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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2727 | - | - | 100% (111) | thiopurine S-methyltransferase (tpmt) superfamily protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3243 | - | 1e-24 | 53.61% (97) | methyltransferase type 12 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2640 | - | 2e-29 | 58.49% (106) | methyltransferase |
| M. avium 104 | MAV_2957 | - | 4e-30 | 61.11% (108) | thiopurine S-methyltransferase (tpmt) superfamily protein |
| M. smegmatis MC2 155 | MSMEG_4544 | - | 3e-28 | 68.29% (82) | methyltransferase small subunit |
| M. ulcerans Agy99 | MUL_3115 | - | 2e-30 | 59.43% (106) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_2956 | - | 2e-25 | 61.18% (85) | methyltransferase type 12 |
CLUSTAL 2.0.9 multiple sequence alignment
TH_2727|M.thermoresistible__bu --------------------------------------------------
MAV_2957|M.avium_104 ------------------------------------MGE-------ADRH
MMAR_2640|M.marinum_M MSRTAERADRLSIRYPVCSPTAQVRRSCRGRRMVARVAE-------SDRR
MUL_3115|M.ulcerans_Agy99 ---------------------------------MARVAE-------SDRR
MSMEG_4544|M.smegmatis_MC2_155 ------------------------------------MSE-------HDRA
Mflv_3243|M.gilvum_PYR-GCK ------------------------------------MAD-------ADRE
Mvan_2956|M.vanbaalenii_PYR-1 ------------------------------------MPATSYSRLMTDRG
TH_2727|M.thermoresistible__bu --------------------------------------------------
MAV_2957|M.avium_104 RWDERYAANGPPP---LSSVAPPGVFARHADVFPAAGRALDLACGQGTAA
MMAR_2640|M.marinum_M RWDRRYASLGPAA---VSAARPPALLQAHLKLVPTAGRALDLGCGQGLGA
MUL_3115|M.ulcerans_Agy99 RWDRRYASLGPAA---VSAVRPPALLQAHLKLVPAAGRALDLGCGQGLGA
MSMEG_4544|M.smegmatis_MC2_155 RWDAAYTDRPLGAGLPDGPAGPPRAFAGHVDEFPTAGSALDVACGSGENS
Mflv_3243|M.gilvum_PYR-GCK HWDRRYTARDRTL---AGHAALPAVFASHSDLFPTAGYAIELACGTGAAA
Mvan_2956|M.vanbaalenii_PYR-1 HWDRRYTARGSLS---VDDVALPARFTPFADVFPTGGRAVELACGAGAAS
TH_2727|M.thermoresistible__bu -------MDVLGVDVSPIAIAQARALAAANGVSNRCRFEVFDLDDGLPAG
MAV_2957|M.avium_104 VWLALRGLRVLGLDVSPVAIGQARDLARRAGVGERCRFDVADLDRGLPVG
MMAR_2640|M.marinum_M VWLARRGLDVLGLDISPVAIAQARDLAERSGVSARCCFDVVDLDDGLPDG
MUL_3115|M.ulcerans_Agy99 VWLARRGLDVLGLDISPVAIAQARDLAERSGVSARCRFDVVDLDDGLPDG
MSMEG_4544|M.smegmatis_MC2_155 VWLARRGLHVWGIDVSPVAITQATQFAARNGVAQRCRFDVVDLDDGLPDG
Mflv_3243|M.gilvum_PYR-GCK VWLARRGLRVWACDISPVAVAAATERARLDGQSERCTFEVVDLDHGIPGV
Mvan_2956|M.vanbaalenii_PYR-1 VWLAKRGLSVWACDASSVAIAQAEDLAERCGQAHRCRFEVVDLDAGLPAG
: * . * *.:*: * * * . ** *:* *** *:*
TH_2727|M.thermoresistible__bu PPADVILCHLYRDPRLDRPIIERLAPGGLLAITVLSEVGVGPXSHTLAG-
MAV_2957|M.avium_104 PPADVIVCCKFRDRRLDRAIVERLAPGGLLAIAVLSEVGAGPGPFRAAPG
MMAR_2640|M.marinum_M PPVDVIVCHNFRDRRLDAAIIDRLAPGGLVALVALSEVGAAAGTYRAAPG
MUL_3115|M.ulcerans_Agy99 PPVDLIVCHNFRDRRLDAAIIERLAPGGLVALVALSEVGAAAGTYRAAPG
MSMEG_4544|M.smegmatis_MC2_155 PPVDVVLCHRFRDPRLYEALRARLAPGGLLAICVLSEVGAEAGRFRAPAG
Mflv_3243|M.gilvum_PYR-GCK GPADVVLCSMFRDPRLDAALVERLAPGGLLAVSALSEVGAAPGRFRAGPG
Mvan_2956|M.vanbaalenii_PYR-1 DPVDVLLCNMFRDPRLDGPIVDRLAVGGVLAISALSEVGAAPGRFRARPG
*.*:::* :** ** .: *** **::*: .*****. . .
TH_2727|M.thermoresistible__bu ------------PAPQARSRAWPVAGNRSS--------------------
MAV_2957|M.avium_104 ELTAAFADLQPIAAGEADGQAWLLARASQSEPMVERR-------------
MMAR_2640|M.marinum_M ELSAAFAELDPIAAGEGDGRAWLLARA-----------------------
MUL_3115|M.ulcerans_Agy99 ELSTAFAELDPIAAGEGDGRAWLLARA-----------------------
MSMEG_4544|M.smegmatis_MC2_155 ELRAHFGALQVIAENERDGEAWLLAR------------------------
Mflv_3243|M.gilvum_PYR-GCK ELLRAFGAVDVIEHGEADGQAWLLGRRRGLPQRAPQAHRDPDDRPAHPDE
Mvan_2956|M.vanbaalenii_PYR-1 ELVAAFGSLELITHGEEAGQAWLLARRR----------------------
: ..** :.
TH_2727|M.thermoresistible__bu --
MAV_2957|M.avium_104 --
MMAR_2640|M.marinum_M --
MUL_3115|M.ulcerans_Agy99 --
MSMEG_4544|M.smegmatis_MC2_155 --
Mflv_3243|M.gilvum_PYR-GCK LL
Mvan_2956|M.vanbaalenii_PYR-1 --