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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_2635 | - | - | 100% (742) | ABC transporter related |
M. thermoresistible (build 8) | TH_3745 | - | 2e-71 | 32.11% (601) | PUTATIVE ABC transporter related |
M. thermoresistible (build 8) | TH_3650 | - | 1e-68 | 30.98% (594) | PUTATIVE ABC transporter ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0200 | - | 6e-88 | 34.25% (616) | drugs-transport transmembrane ATP-binding protein ABC |
M. gilvum PYR-GCK | Mflv_1747 | - | 0.0 | 78.92% (612) | ABC transporter related |
M. tuberculosis H37Rv | Rv0194 | - | 3e-89 | 34.42% (616) | drugs-transport transmembrane ATP-binding protein ABC |
M. leprae Br4923 | MLBr_01113 | - | 3e-68 | 28.30% (622) | putative ABC transporter, ATP-binding component |
M. abscessus ATCC 19977 | MAB_1415c | - | 1e-67 | 31.16% (584) | ABC transporter ATP-binding protein |
M. marinum M | MMAR_5223 | - | 3e-82 | 34.19% (620) | drug-transport transmembrane ATP-binding protein ABC |
M. avium 104 | MAV_1420 | - | 2e-69 | 31.87% (524) | ABC transporter |
M. smegmatis MC2 155 | MSMEG_5660 | - | 0.0 | 79.54% (611) | ABC transporter ATP-binding protein |
M. ulcerans Agy99 | MUL_4011 | - | 5e-71 | 29.88% (646) | transmembrane ATP-binding protein ABC transporter |
M. vanbaalenii PYR-1 | Mvan_5006 | - | 0.0 | 78.82% (609) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb0200|M.bovis_AF2122/97 ---------------------------MRTNCWWRLSGYVMRHRRDLLLG Rv0194|M.tuberculosis_H37Rv ---------------------------MRTNCWWRLSGYVMRHRRDLLLG MMAR_5223|M.marinum_M ---------------------------MRTNWWGRLSRYVLRYRRDLLLG Mflv_1747|M.gilvum_PYR-GCK -----MADSRTDSLHAAPAIGPPPSRVRPSSDLWRMMPYLLPYRGRWIVM Mvan_5006|M.vanbaalenii_PYR-1 -----MADTGFDSLRAAPSIGPPPKRVKPSSDLWRMMPYLLPYRGRWIVM MSMEG_5660|M.smegmatis_MC2_155 MVVTEPPQSHRDGLRSAPAIAPAPERKRAATDLRRLLPYLLPYRARWVTM TH_2635|M.thermoresistible__bu --------VVTGRLHEAAKIAPPPERSWVGADLWRLLPYLMPYRARWTAM MLBr_01113|M.leprae_Br4923 -------MTMAT-------APA-TRSCDFYCTIRRLLKQLVPQRRLSLTV MUL_4011|M.ulcerans_Agy99 -------MTAALNQRPRGGAPAPTRSRDFWGSATRLVKRLAPQRRRSLAV MAV_1420|M.avium_104 -------MTTTTRPAPP--APA-GRSRDFWGSAARLVKQLAPQRRTAIAV MAB_1415c|M.abscessus_ATCC_199 --------------------------MPQGQLRALLPRYVRPYRGLIAVV : : * Mb0200|M.bovis_AF2122/97 FGAALAGTVIAVLVPLVT----KRVIDDAVAA-DHRPLAPWAVVLVAAA- Rv0194|M.tuberculosis_H37Rv FGAALAGTVIAVLVPLVT----KRVIDDAIAA-DHRPLAPWAVVLVAAA- MMAR_5223|M.marinum_M LFASVVGTAITVMVPLVT----KRVIDNAIAP-DHRPLAPWALVLVAAA- Mflv_1747|M.gilvum_PYR-GCK IVVALASLAATISIPLMT----KAVIDGPVRQQDQQGLWLVGAAALGVG- Mvan_5006|M.vanbaalenii_PYR-1 IVVALASLAATISIPLMT----KAVIDGPVRHQDQQGLWLVGAAAVAVG- MSMEG_5660|M.smegmatis_MC2_155 VVVAIVSLGATIAIPLMT----KAVIDGPVRHQDSQGLWTLGAAAVGIG- TH_2635|M.thermoresistible__bu ITVAVVSLSATVAIPLMT----KAVIDGPVRQQDQQGLWILGSAAMAVG- MLBr_01113|M.leprae_Br4923 ITLGITGTAIGIIVPWVLGHTTDLLFNGVIGRQLPKGISKTQAVAAARTR MUL_4011|M.ulcerans_Agy99 IALGIVGTAIGVAVPRILGHAADLLFNGVIGRQLPAGITKAQAIAGARAR MAV_1420|M.avium_104 ITLGIAGTVIGVMVPRILGHATDLLFNGVVGRQLPAGISKAQAVAAARSR MAB_1415c|M.abscessus_ATCC_199 VTLQIISTLASLYLPTVN----AAIIDDGVAHGDTRTIARLGAVMLGVT- . : . : :* : :::. : : . Mb0200|M.bovis_AF2122/97 ------------------------------------GATYLLTYVRRYYG Rv0194|M.tuberculosis_H37Rv ------------------------------------GATYLLMYVRRYYG MMAR_5223|M.marinum_M ------------------------------------VAIYFMTFVRRHYG Mflv_1747|M.gilvum_PYR-GCK ------------------------------------VTEAVLWFIRRWLV Mvan_5006|M.vanbaalenii_PYR-1 ------------------------------------VTEAVLWFIRRWLV MSMEG_5660|M.smegmatis_MC2_155 ------------------------------------ISEAVLWFIRRWLV TH_2635|M.thermoresistible__bu ------------------------------------ISEAVLMFIRRWLV MLBr_01113|M.leprae_Br4923 GDNALADLLSGMNLVPGQGVDFVAVGRTLGLALSLYLVYTLLTWAQARLL MUL_4011|M.ulcerans_Agy99 GDNTFAELLSGMKVTPGQGVDFGAVVRTLALALALYLIASLLIWGQARLL MAV_1420|M.avium_104 GQNTFADLLSGMNVVPGRGVDFGAVARTLALALLLYLVSALLIWVQARLL MAB_1415c|M.abscessus_ATCC_199 ------------------------------------LVQITCSIGAVYFG Mb0200|M.bovis_AF2122/97 GRIAHLVQHDLRMDAFQALLRWDGRQQDRWSSGQLIVRTTNDLQLVQALL Rv0194|M.tuberculosis_H37Rv GRIAHLVQHDLRMDAFQALLRWDGRQQDRWSSGQLIVRTTNDLQLVQALL MMAR_5223|M.marinum_M GRIAHLVQHDLRVDAFATLMRWDGRQQDRWSSGQLIVRTTNDLELVQTLL Mflv_1747|M.gilvum_PYR-GCK ARATMGVEADIRKQLYARLQILPMSFHGRWQSGQLLSRIMNDLSTIRRFM Mvan_5006|M.vanbaalenii_PYR-1 ARATMGVEADIRKQLYARLQILPMSFHGQWQSGQLLSRIMNDLSTIRRFM MSMEG_5660|M.smegmatis_MC2_155 ARATMGVEADIRKDLYARLQILPMSFHGRWQSGQLLSRVMNDLSTIRRFM TH_2635|M.thermoresistible__bu ARATMGVEADIRKDLYARLQILPMSFHGRWQSGQLVSRVMNDLSTIRRLL MLBr_01113|M.leprae_Br4923 NVTVQRIMFALRSDVEDKVHRLPLSYCDTRQRGELLSRVTNDIDNLQSSL MUL_4011|M.ulcerans_Agy99 NVTVQRTVAALRADVEHKLHRLPLSYFDGRQRGELLSRVTNDIDNIQSSL MAV_1420|M.avium_104 NRTVQRTMVALRSAVEDKVHRLPLAYFDGRQRGELLSRVTNDIDNIQSSL MAB_1415c|M.abscessus_ATCC_199 SRTGMGFGRDMRSALFHHITGFSAEESARFGAPTLLTRTTNDVQQLQLLI :* : *: * **:. :: : Mb0200|M.bovis_AF2122/97 -FDVPNVLRHVLTLLLGVAVMTWLSVPLALLAVLLVPVIGLIAHRSRRLL Rv0194|M.tuberculosis_H37Rv -FDVPNVLRHVLTLLLGVAVMTWLSVPLALLAVLLVPVIGLIAHRSRRLL MMAR_5223|M.marinum_M -FDLPNVIRHLLTLLLCLAVMAWLSLPLALLVVLLVPLIGLVAHRSRRLL Mflv_1747|M.gilvum_PYR-GCK SFGLIFLMLNVLQITVVTVILLVMYWPLGVVVLVSIVPITLTVLHFQQEY Mvan_5006|M.vanbaalenii_PYR-1 SFGLIFLMLNVLQITVVTAILLAMYWPLGVVVLVSIVPITLTVLHFQQEY MSMEG_5660|M.smegmatis_MC2_155 SFGLVFLILNGLQITVVTAILLAMYWPLGVVVLVSIVPIAATVLHFEREY TH_2635|M.thermoresistible__bu SFGLVFLVLNGLQIAVVTSILLAMYWPLGVVALLSIVPITMTVLHFQRLY MLBr_01113|M.leprae_Br4923 SITLSQLLTSLLTVVAVLVVMVSVSPLLALVALLTVPMSLLATRAIAQRS MUL_4011|M.ulcerans_Agy99 SMTISQLVTAILTVVAVLSMMVWISPLLALITLLTVPLSLLVTRAITRRS MAV_1420|M.avium_104 SMTISQLLTSVLTVLTVLAMMLSISPLLAGITLLTVPLSLLATRVIVRRS MAB_1415c|M.abscessus_ATCC_199 QVTCTMLVTAPIMCVGGIAMAIHQNAGLSWLLMVSMPALGLANWYIVHSM . :: : : *. : :: : : Mb0200|M.bovis_AF2122/97 AAATHCAQEHKAAVTGVVDAAVCGIRVVKAFGQEERETVKLVMASRALYA Rv0194|M.tuberculosis_H37Rv AAATHCAQEHKAAVTGVVDAAVCGIRVVKAFGQEERETVKLVTASRALYA MMAR_5223|M.marinum_M AVATEAAQERNAVVTGVVDAAVSGIHVVKAFGQQSQETVKLTTAGRALYA Mflv_1747|M.gilvum_PYR-GCK TRLSRLAQDQAGHVATHVEEAALGLRVVKSFGREDYVYDRFDEQLTDLYD Mvan_5006|M.vanbaalenii_PYR-1 TRLSRLAQDQAGHVATHVEEAALGLRVIKSFGREDYVYERFDDQLTDLYD MSMEG_5660|M.smegmatis_MC2_155 TRLSRLAQDQTGHVATHVEESALGLRVVKSFGREDYVFDRFDEQATRLYD TH_2635|M.thermoresistible__bu TRLSRQAQDETGHVATHVEEAALGVRVVKSFGRERYSYDRFDEQATRLFR MLBr_01113|M.leprae_Br4923 QQLFVAQWTSAGRLNAHIEETYSGLTVVKTFGHQTAAREQFRNVNNDVYQ MUL_4011|M.ulcerans_Agy99 QRLFVAHWTSTGRLNAHIEETYSGFTVVKTFGHQAAAREQFHNLNDDVYQ MAV_1420|M.avium_104 QRLFVAQWTSVGRLNAHIEETYSGFTVVQTFGHRAAARDRFRALNDEVYR MAB_1415c|M.abscessus_ATCC_199 LPIFRRMQRLIDGINRVMREQLSGIRVVRAFTREAVERKRFSAAVAEVSE : : *. *:::* :. :: : Mb0200|M.bovis_AF2122/97 AQLRVARLNAHFGPLLQTLPALGQMAVFALGGWMAAQGSITVGTFVAFWA Rv0194|M.tuberculosis_H37Rv AQLRVARLNAHFGPLLQTLPALGQMAVFALGGWMAAQGSITVGTFVAFWA MMAR_5223|M.marinum_M ARVRVARLNAYFGPLLQSLPAFGQMAVLAVGGWMAAQGTITVGTFVAFWS Mflv_1747|M.gilvum_PYR-GCK TQIDRVSVSAKFWTLLEIIPNLTLIVVLGFGAYAAGHGHVTMGTLVAFIT Mvan_5006|M.vanbaalenii_PYR-1 TQVSRVSVSAKFWTLLEIIPNLTLIVVLGFGAYAAGHGYVTMGTLVAFIT MSMEG_5660|M.smegmatis_MC2_155 TQVARVGVSAKFWTLLEVIPNLTLIVVLGFGAYAAGHGYVTMGTLVAFIT TH_2635|M.thermoresistible__bu TQVGRVEVSARFWTLLEIIPNLTLIVVLGFGAYAAGTGLVTMGTLVAFIT MLBr_01113|M.leprae_Br4923 ASFSAQFFSGLVSPATMFISNLGYVVVAALGGLQVATGHITLGNIQAFIQ MUL_4011|M.ulcerans_Agy99 ASFGAQLLSALVQPATTFIGNLGYVAVAVMGGLQVATGQITLGSVQAFIQ MAV_1420|M.avium_104 ASFGAQFFSGLVAPATAVIGNLGYAAVAVLGGLQVATGQITLGNIQAFIQ MAB_1415c|M.abscessus_ATCC_199 AALAAGRWQALMLPATSLVINTSSVALIWFGGLRIDQGQMQVGSLVAFLS : . .. . . : .: .*. * : :*.. ** Mb0200|M.bovis_AF2122/97 CLTLLARPACDLAGMLTIAQQARAGAVRVLELIDSRPTLVDGTKPLSLEA Rv0194|M.tuberculosis_H37Rv CLTLLARPACDLAGMLTIAQQARAGAVRVLELIDSRPTLVDGTKPLSPEA MMAR_5223|M.marinum_M CLTLVSRPACDLAGMLTIAQQARTGAMRVFELIDSRPTLVDGTKQLPSST Mflv_1747|M.gilvum_PYR-GCK MMLSLVWPIASLGFLLSMTQESFTAANRIAEIFDAPREITDGPREQAPRG Mvan_5006|M.vanbaalenii_PYR-1 MMLSLVWPIASLGFLLSMTQESFTAANRIAEIFDAPREITDGPRDQAPRG MSMEG_5660|M.smegmatis_MC2_155 MMLSLVWPIASLGFLLSMTQESFTAANRIAEIFDAPREIVDGPITEAPRG TH_2635|M.thermoresistible__bu MMLSLVWPIASLGFLLSMTQESMTAANRIAEIFDAPIEITDGPITTPPRR MLBr_01113|M.leprae_Br4923 YVRQFNMPLSQVAGIYNTLQSGLASAERVFDLLDEPEELPDPMLALPPPH MUL_4011|M.ulcerans_Agy99 YVRQFNTPVSQVAAMYNSLQSGVASAERVFELLDEPEEAADPASALQPPV MAV_1420|M.avium_104 YVRQFNSPLSQLAGMYNTLQSGVASAERVFALLDEPEEPPDAPPEEKPTA MAB_1415c|M.abscessus_ATCC_199 YFLQILMSMMMLTMLAVMVPRASACAERITEVFDTTGAITAPADPVRVAD . . . : : . : * *: ::* Mb0200|M.bovis_AF2122/97 R----------LSLEFQRVSFGYVADRP----------VLREISLSVRAG Rv0194|M.tuberculosis_H37Rv R----------LSLEFQRVSFGYVADRP----------VLREISLSVRAG MMAR_5223|M.marinum_M P----------VSLAFEQASFGYAAEHP----------VLRGIDLSVRPG Mflv_1747|M.gilvum_PYR-GCK -----------GRLELVDVGFRFPD---------SDEWALRHVTVTVEPG Mvan_5006|M.vanbaalenii_PYR-1 -----------GRLEVVDVGFRFPDSA-------SGDWALRHVTVTVEPG MSMEG_5660|M.smegmatis_MC2_155 -----------GRLQLRDVGFKFPD---------SDEWVLRGVNLTVEPG TH_2635|M.thermoresistible__bu -----------GRLELRDVGFKFPDSGGVGASGGQDTWVLRHVTVTVEPG MLBr_01113|M.leprae_Br4923 ----GQVPRINGRVEFQQVSFAYRTGTP----------VIDDLSMVVEPG MUL_4011|M.ulcerans_Agy99 S-RTGRAPALTGRVEFERVNFAYHPGHP----------VIHDLSLVAEPG MAV_1420|M.avium_104 PGPAGRDAGGGGRVEFAHVSFAYRPGIR----------VIDDLSLVAEPG MAB_1415c|M.abscessus_ATCC_199 P---------YPTVEFTRAGFRYPGAER---------AVLEEISFTAQPG : . ..* : .: : . ...* Mb0200|M.bovis_AF2122/97 ETLAVVGAPGSGKSTLASLATRCYDVTQGAVRIGGQDVRELTLDSLRSAI Rv0194|M.tuberculosis_H37Rv ETLAVVGAPGSGKSTLASLATRCYDVTQGAVRIGGQDVRELTLDSLRSAI MMAR_5223|M.marinum_M ETLAVVGPPGSGKSTLALLAMRCYDVTAGAVRVGGHDVRDLTLDSLRSAI Mflv_1747|M.gilvum_PYR-GCK ETLALVGATGSGKSVLVGLLSRLYDVTEGEIRIDAQDIRELSLRALRETV Mvan_5006|M.vanbaalenii_PYR-1 ETLALVGATGSGKSVLAGLLSRLYDVTEGEIRIDAQDIRELSLDALRRTV MSMEG_5660|M.smegmatis_MC2_155 ETVALVGSTGSGKSVLAALFSRLYDVTEGQILIDGRDIRDLSLPALRRTV TH_2635|M.thermoresistible__bu ETLALVGPTGSGKSVLVSLLSRLYDVTEGQIRIDGIDIRELSLDALRRTV MLBr_01113|M.leprae_Br4923 STVAIVGPTGAGKTTLVNLLMRFYDVDSGQILIDGVDITTVSRHALRSRI MUL_4011|M.ulcerans_Agy99 STVAIVGPTGAGKTTLVNLLMRFYEVDSGRILVDGIDITTVSRQSLRSHI MAV_1420|M.avium_104 STVAIVGPTGAGKTTLVNLLMRFYDVDAGRISIDGVDIATMDRRALRSRI MAB_1415c|M.abscessus_ATCC_199 MITAIVGATGCGKSTLLNLIPRLHDVTTGSVRVGGNDVRRYDPEDLWTVM *:**..*.**:.* * * ::* * : :.. *: * : Mb0200|M.bovis_AF2122/97 GLVPEDAVLFSGTIGANIAYGRP--DATPEQIATAARAAHIEEFVNTLPD Rv0194|M.tuberculosis_H37Rv GLVPEDAVLFSGTIGANIAYGRP--DATPEQIATAARAAHIEEFVNTLPD MMAR_5223|M.marinum_M GLVPEQAILFSGTIGENISYGRS--NVTLEQITAAARAAHIDEFVNTLPD Mflv_1747|M.gilvum_PYR-GCK ATAFEDPTLFSMSVAENLRLGRP---DATDEDLRQAVEIAAAQFVYDLPF Mvan_5006|M.vanbaalenii_PYR-1 ATAFEDPTLFSMSVAENLRLGRP---EATDDDLRRAIDVAAAQFVYDLPF MSMEG_5660|M.smegmatis_MC2_155 ATAFEDPTLFSMSVAENLRLGRS---DATDDELEQAVEVAAAHFVYDLPF TH_2635|M.thermoresistible__bu ATAFEDPTLFSVSVEENLRLGRPPANPASDAELAEAIEIAAAEFVHDLPY MLBr_01113|M.leprae_Br4923 GMVLQDAWLFDGTIAENIAYGRP--QASEDEVMEAAKAAYVDRFVHTLSA MUL_4011|M.ulcerans_Agy99 GMVLQDTWLFDGTISENIAYGRP--EASPDDIIQAAKAAYVDRFVHMLPA MAV_1420|M.avium_104 GMVLQDTWLFDGTIAENIGYGRP--GAGDDEIVAAARAAYVDRFVQNLPD MAB_1415c|M.abscessus_ATCC_199 GLVPQRGYLFSGTVESNLRYGKA--DATEDEMWAALEVAQAAGFVRQHAA . . : **. :: *: *:. : ** . Mb0200|M.bovis_AF2122/97 GYQTAVGARGLTLSGGQRQRIALARALLHQPRLLIMDDPTSAVDAVIECG Rv0194|M.tuberculosis_H37Rv GYQTAVGARGLTLSGGQRQRIALARALLHQPRLLIMDDPTSAVDAVIECG MMAR_5223|M.marinum_M GYATPVGAQGLTLSGGQRQRIALARALVGNPRLLIMDEPTSAVDAVIEAS Mflv_1747|M.gilvum_PYR-GCK GLDTRIGEQGMSLSGGQRQRLSLARAILTRPRILVLDDTLSALDVHTEAV Mvan_5006|M.vanbaalenii_PYR-1 GLDTRIGEQGMSLSGGQRQRISLARAILADPRILVLDDTLSALDVHTEAV MSMEG_5660|M.smegmatis_MC2_155 GLDTRIGEQGMSLSGGQRQRLSLARAILAAPRILVLDDTLSALDVHTEAR TH_2635|M.thermoresistible__bu GLHTRIGEQGMSLSGGQRQRLSLARAVLAAPTILVLDDTLSALDVHTEAV MLBr_01113|M.leprae_Br4923 GYQTRVSGDGDNISAGEKQLITIARAFLARPQLLILDEATSSIDTRTEAL MUL_4011|M.ulcerans_Agy99 SYQTRISGDGSNISAGEKQLITIARAFLARPQLLILDEATSSVDTRTELL MAV_1420|M.avium_104 GYHTRVSGDGGNLSAGERQLITIARAFLARPQLLILDEATSSVDTRTEAL MAB_1415c|M.abscessus_ATCC_199 GLQMPVSQGGINFSGGQRQRIAIARAVIRRPGIYLFDDAFSALDVHTDAR . :. * .:*.*::* :::***.: * : ::*:. *::*. : Mb0200|M.bovis_AF2122/97 IQEVLREAIADRTAVIFTRRRSMLTLADRVAVLDS-----GRLLDVGTPD Rv0194|M.tuberculosis_H37Rv IQEVLREAIADRTAVIFTRRRSMLTLADRVAVLDS-----GRLLDVGTPD MMAR_5223|M.marinum_M IQDVLREVLADRTAVIFTRRRSMLSLADRVAVLDS-----GHLLDIGTPE Mflv_1747|M.gilvum_PYR-GCK VEEALRRVLHEVTGIVVAHRASTVLLADRVALLQN-----GTVTHVGTHA Mvan_5006|M.vanbaalenii_PYR-1 VEESLRRVLHDVTAIVVAHRASTVLLADRVALLRN-----GTITHVGTHA MSMEG_5660|M.smegmatis_MC2_155 VTEALSRVLSSVTGVIVAHRASTVLLADKVALLDRDAHGAGTVTHIGTHA TH_2635|M.thermoresistible__bu VTEALRRVLRDVTGIVVANRASTVLLADRVALLERVGPDGATITHVGTHA MLBr_01113|M.leprae_Br4923 IARATHDLLQDRTSFIIAHHLPTIRDADHILVVAA-----GKIVEQGSHA MUL_4011|M.ulcerans_Agy99 IARATAELRRDRTSFIIAHRLSTIRDADQILVVQA-----GQIVEHGTHA MAV_1420|M.avium_104 IAHATRELRRDRTSFIIAHRLSTIRDADRIAVIEA-----GRIFEQGTHA MAB_1415c|M.abscessus_ATCC_199 LRAALREVAADATVIVVAQRISTVADADQIVVLED-----GRVAATGTHA : . * .:.:.: . : **:: :: . : *: Mb0200|M.bovis_AF2122/97 EVWERCPRYRELLSPAPDLADDLVVAERSPVCRPVAGLGTKAAQHTNVHN Rv0194|M.tuberculosis_H37Rv EVWERCPRYRELLSPAPDLADDLVVAERSPVCRPVAGLGTKAAQHTNVHN MMAR_5223|M.marinum_M QLWGRCSRYRELLSPATDPLRSLAFEDGVPEPESEP-----EAIDVAADA Mflv_1747|M.gilvum_PYR-GCK ELLAGVPEYRYLLAADDELDDGSERE------------------------ Mvan_5006|M.vanbaalenii_PYR-1 ELLANVPEYRYLLAADDELDDGSERE------------------------ MSMEG_5660|M.smegmatis_MC2_155 ELLAEVPQYRYLLAADDELDDDTERT------------------------ TH_2635|M.thermoresistible__bu ELLADVPQYRYLLAADPDLDDGAEPTPXXXVR------AGTVATGSRSPT MLBr_01113|M.leprae_Br4923 KLLARRGAYYRMTQA----------------------------------- MUL_4011|M.ulcerans_Agy99 ELLANRGAYYAMTRA----------------------------------- MAV_1420|M.avium_104 ELLARRGVYYAMTQA----------------------------------- MAB_1415c|M.abscessus_ATCC_199 ELTRRCGTYREICDSQAVFA------------------------------ :: * : . Mb0200|M.bovis_AF2122/97 PGPHDHPPGPDPLRRLLREFRGPLALSLLLVAVQTCAGLLPPLLIRHGID Rv0194|M.tuberculosis_H37Rv PGPHDHPPGPDPLRRLLREFRGPLALSLLLVAVQTCAGLLPPLLIRHGID MMAR_5223|M.marinum_M TGPSDHSPKPDLLRRLLHDFRGPLIVSLLLVALETGAGLLPPLLIRHGID Mflv_1747|M.gilvum_PYR-GCK ---CDWERDEERARL---------DHEVLDGDVREREMLERRS------- Mvan_5006|M.vanbaalenii_PYR-1 ---CDWEEQEERARL---------DRDEECARV-DHEVLGRRA------- MSMEG_5660|M.smegmatis_MC2_155 ---CEWEDDEDLERLR-----RVHDERAAIDGLDEPEYLGQEVQRR---- TH_2635|M.thermoresistible__bu PTRCHPRRGSRRCRSRPPAAPRRPPRRPTSSGCRPAPGRSRRIRHRADGR MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MUL_4011|M.ulcerans_Agy99 -------------------------------------------------- MAV_1420|M.avium_104 -------------------------------------------------- MAB_1415c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0200|M.bovis_AF2122/97 VGIRRHVLSALWWAALAGTATVVIRWVVQWGSAMVAGYTGEQVLFRLRSV Rv0194|M.tuberculosis_H37Rv VGIRRHVLSALWWAALAGTATVVIRWVVQWGSAMVAGYTGEQVLFRLRSV MMAR_5223|M.marinum_M VGIRQHVLTALWWAALAGAAIVAIRLVAQWGSAVVAGTAGEKALFRLRSL Mflv_1747|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5006|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5660|M.smegmatis_MC2_155 -------------------------------------------------- TH_2635|M.thermoresistible__bu PGSSRRRSAGRRPSPSPRDSRGSDRGVPVAYTGYMSCSSRLVPVVSTTFA MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MUL_4011|M.ulcerans_Agy99 -------------------------------------------------- MAV_1420|M.avium_104 -------------------------------------------------- MAB_1415c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0200|M.bovis_AF2122/97 VFAHAQRLGLDAFEDDGDAQIVTAVTADVEAIVAFLRTGLVVAVISVVTL Rv0194|M.tuberculosis_H37Rv VFAHAQRLGLDAFEDDGDAQIVTAVTADVEAIVAFLRTGLVVAVISVVTL MMAR_5223|M.marinum_M VFAHAQRLDLDAFEDNGDSQIITAVTADVDAIVAFLRTGLVIAIVSLVTA Mflv_1747|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5006|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5660|M.smegmatis_MC2_155 -------------------------------------------------- TH_2635|M.thermoresistible__bu PMLSVQM------------------------------------------- MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MUL_4011|M.ulcerans_Agy99 -------------------------------------------------- MAV_1420|M.avium_104 -------------------------------------------------- MAB_1415c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0200|M.bovis_AF2122/97 VGILVALLAIRARLVLLIFTTMPVLALATWQFRRASNWTYRRARHRLGTV Rv0194|M.tuberculosis_H37Rv VGILVALLAIRARLVLLIFTTMPVLALATWQFRRASNWTYRRARHRLGTV MMAR_5223|M.marinum_M VGILAALLAINAKLALLIFATLPMLGLATWQFRRASSWTYRQARQRLGTV Mflv_1747|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5006|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5660|M.smegmatis_MC2_155 -------------------------------------------------- TH_2635|M.thermoresistible__bu -------------------------------------------------- MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MUL_4011|M.ulcerans_Agy99 -------------------------------------------------- MAV_1420|M.avium_104 -------------------------------------------------- MAB_1415c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0200|M.bovis_AF2122/97 TATLREYAAGLRIAQAFRAEYRGLQSYFAHSDDYRRLGVRGQRLLALYYP Rv0194|M.tuberculosis_H37Rv TATLREYAAGLRIAQAFRAEYRGLQSYFAHSDDYRRLGVRGQRLLALYYP MMAR_5223|M.marinum_M TATLREYSAGLRIAQAYRAEYVGFQTYFAHSDDYRRLRVRGQRLLALYFP Mflv_1747|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5006|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5660|M.smegmatis_MC2_155 -------------------------------------------------- TH_2635|M.thermoresistible__bu -------------------------------------------------- MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MUL_4011|M.ulcerans_Agy99 -------------------------------------------------- MAV_1420|M.avium_104 -------------------------------------------------- MAB_1415c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0200|M.bovis_AF2122/97 FVALLCSLATTLVLLDGAREVRAGVISVGALVTYLLYIELLYTPIGELAQ Rv0194|M.tuberculosis_H37Rv FVALLCSLATTLVLLDGAREVRAGVISVGALVTYLLYIELLYTPIGELAQ MMAR_5223|M.marinum_M LVPLTCSLATTLVLFEGGRDVQAGVLSVGALVTYLLYVEMLFAPVDKLSQ Mflv_1747|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5006|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5660|M.smegmatis_MC2_155 -------------------------------------------------- TH_2635|M.thermoresistible__bu -------------------------------------------------- MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MUL_4011|M.ulcerans_Agy99 -------------------------------------------------- MAV_1420|M.avium_104 -------------------------------------------------- MAB_1415c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0200|M.bovis_AF2122/97 MFDDYQRAAVAAGRIRSLLSTRTPSSPAARPVGTLRGEVVFDAVHYSYRT Rv0194|M.tuberculosis_H37Rv MFDDYQRAAVAAGRIRSLLSTRTPSSPAARPVGTLRGEVVFDAVHYSYRT MMAR_5223|M.marinum_M MFDEYQRAAVAVGRIRSLLNTPTAFSPSAAPVGTLRGEIEFDAVHFRYPT Mflv_1747|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5006|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5660|M.smegmatis_MC2_155 -------------------------------------------------- TH_2635|M.thermoresistible__bu -------------------------------------------------- MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MUL_4011|M.ulcerans_Agy99 -------------------------------------------------- MAV_1420|M.avium_104 -------------------------------------------------- MAB_1415c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0200|M.bovis_AF2122/97 REVPALAGINLRIPAGQTVVFVGSTGSGKSTLIKLVARFYDPTHGTVRVD Rv0194|M.tuberculosis_H37Rv REVPALAGINLRIPAGQTVVFVGSTGSGKSTLIKLVARFYDPTHGTVRVD MMAR_5223|M.marinum_M RDAPALAGINLRIPAGQTVVFVGSTGSGKSTLMKLVSRFYDPTDGIIRVD Mflv_1747|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5006|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5660|M.smegmatis_MC2_155 -------------------------------------------------- TH_2635|M.thermoresistible__bu -------------------------------------------------- MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MUL_4011|M.ulcerans_Agy99 -------------------------------------------------- MAV_1420|M.avium_104 -------------------------------------------------- MAB_1415c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0200|M.bovis_AF2122/97 GCDLREFDVDGYRNRLGIVTQEQYVFAGTVRDAIAYGRPDATDAQVERAA Rv0194|M.tuberculosis_H37Rv GCDLREFDVDGYRNRLGIVTQEQYVFAGTVRDAIAYGRPDATDAQVERAA MMAR_5223|M.marinum_M GCDLREFDIDGYRSRLSIVAQEPYLFAGTVRDAIAYGRPDATDAQVERAA Mflv_1747|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5006|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5660|M.smegmatis_MC2_155 -------------------------------------------------- TH_2635|M.thermoresistible__bu -------------------------------------------------- MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MUL_4011|M.ulcerans_Agy99 -------------------------------------------------- MAV_1420|M.avium_104 -------------------------------------------------- MAB_1415c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0200|M.bovis_AF2122/97 REVGAHPMITALDNGYLHQVTAGGRNLSAGQLQLLALARARLVDPDILLL Rv0194|M.tuberculosis_H37Rv REVGAHPMITALDNGYLHQVTAGGRNLSAGQLQLLALARARLVDPDILLL MMAR_5223|M.marinum_M REVGAHPMIAALDGGYQHEVAAGGRNLSAGQLQLLALARARLVDSDILLL Mflv_1747|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5006|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5660|M.smegmatis_MC2_155 -------------------------------------------------- TH_2635|M.thermoresistible__bu -------------------------------------------------- MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MUL_4011|M.ulcerans_Agy99 -------------------------------------------------- MAV_1420|M.avium_104 -------------------------------------------------- MAB_1415c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0200|M.bovis_AF2122/97 DEATVALDPATEAVVQRATLTLAARRTTLIVAHGLAIAEHADRIVVLEHG Rv0194|M.tuberculosis_H37Rv DEATVALDPATEAVVQRATLTLAARRTTLIVAHGLAIAEHADRIVVLEHG MMAR_5223|M.marinum_M DEATVALDPATEALVHWATLGLAADRTTLIIAHELAIAEFVDRIVVLEQG Mflv_1747|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5006|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5660|M.smegmatis_MC2_155 -------------------------------------------------- TH_2635|M.thermoresistible__bu -------------------------------------------------- MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MUL_4011|M.ulcerans_Agy99 -------------------------------------------------- MAV_1420|M.avium_104 -------------------------------------------------- MAB_1415c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0200|M.bovis_AF2122/97 TVVEDGAHTELLAAGGHYSRLWAAHTRLCSPEITQLQCIDA--------- Rv0194|M.tuberculosis_H37Rv TVVEDGAHTELLAAGGHYSRLWAAHTRLCSPEITQLQCIDA--------- MMAR_5223|M.marinum_M TIVEDGTHVELLAAGGRYAALWAAHSRVGRPSPSDDRPIPTELLVHSPDT Mflv_1747|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5006|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_5660|M.smegmatis_MC2_155 -------------------------------------------------- TH_2635|M.thermoresistible__bu -------------------------------------------------- MLBr_01113|M.leprae_Br4923 -------------------------------------------------- MUL_4011|M.ulcerans_Agy99 -------------------------------------------------- MAV_1420|M.avium_104 -------------------------------------------------- MAB_1415c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0200|M.bovis_AF2122/97 --- Rv0194|M.tuberculosis_H37Rv --- MMAR_5223|M.marinum_M DVL Mflv_1747|M.gilvum_PYR-GCK --- Mvan_5006|M.vanbaalenii_PYR-1 --- MSMEG_5660|M.smegmatis_MC2_155 --- TH_2635|M.thermoresistible__bu --- MLBr_01113|M.leprae_Br4923 --- MUL_4011|M.ulcerans_Agy99 --- MAV_1420|M.avium_104 --- MAB_1415c|M.abscessus_ATCC_199 ---