTCSGNHKNRPLFADLHMLNT
MAV_4762|M.avium_104                -------------AVNWTLVADDTGVMLVDAGYPGDRE------------
                                                 .::  ::      ::**:   ..::            

TH_2871|M.thermoresistible__bu      DFLDRLAAAGFRPEDIDLVINTHVHVDHVGWNTYLHDR--------EWVP
MSMEG_0610|M.smegmatis_MC2_155      DYLDNLAAAGVQPADVDYVINTHVHVDHVGWNTYLDNG--------HWAP
Mvan_5633|M.vanbaalenii_PYR-1       PYLKALTDAGVSPEDVDVVVNTHLHTDHVGWNTRLSAASGAGTGGGAWTP
MAB_4947|M.abscessus_ATCC_1997      DYLTRLEQSGYSPEAVDIVVNTHLHLDHCGWNTRLVEG--------TWRP
MAV_4762|M.avium_104                DVLGSLAELGYGPGDVRAIVLTHAHIDHLGTAIWLASEHG--------IP
                                      *  *   *  *  :  :: ** * ** *    *              *

TH_2871|M.thermoresistible__bu      TFPNARYVFSRRDFDFWNPLNGHERRGALVNQN--MFEDSVLPVQQAGLA
MSMEG_0610|M.smegmatis_MC2_155      TFPNATYLIPRADFEFWNPEN--RPSSSVDHRN--LFMDSVAPIHAAGQA
Mvan_5633|M.vanbaalenii_PYR-1       TFPNARYLMPELDYRHFSPDN---PDVADGMRI--VFADSVSPVEP--QM
MAB_4947|M.abscessus_ATCC_1997      TFPAATYLFHHTELKYIRAQWESAPIDQWQDNGGWVYEDSILPVLEHAPY
MAV_4762|M.avium_104                VYCHADEVG-HAKREYLEQVSIVDVALRIWRPRWAKWTAHVVRSGGLIRD
                                    .:  *  :  . .  .                    :   :         

TH_2871|M.thermoresistible__bu      DMWEGDTHRID---ANLTLELAPGHTPGLSVLKLESEGERAVFVGDLLHS
MSMEG_0610|M.smegmatis_MC2_155      LLWE-DSFDIN---ADLRLQAAPGHTPGSSIVTLESGSDRAVFVGDMLHT
Mvan_5633|M.vanbaalenii_PYR-1       ELFS-GDHRVS---DSLWLRPAPGHTPGSTMVWLDAG-VPAVFVGDLTHS
MAB_4947|M.abscessus_ATCC_1997      GFVKSGQVLHSYGSTHIRALDAGGHTPGHVAIEVRAADTGLLIAGDALHH
MAV_4762|M.avium_104                GIPTAQPLTAEVA-AGLPGRPTPVFSPGHTNGHCSYLIDGVLVSGDALIT
                                     :        .     :    :  .:**             :. **    

TH_2871|M.thermoresistible__bu      PVQILRPDWNSCFCEDPGRARASRRRVLSWAADNNALLVPAHLGGDHAAE
MSMEG_0610|M.smegmatis_MC2_155      PLQFVEPDVNSCFCEDPAQARATRRRVLGWAADTRTLVVPAHLGGHGAAE
Mvan_5633|M.vanbaalenii_PYR-1       PIQIPRPDDPCAFDVDPMAAARSRHRILTEASRRRAAVIPAHYPGRGGAT
MAB_4947|M.abscessus_ATCC_1997      PMQAQFPDLPFYADADPAQAVATRRALLGRCADENLKLLTAHFPAHSPLG
MAV_4762|M.avium_104                GHPLLRHRGP---QLLPAIFSYSQRDCIRTLSALALLDTEVLLPGHG--D
                                                    *     :::  :   :        .   .     

TH_2871|M.thermoresistible__bu      VVRAGDDFAVKGWAAFRSAGAV-
MSMEG_0610|M.smegmatis_MC2_155      LARDGDTFAIKEWAPFERVTTHV
Mvan_5633|M.vanbaalenii_PYR-1       VVARGNTFLVDQWLGFPEI----
MAB_4947|M.abscessus_ATCC_1997      VRRSGAAFTWDGSRAID------
MAV_4762|M.avium_104                VWRGPIKEATDAALALATGR---
                                    :         .    :