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VRIAADELPGAVEAVVRKRLPGAENARVANWSASTAGFSTETYLFDVEGLDACDTLGLVFRRPPEYQILP GYDLRRQYLVMQRLAPSPVPVPGVRWIDADGSDLGTPYLVMDRIDHVVGVSDVPPYHQHGLFAETDDAGR AALWNGCVDMIAAVHRLDPQQYRLGFLGASTPGALVDFLRHAIGWAYGDNPVHPTFTRALHWLRAHLYEP EHVGLCWGDSRMSNVLYRPDLTPVAALDWEIAYLGDQAADLSWLFMTDWISSPLPGNAPAPGTPSREQTI ARYERAVGRSVGNLAFGDVSAPLLLAVALVRLNRRFDIPGVDLADVCARRIEFVLDS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4981 | - | - | 100% (338) | phosphotransferase enzyme family protein, putative |
| M. smegmatis MC2 155 | MSMEG_2042 | - | 2e-31 | 33.12% (314) | phosphotransferase enzyme family protein |
| M. smegmatis MC2 155 | MSMEG_2069 | - | 2e-16 | 30.19% (265) | phosphotransferase enzyme family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3193 | - | 4e-27 | 29.79% (329) | hypothetical protein Mb3193 |
| M. gilvum PYR-GCK | Mflv_4497 | - | 7e-29 | 31.55% (336) | aminoglycoside phosphotransferase |
| M. tuberculosis H37Rv | Rv3168 | - | 4e-27 | 29.79% (329) | hypothetical protein Rv3168 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4482 | - | 9e-31 | 32.44% (336) | putative phosphotransferase |
| M. marinum M | MMAR_1393 | - | 1e-28 | 32.82% (262) | hypothetical protein MMAR_1393 |
| M. avium 104 | MAV_4058 | - | 1e-30 | 31.73% (312) | phosphotransferase enzyme family protein |
| M. thermoresistible (build 8) | TH_2648 | - | 2e-76 | 43.10% (348) | PUTATIVE putative phosphotransferase enzyme family protein, |
| M. ulcerans Agy99 | MUL_2483 | - | 8e-28 | 32.44% (262) | hypothetical protein MUL_2483 |
| M. vanbaalenii PYR-1 | Mvan_1869 | - | 3e-25 | 32.45% (302) | aminoglycoside phosphotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3193|M.bovis_AF2122/97 MANEPA-IGAIDRLQRSSRDVTTLPAVISRWLSSVLPGGAAP---EVTVE
Rv3168|M.tuberculosis_H37Rv MANEPA-IGAIDRLQRSSRDVTTLPAVISRWLSSVLPGGAAP---EVTVE
MAV_4058|M.avium_104 MATEPA-VDNVDRLQRSSRDVTTVPAVMSRWLSTVLPEGAEP---EVTVE
MMAR_1393|M.marinum_M MANETP-VEDVAHLQRSSRDMTTLPAVMARWLAGVLPGNAAP---EVTVE
MUL_2483|M.ulcerans_Agy99 MANETP-VEDVAHLQRSSRDMTTLPAVMARWLAGVLPGNAAP---EVTVE
Mflv_4497|M.gilvum_PYR-GCK MTSEPA-VDNVDRLQRSSRDLSDVPAALSRWLSTKLPGVTPDAPVDITVE
Mvan_1869|M.vanbaalenii_PYR-1 MTSEPA-VDNVDRLQRSSRDMSNVPAALSQWLSTLIPDITP----EITVE
MAB_4482|M.abscessus_ATCC_1997 MTEQTATHEDVARPAESQRDPETLRGALTDWISGQLPADAAL---SVDHA
MSMEG_4981|M.smegmatis_MC2_155 ---------------MVRIAADELPGAVEAVVRKRLPGAENAR----VAN
TH_2648|M.thermoresistible__bu --------MATPGTEDIRPTEAELPARLEPVIHRRLPDTAGTR----ITN
: . : : :*
Mb3193|M.bovis_AF2122/97 SGVDSTGMSSETIILTARRQQDGRSIQQKLVARVAPAAEDVPVFPTYRLD
Rv3168|M.tuberculosis_H37Rv SGVDSTGMSSETIILTARWQQDGRSIQQKLVARVAPAAEDVPVFPTYRLD
MAV_4058|M.avium_104 SGVDSTGMSSETIILTARWRQDERPTEQKLVARVAPTAEDVQVFPTYRLD
MMAR_1393|M.marinum_M SGVDSTGMSSETIILTARWHEDHRPVQQKLVARVAPAAGDVPVFPSYRLD
MUL_2483|M.ulcerans_Agy99 SGVDSTGMSSETIILTARWHEDHRPVQQKLVARVAPAAGDVPVFPSYRLD
Mflv_4497|M.gilvum_PYR-GCK DGIDANGMSSETILLRGRWSDGGDPVEHRWVARVAPTDADIPVFEHYRLD
Mvan_1869|M.vanbaalenii_PYR-1 SGIDANGMSSETILLRGRWLQAGDPVEQRWVARVAPAEADIPVFEHYRLD
MAB_4482|M.abscessus_ATCC_1997 ELPSANGMSSETILADAQWTENGQRTAHRLVIRTAPQPDSSPVFPSYDMR
MSMEG_4981|M.smegmatis_MC2_155 WSASTAGFSTETYLFDV--EGLDACDTLG-LVFRRPPE--YQILPGYDLR
TH_2648|M.thermoresistible__bu WRAAERGMSTETFLFDLQRDGPDGPVTVRRLVFRRPPA--VSLFPDYDLL
*:*:** : : * :: * :
Mb3193|M.bovis_AF2122/97 HQFEVIRLVGELTDVPVPRVRWIETTGDVLGTPFFLMDYVEGVVPPDVMP
Rv3168|M.tuberculosis_H37Rv HQFEVIRLVGELTDVPVPRVRWIETTGDVLGTPFFLMDYVEGVVPPDVMP
MAV_4058|M.avium_104 HQFEVIRKVGELTDVPVPRVRWLENTGEVLGTPFFVMDYVDGLVPPDVMP
MMAR_1393|M.marinum_M HQFEVIKLVGELSDVPVPRVRWMEPTGEVLGTPFFLMDYVEGVVPPDVMP
MUL_2483|M.ulcerans_Agy99 HRFEVIKLVGELSDVPVPRVRWMVPTGEVLGTPFFLMDYVEGVVPPDVMP
Mflv_4497|M.gilvum_PYR-GCK HQHEVMRLVAESTDVAVPAVRWLEDTGDVLGRPFFLMDRVDGVVPPDVMP
Mvan_1869|M.vanbaalenii_PYR-1 HQHEVMRLVAELTDVAVPPVRWLERRGDVLGRPFFLMDRVEGIVPPDVMP
MAB_4482|M.abscessus_ATCC_1997 RQFDVMDTLGRHSSAVVPPVRWYCDDTAVLGGEFFVMDRVDGDVPPDRMP
MSMEG_4981|M.smegmatis_MC2_155 RQYLVMQRLAPS-PVPVPGVRWIDADGSDLGTPYLVMDRIDHVVGVSDVP
TH_2648|M.thermoresistible__bu RQVLVMNRLRDT-EVPVPTVCWLDRDGMELGTPYYVMEQIPTIGSPGDFP
:: *: : . ** * * ** : :*: : . .*
Mb3193|M.bovis_AF2122/97 YTFGDNWFADAPAERQRQLQDATVAALATLHSIPNAQNTFSFLTQG-RTS
Rv3168|M.tuberculosis_H37Rv YTFGDNWFADAPAERQRQLQDATVAALATLHSIPNAQNTFSFLTQG-RTS
MAV_4058|M.avium_104 YTFGGNWFADAPAERQRELQDATVGVLAKLHSIPNAANTFGFLTEG-QTG
MMAR_1393|M.marinum_M YTFGNNWFADAPAERQRELQDATVGLLAMLHSIPKPQDTFGFLSDG-PSG
MUL_2483|M.ulcerans_Agy99 YTFGNNWFADAPAERQRELQDATVGLLAMLHSIPKPQDTFGFLSDG-PSG
Mflv_4497|M.gilvum_PYR-GCK YTFGDNWLYDASPEQQRALQDRTVEVLAALHSIPDAQRTFGFLQEIDPPG
Mvan_1869|M.vanbaalenii_PYR-1 YTFGDNWLFDATAEQQRQLQDRTVEVLAKLHSIPNAQQVFGFLQDVDPPG
MAB_4482|M.abscessus_ATCC_1997 YTFG-SWVTEASEADRRKMQRLTVDQLARIHAAP--VERFAFLNDA-REG
MSMEG_4981|M.smegmatis_MC2_155 PYHQHGLFAETDDAGRAALWNGCVDMIAAVHRLDPQQYRLGFLGAS-TPG
TH_2648|M.thermoresistible__bu SYHCAGMYFDATSQQRTTMWTGCVRAMADVHTLDWRALRLDALLMP-DRG
. . :: : : * :* :* : * .
Mb3193|M.bovis_AF2122/97 DTTLHRHFNWVRSWYDFAVEGIGRSPLLERTFEWLQSHWPDDAAAREP--
Rv3168|M.tuberculosis_H37Rv DTTLHRHFNWVRSWYDFAVEGIGRSPLLERTFEWLQSHWPDDAAAREP--
MAV_4058|M.avium_104 DTALRRHFNWVRSWYDFAVPDIGRSPLLERTFDWLEAHWPAAADAAEP--
MMAR_1393|M.marinum_M DTALRRHFDWVRSWYDFAVPGIGNSALIERTFQWLQEHWPSEVAAREP--
MUL_2483|M.ulcerans_Agy99 DTALRRHFDWVRSWYDFAVPGIGNSALIERTFQWLQEHWPSEVAAREP--
Mflv_4497|M.gilvum_PYR-GCK ETALHRHFGWLTRWYAFSSADLGSSPLVERAISWLEEHFPHDVAASEP--
Mvan_1869|M.vanbaalenii_PYR-1 PTALHRHFGWLKNWYEFSVPDIGRSPLVERALAWLEDRFPEDVAAAEP--
MAB_4482|M.abscessus_ATCC_1997 ETGLDAHVRRTHEFYEWVRGDGPTIPLIDRGFEWLRENWPEESLSGVGRP
MSMEG_4981|M.smegmatis_MC2_155 -----ALVDFLRHAIGWAYGDNPVHPTFTRALHWLRAHLYEPEHVGLC--
TH_2648|M.thermoresistible__bu RHPLEQVVDYYTDALHWASDGDP-RPELAAAAEWLRRHLYEPEHLALC--
. : . . . **. .
Mb3193|M.bovis_AF2122/97 --VLLWGDARVGNVLYR-DFQPVAVLDWEMVALGPRELDVAWMIFAHRVF
Rv3168|M.tuberculosis_H37Rv --VLLWGDARVGNVLYR-DFQPVAVLDWEMVALGPRELDVAWMIFAHRVF
MAV_4058|M.avium_104 --VLLWGDARVGNVLYR-DFVPVAVLDWEMVTLGPRELDVAWMIFAHMVF
MMAR_1393|M.marinum_M --VLLWGDARVGNVLYR-DFRPVAVLDWEMVTLGPRELDVAWMIFAHMVF
MUL_2483|M.ulcerans_Agy99 --VLLWGDARVGNVLYR-DFRPVAVLDWEMVTLGPRELDVAWMIFAHMVF
Mflv_4497|M.gilvum_PYR-GCK --VLVWGDSRIGNVIYR-DFRPVAVLDWEMATIGPREFDLAWISFAHMVF
Mvan_1869|M.vanbaalenii_PYR-1 --VLVWGDSRIGNVIYQ-DFSPVAVLDWEMATVGPREFDVAWISFAHMVF
MAB_4482|M.abscessus_ATCC_1997 IDVVSWGDSRPGNVIYR-DFEPVALLDWEMASVGPRELDLGWIIFLHRFF
MSMEG_4981|M.smegmatis_MC2_155 -----WGDSRMSNVLYRPDLTPVAALDWEIAYLGDQAADLSWLFMTDWIS
TH_2648|M.thermoresistible__bu -----WGDSRLSNILYGEDFAVNAVVDWEIAYIGDHEADLAWFLFIDWAF
***:* .*::* *: * :***:. :* : *:.*: : .
Mb3193|M.bovis_AF2122/97 QELAGLATLPGLPEVMREDDVRATYQALTGVELGDLHWFYVYSGVMWACV
Rv3168|M.tuberculosis_H37Rv QELAGLATLPGLPEVMREDDVRATYQALTGVELGDLHWFYVYSGVMWACV
MAV_4058|M.avium_104 QELAGLATLPGLPGVMREDDVRATYERLTGVEIGDLHWFYVYSGVMWACV
MMAR_1393|M.marinum_M EELAGLATLPGLPTVMREDDVRRTYQRLTGTQLGDLHWFYVYSGVMWACV
MUL_2483|M.ulcerans_Agy99 EELAGLATLPGLPTVMREDDVRRTYQRLTGTQLGDLHWFYVYSGVMWACV
Mflv_4497|M.gilvum_PYR-GCK QELTKLAGLPGMPDFLREDDVRDTYRKLTGVEVGDLHWFHVYSAVVWCCV
Mvan_1869|M.vanbaalenii_PYR-1 QELTKLAGLPGMPDFLREDDVRETYRELTGVEIGDLHWFHVYSAVVWCCV
MAB_4482|M.abscessus_ATCC_1997 QDLAEVATLPGLPDFCKREDIAAEYAALTGHHAADLDFYTAYAALQHAVI
MSMEG_4981|M.smegmatis_MC2_155 SPLPGNAPAPGTP---SREQTIARYERAVGRSVGNLAFGDVSAPLLLAVA
TH_2648|M.thermoresistible__bu SEYEGTPRLPGTP---GRDETIELYQRLSGLPVRNLRYNELLAVLALSVP
. . ** * .:: * * :* : : : .
Mb3193|M.bovis_AF2122/97 FMRTGARRVHFGEIEKPDDVESLFYHAGLMKHLLGEEH------
Rv3168|M.tuberculosis_H37Rv FMRTGARRVHFGEIEKPDDVESLFYHAGLMKHLLGEEH------
MAV_4058|M.avium_104 FMRTGARRVHFGETEKPDDVESLFYHAGLMKRLIGEE-------
MMAR_1393|M.marinum_M FMRTGARRVHFGEVEKPDDVESLFYHAGLMKRLIGDER------
MUL_2483|M.ulcerans_Agy99 FMRTGARRVHFGEVEKPDDVESLFYHAGLMKRLIGDER------
Mflv_4497|M.gilvum_PYR-GCK FMRTGTRRVHFGEIERPDDIESLFYHASLLKRLIGEAD------
Mvan_1869|M.vanbaalenii_PYR-1 FMRTGARRVHFGEIERPADIETLFYHASLLKRLIGETD------
MAB_4482|M.abscessus_ATCC_1997 MARIQMRAMAFGQAQMPDDPDDLILHRATLEKMLNGTYWAGVKA
MSMEG_4981|M.smegmatis_MC2_155 LVRLNRRFDIP-----GVDLADVCARR--IEFVLDS--------
TH_2648|M.thermoresistible__bu VTRLETKLRSDGLLAEGFDLLGFCVER--ARQLLG---------
. * : * . . . ::.