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M. smegmatis MC2 155 MSMEG_0610 (-)

annotation: beta-lactamase
coordinates: 686934 - 687842
length: 302

MNEIVLGDVTVTRVMEYYGSVRLSPQTFFPESEPAAWQRNEHWLVPDFVDPDADVCVSAIQSWVLRSGGA
TIVVDTGVGNNKERPDTPVWHRLQTDYLDNLAAAGVQPADVDYVINTHVHVDHVGWNTYLDNGHWAPTFP
NATYLIPRADFEFWNPENRPSSSVDHRNLFMDSVAPIHAAGQALLWEDSFDINADLRLQAAPGHTPGSSI
VTLESGSDRAVFVGDMLHTPLQFVEPDVNSCFCEDPAQARATRRRVLGWAADTRTLVVPAHLGGHGAAEL
ARDGDTFAIKEWAPFERVTTHV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0610--100% (302)beta-lactamase
M. smegmatis MC2 155MSMEG_3376-2e-7046.49% (299) beta-lactamase
M. smegmatis MC2 155MSMEG_3427-3e-2128.33% (293) metal dependent hydrolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCK-----
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4947-1e-3835.02% (297) Beta-lactamase-like protein
M. marinum M-----
M. avium 104-----
M. thermoresistible (build 8)TH_2871-4e-9255.74% (296) PUTATIVE beta-lactamase domain protein
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_5633-2e-6443.09% (304) beta-lactamase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_0610|M.smegmatis_MC2_155      -----MNEIVLGDVTVTRVMEYYGSVRLSPQTFFPESEPAAWQRNEHWLV
TH_2871|M.thermoresistible__bu      ----MIKTIEIGAVTVTRVMEWEGLFAPG-TELIPDSDDRFWESERALLA
Mvan_5633|M.vanbaalenii_PYR-1       ----MTGQVRLGRATLSRVVEVRAQMRTS---LFAQTPAAAWPANADLLE
MAB_4947|M.abscessus_ATCC_1997      MFSAAVRTFTVGDATVTQLTELDVWPIKP-HHWYPALSEEQLVFARANYA
                                            . :* .*:::: *             .               

MSMEG_0610|M.smegmatis_MC2_155      PDFVDPDADVCVSAIQSWVLRSGGATIVVDTGVGNNKERPDTPVWHRLQT
TH_2871|M.thermoresistible__bu      PDHWEPADRMVRACLQTFVLQSEGRTILVDTGAGNHKERPYLPVFGHLET
Mvan_5633|M.vanbaalenii_PYR-1       PLFWDRGADEWKIAIQTWVIRVDGLTVLVDTGVGNHRNRPHMPPLHQLDT
MAB_4947|M.abscessus_ATCC_1997      PSAVSDDGSELIFAIHNYVIELADTIIVVDTCSGNHKNRPLFADLHMLNT
                                    *   .        .::.:*:.  .  ::***  **:::**  .    *:*

MSMEG_0610|M.smegmatis_MC2_155      DYLDNLAAAGVQPADVDYVINTHVHVDHVGWNTYLDNG--------HWAP
TH_2871|M.thermoresistible__bu      DFLDRLAAAGFRPEDIDLVINTHVHVDHVGWNTYLHDR--------EWVP
Mvan_5633|M.vanbaalenii_PYR-1       PYLKALTDAGVSPEDVDVVVNTHLHTDHVGWNTRLSAASGAGTGGGAWTP
MAB_4947|M.abscessus_ATCC_1997      DYLTRLEQSGYSPEAVDIVVNTHLHLDHCGWNTRLVEG--------TWRP
                                     :*  *  :*  *  :* *:***:* ** **** *            * *

MSMEG_0610|M.smegmatis_MC2_155      TFPNATYLIPRADFEFWNPEN--RPSSSVDHRN--LFMDSVAPIHAAGQA
TH_2871|M.thermoresistible__bu      TFPNARYVFSRRDFDFWNPLNGHERRGALVNQN--MFEDSVLPVQQAGLA
Mvan_5633|M.vanbaalenii_PYR-1       TFPNARYLMPELDYRHFSPDN---PDVADGMRI--VFADSVSPVEP--QM
MAB_4947|M.abscessus_ATCC_1997      TFPAATYLFHHTELKYIRAQWESAPIDQWQDNGGWVYEDSILPVLEHAPY
                                    *** * *:: . :  .  .            .   :: **: *:      

MSMEG_0610|M.smegmatis_MC2_155      LLWE-DSFDIN---ADLRLQAAPGHTPGSSIVTLESGSDRAVFVGDMLHT
TH_2871|M.thermoresistible__bu      DMWEGDTHRID---ANLTLELAPGHTPGLSVLKLESEGERAVFVGDLLHS
Mvan_5633|M.vanbaalenii_PYR-1       ELFS-GDHRVS---DSLWLRPAPGHTPGSTMVWLDAG-VPAVFVGDLTHS
MAB_4947|M.abscessus_ATCC_1997      GFVKSGQVLHSYGSTHIRALDAGGHTPGHVAIEVRAADTGLLIAGDALHH
                                     : . .    .     :    * *****   : : :     ::.**  * 

MSMEG_0610|M.smegmatis_MC2_155      PLQFVEPDVNSCFCEDPAQARATRRRVLGWAADTRTLVVPAHLGGHGAAE
TH_2871|M.thermoresistible__bu      PVQILRPDWNSCFCEDPGRARASRRRVLSWAADNNALLVPAHLGGDHAAE
Mvan_5633|M.vanbaalenii_PYR-1       PIQIPRPDDPCAFDVDPMAAARSRHRILTEASRRRAAVIPAHYPGRGGAT
MAB_4947|M.abscessus_ATCC_1997      PMQAQFPDLPFYADADPAQAVATRRALLGRCADENLKLLTAHFPAHSPLG
                                    *:*   **       **  *  :*: :*  .:  .  ::.**  .     

MSMEG_0610|M.smegmatis_MC2_155      LARDGDTFAIKEWAPFERVTTHV
TH_2871|M.thermoresistible__bu      VVRAGDDFAVKGWAAFRSAGAV-
Mvan_5633|M.vanbaalenii_PYR-1       VVARGNTFLVDQWLGFPEI----
MAB_4947|M.abscessus_ATCC_1997      VRRSGAAFTWDGSRAID------
                                    :   *  *  .    :