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M. avium 104 MAV_4762 (-)

annotation: metallo-beta-lactamase superfamily protein
coordinates: 4888459 - 4889202
length: 247

MAELVQVTDAVHLARGDAVNWTLVADDTGVMLVDAGYPGDREDVLGSLAELGYGPGDVRAIVLTHAHIDH
LGTAIWLASEHGIPVYCHADEVGHAKREYLEQVSIVDVALRIWRPRWAKWTAHVVRSGGLIRDGIPTAQP
LTAEVAAGLPGRPTPVFSPGHTNGHCSYLIDGVLVSGDALITGHPLLRHRGPQLLPAIFSYSQRDCIRTL
SALALLDTEVLLPGHGDVWRGPIKEATDAALALATGR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_4762--100% (247)metallo-beta-lactamase superfamily protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0414c-1e-10973.77% (244) beta lactamase like protein
M. gilvum PYR-GCKMflv_0212-2e-8759.83% (234) beta-lactamase domain-containing protein
M. tuberculosis H37RvRv0406c-1e-10973.77% (244) beta lactamase like protein
M. leprae Br4923MLBr_00270-1e-11373.66% (243) hypothetical protein MLBr_00270
M. abscessus ATCC 19977MAB_4231-5e-7954.55% (242) Beta-lactamase-like protein
M. marinum MMMAR_0708-1e-10070.25% (242) beta lactamase-like protein
M. smegmatis MC2 155MSMEG_0775-5e-9061.00% (241) metallo-beta-lactamase superfamily protein
M. thermoresistible (build 8)TH_2303-5e-9064.14% (237) BETA LACTAMASE LIKE PROTEIN
M. ulcerans Agy99MUL_2815-1e-10070.25% (242) beta lactamase-like protein
M. vanbaalenii PYR-1Mvan_0697-2e-9464.98% (237) beta-lactamase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0212|M.gilvum_PYR-GCK          -------------------MAPVVTAVTDRVHFVRTELVNWTLVRDDDGV
Mvan_0697|M.vanbaalenii_PYR-1       -------------------MALALTAITDRVHFAQTDLVNWTLVAEDGGV
MSMEG_0775|M.smegmatis_MC2_155      -------------------MAVALNKITDRVHFARTELVNWTLVTGDDGV
TH_2303|M.thermoresistible__bu      ----------------MAAPAVRLEQITDSVHFANTDLVNWVLVTDGTGV
Mb0414c|M.bovis_AF2122/97           MVATRGTRLAALALAPRLAGMAELVQITDKVHLARGHAVNWVLVTDDTGV
Rv0406c|M.tuberculosis_H37Rv        MVATRGTRLAALALAPRLAGMAELVQITDKVHLARGHAVNWVLVTDDTGV
MMAR_0708|M.marinum_M               MPHQR----------------TELVQVTDKVHLAQGPAVNWVLVTDETGV
MUL_2815|M.ulcerans_Agy99           MPHQR----------------TELVQVTDKVHLAQGPAVNWVLVTDETGV
MAV_4762|M.avium_104                --------------------MAELVQVTDAVHLARGDAVNWTLVADDTGV
MLBr_00270|M.leprae_Br4923          ------------------MAAATLFQVTDSVHFARGDAVNWALVADDTGV
MAB_4231|M.abscessus_ATCC_1997      --------------------MVEITQVSDAVHVVNGEAVNWVIASDDSGV
                                                           :  ::* **...   ***.:.    **

Mflv_0212|M.gilvum_PYR-GCK          ILIDAGFPGHRDEVLTSLHGLGFGVGDVRAILLTHAHIDHFGTAIWFAAT
Mvan_0697|M.vanbaalenii_PYR-1       LLIDAGYPGHREEVLESLGRLGFGATDVRAILLTHAHIDHFGSAMWFARE
MSMEG_0775|M.smegmatis_MC2_155      LLIDAGFPGQREDVLDSVRQLGFGPDDIKAVLLTHAHVDHFGTAIWLAKT
TH_2303|M.thermoresistible__bu      VLIDAGYPGQRGLVLHSLRQLGFGPDAVRAILLTHAHIDHLGSAIWFAKT
Mb0414c|M.bovis_AF2122/97           LLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLTHAHIDHLGSAIWFARE
Rv0406c|M.tuberculosis_H37Rv        LLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLTHAHIDHLGSAIWFARE
MMAR_0708|M.marinum_M               MLIDAGYPGDRNNVLTSLRTLGYGPGDVRAILLTHAHIDHLGTAIWFAAQ
MUL_2815|M.ulcerans_Agy99           MLIDAGYPGDRNNVLTSLRTLGYGPGDVRAILLTHAHIDHLGTAIWFAAQ
MAV_4762|M.avium_104                MLVDAGYPGDREDVLGSLAELGYGPGDVRAIVLTHAHIDHLGTAIWLASE
MLBr_00270|M.leprae_Br4923          MLIDTGYPGDRDDVVASLRQLGYEAGDVRAILLTHAHIDHMGSAIWFASK
MAB_4231|M.abscessus_ATCC_1997      TLFDSGYPGDRDDVLKSIAALGHKPQDVRAVVLTHGHIDHMGTAIWWAAE
                                     *.*:*:**.*  *: *:  **.    ::*::***.*:**:*:*:* *  

Mflv_0212|M.gilvum_PYR-GCK          HGTPVYCHADEVAHSRRDHLEQASPIDIAKHAWQPTWLKWSVSIIGKGAL
Mvan_0697|M.vanbaalenii_PYR-1       HGTPVYCHADEVGHAKREYLEQASPLAVAAHAWQPRWLKWSLTLIRKGGL
MSMEG_0775|M.smegmatis_MC2_155      YGTPVYCHADEVGHARREYLEQATPAGVARQAWQPRWLKWALAISRQGAF
TH_2303|M.thermoresistible__bu      HGTPVFCHADEVGHAKRAYLEQVSPLDLAGQLWRPRWLTWSLTAVRTGAL
Mb0414c|M.bovis_AF2122/97           HSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHLLRRGGL
Rv0406c|M.tuberculosis_H37Rv        HSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHLLRRGGL
MMAR_0708|M.marinum_M               HGTPVYCDANEVGHAKREYHESASPLDVVLRSWRPRTALWGIHLVFRGGL
MUL_2815|M.ulcerans_Agy99           HGTPVYCDANEVGHAKREYHESASPLDVVLRSWRPRTALWGIHLVFRGGL
MAV_4762|M.avium_104                HGIPVYCHADEVGHAKREYLEQVSIVDVALRIWRPRWAKWTAHVVRSGGL
MLBr_00270|M.leprae_Br4923          HRTPVYCHADEVGHTKREYLEQVSLLNIAMRVWQPRWAIWSGHVLRSGGL
MAB_4231|M.abscessus_ATCC_1997      HGVPVYAHNAELGNVRRDYVDQAEPLKVVLNLWRPGWLPWVIHAMRLGAG
                                    :  **:..  *:.: :* : :..    :. . *:*    *       *. 

Mflv_0212|M.gilvum_PYR-GCK          TRAGIASTAPLTDHIAAALPGSPVCIPTPGHTGGHCSYVVDG-VLVSGDA
Mvan_0697|M.vanbaalenii_PYR-1       DRTGIPTTAALSEDIAAGLPGAPVCVPTPGHTGGHCSYVVDG-VLVSGDA
MSMEG_0775|M.smegmatis_MC2_155      DHSGIPSTQAFTPEIG--LPGNPTAIPTPGHTGGHCSYLVDG-VLVAGDA
TH_2303|M.thermoresistible__bu      VREGIPGTRALTEDVAAQLPGQPVVIPSPGHTAGHCSYLIGE-VLVSGDA
Mb0414c|M.bovis_AF2122/97           TGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDG-VLASGDA
Rv0406c|M.tuberculosis_H37Rv        TGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDG-VLASGDA
MMAR_0708|M.marinum_M               RRAGVPSTQALSAEVAAALPGHPIPIPTPGHTSGHCSYLVDG-VLASGDA
MUL_2815|M.ulcerans_Agy99           RRAGVPSTQALSAEVAAALPGHPIPIPTPGHTSGHCSYLVDG-VLASGDA
MAV_4762|M.avium_104                IRDGIPTAQPLTAEVAAGLPGRPTPVFSPGHTNGHCSYLIDG-VLVSGDA
MLBr_00270|M.leprae_Br4923          IRGGIPTAQPLTAETAAGLPGHPMAIFTPGHTGGHCSYVVDG-VLISGDA
MAB_4231|M.abscessus_ATCC_1997      VRDGIPTAAPLGPELAD-LPGAPAPIPTPGHSGGHCSFLVAGHVLVVGDA
                                       *:. : .:  . .  *** *  : :***: ****:::   **  ***

Mflv_0212|M.gilvum_PYR-GCK          LITGHPVASRRGPQLLPSVFNHDEDACRRSLTTLGALDTEVILPGHGPLW
Mvan_0697|M.vanbaalenii_PYR-1       LITGHPVSRRRGPQLLPSVFNHDEVACLRSLEALGMLDTEVMLPGHGPVW
MSMEG_0775|M.smegmatis_MC2_155      LVTGHPTSSRRGPQLLHQVFNHDQQACLRSLGALGLLDTEVLLPGHGDVW
TH_2303|M.thermoresistible__bu      LVTGHPVAPRRGPQLLPEVFNHDQDSCVRSVAALGLLDAEVLLPGHGPVW
Mb0414c|M.bovis_AF2122/97           LITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELW
Rv0406c|M.tuberculosis_H37Rv        LITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELW
MMAR_0708|M.marinum_M               LITGHPMLRHRGPQLLPAVFSKVQERCIRSLSTLAQVEADTLAPGHGSLW
MUL_2815|M.ulcerans_Agy99           LITGHPMLRHRGPQLLPAVFSKVQERCIRSLSTLAQVEADTLAPGHGSLW
MAV_4762|M.avium_104                LITGHPLLRHRGPQLLPAIFSYSQRDCIRTLSALALLDTEVLLPGHGDVW
MLBr_00270|M.leprae_Br4923          LITGHPLLRHRGPQLLTAVFSHSQKQCLRSLDALGLLETRILAPGHGELW
MAB_4231|M.abscessus_ATCC_1997      IITGHPVAKRSGPQLLPTPFTKDMEQARRSAEALADVDADVLAPGHGPAW
                                    ::****   : *****   *.     . *:  :*. :::  : ****  *

Mflv_0212|M.gilvum_PYR-GCK          RGPVRDAAAQAAQASVR------
Mvan_0697|M.vanbaalenii_PYR-1       RGPVRDAVAQATTAEP-------
MSMEG_0775|M.smegmatis_MC2_155      RGSIREMADQAASSAPSPAR---
TH_2303|M.thermoresistible__bu      RGEISTAARLATPA---------
Mb0414c|M.bovis_AF2122/97           HGPIRKATDEALERAQKSNHVFR
Rv0406c|M.tuberculosis_H37Rv        HGPIRKATDEALERAQKSNHVFR
MMAR_0708|M.marinum_M               RGPIRLATEEARARAQR------
MUL_2815|M.ulcerans_Agy99           RGPIRLATEEARARAQR------
MAV_4762|M.avium_104                RGPIKEATDAALALATGR-----
MLBr_00270|M.leprae_Br4923          HGPIREATEAALKQAGALTR---
MAB_4231|M.abscessus_ATCC_1997      IGSLRDAVQIALNT---------
                                     * :   .  *