For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_2648 (-)

annotation: putative phosphotransferase enzyme family protein, putative
coordinates: 898947 - 900017
length: 357

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2648--100% (357)putative phosphotransferase enzyme family protein, putative
M. thermoresistible (build 8)TH_0687-5e-2932.39% (284) CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)TH_2763-7e-2230.22% (321) PUTATIVE putative aminoglycoside phosphotransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3193-4e-3030.65% (310) hypothetical protein Mb3193
M. gilvum PYR-GCKMflv_4497-3e-2529.43% (316) aminoglycoside phosphotransferase
M. tuberculosis H37RvRv3168-3e-2930.65% (310) hypothetical protein Rv3168
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4482-2e-2529.83% (352) putative phosphotransferase
M. marinum MMMAR_1393-2e-2729.68% (310) hypothetical protein MMAR_1393
M. avium 104MAV_5060-1e-4234.33% (335) putative phosphotransferase
M. smegmatis MC2 155MSMEG_4981-4e-7643.10% (348) phosphotransferase enzyme family protein, putative
M. ulcerans Agy99MUL_2483-2e-2629.35% (310) hypothetical protein MUL_2483
M. vanbaalenii PYR-1Mvan_1869-5e-2730.00% (330) aminoglycoside phosphotransferase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1393|M.marinum_M               -MANETP-VEDVAHLQRSSRDMTTLPAVMARWLAGVLPGNAAP---EVTV
MUL_2483|M.ulcerans_Agy99           -MANETP-VEDVAHLQRSSRDMTTLPAVMARWLAGVLPGNAAP---EVTV
Mb3193|M.bovis_AF2122/97            -MANEPA-IGAIDRLQRSSRDVTTLPAVISRWLSSVLPGGAAP---EVTV
Rv3168|M.tuberculosis_H37Rv         -MANEPA-IGAIDRLQRSSRDVTTLPAVISRWLSSVLPGGAAP---EVTV
Mflv_4497|M.gilvum_PYR-GCK          -MTSEPA-VDNVDRLQRSSRDLSDVPAALSRWLSTKLPGVTPDAPVDITV
Mvan_1869|M.vanbaalenii_PYR-1       -MTSEPA-VDNVDRLQRSSRDMSNVPAALSQWLSTLIPDITP----EITV
MAB_4482|M.abscessus_ATCC_1997      -MTEQTATHEDVARPAESQRDPETLRGALTDWISGQLPADAAL---SVDH
TH_2648|M.thermoresistible__bu      ---------MATPGTEDIRPTEAELPARLEPVIHRRLPDTAGTR----IT
MSMEG_4981|M.smegmatis_MC2_155      ----------------MVRIAADELPGAVEAVVRKRLPGAENAR----VA
MAV_5060|M.avium_104                MLHQLDKKNWDYTMALLNKLDSATLAGRLSPWLADTLAVSGEVT---LNN
                                                            : . :   :   :.            

MMAR_1393|M.marinum_M               ESGVDSTGMSSETIILTARWHEDHRPVQQKLVARVAPAAGDVPVFPSYRL
MUL_2483|M.ulcerans_Agy99           ESGVDSTGMSSETIILTARWHEDHRPVQQKLVARVAPAAGDVPVFPSYRL
Mb3193|M.bovis_AF2122/97            ESGVDSTGMSSETIILTARRQQDGRSIQQKLVARVAPAAEDVPVFPTYRL
Rv3168|M.tuberculosis_H37Rv         ESGVDSTGMSSETIILTARWQQDGRSIQQKLVARVAPAAEDVPVFPTYRL
Mflv_4497|M.gilvum_PYR-GCK          EDGIDANGMSSETILLRGRWSDGGDPVEHRWVARVAPTDADIPVFEHYRL
Mvan_1869|M.vanbaalenii_PYR-1       ESGIDANGMSSETILLRGRWLQAGDPVEQRWVARVAPAEADIPVFEHYRL
MAB_4482|M.abscessus_ATCC_1997      AELPSANGMSSETILADAQWTENGQRTAHRLVIRTAPQPDSSPVFPSYDM
TH_2648|M.thermoresistible__bu      NWRAAERGMSTETFLFDLQRDGPDGPVTVRRLVFRRPPA--VSLFPDYDL
MSMEG_4981|M.smegmatis_MC2_155      NWSASTAGFSTETYLFDV--EGLDACDTLG-LVFRRPPE--YQILPGYDL
MAV_5060|M.avium_104                IEIPTASGMSSETVLFEAVWDNDGQRNTRGLVVRIPPSG--EGLFPDYDI
                                           *:*:** :                :    *      ::  * :

MMAR_1393|M.marinum_M               DHQFEVIKLVGELSDVPVPRVRWMEPTGEVLGTPFFLMDYVEGVVPPDVM
MUL_2483|M.ulcerans_Agy99           DHRFEVIKLVGELSDVPVPRVRWMVPTGEVLGTPFFLMDYVEGVVPPDVM
Mb3193|M.bovis_AF2122/97            DHQFEVIRLVGELTDVPVPRVRWIETTGDVLGTPFFLMDYVEGVVPPDVM
Rv3168|M.tuberculosis_H37Rv         DHQFEVIRLVGELTDVPVPRVRWIETTGDVLGTPFFLMDYVEGVVPPDVM
Mflv_4497|M.gilvum_PYR-GCK          DHQHEVMRLVAESTDVAVPAVRWLEDTGDVLGRPFFLMDRVDGVVPPDVM
Mvan_1869|M.vanbaalenii_PYR-1       DHQHEVMRLVAELTDVAVPPVRWLERRGDVLGRPFFLMDRVEGIVPPDVM
MAB_4482|M.abscessus_ATCC_1997      RRQFDVMDTLGRHSSAVVPPVRWYCDDTAVLGGEFFVMDRVDGDVPPDRM
TH_2648|M.thermoresistible__bu      LRQVLVMNRLRDT-EVPVPTVCWLDRDGMELGTPYYVMEQIPTIGSPGDF
MSMEG_4981|M.smegmatis_MC2_155      RRQYLVMQRLAPS-PVPVPGVRWIDADGSDLGTPYLVMDRIDHVVGVSDV
MAV_5060|M.avium_104                AREGRVMAVVAAHSEAAVPGVVAAELTGEVLGGPFLLLERAYGRVPSDDP
                                     :.  *:  :     . ** *         **  : :::        .  

MMAR_1393|M.marinum_M               PYTFGNNWFADAPAERQRELQDATVGLLAMLHSIPKPQDTFGFLSDG-PS
MUL_2483|M.ulcerans_Agy99           PYTFGNNWFADAPAERQRELQDATVGLLAMLHSIPKPQDTFGFLSDG-PS
Mb3193|M.bovis_AF2122/97            PYTFGDNWFADAPAERQRQLQDATVAALATLHSIPNAQNTFSFLTQG-RT
Rv3168|M.tuberculosis_H37Rv         PYTFGDNWFADAPAERQRQLQDATVAALATLHSIPNAQNTFSFLTQG-RT
Mflv_4497|M.gilvum_PYR-GCK          PYTFGDNWLYDASPEQQRALQDRTVEVLAALHSIPDAQRTFGFLQEIDPP
Mvan_1869|M.vanbaalenii_PYR-1       PYTFGDNWLFDATAEQQRQLQDRTVEVLAKLHSIPNAQQVFGFLQDVDPP
MAB_4482|M.abscessus_ATCC_1997      PYTFG-SWVTEASEADRRKMQRLTVDQLARIHAAPVER--FAFLNDA-RE
TH_2648|M.thermoresistible__bu      PSYHCAGMYFDATSQQRTTMWTGCVRAMADVHTLDWRALRLDALLMP-DR
MSMEG_4981|M.smegmatis_MC2_155      PPYHQHGLFAETDDAGRAALWNGCVDMIAAVHRLDPQQYRLGFLGAS-TP
MAV_5060|M.avium_104                PFVTG-GWVVDLTPEQRATMFDNALRTIAAIQKVDPAAVGLDDLGRS-GV
                                    *     .   :     :  :    :  :* ::        :  *      

MMAR_1393|M.marinum_M               GDTALRRHFDWVRSWYDFAVPGIGNSALIERTFQWLQEHWPSE----VAA
MUL_2483|M.ulcerans_Agy99           GDTALRRHFDWVRSWYDFAVPGIGNSALIERTFQWLQEHWPSE----VAA
Mb3193|M.bovis_AF2122/97            SDTTLHRHFNWVRSWYDFAVEGIGRSPLLERTFEWLQSHWPDD----AAA
Rv3168|M.tuberculosis_H37Rv         SDTTLHRHFNWVRSWYDFAVEGIGRSPLLERTFEWLQSHWPDD----AAA
Mflv_4497|M.gilvum_PYR-GCK          GETALHRHFGWLTRWYAFSSADLGSSPLVERAISWLEEHFPHD----VAA
Mvan_1869|M.vanbaalenii_PYR-1       GPTALHRHFGWLKNWYEFSVPDIGRSPLVERALAWLEDRFPED----VAA
MAB_4482|M.abscessus_ATCC_1997      GETGLDAHVRRTHEFYEWVRGDGPTIPLIDRGFEWLRENWPEESLSGVGR
TH_2648|M.thermoresistible__bu      GRHPLEQVVDYYTDALHWASDGDP-RPELAAAAEWLRRHLYEP-------
MSMEG_4981|M.smegmatis_MC2_155      G-----ALVDFLRHAIGWAYGDNPVHPTFTRALHWLRAHLYEP-------
MAV_5060|M.avium_104                GKTVLHREVEYWRNFYLWAADGRP-NPTIDAAFEKLSQAIPTQT------
                                    .       .        :   .    . .      *              

MMAR_1393|M.marinum_M               REPVLLWGDARVGNVLYR-DFRPVAVLDWEMVTLGPRELDVAWMIFAHMV
MUL_2483|M.ulcerans_Agy99           REPVLLWGDARVGNVLYR-DFRPVAVLDWEMVTLGPRELDVAWMIFAHMV
Mb3193|M.bovis_AF2122/97            REPVLLWGDARVGNVLYR-DFQPVAVLDWEMVALGPRELDVAWMIFAHRV
Rv3168|M.tuberculosis_H37Rv         REPVLLWGDARVGNVLYR-DFQPVAVLDWEMVALGPRELDVAWMIFAHRV
Mflv_4497|M.gilvum_PYR-GCK          SEPVLVWGDSRIGNVIYR-DFRPVAVLDWEMATIGPREFDLAWISFAHMV
Mvan_1869|M.vanbaalenii_PYR-1       AEPVLVWGDSRIGNVIYQ-DFSPVAVLDWEMATVGPREFDVAWISFAHMV
MAB_4482|M.abscessus_ATCC_1997      PIDVVSWGDSRPGNVIYR-DFEPVALLDWEMASVGPRELDLGWIIFLHRF
TH_2648|M.thermoresistible__bu      EHLALCWGDSRLSNILYGEDFAVNAVVDWEIAYIGDHEADLAWFLFIDWA
MSMEG_4981|M.smegmatis_MC2_155      EHVGLCWGDSRMSNVLYRPDLTPVAALDWEIAYLGDQAADLSWLFMTDWI
MAV_5060|M.avium_104                GPLVISWGDARFGNLMFADDLTVSGVFDWEMATLGPSEVDFGYFLFFDRV
                                        : ***:* .*:::  *:   . .***:. :*    *..:: : .  

MMAR_1393|M.marinum_M               FEELAGLATLPGLPTVMREDDVRRTYQRLTGTQLGDLHWFYVYSGVMWAC
MUL_2483|M.ulcerans_Agy99           FEELAGLATLPGLPTVMREDDVRRTYQRLTGTQLGDLHWFYVYSGVMWAC
Mb3193|M.bovis_AF2122/97            FQELAGLATLPGLPEVMREDDVRATYQALTGVELGDLHWFYVYSGVMWAC
Rv3168|M.tuberculosis_H37Rv         FQELAGLATLPGLPEVMREDDVRATYQALTGVELGDLHWFYVYSGVMWAC
Mflv_4497|M.gilvum_PYR-GCK          FQELTKLAGLPGMPDFLREDDVRDTYRKLTGVEVGDLHWFHVYSAVVWCC
Mvan_1869|M.vanbaalenii_PYR-1       FQELTKLAGLPGMPDFLREDDVRETYRELTGVEIGDLHWFHVYSAVVWCC
MAB_4482|M.abscessus_ATCC_1997      FQDLAEVATLPGLPDFCKREDIAAEYAALTGHHAADLDFYTAYAALQHAV
TH_2648|M.thermoresistible__bu      FSEYEGTPRLPGTP---GRDETIELYQRLSGLPVRNLRYNELLAVLALSV
MSMEG_4981|M.smegmatis_MC2_155      SSPLPGNAPAPGTP---SREQTIARYERAVGRSVGNLAFGDVSAPLLLAV
MAV_5060|M.avium_104                YSSGLGLPRLDGFP---ERAHAIARFEELTGRRTENLEWYEAWGALRGAI
                                     .     .   * *    . .    :    *    :* :    . :  . 

MMAR_1393|M.marinum_M               VFMRTGARRVHFGEVEKPDDVESLFYHAGLMKRLIGDER-----------
MUL_2483|M.ulcerans_Agy99           VFMRTGARRVHFGEVEKPDDVESLFYHAGLMKRLIGDER-----------
Mb3193|M.bovis_AF2122/97            VFMRTGARRVHFGEIEKPDDVESLFYHAGLMKHLLGEEH-----------
Rv3168|M.tuberculosis_H37Rv         VFMRTGARRVHFGEIEKPDDVESLFYHAGLMKHLLGEEH-----------
Mflv_4497|M.gilvum_PYR-GCK          VFMRTGTRRVHFGEIERPDDIESLFYHASLLKRLIGEAD-----------
Mvan_1869|M.vanbaalenii_PYR-1       VFMRTGARRVHFGEIERPADIETLFYHASLLKRLIGETD-----------
MAB_4482|M.abscessus_ATCC_1997      IMARIQMRAMAFGQAQMPDDPDDLILHRATLEKMLNGTYWAGVKA-----
TH_2648|M.thermoresistible__bu      PVTRLETKLRSDGLLAEGFDLLGFCVER--ARQLLG--------------
MSMEG_4981|M.smegmatis_MC2_155      ALVRLNRRFDIP-----GVDLADVCARR--IEFVLDS-------------
MAV_5060|M.avium_104                LLQRVGNLLISQGLLPPEADMPFNNPASQVLASLLELPPPAGQTGWITGN
                                     . *               *             ::               

MMAR_1393|M.marinum_M               -
MUL_2483|M.ulcerans_Agy99           -
Mb3193|M.bovis_AF2122/97            -
Rv3168|M.tuberculosis_H37Rv         -
Mflv_4497|M.gilvum_PYR-GCK          -
Mvan_1869|M.vanbaalenii_PYR-1       -
MAB_4482|M.abscessus_ATCC_1997      -
TH_2648|M.thermoresistible__bu      -
MSMEG_4981|M.smegmatis_MC2_155      -
MAV_5060|M.avium_104                R